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Maria Luísa Teixeira de Azevedo Rodrigues Corvo. Completed the Licenciatura in Química in 1986 by Faculdade de Ciências, Universidade de Lisboa and Doctor in Ciências da Saúde (Farmácia, Tecnologia Farmacêutica) in 1998 by Universiteit Utrecht. Is Principal Researcher with Habilitation in Faculdade de Farmácia, Universidade de Lisboa and integrated researcher at iMed.ULisboa (Drug Delivery & Immunoengineering Group - BioNanoScience). Has been working on the development of lipidic drug carrier nanosystems for the delivery anti-inflammatory or cancer drugs (small molecular weight to biopharmaceutics including enzymes). Systems developed and optimized were liposomes (attractive delivery systems) for the treatment and/or visualization of inflammatory diseases (ex. Rheumatoid Arthritis, Ischaemia/Reperfusion Injury, Inflammatory bowel diseases, diabetes) and cancer (ex: leukaemia, colorectal or lung carcinoma). The systems were developed to be administered parenteral via (SC, IV) or inhalation (DPI). Corvo has also been studying mechanisms of action of developed formulation and their correlation with biomarkers, tissue disposition and pharmacokinetics. Published 66 articles in journals, 7 books chapter and edited 1 book. Has participated as invited speaker in 18 scientific events and as selected oral comunications team in 21 congresses. Supervised 3 PhD thesis(es) and co-supervised 2. Supervised 21 MSc dissertation(s). Has received 3 awards and/or honors. Participated as Principal investigator in 7 project(s) and Researcher in 19 project(s). In his curriculum Ciência Vitae the most frequent terms in the context of scientific, technological and artistic-cultural output are: Liposomes; Spay drying; Ultrasonic nozzle; Two-flid nozzle; Dry powder inhalers; Nasal dry powder formulations; toxicity; cholesterol; antioxidant; anti-inflammatory; Leishmaniasis; Dinitroanilines; Liposomes; Immune response; Microalgae; Functional Ingredients; Toxicology; Rheology and Microstructure ; Biopharmaceuticals; Drying technologies; Solid dosage forms; Supercritical carbon dioxide; Supercritical carbon dioxide-assisted spray-drying; Sustainable engineering; Analytical Chemistry; Chemistry (miscellaneous); Molecular Medicine; Pharmaceutical Science; Drug Discovery; Physical and Theoretical Chemistry; Organic Chemistry; Active targeting; Drug delivery nanosystems; Passive targeting; Rheumatoid arthritis; Quercetin; Supercritical CO2- assisted spray drying; Vaccines; Adjuvants; Nanotechnology; Immunotherapy; Melanoma Brain Metastases; metabolic profiling and metabonomics; silver nanoparticles; toxicological and biological effects; nanotoxicology; Drug Discovery and Design; Drug Development and Use; Molecular Diagnostics; Long circulating liposomes; Small cell lung cancer; Antagonist G; Ischemia and Reperfusion Injury; Liver; Anti-inflammatory; Dry powder inhaler; Carrier-free formulation; Praticle engineering; Spray-drying; Active pharmaceutical ingredient; Teses de mestrado - 2020; Spray freeze-drying; Mechanical stability; Sugars; Polyethylene glycol; Arabic gum; Hepatic ischemia-reperfusion (IR); Aquaporins (AQPs); Ischemia stimulus; Inflammation stimulus; Liposomal drug formulations; Cytokines expression; Inflammation resolution; dry powder inhaler; lung dissolution; pulmonary drug delivery; in vitro dissolution method; carrier-based formulation; carrier-free formulation; Phenylalanine hydroxylase; Phenylketonuria; Enzyme reposition.
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Identification

Personal identification

Full name
Maria Luísa Teixeira de Azevedo Rodrigues Corvo

Citation names

  • Corvo, M. Luisa
  • Corvo, Maria Luisa

Author identifiers

Ciência ID
8215-7B2A-AECE
ORCID iD
0000-0002-6332-3937
Google Scholar ID
https://scholar.google.pt/citations?user=mSCDQCoAAAAJ&hl=pt-PT
Researcher Id
A-8333-2012
Scopus Author Id
6602470716

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
French Advanced (C1) Advanced (C1) Intermediate (B1) Advanced (C1)
English Intermediate (B1) Advanced (C1) Intermediate (B1) Intermediate (B1)
Spanish; Castilian Intermediate (B1) Intermediate (B1) Beginner (A1) Intermediate (B1)
Education
Degree Classification
2023/01/09
Concluded
 Farmácia, especialidade de Tecnologia Farmacêutica (Título de Agregado)
Universidade de Lisboa Faculdade de Farmácia, Portugal
1998/12/07
Concluded
 Ciências da Saúde (Doctor)
Major in Tecnologia Farmacêutica
Universiteit Utrecht, Netherlands
1986/10
Concluded
 Química (Licenciatura)
Major in Ramo Cientifico área Orgânica e Bioquímica
Faculdade de Ciências, Universidade de Lisboa, Portugal
 16/20
Affiliation

Science

Category
Host institution 		Employer
2000/04/21 - 2009/12/31 Auxiliary Researcher (Research) INETI, Portugal
1997/05/23 - 2008/12/31 Research Assistant (Research) INETI, Portugal

Teaching in Higher Education

Category
Host institution 		Employer
2013 - Current Invited Assistant Professor (University Teacher) Universidade de Lisboa Faculdade de Ciências, Portugal
2018 - 2019 Invited Assistant Professor (University Teacher) Universidade de Lisboa, Portugal
2016 - 2017 Assistant Professor (University Teacher) Universidade de Lisboa, Portugal
2015 - 2016 Assistant Professor (University Teacher) Universidade de Lisboa Faculdade de Farmácia, Portugal
2013 - 2016 Assistant Professor (University Teacher) Universidade de Lisboa Faculdade de Ciências, Portugal

Others

Category
Host institution 		Employer
2023/11 - Current Principal Researcher Universidade de Lisboa Faculdade de Farmácia, Portugal
2018/12/01 - Current Vice-Dean Universidade de Lisboa Faculdade de Farmácia, Portugal
Universidade de Lisboa Faculdade de Farmácia, Portugal
2009/01/01 - 2023/11 Auxiliar Research Universidade de Lisboa Faculdade de Farmácia, Portugal
Universidade de Lisboa Faculdade de Farmácia, Portugal
1994/10/01 - 1998/12/07 PhD Student Universiteit Utrecht, Netherlands
1989/11/01 - 1997/05/23 Superior technician INETI, Portugal
1986/05/01 - 1989/11/01 Grant Student INETI, Portugal
Projects

Grant

Designation Funders
2018/10 - 2021/09 Programming the type and localization of adaptive immunity by targeting TLR2: a strategy for the development of novel veterinary vaccines
PTDC/CVT-CVT/31840/2017
Researcher
Governo da República Portuguesa Ministério da Ciência Tecnologia e Ensino Superior
2012/03 - 2015/09 TherMelVac- dendritic cell-targeted peptide vaccine against melanoma by ligand-modified nanoparticles
grant.Provided by PTCRIS: 119389
PTDC/SAU-FAR/119389/2010
Researcher
Universidade de Lisboa Faculdade de Farmácia, Portugal

Université catholique de Louvain, Belgium

Migal Galilee Technology Center, Israel
Fundação para a Ciência e a Tecnologia
Concluded
2011 - 2012 Effect of Superoxide dismutase enzymosomes admistration in the reperfusion injury in the liver. An animal model study
Bolsa de Investigação SPT/ Astellas
Principal investigator
Universidade de Lisboa Faculdade de Farmácia, Portugal
Concluded
2005/07 - 2007/12 Microtubule inhibitor formulations against zoonotic visceral leishmaniasis
grant.Provided by PTCRIS: 56995
grant.Provided by PTCRIS: 82489
POCI/CVT/56995/2004
Researcher
Universidade de Lisboa Faculdade de Farmácia, Portugal

Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal

Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2002 - 2005 Enzimossomas de Superóxido Dismutase para o Tratamento de Doenças Inflamatórias e de Isquémia-reperfusão
POCTI/42259/FCB/2001
Principal investigator
Governo da República Portuguesa Ministério da Ciência Tecnologia e Ensino Superior

Contract

Designation Funders
2022/01/17 - 2025/01/16 Multifunctional nano-immunotherapy for melanoma brain metastases treatment
PTDC/BTM-SAL/4350/2021
Researcher
Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal

Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2022/01/01 - 2024/12/31 Targeting TLR2 for improved veterinary vaccines
PTDC/CVT-CVT/4599/2021
Researcher
Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal

Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal

Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2017 - 2020 Targeted liposomal antioxidant and anti-inflammatory therapy for liver ischemic reperfusion injury
PRC
Principal investigator
Universidade de Lisboa Faculdade de Farmácia, Portugal
Concluded
2015 - 2020 BioPharmaceutical Dry Powser Inhaler Formulations
PhD program
Principal investigator
Universidade de Lisboa Faculdade de Farmácia, Portugal
 Hovione
Ongoing
2015 - 2020 Dissolution of Dry Powder Inhaler formulations: in vitro/in vivo correlation
PhD Program
Principal investigator
Universidade de Lisboa Faculdade de Farmácia, Portugal
Ongoing
2019/01/01 - 2019/12/31 Research Institute for Medicines
UID/DTP/04138/2019
Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal

Instituto Politécnico de Coimbra Centro de Estudos de Recursos Naturais Ambiente e Sociedade, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2017 - 2019 Translational proof of concept of spintronic micro-nanoparticle non thermal vibrational therapy for glioblastomas.
ENMed/0036/2016
Researcher
Governo da República Portuguesa Ministério da Ciência Tecnologia e Ensino Superior
2016 - 2019 Sphingolipid organization in the plasma membrane of Saccharomyces cerevisiae. Implication in antifungal mode of action and fungal resistance
PTDC/BBB-BQB/6071/2014
Researcher
Ministério da Ciência, Tecnologia e Inovação
2012/04/16 - 2015/09/30 Metabolic profiling: a novel tool for evaluation of the toxicological and biological effects of nanomaterials
PTDC/SAU-TOX/120953/2010
Provided by PTCRIS: 120953
Researcher
Universidade de Aveiro, Portugal

Universidade de Aveiro CICECO, Portugal

Universidade de Lisboa Faculdade de Farmácia, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2014 - 2015 Arroz+ - Novarroz, Produtos Alimentares SA - A4 - Avaliação (in vivo) do potencial de redução colesterol, da capacidade antioxidante e anti-inflamatória do farelo desengordurado
QREN I&DT Co-Promoção nº38749
Principal investigator
Agência Nacional de Inovação SA
Concluded
2011/01/01 - 2013/12/31 Strategic Project - UI 4013 - 2011-2012
PEst-OE/SAU/UI4013/2011
Universidade de Lisboa Faculdade de Farmácia, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2007/06/01 - 2010/11/30 PIGMENTS, ANTIOXIDANTS AND PUFA'S IN MICROALGAE-BASED FOOD PRODUCTS - FUNCTIONAL AND STRUCTURAL IMPLICATIONS
PTDC/AGR-ALI/65926/2006
Researcher
Universidade de Lisboa Instituto Superior de Agronomia, Portugal

