Fábio Gabriel Rodrigues Teixeira (7D14-5AA0-450A)

Curriculum Vitae

Fábio Gabriel Rodrigues Teixeira

Fábio Teixeira got his Ph.D. in Health Sciences from the Medical School of the University of Minho in 2015 in collaboration with the Pharmaceutical Production Research Facility (PPRF), University of Calgary. In February 2015, he started a post-doc position at ICVS, exploring the impact of regenerative medicine strategies and pharmacological approaches for Parkinson’s Disease (PD) treatment. Currently, as an FCT-CEEC Assistant Researcher at i3S, he has started his own line of research in collaboration with the Center for Translational Health and Medical Biotechnology Research (TBIO), ESS|P. Porto, which is currently focused on two main topics: (1) addressing the role of prodromic phases (e.g., neuropsychiatric conditions such as depression) in the deterioration of PD, and how they can influence the onset and progression of its pathophysiology, and (2) testing/developing/repurposing disease-modifying strategies to intervene in PD progression, focusing on neuron-glia crosstalk and cellular|molecular (neuroinflammation, autophagy, and oxidative stress), and metabolic changes that can occur in pre-clinical models and even in clinical samples. In collaboration with TBIO, ESS|P. Porto, his team is also involved in the effort to understand the relation between the intestinal microflora and the brain (referred to as the “microbiota-gut-brain axis”), and its role in the development of neurodegenerative disorders, specifically PD. The expectation is to comprehend if the gut microbiome might be a main player (or even a therapeutic target) in a diseased context and to determine its influence on survival, disease progression, and neurochemical dysfunctions. He is currently an author of 44 scientific publications, cited over 2000 citations (Scopus h-index=25). He has received several distinctions, denoting the 'Mantero Belard Neuroscience Prize', the most important prize in the field of neurodegenerative diseases research in Portugal. He presents a good track record that is recognized for his work in nervous system modulation, including the design and assessment of in vitro and in vivo disease-modifying strategies to underly and treat PD.

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Identification

Personal identification

Full name: Fábio Gabriel Rodrigues Teixeira

Citation names

Teixeira, Fábio G

Author identifiers

Ciência ID: 7D14-5AA0-450A
ORCID iD: 0000-0003-1461-9077
Researcher Id: F-8204-2012
Scopus Author Id: 49664121700

Email addresses

fteixeira@i3s.up.pt (Professional)

Addresses

Rua Alfredo Allen, 208, 4200-135, Porto, Porto, Portugal (Professional)

Knowledge fields

Medical and Health Sciences - Medical Biotechnology - Technologies Involving the Manipulation of Cells, Tissues, Organs or the Whole Organism
Medical and Health Sciences - Basic Medicine - Pharmacology and pharmacy
Medical and Health Sciences - Medical Biotechnology - Health-Related Biotechnology
Medical and Health Sciences - Basic Medicine - Neurosciences

Languages

Language	Speaking	Reading	Writing	Listening	Peer-review
Portuguese (Mother tongue)
English	Advanced (C1)	Advanced (C1)	Advanced (C1)	Advanced (C1)	Advanced (C1)
French	Intermediate (B1)	Intermediate (B1)	Beginner (A1)	Intermediate (B1)	Intermediate (B1)

Education

	Degree	Classification
2015/02/01 - 2019/07/14 Concluded	Health Sciences (Pós-doutoramento) Laboratório Associado ICVS 3B's, Portugal Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal Universidade do Minho Escola de Medicina, Portugal
2015/01/30 Concluded	PhD in Health Sciences (Doutoramento) Major in Health Sciences Universidade do Minho Escola de Medicina, Portugal Laboratório Associado ICVS 3B's, Portugal Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal "Modulation of the Secretome of Mesenchymal Stem Cells for Central Nervous System Regenerative Medicine Applications" (THESIS/DISSERTATION)
2008/09/22 - 2010/11/29 Concluded	Oncology (Mestrado) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal "Effects of human umbilical cord perivascular stem cells and their conditioned media on the dentate gyrus of hippocampus" (THESIS/DISSERTATION)
2005/09/19 - 2008/07/31 Concluded	Applied Biology (Licenciatura) Major in Oncobiologia Universidade do Minho Escola de Ciências, Portugal "Valences of Immunohistochemistry" (THESIS/DISSERTATION)

Affiliation

Science

	Category Host institution	Employer
2022/08/01 - Current	Auxiliary Researcher (Research)	Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

2022/01/02 - 2022/07/31	Auxiliary Researcher (Research)	Instituto Politécnico do Porto, Portugal

2019/07/15 - 2021/10/31	Auxiliary Researcher (Research)	Laboratório Associado ICVS 3B's, Portugal
	Universidade do Minho Escola de Medicina, Portugal
2015/02/01 - 2019/07/14	Postdoc (Research)	Laboratório Associado ICVS 3B's, Portugal
	Universidade do Minho Escola de Medicina, Portugal

Teaching in Higher Education

	Category Host institution	Employer
2023/02 - Current	Invited Adjunct Teacher (Polytechnic Teacher)	Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
	Instituto Politécnico do Porto Escola Superior de Saúde, Portugal

Others

	Category Host institution	Employer
2023/11 - Current	TBIO Molecular Biology Lab Coordinator	Instituto Politécnico do Porto Escola Superior de Saúde, Portugal

2022/09 - Current	Team leader of the 'Experimental Neurodegeneration Biology' Research Line	Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
	Instituto Politécnico do Porto Escola Superior de Saúde, Portugal (...)
2021/05/21 - 2021/05/26	Visiting Scientist	Frédéric Joliot Institute for Life Sciences - NeuroSpin, France

2010/09/27 - 2015/01/30	PhD student in Health Sciences	Laboratório Associado ICVS 3B's, Portugal
	Universidade do Minho Escola de Medicina, Portugal
2014 - 2014	Member of the Pedagogic Council	Universidade do Minho Escola de Medicina, Portugal

2012/05/20 - 2013/06/12	Visiting Scientist	Pharmaceutical Production Research Facility (PPRF), Canada

2008/09/22 - 2010/11/29	MSc student in Oncology	Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

2008/03/01 - 2008/07/31	Research Trainee	Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Projects

