Mayara Roncaglia dos Santos (7513-0B22-9A89)

Curriculum Vitae

Mayara Roncaglia dos Santos

Mayara Roncaglia dos Santos graduated with a degree in Chemical Technology from the Institute of Chemistry at UNICAMP in 2017. She completed her MSc in Advanced Methods and Accreditation in Chemical Analysis at the Faculty of Sciences, University of Porto, in 2022. Her master's dissertation focused on evaluating the performance of flow cells for pesticide determination. Currently, she is pursuing a PhD at FCUP-CIQUP (Center for Research in Chemistry of the University of Porto). Mayara specializes in the field of Exact Sciences with a focus on Nanochemistry, particularly lipid nanoparticles. Her expertise includes developing analytical methods and fluid mechanics. In Biochemistry, she emphasizes protein biochemistry, molecular biology, and large-scale recombinant protein production. Her experience in Organic Chemistry involves the synthesis and characterization of chiral compounds, while in Analytical Chemistry, she focuses on drug stability studies and quality control.

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Identification

Personal identification

Full name: Mayara Roncaglia dos Santos
Date of birth: 1988/10/06
Gender: Female

Citation names

Santos, Mayara
Roncaglia dos Santos, Mayara

Author identifiers

Ciência ID: 7513-0B22-9A89
ORCID iD: 0000-0002-5645-7216

Email addresses

mayara.santos@fc.up.pt (Professional)
up201900709@up.pt (Professional)

Knowledge fields

Exact Sciences - Chemical Sciences - Analytical Chemistry
Exact Sciences - Chemical Sciences - Organic Chemistry
Medical and Health Sciences - Basic Medicine - Medicinal Chemistry
Natural sciences - Biological Sciences - Biochemistry
Engineering and Technology - Nano-technology - Nano-materials

Languages

Language	Speaking	Reading	Writing	Listening	Peer-review
English	Advanced (C1)	Advanced (C1)	Advanced (C1)	Advanced (C1)	Advanced (C1)
Portuguese (Mother tongue)

Education

	Degree	Classification
2023/10/01 - 2027/09/30 Ongoing	Chemistry (Doutoramento) Universidade do Porto Faculdade de Ciências, Portugal "Development of natural-based nanostructured lipid carriers for controlled drug delivery and treatment of myocardial infarction" (THESIS/DISSERTATION)
2023/02/01 - 2023/07/01 Ongoing	Advanced Studies in Technological and Scientific Project (Especialização pós-licenciatura) Universidade do Porto Faculdade de Ciências, Portugal
2019/09/15 - 2022/12/06 Concluded	Master in Advanced Methods and Accreditation in Chemical Analysis (Mestrado) Universidade do Porto Faculdade de Ciências, Portugal "Performance evaluation of detector flow cells in liquid chromatography" (THESIS/DISSERTATION)	18
2013/03/01 - 2017/12/31 Concluded	Chemistry (Bachelor) Universidade Estadual de Campinas, Brazil	13

Affiliation

Science

	Category Host institution	Employer
2023/10/01 - Current	Researcher (Research)	Fundação para a Ciência e a Tecnologia, Portugal
	Universidade do Porto Faculdade de Ciências, Portugal
2023/07/15 - 2023/09/30	Researcher (Research)	Universidade do Porto Faculdade de Ciências, Portugal
	Universidade do Porto Faculdade de Ciências, Portugal
2023/03/01 - 2023/06/30	Researcher (Research)	Universidade do Porto Faculdade de Ciências, Portugal
	Universidade do Porto Faculdade de Ciências, Portugal
2021/02/01 - 2023/01/31	Researcher (Research)	Universidade do Porto Faculdade de Ciências, Portugal
	Universidade do Porto Faculdade de Ciências, Portugal
2014/08/01 - 2014/12/20	Researcher (Research)	Conselho Nacional de Desenvolvimento Científico e Tecnológico, Brazil
	Instituto de Química da Universidade Estadual de Campinas , Brazil
2013/02/01 - 2014/07/31	Researcher (Research)	Conselho Nacional de Desenvolvimento Científico e Tecnológico, Brazil
	Universidade Estadual de Campinas Instituto de Química, Brazil
2008/10/01 - 2009/04/30	Researcher (Research)	Fundação de Amparo à Pesquisa do Estado de São Paulo, Brazil
	Universidade Estadual de Campinas Instituto de Química, Brazil

