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Sónia Pedro has completed her Bachelor and Master degree in Biochemistry in the University of Aveiro, where is at the moment a PhD student in the Biochemistry filed. Her domain of specialization in the Master degree, Clinical Biochemistry, provided her an advanced training in the field of health sciences, with special emphasis on laboratory diagnosis and study of the molecular mechanisms underlying the disease, knowledge of the determination of biochemical and physiological parameters and its application to the diagnosis, treatment, monitoring or prevention of diseases. Her current research interests are focused on: purification and quantification of cancer biomarkers; clinical diagnosis; prevention and treatment of diseases; study and development of novel drug delivery systems; preparation and characterization of DES comprising active pharmaceutical ingredients; incorporation of novel formulations of DES comprising active pharmaceutical ingredients into biopolymer-based drug delivery systems, which may ultimately stand out as effective treatment options for a widespread number of biomedical applications and biomaterials characterization. Presents other professional interests/competences, like: knowledge in laboratorial diagnosis techniques; determination techniques of biochemical parameters; biological human sample manipulation; competences in several distinct quantification methods, like spectrophotometric quantification assays for proteins and sugars, immunoassay (Blitz) and molecular methods like PCR; experience in the use of SDS-PAGE, UV spectrophotometer and liquid chromatography (HPLC) equipment; experience in liquid-liquid extraction with Aqueous Biphasic Systems (ABS), handling and use of ionic liquids; experience in preparation of deep eutectic solvents and characterization; experience in nuclear magnetic resonance (NMR), thermal gravimetric analysis (TGA) and differential scanning calorimetry (DSC) interpretation data.
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Identification

Personal identification

Full name
Sónia Pedro

Citation names

  • Pedro, Sónia N.

Author identifiers

Ciência ID
7517-9F6D-0036
ORCID iD
0000-0001-9483-0686

Knowledge fields

  • Natural sciences - Biological Sciences - Biochemistry

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
English Intermediate (B1) Advanced (C1) Upper intermediate (B2) Upper intermediate (B2)
Education
Degree Classification
2017/10/01 - 2021/10/01
Ongoing
 Bioquímica (Doutoramento)
Major in PhD student
Universidade de Aveiro, Portugal
2016/10/06 - 2016/10/11
Concluded
 Molecular Medicine International Advanced Training School 2016- Molecular Immunology. (Especialização pós-licenciatura)
Major in Professional Formation
Universidade de Aveiro, Portugal
 9/10
2016
Concluded
 Biochemistry (Mestrado)
Universidade de Aveiro, Portugal
"Concentration and purification of prostate cancer biomarkers envisaging an early diagnosis" (THESIS/DISSERTATION)
 17
2014
Concluded
 Biochemistry (Licenciatura)
Universidade de Aveiro, Portugal
"Concentration of a prostate cancer biomarker using aqueous biphasic systems" (THESIS/DISSERTATION)
 15
Affiliation

Others

Category
Host institution 		Employer
2017/10/01 - 2021/10/01 PhD student Universidade de Aveiro CICECO, Portugal
2016/07/01 - 2017/03/01 Voluntary Investigator in PATh (Process and Product Applied Thermodynamics) research group, in the development of plataforms of precipitation of albumin from human serum Universidade de Aveiro CICECO, Portugal
Universidade de Aveiro, Portugal
2010/08/30 - 2010/09/04 Internship in the School of Life and Health Sciences of of initiation to scientific research. Introduction to microbiology principles and disease screening through biological fluids sample analysis. Universidade do Porto Faculdade de Farmácia, Portugal
Projects

Other

Designation Funders
2019/11/12 - 2019/11/18 API-DES: improving drug solubility with deep eutectic solvents by inelastic neutron scattering
SFRH/BD/132584/2017
1920244
PhD Student Fellow
Rutherford Appleton Laboratory, United Kingdom
Concluded
Outputs