Grant

	Designation	Funders
2025/01/01 - Current	Oxy4PD: Will Oxygen along with multimodal antidepressants be a path to mitigate Parkinson’s Disease progression and deterioration? 2023.14158.PEX Principal investigator	Fundação para a Ciência e a Tecnologia
2022/08 - 2028	DrivePD: Targeting Parkinson Disease Brain affected areas with Multimodal Regenerative Strategies by Blood-Brain Barrier transient openings 2021.00643.CEECIND 2021.00643.CEECIND Principal investigator Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2023/01/01 - 2025/12/31	Hippocampal connectivity and behavioral performance in health and depression: where does adult astrogliogenesis stand? 2022.02201.PTDC Researcher Laboratório Associado ICVS 3B's, Portugal Universidade do Minho, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2023/01/01 - 2024/07/31	Use of Aptamers Towards Theranostics and Precision Medicine in Prostate Carcinoma 2022.09032.PTDC Researcher	Fundação para a Ciência e a Tecnologia Ongoing
2020/01/02 - 2024/06/30	SynChronize: Focused Ultrasound combined with Stem Cells Secretome and Pharmacotherapies: establishing a Multimodal path for Parkinson?s Disease repair SCML-MB-28-2019 Principal investigator Universidade do Minho Escola de Medicina, Portugal Laboratório Associado ICVS 3B's, Portugal Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal	Santa Casa da Misericórdia de Lisboa Ongoing
2020 - 2023	Diamond4Brain - Diamond Photonics Platforms for Synaptic Connectivity Assessment in Healthy and Parkinson Disease Neuronal Models HR-00249 Researcher Laboratório Associado ICVS 3B's, Portugal Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal International Iberian Nanotechnology Laboratory, Portugal Universidade de Aveiro Instituto de Biomedicina, Portugal	Concluded
2018/07/01 - 2021/12/31	Combining Mesenchymal Stem Cells (MSCs) Secretome and Pharmacotherapies for the treatment of Parkinson’s Disease POCI-01-0145-FEDER-029751 SFRH/BPD/118408/2016 Principal investigator Laboratório Associado ICVS 3B's, Portugal Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2016 - 2019	Targeting Spinal Cord Injury Repair trough Nanoporous Biodegradable 3D Matrices TUBITAK/0007/2014 Researcher Laboratório Associado ICVS 3B's, Portugal Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2017 - 2018	Testing the therapeutic potential of mesenchymal stem cells and their secretome in an animal model of spinocerebellar ataxia type 3 N/A Researcher Laboratório Associado ICVS 3B's, Portugal Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal	National Ataxia Foundation Concluded
2017 - 2018	On-chip selection of exosomal vectors for Parkinson’s disease treatment N/A Principal investigator Laboratório Associado ICVS 3B's, Portugal Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal International Iberian Nanotechnology Laboratory, Portugal	Laboratório Associado ICVS 3B's Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde International Iberian Nanotechnology Laboratory Concluded
2013 - 2016	Development of an Integrative Therapy for Spinal Cord Injury Regeneration based on Inductive Biodegradable Biomaterials, Mesenchymal Stem Cells and Neuro-Protective Agents MC017/13 Researcher Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal Laboratório Associado ICVS 3B's, Portugal	Santa Casa da Misericórdia de Lisboa Concluded
2010/11/01 - 2014/10/31	MODULATION OF THE SECRETOME OF MESENCHYMAL STEM CELLS FOR CENTRAL NERVOUS SYSTEM REGENERATIVE MEDICINE APPLICATIONS SFRH/BD/69637/2010	Fundação para a Ciência e a Tecnologia Concluded
2008 - 2010	Identification of key neuroregulatory molecules expressed by Human umbilical cord stem cells N/A Researcher Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal Laboratório Associado ICVS 3B's, Portugal	Fundação Calouste Gulbenkian Concluded

Contract

	Designation	Funders
2018/08/10 - 2022/08/08	Development of an autologous exosome-based therapy by engineering microRNAs in microglia and motor-neurons using mice and human models of amyotrophic lateral sclerosis (ALS) PTDC/MED-NEU/31395/2017 Universidade do Minho, Portugal Instituto Politécnico de Coimbra Centro de Estudos de Recursos Naturais Ambiente e Sociedade, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2019/01/01 - 2019/12/31	ICVS/3B¿s - Associate Laboratory, Life and Health Sciences Research Institute / Biomaterials, Biodegradables and Biomimetics Research Group UID/Multi/50026/2019 Universidade do Minho, Portugal Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2016/07/01 - 2019/11/30	Farmacologia e Células Estaminais para Reparar as Lesões da Medula Espinhal: Será o Todo Maior que a Soma das suas Partes? PTDC/DTP-FTO/5109/2014 Universidade do Minho, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2013/05/01 - 2015/09/30	DJ-1 neuronal rescue under oxidative stress: implications for Parkinson's disease PTDC/NEU-NMC/0205/2012 Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal Universidade do Minho, Portugal Universidade da Beira Interior, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2011/01/01 - 2012/12/31	Strategic Project - LA 26 - 2011-2012 PEst-C/SAU/LA0026/2011 Universidade do Minho, Portugal	Fundação para a Ciência e a Tecnologia Concluded

