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Teresa Cunha-Oliveira, a biochemist and cell biologist, earned her PhD from the University of Coimbra (Portugal) in 2007. Her experimental work focused on identifying mitochondrial health biomarkers and developing mitochondria-targeted interventions for various human conditions. Recently, Teresa expanded her expertise into computational biology, data science, and research data management, gaining skills in SQL, Python, R, Microsoft Power BI. Microsoft Excel (Advanced) and MATLAB. She also contributed to implementing ISO 9001 quality management systems at the MitoXT service facility at the Center for Neuroscience and Cell Biology, University of Coimbra, having gained hands-on experience on improving research excellence and standardization. She also gained competencies in machine learning and data visualization aiming to further enhance the reproducibility of research data analysis and communication. Notably, Teresa is currently involved in two European projects: Era Chair EXCELScIOR: EXCELlent Science with Impact, Open and Reliable (GA 101087416) and PasGras - De-risking metabolic, environmental, and behavioral determinants of obesity in children, adolescents, and young adults (GA 101080329). Her bibliometric record includes an Hf index of 30 with 2305 citations (Scopus), 45 research papers, 16 reviews, and 17 book chapters. Her recent review on “Best practices for data management and sharing in experimental biomedical research” was published in Physiological Reviews, the top journal in Physiology (IF 2023 = 29.9). Teresa has supervised and co-supervised students at various institutions and academic levels, also securing two funded grants as principal investigator totaling €263.7k. She is active in training initiatives and served on various academic juries, demonstrating her commitment to mentoring the next generation of scientists. As an example, she co-organized several advanced courses on “Experimental Research Design” and led several workshops promoting best practices in biomedical research. She is particularly interested in creating user-friendly research data management workflows tailored to experimental biomedical scientists, aimed to enhance researcher engagement with best research practices for data handling and analysis . (Metrics updated on 26 July 2024)
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Identification

Personal identification

Full name
MARIA TERESA MARTINS DA CUNHA OLIVEIRA

Author identifiers

Ciência ID
7F1D-6E9A-C5EA
ORCID iD
0000-0002-7382-0339
Google Scholar ID
7h2nOmwAAAAJ
Researcher Id
A-3054-2009
Scopus Author Id
9744915800

Addresses

  • Centro de Neurociências e Biologia Celular da Universidade de Coimbra. MitoXT, UC-Biotech, Biocant Park, 3060-197, Cantanhede, Cantanhede, Portugal (Professional)

Knowledge fields

  • Natural sciences - Biological Sciences
  • Medical and Health Sciences - Basic Medicine
  • Medical and Health Sciences - Medical Biotechnology
  • Medical and Health Sciences - Health Sciences
  • Medical and Health Sciences - Basic Medicine
  • Medical and Health Sciences - Basic Medicine

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Education
Degree Classification
2007/12/01 - 2018/07/04
Concluded
 Post-Doc (Pós-doutoramento)
Centro de Neurociências e Biologia Celular da Universidade de Coimbra, Portugal
2008 - 2008
Concluded
 Experimentação Animal- FELASA C Accreditation (Pós-Graduação)
Centro de Neurociências e Biologia Celular da Universidade de Coimbra, Portugal

Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
Approved
2007/11/07
Concluded
 Biologia (Doutoramento)
Major in Especialidade: Biologia Celular
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"Neuronal Dysfunction Induced by Drugs of Abuse" (THESIS/DISSERTATION)
 Approved by Unanimity with Distinction (Maximum Grade)
2001 - 2003/05/29
Concluded
 Biologia Celular (Mestrado)
Universidade de Coimbra, Portugal
"Neurotoxicidade Induzida por Drogas de Abuso" (THESIS/DISSERTATION)
 Very Good (Maximum Grade)
1994 - 1999/11/24
Concluded
 Bioquímica (Licenciatura)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"Populational Genetics in STR's (Estudo de Genética Populacional em STR´s)" (THESIS/DISSERTATION)
 Good
Affiliation

Science

Category
Host institution 		Employer
2024/09/01 - 2027/08/31 Contracted Researcher (Research) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2019/02/01 - 2024/08/31 Contracted Researcher (Research) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Centro de Neurociências e Biologia Celular da Universidade de Coimbra, Portugal
2019/02/01 - 2022/01/31 Contracted Researcher (Research) Centro de Inovação em Biomedicina e Biotecnologia (CIBB), Portugal
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Others

Category
Host institution 		Employer
2018/07/06 - 2021/11/05 Principal Investigator of Grant POCI-01-0145-FEDER-029297 Fundação para a Ciência e a Tecnologia, Portugal
Centro de Neurociências e Biologia Celular da Universidade de Coimbra, Portugal
2016/11/01 - 2018/07/31 Head of MitoXT Service Facility Centro de Neurociências e Biologia Celular da Universidade de Coimbra, Portugal
Centro de Neurociências e Biologia Celular da Universidade de Coimbra, Portugal
2008/07/01 - 2010/08/31 Principal Investigator of Grant III/34/2008 Instituto de Investigação Interdisciplinar, Universidade de Coimbra, Portugal
Centro de Neurociências e Biologia Celular da Universidade de Coimbra, Portugal
Projects

Grant

Designation Funders
2023/03/01 - Current EXCELScIOR: EXCELlent Science with Impact, Open and Reliable
101087416
Researcher
Universidade de Coimbra, Portugal
 Horizon Europe
Ongoing
2019/02/01 - 2025/01/31 MitoProfiling- Mitochondrial Health Profiling. Applications in Toxicology and Personalized Medicine
DL 57/2016/CP1448/CT0016
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing

Contract

Designation Funders
2023/05 - Current PAS GRAS - De-risking metabolic, environmental and behavioral determinants of obesity in children, adolescents and young adults
101080329
Researcher
European Commission
Ongoing
2021/03/29 - Current SYNAPTIC VESICLE MATURATION AND ITS RELEVANCE FOR NEURODEGENERATION
PTDC/MED-NEU/8030/2020
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2021/01/01 - Current Organelle-targeted Radiocomplexes for Auger Therapy of Cancer
PTDC/MED-QUI/1554/2020
Researcher
Centro de Neurociências e Biologia Celular da Universidade de Coimbra, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2022/01/15 - 2025/01/14 Human Neuronal Cells Differentiated from Urine-derived Stem Cells as a Platform for Personalized Medicine in Amyotrophic Lateral Sclerosis
PTDC/BTM-ORG/0055/2021
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2022/01/01 - 2023/06/30 Role of mitochondrial-thiol homeostasis in neurodegeneration: implication for amyotrophic lateral sclerosis
EXPL/BTM-TEC/1407/2021
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2022 - 2023/06/30 Mitochondria as potential drivers of sex-specific microglia dysfunctional remodelling and anxiety caused by prenatal stress
EXPL/MED-NEU/1002/2021
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2018/07/06 - 2021/12/05 Development and validation of innovative screening methods for mitochondrial health modulators
PTDC/BTM-SAL/29297/2017
Principal investigator
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Universidade de Coimbra, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2018/05/01 - 2021/04/30 Development of Novel Mitochondria-Targeted Antioxidants for Improving SOD1-Familial Amyotrophic Lateral Sclerosis Phenotype
PTDC/MED-FAR/29391/2017
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Universidade do Porto, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2018/09/01 - 2019 Brain protection by Evolocumab in individuals at high risk for cardiovascular disease: from bench to bedside
PEPITA2018
Researcher
Universidade de Coimbra Faculdade de Medicina, Portugal
 Universidade de Coimbra Faculdade de Medicina
Concluded
2015/10 - 2018/09 MitoBOOST: A Next-Generation Therapeutics for Non-Alcoholic Fatty Liver Disease Based on Smart Antioxidant Delivery to Mitochondria
grant.Provided by PTCRIS: 141059
Researcher
Fundacao para a Ciencia e a Tecnologia
2015/10 - 2018/09 EXERCISING THE FUTURE: Voluntary Exercise During Gestational Diabetes as a Means to Improve Mitochondrial Function in the Offspring
grant.Provided by PTCRIS: 139707
Researcher
Centro de Neurociências e Biologia Celular da Universidade de Coimbra, Portugal
 Fundacao para a Ciencia e a Tecnologia
2015/01/01 - 2017 An Epigenetic Engineering Approach to Reverse the Parkinson Disease Cell State
Montepio_CNC
Researcher
Centro de Neurociências e Biologia Celular da Universidade de Coimbra, Portugal
 Fundação Montepio
Concluded
2013/05 - 2016/04 Pathophysiology of Persistent Doxorubicin Cardiotoxicity: a Mitochondrial-Epigenetics Link
PTDC/DTP-FTO/1180/2012
Researcher
Centro de Neurociências e Biologia Celular da Universidade de Coimbra, Portugal
 Fundacao para a Ciencia e a Tecnologia
Ongoing
2014/03/01 - 2015/09/30 Stemcell based platforms for regenerative and therapeutic medicine
CENTRO-07-ST24-FEDER-002008
4832
Post-doc Fellow
Centro de Neurociências e Biologia Celular da Universidade de Coimbra, Portugal
 European Regional Development Fund
Concluded
2013/12/01 - 2014/02/28 Role of mitochondrial p66Shc in drug-induced mitochondrial toxicity memory
grant.Provided by PTCRIS: 117912
Post-doc Fellow
Centro de Neurociências e Biologia Celular da Universidade de Coimbra, Portugal
 Fundacao para a Ciencia e a Tecnologia
2012/09/01 - 2013 Alpha-synuclein modifications in peripheral blood lymphocytes from sporadic and familial Parkinson's disease patients
PDCR02
Researcher
Universidade de Coimbra Faculdade de Medicina, Portugal
 Universidade de Coimbra Faculdade de Medicina
Concluded
2008/09 - 2010/08 Relationship Between Body Weight and the Development of Heroin Addiction: Role of Insulin and Leptin Hypothalamic Signalling Pathways
grant.Provided by PTCRIS: 126115
III/34/2008
Principal investigator
Instituto de Investigação Interdisciplinar, Universidade de Coimbra
2005/07 - 2008/06 Biochemical and Behavioural Study of Opioid-Cocaine Interactions
grant.Provided by PTCRIS: 58330
POCI/SAU-FCF/58330/2004
Researcher
Centro de Neurociências e Biologia Celular da Universidade de Coimbra, Portugal
 Fundacao para a Ciencia e a Tecnologia
2004/09/01 - 2005 Contribution of different subunits of the NMDA receptor to heroin cytotoxicity
GAI/06/2004
Researcher
Universidade de Coimbra Faculdade de Medicina, Portugal
 Universidade de Coimbra Faculdade de Medicina
Concluded
Outputs

