Identification
Personal identification
- Full name
- Alexandra Gabriel Fraga
Citation names
- Fraga, Alexandra
- Fraga, Alexandra G.
Author identifiers
- Ciência ID
- 7E1F-EDE8-F19D
- ORCID iD
- 0000-0003-2029-1629
Knowledge fields
- Medical and Health Sciences - Health Sciences - Infectious Diseases
Languages
Language | Speaking | Reading | Writing | Listening | Peer-review |
---|---|---|---|---|---|
English (Mother tongue) | |||||
Portuguese | Proficiency (C2) | Proficiency (C2) | Proficiency (C2) | Proficiency (C2) | Proficiency (C2) |
Education
Degree | Classification | |
---|---|---|
2011 - 2019
Concluded
|
Host-pathogen interaction (Pós-doutoramento)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
|
|
2005 - 2010
Concluded
|
Health Sciences (Doutoramento)
Universidade do Minho Escola de Medicina, Portugal
|
|
1999 - 2003
Concluded
|
Applied Biology (Licenciatura)
Universidade do Minho Escola de Ciências, Portugal
|
Affiliation
Science
Category Host institution |
Employer | |
---|---|---|
2021 - Current | Auxiliary Researcher (Research) | Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal |
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal | ||
2019 - 2021 | Contracted Researcher (Research) | Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal |
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal |
Teaching in Higher Education
Category Host institution |
Employer | |
---|---|---|
2021 - Current | Assistant Professor (University Teacher) | Universidade do Minho Escola de Medicina, Portugal |
Universidade do Minho Escola de Medicina, Portugal |
Projects
Grant
Designation | Funders | |
---|---|---|
2023 - 2025 | In vitro screening-based selection and in vivo efficacy evaluation of bacteriophages as potential new assets in the topical
treatment of Buruli Ulcer disease.
GSK
Researcher
Universidade do Minho, Portugal
|
GlaxoSmithKline España |
2023/03 - 2024/08 | Immunometabolic requirements in Buruli Ulcer
2022.05266.PTDC
Principal investigator
|
Fundação para a Ciência e a Tecnologia
Ongoing
|
2021 - 2024 | A flexible platform for generating synthetic virus to control infectious diseases
La Caixa FITTED - HR21-00533
Researcher
|
Caixa d'Estalvis i Pensions de Barcelona
Ongoing
|
2021 - 2024 | Extracellular Vesicles as Potential Biomarkers in Fabry Disease Progression
Amicus_PL_2021
Researcher
|
Amicus Therapeutics SLU
Ongoing
|
2020/04/01 - 2022/09/30 | Reinforcing the response to COVID-19 pandemic by improving diagnostic tools and capacity (ReCOVMi)
NORTE-01-0145-FEDER-072555
Researcher
|
Fundação para a Ciência e a Tecnologia
Concluded
|
2020 - 2021 | Viral-Based Bioconjugation Platform (ViBBiP) for vaccines development against bacterial pathogens
ESCMID Research Grant 2020
Researcher
|
European Society of Clinical Microbiology and Infectious Diseases
Concluded
|
2018 - 2021 | lmmunogenetic determinants of susceptibility/resistance to Buruli ulcer: a family- and population-based study for a neglected
tropical disease
POCI-01-0145-FEDER-031312
Principal investigator
|
Fundação para a Ciência e a Tecnologia
Concluded
|
2016 - 2019 | Transcriptome Analysis of Animal Models of Spontaneous Healing of Buruli Ulcer
ERA-NET Infect-ERA (2015) grant BU_SPONT_HEAL
Post-doc
|
European Commission |
2016 - 2019 | Development of a novel colour-coded RING FISH method: an innovative tool for the detection of antibiotic resistant clinical
pathogens
241500
PTDC/DTP-PIC/4562/2014
Post-doc
|
Fundação para a Ciência e a Tecnologia
Concluded
|
2016 - 2019 | SynPhage: Construction of synthetic phages to combat infectious bacterial diseases