Outputs

Publications

Book chapter	Araújo, Bruna; Silva, Rita Caridade; Domingues, Sofia; Salgado, António J.; Teixeira, Fábio G.. "Mesenchymal Stem Cell Secretome: A Potential Biopharmaceutical Component to Regenerative Medicine?". In Handbook of Stem Cell Therapy, 1-33. Springer Nature Singapore, 2022. 10.1007/978-981-16-6016-0_46-1 Mendes-Pinheiro, Bárbara; Marote, Ana; Marques, Cláudia R.; Teixeira, Fábio G.; Ribeiro, Jorge Cibrão; Salgado, António J.. "Applications of the stem cell secretome in regenerative medicine". In Mesenchymal Stem Cells in Human Health and Diseases, 79-114. Elsevier, 2020. 10.1016/b978-0-12-819713-4.00005-0 Teixeira, F.G.; Pires, A.; Serra, S.C.; Sousa, N.; Salgado, A.J.. "The evolving concept of mesenchymal stromal cells in regenerative medicine". In The Biology and Therapeutic Application of Mesenchymal Cells, 222-235. John Wiley & Sons, Inc., 2016. 10.1002/9781118907474.ch18 Teixeira, F. G.; Serra, S. C.; Salgado, A. J.. "Tips on How to Collect and Administer the Mesenchymal Stem Cell Secretome for Central Nervous System Applications". In Methods in Molecular Biology, 457-465. Springer New York, 2016. 10.1007/978-1-4939-3584-0_27
Conference abstract	Caridade-Silva, Rita; Araújo, Bruna; Campos, Jonas; Domingues, Helena S.; Salgado, António José; Teixeira, Fábio G. "N-acetylcysteine as a Parkinson's disease therapy: creating a strategy for disease modeling and repair". Paper presented in International conference on Alzheimer's and Parkinson's Disease and related neurological disorders, Barcelona, 2022. Teixeira, Fábio G. "Finding new secretomes for Parkinson’s Disease regenerative medicine applications". Paper presented in European Neuropsychopharmacology, 2019. Published Teixeira, Fábio G. "Mesenchymal stem cells secretome: a new therapeutic tool for Parkinson’s disease regenerative medicine?". Paper presented in European Neuropsychopharmacology, 2019. Published Teixeira, Fábio G; Teixeira, Fábio G; Carvalho, M.M.; Serra, S.C.; Panchalingam, K.M.; Anjo, S.I.; Manadas, B.; et al. "Mesenchymal Stem Cells Secretome as Modulator of Brain Repair: Effects on Neurogenesis and Parkinson’s Disease Regeneration". Paper presented in TERMIS, 2015. Published Teixeira, Fábio G. "Functional gellan gum hydrogels and cell based therapies - A novel therapeutic approach for spinal cord injury regeneration". Paper presented in TERMIS, 2014. Published Teixeira, Fábio G. "Using the secretome of mesenchymal stem cells progenitors of the umbilical cord as a modulator of neural and glial survival, viability and differentiation". Paper presented in TERMIS, 2012. Published
Conference poster	Vilela, Cristiana; Caridade-Silva, Rita; Araújo, Bruna; Soares-Guedes, Carla; Teixeira, Catarina; Gomes, Eduardo D.; Vieira, Mónica; Teixeira, Fábio G. Corresponding author: Teixeira, Fábio G. "N-acetylcysteine as a modulator of Microbiome levels: A New Aproach For Parkinson’s Disease Treatment?". Paper presented in Encontro Ciência 2024 - Encontro com a Ciência e a Tecnologia, 2024. Caridade-Silva, Rita; Araújo, Bruna; Vilaça- Ferreira, AC.; Fernandes, Hugo; Wade-Martins, Richard; Teixeira, Fábio G. "Multi-targeted strategies to arrest Parkinson’s Disease: the utility of repurposing drugs for neuroprotective approaches". Paper presented in International conference on Alzheimer's and Parkinson's Disease and related neurological disorders (2024), 2024. Caridade-Silva, Rita; Araújo, Bruna; Hugo JR Fernandes; Wade-Martins, Richard; Teixeira, Fábio G. "Repurposing Multimodal Strategies for Parkinson¿s Disease: Creating the Path for Disease Delay and Repair?". Paper presented in Brilliant PhDs, brighter future: Shaping Science together! (PhDay 2023), 2023. Teixeira, Catarina; Falcão-Pires, Inês; Inês Alencastre; Teixeira, Fábio G. "Repurposing Felodipine as a modulator of the Brain-Heart-Kidney axis". 2023. Bruna Araújo; Jonas Campos; Rita Caridade Silva; Bárbara-Mendes Pinheiro; Raquel Marques; Sandra Barata; Rui Lima; et al. Corresponding author: Fábio G. Teixeira. "Modulation of Brain Connectivity, Structure, and Motor Function by Safinamide Multimodal Actions in a Pre-clinical Model of Parkinson’s Disease.". Paper presented in 11th IBRO World Congress Neuroscience, 2023. Rita Caridade-Silva; Bruna Araújo; Joana Martins-Macedo; Benoit Larrat; Sébastien Mériaux; Fábio G Teixeira. Corresponding author: Fábio G Teixeira. "Impact of N-acetylcysteine on Parkinson’s Disease Functional Connectomics: a Friend or Foe?". Paper presented in 11th IBRO World Congress Neuroscience, 2023. Bruna Araújo; Jonas Campos; Rita Caridade Silva; Helena S. Domingues; Bárbara Mendes-Pinheiro; Raquel Marques; Sandra Barata; et al. Corresponding author: Fábio G. Teixeira. "Addressing the Impact of Safinamide as a Parkinson’s Disease Neuroprotective Drug.". Paper presented in AD/PD 2022 ADVANCES IN SCIENCE & THERAPY. International Conference on Alzheimer’s and Parkinson’s Diseases and related neurological disorders., 2022. Rita Caridade Silva; Bruna Araújo; Jonas Campos; Helena S. Domingues; António J. Salgado; Fábio G. Teixeira; Caridade-Silva, Rita; et al. "Combining Stem Cells Secretome and N-acetylcysteine to Parkinson¿s Disease Modeling and Repair (Poster Presentation Awarded)". Paper presented in European Neuroscience Conference by Doctoral Students (ENCODS), 2021. Bruna Araújo; Rita C. Silva; Ricardo Magalhães; Benoit Larrat; Sebastien Mériaux; Ana Pego; Fábio G Teixeira. "Targeting Parkinson’s Disease Brain Affected Areas by the Local Delivery of Multimodal Pharmacological Strategies". Paper presented in European Neuroscience Conference by Doctoral Students (ENCODS), 2021. Teixeira, Fábio G. "Mesenchymal Stem Cells Secretome-Derived Exosomes: Biological Nanovesicles for the Treatment of Parkinson’s Disease?". Paper presented in XVI Meeting of the Portuguese Society for Neurosciences (SPN), 2019. Teixeira, Fábio G; M.M. Carvalho; Panchalingam, K.M.; Jung S.; N. Sousa; Behie, L.A.; A.J. Salgado; Teixeira, Fábio G. "Secretome of Mesenchymal Stem Cells as a New Tool for Central Nervous System Regenerative Medicine". Paper presented in TERMIS-EU 2014, 2014. Gomes, E.D.; Assunção-Silva, R.; Carvalho, M.M.; Teixeira, F.G.; Leite-Almeida, H.; Gimble, J.M.; Sousa, N.; Salgado, A.J.. "Bioengineered Hydrogels and Cell based Therapies - A Novel Therapeutic Approach for Spinal Cord Injury Regeneration". Paper presented in 2nd International Spinal Cord Injury and Neurotrauma Summer School, 2014. Teixeira, Fábio G; J.S. Fraga; M.M. Carvalho; A. Neves-Carvalho; N.A. Silva; F. Marques; S.D. Mesquita; et al. "Secretome of Mesenchymal Progenitors of the Umbilical Cord: A Modulator of Neuronal and Glial Survival and Differentiation?". Paper presented in FENS, 2012. Teixeira, Fábio G; M.M. Carvalho; A. Neves-Carvalho; N.A. Silva; F. Marques; S.D. Mesquita; L. Pinto; N. Sousa; A.J. Salgado. "Human Umbilical Cord (HUCPVCs) Conditioned Media: a mediator for neural/glial cells survival and differentiation?". Paper presented in Society for Neuroscience, 2012. A.O. Pires; A. Neves-Carvalho; M.M. Carvalho; Fábio G. Teixeira; N. Sousa; A.J. Salgado. "Effects of Mesenchymal Stem Cells Secretome in Different Neuronal populations". Paper presented in Society For Neuroscience, 2012. J.S. Fraga, N. Silva, F.G. Teixeira, N.M. Neves, L. Pinto, R.L. Reis, N. Sousa, A.J. Salgado; N. Silva; F.G. Teixeira; N.M. Neves; L. Pinto; R.L. Reis; N. Sousa; A.J. Salgado. "Secretome of Mesenchymal Progenitors from the Umbilical Cord Modulates Cell Densities, Viability and Proliferation in Hippocampal, Cortical and Cerebellar Neuronal Cultures". Paper presented in 5th Annual meeting of the SPCE-TC, 2010.
