Identification
Personal identification
- Full name
- Mariana Reis
Citation names
- Reis, Mariana
Author identifiers
- Ciência ID
- 7211-A693-9E30
- ORCID iD
- 0000-0001-8737-2138
- Researcher Id
- H-8235-2017
Addresses
- CIIMAR | Interdisciplinary Centre of Marine and Environmental Research of the University of Porto. Terminal de Cruzeiros do Porto de Leixões Avenida General Norton de Matos, S/N, 4450-208, Matosinhos, Matosinhos, Portugal (Professional)
Websites
- https://orcid.org/0000-0001-8737-2138 (Professional)
- www.cyancan.wixsite.com/cyancan (Professional)
Knowledge fields
- Exact Sciences - Chemical Sciences - Organic Chemistry
Languages
Language | Speaking | Reading | Writing | Listening | Peer-review |
---|---|---|---|---|---|
English | Advanced (C1) | Advanced (C1) | Advanced (C1) | Advanced (C1) | |
French | Beginner (A1) | Elementary (A2) | Beginner (A1) | Beginner (A1) | |
Spanish; Castilian | Beginner (A1) | Beginner (A1) | Beginner (A1) | Beginner (A1) | |
German | Beginner (A1) | Beginner (A1) | Beginner (A1) | Beginner (A1) |
Education
Degree | Classification | |
---|---|---|
2015
Concluded
|
Farmácia (Doutoramento)
Universidade de Lisboa Faculdade de Farmácia, Portugal
"Terpenoids as effective compounds for overcoming multidrug resistance in cancer cells" (THESIS/DISSERTATION)
|
Louvor e Distinção |
2009
Concluded
|
Ciências Biomédicas (Mestrado)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
"Toxocara canis: procura de novos tratamentos na medicina tradicional – estudo in vitro e in vivo" (THESIS/DISSERTATION)
|
18 |
2005
Concluded
|
Biologia Celular e Biotecnologia (Licenciatura)
Universidade de Lisboa Faculdade de Ciências, Portugal
"." (THESIS/DISSERTATION)
|
15 |
Affiliation
Science
Category Host institution |
Employer | |
---|---|---|
2019/01/01 - 2021 | Researcher (Research) | Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal |
2016/06 - 2018/12 | Postdoc (Research) | Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal |
2010/04 - 2015/03 | Researcher (Research) | Universidade de Lisboa Faculdade de Farmácia, Portugal |
2011 - 2015 | Visiting Researcher (Research) | Charité Universitätsmedizin Berlin, Germany |
2010 - 2015 | Visiting Researcher (Research) | University of Szeged, Hungary |
2006 - 2009 | Research Trainee (Research) | Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal |
2005 - 2006 | Research Trainee (Research) | Alfred-Wegener-Institut für Polar- und Meeresforschung Biologische Anstalt Helgoland, Germany |
Projects
Grant
Designation | Funders | |
---|---|---|
2011/04/01 - 2015 | TERPENOIDS AS EFFECTIVE COMPOUNDS FOR OVERCOMING MULTIDRUG RESISTANCE IN CANCER CELLS
info:eu-repo/grantAgreement/FCT/SFRH/SFRH2%FBD2%F729152%F2010/PT
Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
|
Fundação para a Ciência e a Tecnologia
Concluded
|
Contract
Designation | Funders | |
---|---|---|
2022 - Current | PROPELLER: INVESTIGATION OF A NEW CLASS OF BETA-PROPELLER ENZYMES
PTDC/BIABQM/5760/2020
Co-Principal Investigator (Co-PI)
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
|
Ongoing
|
2022 - 2023 | BLUEBIOLAB: TRANSBOUNDARY MARINE BIOTECHNOLOGY LABORATORY
0474_BLUEBIOLAB_1_E
Researcher
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
|
|
2020 - 2023 | ATLANTIDA - Platform for the monitoring of the North Atlantic ocean and tools for the sustainable exploitation of the marine
resources
NORTE-01-0145-FEDER-000040
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
|
|
2019 - 2022 | ANTIBACFILM: NOVEL MARINE BIOMOLECULE WITH ANTIBIOFILM ACTIVITY
POCI-01-0145-FEDER-042736
Principal investigator
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
|
|
2018/09/01 - 2021/08/31 | Novel eco-friendly Antifouling Strategies based on Cyanobacterial bioactivE Metabolites
PTDC/BTA-BTA/31422/2017
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
|
Fundação para a Ciência e a Tecnologia
Ongoing
|
2018/07 - 2021/06 | CYANCAN- Uncovering the cyanobacterial chemical diversity: the search for novel anticancer compounds
Principal investigator
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