Publications

Conference poster
  1. Pedro, Sónia N.; Valente, Bruno F. A. ; Vilela, Carla; Oliveira, Helena; Almeida, Adelaide; Freire, Mara G.; Silvestre, Armando J. D.; Freire, Carmen S. R.. "Adhesive pullulan-based films comprising deep eutectic-curcumin formulations to overcome antimicrobial multi-resistance". Paper presented in Jornadas CICECO 2022, 2022.
  2. Vieira, Cátia; Pedro, Sónia N.; Mesquita, Mariana Q.; Bartolomeu, Maria; Gomes, Ana T. P. C.; Freire, Carmen S. R.; Ramos, Paula; et al. "Antimicrobial Photodynamic Therapy as an innovative approach for the inactivation of pathogenic bacteria on fish fillet". Paper presented in VI PhD Students Meeting in Environment and Agriculture, 2021.
  3. Vieira, Cátia; Pedro, Sónia N.; Mesquita, Mariana Q.; Gomes, Ana T. P. C.; Freire, Carmen S. R.; Ramos, Paula; Neves, M. Graça P. M. S.; Faustino, M. Amparo F.; Almeida, Adelaide. "Antimicrobial Photodynamic Therapy as an innovative approach to inactivate Escherichia coli on Sea Bass Fillets". Paper presented in 3rd Online International Conference on Aquaculture and Fisheries, 2021.
  4. Pedro, Sónia N.; Freire, Mara G.; Silvestre, Armando J. D.; Freire, Carmen S. R.. Corresponding author: Pedro, Sónia N.. "Deep eutectic solvents as new tools to fight bacterial resistance to antibiotics". Paper presented in Jornadas CICECO 2021, 2021.
  5. Pedro, Sónia N.; Freire, Mara G.; Silvestre, Armando J. D.; Freire, Carmen S. R.. "Boosting the therapeutic efficiency of antibiotics with novel formulations based on deep eutectic solvents". Paper presented in Jornadas CICECO 2020, 2020.
  6. Pedro, Sónia N.; Freire, Mara G.; Silvestre, Armando J. D.; Freire, Carmen S. R.. "Therapeutic formulations based on deep eutectic solvents as new strategies to tackle Pseudomonas aeruginosa infections". Paper presented in Jornadas CICECO 2019, 2019.
  7. Pedro, Sónia N.; Quental, Maria V.; Pereira, Matheus M.; Ferreira, Ana M.; Shahriari, Shahla; Mohamadou, Aminou; Coutinho, João A. P.; Freire, Mara G.. "Ionic Liquid and Carbohydrates based systems as novel sustainable separation platforms.". Paper presented in 13th International Chemical and Biological Engineering Conference, CHEMPOR 2018, 2018.
  8. Pedro, Sónia N.; Freire, Mara G.; Silvestre, Armando J. D.; Freire, Carmen S. R.. "Deep eutectic solvents as active pharmaceutical ingredients- novel liquid formulations for cell therapy". Paper presented in 12th Symposium of the European Society of Biochemical Engineering Sciences, 2018.
  9. Pedro, Sónia N.; Pereira, Matheus M.; Quental, Maria V.; Mohamadou, Aminou; Coutinho, João A. P.; Freire, Mara G.. "Isolation and recovery of proteins from honey samples in a single-step using systems formed by ionic liquids". Paper presented in 12th Symposium of the European Society of Biochemical Engineering Sciences, 2018.
  10. Pedro, Sónia N.; Quental, Maria V.; Ferreira, Ana M.; Shahriari, Shahla; Mohamadou, Aminou; Coutinho, João A. P.; Freire, Mara G.. "Sustainable Separation Plataforms based on Aqueous Biphasic Systems formed by Ionic Liquid and Carbohydrates". Paper presented in 6th Portuguese Young Chemists Meeting, PyChem, 2018.
  11. Pedro, Sónia N.; Pereira, Matheus M.; Lima, Álvaro S.; Coutinho, João A. P.; Freire, Mara G.. "Single-step pretreatment of human serum samples for clinical analysis". Paper presented in XIX National Congress of Biochemistry, 2016.
  12. Pedro, Sónia N.; Pereira, Matheus M.; Lima, Álvaro S.; Coutinho, João A. P.; Freire, Mara G.. "Concentration and purification of cancer biomarkers from human serum using aqueous biphasic systems formed by ionic liquids". Paper presented in XIX National Congress of Biochemistry, 2016.
  13. Pereira, Matheus M.; Pedro, Sónia N.; Lima, Álvaro S.; Coutinho, João A.P.; Freire, Mara G.. "Development of alternative early-stage cancer diagnosis methods by the application of ionic liquids". Paper presented in PATh Spring Workshop, 2016.
  14. Pereira, Matheus M.; Pedro, Sónia N.; Quental, Maria V.; Lima, Álvaro S.; Coutinho, João A. P.; Freire, Mara G.. "Extraction of bovine serum albumin with aqueous biphasic systems formed by phosphonium- and ammonium-based ionic liquids". Paper presented in Biopartitioning and Purification Conference, 2015.
  15. Pedro, Sónia N.; Pereira, Matheus M.; Lima, Álvaro S.; Coutinho, João A. P.; Freire, Mara G.. "New strategy for an early-stage cancer diagnosis by the concentration of lactate dehydrogenase (LDH) using ionic liquid- based systems". Paper presented in Biopartitioning and Purification Conference, 2015.
  16. Pereira, Matheus M.; Pedro, Sónia N.; Lima, Álvaro S.; Coutinho, João A. P.; Freire, Mara G.. "Attempt of an early diagnosis by the concentration of lactate dehydrogenase (LDH) using ionic liquid-based systems". Paper presented in 1st ASPIC International Congress, 2014.
Journal article
  1. Sónia N. Pedro; Bruno F.A. Valente; Carla Vilela; Helena Oliveira; Adelaide Almeida; Mara G. Freire; Armando J.D. Silvestre; Carmen S.R. Freire. "Switchable adhesive films of pullulan loaded with a deep eutectic solvent-curcumin formulation for the photodynamic treatment of drug-resistant skin infections". Materials Today Bio (2023): https://doi.org/10.1016/j.mtbio.2023.100733.
    10.1016/j.mtbio.2023.100733
  2. Matheus M. Pereira; Sónia N. Pedro; Maria V. Quental; Aminou Mohamadou; João A. P. Coutinho; Mara G. Freire. "Integrated Approach to Extract and Purify Proteins from Honey by Ionic Liquid-Based Three-Phase Partitioning, selected cover of the issue 29 of the journal ACS Sustainable Chemistry & Engineering". ACS Sustainable Chemistry & Engineering 10 29 (2022): 9275-9281. http://dx.doi.org/10.1021/acssuschemeng.2c01782.
    10.1021/acssuschemeng.2c01782
  3. Sónia N. Pedro; Maria S. M. Mendes; Bruno M. Neves; Isabel Filipa Almeida; Paulo Costa; Inês Correia-Sá; Carla Vilela; et al. "Deep Eutectic Solvent Formulations and Alginate-Based Hydrogels as a New Partnership for the Transdermal Administration of Anti-Inflammatory Drugs". Pharmaceutics 14 4 (2022): 827-827. https://doi.org/10.3390/pharmaceutics14040827.
