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Victoria Leiro got her PhD in Organic Chemistry from the University of Santiago de Compostela (Spain), in December 2007. Even before her PhD defense, she was hired in the context of a CENIT program (2006-2010) of the Spanish “Centro para el Desarrollo Tecnológico Industrial”, which was launched to stimulate the public–private cooperation in industrial research. The project, carried out in collaboration with the Spanish company of biotechnology Pharmamar S.A., consisted of the synthesis of dendrimers for delivery of anticarcinogenic drugs. Since 2011, she is a researcher (FCT BPD 2010 post-doctoral grant; contracted Researcher since 2017; Assistant Researcher since 2022) in the nBTT-nanoBiomaterials for Targeted Therapies Group at i3S-Instituto de Investigação e Inovação em Saúde and INEB-Instituto de Engenharia Biomédica (Porto, Portugal). In the highly competitive 2021 Individual Call to Scientific Employment Stimulus from FCT, Leiro was granted with a contract to work as an Assistant Researcher at i3S. Her research is focused on the development of new biodegradable nanobiomaterials (biodegradable dendrimers), as well as their application as vectors of different therapeutic nucleic acids and drugs, and bioimaging agents for different neuro-applications. Recently, she is also exploring these dendrimers as nucleic acid vectors targeted to the cartilaginous tissue of the joint and intervertebral disc; and also as vectors of therapeutics for cancer treatment in a collaboration with a biopharmaceutical company. Additionally, the development, functionalization, characterization and biological evaluation of different biomaterials of great interest for several biomedical applications (including biomaterials with antimicrobial properties or for use in regenerative medicine) are also among her research interests. Victoria Leiro has participated in 18 research projects. Her scientific production includes 25 documents: 22 articles in peer reviewed international journals (100% in Q1; 12 as first author; 5 as corresponding senior author), 2 book chapters and has 1 patent registered, already granted in US, and licensed to a pharma company. VL has received 20 awards and/or honors. She is co-supervising 3 PhD theses, supervised 12 MSc theses, 1 undergraduate internship, 8 MSc Research Assistants, and she was mentor of more than 30 students. She is a referee for international peer-reviewed journals. VL has participated in numerous conferences (2 keynote, 6 invited talk, 48 oral communications and 77 posters), numerous workshops, advanced courses, and in activities of scientific outreach (Universidade de Santiago de Compostela and Universidade do Porto). She is member of the European Society for Biomaterials and Galician Nanomedicine Network.
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Identification

Personal identification

Full name
Victoria Leiro
Gender
Female

Citation names

  • Leiro, V
  • Victoria Leiro
  • Leiro, Victoria
  • V Leiro
  • Victoria Rodriguez
  • Rodriguez, Victoria
  • Rodriguez, V

Author identifiers

Ciência ID
7713-0BE4-AC65
ORCID iD
0000-0002-8907-9151

Email addresses

  • victoria.leiro@ineb.up.pt (Professional)
  • victoria.leiro@i3s.up.pt (Professional)
  • vicky.leiro@gmail.com (Personal)

Telephones

Telephone
  • 220408800 (Professional)

Addresses

  • INEB-Instituto de Engenharia Biomédica & i3S-Instituto de Investigação e Inovação em Saúde. Universidade do Porto. Rua Alfredo Allen, 208, 4200-135, Porto, Porto, Portugal (Professional)

Websites

  • orcid.org/0000-0002-8907-9151; http://www.ineb.up.pt; http://www.i3s.up.pt/ (Professional)

Knowledge fields

  • Exact Sciences - Chemical Sciences
  • Exact Sciences - Chemical Sciences - Organic Chemistry
  • Exact Sciences - Chemical Sciences - Polymer Science
  • Medical and Health Sciences - Medical Biotechnology - Biomaterials
  • Medical and Health Sciences - Medical Biotechnology - Gene-based Diagnostics and Therapeutic Interventions
  • Medical and Health Sciences - Medical Biotechnology - Technologies Involving the Manipulation of Cells, Tissues, Organs or the Whole Organism

Languages

Language Speaking Reading Writing Listening Peer-review
Spanish; Castilian (Mother tongue)
Galician (Mother tongue)
Portuguese Advanced (C1) Proficiency (C2) Proficiency (C2) Proficiency (C2) Advanced (C1)
English Upper intermediate (B2) Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Education
Degree Classification
2003 - 2007
Concluded
 PhD in Organic Chemistry (Doutoramento)
Universidad de Santiago de Compostela Departamento de Química Orgánica, Spain
""Determinación de la configuración absoluta de aminoalcoholes por RMN"" (THESIS/DISSERTATION)
 Outstanding with distinction (Excelente com distin
2002 - 2004
Concluded
 Master (Diploma de Estudios Avanzados (DEA)) (Mestrado)
Universidad de Santiago de Compostela Departamento de Química Orgánica, Spain
""Determinación de la configuración absoluta de 1,2- aminoalcoholes por RMN"" (THESIS/DISSERTATION)
 20/20 (Portugal); 10/10 (Spain)
2002 - 2003
Concluded
 "Tesina - Licenciatura con Grado" (Mestrado)
Universidad de Santiago de Compostela Departamento de Química Orgánica, Spain
""Nuevas Metodologías para la Determinación de la Configuración Absoluta de Aminoalcoholes mediante RMN"" (THESIS/DISSERTATION)
 Outstanding with distinction (Excelente com distin
1997 - 2002
Concluded
 Graduation in Chemistry (Pre-Bologna) (Licenciatura)
Universidade de Santiago de Compostela Facultade de Química, Spain
"Chemistry" (THESIS/DISSERTATION)
 19/20 (Portugal); 3.31/4.00 (Spain)
Affiliation

Science

Category
Host institution 		Employer
2022/06/01 - Current Auxiliary Researcher (Research) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2023/05/02 - 2023/05/12 Visiting Researcher (Research) Max Planck Institute for Polymers Research, Germany
Max Planck Institute for Polymers Research, Germany
2022/11/16 - 2022/11/25 Visiting Researcher (Research) Max Planck Institute for Polymers Research, Germany
Max Planck Institute for Polymers Research, Germany
2017/06 - 2022/05/31 Contracted Researcher (Research) Instituto Nacional de Engenharia Biomédica, Portugal
Instituto Nacional de Engenharia Biomédica, Portugal
(...)
2014/04 - 2017/05 Postdoc (Research) Instituto Nacional de Engenharia Biomédica, Portugal
Instituto Nacional de Engenharia Biomédica, Portugal
2011 - 2014 Postdoc (Research) Fundação para a Ciência e a Tecnologia, Portugal
Instituto Nacional de Engenharia Biomédica, Portugal
2007/04 - 2009/12 Postdoc (Research) Spanish Ministry of Industry, Tourism and Commerce CEDTI, Spain
Universidad de Santiago de Compostela Departamento de Química Orgánica, Spain
(...)

Others

Category
Host institution 		Employer
2021/05 - Current Member of the Board of Reviewing Editors of Frontiers in Bioengineering and Biotechnology Frontiers Editorial, Switzerland
2021/04 - Current Member of the Board of Topic Editors of Pharmaceutics MDPI Editorial, Switzerland
2003 - 2007 Ph.D. student Spanish Ministry of Education, Spain
Universidad de Santiago de Compostela Departamento de Química Orgánica, Spain
2002 - 2003 Master Student Government of Galicia (Xunta de Galicia), Spain
Universidad de Santiago de Compostela Departamento de Química Orgánica, Spain
Projects

Grant

Designation Funders
2023 - 2025 DendriFAST - Smart dendritic contrast agent for accurate stroke diagnosis by computed tomography
CI23-10022
Principal investigator
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
 LaCaixa Foundation
Ongoing
2022/01/01 - 2024/12/31 JumpIN - HiJacking the peripheral neurons retrograde trafficking machinery to deliver neUroprotective Molecules to the sPinal cord InterNeuron
PTDC/BTM-MAT/4156/2021
Co-Principal Investigator (Co-PI)
Fundação para a Ciência e a Tecnologia
Ongoing
2021 - 2024 CARTHAGO programme: Cartilaginous tissue regeneration by gene therapy; taking the hurdles towards efficient delivery
860151
 EU Framework Programme for Research and Innovation Marie Sklodowska-Curie Actions
2022/01/01 - 2023/06/30 BioCoat - Engineered biomimetic hydrogel coating for improved biocompatibility of chronically-implanted neural electrodes
EXPL/BTM-MAT/1499/2021
 Fundação para a Ciência e a Tecnologia
2019 - 2021 Engineering Precision Bionanotheranostics. “Cooperação Transnacional” Program FCT-DAAD (Deutscher Akademischer Austauschdienst)
2018 ALEMANHA-DAAD
 Fundação para a Ciência e a Tecnologia
2018 - 2021 iDNArT - Intelligent DNA nanostructures aimed at brain therapeutics
PTDC/NAN-MAT/30898/2017
 Fundação para a Ciência e a Tecnologia
2018 - 2020 PROJECT OF SPECIAL RELEVANCE IN COLLABORATION WITH COMPANIES: siRNAC - Novel siRNA therapies against metastatic colorectal cancer
NORTE-01-0247-FEDER-033399
 Norte2020 Operational Programme

Phyzat Biopharmaceuticals
2016 - 2019 BaiTS - Biodegradable dendrimers for Targeted neuroprotective therapies in Stroke
PTDC/CTM-NAN/3547/2014
Researcher
Fundação para a Ciência e a Tecnologia
2016 - 2018 COMBINE - Combinatorial regenerative strategy to potentiate axon regeneration and improve functional recovery after spinal cord injury. Melo Castro Award 2015. Santa Casa Neurosciences Prizes.
MC-1068-2015
 Santa Casa da Misericórdia de Lisboa
2016 - 2018 NanoProtetor - nanoTerapias neuroprotetoras avançadas para o tratamento de acidentes vasculares cerebrais
. FIS-2015-01_CCV_20150630-88
 Ministério da Saúde

Infarmed Autoridade Nacional do Medicamento e Produtos de Saúde IP
2016/06 - 2017/05 Post-doctoral Researcher
NORTE-01-0145-FEDER-000012
Post-doc Fellow
Instituto Nacional de Engenharia Biomédica, Portugal

Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
INEB - Instituto de Engenharia Biomédica. Project NORTE-01-0145-FEDER-000012, financed by Norte Portugal Regional Operational Programme (NORTE 2020)
2011/04 - 2016/05 Post-doctoral Researcher
SFRH/BPD/69110/2010
Post-doc Fellow
Instituto Nacional de Engenharia Biomédica, Portugal
 Foundation for Science e Technology, Ministry of Science, Technology and Higher Education
2009 - 2012 Polímeros helicoidales: síntesis y aplicaciones como biosensores
CTQ2009-08632/BQU
 Spanish Ministry of Science and Innovation
2009 - 2012 Biosensores para recoñecemento quiral de biomoléculas e fármacos: polímeros helicoidales e nanopartículas
PGIDIT09CSA029209PR
 Government of Galicia (Xunta de Galicia)
2007 - 2009 PROJECT OF SPECIAL RELEVANCE IN COLLABORATION WITH COMPANIES: NANOFARMA - Síntesis de dendrímeros para transporte de fármacos antitumorales.
NANOFARMA_2007_2009
 Spanish Ministry of Industry, Tourism and Commerce CEDTI

Pharmamar S.A.
2006 - 2009 Recoñecemento quiral de compostos polifuncionais
PGIDIT06PXIB209029PR
 Government of Galicia (Xunta de Galicia)
2005 - 2008 La asignación de la configuración absoluta por RMN
CTQ2005-05296/BQU
 Spanish Ministry of Education and Science
2003/03 - 2007/02 Formación de Profesorado Universitario (FPU)
AP2002-0611
PhD Student Fellow
Universidad de Santiago de Compostela Departamento de Química Orgánica, Spain
Concluded
2004 - 2007 Novas estratexias terapéuticas en enfermidades respiratorias: Deseño, Sínteses e caracterización de novos polímeros biocompatibles
PGIDIT04PXIC20903PN
 Government of Galicia (Xunta de Galicia)
2006 - 2006 Ayudas para la adquisición de infraestructuras científico-técnicas y material bibliográfico
PGIDIT06PXIA209021IF
 Government of Galicia (Xunta de Galicia)
2003 - 2006 Recoñecemento de quiralidade por RMN: desenvolvemento de procedementos avanzados e a compostos polifuncionais
PGIDIT03PXIC20908PN
 Government of Galicia (Xunta de Galicia)
2002 - 2003 Master-Scholarship from the Government of Galicia (Xunta de Galicia)
Master-Scholarship
Master Student Fellow
Universidad de Santiago de Compostela Departamento de Química Orgánica, Spain
 Government of Galicia (Xunta de Galicia)
Concluded

Contract

Designation Funders
2022/06/01 - Current CEEC IND4ed- Individual Call to Scientific Employment Stimulus - 4th Edition
2021.00472.CEECIND/CP1663/CT0008
Researcher
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2017/06 - Current Contracted Researcher
i3S.HOST_RL4_ID_01_2017
Instituto Nacional de Engenharia Biomédica, Portugal

Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
INEB - Instituto de Engenharia Biomédica. NORTE-01-0145-FEDER-000012, Structured Programme on Bioengineering Therapies for Infectious Diseases and Tissue Regeneration
Outputs