Instituto Português do Mar e da Atmosfera, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Book
  1. ML Corvo. Enzimas em Biotecnologia: produção, aplicações e mercado. Brazil. 2008.
Book chapter
  1. Rocha, Sonia; Corvo, M. Luisa; Eduarda Fernandes; Freitas, Marisa. "Novel Strategies for Managing Diabetes mellitus Using Lipid-Based Delivery Systems as Vehicles of Polyphenols". In Principles and Practices of Novel Drug Delivery Systems. 2023.
    Accepted
  2. Daniela Ribeiro; Marisa Freitas; José Miguel P. Ferreira de Oliveira; Corvo, M. Luisa; Félix Dias Carvalho; Eduarda Fernandes. "Inflammatory Pathways and In Vivo Studies of Inflammatory Bowel Disease". 1-23. IGI Global, 2021.
    10.4018/978-1-7998-3580-6.ch001
  3. Marisa Freitas; José Miguel Pimenta Ferreira de Oliveira; Corvo, M. Luisa; Félix Dias Carvalho; Eduarda Fernandes; Daniela Ribeiro. "Insights on the Potential Preventive and Healing Effects of Flavonoids in Inflammatory Bowel Disease". In Diagnostic and Treatment Methods for Ulcerative Colitis and Colitis, 38-66. Hershey, United States: IGI Global, 2021.
    Published • 10.4018/978-1-7998-3580-6.ch003
  4. Praça, F.S.G.; Marinho, H.S.; Martins, M.B.F.; Gaspar, R.; Corvo, M. Luisa; Medina, W.S.G.; Pra¿a, F. S.; et al. "Current aspects of breast cancer therapy and diagnosis based on a nanocarrier approach". 2017.
  5. Florindo, H.F.; Lopes, J.; Silva, L.C.; Martins, M.B.; Gaspar, R.; Florindo, H. F.; Silva, L. C.; Corvo, M. Luisa; Martins, M. B.. "Regulatory Development of Nanotechnology-Based Vaccines". In Diagnostic and Treatment Methods for Ulcerative Colitis and Colitis. 2017.
  6. Susana Marinho, H.; Martins, M.B.F.; Corvo, M. Luisa. Corresponding author: Corvo, M. Luisa. "Nanomedicines as a strategy for the therapeutic use of superoxide dismutases". In Diagnostic and Treatment Methods for Ulcerative Colitis and Colitis, 135-170. New York, United States: Nova Science Publisher's, Inc. - Nova Biomedical, 2016.
    Published
  7. Gaspar, RogérioS; Florindo, HelenaF; Silva, LianaC; Videira, MafaldaA; Corvo, M. Luisa; Martins, BárbaraF; Silva-Lima, Beatriz. "Regulatory Aspects of Oncologicals: Nanosystems Main Challenges". edited by Alonso, Maria José; Garcia-Fuentes, Marcos, 425-452. 2014.
    10.1007/978-3-319-08084-0_15
  8. Cruz, M. E. M.; Simoes, S. I. D.; Corvo, M. Luisa; Martins, M. B. F.; Gaspar, M. M.. "Formulation of Nanoparticulate Drug Delivery Systems (NPDDS) for Macromolecules". edited by Pathak, Y.; Thassu, D., 35-49. 2009.
  9. Cruz, Maria Eugénia Meirinhos; Sandra Isabel Dias Simões; Corvo, Maria Luisa ; Martins, Maria Bárbara; Gaspar, Maria Manuela. "Formulation of NPDDS for Macromolecules". 35-49. Informa Healthcare., Taylor & Francis Group, 2009.
  10. Cruz, Maria Eugénia; Almeida, António; Corvo, Maria Luisa. "Sistemas de libertação controlada de fármacos". In Biotecnologia: Fundamentos e Aplicações, 359-376. Lisboa, Portugal: Lidel - Edições Técnicas, 2003.
    Published
Conference abstract
  1. Santos, Telma C.; Matos, Cristina P.; Santos, Filipa C.; Corvo, M. Luisa; Garcia, M. Helena; Tomaz, A. I.; DE ALMEIDA, RODRIGO F.M.. "Interaction of new active Ruthenium anticancer agents with lipid bilayers". Paper presented in EBSA 2013, Lisboa, 2013.
    Published
Conference paper
  1. Duarte, Í.; Serôdio, P.; Corvo, M.L.; Vicente, J.; Pinto, J.F.; Temtem, M.; Duarte, I.. "Production of amorphous nano-solid dispersions using a solvent controlled precipitation process - Benchmarking with the spray drying process". 2015.
  2. Vera Moura; Manuela Lacerda; Paulo Figueiredo; Corvo, M. Luisa; Maria M E Cruz; Raquel Soares; Sérgio Simões; João Moreira. "Abstract 4521: A novel targeted triggered release nanoparticle against cancer cells of diverse histological origin.". 2013.
    10.1158/1538-7445.AM2013-4521
  3. Moura, Vera; Lacerda, Manuela; Figueiredo, Paulo; Corvo, M. Luisa; Cruz, M. Eugenia M.; Soares, Raquel; de Lima, M. Conceicao Pedroso; Simoes, Sergio; Moreira, Joao Nuno. "Limiting tumor invasion with multifunctional nanoparticle targeting the tumor microenvironment.". Paper presented in AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, San Francisco, CA, 2011.
    10.1158/1535-7163.targ-11-c233
  4. Moura, Vera; Lacerda, Manuela; Figueiredo, Paulo; Corvo, M. Luisa; Cruz, ME; Maria C. Pedroso de Lima; Simões, Sérgio; Moreira, João Nuno. "Targeting non-viral vectors to tumor cells and the tumor micronvironment.". Paper presented in The 16th International Charles Heidelberger Symposium on Cancer Research, Coimbra, 2010.
    Published
  5. Vale, C.A.; Corvo, M.L.; Martins, L.C.D.; Marques, C.R.; Storm, G.; Cruz, M.E.M.; Martins, M.B.F.. "Construction of enzymosomes: Optimization of coupling parameters". 2006.
  6. Cruz, M.E.M.; Martins, M.B.; Corvo, M. Luisa; Jorge, J.C.S.; Gaspar, M.M.. "Native and lipophilic derivatives of asparaginase and superoxide dismutase and respective liposomal forms". 1994.
Conference poster
  1. Sónia Rocha; Carina Proença; Artur M. S. Silva; Corvo, M. Luisa; Eduarda Fernandes; Freitas, Marisa. Corresponding author: Freitas, Marisa. "Targeting hepatic glucose and glycogen metabolism with chromone derivatives.". Paper presented in IDF World Diabetes Congress 2022, 2022.
  2. Ferreira-Silva, Margarida; Faria-Silva, C.; Carvalheiro, Manuela; Simões, Sandra; Fernandes, Eduarda; Baptista, Pedro; Alexandra R Fernandes; Corvo, M. Luisa. "Quercetin liposomes for hepatic ischemia and reperfusion injury a promising therapeutic approach". Paper presented in First Symposium on Advanced Technologies on Drug Delivery, 2021.
  3. silvestre, Rafaela; Godinho-Pereira, Joana; Dionisio Lopes, Margarida; Figueira, Inês; Carvalheiro, Manuela Colla; Corvo, M. Luisa; Maria Alexandra de Oliveira Silva Braga Pedreira de Brito. "Boosting the blood-brain barrier: a novel approach for preventing breast cancer brain metastases.". 2021.
  4. Silvestre, Rafaela; Dionisio Lopes, Margarida; Godinho-Pereira, Joana; Figueira, Inês; Carvalheiro, Manuela Colla; Corvo, M. Luisa; Maria Alexandra de Oliveira Silva Braga Pedreira de Brito. "Boosting the blood-brain barrier: a way to prevent breast cancer brain metastases". Paper presented in imed Meeting 2021, 2021.
  5. Sónia Rocha; Mariana Lucas; Vera L. M. Silva; Artur M. S. Silva; Alberto Nova Araújo; Corvo, M. Luisa; Eduarda Fernandes; et al. "The effect of pyrazoles on the emerging diabetic therapeutic targets: Protein Tyrosine Phosphatase 1b and Glycogen Phosphorylase". Paper presented in Interfacing Chemical Biology and Drug Discovery - 56th International Conference on Medicinal Chemistry, 2021.
  6. Sónia Rocha; Daniela Ribeiro; Vera L. M. Silva; Pedro M. O. Gomes; Artur M.S. Silva; Alberto Nova Araújo; M Luisa Corvo; et al. Corresponding author: Marisa Freitas. "Insight into the protein tyrosine phosphatase 1B (PTP1B) inhibitory activity of pyrazoles". Paper presented in 6th International Electronic Conference on Medicinal Chemistry, 2020.
  7. Ferreira-Silva, Margarida; Faria-Silva, Catarina; Carvalheiro, Manuela Colla; Baptista, Pedro; Metselaar, Josbert; Corvo, M. Luisa; Fernandes, Alexandra. "Evaluation of anti-inflammatory effect of quercetin liposomes in hepatic ischemia and reperfusion injury". Paper presented in XIIIth Spanish Portuguese Conference on Controlled Drug Delivery, 2020.
  8. Ferreira-Silva, Margarida; Faria-Silva, Catarina; Carvalheiro, Manuela Colla; Baptista, Pedro; Fernandes, Eduarda; Fernandes, Alexandra; Corvo, M. Luisa. "Evaluation of anti-inflammatory efficacy of liposomal formulations developed for hepatic ischemia and reperfusion injury¿s treatment". Paper presented in 6th International Symposium on Phospholipids in Pharmaceutical Research, 2019.
