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Identification

Personal identification

Full name
Ana Leitão Ferreira

Citation names

  • Ferreira, Ana Isabel Leitão

Author identifiers

Ciência ID
791E-88E5-5BD7
ORCID iD
0000-0003-2350-6947

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
French Beginner (A1) Beginner (A1) Beginner (A1) Beginner (A1)
Spanish; Castilian Intermediate (B1) Intermediate (B1) Intermediate (B1) Intermediate (B1)
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Education
Degree Classification
2014 - 2021/04/06
Concluded
 Programa Doutoral em Engenharia Biomédica (Doutoramento)
Universidade do Porto, Portugal
"Detection of loss of consciousness towards personalized anaesthesia induction and maintenance" (THESIS/DISSERTATION)
2021/04/06
Concluded
 Engenharia Biomédica (Doutoramento)
Major in Sem especialidade
Universidade do Porto Faculdade de Engenharia, Portugal
"Detection of loss of consciousness towards personalized anaesthesia induction and maintenance " (THESIS/DISSERTATION)
2008
Concluded
 Mestrado Integrado em Engenharia Biomédica (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"Avaliação de Paramentros Hemodinamicos: Laser Doppler Pontual" (THESIS/DISSERTATION)
 14
Affiliation

Science

Category
Host institution 		Employer
2012/05/21 - 2014/09/21 Researcher (Research) Instituto de Engenharia Mecanica e Gestao Industrial, Portugal
2011/10 - 2012/09 Researcher (Research) Laboratório Associado de Energia, Transportes e Aeronáutica, Portugal
2010/09/14 - 2011/06/13 Researcher (Research) Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal
2008/03/01 - 2010/07/31 Researcher (Research) Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal

Others

Category
Host institution 		Employer
2023/03/06 - Current Medical Writer PPD part of Thermo Fisher Scientific, Portugal
2022/07/14 - 2023/02/28 Medical Writer IQVIA Portugal, Portugal
2019/12/01 - 2022/02/28 Medical Writer BlueClinical, Portugal
2014/09/01 - 2021/04/06 Candidata a PhD Universidade do Porto Faculdade de Engenharia, Portugal
2011/04/01 - 2011/07/31 Estagiária Instituto Nacional de Engenharia Biomédica, Portugal
2007/06/01 - 2007/08/31 Bolseira de Iniciação à Investigação Universidade de Coimbra Departamento de Física, Portugal
2006/01/01 - 2006/03/31 Bolseira de Iniciação à Investigação Universidade de Coimbra Departamento de Física, Portugal
Projects

Grant

Designation Funders
2014/01 - Current IntelLabII - Intelligence in Laboratories
FCOMP-01-0202-FEDER-033877
 Federación Española de Enfermedades Raras
2011/11 - 2013/06 Bio-computational study of tinnitus
PTDC/SAU-BEB/104992/2008
 Fundação para a Ciência e a Tecnologia, I.P.
2010/07 - 2011/07 Neurocornea - diabetic peripheral neuropathy early diagnosis and follow-up through in vivo automatic analysis of corneal nerves morphology
PTDC/SAU-BEB/104183/2008
 Fundação para a Ciência e a Tecnologia, I.P.
2008/10 - 2010/07 In vivo corneal metabolic imaging
PTDC/SAU-BEB/73425/2006
 Fundação para a Ciência e a Tecnologia, I.P.