Publications

Book
  1. Cunha-Oliveira, T.. Neuronal dysfunction induced by drugs of abuse- cellular and molecular approach (ISBN 9783639176698). Germany: VDM- Verlag Publishing. 2009.
    Published
Book chapter
  1. Alexandra C. de Lemos; José Carlos Santos Teixeira; Teresa Cunha-Oliveira. "Characterization of the Mitochondria Function and Metabolism in Skin Fibroblasts Using the Biolog MitoPlate S-1". 2025.
    10.1007/978-1-0716-4264-1_5
  2. Sónia A. Pinho; Georgina L. Gardner; Ricardo Alva; Jeff A. Stuart; Teresa Cunha-Oliveira. "Creating Physiological Cell Environments In Vitro: Adjusting Cell Culture Media Composition and Oxygen Levels to Investigate Mitochondrial Function and Cancer Metabolism". 2025.
    10.1007/978-1-0716-4264-1_9
  3. Gonçalo J.M. Afonso; Rui F. Simões; Sonia L.C. Pinho; Paulo J. Oliveira; Teresa Cunha-Oliveira. "Challenges in mitochondrial profiling during pre-clinical studies". 2023.
    10.1016/B978-0-323-88462-4.00002-X
  4. Jorge Henriques; Caio Ribeiro; Teresa Rocha; Paulo de Carvalho; Duarte, Ana I.; Freitas, Alex; Cunha-Oliveira, T.; Francisco Baptista Pereira. "Machine learning in the context of better healthcare in aging". In AGING: FROM FUNDAMENTAL BIOLOGY TO SOCIETAL IMPACT. Elsevier, 2022.
    In press
  5. Vega-Naredo, Ignacio; Oliveira, Gabriela; Cunha-Oliveira, Teresa; Serafim, Teresa; Sardão, Vilma A.; Oliveira, Paulo J.. "Analysis of Proapoptotic Protein Trafficking to and from Mitochondria". In Methods in Molecular Biology, 161-178. Springer US, 2021.
    Published • 10.1007/978-1-0716-1433-4_10
  6. # Cunha-Oliveira, T.; Rego, A. C.; Oliveira, C.R. Corresponding author: # Cunha-Oliveira, T.. "Cocaine as a Neurotoxin". In Handbook of Neurotoxicity,, edited by Kostrzewa, R.M.. Springer, 2021.
    Published • 10.1007/978-3-030-71519-9_81-1
  7. Ferreira, Luciana L.; Oliveira, Paulo J.; # Cunha-Oliveira, Teresa. Corresponding author: # Cunha-Oliveira, Teresa. "Epigenetics in Doxorubicin Cardiotoxicity". In Pharmacoepigenetics, edited by Cacabelos, Ramón, 837-846. Elsevier, 2019.
    Published • 10.1016/b978-0-12-813939-4.00033-4
  8. Abreu, P. L.; Ferreira, L. M. R.; Cunha-Oliveira, T.; Alpoim, M.C.; Urbano, A. M.. "HSP90: A Key Player in Metal-Induced Carcinogenesis?". In Heat Shock Protein 90 in Human Diseases and Disorders, edited by Dr. Punit Kaur. Springer International Publishing, 2019.
    Published • 10.1007/978-3-030-23158-3_11
  9. Simões, Rui F.; Cunha-Oliveira, Teresa; Costa, Cláudio F.; Sardão, Vilma A.; Oliveira, Paulo J.. "In Vitro Methodologies to Investigate Drug-Induced Toxicities". In Mitochondrial Dysfunction Caused by Drugs and Environmental Toxicants, 229-247. John Wiley & Sons, Inc., 2018.
    Published • 10.1002/9781119329725.ch14
  10. Ferreira, Luciana L.; Coelho, Ana Raquel; Oliveira, Paulo J.; # Cunha-Oliveira, Teresa. Corresponding author: # Cunha-Oliveira, Teresa. "Mitochondrial Toxicity Induced by Chemotherapeutic Drugs". In Mitochondrial Dysfunction Caused by Drugs and Environmental Toxicants, 593-612. John Wiley & Sons, Inc., 2018.
    Published • 10.1002/9781119329725.ch40
  11. Pereira, S.P.; # Cunha-Oliveira, T.. Corresponding author: # Cunha-Oliveira, T.. "Role of Mitochondria on the Neurological Effects of Cocaine". In The Neuroscience of Cocaine, 205-218. Elsevier, 2017.
    Published • 10.1016/b978-0-12-803750-8.00021-x
  12. # Cunha-Oliveira, T.. Corresponding author: # Cunha-Oliveira, T.. "Alucinogénios". In Toxicologia Forense, 233-247. Lisboa, Portugal: Pactor, 2015.
    Published
  13. # Cunha-Oliveira, Teresa; Rego, A. Cristina; Oliveira, Catarina R. Corresponding author: # Cunha-Oliveira, Teresa. "Cocaine as a Neurotoxin". In Handbook of Neurotoxicity, 277-297. New York, NY: Springer New York, 2014.
    Published • 10.1007/978-1-4614-5836-4_81
  14. Vega-Naredo, Ignacio; Cunha-Oliveira, Teresa; Serafim, Teresa L.; Sardao, Vilma A.; Oliveira, Paulo J.. "Analysis of Pro-apoptotic Protein Trafficking to and from Mitochondria". In Methods in Molecular Biology, 163-180. New York, United States: Springer New York, 2014.
    Published • 10.1007/978-1-4939-1875-1_14
  15. # Cunha-Oliveira, Teresa; Rego, Ana Cristina; Carvalho, Félix; Oliveira, Catarina R.. Corresponding author: # Cunha-Oliveira, Teresa. "Medical Toxicology of Drugs of Abuse". In Principles of Addiction, 159-175. USA: Elsevier, 2013.
    Published • 10.1016/B978-0-12-398336-7.00017-6
  16. # Cunha-Oliveira, T.; Rego, A.C.; Oliveira, C.R.. Corresponding author: # Cunha-Oliveira, T.. "Neurotoxicity of cocaine". In Cocaine Abuse:Pharmacology, Treatment and Relapse Prevention, 99-113. Nova Science Publishers, Inc., 2012.
    Published
  17. Cunha-Oliveira, Teresa; Ferreira, Ildete L; Rego, A Cristina. "Consequences of mitochondrial dysfunction in Huntington's Disease and protection via phosphorylation pathways". In Huntington's Disease - Core Concepts and Current Advances, edited by Tunali N.E., 361-390. InTech- Open Access Publisher, 2012.
    Published • 10.5772/32728
Conference abstract
  1. Cunha-Oliveira, T.; Naia, L.; Ferreira, I. L.; Rosenstock, T.; Duarte, A. I.; Ribeiro, M.; Laço, M.; et al. "Activation of IGF-1 and insulin signaling pathways ameliorate energy metabolism and mitochondrial function in Huntington’s disease human lymphoblasts". Paper presented in Neuroscience 2012- No. 154.05 Neuroscience Meeting Planner. https://goo.gl/iggUuL, New Orleans, 2012.
    Published
  2. Rosenstock, T.; Rodrigues, J.; Naia, L.; Cunha-Oliveira, T.. "Regulation of pyruvate dehydrogenase and mitochondrial function by histone deacetylase inhibitors in Huntington's disease". Paper presented in Neuroscience 2012. Program No. 154.25 Neuroscience Meeting Planner. Online. https://goo.gl/Vj8Qex, New Orleans, 2012.
    Published
  3. Cunha-Oliveira, T.; Viana, S.; Travassos, A. S.; Nunes, S.; Silva, C.; Rego, A. C.; Ali, S. F.; Fontes-Ribeiro, C.; Pereira, F. C.. "Acute methamphetamine intoxication evokes deregulation of striatal glutamatergic/gabaergic homeostasis in mice". Paper presented in FENS 2012 (http://fens.ekonnect.co/FENS_331/poster_35282/program.aspx), Barcelona, 2012.
    Published
  4. Rosenstock, T.; Rodrigues, J.; Naia, L.; Cunha-Oliveira, T.; Rego, A. C.. "Impact of histone deacetylase inhibitors on pyruvate dehydrogenase and mitochondrial function in cellular models of Huntington's disease". Paper presented in FENS 2012 (http://fens.ekonnect.co/FENS_331/poster_32159/program.aspx), Barcelona, 2012.
    Published
  5. Pereira, F. C.; Viana, S.; Nunes, S.; Cunha-Oliveira, T.; Travassos, A. S.; Silva, C.; Silva, A. M.; et al. "Effect of a single high-dose of methamphetamine on striatal alpha-synuclein, RAGE, neurochemical levels and motor coordination in mice". Paper presented in Neuroscience 2011. Neuroscience Meeting Planner https://goo.gl/sB3eRi, Washington, D. C., 2011.
    Published
  6. Cunha-Oliveira, T.; Ferreira, I. L.; Nascimento, M. V.; Ribeiro, M.; Proença, M. T.; Januário, C.; Oliveira, C. R.; Rego, A. C.. "Impairment of energy metabolism in Huntington's Disease human cybrids". Paper presented in Neuroscience 2011. Neuroscience Meeting Planner https://goo.gl/P2BFeS, Washington, D. C., 2011.
    Published
  7. Cunha-Oliveira, T.; Rego, A.C.; Garrido, J.; Borges, F.; Macedo, T.; Oliveira, C.R.. "Neurotoxicity of sequential and simultaneous exposure to heroin and cocaine in rat cortical neurons". Amsterdão, 2010.
  8. Cunha-Oliveira, T.; Rego, A.C.; Garrido, J.; Borges, F.; Macedo, T.; Oliveira, C.R.. "Neurotoxicity of cocaine-opioid combinations in rat cortical neurons". Chicago, 2009.
  9. Cunha-Oliveira, T.; Rego, A.C.; Macedo, T.; Oliveira, C.R.. "Adaptation to oxidative stress in the chronic effects of cocaine and amphetamine". Vilamoura, 2007.
  10. Cunha-Oliveira, T.; Rego, A.C.; Macedo, T.; Oliveira, C.R.. "Changes in toxicity in PC12 cells chronically exposed to opioid and stimulant drugs of abuse and hydrogen peroxide". Paper presented in Neuroscience 2006: Annual Meeting of the Society for Neuroscience, Altanta, 2006.
    Published
  11. Cunha-Oliveira, T.; Rego, A.C.; Macedo, T.; Oliveira, C.R.. "Heroin-induced degeneration of cortical neurons involves mitochondria-dependent apoptosis". Paper presented in Neuroscience 2005- Annual Meeting of the Society for Neuroscience, Washington, DC, 2005.
    Published
  12. Cunha-Oliveira, T.; Rego, A.C.; Morgadinho, M.T.; Sarmento, A.; Macedo, T.; Oliveira, C.R.. "Differential cytotoxic responses of PC12 cells chronically exposed to psychostimulants or to hydrogen peroxide". Paper presented in 8th Meeting of the Portuguese Neuroscience Society, Luso, 2005.
    Published
  13. Cunha-Oliveira, T.; Rego, A.C.; Macedo, T.; Oliveira, C.R.. "Heroin neurotoxicity involves apoptosis and increased reactive oxygen species in rat cortical neurons". Paper presented in 4th FENS Forum, Lisbon, 2004.
    Published
  14. Rego, A.C.; Cunha-Oliveira, T.; Macedo, T.; Oliveira, C.R.. "Involvement of mitochondrial apoptotic pathway in PC12 cell death induced by heroin, amphetamine and cocaine". Paper presented in 3rd FENS Forum, Paris, 2002.
    Published
Conference paper
  1. Sónia A. Pinho; Paulo J. Oliveira; Teresa Cunha-Oliveira. "Metabolic Priming in NHDF Reveals Redox-Dependent Adaptations". Paper presented in MAC2023: Mitochondria in Aging, Cancer and Cell Death, Coimbra, 2023.
    Published • 10.1016/j.bbadis.2024.167418
  2. Sónia A. Pinho; Kátia Ribeiro; Paulo J. Oliveira; Teresa Cunha-Oliveira. "Unraveling Heterogeneity of Cellular Redox Responses During Metabolic Priming". Paper presented in MAC2023: Mitochondria in Aging, Cancer and Cell Death, Coimbra, 2023.
    Published • 10.1016/j.bbadis.2024.167391
  3. Pinho, Sónia A.; Deus, C. M.; Pinho, S. L.; Oliveira, P. J.; Cunha-Oliveira, Teresa. Corresponding author: Cunha-Oliveira, Teresa. "Phenotypical alterations in human skin fibroblasts under different metabolic conditions". Paper presented in 56th Annual Scientific Meeting of the European Society of Clinical Investigation, 8–10 June 2022, Bari, Italy, Bari, 2022.
    Published • 10.1111/eci.13796
  4. Silva, Filomena S.G.; Cunha-Oliveira, T.; Franco da Silva, Daniela; Segura, Luis; Marques, Ricardo; Rosenstock, Tatiana; Oliveira, Paulo J. (E41F-4FB7-5948). "Oxidative Stress Profile in Lymphoblasts from Amyotrophic Lateral Sclerosis Patients with SOD1 Mutations and Unknown mutations". Paper presented in 55th Annual Meeting of the European Society for Clinical Investigation, 2021.
    Published
  5. Pinho, Sónia Andreia; Costa, Cláudio F.; Miranda-Santos, I.; Pinho, Sonia L. C:; Oliveira, Paulo J. (E41F-4FB7-5948); Cunha-Oliveira, T.. "Manipulation of glucose availability promotes different in vitro redox environments in human dermal fibroblasts". Paper presented in 55th Annual Meeting of the European Society for Clinical Investigation, 2021.
    Published
  6. Deus, Cláudia; Pereira, Susana P.; Cunha-Oliveira, T.; Teixeira, J.; Simões, Rui; Cagide, F.; Benfeito, S.; et al. "A novel phenolic acid-based mitochondria-targeted antioxidant improves cellular responses to oxidative stress in fibroblasts from sporadic Parkinson’s disease patients". Paper presented in 55th Annual Meeting of the European Society for Clinical Investigation, 2021.
    Published
  7. Deus, Claudia; Pereira, Susana P.; Cunha-Oliveira, T.; Teixeira, J.; Simões, R.; Cagide, F.; Benfeito, S.; et al. "AntiOxCIN4 a new mitochondriotropic derivative based on the natural polyphenol caffeic acid reverts cellular and mitochondrial metabolic defects of fibroblasts from idiopathic Parkinson's Disease". Paper presented in 55th Annual Meeting of the European Society for Clinical Investigation, 2021.
    Published
  8. Miranda-Santos, I.; Pereira, Carolina; Pinho, Sónia Andreia; Oliveira, Paulo J.; Cunha-Oliveira, T.. "Visualization of metabolic rewiring of NHDF cells in response to extracellular glucose concentration". Paper presented in 55th Annual Meeting of the European Society for Clinical Investigation, 2021.
    Published
  9. Simões, Rui; Cunha-Oliveira, T.; Oliveira, Paulo J. (E41F-4FB7-5948); Pereira, F.. "Evaluation of 6-Hydroxydopamine and Rotenone in Vitro Neurotoxicity in SH-SY5Y Cells using Computational Applied Statistics". Paper presented in 55th Annual Meeting of the European Society for Clinical Investigation, 2021.
    Published
  10. *Cunha-Oliveira, T. (7F1D-6E9A-C5EA); Carvalho, M.; Sardão, V.; Oliveira, Paulo J.; Silva, Filomena S.G.. "Multi-dimensional Analysis of Metabolic and Mitochondrial Dysfunction Parameters in Lymphoblasts from Amyotrophic Lateral Sclerosis Patients". Paper presented in 55th Annual Meeting of the European Society for Clinical Investigation, 2021.
    Published
  11. *# Cunha-Oliveira, T. (7F1D-6E9A-C5EA). "Good practices with experimental data". Paper presented in 55th Annual Meeting of the European Society for Clinical Investigation, 2021.
    Published
  12. Silva, Filomena S.G.; Cunha-Oliveira, T.; Oliveira, Paulo J. (E41F-4FB7-5948). "Glycolytic fluxes and metabolic profiles distinguish amyotrophic lateral sclerosis patients from healthy controls". Paper presented in ESCI Virtual Meeting 2020 – COVID19 edition, 2020.
    Published
  13. Cunha-Oliveira, T.; Oliveira, Paulo J. (E41F-4FB7-5948); Silva, Filomena S.G.. "Exploratory analysis of mitochondrial metabolism in lymphoblasts from Amyotrophic Lateral Sclerosis patients to reveals discriminant biomarkers.". Paper presented in ESCI Virtual Meeting 2020 – COVID19 edition, 2020.
    Published
  14. Afonso, Gonçalo; Inês Miranda-Santos; Carvalho, RA; Carvalho, R; Carvalho Rui; Oliveira, Paulo J. (E41F-4FB7-5948); Cunha-Oliveira, T.. "Impact of Rebaudioside A in the metabolism of breast cancer cells and assessment of its chemotherapeutic potential". Paper presented in ESCI Virtual Meeting 2020 – COVID19 edition, 2020.
    Published
  15. Cunha-Oliveira, T.; Silva, Filomena S.G.; Pinho, Sónia Andreia; Costa, Cláudio F.; Inês Miranda-Santos; Oliveira, Paulo J. (E41F-4FB7-5948). "Mitochondria as biosensors for disease staging and therapeutic response". Paper presented in ESCI Virtual Meeting 2020 – COVID19 edition, 2020.
    Published
  16. Simões, Rui F.; Ferrão, Rafaela; Oliveira, Paulo J. (E41F-4FB7-5948); Cunha-Oliveira, T.. "Differentiated SH-SY5Y cells as a cellular model to study mitochondrial physiology and dynamics". Paper presented in ESCI Virtual Meeting 2020 – COVID19 edition, 2020.
    Published
  17. Simões, Rui F.; Cunha-Oliveira, T.; Oliveira, Paulo J. (E41F-4FB7-5948); Pereira, Francisco B.. "Non-supervised analysis of neurotoxicity of mitochondrial poisons 6-OHDA and Rotenone.". Paper presented in ESCI Virtual Meeting 2020 - COVID19 edition, 2020.
    Published
  18. Pino, Rute; Cunha-Oliveira, T.; Carvalho, Filipa S; Garcia, Rita; Burgeiro, Ana; Lourenço, Nuno; Carvalho, RA; Carvalho, R; Carvalho Rui; Oliveira, Paulo J. (E41F-4FB7-5948). "A Data Science Approach to Sub-chronic Doxorubicin Cardiotoxicity Reveals Hidden Patterns of Metabolic Remodeling". Paper presented in ESCI Virtual Meeting 2020 - COVID19 edition, 2020.
    Published
  19. Pino, Rute; Simões, Rui F.; Maurício Moreira-Soares; Cunha-Oliveira, T.; Kovarova, Jaromira; Neuzil, Jiri; Travasso, Rui; Oliveira, Paulo J. (E41F-4FB7-5948); Pereira, Francisco B.. "Data Extraction from Mitochondrial Motility Tracking using Computational Algorithms". Paper presented in ESCI Virtual Meeting 2020 – COVID19 edition, 2020.
    Published
  20. Pinho, Sónia Andreia; Inês Miranda-Santos; Costa, Cláudio F.; Olivia Bagshaw; Valente, Andrew; Stuart, Jeffrey; Oliveira, Paulo J. (E41F-4FB7-5948); Cunha-Oliveira, T.. "Morphological and functional mitochondrial remodeling in human skin fibroblasts cultured with different metabolic fuels.". Paper presented in ESCI Virtual Meeting 2020 – COVID19 edition, 2020.
    Published
