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Diana Dias Silva (DDS) is a Lecturer at Escola Superior de Saúde, Instituto Politécnico do Porto (ESS|P.Porto) and a Research Associate at the LAQV-REQUIMTE, Portugal, who possesses a well-established curriculum on experimentation and teaching in the field of Toxicology, Pharmacology and Forensic Sciences. She was born in 1983, and since 2007 holds a 6-year PharmD degree granted by FFUP with a final classification of 16/20 (Grade A). In 2009, after finishing the Specialization Course in Forensic Sciences of the Faculty of Medicine of the University of Porto (FMUP), Portugal, she was awarded with an FCT fellowship to carry out her doctoral studies at The Laboratory of Toxicology of FFUP and at The Centre for Toxicology of the UCL London (UK). During her PhD, DDS focused on the study of toxicodynamic and toxicokinetic interactions of amphetamines. In 2013, she obtained her PhD in Forensic Sciences by FMUP, with honour and distinction, and in the same year awarded the European PhD by Rector Dispatch. She successfully completed 4 Postdoctoral projects in Clinical, Analytical and Forensic Toxicology. DDS develops scientific and academic activity in the areas of Toxicology and Pharmacology of Psychoactive Substances, Pharmaceuticals, Environmental Carcinogens and Nanoparticles (preclinical, clinical and forensic aspects). She has experience in the teaching >50 Curricular Units of several graduation, MSc and PhD courses. DDS is/was a scientific supervisor of PhD students (11 ongoing), MSc students (21 completed; 1 ongoing), Integrated Master students (9 completed), Bachelor students (6 completed), and Mobility students (13 completed); and was a juror in 53 academic MSc and PhD examinations. She was member of several national and international Committees for Evaluation of Research Projects submitted for funding (including the Czech Science Foundation and UKRI-UK Research and Innovation) and a consultant for 3 pharmaceutical companies. She is member of the Direction of the Portuguese Association of Forensic Sciences (APCF). She was manuscript referee for >30 indexed scientific journals (ISI), edited the Special Issues "Insights into the Pharmacology, Toxicology and Clinical Applications of Hallucinogens" [JCM; IF 3.303] and "Psychoactive Substances in Neuronal Development" [Int J Mol Sci; IF 4.183], since 2020, is Editorial Board Member of Current Forensic Science (Bentham Science Publishers) and Psychoactives (MDPI), among others. DDS integrated the teams of 2 EU-commissioned Open Access Educational Projects, i.e., TOX-OER (www.toxoer.com) and Erasmus+OEMONOM; and of several funded projects - DDS worked as a team member or PI in 25 funded projects (9 international) and has been in strike collaboration with several national and international research groups. DDS presented her research in >50 (inter)national conferences (Portugal, USA, France, Germany, Spain, Sweden, among others) with >70 oral communications and >110 posters. DDS co-authors 50 abstracts and 63 articles (being corresponding/first/last author of 95%, representing more than 6,972 citations according to Scopus; h-index of 24) published in prestigious ISI-indexed international journals, in top journals (mostly Q1) in the field.
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Identification

Personal identification

Full name
Diana Cristina Dias da Silva
Date of birth
1983/06/25
Gender
Female

Author identifiers

Ciência ID
7715-CF06-F0B5
ORCID iD
0000-0002-7331-9157

Email addresses

  • dsilva@ff.up.pt (Professional)
  • diana.silva@apcforenses.org (Professional)
  • dds@ess.ipp.pt (Professional)

Addresses

  • UCIBIO-Research Unit on Applied Molecular Biosciences, Laboratory of Toxicology, Department of Biological Sciences, Faculty of Pharmacy of the University of Porto. Rua Jorge Viterbo Ferreira, 228, 4050-313, Porto, Porto, Portugal (Professional)
  • TOXRUN – Toxicology Research Unit, Department of Sciences, University Institute of Health Sciences (IUCS-CESPU), Rua Central de Gandra, 1317, 4585-116 , Gandra, Paredes, Portugal (Professional)

Websites

Knowledge fields

  • Medical and Health Sciences - Basic Medicine - Toxicology
  • Medical and Health Sciences - Other Medical Sciences - Forensic Science
  • Medical and Health Sciences - Basic Medicine - Pharmacology and pharmacy
Education
Degree Classification
2013/07/19
Concluded
 Forensic Sciences (Doutoramento)
Universidade do Porto Faculdade de Medicina, Portugal
"STUDY OF THE TOXICOLOGICAL INTERACTIONS BETWEEN AMPHETAMINE DESIGNER DRUGS IN THE CONTEXT OF POLYDRUG ABUSE" (THESIS/DISSERTATION)
 Approved with Distinction and Honour (summa cum la
2007/07/24
Concluded
 Pharmaceutical Sciences (6-year degree) (Licenciatura)
Universidade do Porto Faculdade de Farmácia, Portugal
"N/A" (THESIS/DISSERTATION)
 16/20 (Grade A)
Affiliation

Science

Category
Host institution 		Employer
2019/01 - 2021/06 Contracted Researcher (Research) REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
2013/10/01 - 2018/12/31 Postdoc (Research) Universidade do Porto Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares, Portugal
2009 - 2013 Researcher (Research) Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal
2011 - 2012 Visiting Researcher (Research) Brunel University Institute for the Environment Health and Societies, United Kingdom
2009 - 2011 Visiting Researcher (Research) University College London School of Pharmacy, United Kingdom

Teaching in Higher Education

Category
Host institution 		Employer
2024/02 - Current Adjunct Teacher (Polytechnic Teacher) Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
2021/02 - 2024/02 Invited Adjunct Teacher (Polytechnic Teacher) Instituto Politécnico de Leiria Escola Superior de Saúde, Portugal
2018 - 2024/02 Visiting Professor (University Teacher) Universidade do Porto Faculdade de Medicina, Portugal
2016/09 - 2024/02 Invited Assistant Professor (University Teacher) Instituto Universitário de Ciências da Saúde, Portugal
2020/12/01 - 2021/07/31 Invited Assistant (University Teacher) Universidade do Porto Faculdade de Farmácia, Portugal
2011 - 2012 Invited Assistant (University Teacher) Brunel University Institute for the Environment Health and Societies, United Kingdom
Projects

Grant

Designation Funders
2013 - 2015 Toxicological properties and biodistribution of nanomaterials of current technological interest
INCENTIVO_EQB_LA0006
Post-doc Fellow
Universidade do Porto Faculdade de Farmácia, Portugal
Concluded

Contract

Designation Funders
2024 - Current Perfil de segurança e potencial terapêutico da psilocibina e outros compostos de Psilocybe spp. no tratamento da depressão: Estudo pré-clínico
COMPETE2030-FEDER-00813300
Researcher
Cooperativa de Ensino Superior Politécnico e Universitário CRL, Portugal
 Fundação para a Ciência e a Tecnologia
Submitted
2023/12 - Current Study of the neuronal and epigenetic effects of psilocybin, psilocin, LSD, 5-MeO-DMT and mescaline
EpiNeuro
Instituto Universitário de Ciências da Saúde, Portugal

Cooperativa de Ensino Superior Politécnico e Universitário CRL, Portugal
Cooperativa de Ensino Superior Politécnico e Universitário CRL
Ongoing
2023/12 - Current Antidepressant potential and toxicity induced by psilocybin and magic mushrooms administration in rats
PsiloTox
Instituto Universitário de Ciências da Saúde, Portugal

Cooperativa de Ensino Superior Politécnico e Universitário CRL, Portugal
Cooperativa de Ensino Superior Politécnico e Universitário CRL
Ongoing
2023 - Current Avaliação de mecanismos celulares, bioqui´micos e moleculares na neurotoxicidade de inseticidas e herbicidas
CNPq/MCTI No 10/2023
Researcher
Conselho Nacional de Desenvolvimento Científico e Tecnológico
Submitted
2020 - Current Avaliação dos mecanismos moleculares responsáveis por psicoses induzidas por Canabinóides Sintéticos: foco nos processos cruciais da modulação do neurodesenvolvimento
PTDC/SAU-TOX/3078/2020
Researcher
Fundação para a Ciência e a Tecnologia
Not funded
2019/05/01 - Current Fapergs 05/2019 - Evaluation of biochemical and molecular mechanisms related to neurotoxicity of neonicotinoid insecticides and herbicides used in RS
898-UFRGS
Post-doc
Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul
Ongoing
2017 - Current Drug-induced toxicity. The role of cholesterol accumulation in non-alcoholic steatohepatitis and other related morbidities
SAICT-45-2017-02/31471
Co-Principal Investigator (Co-PI)
Fundação para a Ciência e a Tecnologia
Not funded
2014 - Current Combination effects between amphetamine-type stimulants and licit substances often consumed simultaneously, including legal highs, ethanol, caffeine, and tobacco. Development of experimental models for mixture toxicity assessment
PTDC/DTP-FTO/6714/2014
Co-Principal Investigator (Co-PI)
Fundação para a Ciência e a Tecnologia
Not funded
2024 - 2026 Avaliação de mecanismos celulares, bioquímicos e moleculares na neurotoxicidade de inseticidas e herbicidas
CNPq/MCTI No 10/2023
Researcher
Conselho Nacional de Desenvolvimento Científico e Tecnológico
2022 - 2026 The impact of electronic cigarettes and heated tobacco products on human health: A toxicometabolomics approach
BD/CBAS/CESPU/03/2022
Supervisor
Instituto Universitário de Ciências da Saúde, Portugal
 Instituto Universitário de Ciências da Saúde
2022 - 2026 New psychoactive substances: estimation of consumption by wastewater-based epidemiology and evaluation of their (eco)toxicity depression
2021.04999.BD
Supervisor
Fundação para a Ciência e a Tecnologia, Portugal
 Fundação para a Ciência e a Tecnologia
2021 - 2025 Untangling psilocybin’s pharmacology, toxicity, epigenetics and gut microbiome impact: One step closer to a new antidepressant drug
2021.04999.BD
Supervisor
Fundação para a Ciência e a Tecnologia
Ongoing
2020/12/01 - 2024/11/30 Unravelling the mechanisms of cannabinoid-induced epigenetic modifications associated to aging and age-related neurodegeneration
2020.04493.BD
Supervisor
Fundação para a Ciência e a Tecnologia
Ongoing
2020/12/01 - 2024/11/30 Assessment of the impact of Synthetic Cannabinoids in the neuron-glia cell communication during neuronal development
2020.07154.BD
Supervisor
Fundação para a Ciência e a Tecnologia
Ongoing
2020/02/01 - 2024/01/31 New trends in the drug misuse scene: untangling the toxicokinetic and toxicogenetic interactions of novel psychedelic club mixtures
BD/CBAS/CESPU/03/2020
Supervisor
Instituto Universitário de Ciências da Saúde, Portugal
 Instituto de Investigação e Formação Avançada em Ciências e Tecnologias da Saúde
Ongoing
2021/01/01 - 2024/01/01 Pharmacology and pharmacokinetics of psilocybin
Eurox Pharma
Co-Principal Investigator (Co-PI)
Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
 EUROX GROUP GMBH
Ongoing
2020/09/01 - 2023/08/31 OEMONOM – Open access Educational Materials On Naturally Occurring Molecules - sources, biological activity and use
2020-1-CZ01-KA203-078218
Technical development
Erasmus Plus
Ongoing
2022 - 2022 Safety profile and therapeutic potential of psilocybin and other Psilocybe mushrooms' phytochemicals for the treatment of depression: A preclinical study
2022.02020.PTDC
Co-Principal Investigator (Co-PI)
Fundação para a Ciência e a Tecnologia
Not funded
2022 - 2022 I.SEA.YEAST - A sustainable biotechnological concept for Iodine Deficiency Disease prevention combining edible seaweeds and brewer´s spent yeast biomass
2022.05959.PTDC
Researcher
Fundação para a Ciência e a Tecnologia
Not funded
2022 - 2022 Living in the era of antidepressants: combining metabolomics and behavioral approaches as a new paradigm for risk assessment of psychoactive pharmaceuticals in the aquatic environment
2022.01488.PTDC
Researcher
Fundação para a Ciência e a Tecnologia
Not funded
2022 - 2022 Unravelling new analgesic drugs: the therapeutic potential of krokodil morphinans
2022.05468.PTDC
Researcher
Fundação para a Ciência e a Tecnologia
Not funded
2022 - 2022 Can we otimize methotrexate central nervous system exposure in hematologic patients? A prospetive study designed to high dose methotrexate otimization
2022.07371.PTDC
Researcher
Fundação para a Ciência e a Tecnologia
Not funded
2022 - 2022 Development of bi-functional and safe cellulose-based packaging with combined zinc oxide-olive leaf extract-rosin
2022.10349.PTDC
Researcher
Fundação para a Ciência e a Tecnologia
Not funded
2021 - 2022 PsiloPharm: Psilocybin as a new alternative for the treatment of depression: unraveling the pharmacology, toxicokinetics and impact on the rat microbiome
UI&D IINFACTS 2021
Principal investigator
Instituto Universitário de Ciências da Saúde, Portugal
 Instituto de Investigação e Formação Avançada em Ciências e Tecnologias da Saúde
2019/09/07 - 2021/10/06 Fapergs 04/2019 – ARD Aid – Evaluation of herbicide immunotoxicity
Fapergs 04/2019
Researcher
Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul
Ongoing
2018/10 - 2021/09 PAHMIX: Mixtures of Environmental Carcinogens: a molecular approach to improve environmental risk assessment strategies
PTDC/CTA-AMB/29173/2017
Researcher
FCT [COMPETE 2020 - Operational Program for Competitiveness and Internationalization (OPCI)]
2018/07 - 2021/06 NEUROSCANN: Assessment of the modulatory effects of Synthetic CANNabinoids on NEUROnal development
PTDC/SAU-TOX/29584/2017
Post-doc
FCT [COMPETE 2020 - Operational Program for Competitiveness and Internationalization (OPCI)]
2021 - 2021 Viver na era dos antidepressivos: combinação de abordagens metabolómicas e comportamentais como um novo paradigma para avaliação de risco de fármacos psicoativos no ambiente aquático
PTDC/CTA-AMB/0138/2021
Researcher
Fundação para a Ciência e a Tecnologia
2021 - 2021 Biomateriais híbridos contendo nanotubos de argila haloisite para aplicações sustentáveis na pele
PTDC/BTM-MAT/1879/2021
Researcher
Fundação para a Ciência e a Tecnologia
Not funded
2021 - 2021 Esclerose múltipla: disfunção mitocondrial em axónios desmielinizados e papel da inibição das desacetilases de histonas na melhoria da função das organelas
EXPL/MED-NEU/0648/2021
Co-Principal Investigator (Co-PI)
Fundação para a Ciência e a Tecnologia
Not funded
2021 - 2021 Agentes de contraste à base de gadolínio na insuficiência renal: estudos de ADMET
PTDC/MED-OUT/1991/2021
Researcher
Fundação para a Ciência e a Tecnologia
Not funded
2021 - 2021 Winemaking By-Products for the Treatment of Kidney Disease
PTDC/MED-QUI/0263/2021
Researcher
Fundação para a Ciência e a Tecnologia
Not funded
2021 - 2021 Avaliação do impacto dos efeitos EPIgenéticos de CAnabinoides no neurodesenvolvimento
PTDC/SAU-TOX/1009/2021
Researcher
Fundação para a Ciência e a Tecnologia
Not funded
2021 - 2021 Uma estratégia biotecnológica sustentável para a prevenção da Deficiência de Iodo baseada em macroalgas e excedente de levedura de cerveja
EXPL/BAA-AGR/1595/2021
Researcher
Fundação para a Ciência e a Tecnologia
Not funded
2021 - 2021 Desenvolvimento de embalagem funcional e segura para alimentos à base de nanocompósitos de óxido de zinco e nanocelulose
PTDC/OCE- ETA/4846/2021
Researcher
Fundação para a Ciência e a Tecnologia
Not funded
2017/06 - 2020/05 CNPq/Universal 2016 - Evaluation of the mixture effects of agrochemicals used in soybean cultivation in RS
CNPq_93f3bfee10
Researcher
The Brazilian National Council for Scientific and Technological Development (CNPq)
2020 - 2020 Desenvolvimento de embalagem funcional e segura para alimentos à base de nanocompósitos de óxido de zinco e nanocelulose
PTDC/NAN-MAT/7410/2020
Researcher
Fundação para a Ciência e a Tecnologia
2020 - 2020 O Santo Graal das Ciências Forenses: estimar o intervalo postmortem através das alterações bioquímicas e do perfil de degradação do ARN no cadáver
PTDC/BIA-BQM/6669/2020
Researcher
Fundação para a Ciência e a Tecnologia
Not funded
2020 - 2020 Hybrid biomaterials systems based on halloysite clay nanotubes and medicinal plants for cutaneous infections
PTDC/NAN-MAT/5002/2020
Researcher
Fundação para a Ciência e a Tecnologia
Not funded
2019/01/01 - 2019/12/31 Unidade de Ciências Biomoleculares Aplicadas
UID/Multi/04378/2019
Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2016/04 - 2019/03 DESignBIOtecHealth – New Technologies for Three Health Challenges of Modern Societies: Diabetes, Drug Abuse and Kidney Diseases
NORTE-01-0145-FEDER-000024
Post-doc
The Norte Portugal Regional Coordination and Development Commission ( CCDR-N) / NORTE2020 / Portugal 2020
2019 - 2019 Untangling the molecular mechanisms underlying the hepatotoxicity of new psychoactive substances (NPS)
TOXhepNPS
Principal investigator
Fundação para a Ciência e a Tecnologia
Not funded
2019 - 2019 Tackling Nutritional Deficiencies in Childhood with Anti- Inflammatory Functional Foods Based on African Crops
Nutr-IN-Africa
Researcher
Fundação para a Ciência e a Tecnologia
Not funded
2018/01/01 - 2018/12/31 CorkPlus 3310 project – Contribution of cork stoppers to the chemical and sensory properties of bottled wine
CorkPlus 3310
Participação pontual
Fundação para a Ciência e a Tecnologia
Concluded
2018 - 2018 Latent fingerprint chemical profiling – identification of time-dependent metabolic markers
LFChemPro-CESPU-2018
Principal investigator
Instituto de Investigação e Formação Avançada em Ciências e Tecnologias da Saúde, Portugal
 Instituto de Investigação e Formação Avançada em Ciências e Tecnologias da Saúde
Ongoing
2016/01/01 - 2018 TOX-OER (Learning Toxicology through Open Educational Resources)
N/A
Technical development
Erasmus Plus
Ongoing
2017/01/01 - 2017 Interactions between environmental carcinogens: a genotoxic and metabolomics approach
2017C-A
Principal investigator
Rede de Química e Tecnologia Laboratório Associado para a Química Verde
Concluded
2017 - 2017 Drug-induced toxicity. The role of cholesterol accumulation in non-alcoholic steatohepatitis and other related morbidities
SAICT-45-2017-02/31471
Co-Principal Investigator (Co-PI)
Fundação para a Ciência e a Tecnologia
Not funded
2013/01 - 2015/06 Chelators for novel therapeutic strategies
Norte-07-0124-FEDER-000066
Post-doc
European Regional Development Fund
2013/01 - 2015/06 Nanochemistry
Norte-07-0124-FEDER-000067
Post-doc Fellow
European Regional Development Fund
2009 - 2012 Study of the toxicological interactions between amphetamine designer drugs in polydrug abuse context
SFRH/BD/45617/2008
PhD Student Fellow
Foundation for Science and Tecnology (FCT)

Other

Designation Funders
2021 - 2024 Toxicological study of Psilocybe-derived phytochemicals
Albert Labs
Co-Principal Investigator (Co-PI)
Albert Labs International
Ongoing
Outputs