Publications

Book chapter
  1. Leiro, Victoria; Parreira, Paula; Freitas, Sidónio C.; Martins, Maria Cristina L.; Pêgo, Ana Paula. "Conjugation Chemistry Principles and Surface Functionalization of Nanomaterials". In Biomedical Applications of Functionalized Nanomaterials, 35-66. Elsevier, 2018.
    10.1016/b978-0-323-50878-0.00002-1
  2. Leiro, V.; Moreno, P.M.; Sarmento, B.; Durão, J.; Gales, L.; Pêgo, A.P.; Barrias, C.C.. "Design and preparation of biomimetic and bioinspired materials". In Bioinspired Materials for Medical Applications, 1-44. Elsevier, 2017.
    10.1016/b978-0-08-100741-9.00001-2
Conference abstract
  1. Marília Torrado; Silva, Duarte; Leiro, Victoria; Santos, Sofia Duque; Pêgo, Ana. "The empire strikes back: Biodegradable dendrimers as delivery vectors of neuroprotective therapies for stroke". Paper presented in 10th i3S annual meeting, Póvoa de Varzim, 2023.
  2. Marília Torrado; Santos, Sofia; Leiro, Victoria; Silva, Duarte; Pêgo, Ana. "The ¿shuttles¿ to neuroprotection: Biodegradable dendrimers as delivery vectors in the context of stroke". Paper presented in European Society of Biomaterials 2023, 2023.
  3. Marília Torrado; Leiro, Victoria; Santos, Sofia Duque; Pêgo, Ana Paula. "Biodegradable dendrimers for mRNA therapeutics: crossing the BBB of the ischemic brain". Paper presented in 32nd Annual Conference of the European Society for Biomaterials (ESB2022), Bordeaux, 2022.
  4. Fonseca, Diana R.; Moura, Ana; Teixeira, Catia; Seabra, Catarina Leal; Leiro, Victoria; B. N. Estevinho; Gomes, Paula; Parreira, Paula; Martins, M.Cristina L.. "The bittersweet symphony of Pexiganan-A grafted chitosan microparticles & Helicobacter pylori". Paper presented in Applied Nanotechnology and Nanoscience International Conference 2021, Online, 2021.
    Published
  5. Torrado, M.; Leiro, V; Santos, SDS; Pêgo, A.P. "From bench to ischemic brain: Biodegradable dendrimers as novel tools to be applied as aneuroprotective strategy". Paper presented in 12th FENS Forum ofNeuroscience, Glasgow, 2020.
  6. Leiro, V; Spencer AP; Pêgo AP. "Novel fully biodegradable PEG-dendrimers: Synthesis and function as efficient vehicles of siRNA to neuronal cells". Paper presented in 8th i3S Annual Meeting, Póvoa de Varzim, 2019.
  7. Silva-Reis SC; Mota P; Pêgo A.P; Leiro, V. "Innovative Biodegradable Dendrimers to act as Novel Nanocarriers for Nucleic Acids Delivery – Design and Synthesis Approaches". Paper presented in 8th i3S Annual Meeting, Póvoa de Varzim, 2019.
  8. Mota P; Silva-Reis SC; Pêgo AP; Leiro, V. "Scale-up synthesis of PEG-dendrimers to act as nucleic acids vectors". Paper presented in 8th i3S Annual Meeting, Póvoa de Varzim, 2019.
  9. Spencer AP; Leiro, V; Pêgo AP. "The biological assessment of an innovative family of fully biodegradable dendrimers as siRNA delivery vectors". Paper presented in 8th i3S Annual Meeting, Póvoa de Varzim, 2019.
  10. Santos SD; Bola DC; Teixeira S.; Sousa SS; Leiro, V; Pêgo AP. "Unravelling the potential of chitosanderived nanoparticles for therapeutic synergism in stroke using antagomiR technology and neurotrophin mimetics". Paper presented in 8th i3S Annual Meeting, Póvoa de Varzim, 2019.
  11. Custódio, Beatriz; Magalhães N.; Marques JF; Silva-Reis SC; Mota P; Leiro, V; Bessa J; Santos SD; Pêgo AP. "The blood-brain barrier as a challenge to face in the delivery of nucleic acids mediated by dendrimers in brain ischemia". Paper presented in 8th i3S Annual Meeting, Póvoa de Varzim, 2019.
  12. Fonseca DR; Moura A.; Seabra CL; Leiro, V; Estevinho B; Gomes P.; Parreira P; Martins MCL. "Chitosan microspheres immobilized MSI-78A Antimicrobial Peptidefor Helicobacter pylori Infection Management". Paper presented in 8th i3S Annual Meeting, Póvoa de Varzim, 2019.
  13. Leiro, V; Spencer AP; Magalhães N; Pêgo AP. "A novel family of fully biodegradable PEG-dendrimers as efficient carriers for gene therapy". Paper presented in 30th Annual Conference of the European Society for Biomaterials (ESB2019), Dresden, 2019.
  14. Leiro, V; Santos S.; Spencer AP; Torrado, Marília; Custódio, Beatriz; Magalhães N.; Mota P.; Reis S.; Pêgo AP. "From Peripheral to Central Nervous System: A Journey Towards Targeted Neuronal Delivery". Paper presented in IDS11 - 11th International Dendrimer Symposium. Funchal, Madeira, Portugal., Funchal, Madeira, 2019.
  15. Leiro, V; Spencer AP; Magalhães N.; Pêgo AP. "New fully biodegradable PEG-dendritic block copolymers: from synthesis to application as efficient nanocarriers of siRNA". Paper presented in IDS11 - 11th International Dendrimer Symposium. Funchal, Madeira, Portugal., Funchal, Madeira, 2019.
  16. Spencer, A.P.; Magalhães, N.; Leiro, V; Pêgo, AP. "Innovative fully biodegradable PEG-dendritic block copolymers: biological assessment assiRNA delivery vectors". Paper presented in IDS11 - 11th International Dendrimer Symposium, Funchal, 2019.
  17. Spencer AP; Leiro, V; Pêgo AP. "New Fully Biodegradable Dendrimers as delivery vectors for gene therapy". Paper presented in VII AEICBAS Biomedical Congress, Porto, 2019.
  18. Santos, SDS; Xavier, M.; Leite, DM; Moreira, DA; Custódio, B.; Torrado, M.; Castro, R.; et al. "The transport of therapeutic molecules to the ischemic brain: dendrimers as carriers in pre-clinical studies". Paper presented in XVI Meeting of the Portuguese Society for Neuroscience, Lisbon, 2019.
  19. Torrado, M; Leiro, V; Santos, SDS; Pêgo, AP. "Biodegradable dendrimers as novel tools to deliver neuroprotective nucleic acids in stroke". Paper presented in XVI Meeting of the Portuguese Society for Neuroscience, Lisbon, 2019.
  20. Spencer, A.P.; Leiro, V; Pêgo, AP. "New Fully Biodegradable Dendrimers as nanocarriers for siRNA". Paper presented in 6th IEEE Portuguese Meeting on Bioengineering (ENBENG 2019), Lisbon, 2019.
  21. Spencer AP; Magalhães N.; Leiro, V; Pêgo AP. "New Fully Biodegradable PEG-Dendrimers: Promising non-viral delivery vectors for siRNA delivery". Paper presented in 7th i3S Annual Meeting, Póvoa de Varzim, 2018.
  22. Magalhães N.; Leiro, V; Pêgo AP. "Synthesis and functionalization of PEG-dendrimers". Paper presented in 7th i3S Annual Meeting, Póvoa de Varzim, 2018.
  23. Torrado, Marília; Santos SD; Leiro, V; Pêgo AP. "Biological assessment of biodegradable dendrimers for targeted neuroprotective therapies in stroke". Paper presented in 7th i3S Annual Meeting, Póvoa de Varzim, 2018.
  24. Neto TM; Ferreira-da-Silva F; Leiro, V; Moreno P; Amaral IF. "Development of an injectable self-assembled bioactive hybrid hydrogel". Paper presented in 7th i3S Annual Meeting, Póvoa de Varzim, 2018.
  25. Moura A.; Seabra C; Leiro, V; Estevinho B; Gomes P.; Parreira P; Martins CL. "Antibiotic Free Nano/Microparticles to Fight Helicobacter pylori". Paper presented in 7th i3S Annual Meeting, Póvoa de Varzim, 2018.
  26. Leiro, V; Spencer AP; Magalhães N.; Pêgo AP. "Fully Biodegradable PEG-Dendrimers: Synthesis and “click” functionalization to Act as Nucleic Acid Vectors". Paper presented in 7th i3S Annual Meeting, Póvoa de Varzim, 2018.
  27. Santos SD; Xavier MA; Leite DM; Moreira DA; Custódio, Beatriz; Torrado, Marília; Castro R.; et al. "Blood-Brain Barrier Transport and Neuronal Uptake of PAMAM Dendrimers after Focal Brain Ischemia". Paper presented in 7th i3S Annual Meeting, Póvoa de Varzim, 2018.
  28. Leiro, V; Santos S.; Spencer AP; Magalhães N.; Torrado, Marília; Custódio, Beatriz; Pêgo AP. "Fully biodegradable PEG-dendrimers for nucleic acid delivery". Paper presented in MAD-Nano18 Madeira International Conference, Emerging trends and future of Nanomaterials for Human Health, 2018.
  29. Leiro, V; Spencer AP; Garcia JP; Moreno P.; Pêgo AP. "Fully Biodegradability of PEG-Dendritic Block Copolymers towards an efficient siRNA Delivery". Paper presented in 6th International Symposium on Biomedical Applications of Dendrimers, Urbino, 2018.
  30. Santos, SD; Xavier, M; Leite, DM; Moreira, DA; Castro, R.; Leiro, V; Rodrigues, J; Tomás, H; Pêgo, AP. "Nanoparticle-mediated Blood-Brain Barrier Transport for Neuronal Delivery in Focal Brain Ischemia". Paper presented in 10th International Symposium on Neuroprotection and Neurorepair, Dresden, 2018.
  31. Gomes, CP; Leiro, V; Lopes, CDF; Pêgo, AP. "Fine tuning neuronal targeting of nanoparticles for nucleic acid delivery". Paper presented in 29th Annual Meeting of the European Society for Biomaterials, Maastricht, 2018.
  32. Leiro, V; Spencer, AP; Magalhães, N.; Pêgo, AP; Spencer AP; Magalhães N.; Pêgo AP. "On the Fully Biodegradability of PEG-Dendrimers for siRNA Delivery". Paper presented in 12th International Symposium on Polymer Therapeutics: From Laboratory to Clinical Practice, Valencia, 2018.
  33. Leiro, V; Spencer AP; Magalhães N.; Pêgo AP. "Synthesis and Functionalization of Novel Fully Biodegradable PEG-Dendrimers to Act as Nucleic Acid Vectors". Paper presented in i3S Annual Meeting 2017, Póvoa de Varzim, 2017.
  34. Santos, S.D.; Leiro, V; Lopes C.D.F; Xavier M.A.; Leite D.; Tomás H; Pêgo A.P. "PAMAM dendrimers as delivery vehicle in the injured ischemic brain". Paper presented in i3S Annual Meeting 2017, Póvoa de Varzim, 2017.
  35. Spencer AP; Magalhães N.; Moreno P; Pêgo AP; Leiro, V. "Exploring new fully biodegradable PEG-Dendrimers as siRNA vectors". Paper presented in 6th i3S Annual Meeting, Póvoa de Varzim, 2017.
  36. Leiro, V; Garcia JP; Spencer AP; Moreno P.; Pêgo AP. "Novel biodegradable PEG-dendrimers as vehicles of siRNA". Paper presented in International Symposium on Bioinspired Macromolecular Systems, Aveiro, 2017.
  37. Leiro, V; Garcia JP; Moreno P.; Fernandez-Megia E; Pêgo AP. "Synthesis of biodegradable PEG-GATGE dendritic block copolymers to serve as siRNA vectors". Paper presented in 28th European Conference on Biomaterials ESB2017, Athens, 2017.
  38. Leiro, V; Santos, S.D.; Lopes, C.D.F.; Xavier M.A; Leite, D; Tomás, H; Pêgo, A.P.. "PEGylated PAMAM dendrimers can effectively reach the injured ischemic brain". Paper presented in 6th China-Europe Symposium on Biomaterials in Regenerative Medicine CESB2017, Porto, 2017.
  39. Leiro, V. "On the biodegradability of PEG-Dendritic Block Copolymers for siRNA Delivery". Paper presented in 6th China-Europe Symposium on Biomaterials in Regenerative Medicine CESB2017, Porto, 2017.
  40. Leiro, V; Santos SD; Lopes CDF; Xavier MA; Leite, D.; Tomás, H.; Pêgo, A.P.. "PEGylated PAMAM dendrimers can effectively reach the injured ischemic brain". Paper presented in 6th China-Europe Symposium on Biomaterials in Regenerative Medicine CESB2017, Porto, 2017.
  41. Santos SD; Leiro, V; Lopes CDF; Xavier MA; Leite, D.; Tomás, H.; Pêgo AP. "Blood-Brain Barrier Transport and Brain Uptake of Poly(Ethylene Glycol)-Modified PAMAM Dendrimers in brain ischemia". Paper presented in XV Meeting of the Portuguese Society for Neuroscience, Braga, 2017.