  21. Grilo, Luis; Martins, João D.; Cavallaro, Chiara; Baldeiras, Inês; Cunha-Oliveira, T.; Ford, S.; Nathanielsz, P.W.; Oliveira, Paulo J. (E41F-4FB7-5948); Pereira, Susana P.. "Maternal obesity-induced oxidative damage impairs macroautophagy and unbalances mitochondrial dynamics". Paper presented in ESCI Virtual Meeting 2020 – COVID19 edition, 2020.
    Published
  22. Ferrão, R.; Oliveira, P. J.; Cunha-Oliveira, T.. "Comparative analysis of drugs of abuse toxicity in differentiated SH-SY5Y cells". Paper presented in 53rd Annual Meeting of the European Society for Clinical Investigation (ESCI), Coimbra, 2019.
  23. Pino, R.; Cunha-Oliveira, T.; Carvalho, F. S.; Garcia, R.; Burgeiro, A.; Carvalho, R. A.; Oliveira, P. J.; Lourenço, N.. "Uncovering hidden patterns in biological datasets to identify metabolic alterations caused by acute and sub-chronic DOX treatments". Paper presented in 53rd Annual Meeting of the European Society for Clinical Investigation (ESCI), Coimbra, 2019.
  24. Simoes, R. F.; Cunha-Oliveira, T.; Kovarova, J.; Neuzil, J.; Oliveira, P. J.; Pereira, F. B.. "Early mitochondrial metabolism and dynamics changes as predictors of neurodegeneration and neuronal cell death". Paper presented in 53rd Annual Meeting of the European Society for Clinical Investigation (ESCI), Coimbra, 2019.
  25. Deus, C. M.; Pereira, S. P.; Cunha-Oliveira, T.; Benfeito, S.; Cagide, F.; Borges, F.; Raimundo, N.; Oliveira, P. J.. "Human skin fibroblasts from sporadic Parkinson’s disease patients as a surrogate to measure the efficacy of novel mitochondria-directed antioxidant therapy". Paper presented in 53rd Annual Meeting of the European Society for Clinical Investigation (ESCI), Coimbra, 2019.
  26. Silva, F. S. G.; Bento, G.; Cunha-Oliveira, T.; Oliveira, P. J.. "Influence of SOD1 mutation on lymphoblast respiration and glycolytic rates from amyotrophic lateral sclerosis patients". Paper presented in 53rd Annual Meeting of the European Society for Clinical Investigation (ESCI), Coimbra, 2019.
  27. Grilo, L.; Pereira, S.; Martins, J.D.; Cavallaro, C.H.; Cardoso, I.; Baldeiras, I.; Cunha-Oliveira, T.; et al. "Adaptações na fosforilação oxidativa hepática provocadas pela obesidade durante a gravidez num modelo ovino". Paper presented in Congresso Português de Diabetes, Vilamoura, 2019.
    Published
  28. Cardoso, I.; Cunha-Oliveira, T.; Pereira, S.P.; Pankey, C.; Wang, Q.; Considine, M.M.; Ford, S.; Nathanielsz, P. W.; Oliveira, P. J.. "Maternal Obesity (MO) in an Ovine Model Results in Disruption of Offspring (F1) Mitochondrial Respirasomes". Paper presented in SRI 66th Annual Scientific Meeting (https://www.abstractsonline.com/pp8/#!/6816/presentation/3950), Paris, 2019.
    Published
  29. Rui F Simões; Teresa Cunha-Oliveira; Paulo J Oliveira; Francisco B Pereira. "Optimization of experimental and computational processes to study mitochondrial trafficking and metabolic biomarkers". Paper presented in 52nd Meeting of the European Society for Clinical Investigation, Barcelona, 2018.
    Published
  30. Cardoso, I.; Cunha-Oliveira, T.; Pinho, S.A.; Cavallaro, C.H.; Baldeiras, I.; Pereira, S.P.; Ford, S.; Nathanielsz, P. W.; Oliveira, P.J.. "Maternal obesity (MO) in sheep alters offspring mitochondrial hepatic biology and redefines the protein acetylation pattern". Paper presented in 52nd Meeting of the European Society for Clinical Investigation, Barcelona, 2018.
    Published
  31. Deus, C. M.; Pereira, S. P.; Cunha-Oliveira, T.; Benfeito, S.; Cagide, F.; Borges, F.; Raimundo, N.; Oliveira, P.J.. "Targeting dietary antioxidants to mitochondria ameliorate metabolic alterations of skin fibroblasts from patients with sporadic Parkinson’s Disease". Paper presented in 52nd Meeting of the European Society for Clinical Investigation, Barcelona, 2018.
    Published
  32. Pereira, S.P.; Cavallaro, C.H.; Grilo, L.; Martins, J.D.; Cardoso, I.; Baldeiras, I.; Cunha-Oliveira, T.; et al. "Mitochondrial Changes in the Maternal Liver in a Model of Obesity (MO) During Pregnancy". Paper presented in 52nd Meeting of the European Society for Clinical Investigation, Barcelona, 2018.
    Published
  33. Cardoso, I.; Cunha-Oliveira, T.; Pinho, S.A.; Cavallaro, C.H.; Baldeiras, I.; Pereira, S. P.; Ford, S.; Nathanielsz, P. W.; Oliveira, P.J.. "Impacto da obesidade gestacional na função mitocondrial hepática fetal num modelo ovino". Paper presented in 14º Congresso Português de Diabetes, Vilamoura, 2018.
    Published
  34. Fonseca, A.C.R.; Burgeiro, A.; Dias, C.; Costa-Nunes, J.; Seraphim, P.; Cunha-Oliveira, T.; Oliveira, P. J.; et al. "O tecido adiposo epicardial é bioenergeticamente mais activo do que o tecido adiposo subcutâneo". Paper presented in 14º Congresso Português de Diabetes, Vilamoura, 2018.
    Published
  35. Grilo, L.; Pereira, S.P.; Cavallaro, C.H.; Cardoso, I.; Baldeiras, I.; Cunha-Oliveira, T.; Martins, J.D.; et al. "Alterações Mitocondriais no Fígado Materno num Modelo de Obesidade Gestacional". Paper presented in 14º Congresso Português de Diabetes, Vilamoura, 2018.
    Published
  36. Pereira, S.P.; Nijland, M. J.; Tavares, L. C.; Duarte, A. I.; Baldeiras, I.; Cunha-Oliveira, T.; Santos, M. S.; et al. "Diabetes e doença cardíaca: uma herança da vida intrauterina?". Paper presented in 14º Congresso Português de Diabetes, Vilamoura, 2018.
    Published
  37. Cardoso, I.; Cavallaro, C.H.; Pinho, S.A.; Baldeiras, I.; Pereira, S.P.; Cunha-Oliveira, T.; Smith, A. M.; et al. "Maternal Obesity (MO) in Sheep Leads to Offspring (F1) Lobe-Dependent Impairment of Mitochondrial Hepatic Respiratory Chain Activity and Antioxidant Enzyme Activity". Paper presented in SRI 65th Annual Scientific Meeting, San Diego, 2018.
    Published
  38. Pereira, S.P.; Cavallaro, C.H.; Grilo, L.; Cardoso, I.; Baldeiras, I.; Cunha-Oliveira, T.; Smith, A. M.; et al. "Maternal Nutrient Excess and Obesity (MO) in Ewes during Pregnancy Leads to Alterations in Hepatic Mitochondrial Biology and Redox Balance". Paper presented in SRI 65th Annual Scientific Meeting, San Diego, 2018.
    Published
  39. Abreu, P. L.; Cunha-Oliveira, T.; Ferreira, L. M. R.; Urbano, A. M.. "Exposure of Human Bronchial Epithelial Cells to the Lung Carcinogen Hexavalent Chromium Confers Resistance to Thermal Shock and Interferes with the Stress Response". Paper presented in 51st Annual Meeting of the European Society for Clinical Investigation, Genoa, 2017.
    Published
  40. Pereira, S.P.; Nijland, M. J.; Tavares, L. C.; Duarte, A. I.; Baldeiras, I.; Cunha-Oliveira, T.; Santos, M. S.; et al. "Remodeling of Cardiac Mitochondrial Profile in the Fetal Baboon by Moderate Global Maternal Nutrient Reduction". Paper presented in 51st Annual Meeting of the European Society for Clinical Investigation, Genoa, 2017.
    Published
  41. Abreu, P. L.; Cunha-Oliveira, T.; Ferreira, L. M. R.; Urbano, A. M.. "Exposure of human bronchial epithelial cells to the lung carcinogen hexavalent chromium confers resistance to thermal shock and interferes with the stress response". Genoa, 2017.
    Published
  42. Ferreira, L. L.; Cunha-Oliveira, T.; Oliveira, P. J.. "Single nanomolar treatment with doxorubicin triggers mitochondrial adaptative responses in rat H9c2 cardiomyoblasts". Paper presented in Annual Meeting of the European Society for Clinical Investigation, Génova, 2017.
    Published
  43. Cunha-Oliveira, T.; Coelho, A. R.; Deus, C. M.; Oliveira, P. J.. "Mitochondrial dysfunction and p53 signaling in mouse stem cell-derived cardiomyocytes exposed to doxorubicin". Paper presented in Annual Meeting of the European Society for Clinical Investigation, Génova, 2017.
    Published
  44. Serafim, T. L.; Cunha-Oliveira, T.; Sardao, V. A.; Deus, C. M.; Cardoso, I.; Pinho, S.; Yang, S.; et al. "Maternal obesity (MO) in sheep decreases fetal hepatic mitochondrial respiratory chain activity and total mitochondrial lipids". Paper presented in Annual Meeting of the European Society for Clinical Investigation, Génova, 2017.
    Published
  45. Deus, C. M.; Pereira, S. P.; Cunha-Oliveira, T.; Oliveira, P. J.. "Altered metabolism and oxidative stress in skin fibroblasts from Parkinson's disease patients". Paper presented in Annual Meeting of the European Society for Clinical Investigation, Génova, 2017.
    Published
  46. Pereira, S. P.; Serafim, T. L.; Cunha-Oliveira, T.; Deus, C. M.; Starostina, I. G.; Ivanova, V. V.; Rizvanov, A. A.; Oliveira, P. J.. "Metabolic remodeling of human skin fibroblasts as model for studying mitochondrial diseases and drug-induced toxicity". Paper presented in 50th Annual Meeting of the European Society for Clinical Investigation, Paris, 2016.
    Published
  47. Ferreira, A. M.; Simoes, R. F.; Vilaca, A.; Carvalho, F. S.; Garcia, R.; Burgeiro, A.; Cunha-Oliveira, T.; Oliveira, P. J.. "Decreased global DNA methylation levels and gene expression patterns related metabolic end epigenetic remodeling enzymes are observed after Doxorubicin sub-chronic treatment"". Paper presented in 50th Annual Meeting of the European Society for Clinical Investigation, Paris, 2016.
    Published
  48. Abreu, P. L.; Cunha-Oliveira, T.; Ferreira, L. M. R.; Urbano, A. M.. "Exposure of human epithelial bronchial cells to hexavalent chromium, a lung carcinogen, downregulates HSP90a and confers resistance to stress". Paper presented in 5th CIMAGO congress, Coimbra, 2016.
    Published
  49. Cunha-Oliveira, T.. "Causes and consequences of mitochondrial dysfunction induced by drugs of abuse". Paper presented in Annual Meeting of the European Society for Clinical Investigation, Paris, 2016.
    Published
  50. Serafim, T. L.; Cunha-Oliveira, T.; Deus, C. M.; Oliveira, P. J.; Yang, S. S.; Tuerxun, A.; Odhiambo, F.; et al. "Maternal Obesity (MO) in Sheep Decreases Fetal Hepatic Mitochondrial Respiratory Chain Activity". Montreal, 2016.
    Published
  51. Pereira, S. P.; Tavares, L. C.; Duarte, A. I.; Cunha-Oliveira, T.; Santos, M. S.; Baldeiras, I.; Clarke, G.; et al. "Maternal nutrition and fetal mitochondrial fitness". Paper presented in Annual Meeting of the European Society for Clinical Investigation, 2016.
    Published
  52. Serafim, T. L.; Cunha-Oliveira, T.; Sardao, V. A.; Deus, C.; Greene, A.; Perkins, E.; Oliveira, P. J.. "Mitochondrial characterization of human breast cancer cell lines for in vitro cancer research". Paper presented in Cancer Epigenetics and Metabolism, Cantanhede, 2015.
    Published
  53. Ferreira, L. L.; Cunha-Oliveira, T.; Oliveira, P. J.. "Doxorubicin treatment induces persistent alterations in cardiomyoblast mitochondrial gene expression". Paper presented in Annual Meeting of the European Society for Clinical Investigation, 2015.
    Published
  54. Ferreira, A. M.; Vilaca, A.; Carvalho, F. S.; Garcia, R.; Burgeiro, A.; Cunha-Oliveira, T.; Oliveira, P. J.. "Doxorubicin decreases global DNA methylation levels, depletes mtDNA and causes down-regulation of transcripts for metabolic end epigenetic remodeling enzymes". Paper presented in Cancer Metabolism and Epigenetics, Cantanhede, 2015.
    Published
  55. Rego, Ana Cristina; Rodrigues, Joana; Cunha-Oliveira, Teresa; Ribeiro, Márcio; Rosenstock, Tatiana R.; Naia, Luana; Oliveira, Ana Margarida; Hayden, Michael R.. "Deficits of pyruvate dehydrogenase and mitochondrial dysfunction in Huntington's disease — role of histone deacetylase inhibitors". 2014.
    Published • 10.1016/j.bbabio.2014.05.003
  56. Ferreira, L. L.; Cunha-Oliveira, T.; Oliveira, P. J.. "Persistent effects in mitochondrial genes transcription after incubation of H9c2 cells with the anticancer drug Doxorubicin: an epigenetic origin?". Paper presented in Annual Meeting of the European Society for Clinical Investigation, 2014.
    Published
  57. Cunha-Oliveira, Teresa; Silva, Lisbeth; Silva, Ana Maria; Moreno, António J; Oliveira, Catarina R.; Santos, Maria S.. "Mitochondrial complex I dysfunction induced by cocaine and cocaine plus morphine in brain and liver mitochondria". Paper presented in Annual Meeting of the European Society for Clinical Investigation, Albufeira, 2013.
    Published • 10.1111/eci.12060
  58. Moreira, A. C.; Branco, A. F.; Sampaio, S. F.; Cunha-Oliveira, T.; Martins, T. R.; Holy, J.; Oliveira, P. J.; Sardao, V. A.. "Involvement mitochondrial apoptosis-inducing factor in doxorubicin-induced cardiotoxicity". Paper presented in Annual Meeting of the European Society for Clinical Investigation, Utrecht, 2013.
    Published
  59. Rodrigues, J.; Cunha-Oliveira, T.; Ribeiro, M.; Rego, A. C.. "Role of histone deacetylase inhibitors on pyruvate dehydrogenase dysfunction in Huntington's disease striatal cells". Paper presented in Annual Meeting of the European Society for Clinical Investigation, Albufeira, 2013.
    Published
  60. Cunha-Oliveira, T.; Silva, L.; Silva, A. M.; Santos, M. S.; Garrido, J.; Borges, F.; Rego, A. C.; Oliveira, C. R.. "Molecular interaction between cocaine and opioids. Implications on Speedball's toxicity". Paper presented in EuroTox, 2011.
    Published • 10.1016/j.toxlet.2011.05.107
  61. Cunha-Oliveira, T; Rego, AC; Macedo, T; Oliveira, CR. "Changes in the activity of antioxidant enzymes in PC12 cells chronically exposed to psychostimulants". 2007.
    Published
  62. Cunha-Oliveira, Teresa; Rego, A.C.; Macedo, Tice; Oliveira, C.R.. "Adaptation to oxidative stress in the chronic effects of cocaine and amphetamine". 2007.
    Published • 10.1080/10715760701615118
Conference poster
  1. Pinho, Sónia Andreia; Miranda-Santos, Inês; Costa, Cláudio F.; Pinho, Sonia L. C:; Olivia Bagshaw; Valente, Andrew; Stuart, Jeffrey; Oliveira, Paulo J. (E41F-4FB7-5948); Cunha-Oliveira, T.. "Metabolic remodeling upon up-regulation of oxidative phosphorylation in human skin fibroblasts as a tool for personalized medicine". Paper presented in Mitochondrial Medicine (Virtual Conference), 2020.
  2. Silva, Filomena S.G.; Cunha-Oliveira, T.; Silva, Daniela F.; Segura, Luis; Rosenstock, Tatiana; Oliveira, Paulo J. (E41F-4FB7-5948). "Oxidant/antioxidant imbalance in lymphoblasts from amyotrophic lateral sclerosis patients with SOD1 mutations and unknown mutations". Paper presented in Targeting Mitochondria 2020, 2020.
  3. Costa, Cláudio F.; Pinho, Sónia Andreia; Pinho, Sonia L. C:; Oliveira, Paulo J; Cunha-Oliveira, T.. "Molecular and functional characterization of human skin fibroblasts in different metabolic contexts". Paper presented in FEBS 2019 Advanced Course. Oncometabolism: From Conceptual Knowledge to Clinical Applications, Luso, Portugal, 2019.
  4. Ferrão, Rafaela; Pinho, Sonia L. C:; Simões, Rui F.; Lourenço, Nuno; Cunha-Oliveira, T.. "Early mitochondrial changes associated with the toxicity of different drugs of abuse in differentiated SH-SY5Y cells". Paper presented in FEBS 2019 Advanced Course. Oncometabolism: From Conceptual Knowledge to Clinical Applications, 2019.
  5. Pino, Rute; Cunha-Oliveira, T.; Carvalho, Filipa S.; Garcia, Rita; Burgeiro, Ana; Carvalho, Rui; Oliveira, Paulo J.; Lourenço, Nuno. "Unraveling metabolic effects underlying acute cardiotoxicity of the antineoplastic drug Doxorubicin". Paper presented in FEBS 2019 Advanced Course. Oncometabolism: From Conceptual Knowledge to Clinical Applications, Luso, Portugal, 2019.
  6. Silva, Filomena S.G.; Cunha-Oliveira, T.; Bento, Guida; Oliveira, Paulo J.. "Data mining analysis of respiratory and glycolytic fluxes from amyotrophic lateral sclerosis patients: Unraveling the effect of SOD1 mutation.". Paper presented in FEBS 2019 Advanced Course. Oncometabolism: From Conceptual Knowledge to Clinical Applications, Luso, Portugal, 2019.
  7. Simoes, R. F.; Cunha-Oliveira, T.; Oliveira, P. J.; Pereira, F. B.. "Dose-dependent analysis of mitochondrial parameters in differentiated SH-SY5Y cells exposed to mitochondrial toxicants". Paper presented in MitoPorto 2018: Mitochondrial evolution, metabolism and disease, 2018.