Publications

Book chapter
  1. Dias da Silva, Diana; Miranda, D. "Aditivos alimentares e questões de segurança". In Toxicologia Alimentar, edited by Dinis-Oliveira, Ricardo Jorge; Carvalho, Félix. Lidl, 2023.
  2. Roque Bravo, Rita; Silva, João Pedro; Carmo, Helena; Carvalho, Félix; Dias da Silva, Diana. Corresponding author: Dias da Silva, Diana. "The Toll of Benzofurans in the Context of Drug Abuse". In Handbook of Substance Misuse and Addictions, 1-24. Springer International Publishing, 2022.
    10.1007/978-3-030-67928-6_168-1
  3. Brito-da-Costa, Andreia Machado; Dias da Silva, Diana; Madureira-Carvalho, Áurea; Dinis-Oliveira, Ricardo Jorge. Corresponding author: Dias da Silva, Diana. "Psilocybin and Magic Mushrooms: Patterns of Abuse and Consequences of Recreational Misuse". In Handbook of Substance Misuse and Addictions, 2427-2455. Springer International Publishing, 2022.
    10.1007/978-3-030-92392-1_130
Conference abstract
  1. Brito-da-Costa, AM; Silva-Carvalho, Mariana; Dinis-Oliveira, Ricardo Jorge; Madureira-Carvalho, Áurea; Dias da Silva, Diana. "Psilocin is an inhibitor of CYP450 enzymes CYP2A6 and CYP3A4". Paper presented in 54th Meeting of the Portuguese Society of Pharmacology, 42nd Meeting of Clinical Pharmacology, 23rd Meeting of Toxicology, Lisboa, 2024.
    Published
  2. Brito-da-Costa, AM; Carvalho, Mariana; Dinis-Oliveira, Ricardo Jorge; Madureira-Carvalho, Áurea; Sousa, Sérgio F.; Dias da Silva, Diana. "In vitro and in silico evaluation of psilocybin and psilocin’s interaction with CYP450 enzymes". Paper presented in III 1H-TOXRUN International Congress - Scientific Letters, Porto, 2024.
    Published • 10.48797/sl.2024.236
  3. Brito-da-Costa, AM; Carvalho, Mariana; Dinis-Oliveira, Ricardo Jorge; Madureira-Carvalho, Áurea; Sousa, Sérgio F.; Dias da Silva, Diana. "In vitro and in silico evaluation of 5-MeO-DMT, LSD, and mescaline’s interaction with CYP450 enzymes". Paper presented in III 1H-TOXRUN International Congress - Scientific Letters, Porto, 2024.
    Published • 10.48797/sl.2024.237
  4. Roque-Bravo, Rita; Carmo, Helena; Silva, João Pedro; Carvalho, Félix; Dias da Silva, Diana. "P21-11: Synthetic Cannabinoids and senescence markersi n vitro: impact on cell proliferation, influence of cannabinoid receptors, and beta-galactosidase activity in SH-SY5Y cells". Paper presented in 57th Congress of the European Societies of Toxicology (EUROTOX), Ljubljana, 2023.
    Published
  5. Brito-da-Costa, Andreia Machado; Silva-Carvalho, Mariana; Dinis-Oliveira, Ricardo Jorge; Madureira-Carvalho, Áurea; Dias da Silva, Diana. "Inhibitory activity of psilocybin/psilocin towards the enzymes of the cytochrome P450 (CYP450): An in vitro evaluation". Paper presented in II TOXRUN INTERNATIONAL CONGRESS 2023, Porto, 2023.
    Published
  6. Silva-Carvalho, Mariana; Brito-da-Costa, AM; Dinis-Oliveira, Ricardo Jorge; Madureira-Carvalho, Áurea; Dias da Silva, Diana. "Assessment of the CYP450 inhibitory potential of LSD, 5-MeO-DMT and mescaline: an in vitro study". Paper presented in Scientific Letters , II TOXRUN INTERNATIONAL CONGRESS 2023, Porto, 2023.
    Published
  7. Teixeira, MJ; Dias da Silva, Diana. "Clinical and toxicological effects of GLP-1 agonists". Paper presented in Scientific Letters, 2023.
  8. Dias da Silva, Diana; Roque-Bravo, R.; Silva, JP; Carmo, H; Carvalho, F. "The synthetic cannabinoids ADB-FUBINACA and AMB-FUBINACA accelerate SH-SY5Y proliferation via stimulation of CB1 and CB2 cannabinoid receptors". Paper presented in Scientific Letters, 2023.
  9. Brito-da-Costa, AM; Silva-Carvalho, Mariana; Dinis-Oliveira, Ricardo Jorge; Madureira-Carvalho, Áurea; Dias da Silva, Diana. "Assessment of the CYP450 inhibitory activity of psilocybin, psilocin, LSD, 5-MeO-DMT and mescaline: An in vitro study". Paper presented in 57th Congress of the European Societies of Toxicology (EUROTOX), Ljubljana, 2023.
  10. Roque Bravo, Rita; Barbosa, D.J.; Carmo, Helena; Silva, João Pedro; Carvalho, Félix; Dias da Silva, Diana. "The influence of selected synthetic cannabinoids on in vitro proliferation and viability of neuronal cell models". Paper presented in XVI International Congress of Toxicology, Maastricht, 2022.
    Published
  11. Monteiro, Vânia; Bramatti, Isabella; Amaro, Filipa; Guedes de Pinho, Paula; Figueiredo, Neusa; Dias da Silva, Diana; Martins, Marta; Pinto, Joana. "Impact of benzo[a]pyrene, phenanthrene, and their mixtures on the metabolome of hepatocytes isolated from fish". Paper presented in APCF-TOXRUN International Congress. RevSALUS - Revista Científica Internacional da Rede Académica Das Ciências Da Saúde da Lusofonia, 2022.
    Published • 10.51126/revsalus.v4iSup.246
  12. Brito-da-Costa, Andreia Machado; Dias da Silva, Diana; Madureira-Carvalho, Áurea; Dinis-Oliveira, Ricardo Jorge. Corresponding author: Brito-da-Costa, Andreia Machado. "Otimização de um método de cromatografia gasosa acoplada a espetrometria de massa (GC-MS) para a deteção e quantificação de psilocibina e psilocina". Paper presented in 4ª Reunião Internacional Rede Académica das Ciências da Saúde da Lusofonia, 2022.
    Published
  13. Brito-da-Costa, AM; Madureira-Carvalho, Áurea; Dinis-Oliveira, Ricardo Jorge; Dias da Silva, Diana. "Simultaneous detection and quantification of psilocybin and psilocin by gas chromatography coupled to mass spectrometry (GC-MS).". Paper presented in XVIth International Congress of Toxicology (ICT), Maastricht, 2022.
    Published • 10.1016/j.toxlet.2022.07.280
  14. Lemos Martins, Sofia; Brito-da-Costa, AM; Madureira-Carvalho, Áurea; Dinis-Oliveira, Ricardo Jorge; Dias da Silva, Diana. "Psilocybin and Psilocin as new tools to fight depression: an overview of the Pharmacodynamic and pharmacokinetic mechanisms". Paper presented in RevSALUS - Revista Científica Internacional Da Rede Académica Das Ciências Da Saúde Da Lusofonia, 2022.
    Published • 10.51126/revsalus.v4iSup.271
  15. Garcia, MR; Roque Bravo, R; Carmo, H; Carvalho, F; Silva, JP; Dias da Silva, Diana. "Mitochondrial effects and Caspase-3 activation induced by synthetic cannabinoids in NG108-15 cells". Paper presented in RevSALUS - Revista Científica Internacional Da Rede Académica Das Ciências Da Saúde Da Lusofonia, 2022.
  16. Pina Águas, A; Carvalho, F; Carmo, H; Valente, MJ; Dias da Silva, Diana. "The impact of cannabinoids in Schizophrenia: a systematic review". Paper presented in RevSALUS - Revista Científica Internacional Da Rede Académica Das Ciências Da Saúde Da Lusofonia, 2022.
  17. Lobato Freitas, C; Carmo, H; Carvalho, F; Silva, JP; Dias da Silva, Diana. "AMB-Fubinaca, AB-Chminaca and HU-308’s effects on in vitro differentiation and proliferation of NG108-15 cells". Paper presented in RevSALUS - Revista Científica Internacional Da Rede Académica Das Ciências Da Saúde Da Lusofonia, 2022.
  18. Cardoso, C; Dias da Silva, Diana; Duarte, V; Madureira-Carvalho, Áurea. "Characterisation of pet-related crimes in the judicial district of Setúbal since 2014: factors conditioning the applicability of the law 69/2014". Paper presented in RevSALUS - Revista Científica Internacional Da Rede Académica Das Ciências Da Saúde Da Lusofonia, 2022.
  19. Cardoso, C; Dias da Silva, Diana; Nery-Norte, C; Duarte, V; Madureira-Carvalho, Áurea. "An overview of the Historical, conceptual and legal framework of pet abuse". Paper presented in RevSALUS - Revista Científica Internacional Da Rede Académica Das Ciências Da Saúde Da Lusofonia, 2022.
  20. Pereira Teixeira, C; Garcia, MR; Roque Bravo, R; Carmo, H; Carvalho, F; Silva, JP; Dias da Silva, Diana. "Synthetic cannabinoids affect the expression of autophagic mediators ATG5, BECLIN-1, RAB7A and LC3 in brain-derived NG108-15 cells". Paper presented in RevSALUS - Revista Científica Internacional Da Rede Académica Das Ciências Da Saúde Da Lusofonia,, 2022.
  21. Paiva Ferreira, D; Russo, M; Dinis-Oliveira, RJ; Dias da Silva, Diana. "Acute poisoning in children: an old global problem". Paper presented in APCF-TOXRUN International Congress. RevSALUS - Revista Científica Internacional da Rede Académica Das Ciências Da Saúde da Lusofonia, 2022.
  22. Garcia, H; Roque Bravo, R; Dias da Silva, Diana. "Patterns of prevalence of drugs use in the university student population". Paper presented in APCF-TOXRUN International Congress. RevSALUS - Revista Científica Internacional da Rede Académica Das Ciências Da Saúde da Lusofonia, 2022.
  23. Martins, M; Fernandes, L; Lobo, F; Loureiro, J; Dias da Silva, Diana. "Characterisation of environmental law violations and wildlife seizures in Portugal, 2003-2019". Paper presented in APCF-TOXRUN International Congress. RevSALUS - Revista Científica Internacional da Rede Académica Das Ciências Da Saúde da Lusofonia, 2022.
  24. Martins, M; Fernandes, L; Lobo, F; Loureiro, J; Dias da Silva, Diana. "Patterns of illegal wildlife trade: the scale of the problem". Paper presented in APCF-TOXRUN International Congress. RevSALUS - Revista Científica Internacional da Rede Académica Das Ciências Da Saúde da Lusofonia, 2022.
  25. Russo, M; Dinis-Oliveira, RJ; Guimarães, R; Dias da Silva, Diana. "Acute poisoning in children and adolescents admitted to the pediatric emergency unit of the Hospital de São João (Porto, Portugal), 2014-2018". Paper presented in APCF-TOXRUN International Congress. RevSALUS - Revista Científica Internacional da Rede Académica Das Ciências Da Saúde da Lusofonia, 2022.
  26. Roque Bravo, R; Barbosa, D; Carmo, H; Carvalho, F; Silva , JP; Dias da Silva, Diana. "Synthetic cannabinoids AMB-FUBINACA, ADB-FUBINACA, AB-CHMINACA and THJ-2201 impact on in vitro viability and proliferation of primary rat hippocampal neurons and SH-SY5Y cells". Paper presented in APCF-TOXRUN International Congress. RevSALUS - Revista Científica Internacional da Rede Académica Das Ciências Da Saúde da Lusofonia, 2022.
  27. Madureira-Carvalho, Áurea; Brito-da-Costa, AM; Dias da Silva, Diana; Dinis-Oliveira, Ricardo Jorge. "Ayahuasca and N,N-dimethyltryptamine (DMT): Toxicokinetics, toxicodynamics, and biological effects". Paper presented in Toxicology Letters, 2022.
  28. Dias da Silva, Diana; Dinis-Oliveira, Ricardo Jorge; Lemos Martins, Sofia; Brito-da-Costa, AM; Madureira-Carvalho, Áurea. "Magic mushrooms and psilocybin: pharmacokinetics, pharmacodynamics, and clinical applications". Paper presented in Toxicology Letters, 2022.
  29. Silva, R; Barbosa, DJ; Carmo, H; Carvalho, F; Dias da Silva, Diana; Silva, JP. "The synthetic cannabinoid THJ-2201 increases the differentiation of primary hippocampal neurons and early astrocyte activation but decreases neuronal maturation". Paper presented in Toxicology Letters, 2022.
  30. Carmo, Helena; Rouxinol, Daniela; Silva, João Pedro; Bastos, Maria de Lourdes; Carvalho, Félix; Dias da Silva, Diana. "Release of Antidiuretic Hormone (ADH) in Wistar Rats in Response to the Administration of Methylone and 3,4-DMMC: The Gender Impact". Paper presented in 51st Meeting of the Portuguese Society of Pharmacology, 39th Meeting of Clinical Pharmacology and 20th Meeting of Toxicology, Lisboa, 2021.
    Published
  31. Malheiro, RF; Gomes, TM; Galani, M; Dias da Silva, Diana; Carmo, H; Carvalho, F; Silva, JP. "ADB-FUBINACA, a Synthetic Cannabinoid, Enhances In Vitro Neuronal Differentiation at Biologically Relevant Concentrations". Paper presented in The Toxicologist, Supplement to Toxicological Sciences,, 2021.
  32. Russo, M; Viana, J; Almeida Santos, L; Guimarães, R; Carvalho, F; Dinis-Oliveira, RJ; Dias da Silva, Diana. "Paediatric intoxications in the North of Portugal between 2014 and 2018". Paper presented in 15th YES Meeting – Abstracts. Porto Biomedical Journal, 2020.
  33. Roque-Bravo, R.; Carmo, H; Silva, JP; Carvalho, F; Bastos, ML; Dias da Silva, Diana. "The CYP2E1 metabolism increases in vitro hepatotoxicity of the synthetic psychostimulant 4-fluoromethamphetamine". Paper presented in 15th YES Meeting – Abstracts. Porto Biomedical Journal, 2020.
  34. Pinto, AC; Monteiro, V; Pinto, J; Guedes de Pinho, P; Diniz, MS; Martins, M; Dias da Silva, Diana. "Combination effects between environmental carcinogens in primary rat hepatocytes". Paper presented in 15th YES Meeting – Abstracts. Porto Biomedical Journal, 2020.
  35. Rouxinol, D; Dias da Silva, Diana; Silva, JP; Bastos, ML; Carvalho, F; Carmo, H. "Gas Chromatography–Mass Spectrometry (GC–MS) for analysis of biodistribution and metabolic profile of 3,4-dimethylmethcathinone (3,4- DMMC) in Wistar rats". Paper presented in 15th YES Meeting – Abstracts. Porto Biomedical Journal, 2020.
  36. Faria, AC; Carmo, Helena; Teixeira, Catarina; Rouxinol, D; Silva, João Pedro; Carvalho, Félix; Bastos, ML; Dias da Silva, Diana. "Administration of 3,4-dimethylmethcathinone (3,4-DMMC) and methylone increases the release of antidiuretic hormone in female Wistar rats. Published in Toxicology Letters". Paper presented in EUROTOX2019 ¿ 55th Congress of the European Societies of Toxicology, Helsinki, 2019.
    Accepted
  37. Teixeira, C; Carmo, Helena; Rouxinol, D; Faria, AC; Silva, João Pedro; Carvalho, Félix; Bastos, ML; Dias da Silva, Diana. "Administration of 3,4-dimethylmethcathinone (3,4-DMMC) and methylone to Wistar rats disturbs the energetic and antioxidant homeostasis in liver, brain, kidney and heart. Published in Toxicology Letters". Paper presented in EUROTOX2019 ¿ 55th Congress of the European Societies of Toxicology, Helsinki, 2019.
  38. Rouxinol, D; Dias da Silva, Diana; Teixeira, C; Faria, AC; Silva, João Pedro; Carvalho, Félix; Bastos, ML; Carmo, Helena. "Biodistribution of the new psychoactive stimulant 3,4-dimethylmethcathinone (3,4-DMMC) in Wistar rats assessed by gas chromatography-mass spectrometry (GC-MS). Published in Toxicology Letters". Paper presented in Eurotox2019, Helsinki, 2019.
  39. Roque Bravo, Rita; Carmo, Helena; Silva, João Pedro; Carvalho, Félix; Bastos, ML; Dias da Silva, Diana. "Metabolism plays an important role in the in vitro hepatotoxicity of butylone, buphedrone, and 3,4-dimethylmetcathinone (3,4-DMMC). Published in Toxicology Letters". Paper presented in EUROTOX2019, Helsinki, 2019.
    Accepted
  40. Alexandre, JA; Malheiro, RM; Dias da Silva, Diana; Carmo, Helena; Carvalho, Félix; Silva, João Pedro. "Synthetic cannabinoids 5F-PB22 and THJ-2201 promote in vitro CB1 receptor-dependent neuronal differentiation at in vivo-relevant concentrations. Published in Toxicology Letters (SENIOR AUTHOR)". Paper presented in EUROTOX2019, Helsinki, 2019.
    Accepted
  41. Teixeira, Catarina; Carmo, Helena; Rouxinol, Daniela; Faria, Ana Carolina; Silva, João Pedro; Carvalho, Félix; Dias da Silva, Diana. "Administration of 3,4-dimethylmethcathinone (3,4-DMMC) and methylone to Wistar rats disturbs the energetic and antioxidant homeostasis in liver, brain, kidney and heart". Paper presented in The 55th Congress of the European Societies of Toxicology (EUROTOX 2019), Helsinki, 2019.
    Published
  42. Rouxinol, Daniela; Dias da Silva, Diana; Teixeira, Catarina; Faria, Ana Carolina; Silva, João Pedro; Carvalho, Félix; Bastos, Maria de Lourdes; Carmo, Helena. "Biodistribution of the new psychoactive stimulant 3,4-dimethylmethcathinone (3,4-DMMC) in Wistar rats assessed by gas chromatography-mass spectrometry (GC-MS).". Paper presented in The 55th Congress of the European Societies of Toxicology (EUROTOX 2019), Helsinki, 2019.
    Published
  43. Roque Bravo, Rita; Carmo, Helena; Silva, João Pedro; Carvalho, Félix; Bastos, Maria de Lourdes; Dias da Silva, Diana. "Metabolism plays an important role in the in vitro hepatotoxicity of butylone, buphedrone, and 3,4-dimethylmetcathinone (3,4-DMMC)". Paper presented in The 55th Congress of the European Societies of Toxicology (EUROTOX 2019), Helsinki, 2019.
    Published
  44. Alexandre, João; Malheiro, Rui; Dias da Silva, Diana; Carmo, Helena; Carvalho, Félix; Silva, João Pedro. "Synthetic cannabinoids 5F-PB22 and THJ-2201 promote in vitro CB1 receptor-dependent neuronal differentiation at in vivo-relevant concentrations". Paper presented in The 55th Congress of the European Societies of Toxicology (EUROTOX 2019), Helsinki, 2019.
    Published
  45. R.R.D.S. Bravo; P. Moreira; F. Carvalho; M.D.L. Bastos; H. Carmo; D. Dias da Silva. "The synthetic psychostimulant 4-fluoromethamphetamine induces in vitro hepatotoxic effects, via CYP2E1 metabolism". Paper presented in The 54th Congress of the European Societies of Toxicology (EUROTOX 2018), Brussels, 2018.
    Published • 10.1016/j.toxlet.2018.06.866
  46. F. Carvalho; M.D.L. Bastos; S.O. Silva; H. Carmo; D.D.D. Silva. "Benzylpiperazine (BZP) additively increases Methylenedioxymethamphetamine (MDMA) cardiotoxicity in H9c2 cells, an effect potentiatted by hyperthermia". Paper presented in The 54th Congress of the European Societies of Toxicology (EUROTOX 2018), Brussels, 2018.
    Published • 10.1016/j.toxlet.2018.06.588
  47. P. Guedes de Pinho; D. Sousa; F. Carvalho; H. Carmo; M.D.L. Bastos; D. Dias da Silva. "2,4-Dinitrophenol (2,4-DNP) induces toxicity in primary hepatocytes through oxidative stress and mitochondrial dysregulation". Paper presented in The 54th Congress of the European Societies of Toxicology (EUROTOX 2018), Brussels, 2018.
    Published • 10.1016/j.toxlet.2018.06.870
  48. Maria João Martins; Patricia Moreira; Rita Roque Bravo; Helena Carmo; Félix Carvalho; Maria de Lourdes Bastos; Ricardo Jorge Dinis-Oliveira; Diana Dias da Silva. "Oxidative damage and energetic crisis in cardiomyocites after co-exposure of cocaine and morphine". Paper presented in EUROTOX 2017 – 53rd Congress of the European Societies of Toxicology, Bratislava, 2017.
    Published • 10.1016/j.toxlet.2017.07.451
  49. D. Dias Da Silva; A. Ferreira; M. Martins; M. Valente; F. Remião; F. Carvalho; M. Bastos; H. Carmo. "In vitro neurotoxicity of ‘Legal X’: The combination of 1-benzylpiperazine (BZP) and 1-(m-trifluoromethylphenyl)piperazine (TFMPP) induces mitochondrial impairment and disrupts thiol homeostasis in dopaminergic SH-SY5Y cells". Paper presented in 52nd European Congress of the European Societies of Toxicology, EUROTOX 2016, Seville, 2016.
    Published • 10.1016/j.toxlet.2016.06.1877
  50. M. Martins; A. Pinto; R.R. Bravo; H. Carmo; F. Carvalho; M. Bastos; R. Dinis-Oliveira; D. Dias da Silva. "Cocaine combined with heroin/morphine or ethanol disrupts mitochondrial and oxidative homeostasis". Paper presented in 52nd European Congress of the European Societies of Toxicology, EUROTOX 2016, Seville, 2016.
    Published • 10.1016/j.toxlet.2016.06.1849
  51. Dias da Silva, Diana; Moreira, Patricia; Silva, Maria João; Carmo, Helena. "In Vitro Hepatotoxicity of Mixtures of Benzylpiperazine (BZP) and 3-Tri uoromethylphenylpiperazine (TFMPP)". Paper presented in 55th Annual Meeting of the Society of Toxicology, New Orleans, 2016.
    Published
  52. Cammarano, I.D.; Carmo, H.; Silva, E.; da Silva, D. Dias. "Neurotoxic mixture effects of amphetamines, alcohol, tobacco and caffeine in SHSY-5Y dopaminergic cells – The effect of temperature". Paper presented in The 51st Congress of the European Societies of Toxicology, Porto, 2015.
    Published • 10.1016/j.toxlet.2015.08.1011
  53. da Silva, D. Dias; Ponte, F.; Moniz, T.; Carmo, H.; Carvalho, F.; Remião, F.; Rangel, M.C.; Bastos, M.L.. "Zinc (II) 3-hydroxy-4-pyridinones as potential agents for Diabetes mellitus: Evaluation of toxicity and efficacy in HepG2, Caco-2, and 3T3-L1 cells". Paper presented in The 51st Congress of the European Societies of Toxicology, Porto, 2015.
    Published • 10.1016/j.toxlet.2015.08.775
  54. M. Arbo; D. Dias da Silva; M.J. Valente; M.L. Bastos; H. Carmo. "Comparison of three different in vitro models for the evaluation of the hepatotoxicity of piperazine designer drugs". Paper presented in The 51st Congress of the European Societies of Toxicology, Porto, 2015.
    Published • 10.1016/j.toxlet.2015.08.732
  55. da Silva, D. Dias; Silva, M.J.; Araújo, A.M.; Valente, M.J.; Carmo, H.. "Mixtures of benzylpiperazine (BZP) and 3-trifluoromethylphenylpiperazine (TFMPP) elicit hepatotoxic effects in human HepaRG cells and primary rat hepatocytes". Paper presented in The 51st Congress of the European Societies of Toxicology, Porto, 2015.
    Published • 10.1016/j.toxlet.2015.08.1012
Conference poster
  1. Brito-da-Costa, AM; Carvalho, Mariana; Dinis-Oliveira, Ricardo Jorge; Madureira-Carvalho, Áurea; Sousa, Sérgio F.; Dias da Silva, Diana. "In vitro and in silico evaluation of psilocybin and psilocin’s interaction with CYP450 enzymes". Paper presented in III 1H-TOXRUN International Congress, 2024.
  2. Brito-da-Costa, AM; Carvalho, Mariana; Dinis-Oliveira, Ricardo Jorge; Madureira-Carvalho, Áurea; Sousa, Sérgio F.; Dias da Silva, Diana. "In vitro and in silico evaluation of 5-MeO-DMT, LSD, and mescaline’s interaction with CYP450 enzymes". Paper presented in III 1H-TOXRUN International Congress, 2024.
  3. Roque Bravo, Rita; Carmo, Helena; Silva, João Pedro; Carvalho, Félix; Dias da Silva, Diana. "Synthetic Cannabinoids and senescence markersi n vitro: impact on cell proliferation, influence of cannabinoid receptors, and beta-galactosidase activity in SH-SY5Y cells". Paper presented in 57th Congress of the European Societies of Toxicology (EUROTOX), 2023.
  4. Brito-da-Costa, AM; Silva-Carvalho, Mariana; Dinis-Oliveira, Ricardo Jorge; Madureira-Carvalho, Áurea; Dias da Silva, Diana. "Assessment of the CYP450 inhibitory activity of psilocybin, psilocin, LSD, 5-MeO-DMT and mescaline: An in vitro study". Paper presented in 57th Congress of The European Societies of Toxicology, 2023.
  5. Dias da Silva, Diana; Roque-Bravo, R.; Silva, JP; Carmo, H; Carvalho, F. "The synthetic cannabinoids ADB-FUBINACA and AMB-FUBINACA accelerate SH-SY5Y proliferation via stimulation of CB1 and CB2 cannabinoid receptors". Paper presented in International Congress of TOXRUN, 2023.
  6. Silva-Carvalho, M; Brito-da-Costa, AM; Dinis-Oliveira, Ricardo Jorge; Madureira-Carvalho, Áurea; Dias da Silva, Diana. "Assessment of the CYP450 inhibitory potential of LSD, 5-MeO-DMT and mescaline: An in vitro study". Paper presented in International Congress of TOXRUN, 2023.
  7. Teixeira, MJ; Dias da Silva, Diana. "CLINICAL AND TOXICOLOGICAL EFFECTS OF GLP-1 AGONISTS". Paper presented in International Congress of TOXRUN, 2023.
  8. Monteiro, Vânia; Bramatti, Isabella; Amaro, Filipa; Guedes de Pinho, Paula; Figueiredo, Neusa; Dias da Silva, Diana; Martins, Marta; Pinto, Joana. "Metabolic alterations induced by polycyclic aromatic hydrocarbons on the endometabolome of fish primary hepatocytes". Paper presented in Metabolomics 2022, 2022.
  9. Brito-da-Costa, AM; Dinis-Oliveira, Ricardo Jorge; Madureira-Carvalho, Áurea; Dias da Silva, Diana. "Optimisation of a gas chromatography coupled to a mass spectrometry (GC-MS) methodology for the simultaneous detection and quantification of psilocybin and psilocin". Paper presented in Ciência 2022 - Encontro com a Ciência e Tecnologia em Portugal, 2022.
  10. Roque Bravo, Rita; Barbosa, Daniel José; Carmo, Helena; Silva, João Pedro; Carvalho, Félix; Dias da Silva, Diana. "SYNTHETIC CANNABINOIDS AMB-FUBINACA, ADB-FUBINACA, AB-CHMINACA AND THJ-2201 IMPACT ON IN VITRO VIABILITY AND PROLIFERATION OF PRIMARY RAT HIPPOCAMPAL NEURONS AND SH-SY5Y CELLS". Paper presented in I Congresso Internacional da TOXRUN; V Congresso Internacional da Associação Portuguesa de Ciências Forenses, 2022.
  11. Dias da Silva, Diana; Pereira Teixeira, C; Garcia, MR; Roque-Bravo, R.; Carmo, H; Carvalho, F; Silva, JP. "Crosstalk between autophagic intermediaries in the event of neurotoxic effects mediated by Synthetic Cannabinoids in NG108-15 cells". Paper presented in Lisbon Addictions, 2022.
  12. Lobato-Freitas, C; Carmo, H; Carvalho, F; Silva, JP; Dias da Silva, Diana. "The effects of Synthetic Cannabinoids ADB-FUBINACA, AMB-FUBINACA, AB-CHMINACA and HU-308 on Differentiation and Proliferation of Brain NG108-15 Cells". Paper presented in Lisbon Addictions, 2022.
  13. Pina Águas, A; Carvalho, F; Carmo, H; Valente, MJ; Dias da Silva, Diana. "CANNABINOIDS AND SCHIZOPHRENIA: IS THERE A LINK?". Paper presented in Lisbon Addictions, 2022.
  14. Brito-da-Costa, AM; Dias da Silva, Diana; Madureira-Carvalho, Áurea; Dinis-Oliveira, Ricardo Jorge. "Patterns and consequences of recreational misuse of psilocybin and magic mushrooms". Paper presented in Lisbon Addictions, 2022.
  15. Silva, R; Barbosa, DJ; Carmo, H; Carvalho, F; Dias da Silva, Diana; Silva, JP. "The synthetic cannabinoid THJ-2201 increases the differentiation of primary hippocampal neurons and early astrocyte activation but decreases neuronal maturation". Paper presented in 16th (XVI) International Congress of Toxicology (ICT), 2022.
  16. Dias da Silva, Diana; Dinis-Oliveira, Ricardo Jorge; Lemos Martins, S; Brito-da-Costa, AM; Madureira-Carvalho, Áurea. "Magic mushrooms and psilocybin: pharmacokinetics, pharmacodynamics, and clinical applications". Paper presented in 16th (XVI) International Congress of Toxicology (ICT), 2022.
  17. Madureira-Carvalho, Áurea; Brito-da-Costa, AM; Dias da Silva, Diana; Dinis-Oliveira, Ricardo Jorge. "Ayahuasca and N,N-dimethyltryptamine (DMT): Toxicokinetics, toxicodynamics, and biological effects". Paper presented in 16th (XVI) International Congress of Toxicology (ICT), 2022.
  18. Brito-da-Costa, AM; Madureira-Carvalho, Áurea; Dinis-Oliveira, Ricardo Jorge; Dias da Silva, Diana. "Simultaneous detection and quantification of psilocybin and psilocin by gas chromatography coupled to mass spectrometry (GC- MS)". Paper presented in 16th (XVI) International Congress of Toxicology (ICT), 2022.
  19. Lemos Martins, S; Brito-da-Costa, AM; Madureira-Carvalho, Áurea; Dinis-Oliveira, Ricardo Jorge; Dias da Silva, Diana. "Psilocybin and psilocin as new tools to fight depression: as overview of the pharmacodynamic and pharmacokinetic mechanisms". Paper presented in Annual Congress of APCF-TOXRUN, 2022.
  20. Russo, M; Dinis-Oliveira, Ricardo Jorge; Guimarães, R; Dias da Silva, Diana. "Acute poisoning in children and adolescents admitted to the paediatric emergency unit of the hospital de São João (Porto, Portugal), 2014-2018". Paper presented in Annual Congress of APCF-TOXRUN, 2022.
  21. Martins, M; Fernandes, L; Lobo, F; Loureiro, J; Dias da Silva, Diana. "Patterns of illegal wildlife trade: the scale of the problem". Paper presented in Annual Congress of APCF-TOXRUN, 2022.
  22. Martins, M; Fernandes, L; Lobo, F; Loureiro, J; Dias da Silva, Diana. "Characterization of environmental law violations and wildlife seizures in Portugal, 2003-2019". Paper presented in Annual Congress of APCF-TOXRUN, 2022.
  23. Garcia, H; Roque-Bravo, R.; Dias da Silva, Diana. "Patterns of prevalence of drug use in the university student population". Paper presented in Annual Congress of APCF-TOXRUN, 2022.
  24. Paiva Ferreira, D; Russo, M; Dinis-Oliveira, Ricardo Jorge; Dias da Silva, Diana. "Acute poisoning in children: an old global problem". Paper presented in Annual Congress of APCF-TOXRUN, 2022.
  25. Pereira Teixeira, C; Garcia, MR; Roque Bravo, Rita; Carmo, H; Carvalho, F; Silva, JP; Dias da Silva, Diana. "Synthetic cannabinoids affect expression of autophagic mediators ATG5, beclin-a, Rab7a and LC3 in NG108-15 brain-derived cells". Paper presented in Annual Congress of APCF-TOXRUN, 2022.
  26. Cardoso, C; Dias da Silva, Diana; Nery-Norte, C; Duarte, V; Madureira-Carvalho, Áurea. "An overview of the historical, conceptual and legal framework of pet abuse". Paper presented in Annual Congress of APCF-TOXRUN, 2022.
  27. Cardoso, C; Dias da Silva, Diana; Duarte, V; Madureira-Carvalho, Áurea. "Characterization of pet-related crimes in the judicial district of Setubal since 2014: factors conditioning the applicability of the law nº 69/2014". Paper presented in Annual Congress of APCF-TOXRUN, 2022.
  28. Lobato Freitas, C; Carmo, H; Carvalho, F; Silva, JP; Dias da Silva, Diana. "AMB-FUBINACA, AB-CHMINACA and HU-308’s effects in in vitro differentiation and proliferation of NG108-15 cells". Paper presented in Annual Congress of APCF-TOXRUN, 2022.
  29. Pina Águas, A; Carvalho, F; Carmo, H; Valente, MJ; Dias da Silva, Diana. "The impact of cannabinoids in schizophrenia: A systematic review". Paper presented in Annual Congress of APCF-TOXRUN, 2022.