Other

Designation Funders
2014 - Current Detection of loss of consciousness towards personalized anesthesia induction and maintenance
SFRH/BD/98915/2013
Centro Hospitalar Universitário do Porto EPE, Portugal
Ongoing
Outputs

Publications

Book chapter
  1. Ferreira, Ana Leitão; Nunes, Catarina S.; Mendes, Joaquim Gabriel; Amorim, Pedro. "Usefulness of the Blink Reflex to Assess the Effect of Propofol During Induction of Anesthesia in Surgical Patients". In XV Mediterranean Conference on Medical and Biological Engineering and Computing – MEDICON 2019, 1057-1063. Springer International Publishing, 2019.
    10.1007/978-3-030-31635-8_128
  2. Ferreira, A. L.; Nunes, C. S.; Gabriel, J.; Amorim, P.. "The influence of two different drug infusion profiles on the pharmacodynamics model performance". In World Congress on Medical Physics and Biomedical Engineering, June 7-12, 2015, Toronto, Canada, 874-880. Cham: Springer International Publishing, 2015.
    Published • 10.1007/978-3-319-19387-8_214
  3. Ferreira, Ana; Morgado, António Miguel; Silva, José Silvestre. "Corneal nerves segmentation and morphometric parameters quantification for early detection of diabetic neuropathy". In XII Mediterranean Conference on Medical and Biological Engineering and Computing 2010, 264-267. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010.
    Published • 10.1007/978-3-642-13039-7_66
  4. Ferreira, Ana; Morgado, António Miguel; Silva, José Silvestre. "Automatic Corneal Nerves Recognition for Earlier Diagnosis and Follow-Up of Diabetic Neuropathy". In Image Analysis and Recognition, 60-69. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010.
    Published • 10.1007/978-3-642-13775-4_7
Conference abstract
  1. Ferreira, Ana Isabel Leitão. "High variability in propofol requirements for anesthesia induction". Paper presented in Congresso da Sociedade Portugues de Anesthesiologia, Figueira da Foz, 2016.
    Published
  2. Ferreira, Ana Isabel Leitão. "The observation of hysteresis in the loss and recovery of consciousness induced with propofol suggests a neural inertia in humans". Paper presented in Congresso da Sociedade Portuguesa de Anestesiologia, Figueira da Foz, 2016.
    Published
  3. Ferreira, Ana Isabel Leitão. "Using TCI and constant infusion rates in the induction of anaesthesia: a comparative study". Paper presented in Congresso da Sociedade Portuguesa de Anestesiologia, Figueira da Foz, 2016.
    Published
  4. Ferreira, Ana Isabel Leitão. "Inter-patient variability and predicted factors of propofol requirements for loss and recovery of consciousness". Paper presented in Congresso da Sociedade Portuguesa de Anestesiologia, Figueira da Foz, 2016.
    Published
  5. Ferreira, Ana Isabel Leitão. "How much and how to administer propofol in the induction phase of anesthesia?". Paper presented in Congresso da Sociedade Portuguesa de Anestesiologia, Figueira da Foz, 2016.
    Published
  6. Ferreira, Ana Isabel Leitão. "Interpatient variability of propofol requirements for anesthesia: LOC, maintenance and ROC". Paper presented in Congresso da Sociedade Portuguesa de Anestesiologia, Figueira da Foz, 2016.
    Published
  7. Ferreira, Ana Isabel Leitão. "Are the propofol effect-site concentration at LOC and ROC related?". Paper presented in Congresso da Sociedade Portuguesa de Anestesiologia, Figueira da Foz, 2016.
    Published
  8. Ferreira, Ana Isabel Leitão. "The Bispectral Index (BIS) may have a clinically significant processing time delay that may be independent of the smooting rate". Paper presented in Congresso da Sociedade Portuguesa de Anestesia, Cascais, 2015.
    Published
