Identification
Personal identification
- Full name
- Vitor Manuel dos Santos Francisco
Citation names
- Francisco, Vitor
Author identifiers
- Ciência ID
- 7A1A-3400-E0A5
Email addresses
- francisco.vms@cnc.uc.pt (Professional)
Knowledge fields
- Engineering and Technology - Nano-technology
- Medical and Health Sciences - Medical Biotechnology - Biomaterials
- Exact Sciences - Chemical Sciences
Languages
Language | Speaking | Reading | Writing | Listening | Peer-review |
---|---|---|---|---|---|
English | Proficiency (C2) | Proficiency (C2) | Proficiency (C2) | Proficiency (C2) | Proficiency (C2) |
Spanish; Castilian | Advanced (C1) | Advanced (C1) | Advanced (C1) | Advanced (C1) |
Education
Degree | Classification | |
---|---|---|
2014/01/10
Concluded
|
Chemistry (Doctor)
Major in Physical Chemistry
Universidade de Santiago de Compostela, Spain
"Thermodynamic and structural studies on the interaction of guests with macrocycles" (THESIS/DISSERTATION)
|
Approved unanimously with distinction and praise |
2010/09/22
Concluded
|
Science and Technology of Colloids and Interfaces (Mestrado)
Universidade de Santiago de Compostela, Spain
"Vesículas a partir dun complexo de inclusíon entre un calixareno e un surfactante (Supramolecular vesicles formed between
a calixarene and a surfactant)" (THESIS/DISSERTATION)
|
Excellent (10.0) |
2008
Concluded
|
Chemistry (Licenciatura)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"Estudio cinético de una reacción autocatalítica: nitrosación del disulfuro de formamidina (Kinetic study of an autocatalytic
reaction: nitrosation of formamidine disulfide)" (THESIS/DISSERTATION)
|
15 |
Affiliation
Science
Category Host institution |
Employer | |
---|---|---|
2018/07/01 - Current | Contracted Researcher (Research) | Centro de Inovação em Biomedicina e Biotecnologia (CIBB), Portugal |
Centro de Inovação em Biomedicina e Biotecnologia (CIBB), Portugal | ||
2015/03/01 - 2018/06/30 | Postdoc (Research) | Centro de Inovação em Biomedicina e Biotecnologia (CIBB), Portugal |
Centro de Inovação em Biomedicina e Biotecnologia (CIBB), Portugal | ||
2014/03/15 - 2015/02/28 | Researcher (Research) | Biocant Associação de Transferência de Tecnologia, Portugal |
2013/01/01 - 2013/12/31 | Researcher (Research) | Universidade de Santiago de Compostela - Campus Vida, Spain |
2012/09/01 - 2012/11/30 | Visiting Researcher (Research) | Jacobs University Bremen gGmbH, Germany |
Teaching in Higher Education
Category Host institution |
Employer | |
---|---|---|
2022/09/01 - Current | Invited Assistant (Polytechnic Teacher) | Instituto Politécnico de Coimbra, Portugal |
Instituto Politécnico de Coimbra Instituto Superior de Engenharia de Coimbra, Portugal |
Projects
Contract
Designation | Funders | |
---|---|---|
2023/03/01 - Current | Targeted senolytic delivery system to treat liver cirrhosis
2022.02783.PTDC
Principal investigator
Centro de Inovação em Biomedicina e Biotecnologia (CIBB), Portugal
|
Fundação para a Ciência e a Tecnologia
Ongoing
|
2023/01/01 - Current | Nanomedicine and trojan cells for leukemic niche intervention
2022.05946.PTDC
Researcher
Centro de Inovação em Biomedicina e Biotecnologia (CIBB), Portugal
Universidade de Coimbra, Portugal |
Fundação para a Ciência e a Tecnologia
Ongoing
|
2022/01/01 - Current | A gene editing nanoparticle formulation for retinal degeneration diseases
EXPL/BIA-CEL/0989/2021
Co-Principal Investigator (Co-PI)
|
Fundação para a Ciência e a Tecnologia
