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Ana Rita Monteiro is a Nanosciences and Nanotechnology PhD student at University of Aveiro since 2018 (FCT PhD scholarship). Her research is focused on the synthesis and characterization of new anticancer hybrid materials comprising carbon nanomaterials (graphene oxide and graphene quantum dots) and tetrapyrrolic macrocyles (porphyrins). She graduated in Biochemistry (2016) and obtained her Master degree in Chemistry (2018) at University of Aveiro. During her studies, she completed extracurricular courses and internships at ICBAS/FEUP (2016), INL (2017) and Università degli Studi di Padova (Erasmus+, 2018). Her main research interests are nanochemistry, medicinal chemistry, organic chemistry and biochemistry.
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Identification

Personal identification

Full name
Ana Rita Rodrigues Vilares Cabral Monteiro

Author identifiers

Ciência ID
7410-66EE-FE16
ORCID iD
0000-0003-2528-943X

Addresses

  • Rúa de Jenaro de la Fuente, Santiago de Compostela, A Coruña, 15705, Santiago de Compostela, A Coruña, Spain (Professional)
Education
Degree Classification
2018/09/15 - 2023/03/15
Ongoing
 Nanociências e Nanotecnologia (Doutoramento)
Universidade de Aveiro Departamento de Química, Portugal
"Porphyrin functionalized graphene oxide for telomerase inhibition" (THESIS/DISSERTATION)
2019/08/01 - 2019/08/31
Concluded
 German as a foreign language for international students (intensive summer course) (Outros)
Eberhard Karls Universität Tübingen, Germany
 B1.2
2018
Concluded
 Química (Mestrado)
Universidade de Aveiro, Portugal
"Hybrids of porphyrins and graphene oxide for biological applications" (THESIS/DISSERTATION)
 18
2016
Concluded
 Bioquímica (Licenciatura)
Universidade de Aveiro, Portugal
"Stability studies of DNA/porphyrin adducts" (THESIS/DISSERTATION)
 18
Outputs