  9. Ferreira-Silva, Margarida; Faria-Silva, Ana Catarina; Carvalheiro, Manuela Colla; Baptista, Pedro; Josbert Maarten Metselaar; Corvo, M. Luisa; Fernandes, Alexandra. "Assessment Of Anti inflammatory Efficacy Of Liposomal Formulations Developed For The Treatment Of Hepatic Ischemia And Reperfusion Injury". Paper presented in 2019 Controlled Release Society Annual Meeting Exposition, 2019.
  10. Ferreira-Silva, Margarida; Faria-Silva, Catarina; Carvalheiro, Manuela Colla; Baptista, Pedro; Fernandes, Eduarda; Fernandes, Alexandra; Corvo, M. Luisa. "Development of Quercetin Liposomal Formulations for Hepatic Ischemia Reperfusion Injury Prevention". Paper presented in 11th iMed ULisboa Postgraduate Students Meeting & 4th i3DU Meeting, 2019.
  11. Ferreira-Silva, Margarida; Faria-Silva, Ana Catarina; Carvalheiro, Manuela Colla; Baptista, Pedro V.; Fernandes, Eduarda; Fernandes, Alexandra; Corvo, M. Luisa. "Development of Anti-Inflammatory Liposomal Formulations for Hepatic Ischemia/Reperfusion Injury". Paper presented in 10th iMed.ULisboa Postgraduate Students Meeting & 3rd i3DU Meeting, 2018.
  12. Ferreira-Silva, Margarida; Carvalheiro, Manuela Colla; Holovanchuk, Denys; Soares, Helena; H. Susana Marinho; Corvo, M. Luisa. "Antagonist G-labeled long circulating liposomes actively targeted to lung tumor cells". Paper presented in 5th International Symposium on Phospholipids in Pharmaceutical Research;, 2017.
  13. Ferreira-Silva, Margarida; Carvalheiro, Manuela Colla; Holovanchuk, Denys; Soares, Helena; Marinho, H. Susana; Corvo, M. Luisa. "Active targeting of lung tumor cells using antagonist G labeled long circulating liposomes". Paper presented in 8th iMed.ULisboa Postgraduate Students Meeting & 1st i3DU Meeting, 2016.
  14. de Sousa, Andreia D.; Santos, Telma C.; Santos, Filipa C.; Santos, M.S.; Corvo, M. Luisa; Garcia, M. Helena; Tomaz, A. I.; de Almeida, Rodrigo F. M.. "A membrane biophysics approach to the mechanism of action of new active Ruthenium anticancer compounds". Paper presented in CQB-Day 2015, 2015.
  15. Santos, Telma C.; Matos, Cristina P.; Santos, Filipa C.; Corvo, M. Luisa; Garcia, M. Helena; Tomaz, A. I.; de Almeida, Rodrigo F. M.. "Interaction of new active Ruthenium anticancer agentes with lipid bilayers". Paper presented in EBSA 13 - 9th European Biophysics Congress, 2013.
  16. V. Moura; M. Lacerda; P. Figueiredo; M. L. Corvo; M. E. Cruz; M. C. Pedroso de Lima; S. Simoes; J. N. Moreira. "Abstract A129: Targeted delivery of therapeutics to tumor cells and the tumor microenvironment". 2009.
    10.1158/1535-7163.TARG-09-A129
Journal article
  1. Sónia Rocha; Andreia Amaro; Marcos D. Ferreira-Junior; Carina Proença; Artur M. S. Silva; Vera M. Costa; Sara Oliveira; et al. "Melanoxetin: A Hydroxylated Flavonoid Attenuates Oxidative Stress and Modulates Insulin Resistance and Glycation Pathways in an Animal Model of Type 2 Diabetes Mellitus". Pharmaceutics (2024): https://doi.org/10.3390/pharmaceutics16020261.
    10.3390/pharmaceutics16020261
  2. Rocha, Sónia; Beatriz Vicente; Proença, Carina; Vera Silva; Silva, Artur M. S.; Corvo, M. Luisa; Eduarda Fernandes; Freitas, Marisa. "Herbacetin inhibits human fructose 1,6-bisphosphatase and improves insulin resistance in HepG2 cells". (2024):
    Submitted
  3. Rocha, Sónia; AMARO, ANDREIA; Marcos D. Ferreira-Junior; Proença, Carina; Silva, Artur M. S.; Vera M. Costa; Sara Oliveira; et al. "A hydroxylated flavonoid reduces oxidative stress in an animal model of type 2 diabetes mellitus". (2024):
    Submitted
  4. Costa, Clarinda; Casimiro, Teresa; Corvo, M. Luísa; Aguiar-Ricardo, Ana. "Cu, Zn- Superoxide dismutase liposomal dry powder formulations production using supercritical CO2-assisted spray-drying: A proof-of-concept". The Journal of Supercritical Fluids 200 (2023): 105991. http://dx.doi.org/10.1016/j.supflu.2023.105991.
    10.1016/j.supflu.2023.105991
  5. Starosta, Radoslaw; Santos, Telma C.; de Sousa, Andreia F. Dinis F.; Santos, Maria Soledade; Corvo, M. Luisa; Tomaz, Ana Isabel; de Almeida, Rodrigo F. M.. "Assessing the role of membrane lipids in the action of ruthenium(III) anticancer compounds". Frontiers in Molecular Biosciences (2023): https://publons.com/wos-op/publon/55431276/.
    10.3389/FMOLB.2022.1059116
  6. Fernandes, Diana A.; Costa, Eunice; Leandro, Paula; Corvo, M. Luisa. Corresponding author: Corvo, M. Luisa. "Formulation of spray dried enzymes for dry powder inhalers: An integrated methodology". International Journal of Pharmaceutics 615 (2022): 121492. http://dx.doi.org/10.1016/j.ijpharm.2022.121492.
    10.1016/j.ijpharm.2022.121492
  7. Maria Eugénia Meirinhos Cruz; Corvo, M. Luisa; Maria Bárbara Martins; Sandra Simões; Gaspar MM. Corresponding author: Corvo, M. Luisa. "Liposomes as Tools to Improve Therapeutic Enzyme Performance". Pharmaceutics (2022): https://www.mdpi.com/1999-4923/14/3/531.
    Published • 10.3390/pharmaceutics14030531
  8. Rocha, Sónia; Aniceto, Natália; Guedes, Rita C.; Albuquerque, Hélio M. T.; Silva, Vera L. M.; Silva, Artur M. S.; Corvo, M. Luisa; Fernandes, Eduarda; Freitas, Marisa. "An In Silico and an In Vitro Inhibition Analysis of Glycogen Phosphorylase by Flavonoids, Styrylchromones, and Pyrazoles". Nutrients 14 2 (2022): 306. http://dx.doi.org/10.3390/nu14020306.
    10.3390/nu14020306
  9. Ferreira-Silva, Margarida; Faria-Silva, Catarina; Carvalheiro, Manuela C.; Simões, Sandra; Marinho, H. Susana; Marcelino, Paulo; Campos, Maria Celeste; et al. Corresponding author: Corvo, M. Luisa. "Quercetin Liposomal Nanoformulation for Ischemia and Reperfusion Injury Treatment". Pharmaceutics 14 1 (2022): 104. http://dx.doi.org/10.3390/pharmaceutics14010104.
    10.3390/pharmaceutics14010104
  10. Carvalheiro, Manuela; Ferreira-Silva, Margarida; Holovanchuk, Denys; Marinho, H. Susana; Moreira, João Nuno; Soares, Helena; Corvo, M. Luisa; Cruz, Maria Eugénia M.. Corresponding author: Corvo, M. Luisa. "Antagonist G-targeted liposomes for improved delivery of anticancer drugs in small cell lung carcinoma". International Journal of Pharmaceutics 612 (2022): 121380. http://dx.doi.org/10.1016/j.ijpharm.2021.121380.
    10.1016/j.ijpharm.2021.121380
  11. Costa, Clarinda; Nobre, Beatriz; Matos, Ana Sofia; Silva, Ana Sofia; Casimiro, Teresa; Corvo, M. Luisa; Aguiar-Ricardo, Ana. Corresponding author: Corvo, M. Luisa. "Inhalable hydrophilic molecule-loaded liposomal dry powder formulations using supercritical CO2 – assisted spray-drying". Journal of CO2 Utilization 53 (2021): 101709. http://dx.doi.org/10.1016/j.jcou.2021.101709.
    10.1016/j.jcou.2021.101709
  12. Girão, Luciana F. C.; Carvalheiro, Manuela Colla; Ferreira-Silva, Margarida; da Rocha, Surza L. G.; Perales, Jonas; Martins, M. Bárbara F.; Ferrara, Maria Antonieta; Bon, Elba P. S.; Corvo, M. Luisa. Corresponding author: Corvo, M. Luisa. "ASP-Enzymosomes with Saccharomyces cerevisiae Asparaginase II Expressed in Pichia pastoris: Formulation Design and In Vitro Studies of a Potential Antileukemic Drug". International Journal of Molecular Sciences 22 20 (2021): 11120. http://dx.doi.org/10.3390/ijms222011120.
    Published • 10.3390/ijms222011120
  13. Fernandes, Diana A.; Leandro, Paula; Costa, Eunice; Corvo, M. Luisa. Corresponding author: Corvo, M. Luisa. "Dry powder inhaler formulation of Cu,Zn-superoxide dismutase by spray drying: A proof-of-concept". Powder Technology 389 (2021): 131-137. http://dx.doi.org/10.1016/j.powtec.2021.05.008.
    Published • 10.1016/j.powtec.2021.05.008
  14. Noriega-Fernandes, Beatriz; Malmlöf, Maria; Nowenwik, Mattias; Gerde, Per; Corvo, M. Luisa; Costa, Eunice; Malmlof, Maria; Corvo, M. Luisa. Corresponding author: Corvo, M. Luisa. "Dry powder inhaler formulation comparison: Study of the role of particle deposition pattern and dissolution". International Journal of Pharmaceutics 607 (2021): 121025. http://dx.doi.org/10.1016/j.ijpharm.2021.121025.
    10.1016/j.ijpharm.2021.121025