Journal article	Joana Macedo; Bruna Araujo; Sandra Anjo; Tiago Silveira Rosa; Patrícia Patrício; Nuno Alves; Joana Silva; et al. "Glial-Restricted Precursors stimulate endogenous cytogenesis and effectively recover emotional deficits in a model of cytogenesis ablation". Molecular Psychiatry (2024): https://www.researchsquare.com/article/rs-2747462/v1). Accepted Vilela, Cristiana; Araújo, Bruna; Soares-Guedes, Carla; Caridade-Silva, Rita; Martins-Macedo, J; Teixeira, Catarina; Gomes, Eduardo D.; et al. Corresponding author: Teixeira, Fábio G. "From the Gut to the Brain: Is microbiome a new paradigm in Parkinson’s Disease Treatment?". Cells 13 9 (2024): 770. http://dx.doi.org/10.3390/cells13090770. Accepted • 10.3390/cells13090770 Rita Caridade-Silva; Bruna Araújo; Joana Martins-Macedo; Fábio G. Teixeira. "N-Acetylcysteine Treatment May Compensate Motor Impairments through Dopaminergic Transmission Modulation in a Striatal 6-Hydroxydopamine Parkinson’s Disease Rat Model". Antioxidants (2023): https://doi.org/10.3390/antiox12061257. 10.3390/antiox12061257 Almeida, Cátia; Oliveira, Rita; Baylina, Pilar; Fernandes, Rúben; Teixeira, Fábio G.; Barata, Pedro. "Current Trends and Challenges of Fecal Microbiota Transplantation—An Easy Method That Works for All?". Biomedicines 10 11 (2022): 2742. http://dx.doi.org/10.3390/biomedicines10112742. 10.3390/biomedicines10112742 Araújo, Bruna; Caridade-Silva, Rita; Soares-Guedes, Carla; Martins-Macedo, Joana; Gomes, Eduardo D.; Monteiro, Susana; Teixeira, Fábio G.. "Neuroinflammation and Parkinson’s Disease—From Neurodegeneration to Therapeutic Opportunities". Cells 11 18 (2022): 2908. http://dx.doi.org/10.3390/cells11182908. 10.3390/cells11182908 Fernandes, Júlio Belo; Teixeira, Fábio; Godinho, Catarina. "Personalized Care and Treatment Compliance in Chronic Conditions". Journal of Personalized Medicine 12 5 (2022): 737. http://dx.doi.org/10.3390/jpm12050737. 10.3390/jpm12050737 Pinho, Andreia G.; Cibrão, Jorge R.; Lima, Rui; Gomes, Eduardo D.; Serra, Sofia C.; Lentilhas-Graça, José; Ribeiro, C.; et al. "Immunomodulatory and regenerative effects of the full and fractioned adipose tissue derived stem cells secretome in spinal cord injury". Experimental Neurology 351 (2022): 113989. http://dx.doi.org/10.1016/j.expneurol.2022.113989. 10.1016/j.expneurol.2022.113989 Silva, RitaCaridade; Domingues, HelenaSofia; Salgado, AntónioJ; Teixeira, FábioG. Corresponding author: Teixeira, FábioG. "From regenerative strategies to pharmacological approaches: can we fine-tune treatment for Parkinson’s disease?". Neural Regeneration Research 17 5 (2022): 933. http://dx.doi.org/10.4103/1673-5374.324827. 10.4103/1673-5374.324827 Joana Sofia Correia; Andreia Neves-Carvalho; Bárbara Mendes-Pinheiro; Joel Pires; Fábio Gabriel Teixeira; Rui Lima; Susana Monteiro; et al. "Preclinical Assessment of Mesenchymal-Stem-Cell-Based Therapies in Spinocerebellar Ataxia Type 3". Biomedicines (2021): https://doi.org/10.3390/biomedicines9121754. 10.3390/biomedicines9121754 Vilaça-Faria, Helena; Marote, Ana; Lages, Inês; Ribeiro, Clarisse; Mendes-Pinheiro, Bárbara; Domingues, Ana Verónica; Campos, Jonas; et al. "Fractionating stem cells secretome for Parkinson's disease modeling: Is it the whole better than the sum of its parts?". Biochimie 189 (2021): 87-98. http://dx.doi.org/10.1016/j.biochi.2021.06.008. 10.1016/j.biochi.2021.06.008 Marques, Cláudia R.; Pereira-Sousa, Joana; Teixeira, Fábio G.; Sousa, Rui A.; Teixeira-Castro, Andreia; Salgado, António J.. "Mesenchymal stem cell secretome protects against alpha-synuclein-induced neurodegeneration in a Caenorhabditis elegans model of Parkinson's disease". Cytotherapy (2021): http://dx.doi.org/10.1016/j.jcyt.2021.04.002. 10.1016/j.jcyt.2021.04.002 Domingues, Ana V.; Pereira, Inês M.; Vilaça-Faria, Helena; Salgado, António J.; Rodrigues, Ana J.; Teixeira, Fábio G.. "Glial cells in Parkinson´s disease: protective or deleterious?". Cellular and Molecular Life Sciences (2020): http://dx.doi.org/10.1007/s00018-020-03584-x. 10.1007/s00018-020-03584-x Domingues, Helena S.; Falcão, Ana Mendanha; Mendes-Pinto, Inês; Salgado, António J.; Teixeira, Fábio G.. "Exosome Circuitry During (De)(Re)Myelination of the Central Nervous System". Frontiers in Cell and Developmental Biology 8 (2020): http://dx.doi.org/10.3389/fcell.2020.00483. 10.3389/fcell.2020.00483 Sandra Barata-Antunes; Fábio Teixeira; Bárbara Mendes-Pinheiro; Ana V. Domingues; Helena Vilaça-Faria; Ana Marote; Deolinda Silva; Rui A. Sousa; António J. Salgado. "Impact of Aging on the 6-OHDA-Induced Rat Model of Parkinson’s Disease". International Journal of Molecular Sciences (2020): https://www.mdpi.com/1422-0067/21/10/3459. 10.3390/ijms21103459 Campos, Jonas; Guerra-Gomes, Sónia; Serra, Sofia C.; Baltazar, Graça; Oliveira, João F.; Teixeira, Fábio G.; Salgado, António J.. "Astrocyte signaling impacts the effects of human bone marrow mesenchymal stem cells secretome application into the hippocampus: A proliferation and morphometrical analysis on astrocytic cell populations". Brain Research 1732 (2020): 146700. http://dx.doi.org/10.1016/j.brainres.2020.146700. 10.1016/j.brainres.2020.146700 Cunha, A.M.; Teixeira, F.G.; Guimarães, M.R.; Esteves, M.; Pereira-Mendes, J.; Soares, A.R.; Almeida, A.; et al. "Unilateral accumbal dopamine depletion affects decision-making in a side-specific manner". Experimental Neurology (2020): 113221. http://dx.doi.org/10.1016/j.expneurol.2020.113221. 10.1016/j.expneurol.2020.113221 Teixeira; Vilaça-Faria; Domingues; Campos; Salgado. "Preclinical Comparison of Stem Cells Secretome and Levodopa Application in a 6-Hydroxydopamine Rat Model of Parkinson’s Disease". Cells 9 2 (2020): 315. http://dx.doi.org/10.3390/cells9020315. 10.3390/cells9020315 Teixeira, FábioG; Salgado, AntónioJ. "Mesenchymal stem cells secretome: current trends and future challenges". Neural Regeneration Research 15 1 (2020): 75. http://dx.doi.org/10.4103/1673-5374.264455. 10.4103/1673-5374.264455 Mendes-Pinheiro, Bárbara; Anjo, Sandra I.; Manadas, Bruno; Da Silva, Jorge D.; Marote, Ana; Behie, Leo A.; Teixeira, Fábio G.; Salgado, António J.. "Bone Marrow Mesenchymal Stem Cells' Secretome Exerts Neuroprotective Effects in a Parkinson's Disease Rat Model". Frontiers in Bioengineering and Biotechnology 7 (2019): http://dx.doi.org/10.3389/fbioe.2019.00294. 10.3389/fbioe.2019.00294 Vilaça-Faria, Helena; Salgado, António J.; Teixeira, Fábio G.. "Mesenchymal Stem Cells-derived Exosomes: A New Possible Therapeutic Strategy for Parkinson’s Disease?". Cells 8 2 (2019): 118. http://dx.doi.org/10.3390/cells8020118. 10.3390/cells8020118 Serra, Sofia C.; Costa, João C.; Assunção-Silva, Rita C.; Teixeira, Fábio G.; Silva, Nuno A.; Anjo, Sandro I.; Manadas, Bruno; et al. "Influence of passage number on the impact of the secretome of adipose tissue stem cells on neural survival, neurodifferentiation and axonal growth". Biochimie 155 (2018): 119-128. http://dx.doi.org/10.1016/j.biochi.2018.09.012. 10.1016/j.biochi.2018.09.012 Assunção-Silva, Rita Catarina; Mendes-Pinheiro, Bárbara; Patrício, Patrícia; Behie, Leo A.; Teixeira, Fábio Gabriel; Pinto, Luísa; Salgado, António José. "Exploiting the impact of the secretome of MSCs isolated from different tissue sources on neuronal differentiation and axonal growth". Biochimie 155 (2018): 83-91. http://dx.doi.org/10.1016/j.biochi.2018.07.026. 10.1016/j.biochi.2018.07.026 Marques, Cláudia R.; Marote, Ana; Mendes-Pinheiro, Bárbara; Teixeira, Fábio G.; Salgado, António J.. "Cell secretome based approaches in Parkinson’s disease regenerative medicine". Expert Opinion on Biological Therapy 18 12 (2018): 1235-1245. http://dx.doi.org/10.1080/14712598.2018.1546840. 10.1080/14712598.2018.1546840 Mendes-Pinheiro, Bárbara; Teixeira, Fábio G.; Anjo, Sandra I.; Manadas, Bruno; Behie, Leo A.; Salgado, António J.. "Secretome of Undifferentiated Neural Progenitor Cells Induces Histological and Motor Improvements in a Rat Model of Parkinson's Disease". STEM CELLS Translational Medicine 7 11 (2018): 829-838. http://dx.doi.org/10.1002/sctm.18-0009. 10.1002/sctm.18-0009 Teixeira, Fábio G.; Gago, Miguel F.; Marques, Paulo; Moreira, Pedro Silva; Magalhães, Ricardo; Sousa, Nuno; Salgado, António J.. "Safinamide: a new hope for Parkinson’s disease?". Drug Discovery Today 23 3 (2018): 736-744. http://dx.doi.org/10.1016/j.drudis.2018.01.033. 