Publications

Conference abstract
  1. A. R. Monteiro; C. I. V. Ramos; L. M. O. Lourenço; S. Fateixa; J. Rodrigues; M. G. P. M. S. Neves; T. Trindade. "Graphene Oxide Assisted Delivery of Cationic Zn(II) Phthalocyanines to DNA G-Quadruplexes". Paper presented in 14th National Organic Chemistry Meeting & 7th National Medicinal Chemistry Meeting (14ENQO&7ENQT), Lisboa, 2022.
  2. A. R. Monteiro; M. G. P. M. S. Neves; T. Trindade. "Carbon-based nanomaterials functionalized with porphyrins for cancer therapies". Paper presented in Research Summit, Aveiro, 2021.
  3. A. R. Monteiro; L. Menilli; S. Lazzarotto; F. Morais; A. Gomes; N. M. M. Moura; S. Fateixa; et al. "Antiproliferative activity of cationic porphyrins functionalized with graphene oxide and graphene quantum dots in cancer cells". Paper presented in Photodynamic Therapy and Photodiagnosis (PDT-PDD), 2020.
  4. A. R. Monteiro; M. G. P. M. S. Neves; T. Trindade. "2D nanomaterials functionalized with porphyrins for cancer therapies". Paper presented in Research Summit, Aveiro, 2020.
  5. A. R. Monteiro; C. I. V. Ramos; S. Fateixa; N. M. M. Moura; M. G. P. M. S. Neves; T. Trindade. "Porphyrin@GO hybrid materials as DNA G-quadruplex detectors and stabilizers". Paper presented in International Conference on Nanomaterials Science and Mechanical Engineering, Aveiro, 2018.
    Accepted
  6. A. R. Monteiro; C. I. V. Ramos; M. G. P. M. S. Neves. "Stability studies of DNA/porphyrin adducts". Paper presented in 34th Youth Science Meeting (YSM), Lisboa, 2016.
Conference poster
  1. Monteiro, Ana R.; C. I. V. Ramos; L. M. O. Lourenço; S. Fateixa; J. Rodrigues; M. G. P. M. S. Neves; T. Trindade. Corresponding author: M. G. P. M. S. Neves. "DNA G-quadruplexes recognition by cationic zinc(II) phthalocyanine and graphene oxide hybrid materials". Paper presented in 19th Congress of the European Society for Photobiology, 2021.
  2. C. I. V. Ramos; A. R. Monteiro; N. M. M. Moura; T. Trindade; M. A. F. Faustino; M. G. P. M. S. Neves. "Metalloporphyrins: promising G-quadruplex stabilizing ligands". Paper presented in 19th Congress of the European Society for Photobiology, 2021.
  3. A. R. Monteiro; C. I. V. Ramos; L. M. O. Lourenço; S. Fateixa; J. Rodrigues; M. G. P. M. S. Neves; T. Trindade. "Immobilization of Zinc(II) Phthalocyanines on Graphene Oxide for DNA Recognition". Paper presented in International Symposium on Medicinal Chemistry of the European Federation for Medicinal Chemistry and Chemical Biology, 2021.
  4. Monteiro, Ana R.; M. G. P. M. S. Neves; T. Trindade. Corresponding author: M. G. P. M. S. Neves. "Functionalization of graphene oxide with porphyrins and terpyridine-like compounds via non-covalent interactions". Paper presented in 13th National Organic Chemistry Meeting & 6th National Medicinal Chemistry Meeting (13ENQO&6ENQT), 2020.
  5. Monteiro, Ana R.; L. Menilli; S. Lazzarotto; F. Morais; A. Gomes; N. M. M. Moura; S. Fateixa; et al. "Photocytotoxicity of porphyrin@GO hybrids against cancer cells". Paper presented in 8th Iberian Meeting on Colloids and Interfaces (RICI8), 2019.
  6. Ana R. Monteiro; L. Menilli; S. Lazzarotto; F. Morais; A. Gomes; N. M. M. Moura; S. Fateixa; et al. "Photocytotoxicity of porphyrin@GO hybrids against cancer cells". Paper presented in Jornadas do CICECO, 2019.
Journal article
  1. Ana R. Monteiro; Catarina I. V. Ramos; Sara Fateixa; Neves M.G.P.M.S.; Tito Trindade. "Arrays of graphene-quantum dots-supported DNA oligonucleotides as self-indicating porphyrin carriers". New Journal of Chemistry (2023): http://dx.doi.org/10.1039/d3nj03280a.
    10.1039/d3nj03280a
  2. "Interfacial assembly of zinc(II) phthalocyanines on graphene oxide (GO): Stable “turn-off-on” nanoplatforms to detect G-quadruplexes (G4)". Journal of Colloid and Interface Science 627 (2022): 900-912. http://dx.doi.org/10.1016/j.jcis.2022.07.075.
    10.1016/j.jcis.2022.07.075
  3. Catarina I. V. Ramos; Ana R. Monteiro; Nuno M. M. Moura; Maria Amparo F. Faustino; Tito Trindade; Maria Graça P. M. S. Neves. "The Interactions of H2TMPyP, Analogues and Its Metal Complexes with DNA G-Quadruplexes—An Overview". Biomolecules 11 10 (2021): 1404-1404. https://doi.org/10.3390/biom11101404.
    10.3390/biom11101404
  4. "Graphene Oxide and Graphene Quantum Dots as Delivery Systems of Cationic Porphyrins: Photo-Antiproliferative Activity Evaluation towards T24 Human Bladder Cancer Cells". Pharmaceutics 13 9 (2021): 1512-1512. http://dx.doi.org/10.3390/pharmaceutics13091512.
    10.3390/pharmaceutics13091512
  5. "Functionalization of Graphene Oxide with Porphyrins: Synthetic Routes and Biological Applications". ChemPlusChem (2020): http://dx.doi.org/10.1002/cplu.202000455.
    10.1002/cplu.202000455
  6. Monteiro, Ana R.; Ramos, Catarina I. V.; Fateixa, Sara; Moura, Nuno M. M.; Neves, Maria G. P. M. S.; Trindade, Tito. "Hybrids Based on Graphene Oxide and Porphyrin as Tools for Detection and Stabilization of DNA G-Quadruplexes". ACS Omega 3 9 (2018): 11184-11191. http://dx.doi.org/10.1021/acsomega.8b01366.
    Open access • Published • 10.1021/acsomega.8b01366
Thesis / Dissertation
  1. "Hybrids of porphyrins and graphene oxide for biological applications". Master, Universidade de Aveiro, 2018. http://hdl.handle.net/10773/25424.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2022/04/20 Graphene Oxide Assisted Delivery of Cationic Zn(II) Phthalocyanines to DNA G-Quadruplexes 14th National Organic Chemistry Meeting & 7th National Medicinal Chemistry Meeting (14ENQO&7ENQT)
Sociedade Portuguesa de Química (Aveiro, Portugal)
2021/09/07 Carbon-based nanomaterials functionalized with porphyrins for cancer therapies Research Summit
Universidade de Aveiro (Aveiro, Portugal)
2020/11/05 Antiproliferative activity of cationic porphyrins functionalized with graphene oxide and graphene quantum dots in cancer cells Photodynamic Therapy and Photodiagnosis (PDT-PDD)
2020/06/24 2D nanomaterials functionalized with porphyrins for cancer therapies Research Summit
Universidade de Aveiro (Aveiro, Portugal)
2019/06/11 Pitch Rising Science Communicator: the story of my PhD Jornadas do CICECO
CICECO, University of Aveiro (Aveiro, Portugal)
2018/07/18 Porphyrin@GO hybrid materials as DNA G-quadruplex detectors and stabilizers International Conference on Nanomaterials Science and Mechanical Engineering
Universidade de Aveiro (Aveiro, Portugal)
2016/07/24 Stability studies of DNA/porphyrin adducts 34th Youth Science Meeting (YSM)
Youth Science Association (Lisboa, Portugal)