  9. Ferreira, Ana Isabel Leitão. "Identificação de atraso na resposta do BIS à indução da anestesia". Paper presented in Congresso da Sociedade Portuguesa de Anestesia, Cascais, 2015.
    Published
  10. Ferreira, Ana Isabel Leitão. "Propofol requirements for anesthesia induction show wide individual variability, independently of age, gender, weight and height". Paper presented in Anesthesiology 2015 Annual Meeting, San Diego, 2015.
    Published
  11. Ferreira, Ana Isabel Leitão. "Bispectral Index and Spectral Edge Frequency may have a clinically relevant processing time delay, unrelated to the smoothing rate set on the BIS monitor". Paper presented in Anesthesiology 2015 Annual Meeting, San Diego, 2015.
    Published • 10.1097/ANA.0000000000000217
  12. Ferreira, Ana Isabel Leitão. "Identification of a BIS time delay in the response to anesthesia induction". Paper presented in Anesthesiology 2015 Annual Meeting, San Diego, 2015.
    Published
Conference paper
  1. Ferreira, A.L.; Mendes, J.; Amorim, P.; Nunes, C.S.. "Neuro-fuzzy models to predict the required propofol amount for loss of consciousness during general anesthesia: A preliminary study". 2018.
    10.1109/MeMeA.2018.8438628
  2. Ferreira, A.L.; Mendes, J.; Amorim, P.; Nunes, C.S.. "EEG signatures at the transition between conscious and unconscious state during induction of general anesthesia with remifentanil and propofol". 2018.
    10.1109/MeMeA.2018.8438635
  3. Nunes, Catarina S.; Ferreira, Ana Leitão; Correia, Rui P.; Amorim, Pedro P.. "Individualized anesthesia: independent predictive factors for the propofol induction target". 2017.
  4. Ferreira, Ana Isabel Leitão. "A review of segmentation algorithms for ear image data". Paper presented in 2012 7th Iberian Conference on Information Systems and Technologies (CISTI), Madrid, 2012.
    Published
  5. Ferreira, Ana; Lamas, Joao; Gomes, Luis; Silva, Susana; Loureiro, Custodio; Domingues, Jose Paulo; Silva, Jose Silvestre; Morgado, Miguel. "neuroCornea — Diabetic peripheral neuropathy early diagnosis and follow-up through in vivo automatic analysis of corneal nerves morphology". Paper presented in 2011 1st Portuguese Meeting in Bioengineering - the Challenge of the XXI Century (ENBENG 2011), Lisbon, 2011.
    Published • 10.1109/ENBENG.2011.6026071
  6. Ferreira, Ana Isabel Leitão. "Automatic segmentation of corneal nerves structures using region growing approach". Paper presented in 5ª Conferência Ibérica de Sistemas y Tecnologias de Information (CISTI2010), Santiago de Compostela, 2010.
    Published
  7. Ferreira, Ana Isabel Leitão. "Corneal nerves identification for earlier diagnosis and followup of diabetic neuropathy". Paper presented in 15th edition of the Portuguese Conference on Pattern Recognition, Aveiro, 2009.
    Published
Journal article
  1. Ferreira, A.L.; Vide, S.; Nunes, C.S.; Neto, J.; Amorim, P.; Mendes, J.. "Implementation of Neural Networks to Frontal Electroencephalography for the Identification of the Transition Responsiveness/Unresponsiveness During Induction of General Anesthesia". IRBM 42 5 (2021): 390-397. http://dx.doi.org/10.1016/j.irbm.2021.02.004.
    Published • 10.1016/j.irbm.2021.02.004
  2. Ana Leitão Ferreira; Catarina S. Nunes; Sérgio Vide; João Felgueiras; Márcio Cardoso; Pedro Amorim; Joaquim Mendes. "Performance of blink reflex in patients during anesthesia induction with propofol and remifentanil: prediction probabilities and multinomial logistic analysis". BioMedical Engineering OnLine (2020): https://doi.org/10.1186/s12938-020-00828-6.
    10.1186/s12938-020-00828-6