  42. Leiro, V. "Biodegradable PEG-GATGE dendritic block copolymers: synthesis and potential as siRNA vectors". Paper presented in MAD–Nano16: Emerging Trends and Future of Nanomaterials for Human Health, 2016.
  43. Leiro, V; Garcia, J.P; Moreno, P; Fernandez-Megia, E.; Pêgo, A.P.. "Biodegradable PEG-Dendritic Block Copolymers: Synthesis and Potential as Nucleic Acid Vectors". Paper presented in 5th I3S Retreat Annual Meeting. Póvoa do Varzim, Portugal, Póvoa de Varzim, 2016.
  44. Leiro, V. "Biodegradable Dendritic Structures: Synthesis and Biofunctionality Assessment as Nucleic Acid Vectors". Paper presented in 11th International Symposium on Polymer Therapeutics: From Laboratory to Clinical Practice, Valencia, Spain, Valencia, 2016.
  45. Gomes C.; Varela-Moreira A; Gomez-Lazaro M; Lópes C.; Leiro, V; Moreno P.; Pêgo A.P. "Tailored trimethyl chitosan nanoparticles for specific gene delivery to the nervous system". Paper presented in European Society of Gene and Cell Therapy and Finnish Society of Gene Therapy Collaborative Congress, Helsinki, 2015.
  46. Garcia, J.P; Leiro, V; Moreno P.; Fernandez-Megia, E.; Pêgo A.P.. "PEG-GATG dendritic block copolymers for siRNA delivery". Paper presented in III AEICBAS Biomedical Congress. Porto, Portugal, Porto, 2015.
  47. Leiro, V; Garcia J; Moreno, P; Fernandez-Megia, E; Pêgo, A.P.. "Functionalization of PEG-GATG dendrimers: a new strategy for siRNA delivery". Paper presented in 6th Symposium on Bioengineering, Porto, 2014.
  48. Leiro, V; Garcia J; Moreno P; Fernandez-Megia E; Pêgo A.P. "Exploring PEG-GATG dendritic block copolymers as siRNA carriers". Paper presented in 4th I3S Retreat Annual Meeting, Póvoa de Varzim, 2014.
  49. Leiro, V; Fernandez-Megia, E; Pêgo, A.P.. "Desing of Biodegradable GATG Dendrimers for DNA/RNA Delivery". Paper presented in IV Encuentro sobre Dendrímeros EDEN, Santiago de Compostela, 2014.
  50. Leiro, V; Riguera, R.; Fernandez-Megia, E.; Pêgo, A.P. "Designing New Biodegradable Dendrimers for Delivery of Nucleic Acids". Paper presented in 25th European Conference on Biomaterials ESB2013, Madrid, 2013.
  51. Leiro, V; Seco, J.M; Quiñoá, E.; Riguera, R.. "A Single Derivatization Method to Assign the Configuration of Amino Alcohols by Low Temperature NMR". Paper presented in V Simposio de Investigadores Jóvenes Real Sociedad Española de Química – Sigma Aldrich, Santiago de Compostela, 2008.
  52. Leiro, V; Seco, J.M.; Quiñoa, E; Riguera, R.. "The Absolute Configuration of Amino Alcohols by NMR: Mutual Interaction Between Auxiliaries". Paper presented in IV Reunión Bienal del Grupo Especializado de RMN de la RSEQ – I Reunión Ibérica de RMN, Sevilla, 2008.
  53. Leiro, V; Seco, J.M.; Quiñoa, E.; Riguera, R.. "The assignment of absolute configuration of polyfunctional compounds by NMR: Amino alcohols". Paper presented in III Reunión Bienal del Grupo Especializado de RMN de la RSEQ, Alicante, 2006.
  54. Leiro, V; Seco, J.M.; Quiñoa, E; Riguera, R.. "NMR method for the assignment of absolute configuration of chiral amino alcohols (secondary/secondary)". Paper presented in 4th Spanish-Portuguese-Japanese Organic Chemistry Symposium, Santiago de Compostela, 2006.
  55. Leiro, V; Pazos, Y; Seco, J.M; Quiñoa, E; Riguera, R. "Boc-phenylglycine: A noncovalent method for the determination of the absolute configuration of aminoalcohols and their ethers by NMR". Paper presented in 5th Spanish-Italian Symposium on Organic Chemistry, Santiago de Compostela, 2004.
  56. Leiro, V; Pazos, Y; Seco, J.M; Quiñoa, E.; Riguera, R. "Boc-phenylglycine as CSA for the determination of the absolute configuration of amino alcohols and their ethers by NMR". Paper presented in II Reunión Bienal del Grupo Especializado de RMN de la RSEQ, Santiago de Compostela, 2004.
Conference paper
  1. Torrado, Marília; Leiro, Victoria (7713-0BE4-AC65); Santos, Sofia Duque; Pêgo, Ana. "New Nanobiomaterials for Stroke Neuroprotection and Neurorecovery: A Novel Biodegradable Vector Applied In Vivo for mRNA Therapeutics". Paper presented in XLIV Congreso de la Sociedad Ibérica de Biomecánica y Biomateriales, Cáceres, 2022.
    Published
Conference poster
  1. Moreira, Débora; Santos, SD; Leiro, Victoria; Pêgo, Ana. "Dendrimers as Alzheimer´s Disease Nanotherapeutics: Exploring their Effect on Aß1-42 Fibrillation.". 2023.
  2. Sara Zarzo-Arias; Leiro, Victoria; Pêgo, Ana. "The potential of fully biodegradable dendritic vectors to deliver nucleic acids to cartilage tissue". Paper presented in 33rd Annual Conference of the European Society for Biomaterials, 2023.
  3. Marília Torrado; Leiro, Victoria; Santos, Sofia Duque; Pêgo, Ana Paula. Corresponding author: Marília Torrado. "Engineering Botulinum Neurotoxins towards an innovative neuroprotective nanosystem in the context of stroke". Paper presented in ETOX 2023 - European Workshop on Bacterial Protein Toxins, 2023.
  4. António Miguel Ramôa; Filipa Campos; Luís Moreira; Teixeira, Catia; Leiro, Victoria; Gomes, Paula; das Neves, José; M. Cristina L. Martins; Monteiro, Claudia. "Nanopartículas de PLGA-PEG com péptidos antimicrobianos covalentemente ligados para combater infeções bacterianas em feridas". Paper presented in Sociedade Portuguesa de Diabetologia (SPD), 2023.
  5. Marília Torrado; Clara Synthon; Leiro, Victoria; Santos, Sofia Duque; Pêgo, Ana. "Biodegradable dendrimers as shuttles to neuroprotection: Final stop - the ischemic brain". Paper presented in 5th PhDay: "Building Paths: The Science Behind Us". Porto, Portugal, 2022.
  6. Spencer, Ana; Xavier, Miguel; Guimarães, Sofia Cunha; Leiro, Victoria; Pêgo, Ana Paula. "Exploring Microfluidics as a Neuro-platform Towards the Design of a Novel Targeted Dendritic Vectors". Paper presented in 32nd Annual Conference of the European Society for Biomaterials (ESB), 2022.
  7. Spencer, Ana; Xavier, Miguel; Guimarães, Sofia Cunha; Victoria Leiro; Pêgo, Ana. "Exploring Microfluidics as a Neuro-platform Towards the Design of a Novel Targeted Dendritic Vector". Paper presented in 32nd Annual Conference of the European Society for Biomaterials (ESB), 2022.
  8. Pedro M. Alves; Rúben F. Pereira; Costa, Beatriz; Natália Tassi; Teixeira, Catia; Leiro, Victoria; Gomes, Paula; Pêgo, Ana. "Hang in there: efficient antimicrobial peptide conjugation produces cationic peptidopolysaccharide surfaces with antimicrobial activity". Paper presented in 32nd Annual Conference of the European Society for Biomaterials (ESB 2022), 2022.
  9. Spencer, Ana; Xavier, Miguel; Guimarães, Ana Sofia; Leiro, Victoria; Pêgo, Ana Paula. "Microfluidics for the assessment of nanoparticle intracellular trafficking in neurons". Paper presented in FENS Forum 2022 | International Neuroscience Conference. Paris, France, 2022.
  10. Torrado, Marília; Clara Synthon; Leiro, Victoria; Santos, Sofia Duque; Pêgo, Ana. "Exploring biodegradable dendrimers as carriers of CNS neuroprotective therapeutics". Paper presented in 2nd International Meeting of the Portuguese Research Network on SpinalCord Injury. Porto, Portugal, 2022.
  11. Márcia Saraiva; Pêgo, Ana; Leiro, Victoria. "Fully biodegradable polyamine-terminated PEG-GATGE dendrimers as siRNA vectors to cancer cells". Paper presented in IJUP – Investigação Jovem da U.Porto 15ª Edition, 2022.
  12. Moreira, Débora; Santos, Sofia Duque; Victoria Leiro; Pêgo, Ana. "Exploring the antiamyloidogenic properties of dendrimers for an Alzheimer's disease nanotherapy". Paper presented in Innovation in Doctoral Education, 2022.
  13. Pedro M. Alves; Rúben F. Pereira; Costa, Beatriz; Natália Tassi; Teixeira, Catia; Leiro, Victoria; Gomes, Paula; Costa, Fabíola; M. Cristina L. Martins. "Fighting biofilm-forming bacteria with highly efficient light-induced chemoselective conjugation of antimicrobial peptides onto chitosan". Paper presented in 8th Thesinge Biofilm Conference. Thesinge, The Netherlands, 2022.
  14. Diana R. Fonseca; Francesca Annis; Moura, Ana; Seabra, Catarina Leal; Victoria Leiro; Berta N. Estevinho; Teixeira, Catia; et al. "Beyond antibiotics: Pexiganan A-grafted microspheres to clear H. pylori infection". Paper presented in 3rd BioIberoamerica 2022, 2022.
  15. Silva, Duarte; Pêgo, Ana; Leiro, Victoria. "Novel biodegradable PEG-dendrimers: Gene therapy vectors for a new age". Paper presented in AIMS- Annual International (bio) Medical Students Meeting Research Competition. Lisboa, Portugal, 2022.
  16. Spencer AP; Leiro, Victoria; Pêgo AP. "Designing a new targeted fully biodegradable dendrimer for delivery of nucleic acids to neuronal cells". Paper presented in XVII Congresso da Sociedade Portuguesa de Neurociências, 2021.
  17. Spencer, AP; Leiro, Victoria; Pêgo AP. "Looking for a neuro-solution: Designing a new targeted vector for nucleic acid delivery to neuronal cells". Paper presented in 4th PhDay: Break borders and build opportunities, 2021.
  18. Leiro, Victoria; Spencer AP; Magalhães N; Pêgo AP. "Multivalent fully biodegradable PEGdendrimers as versatile nanotherapeutics: application in gene therapy". Paper presented in 31st Conference of the European Society for Biomaterials ESB2021, 2021.
  19. Moreira, D; Santos, SD; Leiro, Victoria; Pêgo AP. "Exploring the antiamyloidogenic properties of dendrimers for an Alzheimer’s disease nanotherapy". Paper presented in 31st Conference of the European Society for Biomaterials ESB2021, 2021.
  20. Râmoa A; Moreira L; Teixeira C; Leiro, Victoria; Gomes P; das Neves J; Martins MCL; Monteiro C. "AMP-grafted PLGA-PEG Nanoparticles to Fight Bacterial Wound Infections". Paper presented in 31st Conference of the European Society for Biomaterials ESB2021, 2021.
  21. Fonseca DR; Moura A; Seabra CL; Gomes S; Oliveira JM; Reis RL; Leiro, Victoria; et al. "Gellan Gum hydrogels as a pH-responsive system to control the gastric delivery of highly effective antimicrobial microspheres against Helicobacter pylori". Paper presented in XXXIVth Workshop of the European Helicobacter and Microbiota Study Group - EHMSG 2021, 2021.
  22. Leiro, Victoria; Spencer, AP; Magalhães, N; Pêgo, AP. "Fully biodegradable PEG-dendrimers as versatile vectors for nucleic acid delivery". Paper presented in 1st Symposium on Oligonucleotide Technologies and Therapeutics@Portugal – OTP2021, 2021.
  23. Spencer, AP; Leiro, V; Pêgo, AP. "Dendrivolution: designing a new targeted dendrimer for nucleic acid delivery to neuronal cells". Paper presented in 1st Symposium on Oligonucleotide Technologies and Therapeutics@Portugal ¿ OTP2021, 2021.
  24. Silva, Duarte; Paula Pêgo, Ana; Leiro, Victoria (7713-0BE4-AC65). "Surface Engineering of Fully Biodegradable Dendrimers to act as promising siRNA vectors". Paper presented in 4th Doctoral Congress in Engineering (DCE 2021), 2021.
  25. Moreira, Débora; Leiro, Victoria; Duque Santos, Sofia; Paula Pêgo, A.. "Dendrimers as nanotherapeutics for Alzheimer’s disease". Paper presented in 4th Doctoral Congress in Engineering (DCE 2021), 2021.