    10.3390/pharmaceutics14040827
  4. Sónia N. Pedro; Mariela M. Nolasco; Carla Vilela; Pedro D. Vaz; Paulo Ribeiro-Claro; Svemir Rudic; Stewart F. Parker; et al. "Water in Deep Eutectic Solvents: New Insights From Inelastic Neutron Scattering Spectroscopy". Frontiers in Physics 10 (2022): http://dx.doi.org/10.3389/fphy.2022.834571.
    10.3389/fphy.2022.834571
  5. Sónia N. Pedro; Carmen S. R. Freire; Armando J. D. Silvestre; Mara G. Freire. "Deep Eutectic Solvents and Pharmaceuticals". Encyclopedia 1 3 (2021): 942-963. https://doi.org/10.3390/encyclopedia1030072.
    10.3390/encyclopedia1030072
  6. Sónia N. Pedro; Carmen S. R. Freire; Armando J. D. Silvestre; Mara G. Freire. "Ionic Liquids in Drug Delivery". Encyclopedia 1 2 (2021): 324-339. https://doi.org/10.3390/encyclopedia1020027.
    10.3390/encyclopedia1020027
  7. Pedro, Sónia N.; R. Freire, Carmen S.; Silvestre, Armando J. D.; Freire, Mara G.. "The Role of Ionic Liquids in the Pharmaceutical Field: An Overview of Relevant Applications". International Journal of Molecular Sciences 21 21 (2020): 8298. http://dx.doi.org/10.3390/ijms21218298.
    10.3390/ijms21218298
  8. Pereira, Matheus M.; Pedro, Sónia N.; Gomes, Joana; Sintra, Tânia E.; Ventura, Sónia P.M.; Coutinho, João A.P.; Freire, Mara G.; Mohamadou, Aminou. "Synthesis and characterization of analogues of glycine-betaine ionic liquids and their use in the formation of aqueous biphasic systems". Fluid Phase Equilibria 494 (2019): 239-245. http://dx.doi.org/10.1016/j.fluid.2019.05.001.
    10.1016/j.fluid.2019.05.001
  9. Pedro, Sónia N.; Freire, Mara G.; Freire, Carmen S. R.; Silvestre, Armando J. D.. "Deep eutectic solvents comprising active pharmaceutical ingredients in the development of drug delivery systems". Expert Opinion on Drug Delivery 16 5 (2019): 497-506. http://dx.doi.org/10.1080/17425247.2019.1604680.
    10.1080/17425247.2019.1604680
  10. Quental, Maria V.; Pereira, Matheus M.; Ferreira, Ana M.; Pedro, Sónia N.; Shahriari, Shahla; Mohamadou, Aminou; Coutinho, João A. P.; Freire, Mara G.. "Enhanced separation performance of aqueous biphasic systems formed by carbohydrates and tetraalkylphosphonium- or tetraalkylammonium-based ionic liquids". Green Chemistry 20 13 (2018): 2978-2983. http://dx.doi.org/10.1039/c8gc00622a.
    10.1039/c8gc00622a
  11. Pereira, Matheus M.; Pedro, Sónia N.; Quental, Maria V.; Lima, Álvaro S.; Coutinho, João A.P.; Freire, Mara G.. "Enhanced extraction of bovine serum albumin with aqueous biphasic systems of phosphonium- and ammonium-based ionic liquids". Journal of Biotechnology 206 (2015): 17-25. http://dx.doi.org/10.1016/j.jbiotec.2015.03.028.
    10.1016/j.jbiotec.2015.03.028
Thesis / Dissertation
  1. Pedro, Sónia. "Concentration and purification of prostate cancer biomarkers envisaging an early diagnosis". Master, Universidade de Aveiro, 2016.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2022/07/14 Deep eutectic solvents comprising active pharmaceutical ingredients for incorporation in biopolymer-based drug delivery systems Research Summit 2022
University of Aveiro (Aveiro, Portugal)
2022/06/02 The successful partnership between deep eutectic solvent formulations and biopolymers in the transdermal delivery of NSAIDs PATh/IL2BioPro/mVACCIL workshop
University of Aveiro (Aveiro, Portugal)
2021/06/15 Delivery of Deep Eutectic Solvents Comprising Nonsteroidal Anti-inflammatory Drugs using Biopolymer-Based Systems 2nd International Meeting on Deep Eutectic Solvents
Faculdade de Ciências e Tecnologia Universidade Nova de Lisboa (Lisboa)
2020/07/30 Deep eutectic solvents comprising active pharmaceutical ingredients, searching new therapeutic approaches International (online) Workshop on Deep Eutectic Solvents for Environmental Remediation and Energy Storage
Department of Chemical Engineering, IIT Guwahati (India)
2020/06/25 Deep eutectic solvents comprising active pharmaceutical ingredients for incorporation in biopolymer-based drug delivery systems Research Summit 2020
University of Aveiro (Aveiro, Portugal)
2019/07/05 Deep eutectic solventes comprising active pharmaceutical ingredientes for incorporation in biopolymer-based drug delivery systems Research Summit
University of Aveiro (Portugal)
2019/06/24 Eutectic Solvents Comprising Antibiotics - A Breakthrough In Topical Treatment 1st International Meeting on Deep Eutectic Solvents
Universidade Nova de Lisboa (Lisboa, Portugal)
2019/05/13 Deep eutectic solvents comprising active pharmaceutical ingredients- antibiotic-based liquid formulations for drug delivery ISGC 2019
La Rochelle (La Rochelle, France)
2019/04/11 Eutectic solvents comprising active pharmaceutical ingredients, an improvement in therapeutics Path Workshop
University of Aveiro (Aveiro, Portugal)
2018/06/12 Fractionation of value-added compounds from honey using ionic-liquid-based systems Path Spring Workshop
CICECO (Aveiro, Portugal)
2017/11/22 Isolation and recovery of proteins from honey samples using aqueous biphasic systems formed by ionic liquids and carbohydrates Anything But Conventional Chromatography (ABC2)
Downstream Processing group of ESBES (Lisboa, Portugal)
2017/03/30 Synthesis of glycine-betaine-based-ionic liquids for the development of novel strategies regarding the purification of added-value proteins EXIL Workshop - Liquid/liquid extraction with Ionic Liquids
Lyon (Lyon, France)
2016/05/17 Early-stage cancer diagnosis by the extraction of lactate dehydrogenase (LDH) from human serum using ionic-liquidbased systems Emerging Trends in Separation Science and Technology, SESTEC 2016
Guwahati (Guwahati, India)
2016/04/26 Development of alternative early-stage cancer methods by the application of ionic liquids PATh Spring Workshop
CICECO (Aveiro, Portugal)
2015/09/01 Extração de albumina de soro bovino utilizando sistemas aquosos bifásicos compostos por líquidos iónicos e sal XX Simpósio Nacional de Bioprocessos
Fortaleza (Fortaleza, Brazil)