|
Ongoing
|
2018 - 2021 | NASCEM - Novel eco-friendly antifouling strategies based on cyanobacterial bioactive metabolites
PTDC/BTA-BTA/31422/2017
Researcher
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
|
|
2018 - 2021 | HALVERSITY - Genetic and chemical diversity of a novel halogenase class
PTDC/BIA-BQM/29710/2017
Researcher
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
|
|
2018 - 2020 | Cyanobesity - Cyanobacteria as a source of bioactive compounds with effects on obesity and obesity-related co-morbidities
ERA-MBT/0001/2015
Researcher
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
|
Concluded
|
2016 - 2018 | NOMORFILM: Novel marine biomolecules against biofilm. Application to medical devices
634588
Post-doc Fellow
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
|
Ongoing
|
2012 - 2015 | Optimization of P-glycoprotein modulators and insights into the efflux mechanism
PTDC/QEQ-MED/0905/2012
PhD Student Fellow
Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
|
Fundação para a Ciência e a Tecnologia, I.P. |
2011/01/01 - 2013/12/31 | Projecto Estratégico - UI 74 - 2011-2012
PEst-OE/SAU/UI0074/2011
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
|
Fundação para a Ciência e a Tecnologia
Concluded
|
2010 - 2011 | Diterpenes as lead compounds for overcoming multidrug resistance (MDR) in cancer cells: P-glycoprotein modulators and antiproliferative
agents
PTDC/QUI-QUI/099815/2008
Research Fellow
Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
|
Concluded
|
2006 - 2008 | Plankton*net: An open-access frame-work for developing and supporting distributed knowledge centers for taxonomic data a pilot
study targeting EU phytoplankton
Scientific Initiation Fellow
|
Other
Designation | Funders | |
---|---|---|
2023 - Current | AquaBakillus Bacillus spp. as source of bioactive compounds for aquaculture bacterial diseases control
AquaBakillus
Co-Principal Investigator (Co-PI)
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
|
|
2023 - Current | Type II polyketide Investigation of type II polyketide synthases in cyanobacteria
Type II polyketide
Co-Principal Investigator (Co-PI)
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
|
Outputs
Publications
Book chapter |
|
Conference abstract |
|
Conference paper |
|
Conference poster |
|
Journal article |
|
Journal issue |
|
Thesis / Dissertation |
|
Website |
|
Intellectual property
Patent |
|
Provisional application for patent |
|
Activities
Oral presentation
Presentation title | Event name Host (Event location) |
|
---|---|---|
2022/09 | Bioactivity Screening of Cyanobacteria with Anti-Diabetic Potential using Zebrafish as Model Organism | Blue Think Conference 2021
CIIMAR (Matosinhos, Portugal)
|
2022/07 | Uncovering the cyanobacterial chemical diversity: the search for novel anticancer compounds | 7th Iberian Congress on Cyanotoxins/3rd Iberoamerican Congress on Cyanotoxins
(Ponta Delgada, Portugal)
|
2022/05 | New cytotoxic macrolide-type compound isolated from a cyanobacterium | Trends in Natural Products Research: A PSE’S Young Scientist Meeting
PSE (Greece)
|
2021/08 | Cyanobacterial Bioactive Nucleosides with Antifouling Properties | 1st International Congress of Biotechnology and Bioengineering / 5th Peruvian Congress of Biotechonology and Bioengineering
(Arequipa, Peru)
|
2021/08 | Discovery of novel biological active metabolites from cyanobacteria and actinobacteria: Cytotoxic, Anti-Obesity and Appetite Reduction Effects | 1st International Congress of Biotechnology and Bioengineering/5th Peruvian Congress Biotechnology and Bioengineering
(Arequipa, Peru)
|
2021 | Combination of metabolomic tools and bioactivity screening as a strategy to find hit anticancer compounds from a library of cyanobacterial fractions | Blue Think Conference ¿ Share Science, Spread Knowledg
(Matosinhos, Portugal)
|
2019/09/27 | Strategies to explore the chemical diversity of Cyanobacteria | I Bio.Natural – Bioactive Natural Products Research Meeting
(li, Portugal)
|