10.1016/j.drudis.2018.01.033 Gomes, Eduardo D.; Mendes, Sofia S.; Assunção-Silva, Rita C.; Teixeira, Fábio G.; Pires, Ana O.; Anjo, Sandra I.; Manadas, Bruno; et al. "Co-Transplantation of Adipose Tissue-Derived Stromal Cells and Olfactory Ensheathing Cells for Spinal Cord Injury Repair". STEM CELLS 36 5 (2018): 696-708. http://dx.doi.org/10.1002/stem.2785. 10.1002/stem.2785 Lima, Rui; Monteiro, Susana; Lopes, José; Barradas, Pedro; Vasconcelos, Natália; Gomes, Eduardo; Assunção-Silva, Rita; et al. "Systemic Interleukin-4 Administration after Spinal Cord Injury Modulates Inflammation and Promotes Neuroprotection". Pharmaceuticals 10 4 (2017): 83. http://dx.doi.org/10.3390/ph10040083. 10.3390/ph10040083 Sevivas, Nuno; Teixeira, Fábio Gabriel; Portugal, Raquel; Direito-Santos, Bruno; Espregueira-Mendes, João; Oliveira, Filipe J.; Silva, Rui F.; et al. "Mesenchymal Stem Cell Secretome Improves Tendon Cell Viability In Vitro and Tendon-Bone Healing In Vivo When a Tissue Engineering Strategy Is Used in a Rat Model of Chronic Massive Rotator Cuff Tear". The American Journal of Sports Medicine 46 2 (2017): 449-459. http://dx.doi.org/10.1177/0363546517735850. 10.1177/0363546517735850 Pires, Ana O.; Teixeira, F.G.; Mendes-Pinheiro, B.; Serra, Sofia C.; Sousa, Nuno; Salgado, António J.. "Old and new challenges in Parkinson's disease therapeutics". Progress in Neurobiology 156 (2017): 69-89. http://dx.doi.org/10.1016/j.pneurobio.2017.04.006. 10.1016/j.pneurobio.2017.04.006 Oliveira, E.; Assunção-Silva, R. C.; Ziv-Polat, O.; Gomes, E. D.; Teixeira, F. G.; Silva, N. A.; Shahar, A.; Salgado, A. J.. "Influence of Different ECM-Like Hydrogels on Neurite Outgrowth Induced by Adipose Tissue-Derived Stem Cells". Stem Cells International 2017 (2017): 1-10. http://dx.doi.org/10.1155/2017/6319129. 10.1155/2017/6319129 Martins, L.F.; Costa, R.O.; Pedro, J.R.; Aguiar, P.; Serra, S.C.; Teixeira, F.G.; Sousa, N.; et al. "Mesenchymal stem cells secretome-induced axonal outgrowth is mediated by BDNF". Scientific Reports 7 1 (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85021292472&partnerID=MN8TOARS. 10.1038/s41598-017-03592-1 Teixeira, Fábio G. "Impact of the Secretome of Human Mesenchymal Stem Cells on Brain Structure and Animal Behavior in a Rat Model of Parkinson’s Disease". Stem Cells Translational Medicine (2016): http://stemcellstm.alphamedpress.org/content/early/2016/09/22/sctm.2016-0071.abstract. doi: 10.5966/sctm.2016-0071 Teixeira, Fábio G.; Vasconcelos, Natália L.; Gomes, Eduardo D.; Marques, Fernanda; Sousa, João C.; Sousa, Nuno; Silva, Nuno A.; et al. "Bioengineered cell culture systems of central nervous system injury and disease". Drug Discovery Today 21 9 (2016): 1456-1463. http://dx.doi.org/10.1016/j.drudis.2016.04.020. 10.1016/j.drudis.2016.04.020 Sevivas, Nuno; Teixeira, Fábio Gabriel; Portugal, Raquel; Araújo, Luís; Carriço, Luís Filipe; Ferreira, Nuno; Vieira da Silva, Manuel; et al. "Mesenchymal Stem Cell Secretome: A Potential Tool for the Prevention of Muscle Degenerative Changes Associated With Chronic Rotator Cuff Tears". The American Journal of Sports Medicine 45 1 (2016): 179-188. http://dx.doi.org/10.1177/0363546516657827. 10.1177/0363546516657827 Marote, Ana; Teixeira, Fábio G.; Mendes-Pinheiro, Bárbara; Salgado, António J.. "MSCs-Derived Exosomes: Cell-Secreted Nanovesicles with Regenerative Potential". Frontiers in Pharmacology 7 (2016): http://dx.doi.org/10.3389/fphar.2016.00231. 10.3389/fphar.2016.00231 Pires, Ana O.; Mendes-Pinheiro, Barbara; Teixeira, Fábio G.; Anjo, Sandra I.; Ribeiro-Samy, Silvina; Gomes, Eduardo D.; Serra, Sofia C.; et al. "Unveiling the Differences of Secretome of Human Bone Marrow Mesenchymal Stem Cells, Adipose Tissue-Derived Stem Cells, and Human Umbilical Cord Perivascular Cells: A Proteomic Analysis". Stem Cells and Development 25 14 (2016): 1073-1083. http://dx.doi.org/10.1089/scd.2016.0048. 10.1089/scd.2016.0048 Teixeira, Fábio G.; Panchalingam, Krishna M.; Assunção-Silva, Rita; Serra, Sofia C.; Mendes-Pinheiro, Bárbara; Patrício, Patrícia; Jung, Sunghoon; et al. "Modulation of the Mesenchymal Stem Cell Secretome Using Computer-Controlled Bioreactors: Impact on Neuronal Cell Proliferation, Survival and Differentiation". Scientific Reports 6 1 (2016): http://dx.doi.org/10.1038/srep27791. 10.1038/srep27791 Teixeira, Fábio G.; Panchalingam, Krishna M.; Anjo, Sandra Isabel; Manadas, Bruno; Pereira, Ricardo; Sousa, Nuno; Salgado, António J.; Behie, Leo A.. "Do hypoxia/normoxia culturing conditions change the neuroregulatory profile of Wharton Jelly mesenchymal stem cell secretome?". Stem Cell Research & Therapy 6 1 (2015): http://dx.doi.org/10.1186/s13287-015-0124-z. 10.1186/s13287-015-0124-z Salgado, Antonio J.; Sousa, Joao C.; Costa, Bruno M.; Pires, Ana O.; Mateus-Pinheiro, António; Teixeira, F. G.; Pinto, Luisa; Sousa, Nuno. "Mesenchymal stem cells secretome as a modulator of the neurogenic niche: basic insights and therapeutic opportunities". Frontiers in Cellular Neuroscience 9 (2015): http://dx.doi.org/10.3389/fncel.2015.00249. 10.3389/fncel.2015.00249 Teixeira, Fábio G.; Carvalho, Miguel M.; Neves-Carvalho, Andreia; Panchalingam, Krishna M.; Behie, Leo A.; Pinto, Luísa; Sousa, Nuno; Salgado, António J.. "Secretome of Mesenchymal Progenitors from the Umbilical Cord Acts as Modulator of Neural/Glial Proliferation and Differentiation". Stem Cell Reviews and Reports 11 2 (2014): 288-297. http://dx.doi.org/10.1007/s12015-014-9576-2. 10.1007/s12015-014-9576-2 Sevivas, N.; Serra, S. C.; Portugal, R.; Teixeira, F. G.; Carvalho, M. M.; Silva, N.; Espregueira-Mendes, J.; Sousa, N.; Salgado, A. J.. "Animal model for chronic massive rotator cuff tear: behavioural and histologic analysis". Knee Surgery, Sports Traumatology, Arthroscopy 23 2 (2014): 608-618. http://dx.doi.org/10.1007/s00167-014-3441-3. 10.1007/s00167-014-3441-3 Teixeira, Fábio G.; Carvalho, Miguel M.; Sousa, Nuno; Salgado, António J.. "Mesenchymal stem cells secretome: a new paradigm for central nervous system regeneration?". Cellular and Molecular Life Sciences 70 20 (2013): 3871-3882. http://dx.doi.org/10.1007/s00018-013-1290-8. 10.1007/s00018-013-1290-8 Salgado, A.J.; Oliveira, J.M.; Martins, A.; Teixeira, F.G.; Silva, N.A.; Neves, N.M.; Sousa, N.; Reis, R.L.. "Tissue engineering and regenerative medicine: Past, present, and future". International Review of Neurobiology 108 (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84884682307&partnerID=MN8TOARS. 10.1016/B978-0-12-410499-0.00001-0 Jung, Sunghoon; Teixeira, Fábio G; Panchalingam, Krishna M.; António José Braga Osório Gomes Salgado; Behie, Leo A.. "Potential Therapeutic Properties of Human Mesenchymal Stem Cells". Journal for Clinical Studies 4 6 (2012): 36-41. https://issuu.com/mark123/docs/jcs_-_volume_4_-_issue_6_-_nov_2012. Published M. Carvalho, Miguel; G. Teixeira, Fabio; L. Reis, Rui; Sousa, Nuno; J. Salgado, Antonio. "Mesenchymal Stem Cells in the Umbilical Cord: Phenotypic Characterization, Secretome and Applications in Central Nervous System Regenerative Medicine". Current Stem Cell Research & Therapy 6 3 (2011): 221-228. http://dx.doi.org/10.2174/157488811796575332. 10.2174/157488811796575332
Journal issue	Fábio G. Teixeira; Nuno Barbosa Rocha; Mónica Vieira. "Neuromodulation and Biomarkers in Neurodegenerative Diseases". Cells (2024): https://www.mdpi.com/journal/cells/special_issues/7V18L82642. Invited editor Fernandes, Ruben; Baylina Machado, Pilar; Fábio Gabriel Teixeira. "Stem Cells, Metabolism and Neurodegenerative Diseases". Cells (2022): https://www.mdpi.com/journal/cells/special_issues/stem_neuro. Editor "Special Issue "Personalized Care and Treatment Compliance in Chronic Conditions"". Journal of Personalized Medicine (2022): https://www.mdpi.com/journal/jpm/special_issues/treatment_compliance. Accepted • Editor Teixeira, Fábio G. "Stem Cells Secretome in CNS Pathological Conditions". Frontiers in Cellular Neuroscience (2020): https://www.frontiersin.org/research-topics/12524/stem-cells-secretome-in-cns-pathological-conditions.