  30. Monteiro, Vânia; Pinto, Ana Cristina; Pinto, Joana; Guedes de Pinho, Paula; S. Diniz, Mário; Martins, Marta; Dias da Silva, Diana. "In vitro interactions between polycyclic aromatic hydrocarbons". Paper presented in IJUP21 14º Encontro de Investigação Jovem da Universidade do Porto, Porto, 2021.
  31. Malheiro, Rui F.; Gomes, Telma M; Galani, M; Dias da Silva, Diana; Carmo, Helena; Carvalho, Félix; Silva, Joao Pedro. Corresponding author: Silva, Joao Pedro. "ADB-FUBINACA, a synthetic cannabinoid, enhances in vitro neuronal differentiation at biologically relevant concentrations". Paper presented in Society of Toxicology (SOT) Virtual Annual Meeting, 2021.
  32. Pinto, Ana Cristina; Monteiro, Vânia; Guedes de Pinho, Paula; Diniz, Mário; Martins, Marta; Dias da Silva, Diana. "Combination effects between environmental carcinogens in primary rat hepatocytes". Paper presented in 15th Young European Scientist Meeting. Porto Biomedical Journal, 2020.
    10.1097/j.pbj.0000000000000100
  33. Rouxinol, Daniela; Dias da Silva, Diana; Silva, João Pedro; Bastos, Maria de Lourdes; Carvalho, Félix; Carmo, Helena. "Gas Chromatography–Mass Spectrometry (GC–MS) for analysis of biodistribution and metabolic profile of 3,4-dimethylmethcathinone (3,4- DMMC) in Wistar rats". Paper presented in 15th YES (Young European Scientist) Meeting – Digital Experience, 2020.
  34. Dias da Silva, Diana; Silva, João Pedro; Carmo, Helena; Bastos, Maria de Lourdes; Carvalho, Félix. "Pharmacokinetics and pharmacodynamics of the synthetic cannabinoid UR-144 and its halogenated analogue 5F-UR-144 (XLR-11)". Paper presented in 3ª Conferência Europeia sobre Comportamentos e Dependências Aditivas subordinada ao tema “The future of addictions — new frontiers for policy, practice and science, 2019.
  35. Roque Bravo, Rita; Duarte de Almeida, Tomás; Valente, Maria João; Ferreira, Bárbara; Rebelo, Rita; Silva, João Pedro; Carvalho, Félix; et al. "The in vitro hepatotoxicity of the new recreational drug 3-methylmethcathinone (3-MMC) involves autophagy and apoptosis". Paper presented in 3ª Conferência Europeia sobre Comportamentos e Dependências Aditivas subordinada ao tema “The future of addictions — new frontiers for policy, practice and science”, 2019.
  36. Rouxinol, Daniela; Dias da Silva, Diana; Silva, João Pedro; Carvalho, Félix; Bastos, Maria de Lourdes; Carmo, Helena. "Review: the newly emerged designer psychostimulant 3,4-dimethylmethcathinone (3,4-DMMC)". Paper presented in 3ª Conferência Europeia sobre Comportamentos e Dependências Aditivas subordinada ao tema “The future of addictions — new frontiers for policy, practice and science”, 2019.
  37. Faria, Ana Carolina; Carmo, Helena; Silva, João Pedro; Carvalho, Félix; Bastos, Maria de Lourdes; Dias da Silva, Diana. "Hyponatraemia induced by synthetic phenethylamines". Paper presented in 3ª Conferência Europeia sobre Comportamentos e Dependências Aditivas subordinada ao tema “The future of addictions — new frontiers for policy, practice and science”, 2019.
  38. Dias da Silva, Diana; Carmo, Helena; Carvalho, Félix; Silva, João Pedro. "Pharmacokinetics and pharmacodynamics of the synthetic cannabinoid UR-144 and its halogenated analogue 5F-UR-144 (XLR-11). (SENIOR AUTHOR)". Paper presented in Lisbon Addictions 2019, 2019.
  39. Rouxinol, D; Dias da Silva, Diana; Silva, João Pedro; Carvalho, Félix; Bastos, ML; Carmo, Helena. "The newly emerged designer psychostimulant 3,4-dimethylmethcathinone (3,4-DMMC)". Paper presented in Lisbon Addictions 2019, 2019.
  40. Alexandre, JA; Malheiro, RM; Dias da Silva, Diana; Carmo, Helena; Carvalho, Félix; Silva, João Pedro. "Synthetic cannabinoids 5F-PB22 and THJ-2201 promote in vitro CB1 receptor-dependent neuronal differentiation at in vivo-relevant concentrations. (SENIOR AUTHOR)". Paper presented in EUROTOX2019, 2019.
  41. Faria, Ana Carolina; Carmo, Helena; Teixeira, Catarina; Rouxinol, Daniela; Silva, João Pedro; Carvalho, Félix; Bastos, Maria de Lourdes; Dias da Silva, Diana. "Administration of 3,4-dimethylmethcathinone (3,4-DMMC) and methylone increases the release of antidiuretic hormone (ADH) in Wistar rats.". Paper presented in The 55th Congress of European Societies of Toxicology (EUROTOX, 2019.
  42. Matos, Jéssica; Santos, Ana; Dias da Silva, Diana; Dinis-Oliveira, Ricardo Jorge; Madureira-Carvalho, Áurea. "Development and optimization of protocols for the extraction of fingermark metabolites". Paper presented in IV Congresso da Associação Portuguesa de Ciências Forenses/ XIII Jornadas Científicas de Ciências do Instituto Universitário de Ciências da Saúde, 2019.
  43. Matos, Jéssica; Santos, Ana; Dias da Silva, Diana; Dinis-Oliveira, Ricardo Jorge; Madureira-Carvalho, Áurea. "Development and optimization of protocols for the extraction of fingerprints metabolites". Paper presented in IV Congress of the Portuguese Association of Forensic Sciences, 2019.
  44. Santos, Ana; Pinto, Diana; Dias da Silva, Diana; Andrade, Paula Branquinho; Dinis-Oliveira, Ricardo Jorge; Silva, Artur; Pinto Vieira, Paulo; Nelson G. M. Gomes; Madureira-Carvalho, Áurea. "IDENTIFICATION OF POTENTIAL TIME-DEPENDENT METABOLIC MARKERS FOR DATING FINGERMARKS". Paper presented in IV Congresso da Associação Portuguesa de Ciências Forenses e XI Jornadas Científicas do Departamento de Ciências do Instituto Universitário de Ciências da Saúde, 2019.
  45. Faria, Ana Carolina; Carmo, Helena; Teixeira, Catarina; Rouxinol, Daniela; Carvalho, Félix; Bastos, Maria de Lourdes; Dias da Silva, Diana. "INCREASED RELEASE OF ANTIDIURETIC HORMONE (ADH) FOLLOWING ADMINISTRATION OF CATHINONE ANALOGUES IN FEMALE WISTAR RATS". Paper presented in RATS IV Congresso da Associação Portuguesa de Ciências Forenses e XI Jornadas Científicas do Departamento de Ciências do Instituto Universitário de Ciências da Saúde, 2019.
  46. Cardoso, Catarina; Dias da Silva, Diana; Dinis-Oliveira, Ricardo Jorge; Ribeiro, Cláudia; Madureira-Carvalho, Áurea. "RECOVERY OF FINGERMARKS FROM ARSON SCENES". Paper presented in IV Congresso da Associação Portuguesa de Ciências Forenses e XI Jornadas Científicas do Departamento de Ciências do Instituto Universitário de Ciências da Saúde, 2019.
  47. Teixeira, Catarina; Carmo, Helena; Rouxinol, Daniela; Faria, Ana Carolina; Carvalho, Félix; Bastos, Maria de Lourdes; Dias da Silva, Diana. "3,4-DIMETHYLMETHCATHINONE (3,4-DMMC) AND METHYLONE AFFECT ENERGY LEVELS AND OXIDATIVE PARAMETERS IN DIFFERENT ORGANS OF WISTAR RATS". Paper presented in IV Congresso da Associação Portuguesa de Ciências Forenses e XI Jornadas Científicas do Departamento de Ciências do Instituto Universitário de Ciências da Saúde, 2019.
  48. Rouxinol, Daniela; Dias da Silva, Diana; Teixeira, Catarina; Faria, Ana Carolina; Carvalho, Félix; Bastos, Maria de Lourdes; Carmo, Helena. "GAS CHROMATOGRAPHY-MASS SPECTROMETRY (GC-MS) METHOD FOR THE ASSESSMENT OF THE BIODISTRIBUTION PROFILE OF THE NEW PSYCHOSTIMULANT 3,4-DIMETHYLMETHCATHINONE (3,4-DMMC) IN WISTAR RATS". Paper presented in IV Congresso da Associação Portuguesa de Ciências Forenses e XI Jornadas Científicas do Departamento de Ciências do Instituto Universitário de Ciências da Saúde, 2019.
  49. Dias da Silva, Diana; Roque Bravo, Rita; Duarte de Almeida, Tomás; Valente, Maria João; Ferreira, Bárbara; Rebelo, Rita; Carvalho, Félix; Bastos, Maria de Lourdes; Carmo, Helena. "ASSESSMENT OF THE POTENTIAL HEPATOTOXICITY OF THE PSYCHOSTIMULANT 3-METHYLMETHCATHINONE (3-MMC), USING PRIMARY RAT HEPATOCYTES". Paper presented in IV Congresso da Associação Portuguesa de Ciências Forenses e XI Jornadas Científicas do Departamento de Ciências do Instituto Universitário de Ciências da Saúde, 2019.
  50. Langa, Ivan Marcelino; Tiritan, Maria Elizabeth; Dias da Silva, Diana; Ribeiro, Cláudia. "MONITORING OF CHIRA DRUGS USED FOR RECREATIONAL PURPOSES IN SURFACE WATERS". Paper presented in IV Congresso da Associação Portuguesa de Ciências Forenses e XI Jornadas Científicas do Departamento de Ciências do Instituto Universitário de Ciências da Saúde, 2019.
  51. Matos, Jéssica; Santos, Ana; Dias da Silva, Diana; Dinis-Oliveira, Ricardo Jorge; Madureira-Carvalho, Áurea. "DEVELOPMENT AND OPTIMIZATION OF PROTOCOLS FOR THE EXTRACTION OF FINGERMARK METABOLITES". Paper presented in IV Congresso da Associação Portuguesa de Ciências Forenses e XI Jornadas Científicas do Departamento de Ciências do Instituto Universitário de Ciências da Saúde, 2019.
  52. Russo, Marta; Dinis-Oliveira, Ricardo Jorge; Guimarães Rui; Dias da Silva, Diana. "POISONING IN CHILDREN: SCALE OF THE PROBLEM". Paper presented in IV Congresso da Associação Portuguesa de Ciências Forenses e XI Jornadas Científicas do Departamento de Ciências do Instituto Universitário de Ciências da Saúde, 2019.
  53. Roque Bravo, Rita; Carmo, Helena; Carvalho, Félix; Bastos, Maria de Lourdes; Dias da Silva, Diana. "TOXICITY OF BUTYLONE, BUPHEDRONE AND 3,4-DIMETHYLMETHCATHINONE (3,4-DMMC) IN IN VITRO HEPATOCYTE MODELS". Paper presented in IV Congresso da Associação Portuguesa de Ciências Forenses e XI Jornadas Científicas do Departamento de Ciências do Instituto Universitário de Ciências da Saúde, 2019.
  54. Santos, Ana; Pinto, Diana C G A; Dias da Silva, Diana; Andrade, Paula Branquinho; Dinis-Oliveira, Ricardo Jorge; Silva, Artur M S; Pinto, Paulo; Nelson G. M. Gomes; Madureira-Carvalho, Áurea. "Endogenous components from fingermark residues: A chemical approach towards fingermark dating". Paper presented in IJUP – 12.º Encontro de Jovens Investigadores da U.PORTO, 2019.
  55. Duarte de Almeida, Tomás; Valente, Maria João; Dias da Silva, Diana; Carmo, Helena. "The involvement of autophagy in cellular death elicited by New Psychoactive Substances". Paper presented in 5º Congresso Anual do MEEting. Do MIM, 2019.
  56. Rouxinol, D; Dias da Silva, Diana; Teixeira, C; Faria, AC; Silva, JP; Carvalho, F; Bastos, ML; Carmo, H. "Biodistribution of the new psychoactive stimulant 3,4-dimethylmethcathinone (3,4-DMMC) in Wistar rats assessed by gas chromatography-mass spectrometry (GC-MS)". Paper presented in LV Congresso da Sociedade Europeia de Toxicologia (EUROTOX), 2019.
  57. Teixeira, C; Carmo, H; Rouxinol, D; Faria, AC; Silva, JP; Carvalho, F; Bastos, ML; Dias da Silva, Diana. "Administration of 3,4-dimethylmethcathinone (3,4-DMMC) and methylone to Wistar rats disturbs the energetic and antioxidant homeostasis in liver, brain, kidney and heart". Paper presented in LV Congresso da Sociedade Europeia de Toxicologia (EUROTOX), 2019.
  58. Faria, Ana Carolina; Carmo, Helena; Carvalho, Félix; Bastos, Maria de Lourdes; Dias da Silva, Diana. "DRUG-INDUCED HYPONATRAEMIA: THE CASE OF SYNTHETIC CATHINONES". Paper presented in 17.o Congresso Nacional de Medicina Legal e Ciências Forenses e 2ª Reunião da Rede de Serviços Médico-Legais de Língua Portuguesa, 2018.
  59. Enea, Maria; Dias da Silva, Diana; Pereira, Eulália; Soares, Maria Elisa; Bastos, Maria de Lourdes; Carmo, Helena. "Gold nanoparticles’ effect on an in vitro model of the brain blood barrier. Cytotoxicity, internalization and permeability studies". Paper presented in . LIV Congresso da Sociedade Europeia de Toxicologia (EUROTOX), 2018.
  60. Matos, Jéssica; Santos, Ana; Dinis-Oliveira, Ricardo Jorge; Dias da Silva, Diana; Madureira-Carvalho, Áurea; Nelson G. M. Gomes. "Mass Spectrometry: Versatility and Applications in Fingermarks Analysis". Paper presented in III Congress of the Portuguese Association of Forensic Sciences, 2018.
  61. Sousa, Daniela; Enea, Maria; Carmo, Helena; Carvalho, Félix; Bastos, Maria de Lourdes; Guedes de Pinho, Paula; Dias da Silva, Diana. "TOXICITY OF THE FAT BURNER 2,4-DINITROPHENOL (2,4-DNP) IN PRIMARY RAT HEPATOCYTES". Paper presented in XII Jornadas Científicas de Ciências do Instituto Universitário de Ciências da Saúde (IUCS-CESPU) e III Encontro Anual da Associação Portuguesa de Ciências Forenses (APCF), 2018.
  62. Ferreira, Bárbara; Dias da Silva, Diana; Carvalho, Félix; Bastos, Maria de Lourdes; Carmo, Helena. "A REVIEW ON THE NOVEL PSYCOACTIVE SUBSTANCE 3-METHYLMETHCATHINONE (3-MMC)". Paper presented in XII Jornadas Científicas de Ciências do Instituto Universitário de Ciências da Saúde (IUCS-CESPU) e III Encontro Anual da Associação Portuguesa de Ciências Forenses (APCF), 2018.
  63. Lança Pereira, Carolina; Dias da Silva, Diana; Dinis-Oliveira, Ricardo Jorge. "MESCALINE METABOLISM IN HUMANS". Paper presented in XII Jornadas Científicas de Ciências do Instituto Universitário de Ciências da Saúde (IUCS-CESPU) e III Encontro Anual da Associação Portuguesa de Ciências Forenses (APCF), 2018.
  64. Torcato Carrilho, Carolina; Dinis-Oliveira, Ricardo Jorge; Silva, Renata; Dias da Silva, Diana. "THE NEW PSYCHOACTIVE CANNABINOID XLR-11: PHARMACOKINETICS AND PHARMACODYNAMICS ASPECTS". Paper presented in XII Jornadas Científicas de Ciências do Instituto Universitário de Ciências da Saúde (IUCS-CESPU) e III Encontro Anual da Associação Portuguesa de Ciências Forenses (APCF), 2018.
  65. Faria, Ana Carolina; Carmo, Helena; Carvalho, Félix; Bastos, Maria de Lourdes; Dias da Silva, Diana. "HYPONATRAEMIA INDUCED BY SYNTHETIC CATHINONES". Paper presented in XII Jornadas Científicas de Ciências do Instituto Universitário de Ciências da Saúde (IUCS-CESPU) e III Encontro Anual da Associação Portuguesa de Ciências Forenses (APCF), 2018.
  66. Rouxinol, Daniela; Dias da Silva, Diana; Carvalho, Félix; Bastos, Maria de Lourdes; Carmo, Helena. "INTRACELLULAR MECHANISMS UNDERLYING THE TOXICITY OF SYNTHETIC CATHINONES". Paper presented in XII Jornadas Científicas de Ciências do Instituto Universitário de Ciências da Saúde (IUCS-CESPU) e III Encontro Anual da Associação Portuguesa de Ciências Forenses (APCF), 2018.
  67. Silva, Sara; Enea, Maria; Carvalho, Félix; Bastos, Maria de Lourdes; Carmo, Helena; Dias da Silva, Diana. "HYPERTHERMIA EXACERBATES THE CARDIOTOXICITY OF BENZYLPIPERAZINE (BZP) AND METHYLENEDIOXYMETHAMPHETAMINE (MDMA) COMBINATIONS IN H9C2 CELLS". Paper presented in XII Jornadas Científicas de Ciências do Instituto Universitário de Ciências da Saúde (IUCS-CESPU) e III Encontro Anual da Associação Portuguesa de Ciências Forenses (APCF), 2018.
  68. Roque Bravo, Rita; Moreira, Patrícia; Enea, Maria; Carmo, Helena; Carvalho, Félix; Bastos, Maria de Lourdes; Dias da Silva, Diana. "4-FLUOROMETHAMPHETAMINE EXERTS TOXICITY TO HEPATOCELLULAR IN VITRO MODELS VIA CYP450- MEDIATED METABOLISM". Paper presented in XII Jornadas Científicas de Ciências do Instituto Universitário de Ciências da Saúde (IUCS-CESPU) e III Encontro Anual da Associação Portuguesa de Ciências Forenses (APCF), 2018.
  69. Martins, Maria João; Roque Bravo, Rita; Enea, Maria; Carmo, Helena; Carvalho, Félix; Bastos, Maria de Lourdes; Dinis-Oliveira, Ricardo Jorge; Dias da Silva, Diana. "COCAINE AND ETHANOL ADDITIVELY IMPAIR OXIDATIVE, ENERGETIC AND MITOCHONDRIAL HOMEOSTASIS IN H9C2 CARDIOMYOCYTES". Paper presented in XII Jornadas Científicas de Ciências do Instituto Universitário de Ciências da Saúde (IUCS-CESPU) e III Encontro Anual da Associação Portuguesa de Ciências Forenses (APCF), 2018.
  70. Santos, Ana; Matos, Jéssica; Dinis-Oliveira, Ricardo Jorge; Dias da Silva, Diana; Vieira Pinto, Paulo; Gomes, Nelson; Madureira-Carvalho, Áurea. "ENDOGENOUS AND EXOGENOUS CONSTITUENTS OF FINGERPRINTS - DISCRIMINATORY POTENTIAL IN FORENSIC ANALYSIS". Paper presented in XII Jornadas Científicas de Ciências do Instituto Universitário de Ciências da Saúde (IUCS-CESPU) e III Encontro Anual da Associação Portuguesa de Ciências Forenses (APCF), 2018.
  71. Matos, Jéssica; Santos, Ana; Dinis-Oliveira, Ricardo Jorge; Dias da Silva, Diana; Gomes, Nelson; Madureira-Carvalho, Áurea. "MASS SPECTROMETRY: VERSATILITY AND APPLICATONS IN FINGERMARKS ANALYSIS". Paper presented in XII Jornadas Científicas de Ciências do Instituto Universitário de Ciências da Saúde (IUCS-CESPU) e III Encontro Anual da Associação Portuguesa de Ciências Forenses (APCF), 2018.
  72. Faria, Ana Carolina; Carmo, Helena; Carvalho, Félix; Bastos, Maria de Lourdes; Dias da Silva, Diana. "Hyponatraemia: a potential life threatening consequence of cathinones abuse.". Paper presented in III Congress of the Portuguese Association of Forensic Sciences, 2018.
  73. Martins, MJ; Roque-Bravo, R.; Carmo, H; Carvalho, F; Bastos, ML; Dinis-Oliveira, Ricardo Jorge; Dias da Silva, Diana. "Co-exposure to cocaine and ethanol induces oxidative impairment in H9c2 cardiomyocytes". Paper presented in LIV Congresso da Sociedade Europeia de Toxicologia (EUROTOX), 2018.
  74. Guedes de Pinho, P; Sousa, D; Carvalho, F; Carmo, H; Bastos, ML; Dias da Silva, Diana. "2,4-Dinitrophenol (2,4-DNP) induces toxicity in primary hepatocytes through oxidative stress and mitochondrial dysregulation". Paper presented in LIV Congresso da Sociedade Europeia de Toxicologia (EUROTOX), 2018.
  75. Roque-Bravo, R.; Moreira, P; Carvalho, F; Bastos, ML; Carmo, H; Dias da Silva, Diana. "The synthetic psychostimulant 4-fluoromethamphetamine induces in vitro hepatotoxic effects, via CYP2E1 metabolism". Paper presented in LIV Congresso da Sociedade Europeia de Toxicologia (EUROTOX), 2018.
  76. Carvalho, F; Bastos, ML; Silva, SO; Carmo, H; Dias da Silva, Diana. "Benzylpiperazine (BZP) additively increases Methylenedioxymethamphetamine (MDMA) cardiotoxicity in H9c2 cells, an effect potentiated by hyperthermia". Paper presented in LIV Congresso da Sociedade Europeia de Toxicologia (EUROTOX), 2018.
  77. Oliveira, AS; Pinto, P; Lopes, P; Cabral, M; Bastos, ML; Dias da Silva, Diana; Guedes de Pinho, P. "Anticancer potential of semi-volatile compounds present in cork: Cytotoxic mixture effects in human colorectal adenocarcinoma cells". Paper presented in LIV Congresso da Sociedade Europeia de Toxicologia (EUROTOX), 2018.
  78. Martins, Maria João; Moreira, Patricia; Roque Bravo, Rita; Carmo, Helena; Carvalho, Félix; Bastos, Maria de Lourdes; Dinis-Oliveira, Ricardo Jorge; Dias da Silva, Diana. "Oxidative damage and energetic crisis in cardiomyocytes after co-exposure of cocaine and morphine". Paper presented in LIII Congress of the European Toxicology Society (EUROTOX), 2017.
  79. Ferreira, Bárbara; Dias da Silva, Diana; Rebelo, Rita; Moreira, Patrícia; Carvalho, Félix; Bastos, Maria de Lourdes; Carmo, Helena. "Cytotoxicity of 3-methylmethcathinone (3-MMC or metaphedrone) in primary rat hepatocytes". Paper presented in V Encontro Anual da Sociedade Portuguesa para o Estudo da Criança Abusada e Negligenciada (SPECAN), II Encontro Anual da Associação Portuguesa de Ciências Forenses (APCF) e Jornadas Científicas de Ciências do Instituto Universitário de Ciências da Saúde (, 2017.
  80. Roque Bravo, Rita; Moreira, Patrícia; Martins, Maria João; Carvalho, Félix; Bastos, Maria de Lourdes; Carmo, Helena; Dias da Silva, Diana. "In vitro hepatotoxicity of two new psychoactive benzofurans (5-APB and 6-APB) used as recreational drugs". Paper presented in V Encontro Anual da Sociedade Portuguesa para o Estudo da Criança Abusada e Negligenciada (SPECAN), II Encontro Anual da Associação Portuguesa de Ciências Forenses (APCF) e Jornadas Científicas de Ciências do Instituto Universitário de Ciências da Saúde (, 2017.
  81. Martins, Maria João; Moreira, Patrícia; Roque Bravo, Rita; Carmo, Helena; Carvalho, Félix; Bastos, Maria de Lourdes; Dinis-Oliveira, Ricardo Jorge; Dias da Silva, Diana. "Ethanol additively enhanced cardiotoxicity of cocaine in vitro through oxidative damage and energetic deregulation". Paper presented in V Encontro Anual da Sociedade Portuguesa para o Estudo da Criança Abusada e Negligenciada (SPECAN), II Encontro Anual da Associação Portuguesa de Ciências Forenses (APCF) e Jornadas Científicas de Ciências do Instituto Universitário de Ciências da Saúde (, 2017.
  82. Enea, Maria; Dias da Silva, Diana; Pereira, Eulália; Carmo, Helena; Bastos, Maria de Lourdes. "The toxicity of gold nanoparticles and the effect of size, shape and capping agent". Paper presented in nanoPT – International Conference on Nanoscience and Nanotechnology, 2017.
  83. Martins, Maria João; Pinto, Ana; Roque Bravo, Rita; Dinis-Oliveira, Ricardo Jorge; Dias da Silva, Diana. "Prediction of hepatotoxicity of the mixture of cocaine and heroin (speedball)". Paper presented in ). IV Encontro Anual da Sociedade Portuguesa para o Estudo da Criança Abusada e Negligenciada (SPECAN) e I Encontro Anual da Associação Portuguesa de Ciências Forenses (APCF), 2016.
  84. Roque Bravo, Rita; Martins, Maria João; Pinto, Ana; Valente, Maria João; Carvalho, Félix; Bastos, Maria de Lourdes; Carmo, Helena; Dias da Silva, Diana. "Emerging club drugs: in vitro hepatotoxicity of six synthetic cathinones and benzofurans". Paper presented in LII Congresso da Sociedade Europeia de Toxicologia (EUROTOX), 2016.
  85. Dias da Silva, Diana; Costa, Joana; Enea, Maria; Pereira, Eulália; Carmo, Helena; Bastos, Maria de Lourdes. "In vitro and in vivo evaluation of the influence of size and capping agent on biodistribution and toxicity of sphere- and star-shaped nanoparticles". Paper presented in III Conferência Internacional de Toxicologia Ocupacional e Ambiental (ICOETox 2016) e III Encontro Ibero-Americano em Toxicologia e Saúde Ambiental (IBAMTOX 2016), 2016.
  86. Pinto, Ana; Martins, Maria João; Roque Bravo, Rita; Dinis-Oliveira, Ricardo Jorge; Dias da Silva, Diana. "Toxicological mixture effects of drugs of distinct pharmacological classes in rat primary hepatocytes". Paper presented in IJUP 2016 – 9.º Encontro de Jovens Investigadores da U.PORTO, 2016.
  87. Enea, Maria; Costa, Joana; Dias da Silva, Diana; Pereira, Eulália; Carmo, Helena; Bastos, Maria de Lourdes. "Synthesis, characterization, biodistribution and toxicological evaluation of star-shaped gold nanoparticles. Influence of size, shape, and capping agent". Paper presented in nanoPT – International Conference on Nanoscience and Nanotechnology, 2016.
  88. Roque Bravo, Rita; Martins, Maria João; Pinto, Ana; Valente, Maria João; Carmo, Helena; Dias da Silva, Diana. "‘Legal highs’ and ‘smart drugs’: hepatotoxicity of six emerging club drugs". Paper presented in IV Encontro Anual da Sociedade Portuguesa para o Estudo da Criança Abusada e Negligenciada (SPECAN) e I Encontro Anual da Associação Portuguesa de Ciências Forenses (APCF), 2016.
  89. Pinto, Ana; Martins, Maria João; Roque Bravo, Rita; Dinis-Oliveira, Ricardo Jorge; Dias da Silva, Diana. "Toxicological mixture effects of drugs with different mechanisms of action". Paper presented in IV Encontro Anual da Sociedade Portuguesa para o Estudo da Criança Abusada e Negligenciada (SPECAN) e I Encontro Anual da Associação Portuguesa de Ciências Forenses (APCF), 2016.
  90. Martins, Maria João; Pinto, Ana Cristina; Roque Bravo, Rita; Dinis-Oliveira, Ricardo Jorge; Dias da Silva, Diana. "Prediction of the hepatotoxicity of the mixture of cocaine and heroin (speedball)". Paper presented in IV Annual Meeting of the Portuguese Society for the Study of Abused and Neglected Children (SPECAN) and 1st Annual Meeting of the Portuguese Association of Forensic Sciences (APCF), 2016.
  91. Enea, Maria; Dias da Silva, Diana; Costa, Joana; Pereira, Eulália; Carmo, Helena; Bastos ML. "Synthesis, characterization and toxicological evaluation of star-shaped and sphere-shaped gold nanoparticles.". Paper presented in 1st Scientific Meeting of the Doctoral Programme in Sustainable Chemistry (PDQS), Aveiro, 2016.
  92. Enea, Maria; Dias da Silva, Diana; Costa, Joana; Pereira, Eulália; Carmo, Helena; Bastos ML. "Synthesis, characterization and toxicological evaluation of gold nanoparticles.". Paper presented in 1st Annual Meeting of Biological Science Department of Faculty of Pharmacy from University of Porto, Porto., 2016.
  93. Martins, MJ; Pinto, A; Roque-Bravo, R.; Carmo, H; Carvalho, F; Bastos, ML; Dinis-Oliveira, Ricardo Jorge; Dias da Silva, Diana. "Cocaine combined with heroin/morphine or ethanol disrupts mitochondrial and oxidative homeostasis.". Paper presented in LII Congresso da Sociedade Europeia de Toxicologia (EUROTOX), 2016.
  94. Moreira, Patrícia; Cunha, Sara; Dias da Silva, Diana; Carmo, Helena. "Development and validation of a method for the simultaneous determination of two piperazines used as drugs of abuse". Paper presented in IJUP – 8.º Encontro de Jovens Investigadores da U.PORTO, 2015.
    10.1016/j.toxlet.2016.06.2029
  95. Arbo, M; Dias da Silva, Diana; Valente, MJ; Bastos, ML; Carmo, H. "Comparison of three different in vitro models for the evaluation of the hepatotoxicity of piperazine designer drugs". Paper presented in LI Congresso da Sociedade Europeia de Toxicologia (EUROTOX), 2015.
  96. Dias da Silva, Diana; Silva, MJ; Araújo, AM; Valente, MJ; Carmo, H. "Mixtures of benzylpiperazine (BZP) and 3-trifluoromethylphenylpiperazine (TFMPP) elicit hepatotoxic effects in human HepaRG cells and primary rat hepatocytes". Paper presented in LI Congresso da Sociedade Europeia de Toxicologia (EUROTOX), 2015.
  97. Cammarano, ID; Carmo, H; Silva, E; Dias da Silva, Diana. "Neurotoxic mixture effects of amphetamines, alcohol, tobacco and caffeine in SHSY-5Y dopaminergic cells – the effect of temperature". Paper presented in LI Congresso da Sociedade Europeia de Toxicologia (EUROTOX), 2015.
  98. Dias da Silva, Diana; Ponte, F; Moniz, T; Carmo, H; Carvalho, F; Remião, F; Rangel, M; Bastos, ML. "Zinc (II) 3-hydroxy-4-pyridinones as potential agents for Diabetes mellitus: Evaluation of toxicity and efficacy in HepG2, Caco-2, and 3T3-L1 cells". Paper presented in LI Congresso da Sociedade Europeia de Toxicologia (EUROTOX), 2015.
  99. Cammarano, Inèz Duran; Carmo, Helena; Silva, Elisabete; Dias da Silva, Diana. "Neurotoxicity induced by mixtures of amphetamine-type stimulants with alcohol, tobacco and caffeine in SHSY-5Y cells – The impact of hyperthermia". Paper presented in IV ED-FMUP, 2014.
  100. Cammarano, Inèz Duran; Dias da Silva, Diana; Carmo, Helena. "How to assess combination effects between ecstasy and often co-consumed licit substances?". Paper presented in IJUP – 7.º Encontro de Jovens Investigadores da U.PORTO, 2014.
  101. Ferreira, Ana Maria; Dias da Silva, Diana; Carmo, Helena. "Predicting the neurotoxicity of mixtures of piperazine drugs of abuse using the SH-SY5Y neuroblastoma cells". Paper presented in cells IJUP – 7.º Encontro de Jovens Investigadores da U.PORTO, 2014.
  102. Araújo, Ana Margarida; Valente, Maria João; Dias da Silva, Diana; Carvalho, Márcia; Gaspar, Helena; Carvalho, Félix; Bastos, Maria de Lourdes; Guedes de Pinho, Paula. "Potential hepatotoxicity caused by synthetic cathinones acquired in ¿smartshops¿". Paper presented in IJUP¿2014 - 7º Encontro de Jovens Investigadores da U.PORTO, 2014.
  103. Dias da Silva, Diana; Carmo, Helena; Silva, Elisabete. "Predictability of Independent Action (IA) and Concentration Addition (CA) models on amphetamine designer drugs combination effects". Paper presented in I ED-FMUP, 2011.
Journal article
  1. Monteiro, Vânia; Dias da Silva, Diana; Martins, Marta; Guedes de Pinho, Paula; Pinto, Joana. "Metabolomics perspectives of the ecotoxicological risks of polycyclic aromatic hydrocarbons: A scoping review". Environmental Research (2024): 118394. http://dx.doi.org/10.1016/j.envres.2024.118394.
    10.1016/j.envres.2024.118394
  2. Madureira-Carvalho, Áurea; Gomes, Nelson; Dias da Silva, Diana; Azevedo, Rui; Fernandes, Luís; Dinis-Oliveira, Ricardo; Caldas, Inês. "The Code of Ethics and Conduct for Forensic Specialists: A Framework from The Portuguese Association of Forensic Sciences". Forensic Sciences 3 1 (2023): 169-178. http://dx.doi.org/10.3390/forensicsci3010013.
    10.3390/forensicsci3010013
  3. Roque-Bravo, Rita; Silva, Rafaela Sofia; Malheiro, Rui F.; Carmo, Helena; Carvalho, Félix; Dias da Silva, Diana; Silva, João Pedro. "Synthetic Cannabinoids: A Pharmacological and Toxicological Overview". Annual Review of Pharmacology and Toxicology 63 1 (2023): 187-209. http://dx.doi.org/10.1146/annurev-pharmtox-031122-113758.
    10.1146/annurev-pharmtox-031122-113758
  4. Martins, A.; da Silva, D.D.; Silva, R.; Carvalho, F.; Guilhermino, L.. "Warmer water, high light intensity, lithium and microplastics: Dangerous environmental combinations to zooplankton and Global Health?". Science of the Total Environment 854 (2023): http://www.scopus.com/inward/record.url?eid=2-s2.0-85138205240&partnerID=MN8TOARS.