2019/02/18 | Uncovering the cyanobacterial chemical diversity | COST Action CM1407 - Challenging organic syntheses inspired by nature - from natural products chemistry to drug discovery
(Brussels, Belgium)
|
2016/05 | Cancer multidrug resistance reversal: the role of macrocyclic diterpenes as ABCB1 modulators and selective cell death inductors | 6th International Congress of Aromatic and Medicinal Plants (CIPAM 2016)
(Coimbra, Portugal)
|
2015/12 | Surpassing multidrug resistance in cancer: a study on jolkinol D derivatives. | Congresso Química Orgânica e Química Terapêutica
(Porto, Portugal)
|
2015 | Tackling Multidrug Resistance in Cancer | I International Summer School on Natural Products
(Naples, Italy)
|
2015 | Can macrocyclic diterpenes reverse cancer multidrug resistance? | Multidrug resistance workshop
iMed.ULisboa
|
2014/09 | Diterpenic compounds with selective antiproliferative activity in multidrug resistant cancer cells. | 62nd International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research
(Portugal)
|
2014/09 | Jolkinol D and its derivatives: anti-proliferative selectivity towards multi-drug resistant cancer cells | 1st EFMC Young Medicinal Chemist Symposium |
2014/07 | Diterpenic compounds: tackling multidrug resistant cancer phenotypes | 6th iMed.UL Post-Graduate Students Meeting
(Lisboa, Portugal)
|
2012 | Terpenoids as effective compounds for overcoming multidrug resistance in cancer cells. | iMed.UL
iMed.UL
|
2011 | Macrocylic lathyrane diterpenoids from Euphorbia piscatoria - Their potential as MDR reversal agents in cancer cells | 3rd iMed.UL Post-Graduate Students Meeting |
2010 | Phytochemicals: its application in vector control and treatment of parasitic diseases Lecture: Medicinal plants in the control of helminths | XI Iberian Congress of Parasitology |
2009 | In vitro and in vivo anthelmintic activity of plant extracts and dietary supplements against Toxocara canis | 2º Congresso Iberoamericano de Fitoterapia |
2008 | Toxocara canis: procura de novos tratamentos na medicina tradicional - estudo in vitro. | Congresso Nacional de Doenças Infecciosas / Microbiologia Clínica, SIDA e Parasitologia |
Supervision
Thesis Title Role |
Degree Subject (Type) Institution / Organization |
|
---|---|---|
2023/03/01 - Current | Cyanobacteria and drug discovery: advances and novel approaches to exploit the prolific
production of anticancer compounds
Supervisor
|
Universidade do Porto Faculdade de Ciências, Portugal
|
2023 - Current | Awakening the sleeping potential in estuarine, hypersaline and intertidal cyanobacteria for the production of novel bioactive
compounds with biotechnological applications
Co-supervisor
|
Universidade do Porto Faculdade de Ciências, Portugal
|
2021/02/01 - Current | Exploration of microalgae and cyanobacteria for metabolic diseases
Co-supervisor
|
Biotecnologia Marinha e Aquacultura (PhD)
Universidade do Porto Faculdade de Ciências, Portugal
|
2021 - Current | Cyanobacteria as an economically and sustainable base for carotenoids and phycobiliproteins production – employment of multi
stress factors for culture optimization and evaluation of the bioactive potential
Co-supervisor
|
Universidade do Porto Faculdade de Ciências, Portugal
|
2019 - Current | Zebrafish larvae as a physiologically relevant model system to discover novel cyanobacterial products with human health applications
Co-supervisor
|
Marine Biotechnology and Aquaculture (PhD)
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
Universidade do Porto Faculdade de Ciências, Portugal |
2023/09 - 2024/09 | Exploring Bacillus spp. bioactive compounds as a novel strategy to prevent fish bacterial infections
Co-supervisor
|
Applications in Biotechnology and Synthetic Biology (Master)
Universidade do Porto Faculdade de Ciências, Portugal
|
2022/09 - 2023/11 | Alzheimer’s Disease: Assessing the Therapeutic Potential of Marine Cyanobacteria
Co-supervisor
|
Bioquímica em Saúde – Ramo em Bioquímica Clínica e Metabólica (Master)
Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
|
2022/09 - 2023/11 | Stalling the course of Alzheimer’s Disease: can cyanobacteria be a new approach toward therapy?