  8. Deus, C. M.; Pereira, S. P.; Cunha-Oliveira, T.; Benfeito, S.; Cagide, F.; Borges, F.; Raimundo, N.; Oliveira, P. J.. "Targeting mitochondria with mitochondria-targeted cinnamic antioxidants: a new avenue for sporadic Parkinson’s Disease therapy". Paper presented in MitoPorto 2018: Mitochondrial evolution, metabolism and disease, 2018.
  9. Pereira, S. P.; Cavallaro, C.H.; Grilo, L.; Martins, J.D.; Cardoso, I.; Cunha-Oliveira, T.; Baldeiras, I.; et al. "Being obese during pregnancy: the mitochondrial impact in maternal hepatic tissue". Paper presented in MitoPorto 2018: Mitochondrial evolution, metabolism and disease, 2018.
  10. Costa, C. F.; Pinho, S. L.; Sardao, V. A.; Teixeira, J.; Oliveira, P. J.; Cunha-Oliveira, T.. "Standardization and characterization of cell culture conditions for OXPHOS induction and for mitochondrial health studies in human fibroblasts". Paper presented in MitoPorto 2018: Mitochondrial evolution, metabolism and disease, 2018.
  11. Cardoso, I.; Cunha-Oliveira, T.; Pinho, S. A.; Cavallaro, C.H.; Baldeiras, I.; Pereira, S. P.; Ford, S.; Nathanielsz, P. W.; Oliveira, P. J.. "Remodelling of liver mitochondrial bioenergetics in offspring from obese mothers in a sheep model". Paper presented in MitoPorto 2018: Mitochondrial evolution, metabolism and disease, 2018.
  12. Fonseca, A.C.R.; Burgeiro, A.; Dias, C.; Baldeiras, I.; Cunha-Oliveira, T.; Lourenço, N.; Costa-Nunes, J.; et al. "Mitochondrial function and oxidative stress in epicardial versus subcutaneous adipose tissue from heart failure patients with and without diabetes". Paper presented in MitoPorto 2018: Mitochondrial evolution, metabolism and disease, 2018.
  13. Simoes, R. F.; Cunha-Oliveira, T.; Oliveira, P. J.; Pereira, F. B.. "Optimization of experimental and computational processes to study mitochondrial trafficking and metabolic biomarkers". Paper presented in 52nd Annual Meeting of the European Society for Clinical Investigation, Barcelona, Spain, 2018.
  14. Deus, C. M.; Pereira, S. P.; Cunha-Oliveira, T.; Benfeito, S.; Cagide, F.; Borges, F.; Raimundo, N.; Oliveira, P. J.. "Targeting dietary antioxidants to mitochondria ameliorate metabolic alterations of skin fibroblasts from patients with sporadic Parkinson’s Disease'". Paper presented in 52nd Annual Meeting of the European Society for Clinical Investigation, Barcelona, Spain, 2018.
  15. Pereira, S. P.; Cavallaro, C.H.; Grilo, L.; Martins, J.D.; Cardoso, I.; Baldeiras, I.; Cunha-Oliveira, T.; et al. "Mitochondrial Changes in the Maternal Liver in a Model of Obesity (MO) During Pregnancy". Paper presented in 52nd Annual Meeting of the European Society for Clinical Investigation, Barcelona, Spain, 2018.
  16. Cardoso, I.; Cunha-Oliveira, T.; Pinho, S. A.; Cavallaro, C.H.; Baldeiras, I.; Pereira, S. P.; Ford, S.; Nathanielsz, P. W.; Oliveira, P. J.. "Maternal obesity (MO) in sheep alters offspring mitochondrial hepatic biology and redefines the protein acetylation pattern". Paper presented in 52nd Meeting of the European Society for Clinical Investigation, Barcelona, Spain, 2018.
  17. Deus, C. M.; Pereira, S. P.; Cunha-Oliveira, T.; Benfeito, S.; Cagide, F.; Borges, F.; Raimundo, N.; Oliveira, P. J.. "Mitochondria-directed antioxidants increased metabolic viability of human skin fibroblasts from Parkinson’s disease patients". Paper presented in MuTaLig COST ACTION CA15135; WG meeting 2018, Tenerife, Spain, 2018.
  18. Cardoso, I.; Cunha-Oliveira, T.; Pinho, S.A.; Cavallaro, C.H.; Baldeiras, I.; Pereira, S. P.; Ford, S.; Nathanielsz, P. W.; Oliveira, P. J.. "Impacto da obesidade gestacional na função mitocondrial hepática fetal num modelo ovino". Paper presented in 14º Congresso Português de Diabetes, 2018.
  19. Fonseca, A.C.R.; Burgeiro, A.; Dias, C.; Costa-Nunes, J.; Seraphim, P.; Cunha-Oliveira, T.; Oliveira, P. J.; et al. "O tecido adiposo epicardial é bioenergeticamente mais activo do que o tecido adiposo subcutâneo". Paper presented in 14º Congresso Português de Diabetes, 2018.
  20. Grilo, L.; Pereira, S. P.; Cavallaro, C.H.; Cardoso, I.; Baldeiras, I.; Cunha-Oliveira, T.; Martins, J.D.; et al. "Alterações Mitocondriais no Fígado Materno num Modelo de Obesidade Gestacional". Paper presented in 14º Congresso Português de Diabetes, Algarve, Portugal, 2018.
  21. Cardoso, I.; Cavallaro, C.H.; Pinho, S.; Baldeiras, I.; Pereira, S. P.; Cunha-Oliveira, T.; Smith, A. M.; et al. "Maternal Obesity (MO) in Sheep Leads to Offspring (F1) Lobe-Dependent Impairment of Mitochondrial Hepatic Respiratory Chain Activity and Antioxidant Enzyme Activity". Paper presented in SRI 65th Annual Scientific Meeting, San Diego, CA, USA, 2018.
  22. Pereira, S. P.; Cavallaro, C.H.; Grilo, L.; Cardoso, I.; Baldeiras, I.; Cunha-Oliveira, T.; Smith, A. M.; et al. "Maternal Nutrient Excess and Obesity (MO) in Ewes during Pregnancy Leads to Alterations in Hepatic Mitochondrial Biology and Redox Balance". Paper presented in SRI 65th Annual Scientific Meeting, San Diego, CA, USA, 2018.
  23. Naia, L.; Cunha-Oliveira, T.; Rodrigues, J.; Rosenstock, T.; Oliveira, A.; Ribeiro, M.; Carmo, C.; et al. "Activation of pyruvate dehydrogenase complex by sodium butyrate ameliorates mitochondrial and motor phenotype in Huntington’s disease models". Paper presented in Mitoporto 2017– Advances in mitochondrial research, 2017.
  24. Serafim, T. L.; Deus, C. M.; Cunha-Oliveira, T.; Sardao, V. A.; Cunha, P.; Veloso, C.; Costa, D.; et al. "Stimulation of mitochondrial metabolism in human breast cancer cells results in increased cell motility and decreased resistance to metabolic inhibitors". Paper presented in Mitoporto 2017– Advances in mitochondrial research, 2017.
  25. Cunha-Oliveira, T.; Coelho, A. R.; Deus, C. M.; Oliveira, P. J.. "Mitochondrial dysfunction and p53 signaling in mouse stem cell-derived cardiomyocytes treated with doxorubicin". Paper presented in Mitoporto 2017– Advances in mitochondrial research, 2017.
    10.1109/ultsym.2017.8091621
  26. Serafim, T. L.; Cunha-Oliveira, T.; Deus, C. M.; Cardoso, I.; Pinho, S.A.; Yang, S.; Tuerxun, A.; et al. "Decreased Fetal Hepatic Mitochondrial Respiratory Chain Activity caused by Maternal Obesity in Sheep". Paper presented in Mitoporto 2017– Advances in mitochondrial research, 2017.
  27. Serafim, T. L.; Deus, C. M.; Pinho, S. A.; Martins, T. R.; Sardao, V. A.; Grilo, L.; Cavallaro, C.H.; et al. "Impact of Maternal Obesity During Pregnancy on Fetal Hepatic Redox Profile and Quality Control Proteins". Paper presented in Mitoporto 2017– Advances in mitochondrial research, 2017.
  28. Campos, J.; Pereira, F. B.; Costa, E.; Sardao, V. A.; Cunha-Oliveira, T.; Silva, T. B.; Simoes, R. F.; et al. "Extracting Knowledge from Data to Predict Mitochondrial Toxicity Indexes for Pharmacological Compounds". Paper presented in Mitoporto 2017– Advances in mitochondrial research, 2017.
  29. Ferreira, L. L.; Cunha-Oliveira, T.; Costa, C. F.; Oliveira, P. J.. "Protective effect of subcytotoxic doxorubicin preconditioning on H9c2 heart-derived cells viability through mitochondrial compensatory responses". Paper presented in Mitoporto 2017– Advances in mitochondrial research, 2017.
  30. Pereira, S. P.; Nijland, M. J.; Tavares, L. C.; Duarte, A. I.; Baldeiras, I.; Cunha-Oliveira, T.; Santos, M. S.; et al. "Effects of Moderate Global Maternal Nutrient Reduction on Fetal Baboon Cardiac Left Ventricular Mitochondria". Paper presented in Mitoporto 2017– Advances in mitochondrial research, 2017.
  31. Costa, C. F.; Maleita, J.; Deus, C. M.; Pereira, S. P.; Serafim, T. L.; Sardao, V. A.; Oliveira, P. J.; Cunha-Oliveira, T.. "Characterization of mitochondrial parameters in cell lines in the presence or absence of glucose". Paper presented in Mitoporto 2017– Advances in mitochondrial research, 2017.
  32. Pereira, S. P.; Tavares, L. C.; Duarte, A. I.; Cunha-Oliveira, T.; Santos, M. S.; Baldeiras, I.; Clarke, G.; et al. "Influence of Maternal Nutrition During Pregnancy on Fetal Cardiac Mitochondria Outcome". Paper presented in XIX Meeting of the Portuguese Biochemical Society, 2016.
  33. Ferreira, A. M.; Simoes, R. F.; Vilaca, A.; Carvalho, F. S.; Garcia, R.; Burgeiro, A.; Cunha-Oliveira, T.; et al. "Decreased global DNA methylation levels and gene expression patterns related metabolic end epigenetic remodeling enzymes are observed after Doxorubicin sub-chronic treatment". Paper presented in 50th Annual Meeting of the European Society for Clinical Investigation, Paris, France, 2016.
  34. Pereira, S. P.; Serafim, T. L.; Cunha-Oliveira, T.; Deus, C. M.; Starostina, I. G.; Ivanova, V. V.; Rizvanov, A. A.; Oliveira, P. J.. "Metabolic remodeling of human skin fibroblasts as model for studying mitochondrial diseases and drug-induced toxicity". Paper presented in 50th Meeting of the European Society for Clinical Investigation, Paris, France, 2016.
  35. Machado, N. G.; Cunha-Oliveira, T.; Burgeiro, A.; Oliveira, P. J.. "Influence of Exogenous Lactate on H9c2 Cardiomyoblast Gene Expression and Proliferation". Paper presented in Cancer Epigenetics and Metabolism: Connecting the Dots, 2015.
  36. Ferreira, A. M.; Vilaca, A.; Carvalho, F. S.; Garcia, R.; Burgeiro, A.; Cunha-Oliveira, T.; Oliveira, P. J.. "Doxorubicin decreases global DNA methylation levels, depletes mtDNA and causes down-regulation of transcripts for metabolic end epigenetic remodeling enzymes". Paper presented in Cancer Epigenetics and Metabolism: Connecting the Dots, 2015.
  37. Serafim, T. L.; Cunha-Oliveira, T.; Sardao, V. A.; Deus, C. M.; Greene, A.; Perkins, E.; Oliveira, P. J.. "Characterization of mitochondria of breast cancer cell lines". Paper presented in XVIII Congress of the Portuguese Biochemical Society, 2014.
  38. Martins, T. R.; Deus, C. M.; Cunha-Oliveira, T.; Oliveira, P. J.. "Berberine modulates DOX-induced cell death and autophagy in rat cardiomyoblasts". Paper presented in XVIII Congress of the Portuguese Biochemical Society, 2014.
  39. Ferreira, L. L.; Cunha-Oliveira, T.; Oliveira, P. J.. "Doxorubicin persistently alters mitochondrial gene expression in H9c2 cells". Paper presented in XVIII Congress of the Portuguese Biochemical Society, 2014.
  40. Machado, N. G.; Cunha-Oliveira, T.; Burgeiro, A.; Oliveira, P. J.. "Role of Exogenous Lactate on H9c2 Cardiomyoblast Gene Expression and Proliferation". Paper presented in XVIII Congress of the Portuguese Biochemical Society, 2014.
  41. Cunha-Oliveira, T.; Martins, T. R.; Moreira, A. C.; Branco, A. F.; Sampaio, S. F.; Holy, J.; Oliveira, P. J.; Sardao, V. A.. "Cathepsin B Activation And Apoptosis-Inducing Factor Translocation Mediate Doxorubicin-Induced Toxicity On H9c2 Cardiomyoblasts". Paper presented in XVIII Congress of the Portuguese Biochemical Society, 2014.
  42. Cunha-Oliveira, T.; Martins, T. R.; Moreira, A. C.; Branco, A. F.; Sampaio, S. F.; Holy, J.; Oliveira, P. J.; Sardao, V. A.. "Involvement of Cathepsin B and Mitochondrial Apoptosis-Inducing Factor on Doxorubicin Cardiotoxicity". Paper presented in 5th World Congress on Targeting Mitochondria, Berlin, Germany, 2014.
  43. Cunha-Oliveira, T.; Vega-Naredo, I.; Sardao, V. A.; Oliveira, P. J.. "Predicting Mitochondrial Liabilities During Drug Discovery and Development". Paper presented in Showcasing Portuguese Pharma Science: Advances in Discovery, Development and Manufacturing, 2014.
  44. Naia, L.; Ferreira, I. L.; Cunha-Oliveira, T.; Ribeiro, M.; Duarte Ana I.; Ribeiro, M.J.; Oliveira, Catarina R; et al. "Activation of IR,IGF-1R signaling pathways promote mitochondrial function and energy metabolism in Huntington’s disease human lymphoblasts". 2013.
  45. Cunha-Oliveira, T.; Silva, Lisbeth; Silva, Ana Maria; Moreno, António J; Oliveira, C.R.; Santos, Maria S.; Cunha-Oliveira, Teresa; Moreno, António J.; Oliveira, Catarina R.. "Mitochondrial complex I dysfunction induced by cocaine and cocaine plus morphine in brain and liver mitochondria". 2013.
  46. Cunha-Oliveira, T.; Naia, L.; Ferreira, I. L.; Rosenstock, T.; Duarte, A. I.; Ribeiro, M.; Laço, M.; et al. "Activation of IGF-1 and insulin signaling pathways ameliorate energy metabolism and mitochondrial function in Huntington’s disease human lymphoblasts". Paper presented in Neuroscience 2012: Annual Meeting of the Society for Neuroscience, New Orleans, LA, USA, 2012.
  47. Rosenstock, T.; Rodrigues, J.; Naia, L.; Cunha-Oliveira, T.; Rego, A. C.. "Regulation of pyruvate dehydrogenase and mitochondrial function by histone deacetylase inhibitors". Paper presented in Neuroscience 2012: Annual Meeting of the Society for Neuroscience, New Orleans, LA, USA, 2012.
  48. Cunha-Oliveira, T.; Viana, S.; Travassos, A.S.; Nunes, S.; Silva, C.; Rego, A. C.; Ali, S.F.; Fontes-Ribeiro, C.; Pereira, F. C.. "Acute methamphetamine intoxication evokes deregulation of striatal glutamatergic/gabaergic homeostasis in mice". Paper presented in 8th FENS Forum, Barcelona, Spain, 2012.
  49. Rosenstock, T.; Rodrigues, J.; Naia, L.; Cunha-Oliveira, T.; Rego, A. C.. "Impact of histone deacetylase inhibitors on pyruvate dehydrogenase and mitochondrial function in cellular models of Huntington's disease". Paper presented in 8th FENS Forum, Barcelona, Spain, 2012.
  50. Rodrigues, J.; Rosenstock, T.; Ribeiro, M.; Ferreira, I. L.; Cunha-Oliveira, T.; Rego, A.C.. "Regulation of pyruvate dehydrogenase by histone deacetylase inhibitors in Huntington’s disease striatal cells". Paper presented in 26th Meeting of the "Grupo de Estudos em Envelhecimento Cerebral e Demência", 2012.
  51. Naia, L.; Rodrigues, J.; Ribeiro, M.; Duarte, A. I.; Cunha-Oliveira, T.; Hayden, M. R.; Rego, A. C.. "Role of Insulin and IGF-1 on Glucose Metabolism in Striatal and Cortical Models of Huntington’s Disease". Paper presented in SINAL 2012 - 6th National Meeting on Cell Signaling, 2012.
  52. Rodrigues, J.; Ribeiro, M.; Cunha-Oliveira, T.; Oliveira, C.R.; Rego, A.C.. "Insulin and IGF-1 effects in energy metabolism parameters in Huntington’s disease knock-in striatal cells". 2012.
  53. Naia, L.; Ferreira, L. L.; Cunha-Oliveira, T.; Ribeiro, M.; Duarte, A. I.; Ribeiro, M. J.; Oliveira, C. R.; Rego, A. C.. "Activation of IGF-1 and insulin signaling pathways ameliorate mitochondrial function and energy metabolism in Huntington’s disease human lymphoblasts". Paper presented in Encontro da Faculdade de Medicina, 2011.
  54. Pereira, F. C.; Nunes, S.; Cunha-Oliveira, T.; Viana, S.; Silva, C.; Silva, A. M.; Travassos, A. S.; et al. "Time-Dependent Effects of Methamphetamine on Striatal Neurochemical and Astrocytic Profile and Motor Coordination in Mice". Paper presented in 3rd IDARS/ISN/ESN Satellite Meeting, 2011.
  55. Ferreira, I. L.; Cunha-Oliveira, T.; Ribeiro, M.; Nascimento, M. V.; Proença, M. T.; Januário, C.; Oliveira, C. R.; et al. "Bioenergetic dysfunction in Huntington's Disease human cybrids". Paper presented in XII Meeting of the Portuguese Neuroscience Society, 2011.
    10.1016/j.expneurol.2011.05.024
  56. Laço, M.; Ferreira, I. L.; Cunha-Oliveira, T.; Ribeiro, M.; Rosenstock, T.; Naia, L.; Ribeiro, M. J.; Oliveira, C. R.; Rego, A. C.. "IGF-1 recovers mitochondrial function in Huntington’s disease human lymphoblasts". Paper presented in SINAL 2011 5th Annual Meeting on Cell Signaling, 2011.
  57. Cunha-Oliveira, T.; Ferreira, I. L.; Nascimento, M. V.; Ribeiro, M.; Proença, T.; Januário, C.; Oliveira, C.R.; Rego, A.C.. "Impairment of energy metabolism in Huntington's Disease human cybrids". 2011.
  58. Pereira, F.C.; Viana, S.; Nunes, S.; Cunha-Oliveira, T.; Travassos, A.S.; Silva, C.; Silva, A.M.; et al. "Effect of a single high-dose of methamphetamine on striatal alpha-synuclein, RAGE, neurochemical levels and motor coordination in mice". 2011.
  59. Cunha-Oliveira, T.; Rego, A.C.; Garrido, J.; Borges, F.; Macedo, T.; Oliveira, C.R.. "Neurotoxicity of sequential and simultaneous exposure to heroin and cocaine in rat cortical neurons". 2010.