Positions / Appointments

	Category Host institution	Employer
2017/03/01 - 2019/07/31	Pesquisador de Tecnologia Analítica	EMS, Brazil
	EMS, Brazil
2016/05/01 - 2017/12/31	Estágiário Químico	Merck Sharp & Dohme, Brazil
	Merck Sharp & Dohme, Brazil
2014/12/27 - 2016/03/15	Au Pair	Au Pair in América , United States
	Au Pair in América , United States
2010/05/01 - 2013/02/28	Técnico de Laboratório	Faculdade de Ciências Aplicadas da Unicamp, Brazil
	Faculdade de Ciências Aplicadas da Unicamp, Brazil

Projects

Grant

	Designation	Funders
2023/10/01 - Current	Development of natural-based nanostructured lipid carriers for controlled drug delivery and treatment of myocardial infarction 2023.00580.BD PhD Student Fellow
2023/03/01 - Current	GreenShoes 4.0 POCI-01-0247-FEDER-046082 Research Fellow Universidade do Porto Faculdade de Ciências, Portugal	European Regional Development Fund
2021/02/01 - 2023/01/31	SYLC .: Development of a CCD detector for Liquid Chromatography NORTE-01-0247-FEDER-045394 Research Fellow Universidade do Porto Faculdade de Ciências, Portugal	Universidade do Porto Faculdade de Ciências Concluded
2014/08/01 - 2014/12/20	3-[[4´-(phenylmethoxy)phenyl]methoxy]-1-azabicyclo[2.2.2.]octane Chirals as Inhibitors of Pathogenic Tropical Protozoa and Fungi 119270/2014-5 Scientific Initiation Fellow Instituto de Química da Universidade Estadual de Campinas , Brazil	Conselho Nacional de Desenvolvimento Científico e Tecnológico Concluded
2013/02/01 - 2014/07/31	3-[[4´-(phenylmethoxy)phenyl]methoxy]-1-azabicyclo[2.2.2.]octane Chirals as Inhibitors of Pathogenic Tropical Protozoa and Fungi 146483/2013-8 Scientific Initiation Fellow Instituto de Química da Universidade Estadual de Campinas , Brazil	Conselho Nacional de Desenvolvimento Científico e Tecnológico Concluded
2008/10/01 - 2009/04/30	Study of protein stability, structure and folding pathway 08/09411-5 Research Technician Fellow Instituto de Química da Universidade Estadual de Campinas , Brazil	Fundação de Amparo à Pesquisa do Estado de São Paulo Concluded

Contract

	Designation	Funders
2023/07/15 - 2023/09/30	BioShoes4All PRR-TC-C12-i01 Research Fellow	Ongoing

Outputs

Publications

Conference poster

RONCAGLIA DOS SANTOS, MAYARA; BERNHARD CAMMERER, SIMON. "3-[[4´-(phenylmethoxy)phenyl]methoxy]-1-azabicyclo[2.2.2.]octane Chirals as Inhibitors of Pathogenic Tropical Protozoa and Fungi". Paper presented in XXIV Congressos de Iniciação Científica, 2016.
RONCAGLIA DOS SANTOS, MAYARA; BERNHARD CAMMERER, SIMON. "3-[[4´-(phenylmethoxy)phenyl]methoxy]-1-azabicyclo[2.2.2.]octane Chirals as Inhibitors of Pathogenic Tropical Protozoa and Fungi". Paper presented in XXII Congresso de Iniciação Científica da Unicamp, 2014.