  15. Rocha, Sónia; Lucas, Mariana; Araújo, Alberto N.; Corvo, M. Luisa; Fernandes, Eduarda; Freitas, Marisa. "Optimization and Validation of an In Vitro Standardized Glycogen Phosphorylase Activity Assay". Molecules 26 15 (2021): 4635. http://dx.doi.org/10.3390/molecules26154635.
    10.3390/molecules26154635
  16. Rocha, Sónia; Lucas, Mariana; Ribeiro, Daniela; Corvo, M. Luisa; Fernandes, Eduarda; Freitas, Marisa. "Nano-based drug delivery systems used as vehicles to enhance polyphenols therapeutic effect for diabetes mellitus treatment". Pharmacological Research 169 (2021): 105604. http://dx.doi.org/10.1016/j.phrs.2021.105604.
    10.1016/j.phrs.2021.105604
  17. Rocha, Sónia; Lucas, Mariana; Silva, Vera L.M.; Gomes, Pedro M.O.; Silva, Artur M.S.; Araújo, Alberto N.; Aniceto, Natália; et al. "Pyrazoles as novel protein tyrosine phosphatase 1B (PTP1B) inhibitors: An in vitro and in silico study". International Journal of Biological Macromolecules 181 (2021): 1171-1182. http://dx.doi.org/10.1016/j.ijbiomac.2021.04.061.
    10.1016/j.ijbiomac.2021.04.061
  18. Ferreira-Silva, Margarida; Faria-Silva, Catarina; Viana Baptista, Pedro; Fernandes, Eduarda; Ramos Fernandes, Alexandra; Corvo, M. Luisa; Baptista, Pedro Viana; Fernandes, Alexandra Ramos; Corvo, Maria Luisa. Corresponding author: Corvo, M. Luisa. "Liposomal Nanosystems in Rheumatoid Arthritis". Pharmaceutics 13 4 (2021): 454. http://dx.doi.org/10.3390/pharmaceutics13040454.
    10.3390/pharmaceutics13040454
  19. Ferreira-Silva, Margarida; Faria-Silva, Catarina; Baptista, Pedro Viana; Fernandes, Eduarda; Fernandes, Alexandra Ramos; Corvo, M. Luisa. Corresponding author: Corvo, M. Luisa. "Drug delivery nanosystems targeted to hepatic ischemia and reperfusion injury". Drug Delivery and Translational Research 11 2 (2021): 397-410. http://dx.doi.org/10.1007/s13346-021-00915-8.
    10.1007/s13346-021-00915-8
  20. Costa, Clarinda; Liu, Zehua; Simões, Sandra I.; Correia, Alexandra; Rahikkala, Antti; Seitsonen, Jani; Ruokolainen, Janne; et al. Corresponding author: Corvo, M. Luisa. "One-step microfluidics production of enzyme-loaded liposomes for the treatment of inflammatory diseases". Colloids and Surfaces B: Biointerfaces 199 (2021): 111556. http://dx.doi.org/10.1016/j.colsurfb.2020.111556.
    10.1016/j.colsurfb.2020.111556
  21. De Almeida, Rodrigo F. M.; Marques, Joaquim T.; Silva, Liana C.; Susana Marinho, H.; Corvo, M. L.; Fedeli, Francesca; Faria-Silva, Catarina; Santos, Filipa C.; Bento-Oliveira, Andreia. "Sphingolipid-Enriched Domains in Yeast: Biophysical Properties and Antifungal Interaction". Biophysical Journal (2021): https://publons.com/publon/40843439/.
    10.1016/J.BPJ.2020.11.517
  22. Costa, Clarinda; Casimiro, Teresa; Corvo, Maria Luisa; Aguiar-Ricardo, Ana; Corvo, M. Luisa. "Solid Dosage Forms of Biopharmaceuticals in Drug Delivery Systems Using Sustainable Strategies". Molecules 26 24 (2021): 7653. https://publons.com/publon/50482086/.
    10.3390/MOLECULES26247653
  23. Costa, Clarinda; Liu, Zehua; Martins, João P.; Correia, Alexandra; Figueiredo, Patrícia; Rahikkala, Antti; Li, Wei; et al. Corresponding author: Santos, Hélder A.. "All-in-one microfluidic assembly of insulin-loaded pH-responsive nano-in-microparticles for oral insulin delivery". Biomaterials Science 8 12 (2020): 3270-3277. http://dx.doi.org/10.1039/d0bm00743a.
    10.1039/d0bm00743a
  24. Noriega, Beatriz; Malmlof, Maria; Nowenwik, Mattias; Gerde, Per; Corvo, M. Luisa; Costa, Eunice. "BIORELEVANT DISSOLUTION TO DIFFERENTIATE FORMULATION PERFORMANCE FOR INHALATION". Journal of Aerosol Medicine and Pulmonary Drug Delivery (2020): https://publons.com/publon/33874227/.
  25. Pedrosa, Pedro; Corvo, M. Luisa; Ferreira-Silva, Margarida; Martins, Pedro; Carvalheiro, Manuela Colla; Costa, Pedro M.; Martins, Carla; et al. "Targeting Cancer Resistance via Multifunctional Gold Nanoparticles". International Journal of Molecular Sciences 20 21 (2019): 5510. http://dx.doi.org/10.3390/ijms20215510.
    10.3390/ijms20215510
  26. Fernandes, Diana A.; Pereira, Joao; Leandro, Paula; Corvo, M. Luisa; Costa, Eunice. "HOW TO SUCCESSFULLY SPRAY DRY BIOPHARMACEUTICALS TARGETING THE LUNGS: A NOVEL INTEGRATED METHODOLOGY". Journal of Aerosol Medicine and Pulmonary Drug Delivery (2019): https://publons.com/publon/29343397/.
  27. Silva, Mariana F.; Fernandes, Diana A.; Braga, Maria; Eloy, Antonio; Marques, Joao; Corvo, M. Luisa; Costa, Eunice. "NASAL DRY POWDER DELIVERY: IMPLEMENTING A FORMULATION INDEPENDENT SPRAY DRYING PROCESS". Journal of Aerosol Medicine and Pulmonary Drug Delivery (2019): https://publons.com/publon/29617389/.
  28. Simoes, Sandra; Lopes, Rui; Dias Campos, Maria Celeste; Marruz, Maria Joao; Meirinhos da Cruz, Maria Eugenia; Corvo, Luisa. "Animal models of acute gastric mucosal injury: Macroscopic and microscopic evaluation". Animal Models and Experimental Medicine (2019): https://publons.com/wos-op/publon/14138388/.
    10.1002/AME2.12060
  29. Marinho, H. Susana; Marcelino, Paulo; Soares, Helena; Corvo, M. Luisa. Corresponding author: Corvo, M. Luisa. "Gene Silencing using siRNA for Preventing Liver Ischaemia-Reperfusion Injury". Current Pharmaceutical Design 24 23 (2018): 2692-2700. http://dx.doi.org/10.2174/1381612824666180807124356.
    10.2174/1381612824666180807124356
  30. Corvo, M. Luisa. "ULTRASONIC VERSUS TWO-FLUID NOZZLE IN A SPRAY DRYING PROCESS: A COMPARATIVE STUDY FOR THE PRODUCTION OF DRY POWDER INHALER FORMULATIONS FOR BIOPHARMACEUTICAL DELIVERY". Journal of Aerosol Medicine and Pulmonary Drug Delivery (2018): https://publons.com/publon/19352746/.
  31. Corvo, M. Luisa. "DISSOLUTION OF ORALLY INHALED DRUGS USING DISSOLVIT (R): INFLUENCE OF A NEWLY DESIGNED PRE-SEPARATOR FOR PARTICLE COLLECTION". Journal of Aerosol Medicine and Pulmonary Drug Delivery (2018): https://publons.com/publon/19352745/.
  32. Marcelino, Paulo; Marinho, H. Susana; Campos, Maria Celeste; Neves, Ana Rita; Real, Carla; Fontes, Filipa S.; Carvalho, Alexandra; et al. Corresponding author: Corvo, M. Luisa. "Therapeutic activity of superoxide dismutase-containing enzymosomes on rat liver ischaemia-reperfusion injury followed by magnetic resonance microscopy". European Journal of Pharmaceutical Sciences 109 (2017): 464-471. http://dx.doi.org/10.1016/j.ejps.2017.09.008.
    10.1016/j.ejps.2017.09.008
  33. Jarak, Ivana; Carrola, Joana; Barros, António S.; Gil, Ana M.; Pereira, Maria de Lourdes; Corvo, M. Luisa; Duarte, Iola F.. "From the Cover: Metabolism Modulation in Different Organs by Silver Nanoparticles: An NMR Metabolomics Study of a Mouse Model". Toxicological Sciences 159 2 (2017): 422-435. http://dx.doi.org/10.1093/toxsci/kfx142.
    10.1093/toxsci/kfx142
  34. Carvalho, Alexandra; Gonçalves, M Clara; Corvo, M. Luisa; Martins, M Bárbara F. "Development of New Contrast Agents for Imaging Function and Metabolism by Magnetic Resonance Imaging". Magnetic Resonance Insights 10 (2017): 1178623X1772213. http://dx.doi.org/10.1177/1178623x17722134.
    10.1177/1178623x17722134
  35. Fernandes, Alexandra R.; Jesus, João; Martins, Pedro; Figueiredo, Sara; Rosa, Daniela; Martins, Luísa M.R.D.R.S.; Corvo, M. Luisa; et al. "Multifunctional gold-nanoparticles: A nanovectorization tool for the targeted delivery of novel chemotherapeutic agents". Journal of Controlled Release 245 (2017): 52-61. http://dx.doi.org/10.1016/j.jconrel.2016.11.021.
    10.1016/j.jconrel.2016.11.021
  36. Corvo, M. Luisa. "PADDLE OVER DISK AS A DISSOLUTION TEST FOR ORALLY INHALED DRUGS: DISCRIMINATING COMPOSITE FROM CARRIER-BASED FORMULATIONS". Journal of Aerosol Medicine and Pulmonary Drug Delivery (2017): https://publons.com/publon/8264584/.
  37. MC, Gonçalves; AM, Rodrigues; A, Sabino; Corvo, M. Luisa; MB, Martins. "Liposil Nanocarriers for Pharmaceutical Applications: Synthesis Innovations". Journal of Nanomedicine & Nanotechnology 08 04 (2017): http://dx.doi.org/10.4172/2157-7439.1000450.