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2020/11/19 - 2020/11/20 CICECO CAD Meeting 2020- a satellite event organized by the PhD students council (CAD) within Jornadas CICECO 2020 (2020/11/19 - 2020/11/20)
Meeting (Member of the Organising Committee)
 Universidade de Aveiro, Portugal
2020/10/19 - 2020/10/19 Stylish Academic Writing- The first event within the scope of WritingLeague@UA with participation of the internationally recognized Profª. Helen Sword (2020/10/19 - 2020/10/19)
Seminar (Member of the Organising Committee)
 Universidade de Aveiro, Portugal
2020/02/12 - 2020/02/12 1st AIM Further was a whole day meeting event made only for PhD students to share ideas, learn about new topics, discuss important issues related with writing a thesis and working as a PhD student, but also to promote communication within the institute and team building activities. This event took place at PCI - Creative Science Park at February 12th of 2020. (2020/02/12 - 2020/02/12)
Meeting (Member of the Organising Committee)
 Universidade de Aveiro, Portugal
2015/03/27 - 2015/03/29 III National Meeting of Chemistry Students (ENEQUI), with special participation of the internationally known Professor Peter Atkins (2015/03/27 - 2015/03/29)
Meeting (Member of the Organising Committee)
 Universidade de Aveiro, Portugal