    10.1016/j.scitotenv.2022.158649
  5. Peden, Amy E; Cullen, Patricia; Francis, Kate Louise; Moeller, Holger; Peden, Margaret M; Ye, Pengpeng; Tian, Maoyi; et al. "Adolescent transport and unintentional injuries: a systematic analysis using the Global Burden of Disease Study 2019". The Lancet Public Health 7 8 (2022): e657-e669. http://dx.doi.org/10.1016/s2468-2667(22)00134-7.
    10.1016/s2468-2667(22)00134-7
  6. Haagsma, Juanita A.; Charalampous, Periklis; Ariani, Filippo; Gallay, Anne; Moesgaard Iburg, Kim; Nena, Evangelia; Ngwa, Che Henry; et al. "The burden of injury in Central, Eastern, and Western European sub-region: a systematic analysis from the Global Burden of Disease 2019 Study". Archives of Public Health 80 1 (2022): http://dx.doi.org/10.1186/s13690-022-00891-6.
    10.1186/s13690-022-00891-6
  7. Janoušek, Jirí; Pilarová, Veronika; Macáková, Katerina; Nomura, Anderson; Veiga-Matos, Jéssica; Silva, Diana Dias da; Remião, Fernando; et al. "Vitamin D: sources, physiological role, biokinetics, deficiency, therapeutic use, toxicity, and overview of analytical methods for detection of vitamin D and its metabolites". Critical Reviews in Clinical Laboratory Sciences 59 8 (2022): 517-554. http://dx.doi.org/10.1080/10408363.2022.2070595.
    10.1080/10408363.2022.2070595
  8. Roque Bravo, Rita; Faria, Ana Carolina; Brito-da-Costa, Andreia Machado; Carmo, Helena; Mladenka, Premysl; Dias da Silva, Diana; Remião, Fernando. Corresponding author: Dias da Silva, Diana. "Cocaine: An Updated Overview on Chemistry, Detection, Biokinetics, and Pharmacotoxicological Aspects including Abuse Pattern". Toxins 14 4 (2022): 278. http://dx.doi.org/10.3390/toxins14040278.
    10.3390/toxins14040278
  9. Nichols, Emma; Steinmetz, Jaimie D; Vollset, Stein Emil; Fukutaki, Kai; Chalek, Julian; Abd-Allah, Foad; Abdoli, Amir; et al. "Estimation of the global prevalence of dementia in 2019 and forecasted prevalence in 2050: an analysis for the Global Burden of Disease Study 2019". The Lancet Public Health 7 2 (2022): e105-e125. http://dx.doi.org/10.1016/s2468-2667(21)00249-8.
    10.1016/s2468-2667(21)00249-8
  10. Nichols, Emma; Steinmetz, Jaimie D; Vollset, Stein Emil; Fukutaki, Kai; Chalek, Julian; Abd-Allah, Foad; Abdoli, Amir; et al. "Estimation of the global prevalence of dementia in 2019 and forecasted prevalence in 2050: an analysis for the Global Burden of Disease Study 2019". The Lancet Public Health 7 2 (2022): e105-e125. http://dx.doi.org/10.1016/s2468-2667(21)00249-8.
    Published • 10.1016/s2468-2667(21)00249-8
  11. Conte, F.M.; Cestonaro, L.V.; Piton, Y.V.; Guimarães, N.; Garcia, S.C.; Dias da Silva, D.; Arbo, M.D.. "Toxicity of pesticides widely applied on soybean cultivation: Synergistic effects of fipronil, glyphosate and imidacloprid in HepG2 cells". Toxicology in Vitro 84 (2022): http://www.scopus.com/inward/record.url?eid=2-s2.0-85134750695&partnerID=MN8TOARS.
    10.1016/j.tiv.2022.105446
  12. Castelpietra, G.; Knudsen, A.K.S.; Agardh, E.E.; Armocida, B.; Beghi, M.; Iburg, K.M.; Logroscino, G.; et al. "The burden of mental disorders, substance use disorders and self-harm among young people in Europe, 1990–2019: Findings from the Global Burden of Disease Study 2019". The Lancet Regional Health - Europe 16 (2022): http://www.scopus.com/inward/record.url?eid=2-s2.0-85126962943&partnerID=MN8TOARS.
    10.1016/j.lanepe.2022.100341
  13. Bryazka, D.; Reitsma, M.B.; Griswold, M.G.; Abate, K.H.; Abbafati, C.; Abbasi-Kangevari, M.; Abbasi-Kangevari, Z.; et al. "Population-level risks of alcohol consumption by amount, geography, age, sex, and year: a systematic analysis for the Global Burden of Disease Study 2020". The Lancet 400 10347 (2022): 185-235. http://www.scopus.com/inward/record.url?eid=2-s2.0-85134328270&partnerID=MN8TOARS.
    10.1016/S0140-6736(22)00847-9
  14. Martins, A.; da Silva, D.D.; Silva, R.; Carvalho, F.; Guilhermino, L.. "Long-term effects of lithium and lithium-microplastic mixtures on the model species Daphnia magna: Toxicological interactions and implications to ‘One Health’". Science of the Total Environment 838 (2022): http://www.scopus.com/inward/record.url?eid=2-s2.0-85130210720&partnerID=MN8TOARS.
    10.1016/j.scitotenv.2022.155934
  15. Armocida, B.; Monasta, L.; Sawyer, S.; Bustreo, F.; Segafredo, G.; Castelpietra, G.; Ronfani, L.; et al. "Burden of non-communicable diseases among adolescents aged 10–24 years in the EU, 1990–2019: a systematic analysis of the Global Burden of Diseases Study 2019". The Lancet Child and Adolescent Health 6 6 (2022): 367-383. http://www.scopus.com/inward/record.url?eid=2-s2.0-85129527829&partnerID=MN8TOARS.
    10.1016/S2352-4642(22)00073-6
  16. Dias da Silva, Diana. Corresponding author: Dias da Silva, Diana. "Synthetic Cannabinoids: A Pharmacological and Toxicological Overview". Annual Review of Pharmacology and Toxicology (IF 16.459; 2021) (2022):
    Accepted • https://doi.org/10.1146/annurev-pharmtox-031122- 113758
  17. Dias da Silva, Diana; Silva, João P.; Carmo, Helena; Carvalho, Félix. Corresponding author: Dias da Silva, Diana. "Neurotoxicity of psychoactive substances: A mechanistic overview". Current Opinion in Toxicology 28 (2021): 76-83. http://dx.doi.org/10.1016/j.cotox.2021.10.002.
    10.1016/j.cotox.2021.10.002
  18. Roque Bravo, Rita; Carmo, Helena; Valente, Maria João; Silva, João Pedro; Carvalho, Félix; Bastos, Maria de Lourdes; Dias da Silva, Diana. Corresponding author: Dias da Silva, Diana. "4-Fluoromethamphetamine (4-FMA) induces in vitro hepatotoxicity mediated by CYP2E1, CYP2D6, and CYP3A4 metabolism". Toxicology 463 (2021): 152988. http://dx.doi.org/10.1016/j.tox.2021.152988.
    10.1016/j.tox.2021.152988
  19. Ward, Joseph L; Azzopardi, Peter S; Francis, Kate Louise; Santelli, John S; Skirbekk, Vegard; Sawyer, Susan M; Kassebaum, Nicholas J; et al. "Global, regional, and national mortality among young people aged 10–24 years, 1950–2019: a systematic analysis for the Global Burden of Disease Study 2019". The Lancet 398 10311 (2021): 1593-1618. http://dx.doi.org/10.1016/s0140-6736(21)01546-4.
    10.1016/s0140-6736(21)01546-4
  20. Paulson, Katherine R; Kamath, Aruna M; Alam, Tahiya; Bienhoff, Kelly; Abady, Gdiom Gebreheat; Abbas, Jaffar; Abbasi-Kangevari, Mohsen; et al. "Global, regional, and national progress towards Sustainable Development Goal 3.2 for neonatal and child health: all-cause and cause-specific mortality findings from the Global Burden of Disease Study 2019". The Lancet 398 10303 (2021): 870-905. http://dx.doi.org/10.1016/s0140-6736(21)01207-1.
    10.1016/s0140-6736(21)01207-1
  21. Langa, Ivan; Tiritan, Maria Elizabeth; Silva, Diana; Ribeiro, Cláudia. "Gas Chromatography Multiresidue Method for Enantiomeric Fraction Determination of Psychoactive Substances in Effluents and River Surface Waters". Chemosensors 9 8 (2021): 224. http://dx.doi.org/10.3390/chemosensors9080224.
    10.3390/chemosensors9080224
  22. Gomes, Nelson G.M.; Madureira-Carvalho, Áurea; Dias-da-Silva, Diana; Valentão, Patrícia; Andrade, Paula B.. "Biosynthetic versatility of marine-derived fungi on the delivery of novel antibacterial agents against priority pathogens". Biomedicine & Pharmacotherapy 140 (2021): 111756. http://dx.doi.org/10.1016/j.biopha.2021.111756.
    10.1016/j.biopha.2021.111756
  23. Lobato-Freitas, Carolina; Brito-da-Costa, Andreia Machado; Dinis-Oliveira, Ricardo Jorge; Carmo, Helena; Carvalho, Félix; Silva, João Pedro; Dias-da-Silva, Diana. Corresponding author: Dias-da-Silva, Diana. "Overview of Synthetic Cannabinoids ADB-FUBINACA and AMB-FUBINACA: Clinical, Analytical, and Forensic Implications". Pharmaceuticals 14 3 (2021): 186. http://dx.doi.org/10.3390/ph14030186.
    10.3390/ph14030186
  24. Roque Bravo, Rita; Carmo, Helena; Valente, Maria João; Silva, João Pedro; Carvalho, Félix; Bastos, Maria de Lourdes; Dias da Silva, Diana. Corresponding author: Dias da Silva, Diana. "From street to lab: in vitro hepatotoxicity of buphedrone, butylone and 3,4-DMMC". Archives of Toxicology (2021): http://dx.doi.org/10.1007/s00204-021-02990-9.
    10.1007/s00204-021-02990-9
  25. Brito-da-Costa, Andreia Machado; Dias-da-Silva, Diana; Gomes, Nelson G. M.; Dinis-Oliveira, Ricardo Jorge; Madureira-Carvalho, Áurea. Corresponding author: Dias-da-Silva, Diana. "Pharmacokinetics and Pharmacodynamics of Salvinorin A and Salvia divinorum: Clinical and Forensic Aspects". Pharmaceuticals 14 2 (2021): 116. http://dx.doi.org/10.3390/ph14020116.
    10.3390/ph14020116
  26. Enea, Maria; Pereira, Eulália; Costa, Joana; Soares, Maria Elisa; Dias da Silva, Diana; Bastos, Maria de Lourdes; Carmo, Helena Ferreira. "Cellular uptake and toxicity of gold nanoparticles on two distinct hepatic cell models". Toxicology in Vitro 70 (2021): 105046. http://dx.doi.org/10.1016/j.tiv.2020.105046.
    10.1016/j.tiv.2020.105046
  27. Gomes, Telma Marisa; Dias da Silva, Diana; Carmo, Helena; Carvalho, Félix; Silva, João Pedro. "Epigenetics and the endocannabinoid system signaling: An intricate interplay modulating neurodevelopment". Pharmacological Research 162 (2020): 105237. http://dx.doi.org/10.1016/j.phrs.2020.105237.
    10.1016/j.phrs.2020.105237
  28. Patrícia, Moreira; Diana Dias da, Silva; Sara, Cunha; Maria de Lourdes, Bastos; Helena, Carmo. "Development and Validation of a GC-MS Method for the Simultaneous Quantification of Two Piperazine Designer Drugs Sold in Combination as 'Legal X'". Annals of Toxicology 2 1 (2020): http://dx.doi.org/10.36959/736/635.
    Published • 10.36959/736/635
  29. Patrícia, Moreira; Dias da Silva, Diana; Sara, Cunha; Maria de Lourdes, Bastos; Helena, Carmo. "Development and Validation of a GC-MS Method for the Simultaneous Quantification of Two Piperazine Designer Drugs Sold in Combination as 'Legal X'". Annals of Toxicology 2 1 (2020): http://dx.doi.org/10.36959/736/635.
    10.36959/736/635
  30. Andreia Machado Brito-da-Costa; Dias da Silva, Diana; Nelson G. M. Gomes; Ricardo Jorge Dinis-Oliveira; Áurea Madureira-Carvalho. Corresponding author: Dias da Silva, Diana. "Toxicokinetics and Toxicodynamics of Ayahuasca Alkaloids N,N-Dimethyltryptamine (DMT), Harmine, Harmaline and Tetrahydroharmine: Clinical and Forensic Impact". Pharmaceuticals 13 11 (2020): 334-334. https://doi.org/10.3390/ph13110334.
    10.3390/ph13110334
  31. Vos, Theo; Lim, Stephen S; Abbafati, Cristiana; Abbas, Kaja M; Abbasi, Mohammad; Abbasifard, Mitra; Abbasi-Kangevari, Mohsen; et al. "Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019". The Lancet 396 10258 (2020): 1204-1222. http://dx.doi.org/10.1016/s0140-6736(20)30925-9.
    10.1016/s0140-6736(20)30925-9
  32. Lozano, Rafael; Fullman, Nancy; Mumford, John Everett; Knight, Megan; Barthelemy, Celine M; Abbafati, Cristiana; Abbastabar, Hedayat; et al. "Measuring universal health coverage based on an index of effective coverage of health services in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019". The Lancet 396 10258 (2020): 1250-1284. http://dx.doi.org/10.1016/s0140-6736(20)30750-9.
    10.1016/s0140-6736(20)30750-9
  33. Murray, Christopher J L; Aravkin, Aleksandr Y; Zheng, Peng; Abbafati, Cristiana; Abbas, Kaja M; Abbasi-Kangevari, Mohsen; Abd-Allah, Foad; et al. "Global burden of 87 risk factors in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019". The Lancet 396 10258 (2020): 1223-1249. http://dx.doi.org/10.1016/s0140-6736(20)30752-2.
    10.1016/s0140-6736(20)30752-2
  34. Wang, Haidong; Abbas, Kaja M; Abbasifard, Mitra; Abbasi-Kangevari, Mohsen; Abbastabar, Hedayat; Abd-Allah, Foad; Abdelalim, Ahmed; et al. "Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries and territories, 1950–2019: a comprehensive demographic analysis for the Global Burden of Disease Study 2019". The Lancet 396 10258 (2020): 1160-1203. http://dx.doi.org/10.1016/s0140-6736(20)30977-6.
    10.1016/s0140-6736(20)30977-6
  35. Murray, Christopher J L; Abbafati, Cristiana; Abbas, Kaja M; Abbasi, Mohammad; Abbasi-Kangevari, Mohsen; Abd-Allah, Foad; Abdollahi, Mohammad; et al. "Five insights from the Global Burden of Disease Study 2019". The Lancet 396 10258 (2020): 1135-1159. http://dx.doi.org/10.1016/s0140-6736(20)31404-5.
    10.1016/s0140-6736(20)31404-5
  36. Lozano, Rafael; Fullman, Nancy; Mumford, John Everett; Knight, Megan; Barthelemy, Celine M; Abbafati, Cristiana; Abbastabar, Hedayat; et al. "Measuring universal health coverage based on an index of effective coverage of health services in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019". The Lancet 396 10258 (2020): 1250-1284. http://dx.doi.org/10.1016/s0140-6736(20)30750-9.
    10.1016/s0140-6736(20)30750-9
  37. James, Spencer L; Castle, Chris D; Dingels, Zachary V; Fox, Jack T; Hamilton, Erin B; Liu, Zichen; Roberts, Nicholas L S; et al. "Estimating global injuries morbidity and mortality: methods and data used in the Global Burden of Disease 2017 study". Injury Prevention 26 Supp 1 (2020): i125-i153. http://dx.doi.org/10.1136/injuryprev-2019-043531.
    10.1136/injuryprev-2019-043531
  38. João Alexandre; Rui Malheiro; Diana Dias da Silva; Carmo H; Félix Carvalho; João P. Silva. "The Synthetic Cannabinoids THJ-2201 and 5F-PB22 Enhance In Vitro CB1 Receptor-Mediated Neuronal Differentiation at Biologically Relevant Concentrations". International Journal of Molecular Sciences (2020): https://www.mdpi.com/1422-0067/21/17/6277.
    10.3390/ijms21176277
  39. Ana Carolina Faria; Helena Carmo; Félix Carvalho; João Pedro Silva; Maria de Lourdes Bastos; Diana Dias da Silva. Corresponding author: Diana Dias da Silva. "Drinking to death: Hyponatraemia induced by synthetic phenethylamines". Drug and Alcohol Dependence 212 (2020): 108045-108045. https://doi.org/10.1016/j.drugalcdep.2020.108045.
    10.1016/j.drugalcdep.2020.108045
  40. James, Spencer L; Castle, Chris D; Dingels, Zachary V; Fox, Jack T; Hamilton, Erin B; Liu, Zichen; S Roberts, Nicholas L; et al. "Global injury morbidity and mortality from 1990 to 2017: results from the Global Burden of Disease Study 2017". Injury Prevention 26 Supp 1 (2020): i96-i114. http://dx.doi.org/10.1136/injuryprev-2019-043494.
    10.1136/injuryprev-2019-043494
  41. Daniela Rouxinol; Diana Dias da Silva; João Pedro Silva; Félix Carvalho; Maria de Lourdes Bastos; Helena Carmo. Corresponding author: Diana Dias da Silva. "Biodistribution and metabolic profile of 3,4-dimethylmethcathinone (3,4-DMMC) in Wistar rats through gas chromatography–mass spectrometry (GC–MS) analysis". Toxicology Letters 320 (2020): 113-123. https://doi.org/10.1016/j.toxlet.2019.10.003.
    10.1016/j.toxlet.2019.10.003
  42. Enea, Maria; Pereira, Eulália; Silva, Diana Dias; Costa, Joana; Soares, Maria Elisa; de Lourdes Bastos, Maria; Carmo, Helena; Dias da Silva, Diana; Bastos, Maria de Lourdes. "Study of the intestinal uptake and permeability of gold nanoparticles using both in vitro and in vivo approaches". Nanotechnology 31 19 (2020): 195102. http://dx.doi.org/10.1088/1361-6528/ab6dfb.
    In press • 10.1088/1361-6528/ab6dfb
  43. Daniela Sousa; Helena Carmo; Rita Roque Bravo; Félix Carvalho; Maria de Lourdes Bastos; Paula Guedes de Pinho; Diana Dias da Silva. Corresponding author: Diana Dias da Silva. "Diet aid or aid to die: an update on 2,4-dinitrophenol (2,4-DNP) use as a weight-loss product". Archives of Toxicology (2020): https://doi.org/10.1007/s00204-020-02675-9.
    10.1007/s00204-020-02675-9
  44. Roque Bravo, Rita; Carmo, Helena; Silva, João Pedro; Valente, Maria João; Carvalho, Félix; Bastos, Maria de Lourdes; Dias da Silva, Diana. Corresponding author: Dias da Silva, Diana. "Emerging club drugs: 5-(2-aminopropyl)benzofuran (5-APB) is more toxic than its isomer 6-(2-aminopropyl)benzofuran (6-APB) in hepatocyte cellular models". Archives of Toxicology 94 2 (2019): 609-629. http://dx.doi.org/10.1007/s00204-019-02638-9.
    10.1007/s00204-019-02638-9
  45. Maria Enea; Miguel Peixoto de Almeida; Peter Eaton; Diana Dias da Silva; Eulália Pereira; Maria Elisa Soares; Maria de Lourdes Bastos; Helena Carmo. "A multiparametric study of gold nanoparticles cytotoxicity, internalization and permeability using an in vitro model of blood–brain barrier. Influence of size, shape and capping agent". Nanotoxicology (2019): 1-15. https://doi.org/10.1080/17435390.2019.1621398.
    10.1080/17435390.2019.1621398
  46. Rouxinol, Daniela; Carmo, Helena; Carvalho, Félix; Bastos, Maria de Lourdes; Dias da Silva, Diana. Corresponding author: Dias da Silva, Diana. "Pharmacokinetics, pharmacodynamics, and toxicity of the new psychoactive substance 3,4-dimethylmethcathinone (3,4-DMMC)". Forensic Toxicology 38 1 (2019): 15-29. http://dx.doi.org/10.1007/s11419-019-00494-x.
    10.1007/s11419-019-00494-x
  47. Dias da Silva, Diana; Ferreira, Bárbara; Roque Bravo, Rita; Rebelo, Rita; Duarte de Almeida, Tomás; Valente, Maria João; Silva, João Pedro; et al. Corresponding author: Diana Dias da Silva. "The new psychoactive substance 3-methylmethcathinone (3-MMC or metaphedrone) induces oxidative stress, apoptosis, and autophagy in primary rat hepatocytes at human-relevant concentrations". Archives of Toxicology 93 9 (2019): 2617-2634. http://dx.doi.org/10.1007/s00204-019-02539-x.
    Published • 10.1007/s00204-019-02539-x
  48. Dinis-Oliveira, Ricardo Jorge; Pereira, Carolina Lança; da Silva, Diana Dias. "Pharmacokinetic and Pharmacodynamic Aspects of Peyote and Mescaline: Clinical and Forensic Repercussions". Current Molecular Pharmacology 12 3 (2019): 184-194. http://dx.doi.org/10.2174/1874467211666181010154139.
    Published • 10.2174/1874467211666181010154139
  49. Rita Roque Bravo; Helena Carmo; Félix Carvalho; Maria de Lourdes Bastos; Diana Dias da Silva. Corresponding author: Diana Dias da Silva. "Benzo fur y: A new trend in the drug misuse scene". Journal of Applied Toxicology (2019): https://doi.org/10.1002/jat.3774.
    10.1002/jat.3774
  50. Bárbara Ferreira; Diana Dias da Silva; Félix Carvalho; Maria de Lourdes Bastos; Helena Carmo. Corresponding author: Diana Dias da Silva. "The novel psychoactive substance 3-methylmethcathinone (3-MMC or metaphedrone): A review". Forensic Science International 295 (2019): 54-63. https://doi.org/10.1016/j.forsciint.2018.11.024.
    10.1016/j.forsciint.2018.11.024
  51. Faria, Ana Carolina; Carmo, Helena; Teixeira, Catarina; Rouxinol, Daniela; Silva, João Pedro; Carvalho, Félix; Bastos, Maria de Lourdes; Dias da Silva, Diana. "Administration of 3,4-dimethylmethcathinone (3,4-DMMC) and methylone increases the release of antidiuretic hormone in female Wistar rats.". Toxicology Letters 314 (2019): S281-S282.
    Accepted
  52. Moniz, Tânia; Dias da Silva, Diana; Carmo, Helena; de Castro, Baltazar; de Lourdes Bastos, Maria; Rangel, Maria. Corresponding author: Dias da Silva, Diana. "Insights on the relationship between structure vs. toxicological activity of antibacterial rhodamine-labelled 3-hydroxy-4-pyridinone iron(III) chelators in HepG2 cells". Interdisciplinary Toxicology 11 3 (2018): 189-199. http://dx.doi.org/10.2478/intox-2018-0016.
    Open access • 10.2478/intox-2018-0016
  53. A.S. Oliveira; J. Pinto; P. Lopes; M. Cabral; M.L. Bastos; D. Dias da Silva; P. Guedes de Pinho. "Anticancer potential of semi-volatile compounds present in cork: Cytotoxic mixture effects in human colorectal adenocarcinoma cells". Toxicology Letters 295 (2018): S273-S273. https://doi.org/10.1016%2Fj.toxlet.2018.07.041.
    10.1016/j.toxlet.2018.07.041
  54. M.J. Martins; R.R.D.S. Bravo; H. Carmo; F. Carvalho; M.D.L. Bastos; R.J. Dinis-Oliveira; D. Dias da Silva. "Co-exposure to cocaine and ethanol induces oxidative impairment in H9c2 cardiomyocytes". Toxicology Letters 295 (2018): S269-S270. https://doi.org/10.1016%2Fj.toxlet.2018.07.031.
    10.1016/j.toxlet.2018.07.031
  55. Martins, Maria João; Roque Bravo, Rita; Enea, Maria; Carmo, Helena; Carvalho, Félix; Bastos, Maria de Lourdes; Dinis-Oliveira, Ricardo Jorge; Dias da Silva, Diana. Corresponding author: Dias da Silva, Diana. "Ethanol addictively enhances the in vitro cardiotoxicity of cocaine through oxidative damage, energetic deregulation, and apoptosis". Archives of Toxicology 92 7 (2018): 2311-2325. http://dx.doi.org/10.1007/s00204-018-2227-7.
    Published • 10.1007/s00204-018-2227-7
  56. Diana Dias da Silva. "Untangling the Intracellular Mechanisms Underlying Toxicity of Drugs of Abuse: A Review of the Detrimental Effects of New Psychoactive Substances (NPS)". Open Access Journal of Toxicology 3 1 (2018): https://doi.org/10.19080%2Foajt.2018.03.555604.
    Open access • Published • 10.19080/oajt.2018.03.555604
  57. Elsa F. Vieira; Diana Dias da Silva; Helena Carmo; Isabel M.P.L.V.O. Ferreira. "Protective ability against oxidative stress of brewers’ spent grain protein hydrolysates". Food Chemistry 228 (2017): 602-609. https://doi.org/10.1016%2Fj.foodchem.2017.02.050.
    Published • 10.1016/j.foodchem.2017.02.050
  58. Diana Dias da Silva; Maria João Silva; Patrícia Moreira; Maria João Martins; Maria João Valente; Félix Carvalho; Maria de Lourdes Bastos; Helena Carmo. Corresponding author: Diana Dias da Silva. "In vitro hepatotoxicity of ‘Legal X’: the combination of 1-benzylpiperazine (BZP) and 1-(m-trifluoromethylphenyl)piperazine (TFMPP) triggers oxidative stress, mitochondrial impairment and apoptosis". Archives of Toxicology (2017): https://doi.org/10.1007%2Fs00204-016-1777-9.
    10.1007/s00204-016-1777-9
  59. Teresa Patrícia Magalhães; Sara Cravo; Diana Dias da Silva; Ricardo Jorge Dinis-Oliveira; Carlos Afonso; Maria de Lourdes Bastos; Helena Carmo. "Quantification of Methadone and Main Metabolites in Nails". Journal of Analytical Toxicology 42 3 (2017): 192-206. https://doi.org/10.1093%2Fjat%2Fbkx099.
    Published • 10.1093/jat/bkx099
  60. Vieira, E.F.; Das Neves, J.; Vitorino, R.; Dias Da Silva, D.; Carmo, H.; Ferreira, I.M.P.L.V.O.. "Impact of in vitro gastrointestinal digestion and transepithelial transport on antioxidant and ACE-inhibitory activities of Brewer's spent yeast autolysate". Journal of Agricultural and Food Chemistry 64 39 (2016): 7335-7341. http://www.scopus.com/inward/record.url?eid=2-s2.0-84990038900&partnerID=MN8TOARS.
    Published • 10.1021/acs.jafc.6b02719
  61. Arbo, M.; Dias da Silva, Diana; Valente, M.J.; Bastos, M.L.; Carmo, H.. "Comparison of three different in vitro models for the evaluation of the hepatotoxicity of piperazine designer drugs". Toxicology Letters 238 2 (2015): S252-S253. http://dx.doi.org/10.1016/j.toxlet.2015.08.732.
    10.1016/j.toxlet.2015.08.732
  62. Dias-da-Silva, D.; Arbo, M.D.; Valente, M.J.; Bastos, M.L.; Carmo, H.. Corresponding author: Dias-da-Silva, D.. "Hepatotoxicity of piperazine designer drugs: Comparison of different in vitro models". Toxicology in Vitro 29 5 (2015): 987-996. http://dx.doi.org/10.1016/j.tiv.2015.04.001.
    10.1016/j.tiv.2015.04.001
  63. Arbo, M. D.; Silva, R.; Barbosa, D. J.; da Silva, D. Dias; Silva, S. P.; Teixeira, J. P.; Bastos, M. L.; Carmo, H.. "In vitro neurotoxicity evaluation of piperazine designer drugs in differentiated human neuroblastoma SH-SY5Y cells". Journal of Applied Toxicology 36 1 (2015): 121-130. http://dx.doi.org/10.1002/jat.3153.
    10.1002/jat.3153
  64. Ana Margarida Araújo; Maria João Valente; Diana Dias da Silva; Márcia Carvalho; Félix Carvalho; Maria de Lourdes Bastos; Paula Guedes de Pinho. "‘Smart’ but not safe: The potential hepatotoxicity of synthetic cathinones". Toxicology Letters 229 (2014): S64-S64. https://doi.org/10.1016%2Fj.toxlet.2014.06.254.
    10.1016/j.toxlet.2014.06.254
  65. Filipa Ponte; Sónia Fraga; Tânia Moniz; Diana Dias da Silva; Félix Carvalho; Helena Carmo; Fernando Remião; Maria Rangel; Maria Lourdes Bastos. "Development of insulino-mimetic zinc(II) complexes of the class 3-hydroxy-4-pyridinone ligands: In vitro cytotoxicity studies for safety assessment". Toxicology Letters 229 (2014): S55-S55. https://doi.org/10.1016%2Fj.toxlet.2014.06.226.
    10.1016/j.toxlet.2014.06.226
  66. Marcelo Arbo; Renata Silva; Daniel Barbosa; Diana Dias da Silva; Maria de Lourdes Bastos; Helena Carmo. "Piperazine designer drugs are cytotoxic to human neuroblastoma SH-SY5Y cells". Toxicology Letters 229 (2014): S54-S55. https://doi.org/10.1016%2Fj.toxlet.2014.06.225.
    10.1016/j.toxlet.2014.06.225
  67. Arbo, Marcelo Dutra; Silva, Renata; Barbosa, Daniel José; da Silva, Diana Dias; Rossato, Luciana Grazziotin; Bastos, Maria de Lourdes; Carmo, Helena. "Piperazine designer drugs induce toxicity in cardiomyoblast h9c2 cells through mitochondrial impairment". Toxicology Letters 229 1 (2014): 178-189. http://dx.doi.org/10.1016/j.toxlet.2014.06.031.
    10.1016/j.toxlet.2014.06.031
  68. Araújo, Ana Margarida; Valente, Maria João; Carvalho, Márcia; Dias da Silva, Diana; Gaspar, Helena; Carvalho, Félix; de Lourdes Bastos, Maria; Guedes de Pinho, Paula. "Raising awareness of new psychoactive substances: chemical analysis and in vitro toxicity screening of ‘legal high’ packages containing synthetic cathinones". Archives of Toxicology 89 5 (2014): 757-771. http://dx.doi.org/10.1007/s00204-014-1278-7.
    10.1007/s00204-014-1278-7
  69. da Silva DD; Silva E; Carmo H. "Combination effects of amphetamines under hyperthermia - the role played by oxidative stress.". (2014): http://europepmc.org/abstract/med/23765447.
    10.1002/jat.2889
  70. Dias da Silva, Diana; Silva, Elisabete; Carmo, Helena. "Cytotoxic effects of amphetamine mixtures in primary hepatocytes are severely aggravated under hyperthermic conditions". Toxicology in Vitro 27 6 (2013): 1670-1678. http://dx.doi.org/10.1016/j.tiv.2013.04.010.
    10.1016/j.tiv.2013.04.010
  71. Diana Dias da Silva; Elisabete Silva; Félix Carvalho; Helena Carmo. "Low concentration mixtures of MDMA and its major human metabolites induce significant toxicity to liver cells, both at physiological and hyperthermic conditions". Toxicology Letters 221 (2013): S153-S153. https://doi.org/10.1016%2Fj.toxlet.2013.05.316.
    10.1016/j.toxlet.2013.05.316
  72. Dias da Silva, Diana; Carmo, Helena; Lynch, Adam; Silva, Elisabete. "An insight into the hepatocellular death induced by amphetamines, individually and in combination: the involvement of necrosis and apoptosis". Archives of Toxicology 87 12 (2013): 2165-2185. http://dx.doi.org/10.1007/s00204-013-1082-9.
    10.1007/s00204-013-1082-9
  73. da Silva, Diana Dias; Silva, Elisabete; Carvalho, Félix; Carmo, Helena. Corresponding author: da Silva, Diana Dias. "Mixtures of 3,4-methylenedioxymethamphetamine (ecstasy) and its major human metabolites act additively to induce significant toxicity to liver cells when combined at low, non-cytotoxic concentrations". Journal of Applied Toxicology 34 6 (2013): 618-627. http://dx.doi.org/10.1002/jat.2885.
    10.1002/jat.2885
  74. Dias da Silva, Diana; Carmo, Helena; Silva, Elisabete. "The risky cocktail: what combination effects can we expect between ecstasy and other amphetamines?". Archives of Toxicology 87 1 (2012): 111-122. http://dx.doi.org/10.1007/s00204-012-0929-9.
    10.1007/s00204-012-0929-9
  75. Diana Dias-da-Silva; Helena Carmo; Elisabete Silva. "The impact of hyperthermia on the toxicity of amphetaminic mixtures". Toxicology Letters 211 (2012): S156-S157. https://doi.org/10.1016%2Fj.toxlet.2012.03.569.
    10.1016/j.toxlet.2012.03.569
  76. D. Dias-da-Silva; H. Carmo; E. Silva. "Additive join effects between ecstasy and other amphetamine-type agents in primary cultured rat hepatocytes". Toxicology Letters 205 (2011): S211-S211. https://doi.org/10.1016%2Fj.toxlet.2011.05.726.
    10.1016/j.toxlet.2011.05.726
  77. D. Silva; E. Silva; H. Carmo. "What combination effects can we expect from amphetamine designer drugs?". Toxicology Letters 196 (2010): S148-S148. https://doi.org/10.1016%2Fj.toxlet.2010.03.512.
    10.1016/j.toxlet.2010.03.512
  78. da Silva, Diana Dias; Silva, Renata; Remião, Fernando; Carvalho, Félix; de Lourdes Bastos, Maria; Silva, Elisabete; Carmo, Helena. Corresponding author: da Silva, Diana Dias. "Assessing combination effects of amphetamine designer drugs". Toxicology Letters 189 (2009): S80. http://dx.doi.org/10.1016/j.toxlet.2009.06.242.
    10.1016/j.toxlet.2009.06.242
