???global.info.a_carregar???
JOSÉ FILIPE OLIVEIRA DE CASTRO. Completed the Doutoramento in Ciências Biomédicas in 2024/05/07 by Universidade de Lisboa Faculdade de Medicina, Doutoramento in Ciências Biomédicas in 2024/05/07 by Centro Académico de Medicina de Lisboa, Mestrado in Mestrado em Neurociências in 2012 by Universidade de Lisboa Faculdade de Medicina, Licenciatura in Título de Especialista na área de Fisiologia Clínica in 2020/09/14 by Instituto Politécnico de Lisboa Escola Superior de Tecnologia da Saúde de Lisboa and Licenciatura in Neurofisiologia in 2005 by Instituto Politécnico do Porto Escola Superior de Saúde. Is Técnico de Diagnóstico e Terapêutica - Neurofisiologia in Centro Hospitalar Universitário Lisboa Norte EPE, Researcher in Instituto de Medicina Molecular João Lobo Antunes, Invited Assistant in Universidade de Lisboa Faculdade de Medicina and Tutor in Instituto Politécnico de Lisboa Escola Superior de Tecnologia da Saúde de Lisboa. Published 29 articles in journals. Organized 1 event(s). Participates and/or participated as Researcher in 1 project(s). Works in the area(s) of Medical and Health Sciences with emphasis on Clinical Medicine with emphasis on Clinical Neurology and Medical and Health Sciences with emphasis on Basic Medicine with emphasis on Neurosciences. In his curriculum Ciência Vitae the most frequent terms in the context of scientific, technological and artistic-cultural output are: Electromiografia; Estimulação Magnética Transcraniana; Unidades Motoras; Nervo periférico; Doenças neurodegenerativas; Axónio; Amyotrophic lateral sclerosis; Motor neuron disease; interneurons; inhibitory circuits; segmental spinal inhibition; cortical inhibition; Imunologia; Medicina Molecular; Infecção; Neurociências; .
Read full resume ↓
Identification

Personal identification

Full name
JOSÉ FILIPE OLIVEIRA DE CASTRO

Citation names

  • Castro, José

Author identifiers

Ciência ID
7C1E-6635-38C2
ORCID iD
0000-0001-8984-475X

Email addresses

  • jose.zecastro25@gmail.com (Professional)
  • jose.castro@medicina.ulisboa.pt (Professional)

Addresses

  • Hospital Stª Maria. Av. Prof. Egas Moniz, 1600, Lisboa, Lisboa, Portugal (Professional)

Knowledge fields

  • Medical and Health Sciences - Clinical Medicine - Clinical Neurology
  • Medical and Health Sciences - Basic Medicine - Neurosciences

Languages

Language Speaking Reading Writing Listening Peer-review
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Education
Degree Classification
2019/11/01 - 2024/05/07
Concluded
 Ciências Biomédicas (Doutoramento)
Major in Neurociências
Universidade de Lisboa Faculdade de Medicina, Portugal

Centro Académico de Medicina de Lisboa, Portugal
"Inhibitory Circuitry in Motor Neuron Disease: Changes in Spinal and Corticospinal Mechanisms in Amyotrophic Lateral Sclerosis and its Variants" (THESIS/DISSERTATION)
 Aprovado com distinção e louvor
2020/09/14 - 2020/09/14
Concluded
 Título de Especialista na área de Fisiologia Clínica (Licenciatura)
Major in Área de Estudos em Neurofisiologia
Instituto Politécnico de Lisboa Escola Superior de Tecnologia da Saúde de Lisboa, Portugal
 Aprovado
2012
Concluded
 Mestrado em Neurociências (Mestrado)
Universidade de Lisboa Faculdade de Medicina, Portugal
"MUNIX, A new method of motor unit number estimation" (THESIS/DISSERTATION)
 20 valores
2005
Concluded
 Neurofisiologia (Licenciatura)
Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
"n/a" (THESIS/DISSERTATION)
 14 Valores
Affiliation

Science

Category
Host institution 		Employer
2007 - Current Researcher (Research) Instituto de Medicina Molecular João Lobo Antunes, Portugal

Teaching in Higher Education

Category
Host institution 		Employer
2018 - Current Tutor (Polytechnic Teacher) Instituto Politécnico de Lisboa Escola Superior de Tecnologia da Saúde de Lisboa, Portugal
Hospital de Santa Maria, Portugal
2017/12 - Current Invited Assistant (University Teacher) Universidade de Lisboa Faculdade de Medicina, Portugal
2019 - 2020 Invited Assistant (University Teacher) Instituto Politécnico de Lisboa Escola Superior de Tecnologia da Saúde de Lisboa, Portugal
2006 - 2017 Tutor (Polytechnic Teacher) Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
Hospital de Santa Maria, Portugal

Others

Category
Host institution 		Employer
2004/10/01 - Current Técnico de Diagnóstico e Terapêutica - Neurofisiologia Centro Hospitalar Universitário Lisboa Norte EPE, Portugal
Projects

Contract

Designation Funders
2011/01/01 - 2013/02/17 Projecto Estratégico - LA 5 - 2011-2012
PEst-OE/SAU/LA0005/2011
Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded

Other

Designation Funders
2020/01 - 2024/01 Spinal circuitry in Motor Neuron Disease: Changes in Spinal and Corticospinal Mechanisms in Amyotrophic Lateral Sclerosis and its variants
Spinal circuitry in Motor Neuron Disease
Researcher
Universidade de Lisboa Faculdade de Medicina, Portugal
 Biogen Idec Portugal
Concluded
Outputs

Publications

Journal article
  1. Malanda, Armando; Stashuk, Daniel; Valle, César; Rodríguez-Falces, Javier; Navallas, Javier; Carvalho, Mamede; Castro, José; Garnés-Camarena, Oscar. "Automatic Method for Jitter Estimation in Electromyographic Signals". EMJ Neurology (2024): 58-59. https://doi.org/10.33590/emjneurol/kcdw3797.
    10.33590/emjneurol/kcdw3797
  2. José Castro; Miguel Oliveira Santos; Michael Swash; Mamede de Carvalho. "Segmental motor neuron dysfunction in amyotrophic lateral sclerosis: Insights from H reflex paradigms". Muscle & Nerve (2024): https://doi.org/10.1002/mus.28035.
    10.1002/mus.28035
  3. José Castro; Tomás Pedrosa; Inês Alves; Sara Simão; Michael Swash; Mamede de Carvalho. "A neurophysiological approach to mirror movements in amyotrophic lateral sclerosis". Clinical Neurophysiology (2024): https://doi.org/10.1016/j.clinph.2023.12.002.
    10.1016/j.clinph.2023.12.002
  4. Vítor, Joana; Moniz Dionísio, Joana; Campos, Catarina; Oliveira Santos, Miguel; Cruz, Simão; Castelo, Juliana; Castro, José; et al. "The Incidence of Guillain-Barré Syndrome during COVID-19 Pandemic: A Portuguese Multicentric Retrospective Study". Sinapse 23 4 (2024): 182-187. https://doi.org/10.46531/sinapse/ao/230055/2023.
    10.46531/sinapse/ao/230055/2023
  5. José Castro; Michael Swash; Mamede de Carvalho. "The cutaneous silent period as a measure of upper motor neuron dysfunction in amyotrophic lateral sclerosis". Neurophysiologie Clinique (2023): https://doi.org/10.1016/j.neucli.2022.102843.
    10.1016/j.neucli.2022.102843
  6. José Castro; Tomás Pedrosa; Isabel de Castro; Michael Swash; Mamede de Carvalho. "Mirror movements – A simple algorithm for mirror activity signal processing and normative values". Neuroscience Letters (2023): https://doi.org/10.1016/j.neulet.2023.137186.
    10.1016/j.neulet.2023.137186
  7. Isabel Conceição; Isabel de Castro; Andrés Diaz; José Castro. "Quantitative sensory testing: a good tool to identify subclinical neuropathy in ATTRV30M amyloidosis patients?". Amyloid (2022): https://doi.org/10.1080/13506129.2022.2155132.
    10.1080/13506129.2022.2155132
  8. José Castro; Bruno Miranda; Isabel de Castro; Isabel Conceição. "Changes in nerve conduction studies predate clinical symptoms onset in early onset Val30Met hereditary ATTR amyloidosis". European Journal of Neurology (2022): https://doi.org/10.1111/ene.15176.
    10.1111/ene.15176
  9. Chan, Young; Alix, James J. P.; Neuwirth, Christoph; Barkhaus, Paul E.; Castro, José; Jenkins, Thomas M.; McDermott, Christopher J.; et al. "Reinnervation as measured by the motor unit size index is associated with preservation of muscle strength in amyotrophic lateral sclerosis, but not all muscles reinnervate". Muscle & Nerve 65 2 (2021): 203-210. https://doi.org/10.1002/mus.27444.
    10.1002/mus.27444
  10. Oliveira Santos, Miguel; Castro, Isabel; Castro, José; Gromicho, Marta; de Carvalho, Mamede. "Assessment of sympathetic sudomotor function in amyotrophic lateral sclerosis with electrochemical skin conductance". Clinical Neurophysiology 132 9 (2021): 2032-2036. https://doi.org/10.1016/j.clinph.2021.05.016.
    10.1016/j.clinph.2021.05.016
  11. Castro, José; Swash, Michael; de Carvalho, Mamede. "The cutaneous silent period in motor neuron disease". Clinical Neurophysiology 132 2 (2021): 660-665. https://doi.org/10.1016/j.clinph.2020.10.033.
    Published • 10.1016/j.clinph.2020.10.033
  12. Adams, David; Polydefkis, Michael; González-Duarte, Alejandra; Wixner, Jonas; Kristen, Arnt V; Schmidt, Hartmut H; Berk, John L; et al. "Long-term safety and efficacy of patisiran for hereditary transthyretin-mediated amyloidosis with polyneuropathy: 12-month results of an open-label extension study". The Lancet Neurology 20 1 (2021): 49-59. https://doi.org/10.1016/s1474-4422(20)30368-9.
    10.1016/s1474-4422(20)30368-9
  13. Castro, José. "Assessment of the reliability of the motor unit size index (MUSIX) in single subject “round-robin” and multi-centre settings". Clinical Neurophysiology (2019): http://dx.doi.org/10.1016/j.clinph.2019.01.020.
    10.1016/j.clinph.2019.01.020
  14. Catarina Falcão de Campos; Isabel Conceição; Isabel de Castro; José Castro. "Early diagnostic tools in hereditary amyloidosis related to transthyretin (hATTR) V30M autonomic neuropathy". Amyloid 26 sup1 (2019): 35-36. https://doi.org/10.1080/13506129.2019.1582503.
    10.1080/13506129.2019.1582503
  15. Isabel Conceição; Isabel de Castro; José Castro. "Correlation between Sudoscan and COMPASS 31: assessment of autonomic dysfunction on hATTR V30M patients". Amyloid 26 sup1 (2019): 23-23. https://doi.org/10.1080/13506129.2019.1582494.
    10.1080/13506129.2019.1582494
  16. I. Conceição; B. Miranda; J. Castro; M. de Carvalho. "Hereditary amyloidosis related to transthyretin V30M: disease progression in treated and untreated patients". European Journal of Neurology (2018): https://doi.org/10.1111/ene.13724.
    10.1111/ene.13724
  17. José Castro; João Costa; Isabel de Castro; Isabel Conceição. "Electrochemical skin conductance in hereditary amyloidosis related to transthyretin V30M – a promising tool to assess treatment efficacy?". Amyloid 25 4 (2018): 267-268. https://doi.org/10.1080/13506129.2018.1545639.
    10.1080/13506129.2018.1545639
  18. Nascimento Alves, P.; de Carvalho, M.; Reimão, S.; Castro, J.; Fonseca, A.C.; Canhão, P.. "Voluntary control of a plegic limb during yawning". Journal of Neurology 265 2 (2018): 433-435. http://www.scopus.com/inward/record.url?eid=2-s2.0-85040346760&partnerID=MN8TOARS.
    10.1007/s00415-017-8729-z
  19. Falcão de Campos, C.; Viana, P.; de Castro, I.; Castro, J.; de Carvalho, M.; Conceição, I.. "Non-invasive evaluation of sudomotor function in patients with myasthenia gravis". Neurophysiologie Clinique (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85058236130&partnerID=MN8TOARS.
    10.1016/j.neucli.2018.12.002
  20. Neuwirth, C.; Barkhaus, P.E.; Burkhardt, C.; Castro, J.; Czell, D.; de Carvalho, M.; Nandedkar, S.; Stålberg, E.; Weber, M.. "Motor Unit Number Index (MUNIX) detects motor neuron loss in pre-symptomatic muscles in Amyotrophic Lateral Sclerosis". Clinical Neurophysiology 128 3 (2017): 495-500. http://www.scopus.com/inward/record.url?eid=2-s2.0-85009468998&partnerID=MN8TOARS.
    10.1016/j.clinph.2016.11.026
  21. José Castro; Bruno Miranda; Isabel Castro; Mamede de Carvalho; Isabel Conceição. "The diagnostic accuracy of Sudoscan in transthyretin familial amyloid polyneuropathy". Clinical Neurophysiology 127 5 (2016): 2222-2227. https://doi.org/10.1016/j.clinph.2016.02.013.
    10.1016/j.clinph.2016.02.013
  22. Neuwirth, C.; Burkhardt, C.; Alix, J.; Castro, J.; De Carvalho, M.; Gawel, M.; Goedee, S.; et al. "Quality control of Motor Unit Number Index (MUNIX) measurements in 6 muscles in a single-subject "round-robin" setup". PLoS ONE 11 5 (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-84967321300&partnerID=MN8TOARS.
    10.1371/journal.pone.0153948
  23. Neuwirth, C.; Barkhaus, P.E.; Burkhardt, C.; Castro, J.; Czell, D.; De Carvalho, M.; Nandedkar, S.; Stålberg, E.; Weber, M.. "Tracking motor neuron loss in a set of six muscles in amyotrophic lateral sclerosis using the Motor Unit Number Index (MUNIX): A 15-month longitudinal multicentre trial". Journal of Neurology, Neurosurgery and Psychiatry 86 11 (2015): 1172-1179. http://www.scopus.com/inward/record.url?eid=2-s2.0-84942692366&partnerID=MN8TOARS.
    10.1136/jnnp-2015-310509
  24. Conceição I; Costa J; Castro J; de Carvalho M. "Neurophysiological techniques to detect early small-fiber dysfunction in transthyretin amyloid polyneuropathy.". (2013): http://europepmc.org/abstract/med/23681916.
    10.1002/mus.23901
  25. Neuwirth C; Nandedkar S; Stålberg E; Barkhaus PE; Carvalho Md; Furtula J; Dijk JP; et al. "Motor Unit Number Index (MUNIX): a novel neurophysiological marker for neuromuscular disorders; test-retest reliability in healthy volunteers.". (2011): http://europepmc.org/abstract/med/21396884.
    10.1016/j.clinph.2011.02.017
  26. Neuwirth C; Nandedkar S; Stålberg E; Barkhaus PE; Carvalho Md; Furtula J; van Dijk JP; et al. "Motor Unit Number Index (MUNIX): reference values of five different muscles in healthy subjects from a multi-centre study.". (2011): http://europepmc.org/abstract/med/21689981.
    10.1016/j.clinph.2011.05.014
  27. Conceição I; Evangelista T; Castro J; Pereira P; Silvestre A; Coutinho CA; de Carvalho M. "Acquired amyloid neuropathy in a Portuguese patient after domino liver transplantation.". (2010): http://europepmc.org/abstract/med/20928908.
    10.1002/mus.21806
  28. Geraldes R; Coelho M; Rosa MM; Severino L; Castro J; de Carvalho M. "Abnormal transcranial magnetic stimulation in a patient with presumed psychogenic paralysis.". (2008): http://europepmc.org/abstract/med/19010957.
    10.1136/jnnp.2008.154583
  29. Conceição IM; Castro JF; Scotto M; de Carvalho M. "Neurophysiological markers in familial amyloid polyneuropathy patients: early changes.". (2008): http://europepmc.org/abstract/med/18308631.
    10.1016/j.clinph.2008.01.006
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2023 A neurophysiological approach to mirror movements in Amyotrophic Lateral Sclerosis Congresso de Neurologia
Sociedade Portuguesa de Neurologia (Porto, Portugal)
2015 Sudomotor Function Assessed by Sudoscan in TTR-FAP Patients The 15th European Congress on Clinical Neurophysiology
IFCN (Brno, Czech Republic)
2012 Miastenia gravis e neuropatia crónica inflamatória desmielinizante associadas a Doença de Graves Reunião de Outono da SPEDNM
SPEDNM (Aveiro, Portugal)
2011 The Radial to Median Sensory Potential Diference in Carpal Tunnel Syndrome 6th Course of Clinical Neurophysiology
APEEGNC (Carcavelos, Portugal)
2010 Munix – Primeiros resultados XXXV REUNIÃO ANUAL DA APEEGNC
Associação Portuguesa de EEG e Neurofisiologia Clínica (Portimão, Portugal)
2010 Potenciais Evocados a Laser – Estado da Arte II Jornadas de Neurofisiologia da ESTSP-IPP
ESTSP - IPP (Porto, Portugal)
2009 Estimulação magnética transcraniana e paralisia psicogénica Reunião de Primavera da SPEDNM
SPEDNM (Sesimbra, Portugal)
2009 Monitorização Intra-Operatória – Estado da Arte I Jornadas de Neurofisiologia da ESTSP-IPP
ESTSP - IPP (Porto, Portugal)
2008 Neuromiotonia revisitada – Perspectiva evolutiva de um caso clínico; Reunião de Primavera da SPEDNM
SPEDNM (Bussaco, Portugal)
2007 Changes of nerve conduction studies and sympathetic skin responses in assymptomatic and early symptomatic FAP patients 5º Curso de Neurofisiologia Clínica
Associação Portuguesa de EEG e Neurofisiologia Clínica (Carcavelos, Portugal)

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2019/09/09 - 2019/09/13 11th OSET Congress (2019/09/09 - 2019/09/13)
Congress (Member of the Organising Committee)
 Associação Portuguesa de Técnicos de Neurofisiologia, Portugal

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2023/08/22 Low Intensity F-Wave Stimulation As A Marker Of Excitability Of Lower Motor Neurons Innervating Hand Muscles
(Thesis) Main arguer
 Miguel Afonso Neves Lopes (Master)
Universidade de Lisboa Faculdade de Medicina, Portugal
2022/09/20 Desenvolvimento de uma ferramenta para análise de imagens SPECT em pacientes com descargas periódicas em eletroencefalografia
(Thesis) Arguer
 Christianne Gonçalves de Barros Teixeira (Master)
Instituto Politécnico de Lisboa Escola Superior de Tecnologia da Saúde de Lisboa, Portugal
2018/01/09 Lesão da via corticoespinhal e variabilidade no recrutamento de unidades motoras
(Thesis) Main arguer
 Artiom Viatcheslavovitch Poliakov (Master)
Universidade de Lisboa Faculdade de Medicina, Portugal

Association member

Society Organization name Role
2010/06/01 - Current Associação Portuguesa de Técnicos de Neurofisiologia Cargo Diretivo