Activities

Oral presentation

	Presentation title	Event name Host (Event location)
2022/10/10	Regenerative Medicine and EVs, held in ExoTECH – 2022, 10-12 October 2022 at AIIMS, New Delhi, India.	Invited Talk ExoTECH2022 (New Delhi, India)
2022/06/15	Multimodal Pharmacotherapies – seeking for a disease-modifying strategy for Parkinson’s Disease Treatment, held in iBIMED (June 15, 2022), University of Aveiro, Aveiro, Portugal.	Invited Talk (Aveiro, Portugal)
2022/03/20	N-acetylcysteine as Parkinson Disease Therapy: Creating a Strategy for Disease Modeling and Repair.	AD/PD 2022 ADVANCES IN SCIENCE & THERAPY. International Conference on Alzheimer’s and Parkinson’s Diseases and related neurological disorders. (Barcelona, Spain)
2020/09/30	Focused Ultrasound combined with Stem Cells Secretome and Pharmacotherapies: establishing a Multimodal path for Parkinson’s Disease repair, held at NeuroSpin (September 30, 2020), CEA, Paris, France.	Invited Talk (Paris, France)
2019/10/14	Stem Cells Secretome Combined with Pharmacotherapies as a Multimodal Strategy for Parkinson’s Disease Regenerative Medicine.	TERMIS-AP 2019, Brisbane, Australia (Brisbane, Australia)
2017/06/30	Impact of the Secretome of Human Mesenchymal Stem Cells on Parkinson’s Disease Regenerative Medicine: Neuronal differentiation, Brain Structure and Animal Behavior	TERMIS-EU (Tissue Engineering and Regenerative Medicine International Society 2017, Davos, Switzerland
2016/06/30	Exploring the therapeutic potential of Mesenchymal Stem Cells Secretome for Parkinson’s Disease Regenerative Medicine Applications	TERMIS EU (Tissue Engineering International and Regenerative Medicine Society) – UPPSALA, SWEDEN – 28 JUNE-1 JULY
2016/02/27	Mesenchymal Stem Cells Secretome as Modulator of Brain Repair: Effects on Parkinson’s Disease	Congress SPDMov 2016 - “Care in Parkinso Disease" (Portugal)
2015/12/01	Mesenchymal Stem Cells Secretome: a Modulator for Central Nervous System Regeneration?	Spinal Cord Injury Iberian Symposium – 2015 (SCiS-2015) (Lisbon, Portugal)
2015/09/10	Mesenchymal Stem Cells Secretome as Modulator of Brain Repair: Effects on Neurogenesis and Parkinson’s Disease Regeneration	4th TERMIS World Congress (Boston, United States)
2014/05/12	Mesenchymal Stem Cells Secretome: a new therapeutic tool for Central Nervous System repair?	6th meeting FIRST (Forum of Italian Researchers on Mesenchymal and Stromal Stem Cells) (Milan, Italy)
2014	Functionalized Gellan Gum Hydrogels and Cell-based Therapies in Spinal Cord Injury Regeneration.	Termis-EU Congress (Genova, Italy)
2013	Functional Gellan Gum Hydrogels and Cell based Therapies – A Novel Therapeutic Approach for Spinal Cord Injury Regeneration.	XIII Meeting of the Portuguese Society for Neurosciences (Portugal)
2011/06/10	Human Umbilical Cord Perivascular Stem Cells (HUCPVCs) and their Conditioned media increase Proliferation, Survival and Differentiation in the Dentate gyrus of Adult Rat Hippocampus	TERMIS EU 2011 Annual Meeting, Tissue Engineering & Regenerative Medicine International Society (Granada, Spain)
2011/04/28	Transplantation of Human Umbilical Cord Perivascular Stem Cells (HUCPVCs) and their Conditioned media enhances Proliferation, Survival and Differentiation in Central Nervous System	6th International Meeting SPCE-TC BIOCANT (Coimbra, Portugal)
2010/06/13	Secretome of Mesenchymal Progenitors of the Umbilical Cord as Modulator of Neural and Glial Survival, Viability and Differentiation	TERMIS EU 2010- Galway, Ireland - Tissue Engineering & Regenerative Medicine Society IEEE
2010	Secretome of Mesenchymal Progenitors of the Umbilical Cord as Modulator of Neural and Glial Survival, Viability and Differentiation	TERMIS- EU 2010 (Ireland)