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2021/02/17 RELEASE OF ANTIDIURETIC HORMONE (ADH) IN WISTAR RATS IN RESPONSE TO THE ADMINISTRATION OF METHYLONE AND 3,4-DMMC: THE GENDER IMPACT 51.ª Reunião da Sociedade Portuguesa de Farmacologia, 39.ª Reunião de Farmacologia Clínica e 20ª Reunião de Toxicologia
(Lisbon, Portugal)
2021/02/17 BIODISTRIBUTION AND METABOLISM OF 3,4-DIMETHYLMETHCATHINONE (3,4-DMMC) IN WISTAR RATS 51.ª Reunião da Sociedade Portuguesa de Farmacologia, 39.ª Reunião de Farmacologia Clínica e 20ª Reunião de Toxicologia
(Lisbon, Portugal)
2021/02/17 IN VIVO HEPATOTOXIC EFFECTS IN RESPONSE TO THE ADMINISTRATION OF METHYLONE AND 3,4-DMMC TO WISTAR RATS 51.ª Reunião da Sociedade Portuguesa de Farmacologia, 39.ª Reunião de Farmacologia Clínica e 20ª Reunião de Toxicologia
(Lisbon, Portugal)
2021/02/17 NEUROTOXICITY OF A SET OF SYNTHETIC CANNABINOID RECEPTOR AGONISTS IN NG108-15 CELLS 51.ª Reunião da Sociedade Portuguesa de Farmacologia, 39.ª Reunião de Farmacologia Clínica e 20ª Reunião de Toxicologia
(Lisbon, Portugal)
2021/02/17 SYNTHETIC CANNABINOIDS INCREASE AUTOPHAGIC VACUOLES IN NG108-15 CELLS: INFLUENCE OF CB1R ACTIVATION 51.ª Reunião da Sociedade Portuguesa de Farmacologia, 39.ª Reunião de Farmacologia Clínica e 20ª Reunião de Toxicologia
(Lisbon, Portugal)
2021/02/17 COMBINATION EFFECTS BETWEEN ENVIRONMENTAL CARCINOGENS IN PRIMARY RAT HEPATOCYTES 51.ª Reunião da Sociedade Portuguesa de Farmacologia, 39.ª Reunião de Farmacologia Clínica e 20ª Reunião de Toxicologia
(Lisbon, Portugal)
2020/10/24 NEUROTOXICITY OF A SET OF SYNTHETIC CANNABINOID RECEPTOR AGONISTS IN NG108-15 CELLS 2.º SIFFUP - Simpósio de Investigação da Faculdade de Farmácia da Universidade do Porto
Faculdade de Farmácia da Universidade do Porto (Porto, Portugal)
2020/09/07 The CYP2E1 metabolism increases in vitro hepatotoxicity of the synthetic psychostimulant 4-fluoromethamphetamine 15th YES (Young European Scientist) Meeting – Digital Experience
(Porto, Portugal)
2020/09/07 Paediatric intoxications in the North of Portugal between 2014 and 2018 15th YES (Young European Scientist) Meeting – Digital Experience
(Porto, Portugal)
2020/02/05 The synthetic psychostimulant 4-fluoromethamphetamine induces in vitro hepatotoxic effects, via CYP2E1 metabolism XLX Encontro Anual da Sociedade Portuguesa Farmacologia (SPF), XXXVIII Encontro Anual da Sociedade Portuguesa de Farmacologia Clínica, XIX Encontro Anual da Sociedade Portuguesa de Toxicologia
(Coimbra, Portugal)
2020/02/05 Paediatric intoxication in the North of Portugal between 2014 and 2018 XLX Encontro Anual da Sociedade Portuguesa Farmacologia (SPF), XXXVIII Encontro Anual da Sociedade Portuguesa de Farmacologia Clínica, XIX Encontro Anual da Sociedade Portuguesa de Toxicologia
(Coimbra, Portugal)
2020/02/05 ADB-FUBINACA enhances in vitro neuronal differentiation, via activation of cannabinoid receptor 1, at in vivo-relevant concentrations XLX Encontro Anual da Sociedade Portuguesa Farmacologia (SPF), XXXVIII Encontro Anual da Sociedade Portuguesa de Farmacologia Clínica, XIX Encontro Anual da Sociedade Portuguesa de Toxicologia
(Coimbra, Portugal)
2019/10/23 Insights into benzo fury toxicity: 5-(2-aminopropyl)benzofuran and 6-(2-aminopropyl)benzofuran disrupt oxidative, energetic and mitochondrial homeostasis of hepatocytes in vitro Lisbon Addictions 2019 – 3ª Conferência Europeia sobre Comportamentos e Dependências Aditivas subordinada ao tema “The future of addictions — new frontiers for policy, practice and science”
Serviço de Intervenção nos Comportamentos Aditivos e nas Dependências (SICAD); Observatório Europeu da Droga e da Toxicodependência (OEDT); ISAJE (International Society of Addiction Journal Editors) (Lisbon, Portugal)
2019/10/23 Synthetic Cannabinoids 5F-PB22 and THJ-2201 promote neuronal differentiation in neuroblastoma cells at biologically relevant concentrations Lisbon Addictions 2019 – 3ª Conferência Europeia sobre Comportamentos e Dependências Aditivas subordinada ao tema “The future of addictions — new frontiers for policy, practice and science
Serviço de Intervenção nos Comportamentos Aditivos e nas Dependências (SICAD); Observatório Europeu da Droga e da Toxicodependência (OEDT); ISAJE (International Society of Addiction Journal Editors) (Lisbon, Portugal)
2019/03/12 Nanomaterials: risk assessment for the environment and human health and safety VIII Fórum do Ambiente da Faculdade de Engenharia da Universidade do Porto (FEUP)
Núcleo de Estudantes de Engenharia do Ambiente (NEEA-FEUP) (Porto, Portugal)
2019/02 NOVEL PSYCHOACTIVE BENZOFURANS: COMPARISON OF THE TOXICITY ELICITED BY THE ISOMERS 5-APB AND 6-APB IN THREE VITRO HEPATOCYTE MODELS XLIX Encontro Anual da Sociedade Portuguesa Farmacologia (SPF), XXXVII Encontro Anual da Sociedade Portuguesa de Farmacologia Clinica, XVIII Encontro Anual da Sociedade Portuguesa de Toxicologia
(Porto, Portugal)
2019/02 THE PSYCHOSTIMULANT 3-METHYLMETHCATHINONE (3-MMC) ELICITS AUTOPHAGY AND APOPTOSIS IN PRIMARY RAT HEPATOCYTES (2019) XLIX Encontro Anual da Sociedade Portuguesa Farmacologia (SPF), XXXVII Encontro Anual da Sociedade Portuguesa de Farmacologia Clinica, XVIII Encontro Anual da Sociedade Portuguesa de Toxicologia
(Porto, Portugal)
2018/02 A multiparametric study of gold nanoparticles cytotoxicity, internationalization and permeability using an in vitro model of brain blood barrier XLVIII Encontro Anual da Sociedade Portuguesa Farmacologia (SPF), XXXVI Encontro Anual da Sociedade Portuguesa de Farmacologia Clinica, XVII Encontro Anual da Sociedade Portuguesa de Toxicologia e I Reunião de Jovens Farmacologistas Portugueses
(Lisbon, Portugal)
2018/02 Exposure of cardiomyocytes to ecstasy, in combination with benzylpiperazine, reveals potential cardiotoxic risks, especially under increased temperature conditions XLVIII Encontro Anual da Sociedade Portuguesa Farmacologia (SPF), XXXVI Encontro Anual da Sociedade Portuguesa de Farmacologia Clinica, XVII Encontro Anual da Sociedade Portuguesa de Toxicologia e I Reunião de Jovens Farmacologistas Portugueses
(Lisbon, Portugal)
2018/02 In vitro hepatotoxicity of 2,4-dinitrophenol (2,4-DNP) XLVIII Encontro Anual da Sociedade Portuguesa Farmacologia (SPF), XXXVI Encontro Anual da Sociedade Portuguesa de Farmacologia Clinica, XVII Encontro Anual da Sociedade Portuguesa de Toxicologia e I Reunião de Jovens Farmacologistas Portugueses
(Lisbon, Portugal)
2018/02 In vitro cardiotoxicity of 3,4-methylenedioxymethamphetamine (MDMA, ecstasy) combined with benzylpiperazine (BZP) in hyperthermia IJUP – 11.º Encontro de Jovens Investigadores da U.PORTO
(Porto, Portugal)
2017/02 3-Methylmethcathinone (3-MMC) elicits oxidative stress and apoptosis in primary rat hepatocytes IJUP – 10.º Encontro de Jovens Investigadores da U.PORTO.
(Porto, Portugal)
2017/02 Hepatotoxicity and cardiotoxicity of cocaine when combined with frequently co-consumed substances IJUP – 10.º Encontro de Jovens Investigadores da U.PORTO.
(Porto, Portugal)
2017/02 Toxicity of new psychoactive substances: effects of synthetic cathinones and benzofurans on in vitro hepatocyte models IJUP – 10.º Encontro de Jovens Investigadores da U.PORTO
(Porto, Portugal)
2017/02 Evaluation of the changes induced by piperazine designer drugs in the intracellular lipid profile IJUP – 10.º Encontro de Jovens Investigadores da U.PORTO
(Porto, Portugal)
2017/02 The new psychoactive substance 3-methylmethcathinone (3-MMC) induces hepatotoxicity toward primary rat hepatocytes by triggering intrinsic and extrincis apoptosis pathways XLVII Encontro Anual da Sociedade Portuguesa Farmacologia (SPF), XXXV Encontro Anual da Sociedade Portuguesa de Farmacologia Clinica e XVI Encontro Anual da Sociedade Portuguesa de Toxicologia
(Porto, Portugal)
2017/02 Hepatotoxicity of piperazine designer drugs: alterations in cholesterol biosynthesis and intracellular levels. XLVII Encontro Anual da Sociedade Portuguesa Farmacologia (SPF) XXXV Encontro Anual da Sociedade Portuguesa de Farmacologia Clinica e XVI Encontro Anual da Sociedade Portuguesa de Toxicologia. 2–4 de fevereiro de 2017
(Coimbra, Portugal)
2017/02 Toxicity of the new psychoactive substances butylone, buphedrone, 3,4-dimethylcathinone (4-FMC), 6-(aminopropyl)benzofuran (6-APB) and 5-(aminopropyl)benzofuran (5-APB) on in vitro hepatocyte models XLVII Encontro Anual da Sociedade Portuguesa Farmacologia (SPF), XXXV Encontro Anual da Sociedade Portuguesa de Farmacologia Clinica e XVI Encontro Anual da Sociedade Portuguesa de Toxicologia
(Coimbra, Portugal)
2017/02 In vitro toxicity of cocaine when combined with frequently co-consumed substances XLVII Encontro Anual da Sociedade Portuguesa Farmacologia (SPF), XXXV Encontro Anual da Sociedade Portuguesa de Farmacologia Clinica e XVI Encontro Anual da Sociedade Portuguesa de Toxicologia
(Coimbra, Portugal)
2016/07/19 Emerging club drugs: in vitro hepatotoxicity of six synthetic cathinones and benzofurans. I Encontro Anual do Departamento de Ciências Biológicas da Faculdade de Farmácia da Universidade do Porto
(Porto, Portugal)
2016/07/19 COCAINE COMBINED WITH HEROIN/MORPHINE OR ETHANOL DISRUPTS MITOCHONDRIAL AND OXIDATIVE HOMEOSTASIS. I Encontro Anual do Departamento de Ciências Biológicas da Faculdade de Farmácia da Universidade do Porto
Farmácia da Universidade do Porto (Porto, Portugal)
2016/07/19 SYNTHESIS, CHARACTERIZATION AND TOXICOLOGICAL EVALUATION OF AuNPs I Encontro Anual do Departamento de Ciências Biológicas da Faculdade de Farmácia da Universidade do Porto
Farmácia da Universidade do Porto (Porto, Portugal)
2016/02 Gold nanostars vs. gold nanospheres: synthesis, characterization, biodistribution and toxicological evaluation using in vitro and in vivo models XLVI Encontro Anual da Sociedade Portuguesa Farmacologia (SPF), XXXIV Encontro Anual da Sociedade Portuguesa de Farmacologia Clinica e XV Encontro Anual da Sociedade Portuguesa de Toxicologia.
(Porto, Portugal)
2016/02 In vitro hepatotoxicity of cocaine combined with heroin (speedball) XLVI Encontro Anual da Sociedade Portuguesa Farmacologia (SPF), XXXIV Encontro Anual da Sociedade Portuguesa de Farmacologia Clinica e XV Encontro Anual da Sociedade Portuguesa de Toxicologia.
(Porto, Portugal)
2016/02 In vitro hepatotoxicity of six synthetic cathinones and benzofurans that have been misused as ‘legal highs’ or ‘smart drugs’ XLVI Encontro Anual da Sociedade Portuguesa Farmacologia (SPF), XXXIV Encontro Anual da Sociedade Portuguesa de Farmacologia Clinica e XV Encontro Anual da Sociedade Portuguesa de Toxicologia
(Porto, Portugal)
2016/02 Cocaine and heroin act antagonistically to promote cytotoxic mixture effects in rat primary hepatocytes IJUP 2016 – 9.º Encontro de Jovens Investigadores da U.PORTO
(Porto, Portugal)
2016/02 Cytotoxicity elicited by six novel psychoactive substances in primary cultured hepatocytes IJUP 2016 – 9.º Encontro de Jovens Investigadores da U.PORTO. 17–19 fevereiro
(Porto, Portugal)
2015/02 Zinc (II) 3-hydroxy-4-pyridinones as potential agents for Diabetes mellitus: toxicity and insulino-mimetic effects in HepG2, Caco-2, and 3T3-L1 cells XLV Encontro Anual da Sociedade Portuguesa Farmacologia (SPF), XXXIII Encontro Anual da Sociedade Portuguesa de Farmacologia Clinica e XIV Encontro Anual da Sociedade Portuguesa de Toxicologia
(Lisboa, Portugal)
2015/02 Temperature affects the predictability of neurotoxic mixture effects of amphetamines, alcohol, tobacco and caffeine in SHSY-5Y dopaminergic cells. XLV Encontro Anual da Sociedade Portuguesa Farmacologia (SPF), XXXIII Encontro Anual da Sociedade Portuguesa de Farmacologia Clinica e XIV Encontro Anual da Sociedade Portuguesa de Toxicologia
(Lisbon, Portugal)
2015/02 Hepatotoxicity of mixtures of benzylpiperazine (BZP) and 3-trifluoromethylphenylpiperazine (TFMPP) in human HepaRG cells and primary rat hepatocytes. XLV Encontro Anual da Sociedade Portuguesa Farmacologia (SPF), XXXIII Encontro Anual da Sociedade Portuguesa de Farmacologia Clinica e XIV Encontro Anual da Sociedade Portuguesa de Toxicologia
(Lisbon, Portugal)
2014/12/09 Best 2013 PhD Thesis in Forensic Sciences: Toxicological interactions between amphetamine designer drugs in the context of polydrug abuse IV ED-FMUP
Universidade do Porto, Faculdade de Medicina (Porto, Portugal)
2014/02 Amphetamines, individually and combined, induce necrosis and apoptosis to liver cells depending on temperature and time of exposure XLIV Encontro Anual da Sociedade Portuguesa Farmacologia (SPF), XXVII Encontro Anual da Sociedade Portuguesa de Farmacologia Clinica e XIII Encontro Anual da Sociedade Portuguesa de Toxicologia
(Coimbra)
2014/02 In vitro evaluation of cytotoxicity of the insulino-mimetic Zinc (II) 3-hydroxy-4-pyridonato complexes in human intestinal ephithelial CACO-2 cells XLIV Encontro Anual da Sociedade Portuguesa Farmacologia (SPF), XXVII Encontro Anual da Sociedade Portuguesa de Farmacologia Clinica e XIII Encontro Anual da Sociedade Portuguesa de Toxicologia
(Coimbra, Portugal)
2014/02 Evaluation of the hepatotoxic potential of individual synthetic cathinones and ‘legal high’ mixtures in primary cultured rat hepatocytes and HepaRG cells XLIV Encontro Anual da Sociedade Portuguesa Farmacologia (SPF), XXVII Encontro Anual da Sociedade Portuguesa de Farmacologia Clinica e XIII Encontro Anual da Sociedade Portuguesa de Toxicologia
(Coimbra, Portugal)
2014/02 Potential hepatotoxicity caused by synthetic cathinones acquired in ‘smartshops’ IJUP – 7.º Encontro de Jovens Investigadores da U.PORTO
(Porto, Portugal)
2013/02 MDMA and its major human metabolites act additively eliciting toxicity to liver HepG2 cells, even at very low concentrations XLIII Encontro Anual da Sociedade Portuguesa Farmacologia (SPF), XXVI Encontro Anual da Sociedade Portuguesa de Farmacologia Clinica e XII Encontro Anual da Sociedade Portuguesa de Toxicologia
(Porto, Portugal)
2013/02 Toxicity evaluation of piperazine designer drugs in HepG2 cells XLIII Encontro Anual da Sociedade Portuguesa Farmacologia (SPF), XXVI Encontro Anual da Sociedade Portuguesa de Farmacologia Clinica e XII Encontro Anual da Sociedade Portuguesa de Toxicologia
(Porto, Portugal)
2012/03/22 Toxicological interactions between amphetamine designer drugs Reunião Científica Anual da Brunel University
Brunel University (London, United Kingdom)
2011/02/04 The risky cocktail – Combination effects between 3,4-methylenodioxymethamphetamine (ecstasy) and other amphetamine-derived drugs XLI Reunião Anual da Sociedade Portuguesa de Farmacologia, XXIX Reunião de Farmacologia Clínica e X Reunião de Toxicologia
(Coimbra, Portugal)
2010/06/16 Toxicological interactions between amphetamines: assessing combination effects Reunião Científica Anual da University College London (UCL)
University College London (UCL) (London, United Kingdom)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2022 - Current New psychoactive substances: estimation of consumption by wastewater-based epidemiology and evaluation of their (eco)toxicity
Co-supervisor of Ivan Marcelino Langa
 Doutoramento em Toxicologia (PhD)
Instituto Universitário de Ciências da Saúde, Portugal
2022 - Current Masticatory highs, their chemistry, neuropharmacology and toxicology
Supervisor of Maria Rita Branco Garcia
 Doutoramento em Toxicologia (PhD)
Instituto Universitário de Ciências da Saúde, Portugal
2021 - Current Assessment of therapeutic potential and toxicity of mitragynine and other bioactives of Mitragyna speciosa: clinical and forensic aspects
Co-supervisor of Asghar Beigi Harchegani
 Programa Doutoral em Ciências Forenses (PhD)
Universidade do Porto Faculdade de Medicina, Portugal
2021 - Current Disclosing hallucinogens’ impact on epigenetic modifications associated to aging and age-related neurodegeneration
Supervisor of Ana Carolina Morgado Faria
 Doutoramento em Ciências Farmacêuticas (PhD)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2021 - Current An ethnopharmacological approach on medicinal plants from Central Angola highlands: Phytochemical and preclinical studies
Co-supervisor of Juliandra Mariana Salumbo André
 Doutoramento em Ciências Biomédicas (PhD)
Instituto Universitário de Ciências da Saúde, Portugal
2021 - Current Traditional medicinal plants used for treatment of hypertension in Angola: Ethnobotanical studies, phytochemical characterization, and biological activity
Co-supervisor of Osvaldo António Kiende Lourenço
 Doutoramento em Ciências Biomédicas (PhD)
Instituto Universitário de Ciências da Saúde, Portugal
2020 - Current Epigenetic Signature of Addiction by Amphetamine-derived Drugs
Supervisor of Catarina Isabel Sousa Silva
 Toxicologia Analítica Clínica e Forense (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2019/09/01 - Current Unravelling the mechanisms of cannabinoid-induced epigenetic modifications in aging and age-related neurodegeneration
Supervisor of Rita Roque da Silva Bravo
 Doctoral Program in Neuroscience of the University of Porto (i- PDN-UP) (PhD)
Universidade do Porto Faculdade de Medicina, Portugal
2019/09/01 - Current Assessment of the Impact of Synthetic Cannabinoids in the Neuron-Glia Cell Communication During Neuronal Development
Co-supervisor of Rafaela Sofia Barbosa da Silva
 Doctoral Programme in Forensic Sciences (PhD)
Universidade do Porto Faculdade de Medicina, Portugal
2019/09/01 - Current Untangling psilocybin’s pharmacology, toxicity, epigenetics and gut microbiome impact: One step closer to a new antidepressant drug
Co-supervisor of Andreia Machado Brito da Costa
 Doctoral Programme in Biological Sciences Applied to Health (PhD)
Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2020 - 2022/12/16 Paediatric Poisoning in children and adolescents admitted to the Emergency Unit of the Hospital de São João (Porto, Portugal), 2010-2018
Supervisor of Diana Paiva Ferreira
 Mestrado em Medicina Legal (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2019/09/01 - 2022/11/28 In vitro neurodevelopmental deregulation induced by the synthetic cannabinoids AMB-FUBINACA, ADB-FUBINACA, AB-CHMINACA, HU-308 and THJ-2201
Supervisor of Carolina Lobato de Freitas
 Ciências Forenses (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2021 - 2022/09/05 Epigenetic effects and metabolic pathways of psilocybin and psilocin: An in vitro study
Supervisor of Sofia Lemos Martins
 Ciências Forenses (Degree)
Instituto Universitário de Ciências da Saúde, Portugal
2019 - 2021/12/16 Schizophrenia and cannabis: there is a link?
Supervisor of Ana Margarida Pina Águas
 Medicina Legal (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2019 - 2021/12/16 Crosstalk between autophagic intermediaries in neurotoxicity induced by Synthetic Cannabinoids (SC)
Supervisor of Catarina Pereira Teixeira
 Medicina Legal (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2019 - 2021/12/16 Patterns of prevalence of drug use in the college student population of University of Porto
Supervisor of Helena Rafaela Fernandes Garcia
 Medicina Legal (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2020 - 2021/10/08 Autophagy induced by synthetic cannabinoids in brain-derived NG108-15 cells
Supervisor of Helena Isabel Dourado Nóvoas da Silva Cabral
 Ciências Laboratoriais Forenses (Degree)
Instituto Universitário de Ciências da Saúde, Portugal
2018/09/01 - 2021/07/23 Patterns of illegal wildlife trade: Characterisation of environmental law violations and wildlife seizures in Portugal, 2003-2019
Supervisor of Mariana Tavares Martins
 Ciências e Técnicas Laboratoriais Forenses (Master)
Instituto Universitário de Ciências da Saúde, Portugal
2018/09/01 - 2021/07/20 Acute poisoning in children and adolescents admitted to the emergency room of the Hospital de São João (Porto, Portugal), 2014-2018
Supervisor of Marta Sofia Resende Russo
 Ciências e Técnicas Laboratoriais Forenses (Master)
Instituto Universitário de Ciências da Saúde, Portugal
2019 - 2021/05/31 Characterisation of pet abuse crimes in the Judicial District of Setúbal since 2014 – Factors conditioning the applicability of the Law 69/2014
Co-supervisor of Catarina Sofia Vieira Cardoso
 Ciências e Técnicas Laboratoriais Forenses (Master)
Instituto Universitário de Ciências da Saúde, Portugal
2018/09/01 - 2021/05/31 Characterisation of pet abuse crimes in the Judicial District of Setúbal since 2014 – Factors conditioning the applicability of the Law 69/2014
Co-supervisor of Catarina Sofia Vieira Cardoso
 Ciências e Técnicas Laboratoriais Forenses (Master)
Instituto Universitário de Ciências da Saúde, Portugal
2018 - 2020/12/04 Prediction of the in vitro mixture effects of Polycyclic Aromatic Hydrocarbons (PAHs) using the mathematical concepts of concentration addition and independent action
Supervisor of Ana Cristina Monteiro Pinto
 Toxicologia Analítica Clínica e Forense (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2018 - 2020/12/03 The role of autophagy in the neurotoxicity induced by synthetic cannabinoids
Supervisor of Rosa Patrícia Ferreira Pinto
 Medicina Legal (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2019 - 2020/07/28 Interactions between environmental carcinogens: A genotoxic and metabolomic approach (Interações entre carcinogénicos ambientais: Uma abordagem genotóxica e metabolómica)
Supervisor of Vânia Raquel da Cunha Monteiro
 Ciências Laboratoriais Forenses (Degree)
Instituto Universitário de Ciências da Saúde, Portugal
2019/10/14 - 2020/04/26 Toxicological effects of the cannabinoid agonist AMB-FUBINACA
Supervisor of Nuno Filipe Currais Morgado
 Medicina (Master)
Universidade do Algarve, Portugal
2019/10/13 - 2020/04/26 Toxicological effects of ADB-FUBINACA
Supervisor of Pedro Miguel da Silva Mendanha
 Medicina (Master)
Universidade do Algarve, Portugal
2018/09/01 - 2020 Combination effects of Polycyclic Aromatic Hydrocarbons (PAHs) ubiquitous in the environment - A metabolomic approach
Supervisor of Ana Cristina Monteiro Pinto
 Toxicologia Analítica Clínica e Forense (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2018/09/01 - 2020 Chemical and toxicological characterization of betel nut (Areca catechu)
Co-supervisor of Carla Diana da Silva Guedes
 Toxicologia Analítica Clínica e Forense (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2017/09/01 - 2019/10/21 Release of antidiuretic hormone (ADH) in response to the administration of synthetic cathinones: the impact of gender
Supervisor of Ana Carolina Morgado Faria
 Ciências Forenses (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2017/09/01 - 2019/10/17 In vivo hepatotoxicity of the new drugs of abuse 3,4- dimethylmethcathinone (3,4-DMMC) and methylone
Supervisor of Catarina Tavares Teixeira
 Medicina Legal (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2017 - 2019/10/17 In vivo cardiotoxicity of the new drug of abuse 3,4-dimethylmethcathinone (3,4-DMMC)
Supervisor of Catarina Tavares Teixeira
 Medicina Legal (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2017/09/01 - 2019/07/30 Study of the toxicokinetics of 3,4-dimethylmethcathinone (3,4-DMMC) in Wistar Rats
Co-supervisor of Daniela Cardoso Rouxinol
 Ciências Forenses (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2018 - 2019/02/19 Neurotoxic effects of a set of Synthetic Cannabinoid receptor agonists in NG108-15 cells
Co-supervisor of Maria Rita Branco Garcia
 Ciências Farmacêuticas (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2018/09/01 - 2019/01/02 The involvement of autophagy in cellular death elicited by New Psychoactive Substances (NPS)
Supervisor of Tomás Alexandre Costa da Conceição Duarte de Almeida
 Medicina (Master)
Universidade do Algarve, Portugal
2016/09/01 - 2018/10/29 The role played by oxidative stress and hyperthermia in the cardiotoxicity of MDMA combined with BZP
Supervisor of Sara Cristina Oliveira da Silva
 Medicina Legal (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2016 - 2018/09/13 Toxicity induced by a novel series of synthetic cathinone analogues
Co-supervisor of Sofia Moura Pinto Coelho
 Ciências Farmacêuticas (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2017/09/01 - 2018/08/31 Cellular mechanisms implicated in the neurotoxicity of mixtures of hallucinogens
Co-supervisor of Carolina Lança Pereira
 Ciências e Técnicas Laboratoriais Forenses (Master)
Instituto Universitário de Ciências da Saúde, Portugal
2015/09/01 - 2018/01/05 Evaluation of the influence of the metabolism on the cytotoxicity of 3-methylmethcathinone (3-MMC), commonly used as a drug of abuse
Co-supervisor
 Ciências Forenses (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2015/09/01 - 2017/12/21 Chemical identification of 2,4-dinitrophenol (2,4-DNP) by GC-MS in ´fat burners´ and studies of its in vitro hepatotoxicity
Co-supervisor of Daniela Filipa Costa e Sousa
 Ciências Forenses (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2016 - 2017/02/16 Hepatotoxicity of 3-methylmethcathinone (3-MMC)
Co-supervisor of Rita Catarina Pereira Rebelo
 Ciências Farmacêuticas (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2014 - 2016/11/08 Toxicity of mixtures of cocaine and often co-consumed substances
Supervisor of Maria João Da Costa Martins
 Toxicologia Analítica Clínica e Forense (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2014/09/01 - 2016/11/02 In Vitro Hepatotoxicity of Sinthetic Cathinones and Benzofurans Used as "Legal Highs"
Supervisor of Rita Roque da Silva Bravo
 Toxicologia Analítica Clínica e Forense (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2015 - 2016/03/03 In vitro study of intracellular uptake and intestinal permeability of metallic nanoparticles with potential interest for biomedical applications and in the food industry (Estudo in vitro da captação intracelular e da permeabilidade intestinal de nanopartículas metálicas com potencial interesse para aplicações biomédicas e na indústria alimentar)
Co-supervisor of Joana Raquel Machado Pedroso
 Ciências Farmacêuticas (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2014 - 2016/01/04 In vitro study of intracellular uptake of gold nanoparticles with potential interest for biomedical applications and in the food industry (Estudo in vitro da captação intracelular de nanopartículas de ouro com potencial interesse para aplicações biomédicas e na indústria alimentar)
Co-supervisor of Ana Rita Henriques Almeida Rodrigues
 Farmácia (Degree)
Instituto Politécnico da Guarda Escola Superior de Saúde, Portugal
2013 - 2015/10/30 Analytical study of the metabolic interactions between piperazines used as drugs of abuse (Estudo analítico das interações metabólicas entre piperazinas utilizadas como drogas de abuso)
Co-supervisor of Patrícia Raquel Reis Moreira
 Medicina Legal (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2014/09/01 - 2015/03/05 In vitro cardiotoxicity of mixtures MDMA and BZP in H9c2 cell line: comparison of normo and hyperthermia
Co-supervisor of Andreia Filipa Moreira Pereira
 Ciências Farmacêuticas (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2013/09/01 - 2015 Neurotoxicity elicited by combination of amphetamine-type stimulants with often co-consumed licit substances. Comparative performance of concentration addition and independent action models in assessing in vitro mixture effects
Supervisor of Inés Durán Cammarano
 Ciências Forenses (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2013/09/01 - 2014/11/12 Evaluation of the Influence of Metabolism on the Toxicological Interaction Between Two Piperazines Currently Used as Drugs of Abuse, Benzylpiperazine (BZP) and 1- (3-Trifluormethylphenyl) Piperazine (TFMPP) (Avaliação da influência do metabolismo na interação toxicológica entre duas piperazinas correntemente utilizadas como drogas de abuso, a Benzilpiperazina (BZP) e a 1-(3-trifluormetilfenil)piperazina (TFMPP))
Co-supervisor of Maria João Leal Ferreira Da Silva
 Toxicologia Analítica Clínica e Forense (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2013 - 2014/02/19 In vitro study of the neurotoxicity of piperazines currently used as drugs of abuse (Estudo in vitro da neurotoxicidade das piperazinas utilizadas correntemente como drogas de abuso)
Co-supervisor of Ana Maria Ferreira
 Ciências Farmacêuticas (Master)
Universidade do Porto Faculdade de Farmácia, Portugal