  60. Nunes, S.; Cunha-Oliveira, T.; Silva, C.; Silva, A.M.; Adrião, M.; Travassos, A.S.; Fontes-Ribeiro, C.; Reis, F.; Pereira, F.C.. "Time-dependent neurochemical and motor coordination profile of methamphetamine exposed mice". 2010.
  61. Cunha-Oliveira, T.; Rego, A.C.; Garrido, J.; Borges, F.; Macedo, T.; Oliveira, C.R.. "Neurotoxicity of cocaine-opioid combinations in rat cortical neurons". 2009.
  62. Cunha-Oliveira, T.; Marques, M.P.; Costa, R.P.; Garrido, J.; Borges, F.; Macedo, T.; Rego, A.C.; Oliveira, C.R.. "Chemistry and neurotoxicity of cocaine-opioid adducts". 2008.
  63. Cunha-Oliveira, T.; Murteira, E.; Garrido, J.; Borges, F.; Rego, A.C.; Oliveira, C.R.. "Neurotoxicity of cocaine-opioid adducts". 2008.
  64. Cunha-Oliveira, T.; Rego, A.C.; Macedo, T.; Oliveira, C.R.. "Adaptation to oxidative stress in the chronic effects of cocaine and amphetamine (P027)". 2007.
  65. Cunha-Oliveira, T.; Rego, A.C.; Macedo, T.; Oliveira, C.R.. "Changes in toxicity in PC12 cells chronically exposed to opioid and stimulant drugs of abuse and hydrogen peroxide". Paper presented in Neuroscience 2006: 36th Annual Meeting of the Society for Neuroscience, Atlanta, Georgia, USA, 2006.
  66. Cunha-Oliveira, T.; Rego, A.C.; Macedo, T.; Oliveira, C.R.. "Neurotoxicity of cocaine, amphetamine and heroin". Paper presented in Neurobiology and drug abuse - 2nd Symposium, 2006.
  67. Cunha-Oliveira, T.; Rego, A.C.; Garrido, J.; Borges, F.; Macedo, T.; Oliveira, C.R.. "Street heroin induces mitochondrial dysfunction and apoptosis in rat cortical neurons". Paper presented in IV Annual Meeting of the Center for Neuroscience and Cell Biology, 2006.
  68. Nascimento, M. V.; Ribeiro, M.; Ferreira, I. L.; Almeida, S.; Cunha-Oliveira, T.; Cardoso, S. M.; Januário, C.; et al. "Evidence for oxidative stress and increased susceptibility to apoptotic inducers in Huntington's disease cybrids and striatal cells". Paper presented in XV National Congress of Biochemistry, 2006.
  69. Cunha-Oliveira, T.; Rego, A. C.; Macedo, T.; Oliveira, C. R.. "Heroin induces mitochondrial dysfunction in rat cortical neurons". Paper presented in III Annual Meeting of the Center for Neurosciences and Cell Biology, 2005.
  70. Cunha-Oliveira, T.; Rego, A.C.; Macedo, T.; Oliveira, C.R.. "Heroin-induced degeneration of cortical neurons involves mitochondria-dependent apoptosis". Paper presented in Neuroscience 2005: 35th Annual Meeting of the Society for Neuroscience, Washington DC, USA, 2005.
  71. Cunha-Oliveira, T.; Rego, A.C.; Macedo, T.; Oliveira, C.R.. "Role of mitochondria in heroin-induced neurodegeneration". Paper presented in FEBS-IUBMB Workshop on: "Mitochondrial dynamics in cell life and death", Padova, Italy, 2005.
  72. Domingues, A.; Cunha-Oliveira, T.; Macedo, T.; Oliveira, C.R.; Rego, A.C.. "Expression of NR1/NR2B N-methyl-D-Aspartate receptors enhance heroin toxicity in HEK293 cells". Paper presented in Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Cocaine, GHB and Substituted Amphetamines, Venice, Italy, 2005.
  73. Cunha-Oliveira, T.; Rego, A.C.; Morgadinho, M.T.; Sarmento, A.; Macedo, T.; Oliveira, C.R.. "Differential cytotoxic responses of PC12 cells chronically exposed to psychostimulants or hydrogen peroxide". Paper presented in 8th Meeting of the Portuguese Neuroscience Society, 2005.
  74. Cunha-Oliveira, T.; Rego, A.C.; Macedo, T.; Oliveira, C.R.. "Involvement of oxidative stress in the neurotoxicity of drugs of abuse". Paper presented in FEBS workshop on "Free radicals and diseases: gene expression, cellular metabolism and pathophysiology", Spetses, Greece, 2004.
  75. Cunha-Oliveira, T.; Rego, A.C.; Macedo, T.; Oliveira, C.R.. "Heroin neurotoxicity is mediated by the mitochondrial apoptotic pathway". Paper presented in FEBS course on "New molecular strategies to treat neurodegenerative diseases", 2004.
  76. Cunha-Oliveira, T.; Rego, A.C.; Macedo, T.; Oliveira, C.R.. "Heroin neurotoxicity involves apoptosis and increased reactive oxygen species in rat cortical neurons". Paper presented in 4th FENS Forum, 2004.
  77. Cunha-Oliveira, T.; Rego, A.C.; Morgadinho, M.T.; Sarmento, A.; Macedo, T.; Oliveira, C.R.. "Chronic and acute effects of heroin, cocaine and amphetamine in PC12 cells". Paper presented in 1st Symposium of the International Institute of Neuroscience of Natal, Brazil, 2004.
  78. Cunha-Oliveira, T.; Rego, A.C.; Macedo, T.; Oliveira, C.R.. "Changes in Bcl-2 levels are involved in heroin-induced neuronal apoptosis". Paper presented in XIV Portuguese Biochemistry Congress, 2004.
  79. Cunha-Oliveira, T.; Rego, A.C.; Macedo, T.; Oliveira, C.R.. "Neurotoxicidade induzida pela heroína- Envolvimento da via apoptótica mitocondrial". Paper presented in IV Congresso de Investigação em Medicina, 2004.
  80. Cunha-Oliveira, T.; Rego, A.C.; Macedo, T.; Oliveira, C.R.. "Neurotoxic effects of heroin are mediated by reactive oxygen species". Paper presented in 6th Portuguese Congress on Free Radicals in Chemistry, Biology and Medicine; 1st Luso-Spanish Congress on Free Radicals, 2003.
  81. Cunha-Oliveira, T.; Rego, A.C.; Macedo, T.; Oliveira, C.R.. "Apoptotic events involved in the neurotoxicity of drugs of abuse". Paper presented in Apoptosis 2003: From signaling pathways to therapeutic tools, Luxembourg, 2003.
  82. Cunha-Oliveira, T.; Rego, A.C.; Morgadinho, M.T.; Sarmento, A.; Macedo, T.; Oliveira, C.R.. "Effect of chronic and acute administration of drugs of abuse to PC12 cells". Paper presented in 17º Encontro do Grupo de Estudos de Envelhecimento Cerebral e Demência, 2003.
  83. Cunha-Oliveira, T.; Rego, A.C.; Macedo, T.; Oliveira, C.R.. "Mitochondrial dysfunction and caspases activation in the neurotoxicity induced by heroin, amphetamine or cocaine in cortical cultures". Paper presented in 8th Meeting of the Portuguese Society of Neurosciences, 2003.
  84. Rego, A.C.; Cunha-Oliveira, T.; Macedo, T.; Oliveira, C.R.. "Involvement of mitochondrial apoptotic pathway in PC12 cell death induced by heroin, amphetamine and cocaine". Paper presented in 3rd FENS Forum of European Neuroscience, Paris, France, 2002.
  85. Cunha-Oliveira, T.; Rego, A.C.; Macedo, T.; Oliveira, C.R.. "Role of reactive oxygen species in the mechanisms of cell injury induced by cocaine, heroin and amphetamine". Paper presented in International Symposium on "Reactive oxygen and nitrogen species: diagnostic, preventive and therapeutic values", St Petersburg, Russia, 2002.
  86. Cunha-Oliveira, T.; Rego, A.C.; Macedo, T.; Oliveira, C.R.. "Apoptotic cell death induced by drugs of abuse in rat cortical neurons". Paper presented in XIII Congresso de Bioquímica, 2002.
  87. Cunha-Oliveira, T.; Rego, A.C.; Morgadinho, M.T.; Macedo, T.; Oliveira, C.R.. "Oxidative injury induced by drugs of abuse". Paper presented in III Congress on Medical Research, 2002.
  88. Cunha-Oliveira, T.; Rego, A.C.; Macedo, T.; Oliveira, C.R.. "Differential activation of caspases in the neuronal cell death induced by drugs of abuse". Paper presented in 16º Encontro do Grupo de Estudos de Envelhecimento Cerebral e Demência, 2002.
  89. Cunha-Oliveira, T.; Rego, A.C.; Macedo, T.; Oliveira, C.R.. "Drugs of abuse-induced cell death in PC12 cells". Paper presented in FEBS course on: "Mitochondrial in the cell life and death", Moscow, Russia, 2001.
  90. Cunha-Oliveira, T.; Rego, A.C.; Macedo, T.; Oliveira, C.R.. "Toxic effects of opioid and stimulant drugs on undifferentiated PC12 cells". Paper presented in Satellite Meeting of the International Society for Neurochemistry and American Society for Neurochemistry, Mar del Plata, Argentina, 2001.
  91. Cunha-Oliveira, T.; Rego, A.C.; Morgadinho, M.T.; Macedo, T.; Oliveira, C.R.. "Cell death induced by cocaine, amphetamine and heroin is associated with changes in intracellular dopamine". Paper presented in 7th Meeting of the Portuguese Neuroscience Society, 2001.
Journal article
  1. Sónia A. Pinho; Paulo J. Oliveira; Teresa Cunha-Oliveira. "Heterogeneous redox responses in NHDF cells primed to enhance mitochondrial bioenergetics". Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease (2025): https://doi.org/10.1016/j.bbadis.2024.167495.
    10.1016/j.bbadis.2024.167495
  2. Cunha-Oliveira, T.; Ioannidis, John P.A.; Oliveira, Paulo J.. "Best Practices for Data Management and Sharing in Experimental Biomedical Research". Physiological Reviews (2024): http://dx.doi.org/10.1152/physrev.00043.2023.
    Open access • In press • 10.1152/physrev.00043.2023
  3. Teresa Cunha-Oliveira; Liliana Montezinho; Rui F. Simões; Marcelo Carvalho; Elisabete Ferreiro; Filomena S. G. Silva. "Mitochondria: A Promising Convergent Target for the Treatment of Amyotrophic Lateral Sclerosis". Cells (2024): https://doi.org/10.3390/cells13030248.
    10.3390/cells13030248
  4. Susana P. Pereira; Mariana S. Diniz; Ludgero C. Tavares; Teresa Cunha-Oliveira; Cun Li; Laura A. Cox; Mark J. Nijland; Peter W. Nathanielsz; Paulo J. Oliveira. "Characterizing Early Cardiac Metabolic Programming via 30% Maternal Nutrient Reduction during Fetal Development in a Non-Human Primate Model". International Journal of Molecular Sciences (2023): https://doi.org/10.3390/ijms242015192.
    10.3390/ijms242015192
  5. Pinho, S.A.; Anjo, S.I.; Cunha-Oliveira, T.. "Metabolic Priming as a Tool in Redox and Mitochondrial Theragnostics". Antioxidants (2023): https://www.mdpi.com/2076-3921/12/5/1072.
    Open access • Published • 10.3390/antiox12051072
  6. Amorim, Ricardo; Simões, Inês C.M.; Teixeira, José; Cagide, Fernando; Potes, Yaiza; Soares, Pedro; Carvalho, Adriana; et al. "Mitochondria-targeted anti-oxidant AntiOxCIN4 improved liver steatosis in Western diet-fed mice by preventing lipid accumulation due to upregulation of fatty acid oxidation, quality control mechanism and antioxidant defense systems". Redox Biology 55 (2022): 102400. http://dx.doi.org/10.1016/j.redox.2022.102400.
    Published • 10.1016/j.redox.2022.102400
  7. Cunha-Oliveira, Teresa; Carvalho, Marcelo; Sardão, Vilma; Ferreiro, Elisabete; Mena, Débora; Pereira, Francisco B.; Borges, Fernanda; Oliveira, Paulo J.; Silva, Filomena S. G.. "Integrative Profiling of Amyotrophic Lateral Sclerosis Lymphoblasts Identifies Unique Metabolic and Mitochondrial Disease Fingerprints". Molecular Neurobiology 59 10 (2022): 6373-6396. http://dx.doi.org/10.1007/s12035-022-02980-7.
    Published • 10.1007/s12035-022-02980-7
  8. Panieri, Emiliano; Pinho, Sónia A.; Afonso, Gonçalo J. M.; Oliveira, Paulo J.; Cunha-Oliveira, T.; Saso, Luciano. "NRF2 and Mitochondrial Function in Cancer and Cancer Stem Cells". Cells 11 15 (2022): 2401. http://dx.doi.org/10.3390/cells11152401.
    Open access • Published • 10.3390/cells11152401
  9. Cunha-Oliveira, T.; Silva, Daniela Franco; Segura, Luis; Baldeiras, Inês; Marques, Ricardo; Rosenstock, Tatiana; Oliveira, Paulo J.; Silva, Filomena S. G.. "Redox profiles of amyotrophic lateral sclerosis lymphoblasts with or without known SOD1 mutations". European Journal of Clinical Investigation 52 9 (2022): http://dx.doi.org/10.1111/eci.13798.
    Published • 10.1111/eci.13798
  10. Rui F. Simões; Paulo J. Oliveira; Teresa Cunha-Oliveira; Francisco B. Pereira. "Evaluation of 6-Hydroxydopamine and Rotenone In Vitro Neurotoxicity on Differentiated SH-SY5Y Cells Using Applied Computational Statistics". International Journal of Molecular Sciences 23 6 (2022): 3009-3009. https://doi.org/10.3390/ijms23063009.
    10.3390/ijms23063009
  11. Pinho, Sónia A.; Costa, Cláudio F.; Deus, Cláudia M.; Pinho, Sonia L.C.; Miranda-Santos, Inês; Afonso, Gonçalo; Bagshaw, Olivia; et al. "Mitochondrial and metabolic remodeling in human skin fibroblasts in response to glucose availability". The FEBS Journal (2022): http://dx.doi.org/10.1111/febs.16413.
    Published • 10.1111/febs.16413
  12. Cunha-Oliveira, T.; Carvalho, Marcelo; Sardão, V.; Ferreiro, Elisabete; Mena, D.; Francisco B Pereira ; Borges, Fernanda; Oliveira, P.J.; Silva, Filomena. Corresponding author: Cunha-Oliveira, T.. "Integrative Profiling of Amyotrophic Lateral Sclerosis Lymphoblasts Identifies Unique Metabolic and Mitochondrial Disease Fingerprints". Research Square (2022): https://www.researchsquare.com/article/rs-1196454/v1.
    Open access • Under revision • 10.21203/rs.3.rs-1196454/v1
  13. Rui F. Simões; Rute Pino; Maurício Moreira-Soares; Jaromira Kovarova; Jiri Neuzil; Rui Travasso; Paulo J. Oliveira; Teresa Cunha-Oliveira; Francisco B. Pereira. "Quantitative analysis of neuronal mitochondrial movement reveals patterns resulting from neurotoxicity of rotenone and 6-hydroxydopamine". The FASEB Journal 35 12 (2021): https://doi.org/10.1096/fj.202100899R.
    10.1096/fj.202100899R
  14. Deus, Cláudia M.; Pereira, Susana P.; Cunha-Oliveira, Teresa; Teixeira, José; Simões, Rui F.; Cagide, Fernando; Benfeito, Sofia; et al. "A mitochondria-targeted caffeic acid derivative reverts cellular and mitochondrial defects in human skin fibroblasts from male sporadic Parkinson's disease patients". Redox Biology (2021): 102037. http://dx.doi.org/10.1016/j.redox.2021.102037.
    Open access • Published • 10.1016/j.redox.2021.102037
  15. Pereira, Susana P.; Tavares, Ludgero C.; Duarte, Ana I.; Baldeiras, Inês; Cunha-Oliveira, Teresa; Martins, João D.; Santos, Maria S.; et al. "Sex-dependent vulnerability of fetal nonhuman primate cardiac mitochondria to moderate maternal nutrient reduction". Clinical Science 135 9 (2021): 1103-1126. http://dx.doi.org/10.1042/cs20201339.
    Published • 10.1042/cs20201339
  16. Simões, Rui F.; Ferrão, Rafaela; Silva, Margarida R.; Pinho, Sonia L. C.; Ferreira, Lino; Oliveira, Paulo J.; # Cunha-Oliveira, T.. Corresponding author: # Cunha-Oliveira, T.. "Refinement of a differentiation protocol using neuroblastoma SH-SY5Y cells for use in neurotoxicology research". Food and Chemical Toxicology (2021): 111967. https://doi.org/10.1016/j.fct.2021.111967.
    Published • 10.1016/j.fct.2021.111967
  17. Jacinto, Sandra; Guerreiro. Patrícia; Machado de Oliveira, Rita; Cunha-Oliveira, T.; Santos, Maria João; Grazina, Manuela; Rego, Ana Cristina; Outeiro, Tiago. "MPV17 mutations are associated with a quiescent energetic metabolic profile". Frontiers in Cellular Neuroscience (2021): https://www.frontiersin.org/articles/10.3389/fncel.2021.641264/abstract.
    Published
  18. Costa, C. F.; Pinho, S.A.; Pinho, S. L.; Miranda-Santos, I.; Bagshaw, O.; Stuart, J.; Oliveira, P.J.; # Cunha-Oliveira, T.. Corresponding author: # Cunha-Oliveira, T.. "Mitochondrial and metabolic remodeling in human skin fibroblasts in response to glucose availability". BioRxiv (2021): https://www.biorxiv.org/content/10.1101/2021.02.24.432508v1.
    Open access • Published • 10.1101/2021.02.24.432508
  19. Cunha-Oliveira, Teresa; Montezinho, Liliana; Mendes, Catarina; Firuzi, Omidreza; Saso, Luciano; Oliveira, Paulo J.; Silva, Filomena S. G.. "Oxidative Stress in Amyotrophic Lateral Sclerosis: Pathophysiology and Opportunities for Pharmacological Intervention". Oxidative Medicine and Cellular Longevity 2020 (2020): 1-29. http://dx.doi.org/10.1155/2020/5021694.
    Published • 10.1155/2020/5021694
  20. Serafim, Teresa L.; * Cunha-Oliveira, Teresa; Deus, Claudia M.; Sardão, Vilma A.; Cardoso, Ines M.; Yang, Shanshan; Odhiambo, John F.; et al. "Maternal obesity in sheep impairs foetal hepatic mitochondrial respiratory chain capacity". European Journal of Clinical Investigation 51 2 (2020): http://dx.doi.org/10.1111/eci.13375.
    Published • 10.1111/eci.13375
  21. Deus, Cláudia M.; Pereira, Susana P.; Cunha-Oliveira, Teresa; Pereira, Francisco B.; Raimundo, Nuno; Oliveira, Paulo J.. "Mitochondrial remodeling in human skin fibroblasts from sporadic male Parkinson's disease patients uncovers metabolic and mitochondrial bioenergetic defects". Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1866 3 (2020): 165615. http://dx.doi.org/10.1016/j.bbadis.2019.165615.
