Rui Gonçalo Teixeira da Silva (8115-4B77-155D)

Curriculum Vitae

Rui Gonçalo Teixeira da Silva

Rui Gonçalo Teixeira da Silva. Concluiu o Mestrado em Mestrado em Bioquímica em 2014 pela Universidade de Coimbra Faculdade de Ciências e Tecnologia e Licenciatura em Licenciatura em Bioquímica em 2012 pela Universidade de Coimbra Faculdade de Ciências e Tecnologia. Actualmente, é PhD Student no Institut d'Investigacions Biomèdiques de Barcelona.

Identification

Personal identification

Full name: Rui Gonçalo Teixeira da Silva

Citation names

Silva, Rui

Author identifiers

Ciência ID: 8115-4B77-155D
ORCID iD: 0000-0001-7274-4007

Languages

Language	Speaking	Reading	Writing	Listening	Peer-review
English	Proficiency (C2)	Proficiency (C2)	Proficiency (C2)	Proficiency (C2)	Proficiency (C2)
Spanish; Castilian	Intermediate (B1)	Intermediate (B1)	Elementary (A2)	Elementary (A2)	Elementary (A2)

Education

	Degree	Classification
2014 Concluded	Mestrado em Bioquímica (Mestrado) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal "The effect of silver nanoparticles: a chronic in vivo study for the evaluation of hepatic mitochondrial toxicity" (THESIS/DISSERTATION)	17
2012 Concluded	Licenciatura em Bioquímica (Licenciatura) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal "Risk Assessment and Ecological Sustainability of Cork Oak in Montado ecosystems" (THESIS/DISSERTATION)	15

Affiliation

Others

	Category Host institution	Employer
2018/11 - Current	PhD Student	Institut d'Investigacions Biomèdiques de Barcelona, Spain

2017/11/01 - 2018/10/01	Bolsa de Mestre	CNC.IBILI, Portugal

2016/03/01 - 2017/10/31	Marie Curie Fellow (Laboratório do Professor Maurizio Crestani); Projecto sobre epigenética e metabolismo energético do tecido adiposo	Università degli Studi di Milano Dipartimento di Scienze Farmacologiche e Biomolecolari, Italy

2015/04/01 - 2015/07/01	Visiting Research Student (Laboratório do Professor Richard Porter), ao abrigo do programa ERASMUS PLUS; Projecto sobre metabolismo energético das plaquetas.	Trinity Biomedical Sciences Institute, Ireland

Outputs

Publications

Book chapter	Silva, Rui. "Biomarkers of Mitochondrial Dysfunction and Toxicity". 2019. 10.1016/b978-0-12-814655-2.00055-4
Conference paper	Teodoro, João S.; Amorim, João A.; Silva, Rui; Rolo, Anabela P.; Steegborn, Clemens; Sinclair, David A.; Palmeira, Carlos M.. "Sirtuin- cAMP crosstalk in metabolic diseases: nucleus versus mitochondria". 2018. 10.1016/j.freeradbiomed.2018.04.526
Journal article	"Liver Graft Hypothermic Static and Oxygenated Perfusion (HOPE) Strategies: A Mitochondrial Crossroads". International Journal of Molecular Sciences 23 10 (2022): 5742-5742. http://dx.doi.org/10.3390/ijms23105742. 10.3390/ijms23105742 Teodoro, J.S.; Rui Silva; Ivo Ferreira Machado; Arnau Panisello-Roselló; Joan Roselló-Catafau; Anabela P. Rolo; Carlos M. Palmeira. "Shaping of Hepatic Ischemia/Reperfusion Events: The Crucial Role of Mitochondria". Cells (2022): https://www.mdpi.com/2073-4409/11/4/688. 10.3390/cells11040688 Rui Silva; Ivo Ferreira Machado; Teodoro, J.S.; Arnau Panisello-Roselló; Joan Roselló-Catafau; Anabela P. Rolo; Carlos M. Palmeira. "PEG35 as a Preconditioning Agent against Hypoxia/Reoxygenation Injury". International Journal of Molecular Sciences (2022): https://www.mdpi.com/1422-0067/23/3/1156. 10.3390/ijms23031156 "IGL-2 as a Unique Solution for Cold Static Preservation and Machine Perfusion in Liver and Mitochondrial Protection". Transplantation Proceedings (2021): http://dx.doi.org/10.1016/j.transproceed.2021.10.008. 10.1016/j.transproceed.2021.10.008 "Role of PEG35, Mitochondrial ALDH2, and Glutathione in Cold Fatty Liver Graft Preservation: An IGL-2 Approach". International Journal of Molecular Sciences 22 10 (2021): 5332-5332. http://dx.doi.org/10.3390/ijms22105332. 10.3390/ijms22105332 "Glycocalyx as a Useful Marker of Endothelial Injury in Liver Transplantation: The Role of Preservation Solution". Transplantation 104 12 (2020): e356-e357. http://dx.doi.org/10.1097/tp.0000000000003380. 10.1097/tp.0000000000003380 "Polyethylene Glycol 35 as a Perfusate Additive for Mitochondrial and Glycocalyx Protection in HOPE Liver Preservation". International Journal of Molecular Sciences (2020): http://dx.doi.org/10.3390/ijms21165703. 10.3390/ijms21165703 "Exploration of the cellular effects of the high-dose, long-term exposure to coffee roasting product furan and its by-product cis-2-butene-1,4-dial on human and rat hepatocytes". Toxicology Mechanisms and Methods (2020): http://dx.doi.org/10.1080/15376516.2020.1780361. 10.1080/15376516.2020.1780361 Ferrari, A.; Longo, R.; Silva, R.; Mitro, N.; Caruso, D.; De Fabiani, E.; Crestani, M.. "Epigenome modifiers and metabolic rewiring: New frontiers in therapeutics". Pharmacology and Therapeutics 193 (2019): 178-193. http://www.scopus.com/inward/record.url?eid=2-s2.0-85053330339&partnerID=MN8TOARS. 10.1016/j.pharmthera.2018.08.008 Longo, R.; Ferrari, A.; Fiorino, E.; Mitro, N.; Cermenati, G.; Silva, R.; Caruso, D.; et al. "Epigenetic regulation of white adipose tissue physiology: Histone deacetylase 3 as a key molecular switch of white adipose tissue metabolism and browning". Atherosclerosis 275 (2018): e14. http://dx.doi.org/10.1016/j.atherosclerosis.2018.06.924. 10.1016/j.atherosclerosis.2018.06.924 Ferrari, A.; Longo, R.; Fiorino, E.; Silva, R.; Mitro, N.; Cermenati, G.; Gilardi, F.; et al. "HDAC3 is a molecular brake of the metabolic switch supporting white adipose tissue browning". Nature Communications 8 1 (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85025464997&partnerID=MN8TOARS. 10.1038/s41467-017-00182-7 Teodoro, J.S.; Silva, R.; Varela, A.T.; Duarte, F.V.; Rolo, A.P.; Hussain, S.; Palmeira, C.M.. "Low-dose, subchronic exposure to silver nanoparticles causes mitochondrial alterations in Sprague-Dawley rats". Nanomedicine 11 11 (2016): 1359-1375. http://www.scopus.com/inward/record.url?eid=2-s2.0-84971483351&partnerID=MN8TOARS. 10.2217/nnm-2016-0049
Thesis / Dissertation	Silva, Rui. "The effect of silver nanoparticles: a chronic in vivo study for the evaluation of hepatic mitochondrial toxicity". Master, Universidade de Coimbra Faculdade de Ciencias e Tecnologia, 2014. http://hdl.handle.net/10316/28174.

Activities

Oral presentation

	Presentation title	Event name Host (Event location)
2020/09/20	ALDH2/4-HNE Balance During Cold Storage Of Fatty Liver Grafts Is Modulated By Polyethylene Glycol 35	ESCI Virtual Meeting 2020
2019/05/08	Role of aldehyde dehydrogenase 2 in fatty liver preservation	7th EASD NAFLD STUDY GROUP MEETING, NAFLD/NASH Progression (Lisboa, Portugal)
2018/10/21	Subchronic in vivo study for the evaluation of hepatic mitochondrial toxicity induced by silver nanoparticles	11th MitoEAGLE Training School - MiPschool 2018 (Tromso-Bergen, Norway)
2017/10/19	High Fat Diet suppresses the effect of Hdac3 ablation in HDAC3 KO mice	Congresso SISA Sezione Regionale Lombardia (Milão, Italy)
2017/07/29	Epigenetic Regulation of Subcutaneous Adipose Tissue Metabolism	Next Step VII Department of Pharmacological and Biomolecular Sciences (DiSFeB), University of Milan. (Milão, Italy)
2016/07/11	Histone Deacetylase 3 regulates the enhancer activity of key target genes on white adipose tissue browning	Next Step VI Department of Pharmacological and Biomolecular Sciences (DiSFeB), University of Milan (Milão, Italy)