  26. Fonseca DR; Moura A; Seabra CL; Gomes S; Oliveira JM; Reis RL; Leiro, Victoria; et al. "When Helicobacter pylori met pexiganan Agrafted chitosan microspheres: a fateful story". Paper presented in 4th Doctoral Congress in Engineering (DCE 2021), 2021.
  27. Pedro Alves; Ruben Pereira; Beatriz Costa; Natália Tassi; Cátia Teixeira; Leiro, Victoria; Paula Gomes; Fabiola Costa; M. Cristina L. Martins. "When dialysis gets ¿mesh¿y: removal of adsorbed peptide from high molecular weight chitosan to yield a contact-killing biomaterial". Paper presented in Doctoral Congress in Engineering 2021, 2021.
  28. Fonseca, Diana R.; Ana Moura; Seabra, Catarina Leal; Leiro, Victoria; Cátia Teixeira; Paula Gomes; Parreira, Paula; M. Cristina L. Martins. "Pexiganan A-grafted chitosan microspheres as the gastric infection management future". Paper presented in EuroNanoForum 2021, 2021.
  29. Torrado M; Santos, SD; Leiro, Victoria; Pêgo, Ana. "Tackling the beginnings of DETOX: an innovative neuroprotective nanosystem at the". Paper presented in 3rd PhDay Back to the Future. i3S Institute for Research and Innovation in Health, Porto (Portugal)., 2020.
  30. Fonseca, Diana R.; Moura, Ana; Seabra, Catarina Leal; Leiro, Victoria; B. N. Estevinho; Gomes, Paula; Teixeira, Catia; Parreira, Paula; Martins, MCL. "A deadly hug: chitosan microspheres functionalized with MSI-78A antimicrobial peptide kill Helicobacter pylori. 33rd Workshop of the European Helicobacter and Microbiota Study Group". Paper presented in 33rd Workshop of the European Helicobacter and Microbiota Study Group, 2020.
  31. Torrado, Marília; Leiro, V; Santos SD; Pêgo AP. "From bench to ischemic brain: Biodegradable dendrimers as novel tools to be applied as a neuroprotective strategy". Paper presented in 12th FENS Forum of Neuroscience, Glasgow, UK, 2020.
  32. Torrado, Marília; Leiro, Victoria; Santos, Sofia Duque; Pêgo, Ana Paula. Corresponding author: Torrado, Marília. "From bench to the ischemic brain: Biodegradable dendrimers as novel tools to be applied as a neuroprotective strategy". Paper presented in FENS 2020 Virtual Forum, 2020.
  33. Leiro, V; Fonseca DR; Moura Ana; Seabra CL; Estevinho B; Gomes Paula; Parreira, Paula; Martins MCL. "A deadly hug: chitosan microspheres functionalized with MSI-78A antimicrobial peptide kill Helicobacter pylori". Paper presented in European Helicobacter and Microbiota Study Group – EHMSG. Glasgow, UK, 2020.
  34. Leiro, V; Spencer, Ana Patrícia; Pêgo, Ana. "Designing a new targeted fully biodegradable dendrimer for delivery of nucleic acids to neuronal cells". Paper presented in 11th World Biomaterials Congress 2020. Glasgow, UK, 2020.
  35. Leiro, V; Marília Torrado; Santos, SD; Pêgo, Ana Paula. "Tackling the beginnings of DETOX: an innovative neuroprotective nanosystem". Paper presented in 3rd PhDay: Back to the Future. Porto, Portugal., 2020.
  36. Leiro, V; Ana Patrícia Spencer; Pêgo, Ana Paula. "Designing a new fully biodegradable nanovector for neurotargeted delivery". Paper presented in 22nd EMBL PhD Symposium: The Roaring 20s: A New Decade for Life Sciences. Heidelberg, Germany, 2020.
  37. Leiro, V; Spencer AP; Pêgo, AP. "Novel fully biodegradable PEG-dendrimers: Synthesis and function as efficient vehicles of siRNA to neuronal cells". Paper presented in 8th i3S Annual Meeting. Póvoa de Varzim, Portugal, 2019.
  38. Custódio, Beatriz; Magalhães N.; Marques JF; Silva-Reis SC; Mota P; Leiro, V; Bessa J; Santos SD; Pêgo, A.P. "The blood-brain barrier as a challenge to face in the delivery of nucleic acids mediated by dendrimers in brain ischemia". Paper presented in 8th i3S Annual Meeting. Póvoa de Varzim, Portugal, 2019.
  39. Fonseca DR; Moura A.; Seabra CL; Leiro, V; Estevinho B; Gomes P.; Parreira, P.; Martins MCL. "Chitosan microspheres immobilized MSI-78A Antimicrobial Peptidefor Helicobacter pylori Infection Management". Paper presented in 8th i3S Annual Meeting. Póvoa de Varzim, Portugal, 2019.
  40. Santos SD; Bola DC; Teixeira S.; Sousa SS; Leiro, V; Pêgo, A.P. "Unravelling the potential of chitosanderived nanoparticles for therapeutic synergism in stroke using antagomiR technology and neurotrophin mimetics". Paper presented in 8th i3S Annual Meeting. Póvoa de Varzim, Portugal, 2019.
  41. Spencer AP; Leiro, V; Pêgo, A.P.. "The biological assessment of an innovative family of fully biodegradable dendrimers as siRNA delivery vectors". Paper presented in 8th i3S Annual Meeting. Póvoa de Varzim, Portugal, 2019.
  42. Mota P; Silva-Reis SC; Pêgo, A.P.; Leiro, V. "Scale-up synthesis of PEG-dendrimers to act as nucleic acids vectors". Paper presented in 8th i3S Annual Meeting. Póvoa de Varzim, Portugal, 2019.
  43. Silva-Reis SC; Mota P; Pêgo, A.P; Leiro, V. "Innovative Biodegradable Dendrimers to act as Novel Nanocarriers for Nucleic Acids Delivery – Design and Synthesis Approaches". Paper presented in 8th i3S Annual Meeting. Póvoa de Varzim, Portugal, 2019.
  44. Spencer AP; Magalhães N.; Leiro, V; Pêgo, AP. "Innovative fully biodegradable PEG-dendritic block copolymers: biological assessment as siRNA delivery vectors". Paper presented in IDS11 - 11th International Dendrimer Symposium. Funchal, Madeira, Portugal, 2019.
  45. Custódio, Beatriz; Magalhães, Natália; Leiro, Victoria; Santos, Sofia Duque; Pêgo, Ana Paula. "In vitro assessment of the blood brain barrier permeation with dendrimers transporting nucleic acids in ischemia". Paper presented in 7th Advanced Summer School, 2019.
  46. Torrado, Marília; Leiro, Victoria; Santos, Sofia Duque; Pêgo, Ana Paula. Corresponding author: Torrado, Marília. "Biodegradable dendrimers as delivery systems: Developing a neuroprotective strategy to reach ischemic neurons". Paper presented in Interrogations at the Biointerface - 7th Advanced Summer School, Porto, Portugal, 2019.
  47. Santos SD; Xavier, M.; Leite DM; Moreira DA.; Custódio, Beatriz; Torrado, M.; Castro, R.; et al. "The transport of therapeutic molecules to the ischemic brain: dendrimers as carriers in pre-clinical studies". Paper presented in XVI Meeting of the Portuguese Society for Neuroscience. Lisbon, Portugal, 2019.
  48. Torrado, M.; Leiro, V; Santos SD; Pêgo, AP. "Biodegradable dendrimers as novel tools to deliver neuroprotective nucleic acids in stroke". Paper presented in XVI Meeting of the Portuguese Society for Neuroscience. Lisbon, Portugal, 2019.
  49. Leiro, V; Spencer, A.P.; Magalhães N.; Torrado, M.; Santos SD; Pêgo, AP; Ana Patrícia Spencer; et al. "On the Fully Biodegradablity of PEG-Dendrimers for Nucleic Acids (siRNA & mRNA) Delivery". Paper presented in Tanja Weil Group Retreat. Ebernburg, Germany, 2019.
  50. Spencer AP; Leiro, V; Pêgo, A.P. "New Fully Biodegradable Dendrimers as nanocarriers for siRNA". Paper presented in 6th IEEE Portuguese Meeting on Bioengineering (ENBENG 2019). Lisboa, Portugal, 2019.
  51. Fonseca, Diana R.; Moura, Ana; Seabra, Catarina Leal; Leiro, Victoria; Estevinho, Berta; Gomes, Paula; Parreira, Paula; Martins, M. Cristina L.. "MSI-78A antimicrobial peptide immobilized onto chitosan microspheres for helicobacter pylori infection management". Paper presented in 8th I3S meeting, 2019.
  52. Torrado, Marília; Leiro, Victoria; Santos, Sofia Duque; Pêgo, Ana Paula. Corresponding author: Torrado, Marília. "Biological assessment of PEG based dendrimers for neuroprotective therapies in stroke". Paper presented in 7th i3S annual meeting, 2018.
  53. Spencer AP; Magalhães N.; Leiro, V; Pêgo, AP. "New Fully Biodegradable PEG-Dendrimers: Promising non-viral delivery vectors for siRNA delivery". Paper presented in 7th i3S Annual Meeting. Póvoa do Varzim, Portugal, 2018.
  54. Magalhães N.; Pêgo AP; Leiro, V. "Synthesis and functionalization of PEG-dendrimers". Paper presented in 7th i3S Annual Meeting. Póvoa do Varzim, Portugal, 2018.
  55. Torrado, M.; Santos SD; Leiro, V; Pêgo, AP. "Biological assessment of biodegradable dendrimers for targeted neuroprotective therapies in stroke". Paper presented in 7th i3S Annual Meeting. Póvoa do Varzim, Portugal, 2018.
  56. Neto TM; Ferreira-da-Silva F; Leiro, V; Moreno, P; Amaral IF. "Development of an injectable self-assembled bioactive hybrid hydrogel". Paper presented in 7th i3S Annual Meeting. Póvoa do Varzim, Portugal, 2018.
  57. Moura A.; Seabra C.; Leiro, V; Estevinho B; Gomes P.; Parreira, P.; Martins CL. "Antibiotic Free Nano/Microparticles to Fight Helicobacter pylori". Paper presented in 7th i3S Annual Meeting. Póvoa do Varzim, Portugal, 2018.
  58. Santos SD; Xavier MA; Leite DM; Moreira DA; Castro, R.; Leiro, V; Rodrigues, J.; Tomás, H.; Pêgo, AP. "Nanoparticle-mediated Blood-Brain Barrier Transport for Neuronal Delivery in Focal Brain Ischemia". Paper presented in 10th International Symposium on Neuroprotection and Neurorepair. Dresden (Radebeul), Germany, 2018.
  59. Gomes CP; Leiro, V; Lopes CDF; Pêgo, AP. "Fine tuning neuronal targeting of nanoparticles for nucleic acid delivery". Paper presented in 29th Annual Meeting of the European Society for Biomaterials, Maastricht, the Netherlands, 2018.
  60. Leiro, V; Spencer AP; Magalhães N; Pêgo, AP. "On the Fully Biodegradability of PEG-Dendrimers for siRNA Delivery". Paper presented in 12th International Symposium on Polymer Therapeutics: From Laboratory to Clinical Practice, Valencia, Spain, 2018.
  61. Leiro, V; Spencer AP; Magalhães N.; Pêgo, AP. "Synthesis and Functionalization of Novel Fully Biodegradable PEG-Dendrimers to Act as Nucleic Acid Vectors". Paper presented in i3S Annual Meeting 2017. Póvoa de Varzim, Portugal, 2017.
  62. Santos SD; Leiro, V; Lopes CDF; Xavier MA; Leite, D.; Tomás H; Pêgo, AP. "PAMAM dendrimers as delivery vehicle in the injured ischemic brain". Paper presented in i3S Annual Meeting 2017. Póvoa de Varzim, Portugal, 2017.
  63. Santos, S.D.; Leiro, V; Lopes, C.D.F.; Xavier M.A; Leite, D.; Tomás, H.; Pêgo, A.P.. "PEGylated PAMAM dendrimers can effectively reach the injured ischemic brain". Paper presented in 6th China-Europe Symposium on Biomaterials in Regenerative Medicine CESB2017. Porto, Portugal., 2017.
  64. Santos SD; Leiro, V; Lopes CDF; Xavier MA; Leite, D.; Tomás, H.; Pêgo, AP. "Blood-Brain Barrier Transport and Brain Uptake of Poly(Ethylene Glycol)-Modified PAMAM Dendrimers in brain ischemia". Paper presented in XV Meeting of the Portuguese Society for Neuroscience., Braga, Portugal, 2017.
  65. Leiro, V; Garcia, J.P.; Moreno, P; Fernandez-Megia, E.; Pêgo, A.P.. "Biodegradable PEG-Dendritic Block Copolymers: Synthesis and Potential as Nucleic Acid Vectors". Paper presented in 5th I3S Retreat Annual Meeting. Póvoa do Varzim, Portugal, 2016.
  66. Leiro, V; Garcia, J.P; Moreno, P; Fernandez-Megia, E; Pêgo, A.P.. "Biodegradable Dendritic Structures: Synthesis and Biofunctionality Assessment as Nucleic Acid Vectors". Paper presented in 11th International Symposium on Polymer Therapeutics: From Laboratory to Clinical Practice, Valencia, Spain, 2016.