    Published • 10.1016/j.bbadis.2019.165615
  22. Ferreira, Luciana L.; Cervantes, Marlene; Froufe, Hugo J. C.; Egas, Conceição; Cunha-Oliveira, Teresa; Sassone-Corsi, Paolo; Oliveira, Paulo J.. "Doxorubicin persistently rewires cardiac circadian homeostasis in mice". Archives of Toxicology (2019): http://dx.doi.org/10.1007/s00204-019-02626-z.
    Published • 10.1007/s00204-019-02626-z
  23. Ferreira, Leonardo M. R.; Cunha-Oliveira, Teresa; Sobral, Margarida C.; Abreu, Patrícia L.; Alpoim, Maria Carmen; Urbano, Ana M.. "Impact of Carcinogenic Chromium on the Cellular Response to Proteotoxic Stress". International Journal of Molecular Sciences 20 19 (2019): 4901. http://dx.doi.org/10.3390/ijms20194901.
    Published • 10.3390/ijms20194901
  24. Valdinocci, Dario; Simões, Rui F.; Kovarova, Jaromira; Cunha-Oliveira, Teresa; Neuzil, Jiri; Pountney, Dean L.. "Intracellular and Intercellular Mitochondrial Dynamics in Parkinson's Disease". Frontiers in Neuroscience 13 (2019): http://dx.doi.org/10.3389/fnins.2019.00930.
    Open access • 10.3389/fnins.2019.00930
  25. Bajzikova, Martina; Kovarova, Jaromira; Coelho, Ana R.; Boukalova, Stepana; Oh, Sehyun; Rohlenova, Katerina; Svec, David; et al. "Reactivation of Dihydroorotate Dehydrogenase-Driven Pyrimidine Biosynthesis Restores Tumor Growth of Respiration-Deficient Cancer Cells". Cell Metabolism 29 2 (2019): 399-416.e10. http://dx.doi.org/10.1016/j.cmet.2018.10.014.
    Published • 10.1016/j.cmet.2018.10.014
  26. Ferreira, Luciana L.; Cunha-Oliveira, Teresa; Veloso, Caroline D.; Costa, Cláudio F.; Wallace, Kendall B.; Oliveira, Paulo J.. "Single nanomolar doxorubicin exposure triggers compensatory mitochondrial responses in H9c2 cardiomyoblasts". Food and Chemical Toxicology 124 (2019): 450-461. http://dx.doi.org/10.1016/j.fct.2018.12.017.
    Published • 10.1016/j.fct.2018.12.017
  27. # Teresa Cunha-Oliveira; Luciana L. Ferreira; Ana Raquel Coelho; Cláudia M. Deus; Paulo J. Oliveira. Corresponding author: # Teresa Cunha-Oliveira. "Doxorubicin triggers bioenergetic failure and p53 activation in mouse stem cell-derived cardiomyocytes". Toxicology and Applied Pharmacology 348 (2018): 1-13. https://doi.org/10.1016/j.taap.2018.04.009.
    Published • 10.1016/j.taap.2018.04.009
  28. Pereira, Susana P; Deus, Cláudia M; Serafim, Teresa L; Cunha-Oliveira, Teresa; Oliveira, Paulo J. "Metabolic and Phenotypic Characterization of Human Skin Fibroblasts After Forcing Oxidative Capacity". Toxicological Sciences 164 1 (2018): 191-204. http://dx.doi.org/10.1093/toxsci/kfy068.
    Published • 10.1093/toxsci/kfy068
  29. Abreu, Patrícia L.; Cunha-Oliveira, Teresa; Ferreira, Leonardo M. R.; Urbano, Ana M.. "Hexavalent chromium, a lung carcinogen, confers resistance to thermal stress and interferes with heat shock protein expression in human bronchial epithelial cells". BioMetals 31 4 (2018): 477-487. http://dx.doi.org/10.1007/s10534-018-0093-7.
    Published • 10.1007/s10534-018-0093-7
  30. Ferreira, André; * Cunha-Oliveira, Teresa; Simões, Rui F.; Carvalho, Filipa S.; Burgeiro, Ana; Nordgren, Kendra; Wallace, Kendall B.; Oliveira, Paulo J.. "Altered mitochondrial epigenetics associated with subchronic doxorubicin cardiotoxicity". Toxicology 390 (2017): 63-73. http://dx.doi.org/10.1016/j.tox.2017.08.011.
    Open access • Published • 10.1016/j.tox.2017.08.011
  31. Naia, Luana; * Cunha-Oliveira, Teresa; Rodrigues, Joana; Rosenstock, Tatiana R.; Oliveira, Ana; Ribeiro, Márcio; Carmo, Catarina; et al. "Histone Deacetylase Inhibitors Protect Against Pyruvate Dehydrogenase Dysfunction in Huntington's Disease". The Journal of Neuroscience 37 10 (2017): 2776-2794. http://dx.doi.org/10.1523/jneurosci.2006-14.2016.
    Published • 10.1523/JNEUROSCI.2006-14.2016
  32. Coelho, Ana R.; Martins, Tatiana R.; Couto, Renata; Deus, Cláudia; Pereira, Cláudia V.; Simões, Rui F.; Rizvanov, Albert A.; et al. "Berberine-induced cardioprotection and Sirt3 modulation in doxorubicin-treated H9c2 cardiomyoblasts". Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1863 11 (2017): 2904-2923. http://dx.doi.org/10.1016/j.bbadis.2017.07.030.
    Published • 10.1016/j.bbadis.2017.07.030
  33. Silva, Ana Marta; Barbosa, Inês A.; Seabra, Cátia; Beltrão, Nuno; Santos, Raquel; Vega-Naredo, Ignacio; Oliveira, Paulo J.; # Cunha-Oliveira, Teresa. Corresponding author: # Cunha-Oliveira, Teresa. "Involvement of mitochondrial dysfunction in nefazodone-induced hepatotoxicity". Food and Chemical Toxicology 94 1 (2016): 148-158. http://dx.doi.org/10.1016/j.fct.2016.06.001.
    Published • 10.1016/j.fct.2016.06.001
  34. Branco, Ana F.; Ferreira, André; Simões, Rui F.; Magalhães-Novais, Sílvia; Zehowski, Cheryl; Cope, Elisabeth; Silva, Ana Marta; et al. Corresponding author: # Cunha-Oliveira, Teresa. "Ketogenic diets: from cancer to mitochondrial diseases and beyond". European Journal of Clinical Investigation 46 3 (2016): 285-298. http://dx.doi.org/10.1111/eci.12591.
    Open access • Published • 10.1111/eci.12591
  35. Naia, Luana; Ferreira, I. Luísa; Cunha-Oliveira, Teresa; Duarte, Ana I.; Ribeiro, Márcio; Rosenstock, Tatiana R.; Laço, Mário N.; et al. "Activation of IGF-1 and Insulin Signaling Pathways Ameliorate Mitochondrial Function and Energy Metabolism in Huntington’s Disease Human Lymphoblasts". Molecular Neurobiology 51 1 (2015): 331-348. http://dx.doi.org/10.1007/s12035-014-8735-4.
    Published • 10.1007/s12035-014-8735-4
  36. Ferreira, André; Serafim, Teresa L; Sardão, Vilma A; # Cunha-Oliveira, Teresa. Corresponding author: # Cunha-Oliveira, Teresa. "Role of mtDNA-related mitoepigenetic phenomena in cancer". European Journal of Clinical Investigation 45 S1 (2015): 44-49. http://dx.doi.org/10.1111/eci.12359.
    Open access • Published • 10.1111/eci.12359
  37. Moreira, Ana C; Branco, Ana F; Sampaio, Susana F; Cunha-Oliveira, Teresa; Martins, Tatiana R; Holy, Jon; Oliveira, Paulo J; et al. "Mitochondrial apoptosis-inducing factor is involved in doxorubicin-induced toxicity on H9c2 cardiomyoblasts". Biochimica et Biophysica Acta-Molecular Basis of Disease 1842 12 (2014): 2468-2478. http://hdl.handle.net/10316/41109.
    Open access • Published • 10.1016/j.bbadis.2014.09.015
  38. Branco, Ana F; Moreira, Ana C; Cunha-Oliveira, Teresa; Couto, Renata; Sardao, Vilma A; Rizvanov, Albert A; Palotas, Andras; et al. "ß-adrenergic over-stimulation and cardio-myocyte apoptosis: two receptors, one organelle, two fates?". Current Drug Targets 15 10 (2014): 956-964. http://dx.doi.org/10.2174/1389450115666140902124230.
    Published • 10.2174/1389450115666140902124230
  39. Perfeito, Rita; * Cunha-Oliveira, Teresa; Rego, Ana Cristina. "Reprint of: Revisiting oxidative stress and mitochondrial dysfunction in the pathogenesis of Parkinson disease—resemblance to the effect of amphetamine drugs of abuse". Free Radical Biology and Medicine 62 (2013): 186-201. http://dx.doi.org/10.1016/j.freeradbiomed.2013.05.042.
    Published • 10.1016/j.freeradbiomed.2013.05.042
  40. # Cunha-Oliveira, Teresa; Silva, Lisbeth; Silva, Ana Maria; Moreno, António J.; Oliveira, Catarina R.; Santos, Maria S.. Corresponding author: # Cunha-Oliveira, Teresa. "Mitochondrial complex I dysfunction induced by cocaine and cocaine plus morphine in brain and liver mitochondria". Toxicology Letters 219 3 (2013): 298-306. http://dx.doi.org/10.1016/j.toxlet.2013.03.025.
    Published • 10.1016/j.toxlet.2013.03.025
  41. # Cunha-Oliveira, Teresa; Rego, A. Cristina; Oliveira, Catarina R.. Corresponding author: # Cunha-Oliveira, Teresa. "Oxidative Stress and Drugs of Abuse: An Update". Mini-Reviews in Organic Chemistry 10 4 (2013): 321-334. http://dx.doi.org/10.2174/1570193X113106660026.
    Open access • Published • 10.2174/1570193X113106660026
  42. Bernardo, Telma C.; Cunha-Oliveira, Teresa; Serafim, Teresa L.; Holy, Jon; Krasutsky, Dmytro; Kolomitsyna, Oksana; Krasutsky, Pavel; Moreno, António M.; Oliveira, Paulo J.. "Dimethylaminopyridine derivatives of lupane triterpenoids cause mitochondrial disruption and induce the permeability transition". Bioorganic & Medicinal Chemistry 21 23 (2013): 7239-7249. http://dx.doi.org/10.1016/j.bmc.2013.09.066.
    Open access • Published • 10.1016/j.bmc.2013.09.066
  43. # Cunha-Oliveira, Teresa; Silva, Lisbeth; Silva, Ana Maria; Moreno, António J.; Oliveira, Catarina R.; Santos, Maria S.. Corresponding author: # Cunha-Oliveira, Teresa. "Acute effects of cocaine, morphine and their combination on bioenergetic function and susceptibility to oxidative stress of rat liver mitochondria". Life Sciences 92 24-26 (2013): 1157-1164. http://dx.doi.org/10.1016/j.lfs.2013.04.016.
    Open access • Published • 10.1016/j.lfs.2013.04.016
  44. Ribeiro, Márcio; Rosenstock, Tatiana R.; Cunha-Oliveira, Teresa; Ferreira, Ildete L.; Oliveira, Catarina R.; Rego, A. Cristina. "Glutathione redox cycle dysregulation in Huntington’s disease knock-in striatal cells". Free Radical Biology and Medicine 53 10 (2012): 1857-1867. http://dx.doi.org/10.1016/j.freeradbiomed.2012.09.004.
    Published • 10.1016/j.freeradbiomed.2012.09.004
  45. Pereira, Frederico C.; Cunha-Oliveira, Teresa; Viana, Sofia D.; Travassos, Ana S.; Nunes, Sara; Silva, Carlos; Prediger, Rui Daniel; et al. "Disruption of striatal glutamatergic/GABAergic homeostasis following acute methamphetamine in mice". Neurotoxicology and Teratology 34 5 (2012): 522-529. http://dx.doi.org/10.1016/j.ntt.2012.07.005.
    Published • 10.1016/j.ntt.2012.07.005
  46. Perfeito, R.; * Cunha-Oliveira, T.; Rego, A.C.. "Revisiting oxidative stress and mitochondrial dysfunction in the pathogenesis of Parkinson disease - Resemblance to the effect of amphetamine drugs of abuse". Free Radical Biology and Medicine 53 9 (2012): 1791-1806. http://www.scopus.com/inward/record.url?eid=2-s2.0-84867397192&partnerID=MN8TOARS.
    10.1016/j.freeradbiomed.2012.08.569
  47. Ferreira, I. Luisa; * Cunha-Oliveira, Teresa; Nascimento, Maria V.; Ribeiro, Márcio; Proença, M. Teresa; Januário, Cristina; Oliveira, Catarina R.; Rego, A. Cristina. "Bioenergetic dysfunction in Huntington's disease human cybrids". Experimental Neurology 231 1 (2011): 127-134. http://dx.doi.org/10.1016/j.expneurol.2011.05.024.
    Published • 10.1016/j.expneurol.2011.05.024
  48. Cunha-Oliveira, T.; Rego, A.C.; Garrido, J.; Borges, F.; Macedo, T.; Oliveira, C.R.. "Neurotoxicity of heroin-cocaine combinations in rat cortical neurons". Toxicology 276 1 (2010): 11-17. http://dx.doi.org/10.1016/j.tox.2010.06.009.
    Published • 10.1016/j.tox.2010.06.009
  49. Almeida, S.; Laço, M.; Cunha-Oliveira, T.; Oliveira, C.R.; Rego, A.C.. "BDNF regulates BIM expression levels in 3-nitropropionic acid-treated cortical neurons". Neurobiology of Disease 35 3 (2009): 448-456. http://dx.doi.org/10.1016/j.nbd.2009.06.006.
    Published • 10.1016/j.nbd.2009.06.006
  50. Almeida, Sandra; Cunha-Oliveira, Teresa; Laço, Mário; Oliveira, Catarina R.; Rego, A. Cristina. "Dysregulation of CREB Activation and Histone Acetylation in 3-Nitropropionic Acid-Treated Cortical Neurons: Prevention by BDNF and NGF". Neurotoxicity Research 17 4 (2009): 399-405. http://dx.doi.org/10.1007/s12640-009-9116-z.
    Open access • Published • 10.1007/s12640-009-9116-z
  51. Cunha-Oliveira, T.; Rego, A.C.; Oliveira, C.R.; Cunha-Oliveira, Teresa; Rego, Ana Cristina; Oliveira, Catarina R.. "Cellular and molecular mechanisms involved in the neurotoxicity of opioid and psychostimulant drugs". Brain Research Reviews 58 1 (2008): 192-208. http://dx.doi.org/10.1016/j.brainresrev.2008.03.002.
    10.1016/j.brainresrev.2008.03.002
  52. Cunha-Oliveira, T.; Rego, A.C.; Garrido, J.; Borges, F.; Macedo, T.; Oliveira, C.R.. "Street heroin induces mitochondrial dysfunction and apoptosis in rat cortical neurons". Journal of Neurochemistry 101 2 (2007): 543-554. http://dx.doi.org/10.1111/j.1471-4159.2006.04406.x.
    10.1111/j.1471-4159.2006.04406.x
  53. Cunha-Oliveira, T; Rego, AC; Macedo, T; Oliveira, CR. "Adaptation to oxidative stress in the chronic effects of cocaine and amphetamine". Free Radical Research 41 (2007): S22-S22. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000252296300068&KeyUID=WOS:000252296300068.
  54. Cunha-Oliveira, T.; Rego, A.C.; Cardoso, S.M.; Borges, F.; Swerdlow, R.H.; Macedo, T.; de Oliveira, C.R.. "Mitochondrial dysfunction and caspase activation in rat cortical neurons treated with cocaine or amphetamine". Brain Research 1089 1 (2006): 44-54. http://dx.doi.org/10.1016/j.brainres.2006.03.061.
    Published • 10.1016/j.brainres.2006.03.061
  55. Domingues, A.; * Oliveira, T.C.; Laço, M.L.N.; Macedo, T.R.A.; Oliveira, C.R.; Rego, A.C.. "Expression of NR1/NR2B N-methyl-D-aspartate receptors enhances heroin toxicity in HEK293 cells". Annals of the New York Academy of Sciences 1074 (2006): 458-465. http://dx.doi.org/10.1196/annals.1369.046.
    Published • 10.1196/annals.1369.046
  56. Cunha-Oliveira, Teresa; Rego, A Cristina; Morgadinho, M Teresa; Macedo, Tice R; Oliveira, Catarina R. "Efeito crónico da heroína e do peróxido de hidrogénio em células PC12". Coimbra Médica V 2 1 (2006): 21-29. http://hdl.handle.net/10316/18520.
    Open access • Published
  57. Cunha-Oliveira, Teresa; Rego, A. Cristina; Morgadinho, Maria Teresa; Macedo, Tice; Oliveira, Catarina Resende. "Differential cytotoxic responses of PC12 cells chronically exposed to psychostimulants or to hydrogen peroxide". Toxicology 217 1 (2006): 54-62. http://dx.doi.org/10.1016/j.tox.2005.08.022.
    Open access • 10.1016/j.tox.2005.08.022
  58. Milhazes, N.; Cunha-Oliveira, T.; Martins, P.; Garrido, J.; Oliveira, C.; Rego, A.C.; Borges, F.. "Synthesis and cytotoxic profile of 3,4-methylenedioxymethamphetamine ("ecstasy") and its metabolites on undifferentiated PC12 cells: A putative structure-toxicity relationship". Chemical Research in Toxicology 19 10 (2006): 1294-1304. http://www.scopus.com/inward/record.url?eid=2-s2.0-33750209029&partnerID=MN8TOARS.
    10.1021/tx060123i
  59. Cunha-Oliveira, T.; Rego, A.C.; Macedo, T.; Oliveira, C.R.. "Drugs of abuse induce apoptotic features in PC12 cells". Annals of the New York Academy of Sciences 1010 1 (2003): 667-670. http://dx.doi.org/10.1196/annals.1299.121.
    Published • 10.1196/annals.1299.121
  60. # Cunha-Oliveira, T.; Rego, A.C.; Morgadinho, M.T.; Macedo, T.R.A.; Oliveira, C.R.. Corresponding author: # Cunha-Oliveira, T.. "Toxic effects of opioid and stimulant drugs on undifferentiated PC12 cells". Annals of the New York Academy of Sciences 965 (2002): 487-496. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036290212&partnerID=MN8TOARS.
    Published • 10.1111/j.1749-6632.2002.tb04190.x
Manual
  1. Cunha-Oliveira, T.; Rego, A.C.. Mitochondrial Apoptotic Pathway- https://youtu.be/9tXwp9hli7w. 2007.
  2. Rego, A.C.; Cunha-Oliveira, T.; Almeida, L.P.. Molecular mechanisms of Huntington's disease neuropathology - https://youtu.be/V5lQWNnP71Y. 2007.
Newspaper article
  1. Cunha-Oliveira, T.. "Qual o efeito das drogas de abuso no cérebro?", i, 2015, http://www.cienciaviva.pt/saberastu/.
Online resource
  1. Cunha-Oliveira, T.; Sónia Pinho; Paulo J. Oliveira. Project description. 2024. https://figshare.com/articles/online_resource/Project_description/26015728.
    10.6084/m9.figshare.26015728
Thesis / Dissertation
  1. OLIVEIRA, MARIA. "Neuronal dysfunction induced by drugs of abuse". PhD, Universidade de Coimbra Faculdade de Ciencias e Tecnologia, 2007. http://hdl.handle.net/10316/10124.
  2. Cunha-Oliveira, T.. "Neurotoxicidade induzida por drogas de abuso". Master, Universidade de Coimbra Faculdade de Ciencias e Tecnologia, 2003.
  3. Cunha-Oliveira, T.. "Estudo de genética populacional em STR's". Degree, Universidade de Coimbra Faculdade de Ciencias e Tecnologia, 1999.