Supervision

	Thesis Title Role	Degree Subject (Type) Institution / Organization
2023/12/01 - 2027/11/30	Does adult hippocampal gliogenesis modulate non-motor symptoms of Parkinson’s Disease? Understanding the role of newly-born glial cells in PD progression.” 2023.00893.BDANA from FCT Supervisor	Neurosciences (PhD) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal Laboratório Associado ICVS 3B's, Portugal University of Oxford Department of Physiology Anatomy and Genetics, United Kingdom
2022/12/01 - 2026/11/30	Modulation of adult hippocampal neurogenesis by antidepressants may aid the prevention of Parkinson's Disease Supervisor	Biomedicine (PhD) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal Laboratório Associado ICVS 3B's, Portugal Karolinska Institutet, Sweden
2022/12/01 - 2026/11/30	Repurposing multimodal strategies for Parkinson's Disease: creating the path for disease delay and repair? Supervisor	Biomedicine (PhD) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal University of Oxford Department of Physiology Anatomy and Genetics, United Kingdom
2022/10/01 - 2026/10/01	Repurposing Felodipine as a modulator of the Brain-Heart-Kidney axis Supervisor	Neurosciences (PhD) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal Universidade do Porto Faculdade de Medicina, Portugal
2022/07/01 - 2023/11/20	Safinamide Therapeutical Effects: Seeking for a disease-modifying strategy for Parkinson's Disease Supervisor	Metabolism - Biopathology and Experimentation (Master) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal Universidade do Porto Faculdade de Medicina, Portugal Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
2022/10/01 - 2023	“From the gut to the brain – exploring the role of the microbiome on Parkinson’s Disease” Supervisor	Biochemistry in Health (Master) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
2019/09 - 2021/07	Combining Stem Cells Secretome and N-acetylcysteine to Parkinson's Disease modeling and repair Supervisor	Health Sciences (Master) Laboratório Associado ICVS 3B's, Portugal Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal Universidade do Minho Escola de Medicina, Portugal
2019 - 2020/01/07	Combination of Mesenchymal Stem Cells Secretome and Pharmacotherapies for the Treatment of Parkinson's Disease? Supervisor	Mestrado Integrado em Medicina (Master) Universidade do Minho Escola de Medicina, Portugal
2017/09/04 - 2019/07/22	Mesenchymal Stem Cells Secretome-Derived Exosomes: Biological Nanovesicles for the Treatment of Parkinson's Disease? Supervisor	Master Program in Health Sciences (Master) Universidade do Minho Escola de Medicina, Portugal Laboratório Associado ICVS 3B's, Portugal Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2017/09/25 - 2018/06/13	Finding new secretomes for Parkinson’s disease Regenerative Medicine Applications Co-supervisor	Master Program in Health Sciences (Master) Universidade do Minho Escola de Medicina, Portugal Laboratório Associado ICVS 3B's, Portugal Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2017 - 2018	Combining Mesenchymal Stem Cells Secretome and Pharmacotherapies on Brain Structure and Animal Behaviour of a Rat Model of Parkinson's Disease? Supervisor	Mestrado Integrado em Medicina (Master) Universidade do Minho Escola de Medicina, Portugal
2017 - 2018	Mesenchymal Stem Cells Secretome as a therapeutic tool for Parkinson?s Disease repair: Impact on neurogenesis and glial cell densities. Co-supervisor	Mestrado Integrado em Medicina (Master) Universidade do Minho Escola de Medicina, Portugal
2015/09/21 - 2016/06/21	Mesenchymal Stem Cells Secretome in Parkinson’s Disease Regenerative Medicine Applications Co-supervisor	Master Program in Health Sciences (Master) Universidade do Minho Escola de Medicina, Portugal
2013 - 2013	Secretome of Mesenchymal Stem Cells: a new therapeutic tool for the regeneration and treatment of Parkinson’s disease? Co-supervisor	Mestrado Integrado em Medicina (Master) Universidade do Minho Escola de Medicina, Portugal

Event organisation

	Event name Type of event (Role)	Institution / Organization
2018/12/06 - 2018/12/07	1st international symposium Secretome With]Out[ Borders (2018/12/06 - 2018/12/07) Symposium (Member of the Organising Committee)	Laboratório Associado ICVS 3B's, Portugal Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal Universidade do Minho Escola de Medicina, Portugal
2017/07/06 - 2017/07/06	Round table discussion about the future challenges of Parkinson's disease: from basic science to clinical practice (Sponsored by Zambon) (2017/07/06 - 2017/07/06) Round table (Member of the Organising Committee)	Laboratório Associado ICVS 3B's, Portugal Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal Universidade do Minho Escola de Medicina, Portugal

Event participation

	Activity description Type of event	Event name Institution / Organization
2017/03/09 - 2017/03/09	Innovative Strategies for Central Nervous System Regenerative Medicine: a Focus on Parkinson’s Disease Seminar	III Jornadas da Saúde da EPB "o Saber e o Cuidar das Doenças Neurodegenerativas" Escola Profissional de Braga (EPB), Portugal

Jury of academic degree

	Topic Role	Candidate name (Type of degree) Institution / Organization
2024/03/13	"LRRK2 Mutations in Parkinson's disease: The Role in Autophagy and Lysosomal Function" (Thesis) Arguer	Marta Neves Madureira (PhD) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2020/07/27	Transplanting Glial Restricted Precursor into a model of cytogenesis ablation: uncovering the interplay between neuro-and gliogenesis (Thesis) Arguer	Joana Macedo (Master) Laboratório Associado ICVS 3B's, Portugal Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal Universidade do Minho Escola de Medicina, Portugal
2019/07/24	O impacto da sinalização astrocítica nos efeitos terapêuticos do secretoma de células mesenquimais estaminais no sistema nervoso central (Thesis) Main arguer	Jonas de Oliveira Campos (Master) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2019/07/22	Mesenchymal Stem Cells Secretome-Derived Exosomes: Biological Nanovesicles for the Treatment of Parkinson’s Disease? Supervisor	Helena Maria Vilaça Faria (Master) Laboratório Associado ICVS 3B's, Portugal Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal Universidade do Minho Escola de Medicina, Portugal
2018/06/13	Finding new secretomes for Parkinson’s disease Regenerative Medicine Applications Supervisor	Ana Verónica Mendes Domingues (Master) Universidade do Minho Escola de Medicina, Portugal
2016/10/12	Astrocyte-oligodendrocyte crosstalk in the context of astrogliosis (Thesis) Main arguer	Eva Daniela de Sousa Maia Carvalho (Master) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal Universidade do Porto Faculdade de Engenharia, Portugal