  67. Garcia, J.P.; Leiro, V; Moreno P; Fernandez-Megia, E; Pêgo, A.P.. "PEG-GATG dendritic block copolymers for siRNA delivery". Paper presented in III AEICBAS Biomedical Congress. Porto, Portugal, 2015.
  68. Leiro, V; Garcia J; Moreno P; Fernandez-Megia, E; Pêgo, A.P.. "Functionalization of PEG-GATG dendrimers: a new strategy for siRNA delivery". Paper presented in 6th Symposium on Bioengineering. Porto, Portugal, 2014.
  69. Leiro, V; Garcia J; Moreno P; Fernandez-Megia, E; Pêgo, A.P.. "Exploring PEG-GATG dendritic block copolymers as siRNA carriers". Paper presented in 4th I3S Retreat Annual Meeting. Póvoa do Varzim, Portugal, 2014.
  70. Leiro, V; Fernandez-Megia, E; Pêgo, A.P. "Desing of Biodegradable GATG Dendrimers for DNA/RNA Delivery". Paper presented in IV Encuentro sobre Dendrímeros EDEN 4. Santiago de Compostela, Spain., 2014.
  71. Leiro, V; Riguera, R.; Fernandez-Megia, E.; Pêgo, A.P.. "Designing New Biodegradable Dendrimers for Delivery of Nucleic Acids". Paper presented in 25th European Conference on Biomaterials ESB2013. Madrid, Spain., 2013.
  72. Leiro, V; Seco, J.M.; Quiñoá, E.; Riguera, R.. "A Single Derivatization Method to Assign the Configuration of Amino Alcohols by Low Temperature NMR". Paper presented in V Simposio de Investigadores Jóvenes Real Sociedad Española de Química – Sigma Aldrich. Santiago de Compostela, Spain., 2008.
  73. Leiro, V; Seco, J.M.; Quiñoá, E.; Riguera, R.. "The Absolute Configuration of Amino Alcohols by NMR: Mutual Interaction Between Auxiliaries". Paper presented in IV Reunión Bienal del Grupo Especializado de RMN de la RSEQ – I Reunión Ibérica de RMN. Sevilla, Spain, 2008.
  74. Leiro, V; Seco, J.M; Quiñoa, E.; Riguera, R. "The assignment of absolute configuration of polyfunctional compounds by NMR: Amino alcohols". Paper presented in III Reunión Bienal del Grupo Especializado de RMN de la RSEQ. Sant Joan – Alicante, Spain, 2006.
  75. Leiro, V; Seco, J.M.; Quiñoa, E.; Riguera, R. "NMR method for the assignment of absolute configuration of chiral amino alcohols (secondary/secondary)". Paper presented in 4th Spanish-Portuguese-Japanese Organic Chemistry Symposium. Santiago de Compostela, Spain, 2006.
  76. Leiro, V; Pazos, Y; Seco, J.M.; Quiñoa, E.; Riguera, R. "Boc-phenylglycine: A noncovalent method for the determination of the absolute configuration of aminoalcohols and their ethers by NMR". Paper presented in 5th Spanish-Italian Symposium on Organic Chemistry. Santiago de Compostela, Spain, 2004.
  77. Leiro, V; Pazos, Y; Seco, J.M; Quiñoa, E; Riguera, R. "Boc-phenylglycine as CSA for the determination of the absolute configuration of amino alcohols and their ethers by NMR". Paper presented in II Reunión Bienal del Grupo Especializado de RMN de la RSEQ. Santiago de Compostela, Spain, 2004.
Journal article
  1. Custódio, Beatriz; Carneiro, Patricia; Joana Marquês; Leiro, Victoria; Ana M. Valentim; Mafalda Sousa; Santos, Sofia Duque; José Bessa; Pêgo, Ana. "Biological response following the systemic injection in zebrafish of PEG-PAMAM-Rhodamine conjugates". Pharmaceutics 16 5 (2024): 608. https://www.mdpi.com/1999-4923/16/5/608.
    Published • https://www.mdpi.com/1999-4923/16/5/608
  2. Spencer, Ana; Xavier, Miguel; Guimarães, Ana Sofia; adriana vilaça; Ariel Ionescu; Rafael Santos; Gomez-Lazaro, Maria; et al. "Unveiling the potential of neuron-targeted dendriplexes for siRNA with a PNS-CNS-on-chip model". Nano Today (2024):
    Submitted
  3. Spencer, Ana; Adriana Vilaça; Guimarães, Ana Sofia; Xavier, Miguel; Rafael Santos; Ariel Ionescu; Gomez-Lazaro, Maria; et al. "Advancing neurotherapeutics: chitosan nanoparticles as efficient vehicles for siRNA delivery". Small (2024):
    Submitted
  4. Spencer, Ana; Leiro, Victoria; Pêgo, Ana Paula. "Unravelling the interactions of biodegradable dendritic nucleic acid carriers and neural cells". Biomaterials Science 11 (2023): 1499-1516.
    Published • https://doi.org/10.1039/D2BM01114J
  5. Maura Cimino; Parreira, Paula; Leiro, Victoria; Sousa, Aureliana; Gonçalves, Raquel; Barrias, Cristina; M. Cristina L. Martins. "Enhancement of hMSC in vitro Proliferation by Surface Immobilization of a Heparin-Binding Peptide". Molecules 28 (2023): 3422.
    Published • doi.org/10.3390/ molecules28083422
  6. Moreira, Débora; Santos, Sofia Duque; Leiro, Victoria; Pêgo, Ana. "Dendrimers and Derivatives as Multifunctional Nanotherapeutics for Alzheimer's Disease". Pharmaceutics 15 4 (2023): 1054.
    Published • https://doi.org/10.3390/pharmaceutics15041054
  7. António Miguel Ramôa; Campos, Filipa; MOREIRA, LUÍS; Teixeira, Catia; Leiro, Victoria; Gomes, Paula; das Neves, José; M. Cristina L. Martins; Monteiro, Cláudia. "Antimicrobial peptide-grafted PLGA-PEG Nanoparticles to Fight Bacterial Wound Infections". Biomaterials Science 11 (2022): 499-508.
    Published
  8. Pedro M. Alves; Rúben F. Pereira; Costa, Beatriz; Natália Tassi; Teixeira, Catia; Leiro, Victoria; Monteiro, Cláudia; et al. "Thiol-Norbornene Photoclick Chemistry for Grafting Antimicrobial Peptides onto Chitosan to Create Antibacterial Biomaterials". ACS Applied Polymer Materials 4 7 (2022): 5012-5026.
    Published
  9. Leiro, Victoria (7713-0BE4-AC65); Spencer, Ana; Natália Magalhães; Pêgo, Ana Paula. "Biodegradable dendrimers as versatile nanotherapeutics". Biomaterials 281 (2022): 121356.
    Published • 10.1016/j.biomaterials.2021.121356
  10. Diana R. Fonseca; Moura, Ana; Leiro, Victoria (7713-0BE4-AC65); Silva-Carvalho, Ricardo; Berta Nogueiro Estevinho; Seabra, Catarina Leal; Patrícia C. Henriques; et al. "Grafting MSI-78A onto chitosan microspheres enhances its antimicrobial activity". Acta Biomaterialia 137 (2022): 186-198.
    Published • 10.1016/j.actbio.2021.09.063
  11. Spencer AP; Torrado, Marília; Custódio, Beatriz; Silva-Reis SC; Santos SD; Leiro, Victoria (7713-0BE4-AC65); Pêgo AP. "Breaking barriers: Bioinspired strategies for targeted delivery to the central nervous system". Pharmaceutics 12 (2020): 192. https://www.mdpi.com/1999-4923/12/2/192/htm.
    Published • 10.3390/pharmaceutics12020192
  12. Spencer, Ana P.; Torrado, Marília; Custódio, Beatriz; Sara C. Silva-Reis; Santos, Sofia D.; Leiro, Victoria; Pêgo, Ana P.. "Breaking Barriers: Bioinspired Strategies for Targeted Neuronal Delivery to the Central Nervous System". Pharmaceutics 12 2 (2020): 192. http://dx.doi.org/10.3390/pharmaceutics12020192.
    Published • 10.3390/pharmaceutics12020192
  13. Santos, Sofia D.; Xavier, Miguel; Leite, Diana M.; Moreira, Débora A.; Custódio, Beatriz; Torrado, Marília; Castro, Rita; et al. "PAMAM dendrimers: blood-brain barrier transport and neuronal uptake after focal brain ischemia". Journal of Controlled Release 291 (2018): 65-79. http://dx.doi.org/10.1016/j.jconrel.2018.10.006.
    10.1016/j.jconrel.2018.10.006
  14. Pereira Gomes, Carla; Leiro, Victoria; Ferreira Lopes, Cátia Daniela; Spencer, Ana Patrícia; Pêgo, Ana Paula. "Fine tuning neuronal targeting of nanoparticles by adjusting the ligand grafting density and combining PEG spacers of different length". Acta Biomaterialia 78 (2018): 247-259. http://dx.doi.org/10.1016/j.actbio.2018.08.005.
    10.1016/j.actbio.2018.08.005
  15. Leiro, Victoria; Santos, Sofia Duque; Pego, Ana Paula. "Delivering siRNA with Dendrimers: In Vivo Applications". Current Gene Therapy 17 2 (2017): http://dx.doi.org/10.2174/1566523217666170510160527.
    10.2174/1566523217666170510160527
  16. Leiro, Victoria; Duque Santos, Sofia; Lopes, Cátia D. F.; Paula Pêgo, Ana. "Dendrimers as Powerful Building Blocks in Central Nervous System Disease: Headed for Successful Nanomedicine". Advanced Functional Materials 28 12 (2017): 1700313. http://dx.doi.org/10.1002/adfm.201700313.
    10.1002/adfm.201700313
  17. Leiro, Victoria; Garcia, João Pedro; Moreno, Pedro M. D.; Spencer, Ana Patrícia; Fernandez-Villamarin, Marcos; Riguera, Ricardo; Fernandez-Megia, Eduardo; Paula Pêgo, Ana. "Biodegradable PEG–dendritic block copolymers: synthesis and biofunctionality assessment as vectors of siRNA". Journal of Materials Chemistry B 5 25 (2017): 4901-4917. http://dx.doi.org/10.1039/c7tb00279c.
    10.1039/c7tb00279c
  18. Gomes, Carla P.; Varela-Moreira, Aida; Leiro, Victoria; Lopes, Cátia D.F.; Moreno, Pedro M.D.; Gomez-Lazaro, Maria; Pêgo, Ana P.. "A high-throughput bioimaging study to assess the impact of chitosan-based nanoparticle degradation on DNA delivery performance". Acta Biomaterialia 46 (2016): 129-140. http://dx.doi.org/10.1016/j.actbio.2016.09.037.
    10.1016/j.actbio.2016.09.037
  19. Moreno, Pedro M. D.; Santos, Joyce C.; Gomes, Carla P.; Varela-Moreira, Aida; Costa, Artur; Leiro, Victoria; Mansur, Herman; Pêgo, Ana P.. "Delivery of Splice Switching Oligonucleotides by Amphiphilic Chitosan-Based Nanoparticles". Molecular Pharmaceutics 13 2 (2016): 344-356. http://dx.doi.org/10.1021/acs.molpharmaceut.5b00538.
    10.1021/acs.molpharmaceut.5b00538
  20. Leiro, Victoria; Garcia, João Pedro; Tomás, Helena; Pêgo, Ana Paula. "The Present and the Future of Degradable Dendrimers and Derivatives in Theranostics". Bioconjugate Chemistry 26 7 (2015): 1182-1197. http://dx.doi.org/10.1021/bc5006224.
    10.1021/bc5006224
  21. Santos, Joyce C. C.; Moreno, Pedro M. D.; Mansur, Alexandra A. P.; Leiro, Victoria; Mansur, Herman S.; Pêgo, Ana Paula. "Functionalized chitosan derivatives as nonviral vectors: physicochemical properties of acylated N,N,N-trimethyl chitosan/oligonucleotide nanopolyplexes". Soft Matter 11 41 (2015): 8113-8125. http://dx.doi.org/10.1039/c5sm01403d.
    10.1039/c5sm01403d
  22. Leiro, Victoria; Seco, José Manuel; Quiñoá, Emilio; Riguera, Ricardo. "Using a Combination of Magnetic Anisotropic Effects for the Configurational Assignment of Amino Alcohols". Chemistry - An Asian Journal 5 9 (2010): 2106-2112. http://dx.doi.org/10.1002/asia.201000229.
    10.1002/asia.201000229
  23. Leiro, Victoria; Seco, Jose´ Manuel; Quin~oa´, Emilio; Riguera, Ricardo. "Assigning the Configuration of Amino Alcohols by NMR: A Single Derivatization Method". Organic Letters 10 13 (2008): 2733-2736. http://dx.doi.org/10.1021/ol800853u.
    10.1021/ol800853u
  24. Leiro, Victoria; Seco, Jose´ Manuel; Quin~oa´, Emilio; Riguera, Ricardo. "Cross Interaction Between Auxiliaries: The Chirality of Amino Alcohols by NMR". Organic Letters 10 13 (2008): 2729-2732. http://dx.doi.org/10.1021/ol8008528.
    10.1021/ol8008528
  25. Leiro, Victoria; Freire, Félix; Quiñoá, Emilio; Riguera, Ricardo. "Absolute configuration of amino alcohols by 1H-NMR". Chemical Communications 44 (2005): 5554. http://dx.doi.org/10.1039/b510806c.
    10.1039/b510806c
  26. Pazos, Yolanda; Leiro, Victoria; Seco, José M; Quiñoá, Emilio; Riguera, Ricardo. "Boc–phenylglycine: a chiral solvating agent for the assignment of the absolute configuration of amino alcohols and their ethers by NMR". Tetrahedron: Asymmetry 15 12 (2004): 1825-1829. http://dx.doi.org/10.1016/j.tetasy.2004.04.032.
    10.1016/j.tetasy.2004.04.032