  3. Ferreira, Ana; Vide, Sérgio; Felgueiras, João; Cardoso, Márcio; Nunes, Catarina; Mendes, Joaquim; Amorim, Pedro. "Electromyographic assessment of blink reflex throughout the transition from responsiveness to unresponsiveness during induction with propofol and remifentanil". Journal of Clinical Monitoring and Computing (2020): http://dx.doi.org/10.1007/s10877-020-00593-w.
    10.1007/s10877-020-00593-w
  4. Ferreira, Ana Leitão; Mendes, Joaquim; Nunes, Catarina; Amorim, Pedro. "Administração de Propofol na Indução da Anestesia Geral em Portugal". Revista Da Sociedade Portuguesa De Anestesiologia 29 1 (2020): 6-11. https://revistas.rcaap.pt/anestesiologia/article/view/18834.
    10.25751/rspa.18834
  5. Ferreira, A.L.; Correia, R.; Vide, S.; Ferreira, A.D.; Kelz, M.B.; Mendes, J.G.; Nunes, C.S.; Amorim, P.. "Patterns of Hysteresis between Induction and Emergence of Neuroanesthesia Are Present in Spinal and Intracranial Surgeries". Journal of Neurosurgical Anesthesiology 32 1 (2020): 82-89. http://www.scopus.com/inward/record.url?eid=2-s2.0-85055659954&partnerID=MN8TOARS.
    10.1097/ANA.0000000000000559
  6. Ferreira, Ana Isabel Leitão. "The blink reflex as a useful approach for assessing the effect of propofol during the induction phase of anesthesia". Journal of Neurosurgical Anesthesiology 31 4 (2019): 481-482. http://dx.doi.org/10.1097/ana.0000000000000630.
    10.1097/ana.0000000000000630
  7. Ferreira, Ana Leitão; Mendes, Joaquim Gabriel; Nunes, Catarina Sofia; Amorim, Pedro. "Avaliação do tempo de atraso do índice bispectral na resposta à indução da anestesia: estudo observacional". Brazilian Journal of Anesthesiology 69 4 (2019): 377-382. http://dx.doi.org/10.1016/j.bjan.2019.03.008.
    10.1016/j.bjan.2019.03.008
  8. Ana Leitão Ferreira; Joaquim Gabriel Mendes; Catarina Sofia Nunes; Pedro Amorim. "Evaluation of Bispectral Index time delay in response to anesthesia induction: an observational study". Brazilian Journal of Anesthesiology (English Edition) (2019): https://doi.org/10.1016/j.bjane.2019.04.006.
    10.1016/j.bjane.2019.04.006
  9. Ferreira, A.L.; Nunes, C.; Mendes, J.G.; Amorim, P.. "¿Contamos actualmente con un método fiable para detectar el momento de pérdida de consciencia durante la inducción de la anestesia?". Revista Española de Anestesiología y Reanimación 66 2 (2019): 93-103. http://dx.doi.org/10.1016/j.redar.2018.06.008.
    10.1016/j.redar.2018.06.008
  10. Ferreira, Ana Isabel Leitão. "Transition to loss of consciousness during anesthesia induction with remifentanil and propofol: EEG patterns". Journal of Neurosurgical Anesthesiology 30 4 (2018): 395-470. http://dx.doi.org/10.1097/ana.0000000000000531.
    10.1097/ana.0000000000000531
  11. Ferreira, Ana Isabel Leitão. "Towards personalized anesthesia: predictive factors for propofol requirements for loss of consciousness". Journal of Neurosurgical Anesthesiology 29 4 (2017): 490-576. http://dx.doi.org/10.1097/ana.0000000000000452.
    10.1097/ana.0000000000000452
  12. Ferreira, Ana Isabel Leitão. "Predicting loss of consciousness using the pupillary light reflex". Journal of Neurosurgical Anesthesiology 29 4 (2017): 490-576. http://dx.doi.org/10.1097/ana.0000000000000452.
    10.1097/ana.0000000000000452
  13. Ferreira, Ana Isabel Leitão. "Calculated overshoot in propofol cerebral concentration at induction showed no correlation in the observed fall in BIS or systolic pressure". Journal of Neurosurgical Anesthesiology 28 4 (2016): 451-452.
  14. Ferreira, Ana Isabel Leitão. "How expert anesthesiologists perform and understand propofol induction: results from a survey". Journal of Neurosurgical Anesthesiology 28 4 (2016): 505-506.