PTDC/BBB-BSS/6471/2014
Post-doc
|
Fundação para a Ciência e a Tecnologia
Concluded
|
2009 - 2012 | Buruli ulcer - from understanding the mechanisms of host resistance to the development of new interventions against emerging
mycobacterioses
Proc.Nº 94776
Researcher
|
Fundação Calouste Gulbenkian
Concluded
|
2006 - 2009 | Role of Interleukin-23 (IL-23) and IL-17 in the regulation of the immune response to the infection by Mycobacterium tuberculosis
PTDC/SAU-MII/70895/2006
Researcher
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
|
Fundação para a Ciência e a Tecnologia
Concluded
|
2002 - 2005 | Impact on public health of difficult-to-treat mycobacterioses: multi-resistant tuberculosis and Buruli ulcer
Proc. Nº 55762
Researcher
|
Fundação Calouste Gulbenkian
Concluded
|
Contract
Designation | Funders | |
---|---|---|
2021/01/01 - 2025/12/31 | ICVS/3B's - Laboratório Associado, Instituto de Ciências da Vida e da Saúde / Grupo de Investigação em Biomateriais, Biodegradaveis
e Biomiméticos
LA/P/0050/2020
Universidade do Minho, Portugal
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal |
Fundação para a Ciência e a Tecnologia
Ongoing
|
2019/01/01 - 2019/12/31 | ICVS/3B's - Associate Laboratory, Life and Health Sciences Research Institute / Biomaterials, Biodegradables and Biomimetics
Research Group
UID/Multi/50026/2019
Universidade do Minho, Portugal
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal |
Fundação para a Ciência e a Tecnologia
Concluded
|
Outputs
Publications
Book chapter |
|
Journal article |
|
Activities
Supervision
Thesis Title Role |
Degree Subject (Type) Institution / Organization |
|
---|---|---|
2019 - 2023 | Antimicrobial flexible coating material for the car sharing segment of the automotive industry.
Supervisor
|
Ciências da Saúde (PhD)
Universidade do Minho Escola de Medicina, Portugal
|
2017 - 2023 | Host genetics of resistance to Mycobacterium ulcerans: bridging clinical and cellular/animal models
Co-supervisor
|
Medicine (PhD)
Universidade do Minho Escola de Medicina, Portugal
|
2021 - 2022 | Single cell genomics in the host/pathogen interaction in Buruli Ulcer
Supervisor
|
Biomedical Engineering (Master)
Universidade do Minho Escola de Engenharia, Portugal
|
2021 - 2022 | Isolation of novel immunogenic protein carriers for vaccine development
Co-supervisor
|
|
2018 - 2019 | Sociodemographic and Clinical Variables in the Risk of Buruli Ulcer Development: a Systematic Review and Meta-Analysis
Supervisor
|
Medicine (Master)
Universidade do Minho Escola de Medicina, Portugal
|
2016 - 2016 | Efficacy of a new drug delivery system against Mycobacterium ulcerans infection
Supervisor
|
Bioquímica (Degree)
Universidade do Minho, Portugal
|
2016 - 2016 | Effect of corticosteroid-immunosuppression in guinea pig infected with Mycobacterium ulcerans
Supervisor
|
Bioquímica (Degree)
Universidade do Minho, Portugal
|
2013 - 2014 | The impact of immune gene polymorphisms in human Mycobacterium ulcerans infection
Supervisor
|
Ciências da Saúde (Master)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
|
2013 - 2014 | Characterization of the innate and acquired immune responses in the guinea pig during infection with Mycobacterium ulcerans
Co-supervisor
|
Biomedical Sciences (Master)
Universiteit Antwerpen, Belgium
|
2012 - 2012 | Buruli Ulcer: Comparative analysis of the murine and guinea pig model during infection with Mycobacterium ulcerans
Supervisor
|
Bioquímica (Degree)
Universidade do Minho, Portugal
|
2011 - 2012 | Study of the bactericidal activity of Elagic Acid against Mycobacterium tuberculosis
Supervisor
|
Medicina (Master)
Universidade do Minho Escola de Medicina, Portugal
|
Jury of academic degree
Topic Role |
Candidate name (Type of degree) Institution / Organization |
|
---|---|---|
2023 | Innate regulation of antifungal immunity in chronic pulmonary aspergillosis
(Thesis) Arguer
|
Cláudio Oliveira (PhD) |
2022 | Metabolic regulation of antifungal immunity: from basic mechanisms to clinical translation
(Thesis) Arguer
|
Samuel Gonçalves (PhD) |
2022 | Isolation and Characterization of extracellular vesicles from acute myeloid and bone marrow stromal cells
(Thesis) Arguer
|
Mafalda Barros (Master) |
2022 | Impact of food supplements on yeast chronological aging
(Thesis) Arguer
|
Sara Dourado (Master) |
2021/07 | Immunometabolic crosstalk between host and pathogen: unveiling novel
therapeutic approaches for visceral leishmaniasis
(Thesis) Arguer
|
Carolina Alves Ferreira (PhD)
Universidade do Minho Escola de Medicina, Portugal
|
2020/12 | Crosslinking Immunity and Metabolism during Leishmania Infection
(Thesis) Arguer
|
Inês Morais Mesquita (PhD)
Universidade do Minho Escola de Medicina, Portugal
|
2020/10 | Thymic infection and T cell immunodominance during Mycobacterium avium infection
(Thesis) Arguer
|
Bruno Miguel Cerqueira Rodrigues (PhD)
Universidade do Minho Escola de Medicina, Portugal
|
2016/11 | Immunogenetic determinants of susceptibility/resistance to Mycobacterium ulcerans infection: a population based study - Benin
biological bank on Buruli ulcer
(Thesis) Arguer
|
Carlos Alberto Pereira Capela (PhD)
Universidade do Minho Escola de Medicina, Portugal
|
Committee member
Activity description Role |
Institution / Organization | |
---|---|---|
2012 - Current | Member of Lab-PTBioNet: ICVS, UMinho representative: The Portuguese Biosafety Laboratory Network, Lab-PTBioNet, has the mission
to pomote a Biosafety laboratory policy and implement good Biosafety practices in all biological safety level 3 (BSL-3) laboratories
in Portugal.
Member
|
Instituto Nacional de Saúde Doutor Ricardo Jorge, Portugal |
2012 - Current | ICVS Biosafety Coordinator for BSL2/3: engaged in the implementation and dissemination of institutional and personal preventive
measures to promote the safe handling of biological agents and reduce the risk of individual exposure and avoid the risk of
intentional removal or misuse of a biological agent with the intention of causing harm.
Coordinator
|
|
2020 - 2021 | ICVS member of the COVID-19 diagnostic team: team leader of the inactivation station for COVID-19 diagnostics
Member
|
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal |
2019 - 2021 | Member of the Technical Committee: member of CT207 for the translation of ISO 35001:2021 - Biorisk management for laboratories
and other related organisations
Member
|
Distinctions
Award
2019 | Best Poster Award at Microbiotec19 for the work: Statins as new candidates for the treatment of Buruli Ulcer |
2010 | Pulido Valente Ciência Award with the work: Pathological role of interleukin 17 in mice subjected to repeated BCG vaccination after infection with Mycobacterium tuberculosis J. Exp. Med., 2010; 207(8): 1609-16 |
2010 | Best Paper Award from the Portuguese Society for Immunology, with the work: Pathological role of interleukin 17 in mice subjected to repeated BCG vaccination after infection with Mycobacterium tuberculosis. J. Exp. Med., 2010; 207(8): 1609-16 |
2006 | Excellence Award in Immunology Mário Arala Chaves at the Portuguese Society for Immunology, with the work: Th17 cells inducing a massive recruitment of neutrophils may play a role in Koch reaction. |