    10.4172/2157-7439.1000450
  38. Corvo, M. Luisa. "IMPACT OF SPRAY DRYING ON SUPEROXIDE DISMUTASE ACTIVITY IN COMPOSITE SYSTEMS WITH OPTIMAL AERODYNAMIC PERFORMANCE FOR DRY POWDER INHALERS". Journal of Aerosol Medicine and Pulmonary Drug Delivery (2017): https://publons.com/publon/8264604/.
  39. Tomaz, Ana Isabel; de Sousa, Andreia D.; Santos, Telma C.; Soledade Santos, M.; Corvo, M. Luisa; Matos, Cristina; Helena Garcia, M.; de Almeida, Rodrigo F. M.. "On the mechanism of action of new active ruthenium anticancer compounds: a model membrane biophysics approach". Journal of Biological Inorganic Chemistry (2017): https://publons.com/publon/8264586/.
  40. Raposo, L. R.; Roma-Rodrigues, C.; Faisca, P.; Alves, M.; Henriques, J.; Carvalheiro, M. C.; Corvo, M. Luisa; et al. "Immortalization and characterization of a new canine mammary tumour cell line FR37-CMT". Veterinary and Comparative Oncology 15 3 (2017): 952-967. https://publons.com/publon/4005012/.
    10.1111/VCO.12235
  41. "CURRENT ASPECTS OF BREAST CANCER THERAPY AND DIAGNOSIS BASED ON A NANOCARRIER APPROACH". Nanostructures for Cancer Therapy (2017): https://publons.com/publon/15103124/.
    10.1016/B978-0-323-46144-3.00027-1
  42. Duarte, Íris; Corvo, M. Luisa; Serôdio, Pedro; Vicente, João; Pinto, João F.; Temtem, Márcio. "Production of nano-solid dispersions using a novel solvent-controlled precipitation process — Benchmarking their in vivo performance with an amorphous micro-sized solid dispersion produced by spray drying". European Journal of Pharmaceutical Sciences 93 (2016): 203-214. http://dx.doi.org/10.1016/j.ejps.2016.08.011.
    10.1016/j.ejps.2016.08.011
  43. Marçal, R.; Carrola, J.; Jarak, I.; Corvo, M. Luisa; Duarte, I.F.; De Lourdes Pereira, M.. "Microscopic studies of liver and kidney in mice exposed to silver nanoparticles". Microscopy and Microanalysis 22 (2016): 18-19. http://www.scopus.com/inward/record.url?eid=2-s2.0-85014579842&partnerID=MN8TOARS.
    10.1017/S1431927616000283
  44. Corvo, M. Luisa; Mendo, Ana Soraia; Figueiredo, Sara; Gaspar, Rogerio; Larguinho, Miguel; Guedes da Silva, M. Fatima C.; Baptista, Pedro Viana; et al. "Liposomes as Delivery System of a Sn(IV) Complex for Cancer Therapy". Pharmaceutical Research 33 6 (2016): 1351-1358. https://publons.com/publon/4004971/.
    10.1007/S11095-016-1876-6
  45. Corvo, M.L.; Marinho, H.S.; Marcelino, P.; Lopes, R.M.; Vale, C.A.; Marques, C.R.; Martins, L.C.D.; et al. "Superoxide dismutase enzymosomes: Carrier capacity optimization, in vivo behaviour and therapeutic activity". Pharmaceutical Research 32 1 (2015): 91-102. http://www.scopus.com/inward/record.url?eid=2-s2.0-84939630914&partnerID=MN8TOARS.
    10.1007/s11095-014-1447-7
  46. Corvo, M. Luisa; Marinho, H. Susana; Marcelino, Paulo; Lopes, Rui M.; Vale, Carlos A.; Marques, Claúdia R.; Martins, Luísa C.D.; et al. Corresponding author: Corvo, M. Luisa. "Superoxide Dismutase Enzymosomes: Carrier Capacity Optimization, in Vivo Behaviour and Therapeutic Activity". Pharmaceutical Research 32 1 (2014): 91-102. http://dx.doi.org/10.1007/s11095-014-1447-7.
    10.1007/s11095-014-1447-7
  47. A. Carvalho; M.B.F. Martins; Corvo, M. Luisa; G. Feio; Carvalho, A.; Martins, M.B.F.; Corvo, M.L.; Feio, G.. "Enhanced contrast efficiency in MRI by PEGylated magnetoliposomes loaded with PEGylated SPION: Effect of SPION coating and micro-environment". Materials Science and Engineering: C 43 (2014): 521-526. https://publons.com/publon/8264605/.
    10.1016/J.MSEC.2014.07.055
  48. A.M. Antunes; C. Teixeira; M.L. Corvo; R. Perdigoto; E. Barroso; P. Marcelino. "Prophylactic Use of Liposomal Amphotericin B in Preventing Fungal Infections Early After Liver Transplantation: A Retrospective, Single-Center Study". Transplantation Proceedings (2014): https://publons.com/publon/8264606/.
    10.1016/J.TRANSPROCEED.2014.06.065
  49. Martins, M.B.A.F.; Corvo, M. Luisa; Marcelino, P.; Marinho, H.S.; Feio, G.; Carvalho, A.; M. Bárbara A.F. Martins; et al. "New long circulating magnetoliposomes as contrast agents for detection of ischemia-reperfusion injuries by MRI". Nanomedicine: Nanotechnology, Biology, and Medicine 10 1 (2014): 207-214. http://www.scopus.com/inward/record.url?eid=2-s2.0-84891009416&partnerID=MN8TOARS.
    10.1016/j.nano.2013.06.008
  50. Antunes, A.M.; Teixeira, C.; Corvo, M. Luisa; Perdigoto, R.; Barroso, E.; Marcelino, P.. "Prophylactic use of liposomal amphotericin B in preventing fungal infections early after liver transplantation: A retrospective, single-center study". Transplantation Proceedings 46 10 (2014): 3554-3559. http://www.scopus.com/inward/record.url?eid=2-s2.0-84926393321&partnerID=MN8TOARS.
    10.1016/j.transproceed.2014.06.065
  51. Cristina de Mello-Sampayo; Corvo, M. Luisa; Rogério Mendes; Diana Duarte; Joana Lucas; Rui Pinto; Ana Paula Batista; et al. "Insights on the safety of carotenogenic Chlorella vulgaris in rodents". Algal Research 2 4 (2013): 409-415. https://publons.com/publon/7241984/.
    10.1016/J.ALGAL.2013.07.005
  52. L. Figueiredo; A. Cadete; L.M.D. Gonçalves; Corvo, M. Luisa; A.J. Almeida; Figueiredo, L.; Cadete, A.; et al. "Intranasal immunisation of mice against Streptococcus equi using positively charged nanoparticulate carrier systems". Vaccine 30 46 (2012): 6551-6558. https://publons.com/publon/7785574/.
    10.1016/J.VACCINE.2012.08.050
  53. Moura, Vera; Lacerda, Manuela; Figueiredo, Paulo; Corvo, Maria L.; Cruz, Maria E. M.; Soares, Raquel; Pedroso de Lima, Maria C.; et al. "Targeted and intracellular triggered delivery of therapeutics to cancer cells and the tumor microenvironment: impact on the treatment of breast cancer". Breast Cancer Research and Treatment 133 1 (2012): 61-73. https://publons.com/publon/6041030/.
    10.1007/S10549-011-1688-7
  54. Lopes, R.M.; Corvo, M. Luisa; Eleutério, C.V.; Carvalheiro, M.C.; Scoulica, E.; Cruz, M.E.M.; Rui M. Lopes; et al. "Formulation of oryzalin (ORZ) liposomes: In vitro studies and in vivo fate". European Journal of Pharmaceutics and Biopharmaceutics 82 2 (2012): 281-290. http://www.scopus.com/inward/record.url?eid=2-s2.0-84867877363&partnerID=MN8TOARS.
    10.1016/j.ejpb.2012.06.013
  55. Gomes, A.; Fernandes, E.; Lima, J.L.F.C.; Mira, L.; Corvo, M. Luisa. "Molecular mechanisms of anti-inflammatory activity mediated by flavonoids". Current Medicinal Chemistry 15 16 (2008): 1586-1605. http://www.scopus.com/inward/record.url?eid=2-s2.0-48249112172&partnerID=MN8TOARS.
    10.2174/092986708784911579
  56. Maria Manuela Gaspar; Otto C. Boerman; Peter Laverman; Corvo, M. Luisa; Gert Storm; Maria Eugénia Meirinhos Cruz; Gaspar, M.M.; et al. Corresponding author: Corvo, M. Luisa. "Enzymosomes with surface-exposed superoxide dismutase: In vivo behaviour and therapeutic activity in a model of adjuvant arthritis". Journal of Controlled Release 117 2 (2007): 186-195. https://publons.com/publon/7241489/.
    10.1016/J.JCONREL.2006.10.018
  57. Simões, S.I.; Delgado, T.C.; Lopes, R.M.; Jesus, S.; Ferreira, A.A.; Morais, J.A.; Cruz, M.E.M.; et al. "Developments in the rat adjuvant arthritis model and its use in therapeutic evaluation of novel non-invasive treatment by SOD in Transfersomes". Journal of Controlled Release 103 2 (2005): 419-434. http://www.scopus.com/inward/record.url?eid=2-s2.0-14844292727&partnerID=MN8TOARS.
    10.1016/j.jconrel.2004.12.008
  58. Cruz, M.E.M.; Gaspar, M.M.; Martins, M.B.F.; Corvo, M. Luisa. "Liposomal superoxide dismutases and their use in the treatment of experimental arthritis". Nutrients 391 (2005): http://www.scopus.com/inward/record.url?eid=2-s2.0-13844294423&partnerID=MN8TOARS.
    10.1016/S0076-6879(05)91022-7
  59. Simões, S.I.D.; Eleutério, C.V.; Cruz, M.E.M.; Corvo, M. Luisa; Martins, M.B.F.. "Biochemical changes in arthritic rats: Dehydroascorbic and ascorbic acid levels". European Journal of Pharmaceutical Sciences 18 2 (2003): 185-189. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037317115&partnerID=MN8TOARS.
    10.1016/S0928-0987(02)00258-0
  60. Gaspar, M.M.; Martins, M.B.; Corvo, M. Luisa; Cruz, M.E.M.. "Design and characterization of enzymosomes with surface-exposed superoxide dismutase". Biochimica et Biophysica Acta - Biomembranes 1609 2 (2003): 211-217. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037474030&partnerID=MN8TOARS.
    10.1016/S0005-2736(02)00702-2
  61. Corvo, M. Luisa; Jorge, J.C.S; Van't Hof, R.; Cruz, M.Eugénia M.; Crommelin, D.J.A; Storm, G.. Corresponding author: Corvo, M. Luisa. "Superoxide dismutase entrapped in long-circulating liposomes: Formulation design and therapeutic activity in rat adjuvant arthritis". Biochimica et Biophysica Acta - Biomembranes 1564 1 (2002): 227-236. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037136060&partnerID=MN8TOARS.
    10.1016/S0005-2736(02)00457-1
  62. Corvo, M. Luisa; Boerman, O.C.; Oyen, W.J.G.; Jorge, J.C.S.; Cruz, M.E.M.; Crommelin, D.J.A.; Storm, G.. Corresponding author: Corvo, M. Luisa. "Subcutaneous administration of superoxide dismutase entrapped in long circulating liposomes: In vivo fate and therapeutic activity in an inflammation model". Pharmaceutical Research 17 5 (2000): 600-606. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034122582&partnerID=MN8TOARS.
    10.1023/A:1007577101964
  63. Corvo, M. Luisa; Boerman, O.C.; Oyen, W.J.G.; Van Bloois, L.; Cruz, M.E.M.; Crommelin, D.J.A.; Storm, G.. Corresponding author: Corvo, M. Luisa. "Intravenous administration of superoxide dismutase entrapped in long circulating liposomesII. In vivo fate in a rat model of adjuvant arthritis". Biochimica et Biophysica Acta - Biomembranes 1419 2 (1999): 325-334. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033038007&partnerID=MN8TOARS.
    10.1016/S0005-2736(99)00081-4
  64. Corvo, M. Luisa; Martins, M.B.; Francisco, A.P.; Morais, J.G.; Cruz, M.E.M.. Corresponding author: Corvo, M. Luisa. "Liposomal formulations of Cu,Zn-superoxide dismutase: Physicochemical characterization and activity assessment in an inflammation model". Journal of Controlled Release 43 1 (1997): 1-8. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031060394&partnerID=MN8TOARS.
    10.1016/S0168-3659(96)01473-3
  65. Boerman, O.C.; Oyen, W.J.G.; Storm, G.; Corvo, M. Luisa; Van Bloois, L.; Van Der Meer, J.W.M.; Corstens, F.H.M.; et al. "Technetium-99m labelled liposomes to image experimental arthritis". Annals of the Rheumatic Diseases 56 6 (1997): 369-373. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030741253&partnerID=MN8TOARS.
    10.1136/ard.56.6.369
  66. Cruz, M.E.M.; Corvo, M. Luisa; Esteves, A.M.; Lopes, F.C.; Soler, R.P.. "Enzymatic liposomal formulations". European Journal of Pharmacology 183 2 (1990): 399-400. http://www.scopus.com/inward/record.url?eid=2-s2.0-0025329294&partnerID=MN8TOARS.
    10.1016/0014-2999(90)93280-4
Newspaper article
  1. Vale de Almeida, M. ; Advirta, Isabel; Corvo, Maria Luisa ; Lima, Margarida Rêgo; Côrte-Real, Paulo. "Filho da Mãe", Público, 2018
Thesis / Dissertation
  1. Francisco, Mafalda Vaz. "Phenylalanine hydroxylase (pah) enzymosomes : development of a nanosystem for enzyme substitution/replacement therapies". Master, 2023. http://hdl.handle.net/10362/152664.
  2. Sequeira, Clarinda Isabel da Silva e Costa. "Integrated manufacture of Liposomal dry powder formulations". PhD, 2023. http://hdl.handle.net/10362/152089.
  3. Pereira, Tatiana Filipa Rebelo. "Formulações lipossomais de glucocorticóides para o tratamento da Artrite Reumatóide: preparação, caracterização e avaliação in vitro". Master, 2023. http://hdl.handle.net/10451/64269.
  4. Casaca, Ana Sofia Brito. "Development of quercetin-loaded liposomal dry powder formulations for the treatment of inflammatory lung diseases". PhD, 2022. http://hdl.handle.net/10362/133064.
  5. Soares, Joana Baranito Pereira. "Mechanical stability testing of spray freeze-dried particles". Master, 2022. http://hdl.handle.net/10451/58154.
  6. Noriega-Fernandes, Beatriz. "Dissolution of Dry Powder Inhaler formulations : in vitro / in vivo correlations". PhD, 2022. http://hdl.handle.net/10451/54920.
  7. Santos, Luís Filipe Pereira dos. "Development of Liposomal Formulations for Treatment of Hepatic Ischemia and Reperfusion Injury". Master, 2022. http://hdl.handle.net/10451/55510.
  8. "Biopharmaceuticals Formulations for Dry Powder Inhalers". PhD, Universidade de Lisboa Faculdade de Farmácia, 2021.
  9. Fernandes, Jessica Alexandra Silva. "Aquaporins involvement in hepatic ischemia reperfusion injury". Master, 2021. http://hdl.handle.net/10451/54121.
  10. Fernandes, Diana. "Biopharmaceutical formulations for dry powder inhalers". PhD, 2021. http://hdl.handle.net/10451/54686.
  11. "Development of Phenylalanine Hydroxylase Enzymosomes for the Treatment of Phenylketonuria". Master, Universidade de Lisboa Faculdade de Farmácia, 2020.
  12. "Aquaporins involvement in hepatic ischemia reperfusion injury". Master, Universidade de Lisboa Faculdade de Farmácia, 2020.
  13. "DTPA And Antibiotic DPI Formulations to Treat Pulmonary Biofilm Infections". Master, Universidade de Lisboa Faculdade de Farmácia, 2020.
  14. Grosso, Filipa Isabel Micaelo. "DTPA and antibiotic DPI formulations to treat pulmonary biofilm infections". Master, 2020. http://hdl.handle.net/10451/54774.
  15. Laia, Carolina Farate e. "Nanopartículas superparamagnéticas de óxido de ferro (SPION): potencialidade da sua aplicação como transportador de genes e agente de contraste". Master, 2020. http://hdl.handle.net/10451/52516.
  16. Silva, Mariana Fernandes da. "Advanced particle engineering and characterization of model biopharmaceuticals for dry powder inhaler formulations". Master, Universidade de Lisboa Faculdade de Farmácia, 2018. http://hdl.handle.net/10451/40064.
  17. Silva, Ana Margarida Ferreira da. "Estudo do direcionamento ativo de nanossistemas lipídicos com antagonista G para células de cancro de pulmão". Master, Universidade de Lisboa Faculdade de Farmácia, 2016. http://hdl.handle.net/10451/25138.
  18. Galhardo, Guilherme Manuel Gonçalves. "Estudo da conjugação de lipossomas de longo tempo de circulação com ácido fólico para direcionamento para os recetores de folato". Master, Universidade de Lisboa Faculdade de Farmácia, 2016. http://hdl.handle.net/10451/34574.
  19. Conim, Andreia Luís da Silva Ferreira; Garrido, Madalena Frias do Vale. "Avaliação in vivo da capacidade anti-inflamatória e antioxidante do farelo de arroz como aditivo alimentar". Master, Universidade de Lisboa Instituto Superior de Agronomia, 2015. http://hdl.handle.net/10451/26961.
  20. Holovanchuk, Denys. "Otimização do direcionamento para células tumorais de nanosistemas lipídicos para uso terapêutico". Master, 2014. http://hdl.handle.net/10451/12376.
  21. "Desenvolvimento e caracterização de nanoestruturas de liposil como sistema de transporte de fármacos". Master, Universidade de Lisboa Instituto Superior Técnico, 2013.
  22. Fontes, Filipa Sobreira Pires Salavessa. "Efeito da administração de enzimossomas de superóxido dismutase na lesão de reperfusão do fígado: estudos num modelo animal de isquémia/reperfusão". Master, Universidade de Lisboa Faculdade de Ciências, 2012. http://hdl.handle.net/10451/8837.
  23. Figueiredo, Lara Isabel Martins. "Avaliação da integridade e da actividade de antigénios de Streptococcus Equi encapsulados em lipossomas". Master, 2010. http://hdl.handle.net/10451/5628.
  24. Corvo, M. Luisa. "Liposomes for the targeted delivery of superoxide dismutase to arthritic sites". PhD, Universiteit Utrecht, 1998. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031820187&partnerID=MN8TOARS.
Activities

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2022/03 - Current Screening of CDK4/6 and PI3K inhibitors for metastatic breast cancer treatment
Co-supervisor of Ana Cristina Martins de Figueiredo
Biochemistry and Human Biology (PhD)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2018/03 - Current Integrated Manufacture of Liposomal Dry Powder Formulations PD/BD/142880/2018
Co-supervisor of Clarinda Isabel da Silva e Costa
Química Verde e Sustentabilidade (PhD)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2018/01 - Current Targeting liver ischemia reperfusion injury: nanoformulations for gene silencing PD/BD/135264/2017, I3DU
Supervisor of Ana Margarida Ferreira da Silva
 PhD (PhD)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2023 - 2023 Formulation and Device combo for nose to brain drug delivery
Supervisor
 Engenharia Farmacêutica (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2019 - 2023 Flavonoids loaded in nanocarriers as an approach to increase their bioefficacy against Diabetes mellitus PD/BD/145169/2019
Co-supervisor of Sónia Aguiar da Rocha
 Medicamento e Inovação Farmacêutica (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2020 - 2020 DTPA and Antibiotic DPI formulations to treat pulmonary biofilm infections
Supervisor
 Engenharia Farmacêutica (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2020 - 2020 Targeting liver ischemia and reperfusion injury: nanoformulations for advanced drug/gene delivery
Supervisor
 Farmácia (PhD)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2020 - 2020 Integrated Manufacture Of Liposomal Dry Powder Formulations
Co-supervisor
 Química Sustentável (associação) (PhD)
Universidade NOVA de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2018 - 2018 Advanced particle engineering and characterization of model biopharmaceuticals for dry powder inhaler formulations
Supervisor
 Engenharia Farmacêutica (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2017 - 2017 Dissolution of Dry Powder Inhaler formulations: in vitro/in vivo correlations
Supervisor
 Farmácia (PhD)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2017 - 2017 Biopharmaceuticals Formulations for Dry Powder Inhalers
Supervisor
 Farmácia (PhD)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2015 - 2015 Avaliação in vivo do potencial de redução de colesterol, da capacidade antioxidante e anti-inflamatória do farelo de arroz
Supervisor
 Engenharia Alimentar (Master)
Universidade de Lisboa Instituto Superior de Agronomia, Portugal
2014 - 2014 Otimização do direcionamento para células tumorais de nanosistemas lipídicos para uso terapêutico
Supervisor
 Bioquímica (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2015 Multifunctional nano-in-micro formulations for lung cancer theragnosis
(Thesis) Main arguer
 Ana Sofia Matias da Silva (PhD)
Universidade Nova de Lisboa, Portugal

Conference scientific committee

Conference name Conference host
2021/12/01 - 2022/02/28 XIV Spanish-Portuguese Conference on Controlled Drug Delivery. Designing the way to the peak University of La Laguna - Virtual meeting
2020/01/22 - 2020/01/24 XIIIth Spanish-Portuguese Conference on Controlled Drug Delivery 25th ANNIVERSARY
2018/01/14 - 2018/01/14 Tailoring drug delivery systems to the patients’ needs XII Spanish-Portuguese Conference on Controlled Drug Delivery
Distinctions

Award

2019 X Prêmio 2019 Octávio Frias de Oliveira
Universidade de São Paulo Instituto do Câncer do Estado de São Paulo, Brazil

Other distinction

1998 Graduate student/young scientist award
CRS-The Nagai Foundation Graduate Student Award, Las Vegas, U.S.A, United States
1998 young scientist award
CRS-Becton Dixkinson award, United States