Other

Dataset
  1. Changes in gene expression in cells cultured in HGm or adapted to LGm or OXPHOSm - PCA.
    10.6084/M9.FIGSHARE.19102928
  2. Mitochondrial energy levels and network organization in NHDF cells cultured in HGm or adapted to OXPHOSm or to LGm..
    10.6084/M9.FIGSHARE.19102916
  3. Changes in gene expression in cells cultured in HGm or adapted to LGm or OXPHOSm.
    10.6084/M9.FIGSHARE.19102925
  4. Mitochondrial metabolism and substrate preference..
    10.6084/M9.FIGSHARE.19102922
  5. Changes in gene expression in cells cultured in HGm or adapted to LGm or OXPHOSm - Correlations..
    10.6084/M9.FIGSHARE.19103084
  6. Cunha-Oliveira, T.; Filomena Silva. Glutathione redox cycle in lymphoblasts from ALS patients and matched controls.
    10.6084/m9.figshare.19146437
  7. Cunha-Oliveira, T.; Filomena Silva. Cell lines, antibodies and primers used for oxidative stress profiling of ALS and control lymphoblasts.
    10.6084/m9.figshare.19146548
  8. Cunha-Oliveira, T.; Filomena Silva. Growth curves of ALS and control lymphoblasts.
    10.6084/m9.figshare.19146161
  9. Cunha-Oliveira, T.; Filomena Silva. SOD expression and activity in ALS lymphoblasts and matched controls.
    10.6084/m9.figshare.19146332
  10. Cunha-Oliveira, T.; Filomena Silva. Antioxidant defenses in lymphoblasts from ALS patients and matched controls..
    10.6084/m9.figshare.19146482
  11. Cunha-Oliveira, T.; Filomena Silva. Integrative analysis of oxidative stress profiles defenses of lymphoblasts from ALS patients and matched controls.
    10.6084/m9.figshare.19146491
  12. Cunha-Oliveira, T.; Filomena Silva. Oxidative stress markers and response to oxidative stimulus in lymphoblasts from ALS patients.
    10.6084/m9.figshare.19146386
  13. Cunha-Oliveira, T.; Filomena Silva. Impact of experimental group, disease, mutation, age and sex on lymphoblast metabolic profiles..
    10.6084/m9.figshare.19229268
  14. Cunha-Oliveira, T.; Filomena Silva. Pathways associated with ATP production in lymphoblasts from ALS patients with mutant SOD1 (mutSOD1) or unknown mutation (undSOD1) and respective controls..
    10.6084/m9.figshare.19229205
  15. Cunha-Oliveira, T.; Filomena Silva. Oxygen consumption rate (OCR) and extracellular acidification rate (ECAR) in lymphoblasts from ALS patients with mutant SOD1 (mutSOD1) and unknown mutation (undSOD1)..
    10.6084/m9.figshare.19229190
  16. Cunha-Oliveira, T.; Filomena Silva. Mitochondrial oxidation of TCA cycle intermediates, fatty acids, amino acids and other substrates in lymphoblasts from ALS patients with mutant SOD1 (mutSOD1) or unknown mutation (undSOD1) and respective controls..
    10.6084/m9.figshare.19229229
  17. Cunha-Oliveira, T.; Filomena Silva. Mitochondrial respiratory chain subunits, biogenesis markers and mitochondrial membrane potential in lymphoblasts from ALS patients with mutant SOD1 (mutSOD1) or unknown mutation (undSOD1) and respective controls..
    10.6084/m9.figshare.19229214
  18. Cunha-Oliveira, T.; Filomena Silva. Metadata and Summarized results.
    10.6084/m9.figshare.19229310
Other output
  1. Oxidative stress profiles of lymphoblasts from Amyotrophic Lateral Sclerosis patients with or without known SOD1 Mutations. 2022. # Cunha-Oliveira, T.; Franco Silva, D.; Segura, L.; Baldeiras, I.; Marques, R.; Rosenstock, T.; Oliveira, P. J.; Silva, F.S.G.. https://www.biorxiv.org/content/10.1101/2022.03.03.482309v1.
    10.1101/2022.03.03.482309
  2. Evaluation of 6-Hydroxydopamine and Rotenone In Vitro Neurotoxicity on Differentiated SH-SY5Y Cells Using Applied Computational Statistics. Data on mitochondrial parameters was acquired and analyzed using unsupervised (hierarchical clustering) and supervised (decision tree) machine learning methods. Both biochemical and computational analyses resulted in an evident distinction between the neurotoxic effects of 6-hydroxydopamine and rotenone, specifically for the highest concentrations of both compounds.. 2022. Simões, Rui; Oliveira, P.J.; # Cunha-Oliveira, T.; Pereira, F.B.. https://dx.doi.org/10.20944/preprints202203.0093.v1.
  3. Mitochondrial and metabolic remodeling in human skin fibroblasts in response to glucose availability. 2021. Costa, C. F.; Pinho, S.A.; Pinho, S. L.; Miranda-Santos, I.; Bagshaw, O.; Stuart, J.; Oliveira, P.J.; # Cunha-Oliveira, T.. Corresponding author: # Cunha-Oliveira, T.. https://www.biorxiv.org/content/10.1101/2021.02.24.432508v1.
    10.1101/2021.02.24.432508
  4. Quantitative Analysis of Neuronal Mitochondrial Movement Reveals Patterns Resulting from Neurotoxicity of Rotenone and 6-Hydroxydopamine. 2021. Simoes, R. F.; Pino, R.; Moreira-Soares, M.; Kovarova, J.; Neuzil, J.; Travasso, R.; Oliveira, P.J.; # Cunha-Oliveira, T.; Pereira, F. B.. Corresponding author: # Cunha-Oliveira, T.. https://www.biorxiv.org/content/10.1101/2021.02.24.432715v1.
    10.1101/2021.02.24.432715
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2022/06/17 The importance of metabolic contexts in intracellular redox homeostasis on human dermal fibroblasts. The Future of Redox Biology, Siena, 17 a 19 June 2022
(Sienna, Italy)
2021/10/27 MITOCHONDRIAL METABOLIC PROFILES OF LYMPHOBLASTS OBTAINED FROM ALS PATIENTS WITH OR WITHOUT KNOWN SOD1 MUTATIONS 12th Congress on Targeting Mitochondria 2021
World Mitochondria Society
2021/10/13 REVERTING MITOCHONDRIAL IMPAIRMENT IN SKIN FIBROBLASTS FROM PARKINSON'S DISEASE PATIENTS BY USING A MITOCHONDRIA-TARGETED ANTIOXIDANT ANTIOXCIN4 Paris Redox 2021: 23rd International Conference on Oxidative Stress, Redox Homeostasis & Antioxidants
International Society of Antioxidants
2021/09/01 Scientific integrity and data organization “Summer with Science: Interdisciplinary Research, Development and Innovation in Pathophysiology of Diseases Dependent on Lifestyles and Aging
CNC, Center for Neuroscience and Cell Biology
2021/06/11 Oxidative Stress Profile in Lymphoblasts from Amyotrophic Lateral Sclerosis Patients with SOD1 Mutations and Unknown mutations 55th Annual Meeting of the European Society for Clinical Investigation
European Society for Clinical Investigation (ESCI)
2021/06/11 Manipulation of glucose availability promotes different in vitro redox environments in human dermal fibroblasts 55th Annual Meeting of the European Society for Clinical Investigation
European Society for Clinical Investigation (ESCI)
2021/06/11 A novel phenolic acid-based mitochondria-targeted antioxidant improves cellular responses to oxidative stress in fibroblasts from sporadic Parkinson's disease patients 55th Annual Meeting of the European Society for Clinical Investigation
European Society for Clinical Investigation (ESCI)
2021/06/11 AntiOxCIN4 a new mitochondriotropic derivative based on the natural polyphenol caffeic acid reverts cellular and mitochondrial metabolic defects of fibroblasts from idiopathic Parkinson's Disease 55th Annual Meeting of the European Society for Clinical Investigation
European Society for Clinical Investigation (ESCI)
2021/06/10 Visualization of metabolic rewiring of NHDF cells in response to extracellular glucose concentration 55th Annual Meeting of the European Society for Clinical Investigation
European Society for Clinical Investigation (ESCI)
2021/06/10 Evaluation of 6-Hydroxydopamine and Rotenone in Vitro Neurotoxicity in SH-SY5Y Cells using Computational Applied Statistics 55th Annual Meeting of the European Society for Clinical Investigation
European Society for Clinical Investigation (ESCI)
2021/06/10 Multi-dimensional Analysis of Metabolic and Mitochondrial Dysfunction Parameters in Lymphoblasts from Amyotrophic Lateral Sclerosis Patients 55th Annual Meeting of the European Society for Clinical Investigation
European Society for Clinical Investigation (ESCI)
2021/06/09 Good practices with experimental data Pre-meeting course on Bioinformatic Tools for Data Analysis
55th Annual Meeting of the European Society for Clinical Investigation
2021/01/20 (Biological) data practices and science integrity Fundamentals of Cellular and Molecular Metabolism: Relevance for Health and Disease
ITMO University (St. Petersburg, Russia)
2020/11/17 PERSONALIZED MITOCHONDRIAL MEDICINE: COMPARING METABOLIC TOOLS TO IMPROVE HUMAN SKIN FIBROBLASTS AS MODELS Mitochondria Aging and Disease Retreat
CNC, Center for Neuroscience and Cell Biology
2020/10/29 METABOLIC RECONFIGURATION IN HUMAN SKIN FIBROBLASTS AS A TOOL FOR PERSONALIZED MITOCHONDRIAL MEDICINE 11th World Congress on Targeting Mitochondria
World Mitochondria Society
2020/10/14 Tools for Data Analysis and Machine Learning in Cell Metabolism Studies Summer Course in Interdisciplinary Research, Development and Innovation in Cellular and Molecular Metabolism
Instituto de Investigação Interdisciplinar, Universidade de Coimbra (Coimbra, Portugal)
2020/10/01 Data Analysis using Pivot Tables and Orange Summer Course in Interdisciplinary Research, Development and Innovation in Cellular and Molecular Metabolism
Instituto de Investigação Interdisciplinar, Universidade de Coimbra (Cantanhede, Portugal)
2020/09/24 Mitochondria as biosensors for disease staging and therapeutic response ESCI Virtual Meeting 2020 – COVID19 edition
European Society for Clinical Investigation (ESCI)
2020/09/24 Morphological and functional mitochondrial remodeling in human skin fibroblasts cultured with different metabolic fuels. ESCI Virtual Meeting 2020 – COVID19 edition
European Society for Clinical Investigation ESCI)
2020/09/24 Differentiated SH-SY5Y cells as a cellular model to study mitochondrial physiology and dynamics ESCI Virtual Meeting 2020 – COVID19 edition
European Society for Clinical Investigation (ESCI)
2020/09/24 Impact of Rebaudioside A in the metabolism of breast cancer cells and assessment of its chemotherapeutic potential ESCI Virtual Meeting 2020 – COVID19 edition
European Society for Clinical Investigation (ESCI)
2020/09/24 Non-supervised analysis of neurotoxicity of mitochondrial poisons 6-OHDA and rotenone ESCI Virtual Meeting 2020 – COVID19 edition
European Society for Clinical Investigation (ESCI)
2020/09/24 A Data Science Approach to Sub-chronic Doxorubicin Cardiotoxicity Reveals Hidden Patterns of Metabolic Remodeling ESCI Virtual Meeting 2020 – COVID19 edition
European Society for Clinical Investigation (ESCI)
2020/09/24 Data Extraction from Mitochondrial Motility Tracking using Computational Algorithms ESCI Virtual Meeting 2020 – COVID19 edition
European Society for Clinical Investigation (ESCI)
2020/09/24 Exploratory analysis of mitochondrial metabolism in lymphoblasts from Amyotrophic Lateral Sclerosis patients to reveals discriminant biomarkers ESCI Virtual Meeting 2020 – COVID19 edition
European Society for Clinical Investigation (ESCI)
2020/09/24 Glycolytic fluxes and metabolic profiles distinguish amyotrophic lateral sclerosis patients from healthy controls ESCI Virtual Meeting 2020 – COVID19 edition
European Society for Clinical Investigation (ESCI)
2020/05/12 Data Analysis using MS Excel. Pivot Tables and Pivot Charts. MitoXT lab meetings
CNC, Center for Neuroscience and Cell Biology (Portugal)
2020/03/12 Maternal Obesity During Pregnancy Induces Oxidative Stress and Mitochondria Functional Alterations in the Maternal Liver “Translating Reproductive Science to the Bedside” 67th Annual Meeting of the Society for Reproductive Investigation (SRI), March 10 – 14, 2020
Society for Reproductive Investigation (Vancouver, BC, Canada, Canada)
2020/03/09 Bioinformatics and machine learning in cell biology and metabolism The Avenging Metabolism in Human Disease: Endgame!
BEB PhD Program @ CNC (Coimbra, Portugal)
2019/09/04 Unraveling metabolic effects underlying acute cardiotoxicity of the antineoplastic drug Doxorubicin FEBS 2019 Advanced Course. Oncometabolism: From Conceptual Knowledge to Clinical Applications
FEBS (Luso, Portugal)
2019/07/08 Metabolic remodeling and susceptibility to stress after forcing OXPHOS in human skin fibroblasts Mitochondrial Physiology / MitoEAGLE Training School 2019: Mitochondrial respiratory physiology: challenges on data sharing, reproducibility, and interpretation.
Mitochondrial Physiology Society (Coimbra, Portugal)
2019/07/01 Machine Learning and Uses in Mitochondrial Research Treatment School 3 on “Novel technological developments for metabolic studies”
H2020-MSCA-ITN TREATMENT GA721236 (Coimbra, Portugal)
2019/03/15 Maternal Obesity (MO) in an Ovine Model Results in Disruption of Offspring (F1) Mitochondrial Respirasomes (https://www.abstractsonline.com/pp8/#!/6816/presentation/3950) 66th Annual Scientific Meeting of the Society for Reproductive Investigation (SRI)
Society for Reproductive Investigation (SRI) (Paris, France)
2019/03/06 MitoScreening: Aplicação de Aprendizagem Automática em problemas da Biologia III MeetLab
Department of Life Sciences , FCTUC (Coimbra, Portugal)
2018/10/25 Mitochondrial DNA. Background for interpretation of mtDNA copy number and transcription data and experimental design. MitoXT lab meetings
CNC, Center for Neuroscience and Cell Biology (Cantanhede, Portugal)
2018/10/22 Mitochondrial remodeling after forcing OXPHOS in human skin fibroblasts International workshop on: Mitochondrial DNA and Derived Peptides in Health and Disease
Center for Neuroscience and Cell Biology
2018/03/11 Diabetes e doença cardíaca: uma herança da vida intrauterina? 14º Congresso Português de Diabetes
Sociedade Portuguesa de Diabetologia (Vilamoura, Portugal)
2017/11/16 Master Class on "qPCR principles and applications" MitoXT lab meetings
CNC, Center for Neuroscience and Cell Biology (Cantanhede, Portugal)
2017/07/27 Doxorubicin toxicity and mitochondrial dysfunction in mouse induced pluripotent stem cells-derived cardiomyocytes Mitochondrial Physiology Society Training School
Mitochondrial Physiology Society (Obergurgl, Austria)
2017/05/19 Mitochondrial dysfunction and p53 signaling in mouse stem cell-derived cardiomyocytes exposed to doxorubicin 51st Annual Meeting of the European Society for Clinical Investigation
European Society for Clinical Investigation (Genoa, Italy)
2017/05/19 Altered Metabolism and Oxidative Stress in Skin Fibroblasts from Parkinson’s Disease Patients 51st Annual Meeting of the European Society for Clinical Investigation
European Society for Clinical Investigation (Genoa, Italy)
2017/05/19 Single nanomolar treatment with doxorubicin triggers mitochondrial adaptative responses in rat H9c2 cardiomyoblasts 51st Annual Meeting of the European Society for Clinical Investigation
European Society for Clinical Investigation (Genoa, Italy)
2017/05/19 Exposure of Human Bronchial Epithelial Cells to the Lung Carcinogen Hexavalent Chromium Confers Resistance to Thermal Shock and Interferes with the Stress Response 51st Annual Meeting of the European Society for Clinical Investigation
European Society for Clinical Investigation (Genoa, Italy)
2017/05/19 Remodeling of Cardiac Mitochondrial Profile in the Fetal Baboon by Moderate Global Maternal Nutrient Reduction 51st Annual Meeting of the European Society for Clinical Investigation
European Society for Clinical Investigation (Genoa, Italy)
2017/05/19 Maternal Obesity (MO) in Sheep Decreases Fetal Hepatic Mitochondrial Respiratory Chain Activity and Total Mitochondrial Lipids 51st Annual Meeting of the European Society for Clinical Investigation
European Society for Clinical Investigation (Genoa, Italy)
2016/06/23 Hexavalent Chromium, an Occupational Lung Carcinogen, Attenuates Thermal Shock Effects and Interferes with the Stress Response in Human Bronchial Epithelial Cells ICOETOX 2016
International Conference on Occupational & Environmental Toxicology (Porto, Portugal)
2016/04/29 Causes and consequences of mitochondrial dysfunction induced by drugs of abuse 50th Annual Meeting of the European Society for Clinical Investigation
European Society for Clinical Investigation (Paris, France)
2016/04/29 Maternal nutrition and fetal mitochondrial fitness 50th Meeting of the European Society for Clinical Investigation
European Society for Clinical Investigation (Paris, France)
2016/03/19 Maternal Obesity (MO) in Sheep Decreases Fetal Hepatic Mitochondrial Respiratory Chain Activity 63rd Annual Scientific Meeting of the Society for Reproductive Investigation (SRI)
Society for Reproductive Investigation (SRI) (Montreal, Canada)
2016/01/28 Exposure of human epithelial bronchial cells to hexavalent chromium, a lung carcinogen, downregulates HSP90a and confers resistance to stress 5th CIMAGO congress
Centro de Investigação em Meio Ambiente, Genética e Oncobiologia (Coimbra, Portugal)
2015/05/30 Doxorubicin treatment induces persistent alterations in cardiomyoblast mitochondrial gene expression 49th Annual Meeting of the European Society for Clinical Investigation
European Society for Clinical Investigation (Cluj-Napoca, Romania)
2015/02/28 Avaliação da morte celular em células cardíacas. Preparação e tratamento de células com venenos mitocondriais. (Evaluation of cell death in cardiac cells. Preparation and treatment of cells with mitochondrial poisons) Advanced course on Biomedicine: Mitochondria and Disease (2015)
Instituto de Educação e Cidadania (IEC) (Mamarrosa, Portugal)
2015/02/03 Mitochondrial characterization of human breast cancer cell lines for in vitro cancer research Cancer Epigenetics and Metabolism: Connecting the Dots
Center for Neuroscience and Cell Biology (Cantanhede, Portugal)
2015/02/03 Persistent effects in mitochondrial genes transcription after incubation of H9c2 cells with the anticancer drug Doxorubicin: an epigenetic origin? Cancer Epigenetics and Metabolism: Connecting the Dots
Center for Neuroscience and Cell Biology (Cantanhede, Portugal)
2015/01/17 Produção de energia na célula. Glicólise, Ciclo de Krebs e fosforilação oxidativa. (Cellular energy production. Glycolysis, Krebs Cycle and Oxidative Phosphorylation) Advanced course on Biomedicine: Mitochondria and Disease (2015)
Instituto de Educação e Cidadania (IEC) (Mamarrosa, Portugal)
2014/12/20 Doxorubicin Causes Down-Regulation of Transcripts for Metabolic and Epigenetic Remodeling Enzymes XVIII Congress of the Portuguese Biochemical Society
Sociedade Portuguesa de Bioquímica (Coimbra, Portugal)
2014/07/17 Deficits of pyruvate dehydrogenase and mitochondrial dysfunction in Huntington's disease - role of histone deacetylase inhibitors 18th European BioEnergetics Conference (EBEC)
(Lisbon, Portugal)
2014/06/28 Sodium butyrate protects against pyruvate dehydrogenase dysfunction in in vitro and in vivo Huntington’s disease models 28ª Reunião do Grupo de Estudo de Envelhecimento Cerebral e Demências
Grupo de Estudo de Envelhecimento Cerebral e Demências (Aveiro, Portugal)
2014/05/31 Avaliação da morte celular em células cardíacas. Preparação e tratamento de células com venenos mitocondriais. (Evaluation of cell death in cardiac cells. Preparation and treatment of cells with mitochondrial poisons) Advanced course on Biomedicine: Mitochondria and Disease (2014)
Instituto de Educação e Cidadania (IEC) (Mamarrosa, Portugal)
2014/05/03 Involvement of Mitochondrial Apoptosis-inducing Factor in Doxorubicin-induced Cardiotoxicity 48th Annual Scientific Meeting of the European Society for Clinical Investigation (ESCI)
European Society for Clinical Investigation (Utrecht, Netherlands)
2013/11/16 Avaliação da morte celular em células cardíacas. Preparação e tratamento de células com venenos mitocondriais. (Evaluation of cell death in cardiac cells. Preparation and treatment of cells with mitochondrial poisons) Advanced course on Biomedicine: Mitochondria and Disease (2013)
Instituto de Educação e Cidadania (IEC) (Mamarrosa, Portugal)
2013/10/12 Produção de energia na célula. Glicólise, Ciclo de Krebs e Fosforilação Oxidativa. (Cellular energy production. Glycolysis, Krebs' Cycle and Oxidative Phosphorylation) Advanced course on Biomedicine: Mitochondria and Disease (2013)
Instituto de Educação e Cidadania (IEC) (Mamarrosa, Portugal)
2013 Role of histone deacetylase inhibitors on pyruvate dehydrogenase dysfunction in Huntington’s disease striatal cells 47th Annual Scientific Meeting of the European Society for Clinical Investigation (ESCI)
European Society for Clinical Investigation (ESCI) (Albufeira, Portugal, Portugal)
2012 Impacto da cocaína no cérebro II Congresso Nacional de Patologia Dual e Comportamentos Aditivos - DEPENDÊNCIA GRAVE E PATOLOGIA DUAL: MENTE DOENTE?
(Coimbra, Portugal, Portugal)
2012 Bioenergetic function and susceptibility to oxidative stress in rat liver mitochondria exposed to cocaine, morphine and their combination V Jornadas de Bioquímica
UTAD (Vila Real, Portugal)
2011 Molecular and cellular mechanisms of neurotoxicity of drugs of abuse CBTox 2011- Congresso Brasileiro de Toxicologia
Sociedade Brasileira de Toxicologia (São Paulo, Brazil)
2011 Molecular interaction between cocaine and opioids. Implications on speedball's toxicity Eurotox 2011 (47th Congress of the European Societies of Toxicology)
( Paris, France, France)
2011 Importance of Chemical and Pharmacodynamic Interactions in Speedball Abuse: The Medicinal Chemistry Outlook First III-UC Researcher Forum
Institute for Interdisciplinary Research University of Coimbra (Coimbra, Portugal)
2011 Changes in energy metabolism and cell death induced by heroin, morphine or their combinations with cocaine First III-UC Researcher Forum
Institute for Interdisciplinary Research University of Coimbra (Coimbra, Portugal)
2011 Interactions between cocaine and opioids. Implications in speedball toxicity CBTox 2011- Congresso Brasileiro de Toxicologia, Centro de Convenções de Ribeirão Preto
Sociedade Brasileira de Toxicologia (São Paulo, Brazil)
2011 Bioenergetic dysfunction in Huntington's disease human cybrids XXV Meeting of the “Grupo de Estudos do Envelhecimento Cerebral e Demência"
Grupo de Estudos do Envelhecimento Cerebral e Demência (Tomar, Portugal)
2011 Effects Of Cocaine, Morphine And Their Combination In Liver Mitochondrial Bioenergetics XLI Reunião Anual da Sociedade Portuguesa de Farmacologia, XXIX Reunião de Farmacologia Clínica e X Reunião de Toxicologia
(Coimbra, Portugal)
2011 Striatal Methamphetamine-Induced Neurotoxicity Does Not Translate Into Motor Uncoordination In Mice XLI Reunião Anual da Sociedade Portuguesa de Farmacologia, XXIX Reunião de Farmacologia Clínica e X Reunião de Toxicologia
(Coimbra, Portugal)
2011 Time-Dependent Effects of Methamphetamine on Striatal Neurochemical and Astrocytic Profile and Motor Coordination in Mice 3rd IDARS/ISN/ESN Satellite Meeting
IDARS/ISN/ESN (Istambul, Turkey)
2011 IGF-1 recovers mitochondrial function in Huntington’s disease human lymphoblasts SINAL 2011 5th Annual Meeting on Cell Signaling
(Coimbra, Portugal)
2011 Bioenergetic dysfunction in Huntington's Disease human cybrids XII Meeting of the Portuguese Neuroscience Society
Portuguese Neuroscience Society (Lisbon, Portugal)
2011 Apoptotic cell death, oxidative stress and impairment of energy metabolism in Huntington's disease human cybrids First III-UC Researcher Forum
Institute for Interdisciplinary Research (Coimbra, Portugal)
2010 Neurotoxicity of heroin, cocaine and their combinations O cérebro e a vontade: actualizações em dependências
Instituto da Droga e da Toxicodependência (Coimbra, Portugal)
2010 Heroína e cocaína. Mistura explosiva da rua para o laboratório XV Simposium do Núcleo de Estudantes de Farmácia da Universidade de Coimbra
Núcleo de Estudantes de Farmácia da Universidade de Coimbra (Coimbra, Portugal)
2010 Impacto da cocaína e do speedball no sistema nervoso central O Modelo Psicossocial: Do conceito à prática
Instituto da Droga e da Toxicodependência- Delegação Regional de Lisboa e Vale do Tejo- CRI Lisboa Ocidental- ET Restelo (Lisboa, Portugal)
2009 Toxicity of drugs of abuse Debate sobre "Drogas de abuso: drogas leves, não tão leves..."
Ciclo de conferências e debates- Introdução às ciências forenses e às neurociências (Coimbra, Portugal)
2009 Estudos laboratoriais da toxicidade e mecanismos de acção das drogas Conferência: "As drogas: da rua para o laboratório"
Instituto de Educação e Cidadania (Mamarrosa, Oliveira do Bairro, Portugal)
2008 Does heroin induce neuronal dysfunction? International Symposium on Drugs of Abuse
International Drug Abuse Research Society (Ponta Delgada, Portugal)
2008 Cellular and molecular mechanisms of cocaine and amphetamine neurotoxicity
(Portugal)
2007 Mecanismos de regulação do peso corporal e do metabolismo energético: possíveis alvos terapêuticos na toxicodependência? Olhares Cruzados sobre a Droga em Portugal
Instituto da Droga e da Toxicodependência (Sesimbra, Portugal)
2006 Neurotoxicidade da cocaína e da anfetamina Encontro da Unidade de Desabituação de Coimbra do IDT
Instituto da Droga e da Toxicodependência (Coimbra, Portugal)
2005 Apoptotic cascades involved in heroin-induced neurodegeneration 19º Encontro do Grupo de Estudos do Envelhecimento Cerebral e Demência
Grupo de Estudos do Envelhecimento Cerebral e Demência (Tomar, Portugal)
2004 Contribuição de diferentes subunidades dos receptores NMDA na citotoxicidade da heroína IV Congresso de Investigação em Medicina
Faculdade de Medicina da Universidade de Coimbra (Coimbra, Portugal)
2003 Cell injury induced by drugs of abuse Encontro do Centro de Atendimento a Toxicodependentes
Instituto da Droga e da Toxicodependência (Coimbra, Portugal)
2003 Mitochondrial dysfunction and caspases activation in the neurotoxicity induced by heroin, amphetamine or cocaine in cortical cultures International summer school on "Molecular mechanisms in homeostasis and disease"
FEBS (Federation of European Biochemical Societies) (Spetses, Greece)
2002 Mechanisms of cell damage induced by drugs of abuse Mesas Redondas em Biomedicina
Faculdade de Medicina da Universidade de Coimbra (Coimbra, Portugal)
2002 Involvement of apoptosis in the cytotoxicity induced by drugs of abuse: cocaine, heroin and amphetamine XXXIII Congresso da Sociedade Portuguesa de Farmacologia e XXI Congresso de Farmacologia Clínica
Sociedade Portuguesa de Farmacologia (Lisboa, Portugal)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2018/09/01 - Current MitoInformatics - Computational Tools for the Assessment of Mitochondrial Health
Supervisor of Sónia Andreia de Almeida Pinho
 PhD Programme in Experimental Biology and Biomedicine (PDBEB) (PhD)
Centro de Neurociências e Biologia Celular da Universidade de Coimbra, Portugal
2020/09/01 - 2021/12/15 Molecular mechanisms of hexavalent chromium carcinogenicity: an in vitro study
Co-supervisor of Adriana Sofia Soares Mata
 Bioquímica (Master)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2019/11/08 - 2021/10/30 MitoScreening: Development and Validation of Innovative Screening Methods for Mitochondrial Health Modulators
Supervisor of Inês Vasconcelos Miranda Santos
 PostDoc (Other)
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2021/02/15 - 2021/10/26 Impact of metabolic remodeling in the redox response of human fibroblasts
Supervisor of Kátia Patrícia Monteiro Ribeiro
 Bioquímica (Degree)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2019/05/13 - 2021/07/22 Avaliação do potencial citotóxico e citoprotetor do óleo essencial de Tomilho-bela-luz
Supervisor of Rafael Alexandre Ferreira
 Biotecnologia (Degree)
Instituto Politécnico de Coimbra Escola Superior Agrária de Coimbra, Portugal
2016 - 2021/07/20 Neuronal mitochondrial metabolism and dynamic profiling under physiological and pathological conditions using biological-based machine learning approaches.
Co-supervisor of Rui Fernando Vieira Lisboa Matias Simões
 Biologia Experimental e Biomedicina (PhD)
Universidade de Coimbra, Portugal