Intellectual property

Patent
  1. Pêgo, Ana; Leiro, Victoria; Eduardo Fernandez-Megia; D. Ricardo Riguera Vega. 2020. "Biodegradable dendritic structure, methods and uses thereof". United States.
    Granted/Issued
  2. Pêgo, Ana Paula (8E1B-3F86-D97C); Leiro, Victoria (7713-0BE4-AC65); Fernandez Megia E; Riguera Vega R. 2017. "Biodegradable Dendritic Structure, Methods and Uses Thereof".
    Granted/Issued
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2024/02/03 "Research on Innovative Biodegradable Contrast Agents to Improve Accuracy in CT Stroke Diagnosis" (PT: "A investigação e os agentes de contraste inovadores e biodegradáveis para melhorar a precisão no diagnóstico de AVC em TC" Radiologia ao Centro - Knowledge Transforms Lives
Centro Hospitalar e Universitário de Coimbra (Coimbra, Portugal)
2023/11 Dendrimers as Alzheimer's Disease Nanotherapeutics ¿ Evidence of Antiamyloidogenic Properties Against Aß (1-42) 10th i3S Annual Meeting
(Portugal)
2023/11 The empire strikes back: Biodegradable dendrimers as delivery vectors of neuroprotective therapies for stroke 10th i3S Annual Meeting
(Portugal)
2023/09 The "shuttles" to neuroprotection: Biodegradable dendrimers as delivery vectors in the context of stroke ESB 2023 – 33rd Conference of the European Society for Biomaterials
(Davos, Switzerland)
2023/09 A new PNS-CNS-on-chip to explore the therapeutic potential of neuro-targeted trimethyl chitosan-based nanoparticles as a treatment for spinal cord injury 33rd Annual Conference of the European Society for Biomaterials
(Davos, Switzerland)
2023/04 Antimicrobial peptide-grafted PLGA-PEG Nanoparticles to Fight Bacterial Wound Infections Nanospain 2023
(Tarragona, Spain)
2022/12 Antimicrobial peptide-grafted PLGA-PEG Nanoparticles to Fight Bacterial Wound Infections International Conference for Young Scientists
(Slovakia)
2022/12 Biodegradable Dendrimers as Versatile Nanotherapeutics for Gene Therapy Applications BioTecJourney 2022
(Porto, Portugal)
2022/11 New Nanobiomaterials for Stroke Neuroprotection and Neurorecovery: A Novel Biodegradable Vector Applied In Vivo for mRNA Therapeutics XLIV Congreso de la Sociedad Ibérica de Biomecánica y Biomateriales
(Cáceres, Spain)
2022/10 Nanoparticles and Microfluidics: A Winning Combination to Design a Novel Targeted Vector 5th PhDay: "Building Paths: The Science Behind Us". Porto, Portugal
(Porto, Portugal)
2022/09 Biodegradable dendrimers for mRNA therapeutics: crossing the BBB of the ischemic brain 32nd Annual Conference of the European Society for Biomaterials (ESB 2022)
(France)
2022/06 A micro approach for a macroproblem: Pexiganan A-grafted microspheres to clear H. pylori infection SYMPOSIUM ON IMMUNOMODULATION IN CANCER AND REGENERATION, 4th edition
(Porto, Portugal)
2022/06 Exploring biodegradable dendrimers as carriers of neuroprotective therapeutics in the context of Stroke IX BiotechHealth Annual Symposium
(Portugal)
2022/06 Novel neurotargeted nucleic acid delivery vectors as a therapeutic tool to tackle neurological disorders
(Porto, Portugal)
2022/06 Exploring Fully Biodegradable Dendrimers as Nanocarriers for siRNA Delivery to Chondrocytes eCM20 Cartilage and Disc Repair and Regeneration
(Davos, Switzerland)
2022/05 Multifunctional Dendrimers as Therapeutics for Alzheimer's Disease Innovation in Doctoral Education
(Dublin, Ireland)
2021/11 A neuroprotective mRNA therapy: reaching the ischemic brain using biodegradable dendrimers 4th PhDay: Break borders and build opportunities
i3S - Instituto de Investigação e Inovação em Saúde (Porto, Portugal)
2021/09 Designing a new targeted dendritic nanosystem for nucleic aciddelivery to neuronal cells: the combination of fully biodegradable dendrimers and proteins 31st Conference of the European Society for Biomaterials ESB2021
(Porto, Portugal)
2021/09 Exploring a biodegradable dendrimer as carrier of neuroprotective mRNA to reach the ischemic brain 31st Conference of the European Society for Biomaterials ESB2021
(Porto, Portugal)
2021/09 Pexiganan-A grafted chitosan microparticles & Helicobacter pylori: a bitter love story 31st Conference of the European Society for Biomaterials ESB2021
(Porto, Portugal)
2021/09 The quest for survival in the highly proteolytic environment of a skin chronic wound: a case for efficient antimicrobial peptide conjugation 31st Conference of the European Society for Biomaterials ESB2021
(Porto, Portugal)
2021/06 Designing a new neurotargeted dendritic nanoparticle for nucleic acid delivery 4th Doctoral Congress in Engineering (DCE 2021)
Faculdade de Engenharia da Universidade do Porto (Porto, Portugal)
2021/06 Using fullybiodegradable dendrimers to deliver neuroprotective mRNA in Stroke 4th Doctoral Congress in Engineering (DCE 2021)
Faculdade de Engenharia da Universidade do Porto (Porto, Portugal)
2021/06 When dialysis gets ‘mesh’y: removal of adsorbed peptide from high molecular weight chitosan to yield a contact-killing biomaterial 4th Doctoral Congress in Engineering (DCE 2021)
Faculdade de Engenharia da Universidade do Porto (Porto, Portugal)
2021/05 Fully biodegradable PEG-dendrimers to act as efficient vectors of different siRNA sequences IJUP - 14ª edição do Encontro de Investigação Jovem da Universidade do Porto
Universidade do Porto (Porto, Portugal)
2021/05 AMP-PLGA Nanoparticles to Fight Bacterial Wound Infections IJUP - 14ª edição do Encontro de Investigação Jovem da Universidade do Porto
Universidade do Porto (Porto, Portugal)
2020/05/19 Fully biodegradable PEG-Dendrimers as efficient carriers for siRNA delivery World Biomaterials Congress 2020
(Glasgow, United Kingdom)
2020 Fatal attraction: chitosan microspheres decorated with MSI-78A kill Helicobacter pylori NanoPT 2020
(Portugal)
2020 Helicobacter pylori & MSI-78A antimicrobial peptide: a fatal attraction 3rd PhDay i3S
(Portugal)
2020 Antibiotic-Free Chitosan Microparticles for Helicobacter pylori infection management 11th World Biomaterials Congress 2020
(United Kingdom)
2020 Designing a new fully biodegradable dendritic nanosystem for targeted neuronal delivery 3rd PhDay | Back to the Future
(OPO, Portugal)
2019/09/25 PAMAM PEG-Dendrimers for neurotherapeutic delivery in stroke.1st Discoveries Forum on Regenerative and Precision Medicine 1st Discoveries Forum on Regenerative and Precision Medicine
(Porto, Portugal)
2019/09 A novel family of fully biodegradable PEG-dendrimers as efficient carriers for gene therapy 30th Annual Conference of the European Society for Biomaterials (ESB2019)
(Dresden, Germany)
2019/07 From Peripheral to Central Nervous System: A Journey Towards Targeted Neuronal Delivery IDS11 - 11th International Dendrimer Symposium
(Funchal, Madeira, Portugal)
2019/07 New fully biodegradable PEG-dendritic block copolymers: from synthesis to application as efficient nanocarriers of siRNA IDS11 - 11th International Dendrimer Symposium
(Funchal, Madeira, Portugal)
2019/03 New Fully Biodegradable Dendrimers as delivery vectors for gene therapy VII AEICBAS Biomedical Congress
(Porto, Portugal)
2019/03 nanoBiomaterials for Neurology: one (powerful) tool, many applications Tanja Weil Group Retreat
(Germany)
2019 Nano-enabled Systems for Nucleic Acid Delivery to the Nervous System 6th NanoToday Conference
(lisbon, Portugal)
2019 Delivery of nucleic acids in brain ischemia mediated by dendrimers: The challenge of crossing the blood-brain barrier VII ABC Biomedical Congress
(Portugal)
2019 Biodegradable dendrimer as nucleic acid delivery vector for neuronal cells 3rd Doctoral Congress in Engineering (DCE 2019)
(Portugal)
2018/11/30 Fully biodegradable PEG-dendrimers for nucleic acid delivery International Advisor Committee of the MAD-NANO18 Madeira International Conference, Emerging trends and future of Nanomaterials for Human Health
(Funchal, Madeira, Portugal)
2018/11 Fully Biodegradable PEG-Dendrimers: Synthesis and “click” functionalization to Act as Nucleic Acid Vectors 7th i3S Annual Meeting
(Póvoa do Varzim)
2018/11 Blood-Brain Barrier Transport and Neuronal Uptake of PAMAM Dendrimers after Focal Brain Ischemia 7th i3S Annual Meeting
(Póvoa do Varzim, Portugal)
2018/06 Fully Biodegradability of PEG-Dendritic Block Copolymers towards an efficient siRNA Delivery 6th International Symposium on Biomedical Applications of Dendrimers
(Urbino, Italy)
2018/05 On the Fully Biodegradability of PEG-Dendrimers for siRNA Delivery 12th International Symposium on Polymer Therapeutics: From Laboratory to Clinical Practice
(Valencia, Spain)
2018/02 Novel Fully Biodegradable PEG-dendrimers: promising carriers to siRNA delivery Encontro de Investigação Jovem da Universidade do Porto
(Porto, Portugal)
2018 Fully Biodegradable PEG-Dendrimers: Synthesis and "click" functionalization to Act as Nucleic Acid Vectors 7th i3S annual meeting
(Portugal)
2017/11 Novel biodegradable PEG-dendrimers as vehicles of siRNA International Symposium on Bioinspired Macromolecular Systems
(Aveiro, Portugal)
2017/11 Exploring new fully biodegradable PEG-Dendrimers as siRNA vectors 6th I3S Annual Meeting 2017
(Póvoa do Varzim, Portugal)
2017/09 Synthesis of biodegradable PEG-GATGE dendritic block copolymers to serve as siRNA vectors 28th European Conference on Biomaterials (ESB2017)
(Athens, Greece)
2017 On the biodegradability of PEG-Dendritic Block Copolymers for siRNA Delivery 6th China-Europe Symposium on Biomaterials in Regenerative Medicine CESB2017
(Portugal)
2016/11 Biodegradable PEG-GATGE dendritic block copolymers: synthesis and potential as siRNA vectors MAD–Nano16: Emerging Trends and Future of Nanomaterials for Human Health
(Funchal, Madeira, Portugal)
2016/05 Biodegradable Dendritic Structures: Synthesis and Biofunctionality Assessment as Nucleic Acid Vectors 11th International Symposium on Polymer Therapeutics: From Laboratory to Clinical Practice
(Valencia, Spain)
2016/05 On the biodegradability of PEG-Dendritic Block Copolymers for siRNA Delivery 6th China-Europe Symposium on Biomaterials in Regenerative Medicine CESB2017
(Porto, Portugal)
2014/01 Desing of Biodegradable GATG Dendrimers for DNA/RNA Delivery IV Encuentro sobre Dendrímeros EDEN 4
(Santiago de Compostela, Spain)
2014 Design of biodegradable GATG dendrimers for DNA/RNA delivery IV Encuentro Sobre Dendrímeros EDEN 4
(Spain)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2024/02 - Current Biodegradable dendritic contrast agents for brain imaging
Supervisor of Carolina Delgado Teixeira Pedro
 Biochemistry (Degree)
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2022/03/16 - Current MSc Research Assistant in the framework of the Project JumpIN (PTDC/BTM-MAT/4156/2021)
Supervisor
2021 - Current Design of dendrimer-based vectors for nucleic acid delivery to cartilaginous tissues of the joint and IVD (PhD Project/Grant Ref. 860151)
Co-supervisor
2020/01 - Current MSc Research Assistant in the framework of the Project siRNAC
Supervisor of Ana Isabel Moreira Jesus
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2020 - Current Multifunctional biodegradable dendrimers as therapeutics for Alzheimer's disease (PhD Grant Ref. UI/BD/150831/2021)
Co-supervisor
2019 - 2024 Neuron-targeted nanocarriers for siRNA delivery with potential for the treatment of neurological disorders (PhD Grant Ref. SFRH/BD/137073/2018).
Co-supervisor of Ana Patricia da Nave Spencer
 Engenharia Biomédica (PhD)
Universidade do Porto Faculdade de Engenharia, Portugal
2022/02 - 2022/10 Engineered hydrogel coating for improved biocompatibility of chronically-implanted neural electrodes
Co-supervisor
2021 - 2022/09 Synthesis and Evaluation of Biodegradable Diamine Terminated PEG-GATGE Dendrimers as Vectors for the Delivery of siRNA
Supervisor
2020/09 - 2021/10 Synthesis and Surface Engineering of biodegradable PEG-Dendrimers to act as efficient nanovehicles for the delivery of siRNA
Supervisor
2020/01/01 - 2020/03/31 MSc Research Assistant in the framework of the Project Baits
Supervisor of André Filipe Gonçalves de Carvalho
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Instituto Nacional de Engenharia Biomédica, Portugal
2019 - 2020 Exploring the potential of fully biodegradable PEG-Dendrimers as nanocarriers for dual delivery of siRNA
Supervisor of Maria Ana Nova Morais Gramaxo Gouveia
 Bioengenharia
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2019 - 2020 Development of point-of-care early infection diagnose through infection sensitive biomarkers multifunctionalization onto chitosan
Co-supervisor of Monica Lucena
 Bioengenharia
Universidade do Porto Faculdade de Engenharia, Portugal
2019/02 - 2019/12 MSc Research Assistant in the framework of the Project Baits
Supervisor of Sara Carolina Silva Reis
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Instituto Nacional de Engenharia Biomédica, Portugal
2018/09 - 2019/12 MSc Research Assistant in the framework of the Project siRNAC
Supervisor of Pedro Barbosa Mota
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Instituto Nacional de Engenharia Biomédica, Portugal
2018 - 2019 Exploring Fully Biodegradable PEG-dendrimers as Nucleic Acid Vectors Targeted to the Nervous System
Supervisor of Luís Carlos Oliveira Francisco
 Engenharia Biomédica
Universidade do Porto Faculdade de Engenharia, Portugal
2018/02 - 2018/12 MSc Research Assistant in the framework of the Projects: INFARMED - "nanoTerapias Neuroprotetoras avançadas para o tratamento de acidentes vasculares cerebrais" and "siRNAC - Novel siRNA Therapies against Metastatic Colorectal Cancer".
Supervisor of Ana Patrícia da Nave Spencer
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Instituto Nacional de Engenharia Biomédica, Portugal
2017/01 - 2018/12 MSc Research Assistant in the framework of the Project Baits
Supervisor of Natália Papadopolulos Magalhães
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Instituto Nacional de Engenharia Biomédica, Portugal
2018 - 2018 New Fully Biodegradable PEG Dendrimers to act as siRNA Vectors to the Nervous System
Supervisor of Cristiana Filipa Vieira de Sousa
 Bioquímica (Master)
Universidade do Porto Faculdade de Ciências, Portugal
2017 - 2018 Development of an injectable self-assembled bioactive hybrid hydrogel
Co-supervisor of Tânia Sofia de Sousa Magalhães Neto
 Bioengenharia
Universidade do Porto Faculdade de Engenharia, Portugal
2016 - 2017 New Fully Biodegradable PEG-Dendrimers: Synthesis and evaluation as siRNA vectors
Supervisor of Ana Patrícia da Nave Spencer
 Genética Molecular e Biomedicina (Master)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2016 - 2017 Delivery of Neurotrophins in Brain Ischemia
Co-supervisor of Simão Pedro Barbosa Teixeira
 Engenharia Biomédica
Universidade do Porto Faculdade de Engenharia, Portugal
2016 - 2017 Exploring biodegradable dendrimers as nucleic acid vectors
Supervisor of Giancarlo Grano
 Science in Materials Engineering and Nanotechnology
Faculty of Materials engineering and nanotechnology at University of Salento , Italy
2015 - 2015 Exploring  New Peg-Dendritic Block Copolymers as siRNA Delivery Vectors
Supervisor of João Pedro Marques Garcia
 Engenharia Biomédica (Master)
Universidade do Porto Faculdade de Engenharia, Portugal
2005 - 2006 Determinación de la configuración absoluta de ß-aminoalcoholes con un centro quiral en posición
Co-supervisor of Yuri Segade
 Quimica (Degree)
Universidad de Santiago de Compostela Departamento de Química Orgánica, Spain