Ongoing
|
2022/01/01 - Current | Enhancing epithelial permeability: a nanotechnology-based solution for epi-on corneal cross-linking
EXPL/BIA-BQM/0042/2021
Researcher
Universidade de Coimbra, Portugal
Centro de Inovação em Biomedicina e Biotecnologia (CIBB), Portugal |
Fundação para a Ciência e a Tecnologia
Ongoing
|
2021/01/01 - 2025/12/31 | Center for Innovative Biomedicine and Biotechnology - Associate Laboratory
LA/P/0058/2020
Universidade de Coimbra, Portugal
|
Fundação para a Ciência e a Tecnologia
Ongoing
|
2018/07/06 - 2022/07/05 | LIghtBRARY: A light-activatable nanoparticle library for the delivery of RNA-based therapies
POCI-01-0145-FEDER-029414
Principal investigator
Centro de Inovação em Biomedicina e Biotecnologia (CIBB), Portugal
|
Fundação para a Ciência e a Tecnologia
Concluded
|
2017/01/01 - 2021/06/30 | Tackling Cancer Stem Cells: a challenge and an opportunity to advance in anti-cancer therapy
POCI-01-0145-FEDER-016390
Researcher
Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
Universidade do Porto, Portugal Centro de Inovação em Biomedicina e Biotecnologia (CIBB), Portugal |
Fundação para a Ciência e a Tecnologia
Concluded
|
2015/07/01 - 2020/06 | Enhancing Research in Ageing at the University of Coimbra
eu-repo/grantAgreement/EC/H2020/669088/EU
Post-doc
Universidade de Coimbra Faculdade de Medicina, Portugal
|
European Commission
Concluded
|
2019/01/01 - 2019/12/31 | CNC. IBILI
UID/NEU/04539/2019
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Universidade de Coimbra, Portugal Universidade de Coimbra Instituto de Ciências Nucleares Aplicadas à Saúde, Portugal Universidade de Coimbra Instituto de Investigação Clínica e Biomédica de Coimbra, Portugal |
Fundação para a Ciência e a Tecnologia
Concluded
|
2014 - 2017 | Triggerable nanomaterials to modulate cell activity - NanoTrigger
307384
Post-doc Fellow
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
|
European Research Council
Concluded
|
2014/03/15 - 2016/03/14 | Personalized 3D vascular constructs for toxicity assessment - VASCTOX
PTDC/SAU- TOX/121887/2010
Post-doc Fellow
Biocant Associação de Transferência de Tecnologia, Portugal
Centro de Inovação em Biomedicina e Biotecnologia (CIBB), Portugal |
Fundação para a Ciência e a Tecnologia
Concluded
|
2012/01/01 - 2014/12/31 | Reactivity in colloidal systems derived from supramolecular aggregates
CTQ2011-22436
PhD Student Fellow
Universidade de Santiago de Compostela, Spain
|
Gobierno de España Agencia Estatal de Investigación
Concluded
|
2010/08/10 - 2013/09/30 | Self-assembly of supramolecular aggregates
10PXIB209113PR
PhD Student Fellow
Universidade de Santiago de Compostela, Spain
|
Xunta de Galicia
Concluded
|
Outputs
Publications
Conference abstract |
|
Conference poster |
|
Journal article |
|
Intellectual property
Patent |
|
Activities
Oral presentation
Presentation title | Event name Host (Event location) |
|
---|---|---|
2023/12/07 | Biodegradable anti-senescence nanoparticles | 3rd RESETageing Conference
University of Coimbra (Coimbra, Portugal)
|
2023/09/04 | Engineering nanoparticles for an efficient delivery of senolytics to the aged liver | 33rd Annual Conference of the European Society for Biomaterials
European Society for Biomaterials (Davos, Switzerland)
|
2023/06/29 | Senotherapeutic nanoparticles to target senescent cells in the liver | DGfA Meeting
Leibniz Institute on Aging (Jenna, Germany)
|
2022/10/13 | A nanotechnology-based solution for EPI-ON corneal cross-linking | 23rd European Association for Vision and Eye Research
EVER (Valencia, Spain)
|
2022/01/31 | Light responsive nanoparticles for drug delivery | International Symposium on Emerging Materials for Biomedical Engineering (EMBE2022)
PDPM IIITDM (India)
|
2021/09/07 | Engineering nanoparticles for targeted delivery of RNA-based therapies | 31st Conference of the European Society for Biomaterials (ESB)
European Society for Biomaterials (Porto, Portugal)
|
2021/06/10 | High-throughput screening of nanoparticles to efficiently deliver non-coding RNA | 55th ESCI Annual Scientific Meeting
ESCI (Barcelona, Spain)
|
2020/01/22 | Controlled delivery of siRNA via photodegradable polymeric nanoparticle library | XIII Spanish-Portuguese Conference on Controlled Drug Delivery
Controlled Release Society (Santiago de Compostela, Spain)
|
2019/05/22 | Efficient non-coding RNA delivery in wound healing by photo-triggerable nanoparticles | 53rd Annual Scientific Meeting of the European Society for Clinical Investigation
Universidade de Coimbra (Coimbra, Portugal)
|
2019/03/14 | Advances in Stem Cell Research and Therapeutics: an ethical dilemma? | VII AEICBAS Biomedical Congress
AEICBAS (Porto, Portugal)
|
2017/10/12 | Light-triggerable nanoparticles for the efficient in-vivo non-coding RNA delivery in wound healing | The Portuguese Society for Stem Cells and Cell Therapies (SPCE-TC)
(Lisbon, Portugal)
|
2014/07/22 | Supramolecular systems based on surfactants and p-sulfonatocalix[4]arene | 20th International Symposium on Surfactants in Solution
University of Coimbra (Coimbra, Portugal)
|
2013/06/26 | Micellar shape transition in an imidazolium based-surfactant | 5th Iberian Meeting on Colloids and Interfaces
University of San Sebastian (Donostia-San Sebastian)
|
2012/01/13 | Estudio de ITC de la influencia de la sal en la complejacion de un cation amonio por el p-sulfonatocalix[4]arene. | III Encuentro Gallego de Cinetica y Catalisis
University of Ourense (Ourense, Spain)
|
2011/07/13 | Vesicular aggregates from supramolecular surfactants | 4th Iberian Meeting on Colloids and Interfaces
Faculty of Science - University of Porto (Porto, Portugal)
|
2008/07/13 | Kinetic Study of an Autocatalytic Reaction: Nitrosation of Formamidine Disulfide | XIX IUPAC Conference on Physical Organic Chemistry
University of Santiago de Compostela (Santiago de Compostela, Spain)
|
Supervision
Thesis Title Role |
Degree Subject (Type) Institution / Organization |
|
---|---|---|
2023/10/01 - Current | Development of pharmacological nanoformulations to eliminate senescent cells
Co-supervisor
|
Bioengenharia (Master)
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Universidade do Porto Faculdade de Engenharia, Portugal |
2022/10/01 - Current | Targeted senolytic delivery system to treat liver cirrhosis
Supervisor of João Pedro Oliveira Santos Pitrez
|
Engenharia Química e Biológica (Master)
Instituto Politécnico de Coimbra Instituto Superior de Engenharia de Coimbra, Portugal
|
2022/09/01 - Current | A nanotechnology-based solution for enhancing corneal permeability
Co-supervisor of João Pedro Cidra
|
Ciências de Engenharia Biomédica (Master)
Centro de Inovação em Biomedicina e Biotecnologia (CIBB), Portugal
Universidade de Coimbra, Portugal |
2022/09/01 - Current | Improve corneal permeability in keratoconus treatment: a solution based on nanotechnology
Co-supervisor of Rita Isabel Martins Pais
|
Investigação Biomédica (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal
|
2021/06/01 - Current | Polymeric nanoparticles for gene editing
Co-supervisor
|
PhDExperimental Biology and Biomedicine (PDBEB) (PhD)
Centro de Inovação em Biomedicina e Biotecnologia (CIBB), Portugal
|
2020/11/30 - Current | Reducing senescent cell burden in aging with nanoparticles
Co-supervisor of Andreia Marques
|
Ciências da Saúde (PhD)
Universidade de Coimbra Faculdade de Medicina, Portugal
|
2020/01/01 - Current | A senolytic delivery system able to cross the blood brain barrier
Co-supervisor of Inês Tomé
|
Ciências da Saúde (PhD)
Centro de Inovação em Biomedicina e Biotecnologia (CIBB), Portugal
|
2022/03/01 - 2022/07/21 | Tackling senescence in brain aging
Supervisor of Mauro Henriques
|
Engenharia Biológica (Degree)
Centro de Inovação em Biomedicina e Biotecnologia (CIBB), Portugal
|
2021/01/01 - 2021/12/31 | Light-triggerable delivery of mRNA nanoparticles
Supervisor of Catarina Rebelo
|
Centro de Inovação em Biomedicina e Biotecnologia (CIBB), Portugal
|
2019/09/01 - 2020/12/15 | Development of nanoparticles to target senescent cells
Co-supervisor of Ricardo Casqueiro
|
Investigação Biomédica (Master)
Centro de Inovação em Biomedicina e Biotecnologia (CIBB), Portugal
|
2019/06/01 - 2020/04/30 | mRNA nanoparticles to improve wound healing
Supervisor of Artur Filipe Rodrigues
|
Centro de Inovação em Biomedicina e Biotecnologia (CIBB), Portugal
|
Event organisation
Event name Type of event (Role) |
Institution / Organization | |
---|---|---|
2019/06/28 - 2019/06/29 | Ageing: models, mechanisms and therapies (2019/06/28 - 2019/06/29)
Conference (Member of the Organising Committee)
|
Centro de Inovação em Biomedicina e Biotecnologia (CIBB), Portugal |
2018/06/27 - 2018/06/27 | "Ageing: models and therapies" (2018/06/27 - 2018/06/27)
Workshop
|
Universidade de Coimbra, Portugal |
2018/03/23 - 2018/03/23 | Overcoming Challenges in Scientific Careers, the Biomedical Research Post-Doctoral Forum@UC (2018/03/23 - 2018/03/23)
Symposium (Co-organisor)
|
Centro de Inovação em Biomedicina e Biotecnologia (CIBB), Portugal |
2008/07/13 - 2008/07/18 | XIX IUPAC Conference on Physical Organic Chemistry (2008/07/13 - 2008/07/18)
Conference (Member of the Organising Committee)
|
Universidade de Santiago de Compostela, Spain |
Jury of academic degree
Topic Role |
Candidate name (Type of degree) Institution / Organization |
|
---|---|---|
2023/07/28 | Targeted polymeric nanoparticles for the treatment of fibrosis
(Thesis) Main arguer
|
Rita Durão Rosa Pereira (Master)
Universidade de Coimbra, Portugal
|
2023/03/13 | Evaluation of the presence of nitrosamines in pharmaceuticals (Avaliação da presença de nitrosamines em medicamentos)
(Thesis) Main arguer
|
Filipa Alexandra Duque Fonseca (Master)
Instituto Politécnico de Coimbra Instituto Superior de Engenharia de Coimbra, Portugal
|
2022/07/19 | Development of nanoparticles for delivery of senolytics at the blood-brain barrier
(Thesis) Arguer
|
Mauro Henriques (Other)
Instituto Politécnico de Coimbra Instituto Superior de Engenharia de Coimbra, Portugal
|
2021/07/07 | Evaluation of the effect of NIR radiation on the cornea and retina
(Thesis) Main arguer
|
Jéssica Monteiro (Other)
Universidade de Coimbra, Portugal
|
Association member
Society Organization name | Role | |
---|---|---|
2019/07/21 - Current | Controlled Release Society (CRS) | |
2019/05/22 - Current | European Society for Clinical Investigation (ESCI) | |
2018/09/09 - Current | European Society for Biomaterials (ESB) |
Course / Discipline taught
Academic session | Degree Subject (Type) | Institution / Organization | |
---|---|---|---|
2023/02/21 - Current | Biochemistry and Molecular Biology | Engenharia Biomédica (Licenciatura) | Instituto Politécnico de Coimbra Instituto Superior de Engenharia de Coimbra, Portugal |
2022/09/01 - Current | Cell and Tissue Biology | Engenharia Biomédica (Licenciatura) | Instituto Politécnico de Coimbra Instituto Superior de Engenharia de Coimbra, Portugal |
2018/09/26 - Current | Regenerative Medicine | Engenharia Biomédica (Mestrado) | Universidade de Coimbra Faculdade de Medicina, Portugal |
2018/05/07 - Current | PhD Programme in Experimental Biology and Biomedicine (PDBEB) | Doctoral Program in Experimental Biology and Biomedicine (Doutoramento) | Centro de Inovação em Biomedicina e Biotecnologia (CIBB), Portugal |
Interview (tv / radio show)
Program | Topic | |
---|---|---|
2021/01/13 - Current | 90 segundo de Ciência | Método inovador e sensível à luz para a entrega de moléculas em doenças da pele |
2020/02/18 - 2020/02/18 | Mentes que Brilham |
Journal scientific committee
Journal title (ISSN) | Publisher | |
---|---|---|
2022/09/05 - Current | Frontiers in Biomaterials Science for Regenerative Therapies | Frontiers |
2022/03/25 - Current | Frontiers in Chemistry | |
2020/07/21 - Current | Experimental Results | Cambridge University Press |
Mentoring / Tutoring
Topic | Student name | |
---|---|---|
2021/03/01 - Current | Nanoparticles to target senescent vascular cells | Helena Aires |
2020/10/01 - Current | Synthesis and role of piezoelectric nanoparticles on cardiomyocytes | Luis Monteiro |
2015/01/01 - Current | A light-triggerable nanocarrier library to modulate cell activity | Josephine Blersch |
2021/01/04 - 2021/01/29 | Synthesis and characterisation of an enzyme-responsive delivery system | Jakub Misturik |
2020/06/29 - 2020/07/18 | Senoterapeutic drug delivery systems | Filipe de Campos Hipolito Pedroso Mateus |
2018/03/05 - 2018/10/31 | A light-activatable nanoparticle library for the delivery of RNA-based therapies | Filipe Coelho |
2017/09/01 - 2018/03/31 | Synthesis of light sensitive nanoparticles for drug delivery | Mehrzad Zargarzadeh |
2016/10/01 - 2017/10/31 | Characterisation of a light sensitive nanoparticle library | Malwina Kotowicz |
Distinctions
Award
2023 | Winner of 2nd edition of BiotechSTARS BioBOOST (Bio-entrepreneurship Mentoring Program) - Project NanoLensTech
Biocant Associação de Transferência de Tecnologia, Portugal
|
2022 | Prémio de Investigação Centro Hospitalar e Universitário de Coimbra - Projeto de investigação translacional (Heat-induced
epithelial permeability: A nanoscale-based solution for the treatment of fungal keratitis)
Centro Hospitalar e Universitário de Coimbra EPE, Portugal
|
2020 | Best Poster at XIII Spanish-Portuguese Conference on Controlled Drug Delivery
Spanish Portuguese Local Chapter (SPLC-CRS), Spain
|
Other distinction
2021 | Feature Article - https://doi.org/10.1063/5.0057204
American Institute of Physics (AIP), United States
|
2017 | HOT Article PCCP - https://doi.org/10.1039/C7CP01889D
Royal Society of Chemistry, United Kingdom
|
2014 | Postdoctoral Research Fellowship
Fundação para a Ciência e a Tecnologia, Portugal
|
2008 | PhD Fellowship
Fundação para a Ciência e a Tecnologia, Portugal
|