Journal article

Roncaglia dos Santos, Mayara; Tatiana Andreani; Ruoyu Cheng; Khalil Elbadri; Claudio Ferro; Thacilla Menezes; Carlos M. Pereira; Hélder A. Santos. "Natural compounds-based nanomedicines for cancer treatment: Future directions and challenges". Drug Delivery and Translational Research (2024): http://dx.doi.org/10.1007/s13346-024-01649-z.
10.1007/s13346-024-01649-z
Catarina Ganilho; Márcia Bessa da Silva; Cristiana Paiva; Thacilla Ingrid de Menezes; Mayara Roncaglia dos Santos; Carlos M. Pereira; Ruth Pereira; Tatiana Andreani. "Environmental Safety Assessments of Lipid Nanoparticles Loaded with Lambda-Cyhalothrin". Nanomaterials 12 15 (2022): 2576-2576. https://doi.org/10.3390/nano12152576.
10.3390/nano12152576
de Macedo-Silva, Sara Teixeira; Visbal, Gonzalo; Souza, Gabrielle Frizzo; Santos, Mayara; Cämmerer, Simon B.; de Souza, Wanderley; Rodrigues, Juliany Cola Fernandes. "Benzylamines as highly potent inhibitors of the sterol biosynthesis pathway in Leishmania amazonensis leading to oxidative stress and ultrastructural alterations". Scientific Reports 12 1 (2022): 1-18. http://dx.doi.org/10.1038/s41598-022-15449-3.
Open access • Published • 10.1038/s41598-022-15449-3
de Souza, B F; RONCAGLIA DOS SANTOS, MAYARA; Renan Pimentel de Souza; BERNHARD CAMMERER, SIMON; Natália Aimée d´Angelo; Caio Haddad Franco; Carolina Borsoi Moraes; Lúcio H. Freitas-Junior. "Synthesis of Chiral 3-[[(Aryl) methyl] amino]- and 3-[[(Heteroaryl)-methyl]-amino]- quinuclidines with High Biological Activity against Intracellular Trypansoma cruzi Amastigotes". International Journal of Chemistry and Pharmaceutical Sciences 4 5 (2016): 272-278. https://www.pharmaresearchlibrary.com/wp-content/uploads/2016/07/IJCPS2952.pdf.
Published

Activities

Oral presentation

	Presentation title	Event name Host (Event location)
2022/05/04	Nanotechnology in agriculture: the development of insecticides formulations considering safetyby-design concept	43 / 5,000 Young Research at the University of Porto

Event participation

	Activity description Type of event	Event name Institution / Organization
2016/10/10 - 2016/10/13	XXIV Unicamp Scientific Initiation Congress - To disseminate the results of Scientific and Technological Initiation projects carried out by undergraduate students from Unicamp, as well as from other institutions Congress	XXIV Unicamp Scientific Initiation Congress Universidade Estadual de Campinas, Brazil
2014/08/01 - 2014/08/03	XXII Unicamp Scientific Initiation Congress - To disseminate the results of Scientific and Technological Initiation projects carried out by undergraduate students from Unicamp, as well as from other institutions. Congress	XXIV Unicamp Scientific Initiation Congress Universidade Estadual de Campinas, Brazil
2013/08/01 - 2013/08/07	XII Chemistry Week - is an event that provides diverse content related to the fields and areas of activity of the chemistry professional, complementing the professional training of students. Meeting	XII Chemistry Week Instituto de Química da Universidade Estadual de Campinas , Brazil
2012/08/01 - 2012/08/07	XI Chemistry Week - is an event that provides diverse content related to the fields and areas of activity of the chemistry professional, complementing the professional training of students. Meeting	XI Chemistry Week Instituto de Química da Universidade Estadual de Campinas , Brazil
2012/07/01 - 2012/07/07	Green Chemistry - Meeting of experts from different areas and interdisciplinary reflection on bio-renewables, bioenergy, agroindustry, health, food, the use of by-products or waste, process scaling, official R&D programs in green chemistry, among others, and providing undergraduate students with an overview of Green Chemistry and its importance in solving environmental problems. Meeting	Green Chemistry Universidade de São Paulo, Brazil
2011/08/01 - 2011/08/07	X Chemistry Week - is an event that provides diverse content related to the fields and areas of activity of chemistry professionals, complementing the professional training of students. Meeting	X Chemistry Week Instituto de Química da Universidade Estadual de Campinas , Brazil

Committee member

	Activity description Role	Institution / Organization
2010/05/01 - 2013/01/31	Internal Accident Prevention Committee (CIPA) - with the aim of preventing accidents and illnesses arising from work, in order to permanently make work compatible with the preservation of life and the promotion of worker health. Member	Faculdade de Ciências Aplicadas da Unicamp, Brazil
2010/05/01 - 2013/01/31	Firefighting Brigade - act in situations such as fires and provide assistance when fainting occurs or other situations involving the need for first aid. Member	Faculdade de Ciências Aplicadas da Unicamp, Brazil
2010/05/01 - 2013/01/31	Social Benefits Management Group - working group appointed by the UNICAMP Rectorate to reassess the various programs and actions relevant to the scope of the so-called Spontaneous Benefits Coordinator	Universidade Estadual de Campinas, Brazil