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2021 - Current Volunteer in the Organizing Committee of the 31st Conference of the European Society for Biomaterials (ESB) and the 43rd Annual Congress of the Iberian Society of Biomechanics (2021/09)
Conference (Member of the Organising Committee)

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2014/06 - Current Volunteer in the exhibition “A Engenharia Biomédica num Quarteirão de Histórias” organized by INEB - Instituto de Engenharia Biomédica. Mercado do Bom Sucesso. Porto, Portugal.
Exhibition
2004/06 - Current "Introduction to Molecular Modelling” Course from Prof. Gerardo Burton
Universidade de Santiago de Compostela Facultade de Química, Spain
2024/02/03 - 2024/02/03 Participation in the Round Table about the Research on Innovative Biodegradable Contrast Agents to Improve Accuracy in CT Stroke Diagnosis
Round table
 Radiologia ao Centro - Knowledge Transforms Lives
Centro Hospitalar e Universitário de Coimbra EPE, Portugal
2023/10/17 - 2023/10/20 Academic session on "Fundamentals for a Successful Project" within the scope of the course "CaixaImpulse Health Innovation - Course on Tech Transfer Leadership in Life Sciences"
Workshop
 Fundamentals for a Successful Project
Pompeu Fabra University-Barcelona School of Management, Spain
2023/09/26 - 2023/09/29 Academic session on "Entrepreneurship" within the scope of the course "CaixaImpulse Health Innovation ¿ Course on Tech Transfer Leadership in Life Sciences"
Workshop
 "Entrepreneurship"
Pompeu Fabra University-Barcelona School of Management, Spain
2019/01 - 2019/01 ¿Nanotechnology for therapy and diagnostics¿. nanoGateway Winter School 2019. INL. Braga, Portugal.
International Iberian Nanotechnology Laboratory, Portugal
2015 - 2015 Volunteer in “13ª Mostra da Universidade do Porto. Informação, experimentação e descoberta”. Alfândega do Porto. Porto, Portugal
Universidade do Porto, Portugal
2014/06 - 2014/06 Workshop "Flow Cytometry - Fundamentals and applications". Porto, Portugal.
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal

Instituto Nacional de Engenharia Biomédica, Portugal
2012/05 - 2012/05 "Third I3S Scientific Retreat". Póvoa de Varzim, Portugal.
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2011 - 2011 Volunteer in “Jornada de Puertas abiertas”. Centro de Investigación en Química Biológica y Materiales Moleculares (CIQUS).
Universidade de Santiago de Compostela, Spain
2009/07 - 2009/07 “II Workshop on Nanomedicine Research”. Santiago de Compostela, Spain.
2008/11 - 2008/11 “I Jornada Gallega de Investigación en Nanomedicina”. Vigo, Spain.
2007 - 2008 Training course for operating with Bruker AMX 500 and Varian Inova 400 spectrometers
2007/11 - 2007/11 “Simposio Internacional – Nanotecnología en medicina: Diagnóstico y Terapia”. Vigo, Spain.
2005/06 - 2005/06 “Advanced Course in Nuclear Magnetic Resonance”. NMR Group of the Spanish Royal Society of Chemistry (RSEQ). Jaca –Huesca, Spain.
Spanish Royal Society of Chemistry, Spain
2004 - 2005 Teacher Training Course
Universidade de Santiago de Compostela, Spain
2003 - 2004 Training course for operating with Bruker DPX 250 and Varian Mercury 300 spectrometers.
2002 - 2004 Courses and seminars corresponding to the Doctorate Program in Organic Chemistry.
Universidad de Santiago de Compostela Departamento de Química Orgánica, Spain

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2023/09/20 MicroRNAs in Kidney-Heart Fibrosis Crosstalk
(Thesis) Main arguer
 Eduarda Carvalho Ferreira (Master)
Universidade do Porto, Portugal
2021/12/16 Anticancer prodrug nanoscale platform using low-generation dendrimers and/or platinum derivatives – Synthesis, cytotoxicity, and synergetic effects
(Thesis) Main arguer
 Cláudia Sofia Camacho (PhD)
Universidade da Madeira Centro de Química da Madeira, Portugal
2019/05/17 Heterofuncionalización de nanosistemas dendríticos de naturaleza carbosilano para su aplicación en biomedicina
(Thesis) Main arguer
 María Sánchez Milla (PhD)
Universidad de Alcalá de Henares Departamento de Química Orgánica y Química Inorgánica, Spain
2017/07/13 Antimicrobial silicones for use as dialysis catheters Ana Rita Noutel Lorga Gomes (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2017/05/23 Copolímeros de bloque PEG-Dendrímero para el transporte de fármacos Marcos Fernández Villamarín (PhD)
University of Santiago de Compostela- Centro de Investigación en Química Biolóxica e Materiais Moleculares, Spain

Committee member

Activity description
Role 		Institution / Organization
2021 - Current National Advisory Comitee Member at the 31th Conference of the European Society for Biomaterials ESB2021. Porto, Portugal.
Advisor / Consultant
2023/04 - 2023/09 Member of the Scientific Advisory Board ESB 2023 - 33rd Annual Conference of the European Society for Biomaterials
Advisor / Consultant
 AO Research Institute Davos, Switzerland

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2004 - 2006 60 hours/year in the teaching of the discipline "Experimentación en Química Orgánica" of the Graduation in Chemistry at the Departament of Organic Chemistry. (Licence) Universidad de Santiago de Compostela Departamento de Química Orgánica, Spain

Interview (newspaper / magazine)

Activity description Newspaper / Forum
2024/02/19 "¿Cómo mejorar la imagen de TAC para un diagnóstico más preciso y rápido del ictus?" Scientific Divulgation of the project "Smart dendritic contrast agent for accurate stroke diagnosis by computed tomography" La Vanguardia - Spanish daily newspaper
2023/10/18 Scientific divulgation to the society: "CaixaImpulse Innovation Program finances i3S project to improve stroke diagnosis"
2023/02/01 "When your degradation makes you smart!" New and interview about the scientific article "Versatile fully biodegradable dendritic nanotherapeutics" in the "i3S Editor¿s Choice" section of the public Newsletter of i3S - Instituto de Investigação e Inovação em Saúde da Universidade do Porto. i3S Newsletter Public
2007/12/14 Una monterrosina acabó Químicas con un solo aprobado La voz de Galicia

Interview (tv / radio show)

Program Topic
2024/02/09 - 2033/02/12 90 segundos de Ciência (90 seconds of Science) Ciência
2018/05 - 2018/05 Radio television de Galicia

Journal scientific committee

Journal title (ISSN) Publisher
2022/09 - Current Frontiers in Pharmacology (1663-9812) Frontiers Editorial
2021 - Current Advances in Colloid and Interface Science (0001-8686) Elsevier Editorial
2021 - Current Pharmaceutics (1999-4923) MDPI Editorial
2021 - Current Molecules (1420-3049) MDPI Editorial
2021 - Current Frontiers in Chemistry (2296-2646) Frontiers Editorial
2021 - Current Frontiers in Bioengineering and Biotechnology (2296-4185) Frontiers Editorial
2020 - Current Biomaterials (0142-9612) Elsevier
2020 - Current Pharmaceuticals (1424-8247) MDPI
2019 - Current Journal of Organometallic Chemistry (0022-328X) Elsevier
2019 - Current RSC Advances (2046-2069) The Royal Society of Chemistry
2019 - Current Colloids and Surfaces B Biointerfaces (0927-7765) Elsevier
2017 - Current European Journal of Pharmaceutical Sciences (0928-0987) Elsevier
2017 - Current Current Gene Therapy (1566-5232) Bentham Science

Mentoring / Tutoring

Topic Student name
2020 - Current Nanomedicine for stroke: polymeric carriers of neurotherapies towards the diseased brain. Neurobiology Master. Faculdade de Medicina, Universidade do Porto, Portugal Ricardo Gil Santos Mota
2019 - Current DETOX: an innovative neuroprotective nanosystem for the treatment of cerebrovascular accidents. International Doctoral Programme in Molecular and Cellular Biotechnology Applied to Health Sciences. Universidade do Porto and ICBAS Marília Torrado
2021/10 - 2022/02 Project of Biodesign of the discipline Biodesign Innovation, Economy and Management entitled "Dendrimers for Nucleic Acid Delivery in Stroke", Master in Biomedical engineering from Faculty of Engineering, UP Rafael Santos
2021/10 - 2022/02 Project of Biodesign of the discipline Biodesign Innovation, Economy and Management entitled "Dendrimers for Nucleic Acid Delivery in Stroke", Master in Biomedical engineering from Faculty of Engineering, UP Nuno Oliveira
2021/10 - 2022/02 Project of Biodesign of the discipline Biodesign Innovation, Economy and Management entitled "Dendrimers for Nucleic Acid Delivery in Stroke", Master in Biomedical engineering from Faculty of Engineering, UP Raquel Pereira
2021/10 - 2022/02 Project of Biodesign of the discipline Biodesign Innovation, Economy and Management entitled "Dendrimers for Nucleic Acid Delivery in Stroke", Master in Biomedical engineering from Faculty of Engineering, UP Inês Vilela de Sousa
2019 - 2020 “Engineering Precision Bionanotheranostics”. PhD student from Max Planck Institute for Polymer Research (MPI-P) at Mainz, Germany. Yingke Wu
2019 - 2020 Delivery of Neuroprotective Nanoparticles in Brain Ischemia. Biochemistry Master. Faculdade de Ciências, Universidade do Porto,Portugal Joana Filipa Moreira
2018 - 2019 Delivery Of Neuroprotective Nanoparticles In Brain Ischemia. Biomedical Engineering Master. Faculdade de Engenharia, Universidade do Porto, Portugal Diana Bola
2017 - 2018 Project of Biodesign of the discipline Biodesign Innovation, Economy and Management entitled "Biodegradable dendrimers for nucleic acid (siRNA) delivery", Master in Biomedical engineering from Faculty of Engineering, UP Ana Cançado
2017 - 2018 Project of Biodesign of the discipline Biodesign Innovation, Economy and Management entitled "Biodegradable dendrimers for nucleic acid (siRNA) delivery", Master in Biomedical engineering from Faculty of Engineering, UP Ana Castro
2017 - 2018 Project of Biodesign of the discipline Biodesign Innovation, Economy and Management entitled "Biodegradable dendrimers for nucleic acid (siRNA) delivery", Master in Biomedical engineering from Faculty of Engineering, UP Catarina Coelho
2017 - 2018 Project of Biodesign of the discipline Biodesign Innovation, Economy and Management entitled "Biodegradable dendrimers for nucleic acid (siRNA) delivery", Master in Biomedical engineering from Faculty of Engineering, UP Gabriela Caldas
2017 - 2018 Project of Biodesign of the discipline Biodesign Innovation, Economy and Management entitled "Biodegradable dendrimers for nucleic acid (siRNA) delivery", Master in Biomedical engineering from Faculty of Engineering, UP Helena Gomes
2017 - 2018 Project of Biodesign of the discipline Biodesign Innovation, Economy and Management entitled "Biodegradable dendrimers for nucleic acid (siRNA) delivery", Master in Biomedical engineering from Faculty of Engineering, UP Renato Carvalho
2016 - 2017 Project of Molecular Bioengineering of the discipline Molecular Biotechnology entitled "Biodendrons - Better diagnosis of Parkinson’s disease – a new window of treatment", Integrated Master in Bioengineering from Faculty of Engineering, UP Ana Ribeiro
2016 - 2017 Project of Molecular Bioengineering of the discipline Molecular Biotechnology entitled "Biodendrons - Better diagnosis of Parkinson’s disease – a new window of treatment", Integrated Master in Bioengineering from Faculty of Engineering, UP Ana Martins
2016 - 2017 Project of Molecular Bioengineering of the discipline Molecular Biotechnology entitled "Biodendrons - Better diagnosis of Parkinson’s disease – a new window of treatment", Integrated Master in Bioengineering from Faculty of Engineering, UP Catarina Coutinho
2016 - 2017 Project of Molecular Bioengineering of the discipline Molecular Biotechnology entitled "Biodendrons - Better diagnosis of Parkinson’s disease – a new window of treatment", Integrated Master in Bioengineering from Faculty of Engineering, UP Débora Moreira
2016 - 2017 Project of Molecular Bioengineering of the discipline Molecular Biotechnology entitled "Biodendrons - Better diagnosis of Parkinson’s disease – a new window of treatment", Integrated Master in Bioengineering from Faculty of Engineering, UP Inês Pereira
2016 - 2017 Project of Molecular Bioengineering of the discipline Molecular Biotechnology entitled "Biodendrons - Better diagnosis of Parkinson’s disease – a new window of treatment", Integrated Master in Bioengineering from Faculty of Engineering, UP Nelson Leça
2012 - 2017 Effect of industrial GMP human plasma derived supplement on hMSC behavior. IB2 - Industrial Biological Biomaterials Doctorate. Marie Curie Initial Training Networks: European Industrial Doctorates, FP7-PEOPLE-2012-ITN (317052) Maura Cimino
2016 - 2016 “Physicochemical characterization of siRNA dendriplexes”. Degree student in Biochemistry at the Faculty of Science and Instituto de Ciências Biomédicas Abel Salazar at University of Porto. Raquel Sofia Vaz
2015 - 2016 Project of Molecular Bioengineering of the discipline Molecular Biotechnology entitled "Dendronic: a biodegradable dendrimer-based contrast agent for Magnetic Resonance Imaging (MRI)" Integrated Master in Bioengineering from Faculty of Engineering, UP Ana Elisa Sousa
2015 - 2016 Project of Molecular Bioengineering of the discipline Molecular Biotechnology entitled "Dendronic: a biodegradable dendrimer-based contrast agent for Magnetic Resonance Imaging (MRI)" Integrated Master in Bioengineering from Faculty of Engineering, UP Elsa Silva
2015 - 2016 Project of Molecular Bioengineering of the discipline Molecular Biotechnology entitled "Dendronic: a biodegradable dendrimer-based contrast agent for Magnetic Resonance Imaging (MRI)", Integrated Master in Bioengineering from Faculty of Engineering, UP Inês Borges
2015 - 2016 Project of Molecular Bioengineering of the discipline Molecular Biotechnology entitled "Dendronic: a biodegradable dendrimer-based contrast agent for Magnetic Resonance Imaging (MRI)", Integrated Master in Bioengineering from Faculty of Engineering, UP Joana Silva
2015 - 2016 Project of Molecular Bioengineering of the discipline Molecular Biotechnology entitled "Dendronic: a biodegradable dendrimer-based contrast agent for Magnetic Resonance Imaging (MRI)", Integrated Master in Bioengineering from Faculty of Engineering, UP Luis Baptista
2015 - 2016 Project of Molecular Bioengineering of the discipline Molecular Biotechnology entitled "Dendronic: a biodegradable dendrimer-based contrast agent for Magnetic Resonance Imaging (MRI)", Integrated Master in Bioengineering from Faculty of Engineering, UP Sara Sousa