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2019 - 2019 XVIII Meeting of Toxicology / XXXVII Meeting of Clinical Pharmacology / XLIX Meeting of the Portuguese Society of Pharmacology (SPF) (2019/02/06 - 2019/02/08)
Meeting (Member of the Organising Committee)
 Universidade do Porto Faculdade de Farmácia, Portugal
2019 - 2019 IV Congress of the Portuguese Association of Forensic Sciences and XIII Scientific Days of the Science Department of the University Institute of Health Sciences under the theme “The clinical and forensic views on human improvement” (2019/04/11 - 2019/04/12)
Congress (Member of the Organising Committee)
 Instituto Universitário de Ciências da Saúde, Portugal
2019 - 2019 IV Congress of the Portuguese Association of Forensic Sciences and XIII Scientific Days of the Science Department of the University Institute of Health Sciences under the theme “The clinical and forensic views on human improvement” (2019/04/11 - 2019/04/12)
Congress (Member of the Scientific Committee)
 Instituto Universitário de Ciências da Saúde, Portugal
2018 - 2018 I Meeting of Young Pharmacologists held within the scope of the 17th Meeting of Toxicology / XXXVI Meeting of Clinical Pharmacology / XLVIII Meeting of the Portuguese Society of Pharmacology (SPF) (2018/02/05 - 2018/02/07)
Meeting (Member of the Organising Committee)
 Universidade do Porto Faculdade de Farmácia, Portugal
2018 - 2018 III Congress of the Portuguese Association of Forensic Sciences and X Scientific Days of the Science Department of the University Institute of Health Sciences, under the theme “The clinical and forensic views on memory” (2018/05/24 - 2018/05/25)
Congress (Member of the Organising Committee)
 Instituto Universitário de Ciências da Saúde, Portugal
2018 - 2018 III Congress of the Portuguese Association of Forensic Sciences and X Scientific Days of the Science Department of the University Institute of Health Sciences, under the theme “The clinical and forensic views on memory” (2018/05/24 - 2018/05/25)
Congress (Member of the Scientific Committee)
 Instituto Universitário de Ciências da Saúde, Portugal
2017 - 2017 II Congress of the Portuguese Association of Forensic Sciences and Scientific Days of the Science Department of the University Institute of Health Sciences under the theme “The clinical and forensic views in the diagnosis and treatment of injuries” ( (2017/03/30 - 2017/03/31)
Congress (Member of the Organising Committee)
 Instituto Universitário de Ciências da Saúde, Portugal
2006 - 2006 Scientific Congress “Community pharmacy - actuality and future”, promoted by the 5th year students of the Faculty of Pharmacy, University of Porto (2006/04/04 - 2006/04/05)
Congress (Member of the Organising Committee)
 Universidade do Porto Faculdade de Farmácia, Portugal

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2022/12/09 O impacto dos canabinoides sintéticos na metilação global do DNA durante a diferenciação neuronal de células NG108-15
(Thesis) Main arguer
 Mariana Antunes Arbia Almeida (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2022/12/06 Neuroprotection of Amphetamine and Methylphenidate psychostimulants against dopaminergic neurotoxins in an in vitro Parkinson model
(Thesis) Main arguer
 Patrícia Raquel Almeida Carneiro (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2022/07/29 Papel da metilacão do DNA no neurodesenvolvimento: interação com o sistema endocanabinoide
(Thesis) Main arguer
 Mariana Antunes Arbia de Almeida (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2022/07/27 The cardiotoxicity of targeted cancer drugs
(Thesis) Main arguer
 Tânia Filipa Gomes Castro (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2022/05/22 Abuso de Inalantes
(Thesis) Main arguer
 Gonçalo Pinto Anjo (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2020/09/16 Gold nanoparticles for fingerprint detection (Nanopartículas de ouro para detecção de marcas de dedos)
President of the jury
 Rita Maria Gonçalves Moreira (Other)
Instituto Universitário de Ciências da Saúde, Portugal
2020/09/16 Sexual harassment in digital social networks: victims and aggressors (Assédio sexual nas redes sociais digitais: vítimas e agressores)
President of the jury
 Sara Daniela Salgueirinho da Silva (Other)
Instituto Universitário de Ciências da Saúde, Portugal
2020/07/21 Process of Certification of a Ballistics Laboratory in Portugal
(Thesis) Main arguer
 Diana Catarina Teixeira Campelo (Master)
Instituto Universitário de Ciências da Saúde, Portugal
2020/05/28 Clinical and forensic aspects of ibogaine
(Thesis) Main arguer
 Ana Catarina Freitas Belo (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2020/05/28 Pharmacokinetics and Pharmacodynamics of Dextromethorphan: Clinical and Forensic Aspects
(Thesis) Main arguer
 Ana Rita Sá da Silva (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2020/03/12 Genetic basis of hypertrophic cardiomyopathy in sudden cardiac death victims
(Thesis) Main arguer
 Jennifer Nascimento Fadoni (Other)
Universidade do Porto Faculdade de Medicina, Portugal
2020/02/21 In vitro study of the granulosa cells response to activated THP-1 derived macrophages
(Thesis) Main arguer
 Ana Sofia Teixeira Magalhães (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2019/10/21 Release of antidiuretic hormone (ADH) in response to the administration of synthetic cathinones: the impact of gender
(Thesis) Main arguer
 Ana Carolina Morgado Faria (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2019/10/17 In vivo hepatotoxicity of the new drugs of abuse 3,4-dimethylmethcathinone (3,4-DMMC) and methylone
Supervisor
 Catarina Tavares Teixeira (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2019/07/30 Study of the toxicokinetics of 3,4-dimethylmethcathinone (3,4-DMMC) in Wistar Rats
Supervisor
 Daniela Cardoso Rouxinol (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2019/07/26 Search of Gun Shot Residues (GSR) from a Long Term Semi-Automatic Weapon Firing on the Face, Nostrils, Brow and Hand of the Sniper by ICP-MS Analysis (Pesquisa de Resíduos de Disparo (GSR) de Arma Longa Semi-Automática na Face, Narinas, Sobrancelha e Mão do Atirador Análise por ICP-MS)
(Thesis) Main arguer
 Patrícia Enes Carvalhosa (Master)
Instituto Universitário de Ciências da Saúde, Portugal
2019/07/23 Risk assessment of nanomaterials for application in the agrifood industry (Avaliação do risco dos nanomateriais para aplicação na indústria agroalimentar)
(Thesis) Main arguer
 Carolina Rodrigues Fontes Mota (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2019/07/15 Interactions between epigenetic mechanisms and the endocannabinoid system: implications for neurodevelopmental disorders
(Thesis) Main arguer
 Telma Marisa da Conceição Gomes (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2019/05/24 Pharmacokinetic and pharmacodynamic aspects of modafinil: clinical and forensic implications
(Thesis) Main arguer
 Ana Paula Alves de Sousa (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2019/05/24 BUPROPION: PHARMACOKINETIC, PHARMACODYNAMIC AND FORENSIC ASPECTS
(Thesis) Main arguer
 Rafaela Sá da Costa (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2018/10/29 The role played by oxidative stress and hyperthermia in the cardiotoxicity of MDMA combined with BZP
Supervisor
 Sara Cristina Oliveira da Silva (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2018/06/07 The Synthetic Cathinone a-Pyrrolidinovalerophenone (a-PVP): Pharmacokinetic and Pharmacodynamic Clinical and Forensic Aspects
(Thesis) Main arguer
 Leandro José Abreu Nóbrega (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2017/07/10 Oxidative Stress and Phototoxicity
(Thesis) Main arguer
 Brandon Lage Aguiar (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2017/06/09 Synthetic cannabinoids: pharmacokinetics, pharmacodynamics and clinical and forensic issues
(Thesis) Main arguer
 João Pedro Alves Nunes Pereira (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2017/06/09 Cannabinoids: a new therapeutic reality (Canabinoides: uma nova realidade terapêutica)
(Thesis) Main arguer
 Cristina Isabel Ribeiro Aguiar (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2017/06/09 New psychoactive substances as opioids: a complex forensic and clinical problem to face
(Thesis) Main arguer
 Ludovic Georges Mendes Ventura (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2016/11/08 Toxicity of mixtures of cocaine and often co-consumed substances
Supervisor
 Maria João da Costa Martins (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2016/11/02 In vitro hepatotoxicity of synthetic cathinones and benzofurans used as legal highs
Supervisor
 Rita Roque da Silva Bravo (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2016/07/26 Cocaine and polydrug abuse
Supervisor
 Maria João da Costa Martins (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2016/07/26 Toxicity of synthetic cathinone derivatives
Supervisor
 Rita Roque da Silva Bravo (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2015/07/28 In Vitro Methods of ADME Appraisal of Nanoparticles
(Thesis) Main arguer
 Maria Inês Martins Lobo de Araújo Correia (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2015/02/10 In Vitro Toxicity Evaluation Of Piperazine Designer Drugs
(Thesis) Arguer
 Marcelo Dutra Arbo (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal

Association member

Society Organization name Role
2020 - Current Society of Toxicology (SOT)
2019/01/18 - Current European Environmental Mutagen and Genomics Society (EEMGS) Associate
2019/01/18 - Current WHO Chemical Risk Assessment Network Associate
2019/01/18 - Current CAAT Academy - Center for Alternatives to Animal Testing Associate
2019/01/18 - Current AP Tox – Portuguese Society of Toxicology Associate
2015/01/01 - Current APCF - Portuguese Association of Forensic Sciences Secretary of the General Assembly; Coordinator of the Specialized Section on Environmental Crimes
2010/10/01 - Current Foste Visitar-me Associate
2009/02/06 - Current Portuguese Society of Pharmacology (SPF) Associate
2009/01/18 - Current EUROTOX - Federation of European Toxicologists and European Societies of Toxicology Associate
2009/01/18 - Current IUTOX - International Union of Toxicology Associate
2007/07/21 - Current Order of Pharmacists (Ordem dos Farmacêuticos (OF)) Associate

Committee member

Activity description
Role 		Institution / Organization
2021 - Current Self-Assessment Commission for A3ES Accreditation of the 2nd Cycle of Studies in Forensic Science and Laboratory Techniques
Member
 Instituto Universitário de Ciências da Saúde, Portugal
2021 - Current Self-Assessment Commission for A3ES Accreditation of the 1st Cycle of Studies in Forensic Laboratory Sciences
Member
 Instituto Universitário de Ciências da Saúde, Portugal
2020 - Current Self-Assessment Commission for A3ES Accreditation of the 3rd Cycle of Studies in Toxicology
Member
 Instituto Universitário de Ciências da Saúde, Portugal
2020 - Current committee of reviewers of Book Proposals submitted to Elsevier
Member
2019/09/01 - Current Scientific Committee of the Master in Forensic Sciences (IUCS-CESPU)
Member
 Cooperativa de Ensino Superior Politécnico e Universitário, Portugal

Conference scientific committee

Conference name Conference host
2019/11/01 - Current 2nd International Healthy Aging Summit 2020

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2020 - Current Ballistics, Arson and Explosives (Balística, Fogos e Explosivos) - 10h/year - Responsible Professor Bachelor´s degree in Forensic Laboratory Science (Licenciatura em Ciências Laboratoriais Forenses) Instituto Universitário de Ciências da Saúde, Portugal

Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2020 - Current Alcohol, drugs and drug addiction (Álcool, drogas e toxicodependências) - 4h/year Integrated Master in Medicine (Mestrado Integrado em Medicina) (Mestrado integrado) Universidade do Porto Faculdade de Medicina, Portugal
2020 - Current Pharmacology (Farmacologia) - 40h/year Instituto Politécnico de Leiria Escola Superior de Saúde, Portugal
2020 - Current Legal Medicine and Toxicology (Medicina Legal e Toxicologia) - 8h/year Degree in Biomedical Sciences (Licenciatura em Ciências Biomédicas) (Licenciatura) Instituto Universitário de Ciências da Saúde, Portugal

Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2020 - Current Arson, Explosives and Ballistics (Fogosm, Explosivos e Balística) - 10h/year - Responsible Professor Master of Science and Forensic Laboratory Techniques (Mestrado em Ciências e Técnicas Laboratoriais Forenses) Instituto Universitário de Ciências da Saúde, Portugal

Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2020 - Current Toxicological Analysis I (Análises Toxicológicas I) - 6h/year Master in Clinical and Forensic Analytical Toxicology (Mestrado em Toxicologia Analítica Clínica e Forense) (Mestrado) Universidade do Porto Faculdade de Farmácia, Portugal
2020 - Current Toxicological Analysis II (Análises Toxicológicas II) - 14h/year Master in Clinical and Forensic Analytical Toxicology (Mestrado em Toxicologia Analítica Clínica e Forense) (Mestrado) Universidade do Porto Faculdade de Farmácia, Portugal
2020 - Current Forensic Genetics (Genética Forense) - 12h/year Master of Science and Forensic Laboratory Techniques (Mestrado em Ciências e Técnicas Laboratoriais Forenses) (Mestrado) Instituto Universitário de Ciências da Saúde, Portugal

Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2019 - Current Psychoactive Substances (Substâncias Psicoativas) - 20h/year Bachelor´s degree in Forensic Laboratory Science (Licenciatura em Ciências Laboratoriais Forenses) (Licenciatura) Instituto Universitário de Ciências da Saúde, Portugal

Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2019 - Current Methodology and Project in Forensic Investigation (Metodologia e Projeto em Investigação Forense) - 5h (2019-2020); 10h/ year (since 2020) Bachelor´s degree in Forensic Laboratory Science (Licenciatura em Ciências Laboratoriais Forenses) (Licenciatura) Instituto Universitário de Ciências da Saúde, Portugal

Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2019 - Current Dissertation (Dissertação) - 40h/ year Master of Science and Forensic Laboratory Techniques (Mestrado em Ciências e Técnicas Laboratoriais Forenses) (Mestrado) Instituto Universitário de Ciências da Saúde, Portugal

Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2019 - Current Research in Biological Sciences Applied to Health (Investigação em Ciências Biológicas Aplicadas à Saúde) - 10h/year PhD in Biological Sciences Applied to Health (Doutoramento em Ciências Biológicas Aplicadas à Saúde) (Curso de doutoramento (conclusão de unidades curriculares)) Instituto Universitário de Ciências da Saúde, Portugal

Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2018 - Current Toxicology (Toxicologia) - 5h (2018-2019); 8h/year (since 2020) Specialization Course in Forensic Expertise (Curso de Especialização em Perícias Forenses) Universidade do Porto Faculdade de Medicina, Portugal
2017 - Current Clinical Toxicology (Toxicologia Clínica) - 5h (2017-18); 10h/year (since 2019) PhD in Biological Sciences Applied to Health (Doutoramento em Ciências Biológicas Aplicadas à Saúde) (Curso de doutoramento (conclusão de unidades curriculares)) Instituto Universitário de Ciências da Saúde, Portugal

Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2016 - Current Forensic Toxicology (Toxicologia Forense) - 5h (2016-2017); 6h/year (since 2017) Master of Science and Forensic Laboratory Techniques (Mestrado em Ciências e Técnicas Laboratoriais Forenses) (Mestrado) Instituto Universitário de Ciências da Saúde, Portugal

Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2014 - Current Toxicology and Toxicological Analysis (Toxicologia e Análises Toxicológicas) - 18h (2014-2015); 32/year (since 2020) Integrated Master in Pharmaceutical Sciences (Mestrado Integrado em Ciências Farmacêuticas) Universidade do Porto Faculdade de Farmácia, Portugal
2009 - Current Mechanistic Toxicology (Toxicologia Mecanística) - 16h (2009-2010); 14h (2010-2011); 40h/year (since 2020) Integrated Master in Pharmaceutical Sciences (Mestrado Integrado em Ciências Farmacêuticas) (Mestrado integrado) Universidade do Porto Faculdade de Farmácia, Portugal
2019 - 2020 Environmental Toxicology (Toxicologia Ambiental) - 2h Universidade Nova de Lisboa, Portugal

Universidade de Aveiro, Portugal

Universidade do Porto, Portugal
2017 - 2019 Drugs of Abuse (Drogas de Abuso) - 16h/ year Bachelor´s degree in Forensic Laboratory Science (Licenciatura em Ciências Laboratoriais Forenses) (Licenciatura) Instituto Universitário de Ciências da Saúde, Portugal

Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2012 - 2017 In Vitro Toxicology (Toxicologia In Vitro) - 5h/year PhD in Sustainable Chemistry (Doutoramento em Química Sustentável) (Curso de doutoramento (conclusão de unidades curriculares)) Universidade de Lisboa, Portugal

Universidade de Aveiro, Portugal

Universidade do Porto, Portugal
2011 - 2012 IE5516 Sustainable development in practice - 24h Master in Climate Change Impacts and Sustainability (Master) The Institute for the Environment, United Kingdom

Evaluation committee

Activity description
Role 		Institution / Organization Funding entity
2020 - Current International evaluation committee of projects submitted for funding to the Czech Science Foundation (the main public funding agency)
Member

Journal scientific committee

Journal title (ISSN) Publisher
2020/11 - Current Journal of Clinical Medicine (2077-0383) MDPI
2020/09 - Current Current Forensic Science Bentham Science Publishers
2020/09 - Current Forensic Sciences MDPI
2020/09 - Current Psychoactives MDPI
2019/07/01 - Current International Journal of Molecular Sciences (1422-0067) MDPI AG
2018 - Current The Natural Products Journal
2018 - Current Forensic Sciences Research
2018 - Current Ata Médica Portuguesa
2018 - Current BMC Pharmacology and Toxicology
2017 - Current Toxicology In Vitro
2017 - Current Toxicology Letters
2017 - Current Toxicology
2017 - Current Clinical and Experimental Pharmacology and Physiology
2017 - Current Journal of Ethnopharmacology
2016 - Current Case Reports in Critical Care
2015 - Current British Journal of Pharmacology
2014 - Current Cardiovascular Toxicology
2013 - Current Scientia Pharmaceutica
2013 - Current Pharmacology Research & Perspectives

Mentoring / Tutoring

Topic Student name
2020 - Current Sergio Fernandez Trujillo
2019/09/01 - Current Pesticide residue in foods: toxicological combined effects Raquel Segura Gonçalves
2018/09/01 - Current Study of the toxicokinetics of synthetic cathinones and the impact of metabolism in their nephrotoxicity Jordi Iglesies i Torrent
2011/09/01 - Current Validation of GC-MS methodologies for quantification of metabolites of amphetamines Zeynep Seda Eren
2011/09/01 - Current Mixtures of environmental pollutants Diogo Martins Nunes Fernandes
2018/09/01 - 2020/12/03 Metabolomic study of the liver exposed to novel nanomaterials Mariana Machado Pereira
2018/09/01 - 2020/11/17 Toxicity and intestinal permeability of novel nanomaterials Carolina Rodrigues Fontes Mota
2015 - 2020/11/11 Maria Enea
2015/03/15 - 2020 Evaluation of toxicological activities of novel gold nanoparticles using in vitro models of blood–brain and intestinal barriers Maria Enea
2019/03/20 - 2019/04/20 Biological properties of an Algerian Opuntia ficus indica Moussaoui Badr-Eddine
2018/09/01 - 2019 Ciências Forenses Ana Carolina Correia Torcato Carrilho
2016 - 2018/11/13 Mentoring on the assessment of phototoxicity of topical phenolic antioxidants. Brandon Lage Aguiar
2017/09/01 - 2018 Evaluation of the toxicological effects of the pesticides lambda-cyhalothrin and 3-phenoxybenzaldehyde in hepatocytes and cardiomyocytes. Bakhta Aouey
2017/06/01 - 2017/08/31 Toxicity induced by a novel series of synthetic cathinone analogues and their combinations Nico Scholz
2015/08/31 - 2016/11/17 Assessment of toxicological activities of phototoxic materials Bruna Catarina de Freitas Maciel
2016/06/01 - 2016/08/31 Cardiotoxicity elicited by combinations of drugs of abuse. Renata Bartnicka
2012/09/01 - 2016/07/14 Assessment of antioxidant activities of by-products from brewing and canned fish industry Elsa Marisa Ferreira Vieira
2012/09/01 - 2016/04/05 Assessment of toxicological activities of novel 3-hydroxy-4-pyridinone iron chelators synthesised to fight mycobacterium infection. Tânia Alexandra Fernandes de Sousa Moniz Abreu
2015/06/01 - 2015/08/07 Neurotoxicity elicited by combination of amphetamine-type stimulants with repeatedly co-consumed licit drugs Sophie Dunlop
2015/07/16 - 2015/07/31 Learning of cell culture techniques Muhammed Goda
2011/09/01 - 2015/02/10 Assessment of toxicological effects of piperazine drugs of abuse in in vitro models of the heart, brain and liver Marcelo Dutra Arbo
2014/09/01 - 2015 Cytotoxicity of BZP and MDMA in mouse embryonic fibroblast adipose-like cell line 3T3-L1 Esra Kasal
2013/09/01 - 2015 Synthesis and toxicological characterization of different types of gold nanoparticles. In vitro and in vivo studies Joana Daniela da Silva Costa
2012/09/01 - 2014/12/16 Prediction and assessment of toxicological effects of mixture of drugs contained in products sold in head shops for recreational abuse Ana Margarida Carvalho Araujo
2013/09/01 - 2014 The cytotoxicity profile of paraquat in RBE4 cells with Neutral Red Uptake Assay Enes Arica
Distinctions

Award

2020 Parallel Oral Sessions Awards (Physiology and Immunology area)
Universidade do Porto Faculdade de Medicina, Portugal
2017 Best Poster Prize 2017 - V Annual Meeting of the Portuguese Society for the Study of Abused and Neglected Children (SPECAN) and II Annual Meeting of the Portuguese Association of Forensic Sciences (APCF)
Associação Portuguesa de Ciências Forenses, Portugal
2013 Best PhD Thesis Prize 2013 - Forensic Sciences
Universidade do Porto Faculdade de Medicina, Portugal

Other distinction

2018 Outstanding Contribution Award for Forensic Sciences Research
Forensic Sciences Research (FSR), United Kingdom