Co-supervisor
|
Bioquímica em Saúde – Ramo em Bioquímica Clínica e Metabólica (Master)
Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
|
2022/09/01 - 2023/07/01 | Chlorophyll derivatives with anti-obesity activity
Co-supervisor
|
Biologia Funcional e Biotecnologia de Plantas (Master)
Universidade do Porto Faculdade de Ciências, Portugal
|
2022 - 2023 | OSMaC strategies for the discovery of new natural products
Supervisor
|
Mestrado em Microbiologia Aplicada - ESB-UCP (Master)
Universidade Católica Portuguesa, Portugal
|
2022/06 - 2022/10 | Isolation of new cyanobacterial natural products from Hapalosiphon sp. Jm_013
Co-supervisor
|
Máster Universitario en Biotecnología Azul Aplicada (Master)
Universidad Católica de Valencia San Vicente Mártir Facultad de Veterinaria y Ciencias Experimentales, Spain
|
2021/09/01 - 2022/09/01 | Discovery of cyanobacterial anticancer compounds using 3D cell culture models
Supervisor
|
Biotechnology with specialization in industrial and environmental biotechnology (Master)
Universidade de Aveiro, Portugal
|
2022/02/01 - 2022/07/01 | Isolation of new cyanobacterial natural products from cultured strains
Co-supervisor
|
Biotechnology (Master)
Universidad Católica de Valencia San Vicente Mártir Facultad de Veterinaria y Ciencias Experimentales, Spain
|
2022/01/01 - 2022/07/01 | The isolation of cyanobacterial compounds with anticancer potential
Supervisor
|
Biotechnology (Master)
Université de La Rochelle, France
|
2018 - 2019 | Discovery of novel compounds from cyanobacteria for the treatment of obesity
Co-supervisor
|
Contamination and Environmental Toxicology (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
|
2017 - 2018 | Bioactivity screening of marine cyanobacteria for the isolation of novel compounds for obesity related co-morbidities
Co-supervisor
|
Contamination and Environmental Toxicology (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
|
Event organisation
Event name Type of event (Role) |
Institution / Organization | |
---|---|---|
2018 - Current | CIIMAR seminar series: Neptune (junior researchers), Oceanus (senior researchers) and Nautilus (out-of-the-box) (2018)
Seminar (Member of the Organising Committee)
|
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal |
2023 - 2024 | 8th Congress of the International Society for Applied Phycology (2023 - 2024)
Conference (Member of the Organising Committee)
|
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal |
2019 - 2019 | Natural Products in Drug Discovery and Human Health (NatProdDDH) conference held in Lisbon, Portugal, on July 28-31, 2019.
(2019/07)
Congress (Member of the Organising Committee)
|
Universidade de Lisboa Faculdade de Farmácia, Portugal |
Jury of academic degree
Topic Role |
Candidate name (Type of degree) Institution / Organization |
|
---|---|---|
2022/10/14 | Exploiting cyanobacterial metabolism to unveil new natural products and inquire about beta-oxidation
(Thesis) Main arguer
|
Bárbara Rêgo e Pires (Master)
Universidade do Porto Faculdade de Ciências, Portugal
|
2022/10/04 | Desenvolvimento de novos inibidores da necroptose direcionados à RIPK1
(Thesis) Main arguer
|
Beatriz Chaves Cambaio (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
|
2022/02/25 | Development of new alkaloid derivatives as multidrug resistance reversers in cancer cells
(Thesis) Main arguer
|
Rita Mestre Vieira (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
|
2021/02/26 | Síntese e avaliação biológica de novos compostos antitumorais derivados
de triazenos
(Thesis) Main arguer
|
Catarina Teixeira António (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
|
2021/02/11 | Generation of a library of diterpene derivatives for restoring antibiotic activity against resistant bacterial strains
(Thesis) Main arguer
|
Bernardo Manuel Moreira Simões Vieira (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
|
2020/11/05 | Bioactivity screening of cyanobacteria for appetite reduction
(Thesis) Main arguer
|
Daniela Ferreira (Master)
Instituto Politécnico do Porto, Portugal
|
2020/04/29 | Pesquisa de atividade biológica de extratos de seis espécies de Plectranthus: P. cylindraceus, P. petiolaris, P.spicatus,
P. swynnertonii, P. welwitchii e P. woodii
(Thesis) Main arguer
|
Cláudia de Fátima Santos Oliveira (Master)
Universidade Lusófona de Humanidades e Tecnologias, Portugal
|
2020/04/24 | Avaliação da Atividade Biológica dos Extratos de Plactranthus mutabilis, P. ciliatus, P. xerophilus, P. crassus e P. lucidus
(Thesis) Main arguer
|
Carolina Isabel Faustino Pereira de Oliveira (Master)
Universidade Lusófona de Humanidades e Tecnologias, Portugal
|
2019/12/20 | ANTIBACTERIAL ACTIVITY OF THE CHEMICAL CONTITUENTS OF THE AFRICAN MEDICINAL PLANT GREWIA HEXAMITA AGAINST RESISTANT BACTERIA
(Thesis) Main arguer
|
Sara Filipa Santos do Jogo (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
|
2018/07/13 | Desenvolvimento de moléculas híbridas para o tratamento do melanoma maligno metastático
(Thesis) Main arguer
|
Andreia Filipa Alcanena Gonçalves (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
|
2018/06/26 | Manipulation of cyanobacterial culture conditions to increase the production of bioactive compounds for the treatment of obesity
and related diseases
(Thesis) Main arguer
|
David Duarte Costa Fernandes (Other)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
|
2017/09/07 | ISOLAMENTO E CARACTERIZAÇÃO DE COMPOSTOS BIOACTIVOS ORIUNDOS DE CIANOBACTÉRIAS
(Thesis) Main arguer
|
Ana Salomé Dias (Other)
Universidade do Porto Faculdade de Ciências, Portugal
|
Committee member
Activity description Role |
Institution / Organization | |
---|---|---|
2020 - Current | CIIMAR spin-off commission
Member
|
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal |
Course / Discipline taught
Academic session | Degree Subject (Type) | Institution / Organization | |
---|---|---|---|
2021/01/28 - Current | Marine Natural Products: from the sea to the shelf Nutraceuticals, Cosmeceuticals and Pharmaceuticals | Produtos de Saúde e Suplementos Alimentares (Mestrado) | Universidade Lusófona de Humanidades e Tecnologias, Portugal |
2017 - 2020 | Marine natural products | Applied Blue Biotechnology International Master (Master) | Université de La Rochelle, France |
2019 - 2019 | Isolation of natural products -Blue Biotechnology Advanced Tools e-learning course | (Outros) | Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal |
2018 - 2018 | Isolation of natural products and Structural elucidation of natural products (hands-on) Marine Natural Products: Discovery and Structure Elucidation course | Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal |
Evaluation committee
Activity description Role |
Institution / Organization | Funding entity | |
---|---|---|---|
2020 - 2020 | BYT PhD Program of CIIMAR: selection of candidates
Evaluator
|
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal |
Journal scientific committee
Journal title (ISSN) | Publisher | |
---|---|---|
2021 - Current | Fronteirs in Pharmacology - Ethnopharmacology | |
2020/04 - 2020/09 | Frontiers in Pharmacology Translational Pharmacology | |
2019 - 2019 | Journal of Chemistry: Medicinal Chemistry | Hindawi |
Mentoring / Tutoring
Topic | Student name | |
---|---|---|
2019 - 2020 | Awakening the sleeping beauty: OSMaC strategies for the production of new compounds | Beatriz Maria Dias Ramos |
Distinctions
Award
2016 | Best oral communication. 6th International Congress of Aromatic and Medicinal Plants (CIPAM 2016) |
2015 | Fellowship for the ISSNP 2015.1st International Summer School in Natural Products (ISSNP) scientific committee |
2015 | Best poster. iMed.UL Post-Graduate Students Meeting scientific committee |
2014 | Best poster 62nd International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research |
2011 | Full Travel Scholarship to ESPCA on Natural Products, Medicinal Chemistry and Organic Synthesis, Campinas, São Paulo, Brazil.
Brazilian Chemical Society, Brazil
São Paulo State University (UNESP), Brazil University of Campinas (UNICAMP), the University of São Paulo (USP) and the Federal University of São Carlos (UFSCar), Brazil |