Centro de Neurociências e Biologia Celular da Universidade de Coimbra, Portugal
2019/09/01 - 2020/12/09 Impact of Rebaudioside A in cancer cell metabolism: Potential as a safe chemotherapeutic adjuvant
Supervisor of Gonçalo José Martins Afonso
 Bioquímica (Master)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2019/09/01 - 2020/12/03 Impact of Hexavalent Chromium on the Stress Response in the BEAS-2B Cell Line
Co-supervisor of Margarida Conceição Moreira Sobral
 Bioquímica (Master)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2020/08/01 - 2020/10/30 Metabolic remodeling induced by Stevia derivatives in breast cancer cell models
Supervisor of Gonçalo José Martins Afonso
 Summer School on Methodologies of Scientific Research- Interdisciplinary Research, Development and Innovation in Cellular and Molecular Metabolism (Specialization course)
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2020/08/01 - 2020/10/30 Evaluation of mitochondrial and metabolic dysfunction in lymphoblasts from patients with Amyotrophic Lateral Sclerosis
Co-supervisor of Beatriz Rodrigues Moreira da Silva
 Summer School on Methodologies of Scientific Research- Interdisciplinary Research, Development and Innovation in Cellular and Molecular Metabolism (Specialization course)
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2019/05/13 - 2020/07/24 Avaliação do potencial citotóxico e citoprotetor do óleo essencial de perpétua-das-areias
Supervisor of Susana Raquel Tiago Nogueira
 Biotecnologia (Degree)
Instituto Politécnico de Coimbra Escola Superior Agrária de Coimbra, Portugal
2020/02/01 - 2020/07/23 Análise Inteligente de Dados Bioenergéticos Mitocondriais de Doentes de Esclerose Lateral Amiotrófica
Co-supervisor of João Cancela Lourenço da Silva Vitória
 Biologia (Other)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2020/02/01 - 2020/07/10 Análise computacional para a determinação de biomarcadores da Esclerose Lateral Amiotrófica
Co-supervisor of Beatriz Rodrigues Moreira da Silva
 Bioquímica (Degree)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2018/09/01 - 2019/07/18 Uncovering hidden patterns in biological datasets to identify metabolic alterations caused by an acute and sub-chronic DOX treatments
Co-supervisor of Rute Filipa do Carmo Pino
 Engenharia Biomédica (Master)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2019/02/01 - 2019/07/17 The role of ROS and membrane potential under the mitochondrial anchoring and trafficking: evaluation of mitochondrial parameters in a toxicology context using the human SH-SY5Y neuroblastoma cells
Supervisor of Diogo Lopes Carneiro
 Biologia (Degree)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2019/02/01 - 2019/07/02 Application of Data Mining and Machine Learning techniques for extraction of knowledge from metabolic datasets
Supervisor of Daniel Alexandre Rodrigues Ramalhão
 Bioquímica (Degree)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2014 - 2019/06/26 Pathophysiology of persistent doxorubicin cardiotoxicity: a mitochondrial-epigenetics link.
Co-supervisor of Luciana Carolina Lopes Ferreira
 Ciências Farmacêuticas (PhD)
Universidade de Coimbra, Portugal

Centro de Neurociências e Biologia Celular da Universidade de Coimbra, Portugal
2017/09 - 2018/09 Fetal liver mitochondria alterations in an ovine model of maternal obesity
Co-supervisor of Inês Maria Nogueira Cardoso
 Biologia Celular e Molecular (Master)
Universidade de Coimbra, Portugal

Centro de Neurociências e Biologia Celular da Universidade de Coimbra, Portugal
2018/02/01 - 2018/08/25 Mitochondrial and phenotypic characterization of SH-SY5Y cells differentiated through different experimental protocols
Supervisor of Sofia Orós Rodrigo
 Bioquímica (Degree)
Universidade de Coimbra, Portugal

Centro de Neurociências e Biologia Celular da Universidade de Coimbra, Portugal
2017/02/01 - 2017/07 Analysis of protein expression
Supervisor of Ana Micaela Barbosa de Sousa
 Bioquímica (Degree)
Universidade de Coimbra, Portugal

Centro de Neurociências e Biologia Celular da Universidade de Coimbra, Portugal
2017/02 - 2017/07 Optimization of assays to evaluate mitochondrial function and oxidative stress in biological samples
Supervisor of Juliana Paula da Costa Dinis de Oliveira
 Bioquímica (Degree)
Universidade de Coimbra, Portugal

Centro de Neurociências e Biologia Celular da Universidade de Coimbra, Portugal
2016/02/01 - 2016/07/08 High-Performance Liquid Chromatography applied to the quantification of adenine nucleotides
Supervisor of Cláudio Figueiredo Costa
 Bioquímica (Degree)
Universidade de Coimbra, Portugal

Centro de Neurociências e Biologia Celular da Universidade de Coimbra, Portugal
2016/02/01 - 2016/07/08 Optimization of high-throughput assays for respiratory chain enzymatic activities on isolated rat liver mitochondria
Supervisor of Inês Maria Nogueira Cardoso
 Bioquímica (Degree)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2016/02/01 - 2016/07/08 Transcriptional alterations associated to energetic remodelling in HepG2 cells.
Supervisor of Joana Rita Freitas Maleita
 Bioquímica (Degree)
Universidade de Coimbra, Portugal

Centro de Neurociências e Biologia Celular da Universidade de Coimbra, Portugal
2015 - 2016 Training in predictive mitochondrial toxicology
Co-supervisor of Tatiana Isabel Rodrigues Martins
 Estágio IEFP (Other)
Centro de Neurociências e Biologia Celular da Universidade de Coimbra, Portugal
2015/02/01 - 2015/07/17 Reverse Transcription qPCR: aplicação na determinação de diferenças de expressão genética
Supervisor of Nuno Miguel Beltrão Marques
 Bioquímica (Degree)
Universidade de Coimbra, Portugal

Centro de Neurociências e Biologia Celular da Universidade de Coimbra, Portugal
2014 - 2015/07/14 Pathophysiology of persistent doxorubicin cardiotoxicity : metabolic landscaping of the epigenome
Co-supervisor of André de Melo Ferreira
 Biologia Celular e Molecular (Master)
Universidade de Coimbra, Portugal

Centro de Neurociências e Biologia Celular da Universidade de Coimbra, Portugal
2013 - 2014/09/10 Berberine modulation on doxorubicin-induced cell death and autophagy
Co-supervisor of Tatiana Isabel Rodrigues Martins
 Bioquímica (Master)
Universidade de Coimbra, Portugal

Centro de Neurociências e Biologia Celular da Universidade de Coimbra, Portugal
2014/02/01 - 2014/07/06 Doxorubicin: Toxicity and persistent alterations of mitochondrial-relevant transcripts on H9C2 cardiomyoblasts and on cardiac tissue from sub-chronically-treated Wistar rats
Supervisor of Ana Sofia Moreira
 Bioquímica (Degree)
Universidade de Coimbra, Portugal

Centro de Neurociências e Biologia Celular da Universidade de Coimbra, Portugal
2013/02/01 - 2013/06/04 Doxorubicin cardiotoxicity mechanism
Supervisor of Pedro Cunha
 Bioquímica (Degree)
Universidade de Coimbra, Portugal

Centro de Neurociências e Biologia Celular da Universidade de Coimbra, Portugal
2012 - 2012 Pyruvate dehydrogenase and mitochondrial function in Huntington's disease models - influence of histone deacetylase inhibitors
Co-supervisor of Joana Cristina Pedro Rodrigues
 Biologia Celular e Molecular (Master)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2011 - 2011 Efeitos da cocaína, morfina e sua combinação no perfil neuroquímico e na bioenergética mitocondrial de fígado e cérebro de rato
Co-supervisor of Lisbeth Elena de Sousa e Silva
 Ciências Forenses (Master)
Cooperativa de Ensino Superior Politecnico e Universitario, Portugal
2010 - 2010 Perfil Neuroquímico do Estriado de Roedores Submetidos a uma Administração Aguda de Cocaína e ou Morfina
Co-supervisor of Tiago Morais
 Biologia (Master)
Universidade de Coimbra, Portugal
2010 - 2010 Estágio do Gabinete de Saídas Profissionais da Universidade de Coimbra
Co-supervisor of Patrícia Guarino
 Biologia Celular (Other)
Universidade de Coimbra, Portugal
2010 - 2010 Espectroscopia de Raman e FTIR de opiáceos e cocaína: relação com neurotoxicidade no seu consumo combinado
Co-supervisor of Diogo Ferreirinha
 Bioquímica (Scientific initiation)
Universidade de Coimbra, Portugal
2009 - 2009 Neurotoxicity and neuroprotection in the human brain
Co-supervisor of Rui Traquete
 Bioquímica (Scientific initiation)
Universidade de Coimbra, Portugal
2008 - 2008 Biochemical study of cocaine opioid interactions
Co-supervisor of Rui Pedro Marques da Costa
 Bioquímica (Degree)
Universidade de Coimbra, Portugal
2008 - 2008 Speedball: Combinação (im)perfeita
Co-supervisor of Rita Salomé Gonçalves Machado
 Bioquímica (Scientific initiation)
Universidade de Coimbra, Portugal
2008 - 2008 Estágio do Gabinete de Saídas Profissionais da Universidade de Coimbra
Co-supervisor of Rita Salomé Gonçalves Machado
 Bioquímica (Other)
Universidade de Coimbra, Portugal

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2021/06/10 - 2021/06/11 ESCI 2021 Symposium 4- Bioinformatics and Machine Learning in Biomedicine (2021/06/10 - 2021/06/11)
Symposium (Co-organisor)
 ESCI- European Society for Clinical Investigation, Netherlands
2021/06/09 - 2021/06/09 ESCI 2021 Pre-meeting course on Bioinformatic Tools for Data Analysis (2021/06/09)
Workshop (President of the Organising Committee)
 ESCI- European Society for Clinical Investigation, Netherlands
2020/05/27 - 2020/05/29 Symposium 9-Bioinformatics and Computational Biology for Biomedicine focused on "Modelling and biological data analysis for applications in precision medicine"- https://esci.eu.com/ (2020/05/27 - 2020/05/29)
Conference (Other)
 ESCI- European Society for Clinical Investigation, Netherlands
2020/01/21 - 2020/01/21 MitoScreening Retreat 2020 @ Seminário Maior de Coimbra (2020/01/21 - 2020/01/21)
Workshop (President of the Organising Committee)
 Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2019/09/01 - 2019/09/06 2nd FEBS Advanced Course on: 'Oncometabolism: From Conceptual Knowledge to Clinical Applications' (https://oncometabolism2019.febsevents.org/) (2019/09/01 - 2019/09/06)
Workshop (Member of the Organising Committee)
 Federação das Sociedades Europeias de Bioquímica (FEBS), Portugal
2019/06/27 - 2019/06/27 MitoScreening- First year report. UC Biotech, Cantanhede, Portugal (2019/06/27)
Workshop (President of the Organising Committee)
 Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2019/06/07 - 2019/06/07 "Evolving Brain, Health and Lifestyle", CNC Auditorium, University of Coimbra, Portugal (2019/06/07)
Seminar (President of the Organising Committee)
 Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2019/05/22 - 2019/05/24 53rd Annual Meeting of the European Society for Clinical Investigation (https://esci2019.com/) (2019/05/22 - 2019/05/24)
Congress (Member of the Organising Committee)
 ESCI- European Society for Clinical Investigation, Netherlands
2019/05/22 - 2019/05/22 ESCI Pre-congress course on "Mitochondrial and cellular respirometry" (2019/05/22)
Workshop (Co-organisor)
 ESCI- European Society for Clinical Investigation, Netherlands
2019/01/22 - 2019/01/22 "MitoScreening- Progress Report and Brainstorming", UCBiotech, Cantanhede, Portugal (2019/01/22)
Workshop (President of the Organising Committee)
 Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2018/10/30 - 2018/10/30 "Hands-on workshop in Machine Learning with Python", presented by Nuno Lourenço, UCBiotech, Cantanhede, Portugal (2018/10/30 - 2018/10/30)
Workshop (President of the Organising Committee)
 Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2018/07/20 - 2018/07/20 "MitoScreening- Kick-off meeting", held at the Department of Computer Sciences, University of Coimbra, Portugal (2018/07/20)
Workshop (President of the Organising Committee)
 Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2017/06/18 - 2017/06/24 FEBS Advanced Lecture Course on Oncometabolism: From Conceptual Knowledge to Clinical Applications. The course addressed topics related to oncometabolism, since the basic concepts until the more advanced clinical applications. (2017/06/18 - 2017/06/24)
Other (Member of the Organising Committee)
 Federação das Sociedades Europeias de Bioquímica (FEBS), Portugal
2016/04/11 - 2016/04/15 Cell Respirometry: Basics and Applications (http://www1.biocant.pt/cell_respirometry_basics_and_aplications) (2016/04/11 - 2016/04/15)
Workshop
 Centro de Neurociências e Biologia Celular da Universidade de Coimbra, Portugal
2014/12/17 - 2015/12/20 XVIII Portuguese Biochemistry Congress (2014/12/17 - 2014/12/20)
Congress (Member of the Organising Committee)
 Sociedade Portuguesa de Bioquímica, Portugal
2015/02/02 - 2015/02/03 Cancer Epigenetics and Metabolism: Connecting the Dots (http://www1.biocant.pt/cancer_epigenetics_metabolism/) (2015/02/02 - 2015/02/03)
Congress (Member of the Organising Committee)
 Centro de Neurociências e Biologia Celular da Universidade de Coimbra, Portugal
2013 - 2013 47th Annual Scientific Meeting of the European Society for Clinical Investigation
Congress (Other)
 European Society of Clinical Investigation, Portugal
2008/03/10 - 2008/03/16 Exhibition entitled "The brain: where, how and what for" (http://goo.gl/QhmH7m, project 19) Integrated in the Brain Awareness Week 2008. Held at Coimbra Science Museum, University of Coimbra, Portugal Funded by the Federation of European Neuroscience Societies (2008/03/10 - 2008/03/16)
Exhibition (President of the Organising Committee)
 Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2018/09/26 - 2018/09/27 COSMETORIUM 2018 (https://www.cosmetorium.es/)
Congress
 Cosmetorium 2018
Sociedad Espanola de Quimicos Cosmeticos, Spain
2017/09/04 - 2017/09/14 Summer School in Computational Biology (https://www.uc.pt/en/iii/initiatives/cbuc)
Workshop
 2017 Summer School in Computational Biology
Universidade de Coimbra, Portugal
2015/02/18 - 2015/03/20 ineoStart 2015: Business Acceleration and Innovation Programme (https://start.ineo.pt/)
Workshop
 ineoStart 2015
Universidade de Coimbra- Instituto Pedro Nunes, Portugal

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2021/07/21 Avaliação do potencial citotóxico e citoprotetor do óleo essencial de Tomilho Bela-luz (Thymus mastichina) em células HepG2
Supervisor
 Rafael Alexandre Ferreira (Other)
Instituto Politécnico de Coimbra Escola Superior Agrária de Coimbra, Portugal
2021/07/20 Neuronal mitochondrial metabolism and dynamic profiling under physiological and pathological conditions using biological- based machine learning approaches
Supervisor
 Rui Fernando Vieira Lisboa Matias Simões (PhD)
Universidade de Coimbra Instituto de Investigacao Interdisciplinar, Portugal
2021/06/07 Neurotoxicity of synthetic cathinones
(Thesis) Main arguer
 Jorge Emanuel Miranda Teixeira Soares (PhD)
Universidade do Porto Faculdade de Medicina, Portugal
2020/12/16 Modulation of the Proteostasis Network and Energy Metabolism in Huntington’s Disease
(Thesis) Main arguer
 Tânia Raquel Pereira Soares (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2020/12/09 Impact of Rebaudioside A in cancer cell metabolism: Potential as a safe chemotherapeutic adjuvant
Supervisor
 Gonçalo José Martins Afonso (Master)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2020/12/03 Effects of Extended Passaging on the BEAS-2B Cell Line, an In Vitro Model of Human Lung Epithelium Established for the Study of Lung Carcinogenesis
Supervisor
 Margarida Conceição Moreira Sobral (Master)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2020/07/27 Mitochondrial pyruvate carrier inhibition as a potential approach to mitigate neurodegeneration: insights for Huntington's disease - Seminário de Doutoramento
(Thesis) Main arguer
 Ângela Daniela Abreu Oliveira (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2020/07/24 Evaluation of cytotoxic and cytoprotective potential of Helichrysum italicum essential oil in HepG2 cells (Avaliação do potencial citotóxico e citoprotetor do óleo essencial de Helichrysum italicum em células HepG2)
Supervisor
 Susana Raquel Tiago Nogueira (Other)
Instituto Politécnico de Coimbra Escola Superior Agrária de Coimbra, Portugal
2019/12/10 Alterations in mitochondrial biogenesis and regulation of morphology in lymphoblasts from Amyotrophic Lateral Sclerosis patients
(Thesis) Main arguer
 Marcelo Filipe Brito Carvalho (Other)
Instituto Politécnico de Coimbra Escola Superior Agrária de Coimbra, Portugal
2019/09/16 Mitochondria-based screening of drug neurotoxicity in differentiated SH-SY5Y cells
Supervisor
 Rafaela Margarida Cura Ferrão (Master)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2018/12/04 Bioenergetics failure in human drug addiction
(Thesis) Main arguer
 Vanessa Filipa Rodrigues Costa (Other)
Instituto Politécnico de Coimbra Escola Superior Agrária de Coimbra, Portugal
2018/09/21 Experimental enhancement of cellular OXPHOS reliance for mitochondrial health assessments - Development and characterization of a rapid and efficient method to induce OXPHOS in skin fibroblasts, for the assessment of mitochondrial toxicity and protection.
Supervisor
 Cláudio Figueiredo Costa (Master)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2012 Pyruvate dehydrogenase and mitochondrial function in Huntington's disease models - influence of histone deacetylase inhibitors (http://hdl.handle.net/10316/26028)
Supervisor
 Joana Cristina Pedro Rodrigues (Master)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2011/09/29 Efeitos da cocaína, morfina e sua combinação na bioenergética mitocondrial do fígado (http://hdl.handle.net/20.500.11816/116)
Supervisor
 Lisbeth Elena Sousa e Silva (Master)
Cooperativa de Ensino Superior Politecnico e Universitario, Portugal
2011 Methamphetamine induces microglial cell death: protective effect of Interleukin-6 Vanessa Filipa Coelho Santos (Master)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2010 Efeitos do peptídeo beta-amilóide no hipotálamo. Protecção por hormonas metabólicas.
(Thesis) Main arguer
 Sílvia Catarina Fernandes Gomes (Master)
Universidade de Coimbra, Portugal
2008 Biochemical study of cocaine opioid interactions Rui Pedro Marques da Costa (Other)
Universidade de Coimbra, Portugal

Interview (tv / radio show)

Program Topic
2014/11/10 - 2014/11/10 SIC Telejornal Efeitos das drogas no cérebro
Distinctions

Award

2020 Best communication at the Bioinformatics Symposium
ESCI- European Society for Clinical Investigation, Netherlands
2003 Best poster at FEBS course (Greece)
Federação das Sociedades Europeias de Bioquímica (FEBS), Portugal
2002 Best poster at St Petersburg (Russia)
International Symposium on "Reactive oxygen and nitrogen species: diagnostic, preventive and therapeutic values", Russia

Other distinction

2008 Brain Awareness Week Funding
Federation of European Neuroscience Societies, Belgium
2005 Travel fellowship- YTF
Federação das Sociedades Europeias de Bioquímica (FEBS), Portugal
2005 Travel fellowship FLAD
Fundação Luso-Americana, Portugal
2005 Travel fellowship- Gulbenkian Foundation
Fundação Calouste Gulbenkian, Portugal
2004 Travel fellowship- NATO
NATO, Belgium
2004 Travel fellowship- SPN
Sociedade Portuguesa de Neurociências, Portugal
2003 Travel fellowship- YTF
Federação das Sociedades Europeias de Bioquímica (FEBS), Portugal
2002 Travel fellowship- SPB
Sociedade Portuguesa de Bioquímica, Portugal
2001 Travel fellowship- YTF
Federação das Sociedades Europeias de Bioquímica (FEBS), Portugal