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2021/10/01 - 2021/12/31 UT Austin Portugal: Interdisciplinary Training on Principles, Applications and Nanotechnology Innovation in Pharmaceutical Sciences, Biological Engineering and Medicine
2016/07/01 - 2016/07/31 Pharmaceuticals: how to obtain them, how they act and why - a perspective from Medicinal Chemistry and Pharmaceutical Industry
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Universidade do Porto Faculdade de Farmácia, Portugal

Association member

Society Organization name Role
2021/03/01 - 2021/10/31 Young Scientist Network of the European Federation of Medicinal Chemistry (EFMC) Mentee at the 1st Mentoring Programme

Scientific expedition

Activity description Institution / Organization
2018/02/15 - 2018/06/15 Erasmus+ Internship: evaluation of porphyrins and porphyrin@GO as photodynamic therapy (PDT) agents in bladder cancer cells Università degli Studi di Padova Dipartimento di Scienze del Farmaco, Italy
2017/06/30 - 2017/08/30 Analysis of cancer cells in microdroplets by means of surface-enhanced Raman scattering (SERS) spectroscopy International Iberian Nanotechnology Laboratory, Portugal
Distinctions

Award

2021 Best Poster at the 19th Congress of the European Society for Photobiology (ESP)
European Society for Photobiology, Austria
2020 Best Pitch at the Research Summit 2020
Universidade de Aveiro, Portugal
2019 Best Poster at the 8th Iberian Meeting on Colloids and Interfaces (RICI8)
2016 3rd Award for an Oral Communication at the 34th Youth Science Meeting (YSM)
2014 Best 1st year student in science and technology courses