Association member

	Society Organization name	Role
2011/05/01 - Current	Society for Neuroscience (SFN)	Member

Course / Discipline taught

	Academic session	Degree Subject (Type)	Institution / Organization
2023 - Current	Biochemistry, Degree in Biomedical Laboratory Sciences, ESS\|P.Porto	(Licenciatura)	Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
2017 - Current	Speaker in the Advanced Course 'Fundamentals in Neuroscience'.	(Curso de doutoramento (conclusão de unidades curriculares))	Laboratório Associado ICVS 3B's, Portugal Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2023/11 - 2024	Physiotherapy in the Tegumentary, Myofascial, Circulatory, and Lymphatic Systems, Master degree in Dermatofunctional Physiotherapy. ESS\|P.Porto	(Mestrado)	Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
2023 - 2024	Biochemistry , CTeSP in Food and Health, ESS\|P.Porto	(Curso Técnico Superior Profissional)	Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
2023 - 2024	Applied Biochemistry, CTeSP in Radioactive Material in Biomedical Context, ESS\|P.Porto	(Curso Técnico Superior Profissional)	Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
2023 - 2024	Biomaterials and Biocompatibility, Degree in Medicinal Biotechnology, ESS\|P.Porto	(Licenciatura)	Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
2023 - 2024	Physiotherapy in the Metabolic and Endocrine Systems, Master degree in Dermatofunctional Physiotherapy. ESS\|P.Porto	(Mestrado)	Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
2023 - 2023	Microbial Biochemistry, Degree in Medicinal Biotechnology, ESS\|P.Porto	(Licenciatura)	Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
2022/05/13 - 2022/05/13	“From vascularization to neurodegeneration: what about Parkinson’s disease?”, Speaker in the Angiogenesis, Angiogenesis, and Cancer Inflammation I/II of the master and doctoral degree in Metabolism, Medicine, and Molecular Oncology.	(Curso de doutoramento (conclusão de unidades curriculares))	Universidade do Porto Faculdade de Medicina, Portugal
2020/03/04 - 2020/03/04	Speaker in the Medicine Course: "Stem Cell-Based Strategies for Central Nervous System Regenerative Medicine"	(Licenciatura)	Universidade do Porto Faculdade de Medicina, Portugal
2020/03/03 - 2020/03/03	Speaker in the advanced course in "Recent Trends in CNS Regenerative Medicine".	(Curso de doutoramento (conclusão de unidades curriculares))	Laboratório Associado ICVS 3B's, Portugal Universidade do Minho Escola de Medicina, Portugal Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2017/12/05 - 2017/12/05	Speaker in the Medicine Course: "Stem Cell-Based Strategies for Central Nervous System Regenerative Medicine: a focus on Parkinson’s Disease"	(Licenciatura)	Universidade do Minho Escola de Medicina, Portugal
2017/05/15 - 2017/06/02	Speaker in the advanced course in "Molecular and Cellular Analysis: essential toolkit for in vitro cell cultures, gene expression".	(Curso de doutoramento (conclusão de unidades curriculares))	Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal Universidade do Minho Escola de Medicina, Portugal Laboratório Associado ICVS 3B's, Portugal
2017/04/26 - 2017/05/12	Speaker in the advanced course "Hands-on the rodent brain".	(Curso de doutoramento (conclusão de unidades curriculares))	Laboratório Associado ICVS 3B's, Portugal Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal Universidade do Minho Escola de Medicina, Portugal
2017/04/03 - 2017/04/15	Speaker in the advanced course in "Pathogenesis of Neurodegenerative Diseases"	(Curso de doutoramento (conclusão de unidades curriculares))	Laboratório Associado ICVS 3B's, Portugal Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal Universidade do Minho Escola de Medicina, Portugal
2015/11/09 - 2015/11/20	Speaker in the advanced course in "Bioinformatics in Health Sciences".	(Curso de doutoramento (conclusão de unidades curriculares))	Laboratório Associado ICVS 3B's, Portugal Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal Universidade do Minho Escola de Medicina, Portugal
2013/03/04 - 2013/03/15	Speaker in the advanced course in "Stem Cells Get a Practical: approaches on stem cells isolation, characterization, and differentiation".	(Curso de mestrado (conclusão do curso de especialização))	Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal Laboratório Associado ICVS 3B's, Portugal Universidade do Minho Escola de Medicina, Portugal

Interview (newspaper / magazine)

	Activity description	Newspaper / Forum
2018/10/28	Interview about the role o stem cells secretome as tool for Parkinson's Disease repair	Jornal A VERDADE
2018	“New tool to revert Parkinson’s Disease Effects”	Correio do Minho
2017/04/13	Role of Stress in Parkinson's Disease	Jornal A VERDADE

Interview (tv / radio show)

	Program	Topic
2019/11/27 - 2019/11/27	Portugal em Direto	Mantero Belard Prize - Santa Casa da Misericórdia de Lisboa
2019/11/26 - 2019/11/26	SIC Notícias	Mantero Belard Prize - Santa Casa da Misericórdia de Lisboa.

Journal scientific committee

	Journal title (ISSN)	Publisher
2019 - Current	Stem Cell Research & Therapy (1757-6512)	Springer (Biomed Central Ltd.)
2019 - Current	Cells (2073-4409)	MDPI
2019 - Current	Cell Death and Disease (2041-4889)	Springer Science and Business Media LLC
2019 - Current	Frontiers in Cellular Neuroscience (1662-5102)	Frontiers Media SA
2019 - Current	Tissue Engineering and Regenerative Medicine (2212-5469)	Springer-Verlag
2018 - Current	Stem Cells International (1687-9678)	Hindawi Publishing Corporation (Sage-Hindawi Access to Research)
2018 - Current	BioDrugs (1179-190X)	Springer-Verlag
2016 - Current	Stem Cells Translational Medicine (2157-6580)	Wiley (John Wiley & Sons)
2020 - 2020	Frontiers in Cellular Neuroscience (1662-5102)	Frontiers Media SA

Other jury / evaluation

	Activity description	Institution / Organization
2020 - Current	Referee of Scientific Projects: National Science Centre, Poland – Mossakwski Medical Research Centre Polish Academy of Sciences.
2020 - Current	Referee of Scientific Projects: ANR - Agence Nationale De La Recherche, France.

Distinctions

Award

2023	PAPRE (Programme of Support for Publication in High Quality Scientific Journals) Instituto Politécnico do Porto, Portugal
2022	Prize Manuel Teixeira da Silva Universidade do Minho Escola de Medicina, Portugal
2019	Mantero Belard Prize Santa Casa da Misericórdia de Lisboa, Portugal
2016	Oral presentation Portuguese Society of Movement Disorders (SPDMov) Portuguese Society of Movement Disorders (SPDMov), Portugal
2014	Oral presentation on the 6th meeting FIRST Forum of Italian Researchers on Mesenchymal and Stromal Stem Cells, Italy

Other distinction

2021	Salary Grant Fundação para a Ciência e a Tecnologia, Portugal
2016	Post-Doctoral scholarship from the Portuguese Foundation for Science and Technology (FCT) (SFRH/BPD/118408/2016) Fundação para a Ciência e a Tecnologia, Portugal
2010	PhD scholarship from the Portuguese Foundation for Science and Technology (FCT) (SFRH/BD/69637/2010) Fundação para a Ciência e a Tecnologia, Portugal