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2014/10/19 - Current Lecture of Dr Ronald DePinho
Seminar
 Making cancer history together
Universidade de Aveiro, Portugal
2021/10/04 - 2021/12/13 Program designed for young graduate and senior students, along with technical personnel and professors, who want to gain in-depth knowledge of nanotechnology to develop new biomedical and pharmaceutical systems or found technology-based startup companies. Speakers: Professor Nicholas Peppas (the University of Texas at Austin, USA)
Workshop
 Interdisciplinary Training Program on Principles, Applications and Nanotechnology Innovation in Pharmaceutical Sciences, Biological Engineering and Medicine.
Associação para a Inovação e Desenvolvimento da FCT, Portugal

The University of Texas at Austin, United States
2020/09/21 - 2020/09/21 A Technological Perspective on Cancer: from Diagnosis and Treatment to Environmental Fate and Remediation
Workshop
 PATh/IonCytDevice Workshop
Universidade de Aveiro, Portugal
2018/10/11 - 2018/10/13 Presenting the MultiBiorrefinery stand in the Aveiro Forum of innovation and technology
Exhibition
 TechDays 2018- Aveiro
Câmara Municipal de Aveiro, Portugal

Association member

Society Organization name Role
2020/05/01 - 2021/03/01 WrtitingLeague@UA- the first group of scientific and creative writing in University of Aveiro Organization member
2019/05/01 - 2020/12/31 PhD Students Council (CAD) of CICECO, Aveiro Institute of Materials, University of Aveiro Co-founder and member
2014/01/01 - 2014/12/31 University of Aveiro Chemistry Students Union (NEQ-AAUAv) Member of the board, responsible for scientific divulgation
Distinctions

Award

2022 Best Poster (Jornadas CICECO 2022) - Adhesive pullulan-based films comprising deep eutectic-curcumin formulations to overcome antimicrobial multi-resistance
Universidade de Aveiro CICECO, Portugal
2022 Best communication award (Research Summit UA)- Deep eutectic solventes comprising active pharmaceutical ingredientes for incorporation in biopolymer-based drug delivery systems
Universidade de Aveiro, Portugal
2022 Best communication award - PATh/IL2BioPro/mVACCIL workshop
Universidade de Aveiro, Portugal
2021 2nd Place- Best PhD video
Universidade de Aveiro CICECO, Portugal
2021 Best photo in materials@AVEIRO Award
Universidade de Aveiro CICECO, Portugal
2019 Poster award (Jornadas CICECO 2019)- Therapeutic formulations based on deep eutectic solvents as new strategies to tackle Pseudomonas aeruginosa infections
Universidade de Aveiro CICECO, Portugal
2019 Best communication award (Research Summit UA)- Deep eutectic solventes comprising active pharmaceutical ingredientes for incorporation in biopolymer-based drug delivery systems
Universidade de Aveiro, Portugal

Other distinction

2022 Selected cover of the issue 29 of the journal ACS Sustainable Chemistry & Engineering
2022 Highly Cited Papers of IJMS in 2020 - "The Role of Ionic Liquids in the Pharmaceutical Field: An Overview of Relevant Applications"
2017 Winner of the José Luís Peixoto Literary Prize (prose modality)
2015 Winner of the José Luís Peixoto Literary Prize (prose modality)
2013 Honorable mention- José Luís Peixoto Literary Prize (prose modality)
2010 Merit framework of academic year 2010/2011