  15. Ferreira, Ana Isabel Leitão. "Individualizing propofol target controlled infusion (TCI) anesthesia: an addition to depth of anesthesia monitors in an attempt to prevent awareness?Journal of Neurosurgical Anesthesiology". Journal of Neurosurgical Anesthesiology 28 4 (2016): 478-478.
  16. Ferreira, Ana Isabel Leitão. "Wide inter-patient variability in metabolism measured by indirect calorimetry during general anesthesia and surgery does not influence propofol requirements". Journal of Neurosurgical Anesthesiology 28 4 (2016): 496-496.
  17. Ferreira, Ana Isabel Leitão. "Hysteresis at loss and return of consciousness with propofol anesthesia in surgical patients may be evidence of neural inertia in humans". Journal of Neurosurgical Anesthesiology 28 4 (2016): 471-472.
  18. Ferreira, Ana Isabel Leitão. "A high variability in propofol requirements for anesthesia induction is shown independently of remifentanil". Journal of Neurosurgical Anesthesiology 27 4 (2015): 431-432. http://dx.doi.org/10.1097/ana.0000000000000217.
    10.1097/ana.0000000000000217
  19. Ferreira, Ana Isabel Leitão. "Using the calculated propofol concentration at the loss of consciousness as the post-induction target for TCI anesthesia, results in a significant decrease in BIS and blood pressure independently of the PK model". Journal of Neurosurgical Anesthesiology 27 4 (2015): 430-431.
    Published • 10.1097/ANA.0000000000000217
  20. Ferreira, Ana Isabel Leitão. "Anesthesia induction with propofol and remifentanil for neurosurgery: identification of a BIS time delay". Journal of Neurosurgical Anesthesiology 27 4 (2015): 432-433.
    Published • 10.1097/ANA.0000000000000217
  21. Ferreira, Ana Isabel Leitão. "Inter-patient variability and predictive factors of propofol requirements and estimated concentrations for loss of consciousness and recovery". Journal of Neurosurgical Anesthesiology 27 4 (2015): 460-461.
    Published • 10.1097/ANA.0000000000000217
  22. Ferreira, Ana Isabel Leitão. "The bispectral index (BIS) may have a clinically significant processing time delay that may be independent of the smoothing rate (SR)". European Journal of Anaesthesiology 32 53 (2015): 12-13.
    Published
  23. Ferreira, Ana; Morgado, António Miguel; Silva, José Silvestre. "A method for corneal nerves automatic segmentation and morphometric analysis". Computer Methods and Programs in Biomedicine 107 1 (2012): 53-60.
    Published • 10.1016/j.cmpb.2011.09.014
  24. Ferreira, Ana; Gentil, Fernanda; Tavares, João Manuel R. S.. "Segmentation algorithms for ear image data towards biomechanical studies". Computer Methods in Biomechanics and Biomedical Engineering 17 8 (2012): 888-904.
    Published • 10.1080/10255842.2012.723700
Activities

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2016 - Current Estudo sobre a indução da anestesia em Portugal: Análise Estatística Multivariada
Co-supervisor
 Mestrado em Estatística, Matemática e Computação da Universidade Aberta (Master)
Centro Hospitalar Universitário do Porto EPE, Portugal

Association member

Society Organization name Role
2016/01 - Current American Society of Anesthesiologists
2008/09 - 2011/09 jeKnowledge - Júnior Empresa da FCTUC
2007/11 - 2008/10 Departamento de Física da FCTUC
Distinctions

Award

2016 Melhor comunicação cientifica no Congresso da Sociedade Portuguesa de Anestesiologia
Abbvie Pharmaceuticals, Portugal
2016 SNACC Resident Research Travel Award
SNACC - The Society for Neuroscience in Anesthesiology and Critical care, Portugal
2015 Travel Grant para ida ao Annual Meeting of American Society of Anesthesiologists
FLAD - Fundação Luso-Americana, Portugal

Other distinction

2013 Bolsa Individual de Doutoramento
Fundação para a Ciência e a Tecnologia, Portugal