Other jury / evaluation

Activity description Institution / Organization
2023/10 - Current Jury member for selection of a MSc Research Assistant for a position (Fellow_BI/FCT_Proj2021/i3S/18013101/2023 ) in the context of the JUmpIN project ( HiJacking the peripheral neurons retrograde trafficking machinery to deliver neUroprotective Molecules to sPinal cord InterNeurons - PTDC/BTM-MAT/4156/2021). Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2023/03 - Current Jury member for selection of a MSc Research Assistant for a position (Fellow_BI/FCT_Proj2021/i3S/24020903/2023 ) in the context of the JUmpIN project ( HiJacking the peripheral neurons retrograde trafficking machinery to deliver neUroprotective Molecules to sPinal cord InterNeurons - PTDC/BTM-MAT/4156/2021). Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2016 - Current Jury member for selection of MSc Research Assistants in different projects at i3S/INEB. Instituto Nacional de Engenharia Biomédica, Portugal

Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2022/05 - 2022/05 Jury member for selection of a MSc Research Assistant for a position (BIM/FCT_ Proj2021/i3S/08042204/2022 ) in the context of the BioCoat project ( Engineered biomimetic hydrogel coating for improved biocompatibility of chronically-implanted neural electrodes - EXPL/BTM-MAT/1499/2021). Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2022 - 2022 Jury member for selection of a MSc Research Assistant for a position (BI/FCT_Proj2021/i3S/13012601/2022 ) in the context of the JumpIN project ( “JumpIN - HiJacking the peripheral neurons retrograde trafficking machinery to deliver neUroprotective Molecules to sPinal cord InterNeurons - PTDC/BTM-MAT/4156/2021). Instituto Nacional de Engenharia Biomédica, Portugal

Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2020/11 - 2021/01 Jury member for selection of a PhD Position. H2020-Marie Sklodowska-Curie actions -ITN
2021 - 2021 Jury member to select abstract for oral and poster communications at 31th Conference of the European Society for Biomaterials ESB2021. Porto, Portugal and 43rd Annual Congress of the Iberian Society of Biomechanics and Biomaterials (SIBB)
2020 - 2020 Jury member to award the best oral communications in the 11th World Biomaterials Congress 2020. Glasgow, UK (virtual congress).
2019 - 2019 Jury member for selection of a MSc Research Assistant for a position (BAITS_BI_01_2019) in the context of the BaiTS project (“BaiTS - Biodegradable dendrimers for Targeted neuroprotective therapies in Stroke” - PTDC/CTM-NAN/3547/2014; POCI-01-0145-FEDER016639). Instituto Nacional de Engenharia Biomédica, Portugal

Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2019 - 2019 Jury member for selection of a MSc Research Assistant for a position (SIRNAC_BIM_01_2019) in the context of the SIRNAC project (“SIRNAC - NOVEL siRNA THERAPIES AGAINST METASTATIC COLORECTAL CANCER” - Proj, Nº 33399, NORTE-01-0247-FEDER-033399) Instituto Nacional de Engenharia Biomédica, Portugal

Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2019 - 2019 Jury member for selection of a MSc Research Assistant for a position (BAITS_BIM_01_2019) in the context of the BaiTS project (“BaiTS - Biodegradable dendrimers for Targeted neuroprotective therapies in Stroke” - PTDC/CTM-NAN/3547/2014; POCI-01-0145-FEDER016639) Instituto Nacional de Engenharia Biomédica, Portugal

Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2018 - 2018 Jury member for selection of a MSc Research Assistant for a position (NanoProtetor_BIM_01_2018) in the context of the project “nanoTerapias Neuroprotetoras avançadas para o tratamento de acidentes vasculares cerebrais” (nº FIS-FIS-2015-01_CCV_20150630-88). Instituto Nacional de Engenharia Biomédica, Portugal

Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2018 - 2018 Jury member for selection of a MSc Research Assistant for a position (BAITS_BI_01_2018) in the context of the BaiTS project (“BaiTS - Biodegradable dendrimers for Targeted neuroprotective therapies in Stroke” - PTDC/CTM-NAN/3547/2014; POCI-01-0145-FEDER016639) Instituto Nacional de Engenharia Biomédica, Portugal

Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2018 - 2018 Jury member for selection of a MSc Research Assistant for a position (SIRNAC_BIM_01_2018) in the context of the SIRNAC project (“SIRNAC - NOVEL siRNA THERAPIES AGAINST METASTATIC COLORECTAL CANCER” - Proj, Nº 33399, NORTE-01-0247-FEDER-033399). Instituto Nacional de Engenharia Biomédica, Portugal

Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2018 - 2018 Jury member for selection of a MSc Research Assistant for a position (BAITS_BIM_02_2018) in the context of the BaiTS project (“BaiTS - Biodegradable dendrimers for Targeted neuroprotective therapies in Stroke” - PTDC/CTM-NAN/3547/2014; POCI-01-0145-FEDER016639). Instituto Nacional de Engenharia Biomédica, Portugal

Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2017 - 2017 Jury member to select abstract for oral and poster communications at the 6th China-Europe Symposium on Biomaterials in Regenerative Medicine CESB2017. Porto, Portugal
2017 - 2017 Jury member for selection of a MSc Research Assistant for a position (NanoProtetor_BI_01_2016) in the context of the project “nanoTerapias Neuroprotetoras avançadas para o tratamento de acidentes vasculares cerebrais” (nº FIS-FIS-2015-01_CCV_20150630-88) Instituto Nacional de Engenharia Biomédica, Portugal

Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2016 - 2016 Jury member for selection of a MSc Research Assistant for a position (BAITS_BI_01_2016) in the context of the Baits Project (BaiTS - Biodegradable dendrimers for Targeted neuroprotective therapies in Stroke” - PTDC/CTM-NAN/3547/2014; POCI-01-0145-FEDER-016639). Instituto Nacional de Engenharia Biomédica, Portugal

Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2016 - 2016 Jury member for selection of a MSc Research Assistant for a position (BAITS_BI_02_2016) in the context of the BaiTS project ("BaiTS - Biodegradable dendrimers for Targeted neuroprotective therapies in Stroke” - PTDC/CTM-NAN/3547/2014; POCI-01-0145-FEDER016639) Instituto Nacional de Engenharia Biomédica, Portugal

Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Distinctions

Award

2023 Co-author: Marília Torrado was awarded with the best poster presentation award "Engineering Botulinum Neurotoxins towards an innovative neuroprotective nanosystem in the context of stroke" at the ETOX 2023 - European Workshop on Bacterial. Scotland
2022 Co-author (penultimate author): Débora Moreira was awarded with the best oral presentation award "Multifunctional Dendrimers as Therapeutics for Alzheimer's Disease" at the Innovation in Doctoral Education. Dublin, Ireland
2022 Co-author (penultimate author): Ana Patrícia Spencer was awarded with the best oral communication award "Nanoparticles and Microfluidics: A Winning Combination to Design a Novel Targeted Vector" at the 5th PhDay: "Building Paths: The Science Behind Us"
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2021 Co-author (penultimate author): Ana Spencer was awarded with the 1st place with the oral communication award "Designing a new neurotargeted dendritic nanoparticle for nucleic acid delivery" at the DCE 21 - Symposium on Biomedical Engineering. Porto, PT
Universidade do Porto, Portugal
2021 Co-author (2nd author): Marília Torrado was awarded with the 1st place with the oral communication "A neuroprotective mRNA therapy: reaching the ischemic brain using biodegradable dendrimers". 4th PhDay - Break borders, build opportunities. i3S, Porto, PT
Universidade do Porto, Portugal
2020 Co-authorship: Diana Fonseca awarded 1st place at the 33rd Workshop of the European Helicobacter and Microbiota Study Group (virtual congress due to Covid19 pandemic), Vienna, Austria
2020 Co-authorship (2nd author): Marília Torrado was awarded with the 1st place with the poster "Tackling the beginnings of DETOX: an innovative neuroprotective nanosystem" in the Neurosciences category, at the 3rd PhDay: Back to the Future. Porto, Portugal
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2019 Co-authorship work (penultimate author): Ana Spencer awarded 4th place at the ABC Scientific Competition, Porto, Portugal
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2016 Granted a Postdoctoral Scholarship "Bolsa de Pós-Doutoramento (BPD)" from INEB/i3S. Structured Programme on Bioengineering Therapies for Infectious Diseases and Tissue Regeneration Project (NORTE-01-0145-FEDER-000012) in the frame of Norte2020
Norte2020 - Programa Operacional Regional do Norte, Portugal
2016 Travel Grant for the 11th International Symposium Polymer Therapeutics. CIPF- Centro de Investigación Príncipe Felipe, Valencia
Centro de Investigacion Principe Felipe, Spain
2010 Granted a Postdoctoral Scholarship "Bolsa de Pós-Doutoramento (BPD)" (grant ref. SFRH/BPD/69110/2010)
Fundação para a Ciência e a Tecnologia, Portugal
2008 Publication of two articles "back to back" in the Organic Letters journal of the American Chemical Society
American Chemical Society, United States
2007 Ph.D. with Quality Award
Ministry of Education and Science, Spain
2003 "Premio Extraordinario de Licenciatura en Química 2002/2003", prize awarded to the most outstanding postgraduate (Bc and Thesis) in Chemistry
Universidade de Santiago de Compostela, Spain
2003 "Premio de Licenciatura", prize awarded to the most outstanding Chemistry graduate (27560)
Government of Monterroso - Lugo, Spain
2003 Granted a Ph.D Scholarship "Formación de Profesorado Universitario (FPU)" (grant ref. AP2002-0611), FPU is an excellence grant for best PhD students based on marks as undergraduate
Ministry of Education, Culture and Sport, Spain
2002 "Premio extraordinario fin de carrera 2002 de la Comunidad Autónoma de Galicia", prize awarded to the most outstanding graduate in Chemistry of the Autonomous Community of Galicia in the year 2002.
Government of Galicia (Xunta de Galicia), Spain
2002 Granted a Master-Scholarship
Government of Galicia (Xunta de Galicia), Spain
2001 Granted a Collaboration-Scholarship for collaboration with the Departament of Organic Chemistry, University of Santiago de Compostela
Ministry of Education, Culture and Sport, Spain

Other distinction

2023 First and senior corresponding author of the "Versatile fully biodegradable dendritic nanotherapeutics" published in Biomaterials 2022 (10.1016/j.biomaterials.2021.121356), research article highlighted as the five better research articles in 2022 from i3S
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal