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Anna Szóstek-Mioduchowska. Completed the Doktor (PhD) in doctoral course in 2012 by Uniwersytet Medyczny w Bialymstoku and Magister in master course in 2008 by Uniwersytet Warminsko-Mazurski. Is Researcher in Instytut Rozrodu Zwierzat I Badan Zywnosci PAN. Published 59 articles in journals. Has 1 book(s). Supervised 3 PhD thesis(es). Has received 7 awards and/or honors. Participates and/or participated as Master Student Fellow in 1 project(s), PhD Student Fellow in 1 project(s), Principal investigator in 5 project(s), Research Technician Fellow in 2 project(s) and Researcher in 2 project(s). Works in the area(s) of Agrarian Sciences with emphasis on Veterinary Sciences. In his curriculum Ciência Vitae the most frequent terms in the context of scientific, technological and artistic-cultural output are: uterus; mare; fibrosis; immune system; extracellular matrix; .
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Identification

Personal identification

Full name
Anna Szóstek-Mioduchowska

Citation names

  • Szóstek-Mioduchowska, Anna

Author identifiers

Ciência ID
8516-DDA2-7955
ORCID iD
0000-0003-4204-1698

Email addresses

  • a.szostek-mioduchowska@pan.olsztyn.pl (Professional)

Knowledge fields

  • Agrarian Sciences - Veterinary Sciences

Languages

Language Speaking Reading Writing Listening Peer-review
English Intermediate (B1) Intermediate (B1) Intermediate (B1) Intermediate (B1)
German Intermediate (B1) Intermediate (B1) Intermediate (B1) Intermediate (B1)
Education
Degree Classification
2012
Concluded
 doctoral course (Doktor (PhD))
Uniwersytet Medyczny w Bialymstoku, Poland
"Expression of prostaglandin synthases and cytokines and their receptors in the equine endometrium during the estrous cycle in the course of fibrosis" (THESIS/DISSERTATION)
 5
2008
Concluded
 master course (Magister)
Uniwersytet Warminsko-Mazurski, Poland
"Does tumor necrosis factor - a modulates sensitivity of bovine corpus luteum to selected luteotropic factors?" (THESIS/DISSERTATION)
 5
Affiliation

Science

Category
Host institution 		Employer
2013/10/01 - Current Researcher (Research) Instytut Rozrodu Zwierzat I Badan Zywnosci PAN, Poland
2014/12/01 - 2015/11/30 Postdoc (Research) Okayama Daigaku Daigakuin Shizen Kagaku Kenkyuka Seimei Iyo Kogaku Senko, Japan

Others

Category
Host institution 		Employer
2012/10/01 - 2013/09/30 Postdoctoral Research Fellow working on “Endometrial fibrosis as a potential reason for the implantation disorders and early pregnancy loss in mares: role of sex steroids, prostaglandins, lisophosphat Instytut Rozrodu Zwierzat I Badan Zywnosci PAN, Poland
Projects

Grant

Designation Funders
2021/09/01 - 2025/08/31 The understanding of molecular mechanisms of interactions between macrophages and endometrial fibroblasts in processes related to pathogenesis of endometrosis in mares
2020/37/B/NZ9/03355
Principal investigator
2020/09/01 - 2024/08/30 The interaction of T helper cells subsets with endometrial fibroblasts in processes associated to development of mare endometrosis
2019/35/D/NZ9/02989
Principal investigator
2017/12/23 - 2018/12/22 Endometrial miRNA analysis in equine endometrosis/ Analiza miRNA w blonie sluzowej macicy w endometrosis u klaczy
2017/01/X/NZ5/01528
Principal investigator
2015/03/15 - 2018/12/05 The role of myofibroblastów in chronic degenerative endometritis in mare
0463/IP1/2015/73
Principal investigator
2016/01/08 - 2017/01/08 The role of TGF-ß1 in the pathogenesis of endometrosis
UMO-KNOW2016/IRZiBZ/ESR2/01/4
Principal investigator
2012 - 2017 Endometrial fibrosis as a potential for the implantation disorders and early pregnancy loss in mares: participation of sex steroids, prostaglandins and lysophosphatidic acid and their receptors in pathogenesis
011/02/A/NZ5/00338
Researcher
2011 - 2014 The role of tumor necrosis factor-a (TNF-a) in pathogenesis of lipopolysaccharide (LPS) -induced endometrial-pyometer syndrome in cats under in vitro conditions
N N 308 560740
Researcher
2011 - 2013 Does feline placenta contribute to maintaining hormonal homeostasis during pregnancy?”;
IP2011 048971
Research Technician Fellow
2010 - 2012 The effect of ovarian steroids and selected pro-inflammatory cytokines on production and secretion of prostaglandins in mare's uterus: in vitro study
DPN N5/COST/2010
PhD Student Fellow
2010 - 2012 Luteotropic mechanisms in cats during the sexual cycle and pregnancy
IP2010 037570
Research Technician Fellow
2007 - 2010 Participation of glucocorticosteroids in the mechanism of fetal signaling action - interferon-t: modulating effect on synthesis and secretion of prostaglandins in uterus in cow
N308 3279 33
Master Student Fellow
Outputs

Publications

Book
  1. Szóstek-Mioduchowska, Anna. Phytoestrogen coumestrol and its metabolite in mares' plasma after clover mixed pasture and alfalfa pellets ingestion. 2012.
    10.3920/978-90-8686-755-4_3
Journal article
  1. Sadowska, Agnieszka; Molcan, Tomasz; Wójtowicz, Anna; Lukasik, Karolina; Pawlina-Tyszko, Klaudia; Gurgul, Artur; Ferreira-Dias, Graca; Skarzynski, Dariusz J.; Szóstek-Mioduchowska, Anna. "Bioinformatic analysis of endometrial miRNA expression profile at day 26–28 of pregnancy in the mare". Scientific Reports 14 1 (2024): http://dx.doi.org/10.1038/s41598-024-53499-x.
    10.1038/s41598-024-53499-x
  2. Piotrowska-Tomala, Katarzyna Karolina; Jonczyk, Agnieszka Walentyna; Szóstek-Mioduchowska, Anna; Hojo, Takuo; Zebrowska, Ewelina; Katila, Terttu; Ferreira-Dias, Graca; Skarzynski, Dariusz Jan. "Intrauterine devices influence prostaglandin secretion by equine uterus: in vitro and in vivo studies". BMC Veterinary Research 20 1 (2024): http://dx.doi.org/10.1186/s12917-024-03889-0.
    10.1186/s12917-024-03889-0
  3. Szóstek-Mioduchowska, A.; Wójtowicz, A.; Sadowska, A.; Moza Jalali, B.; Slyszewska, M.; Lukasik, K.; Gurgul, A.; et al. "Transcriptomic profiling of mare endometrium at different stages of endometrosis". Scientific Reports 13 1 (2023): http://dx.doi.org/10.1038/s41598-023-43359-5.
    10.1038/s41598-023-43359-5
  4. Wójtowicz, Anna; Molcan, Tomasz; Lukasik, Karolina; Zebrowska, Ewelina; Pawlina-Tyszko, Klaudia; Gurgul, Artur; Szmatola, Tomasz; et al. "The potential role of miRNAs and regulation of their expression in the development of mare endometrial fibrosis". Scientific Reports 13 1 (2023): http://dx.doi.org/10.1038/s41598-023-42149-3.
    10.1038/s41598-023-42149-3
  5. Amaral, Ana; Cebola, Nélio; Szóstek-Mioduchowska, Anna; Rebordão, Maria Rosa; Kordowitzki, Pawel; Skarzynski, Dariusz; Ferreira-Dias, Graça. "Inhibition of Myeloperoxidase Pro-Fibrotic Effect by Noscapine in Equine Endometrium". International Journal of Molecular Sciences 24 4 (2023): 3593. http://dx.doi.org/10.3390/ijms24043593.
    10.3390/ijms24043593
  6. Alpoim-Moreira, Joana; Fernandes, Carina; Pimenta, Jorge; Bliebernicht, Miguel; Rebordão, Maria Rosa; Castelo-Branco, Pedro; Szóstek-Mioduchowska, Anna; Skarzynski, Dariusz J.; Ferreira-Dias, Graça. "Metallopeptidades 2 and 9 genes epigenetically modulate equine endometrial fibrosis". Frontiers in Veterinary Science 9 (2022): http://dx.doi.org/10.3389/fvets.2022.970003.
    Published • 10.3389/fvets.2022.970003
  7. Alpoim-Moreira, Joana; Fernandes, Carina; Rebordão, Maria Rosa; Costa, Ana Luísa; Bliebernicht, Miguel; Nunes, Telmo; Szóstek-Mioduchowska, Anna; Skarzynski, Dariusz J.; Ferreira-Dias, Graça. "Collagen Type III as a Possible Blood Biomarker of Fibrosis in Equine Endometrium". Animals 12 14 (2022): 1854. http://dx.doi.org/10.3390/ani12141854.
    Published • 10.3390/ani12141854
  8. Socha, Barbara M.; Socha, Piotr; Szóstek-Mioduchowska, Anna Z.; Nowak, Tomasz; Skarzynski, Dariusz J.. "Peroxisome proliferator-activated receptor expression in the canine endometrium with cystic endometrial hyperplasia–pyometra complex". Reproduction in Domestic Animals 57 7 (2022): 771-783. http://dx.doi.org/10.1111/rda.14121.
    Published • 10.1111/rda.14121
  9. Piotrowska-Tomala, Katarzyna K.; Jonczyk, Agnieszka W.; Szóstek-Mioduchowska, Anna Z.; Zebrowska, Ewelina; Ferreira-Dias, Graca; Skarzynski, Dariusz J.. "The Effects of Prostaglandin E2 Treatment on the Secretory Function of Mare Corpus Luteum Depends on the Site of Application: An in vivo Study". Frontiers in Veterinary Science 8 (2022): http://dx.doi.org/10.3389/fvets.2021.753796.
    Published • 10.3389/fvets.2021.753796
  10. Amaral, Ana; Fernandes, Carina; Szóstek-Mioduchowska, Anna; Lukasik, Karolina; Rebordão, Maria Rosa; Pinto-Bravo, Pedro; Skarzynski, Dariusz Jan; Ferreira-Dias, Graça. "The Inhibitory Effect of Noscapine on the In Vitro Cathepsin G-Induced Collagen Expression in Equine Endometrium". Life 11 10 (2021): 1107. http://dx.doi.org/10.3390/life11101107.
    10.3390/life11101107
  11. Wisniewska, Joanna; Sadowska, Agnieszka; Wójtowicz, Anna; Slyszewska, Magda; Szóstek-Mioduchowska, Anna. "Perspective on Stem Cell Therapy in Organ Fibrosis: Animal Models and Human Studies". Life 11 10 (2021): 1068. http://dx.doi.org/10.3390/life11101068.
    10.3390/life11101068
  12. Szóstek-Mioduchowska, Anna Z.; Shiotani, Haruki; Yamamoto, Yuki; Sadowska, Agnieszka; Wójtowicz, Anna; Kozai, Keisuke; Hojo, Takuo; et al. "Effects of cortisol on prostaglandin F2a secretion and expression of genes involved in the arachidonic acid metabolic pathway in equine endometrium - In vitro study". Theriogenology 173 (2021): 221-229. http://dx.doi.org/10.1016/j.theriogenology.2021.08.009.
    10.1016/j.theriogenology.2021.08.009
  13. Rebordão, Maria Rosa; Amaral, Ana; Fernandes, Carina; Silva, Elisabete; Lukasik, Karolina; Szóstek-Mioduchowska, Anna; Pinto-Bravo, Pedro; et al. "Enzymes Present in Neutrophil Extracellular Traps May Stimulate the Fibrogenic PGF2a Pathway in the Mare Endometrium". Animals 11 9 (2021): 2615. http://dx.doi.org/10.3390/ani11092615.
    10.3390/ani11092615
  14. Amaral, Ana; Fernandes, Carina; Szóstek-Mioduchowska, Anna; Rebordão, Maria Rosa; Skarzynski, Dariusz Jan; Ferreira-Dias, Graça. "Noscapine Acts as a Protease Inhibitor of In Vitro Elastase-Induced Collagen Deposition in Equine Endometrium". International Journal of Molecular Sciences 22 10 (2021): 5333. http://dx.doi.org/10.3390/ijms22105333.
    10.3390/ijms22105333
  15. Amaral, Ana; Fernandes, Carina; Rebordão, Maria Rosa; Szóstek-Mioduchowska, Anna; Lukasik, Karolina; Pinto-Bravo, Pedro; Telo da Gama, Luís; Jan Skarzynski, Dariusz; Ferreira-Dias, Graça. "Myeloperoxidase Inhibition Decreases the Expression of Collagen and Metallopeptidase in Mare Endometria under In Vitro Conditions". Animals 11 1 (2021): 208. http://dx.doi.org/10.3390/ani11010208.
    10.3390/ani11010208
  16. Amaral, Ana; Fernandes, Carina; Morazzo, Sofia; Rebordão, Maria Rosa; Szóstek-Mioduchowska, Anna; Lukasik, Karolina; Gawronska-Kozak, Barbara; et al. "The Inhibition of Cathepsin G on Endometrial Explants With Endometrosis in the Mare". Frontiers in Veterinary Science 7 (2020): http://dx.doi.org/10.3389/fvets.2020.582211.
    10.3389/fvets.2020.582211
  17. Bukowska, Joanna; Szóstek-Mioduchowska, Anna Zuzanna; Kopcewicz, Marta; Walendzik, Katarzyna; Machcinska, Sylwia; Gawronska-Kozak, Barbara. "Adipose-Derived Stromal/Stem Cells from Large Animal Models: from Basic to Applied Science". Stem Cell Reviews and Reports (2020): http://dx.doi.org/10.1007/s12015-020-10049-y.
    10.1007/s12015-020-10049-y
  18. Szóstek-Mioduchowska, Anna; Leciejewska, Natalia; Zelmanska, Beata; Staszkiewicz-Chodor, Joanna; Ferreira-Dias, Graça; Skarzynski, Dariusz. "Lysophosphatidic acid as a regulator of endometrial connective tissue growth factor and prostaglandin secretion during estrous cycle and endometrosis in the mare". BMC Veterinary Research 16 1 (2020): http://dx.doi.org/10.1186/s12917-020-02562-6.
    10.1186/s12917-020-02562-6
  19. Szóstek-Mioduchowska, Anna Zuzanna; Baclawska, Agnieszka; Rebordão, Maria Rosa; Ferreira-Dias, Graca; Skarzynski, Dariusz Jan. "Prostaglandins effect on matrix metallopeptidases and collagen in mare endometrial fibroblasts". Theriogenology 153 (2020): 74-84. http://dx.doi.org/10.1016/j.theriogenology.2020.04.040.
    10.1016/j.theriogenology.2020.04.040
  20. Piotrowska-Tomala, K.K.; Jonczyk, A.W.; Skarzynski, D.J.; Szóstek-Mioduchowska, A.Z.. "Luteinizing hormone and ovarian steroids affect in vitro prostaglandin production in the equine myometrium and endometrium". Theriogenology 153 (2020): 1-8. http://dx.doi.org/10.1016/j.theriogenology.2020.04.039.
    10.1016/j.theriogenology.2020.04.039
  21. Amaral, Ana; Fernandes, Carina; Rebordão, Maria Rosa; Szóstek-Mioduchowska, Anna; Lukasik, Karolina; Gawronska-Kozak, Barbara; Telo da Gama, Luís; Skarzynski, Dariusz J.; Ferreira-Dias, Graça. "The In Vitro Inhibitory Effect of Sivelestat on Elastase Induced Collagen and Metallopeptidase Expression in Equine Endometrium". Animals 10 5 (2020): 863. http://dx.doi.org/10.3390/ani10050863.
    10.3390/ani10050863
  22. Szóstek-Mioduchowska, Anna. "Neutrophils, monocytes and other immune components in the equine endometrium: Friends or foes?". Theriogenology (2020):
    10.1016/j.theriogenology.2020.01.018
  23. Szóstek-Mioduchowska, Anna. "Matrix metallopeptidase expression and modulation by transforming growth factor-ß1 in equine endometrosis". Scientific Reports 10 1 (2020): art. no 1119 (1-14).
    10.1038/s41598-020-58109-0
  24. Szóstek-Mioduchowska, Anna. "Effect of proinflammatory cytokines on endometrial collagen and metallopeptidase expression during the course of equine endometrosis". Cytokine 123 (2019): art. no 154767 (1-9).
    10.1016/j.cyto.2019.154767
  25. Szóstek-Mioduchowska, Anna. "Effect of transforming growth factor -ß1 on a-smooth muscle actin and collagen expression in equine endometrial fibroblasts". Theriogenology 124 (2019): 9-17.
    10.1016/j.theriogenology.2018.10.005
  26. Szóstek-Mioduchowska, Anna. "Evidence for increased content of PGF 2a , PGE 2 , and 6-keto-PGF 1a in endometrial tissue cultures from heavy draft mares in anestrus with endometritis". Journal of Equine Veterinary Science 77 (2019): 107-113.
    10.1016/j.jevs.2019.02.014
  27. Szóstek-Mioduchowska, Anna. "Impairment of anti-fibrotic PGE2 pathway may influence neutrophil extracellular traps-induced fibrosis in the mare endometrium". Domestic Animal Endocrinology 67 (2019): 1-10.
    10.1016/j.domaniend.2018.10.004
  28. Szóstek-Mioduchowska, Anna. "Expression profiling of selected miRNAs in equine endometrium in response to LPS challenge in vitro: a new understanding of the inflammatory immune response". Veterinary Immunology and Immunopathology 209 (2019): 37-44.
    10.1016/j.vetimm.2019.02.006
  29. Szóstek-Mioduchowska, Anna. "Effect of TGFß1, TGFß3 and keratinocyte conditioned media on functional characteristics of dermal fibroblasts derived from reparative (Balb/c) and regenerative (Foxn1 deficient; nude) mouse models". Cell and Tissue Research 374 1 (2018): 149-163.
    10.1007/s00441-018-2836-8
  30. Szóstek-Mioduchowska, Anna. "Elastase inhibition affects collagen transcription and prostaglandin secretion in mare endometrium during the estrous cycle". Reproduction in Domestic Animals 53 Suppl. 2 (2018): 66-69.
    10.1111/rda.13258
  31. Szóstek-Mioduchowska, Anna. "Constituents of neutrophil extracellular traps induce in vitro collagen formation in mare endometrium". Theriogenology 113 (2018): 8-18. https://doi.org/10.1016%2Fj.theriogenology.2018.02.001.
    10.1016/j.theriogenology.2018.02.001
  32. Szóstek-Mioduchowska, Anna. "Ovarian steroids, oxytocin, and tumor necrosis factor modulate equine oviduct function". Domestic Animal Endocrinology 61 (2017): 84-99.
    10.1016/j.domaniend.2017.06.005
  33. Szóstek-Mioduchowska, Anna. "Dual effect of hormones on mare reproductive physiology and dysfunction". Pferdeheilkunde 32 1 (2016): 36-38.
    10.21836/PEM20160106
  34. Szóstek-Mioduchowska, Anna. "The effect of coumestrol on progesterone and prostaglandin production in the mare: In vitro and in vivo studies". Biology of Reproduction 95 3 (2016):
    10.1095/biolreprod.116.138958
  35. Szóstek-Mioduchowska, Anna. "Type of inflammation differentially affects expression of interleukin 1ß and 6, tumor necrosis factor-a and toll-like receptors in subclinical endometritis in mares". PLoS ONE 11 5 (2016):
    10.1371/journal.pone.0154934
  36. Szóstek-Mioduchowska, Anna. "Evidence for a PGF2a auto-amplification system in the endometrium in mares". Reproduction 151 5 (2016): 517-526.
    10.1530/REP-15-0617
  37. Szóstek-Mioduchowska, Anna. "Bisphenol A modulates receptivity and secretory function of human decidual cells: An in vitro study". Reproduction 150 2 (2015): 115-125.
    10.1530/REP-14-0601
  38. Szóstek-Mioduchowska, Anna. "Opposing roles of leptin and Ghrelin in the equine corpus luteum regulation: An in vitro study". Mediators of Inflammation 2014 (2014):
    10.1155/2014/682193
  39. Szóstek-Mioduchowska, Anna. "LPS-challenged TNF a production, prostaglandin secretion, and TNF a /TNFRs expression in the endometrium of domestic cats in estrus or diestrus, and in cats with pyometra or receiving medroxyprogesterone acetate". Mediators of Inflammation 2014 (2014):
    10.1155/2014/689280
  40. Szóstek-Mioduchowska, Anna. "Ovarian steroid-dependent tumor necrosis factor-a production and its action on the equine endometrium in vitro". Cytokine 67 2 (2014): 85-91.
    10.1016/j.cyto.2014.02.005
  41. Szóstek-Mioduchowska, Anna. "Interleukins affect equine endometrial cell function: Modulatory action of ovarian steroids". Mediators of Inflammation 2014 (2014):
    10.1155/2014/208103
  42. Szóstek-Mioduchowska, Anna. "Novel luteolytic mechanisms in equine corpora lutea: the role of Nodal signaling pathway and its interaction with Tumor necrosis factor alpha, Interferon gamma and Fas ligand". Journal of Equine Veterinary Science 34 1 (2014): 117-119.
    10.1016/j.jevs.2013.10.080
  43. Szóstek-Mioduchowska, Anna. "What is new on the physiopathology of endometrosis in the mare?". Pferdeheilkunde 30 1 (2014): 15-18.
  44. Szóstek-Mioduchowska, Anna. "Placental origin of prostaglandin Fin the domestic cat". Mediators of Inflammation 2014 (2014):
    10.1155/2014/364787
  45. Szóstek-Mioduchowska, Anna. "The modulation of prostaglandin production by coumestrol in the equine endometrium in vitro". Journal of Equine Veterinary Science 34 1 (2014): 132-133.
    10.1016/j.jevs.2013.10.091
  46. Szóstek-Mioduchowska, Anna. "Ovarian steroids affect prostaglandin production in equine endometrial cells in vitro". Journal of Endocrinology 220 3 (2014): 263-276.
    10.1530/JOE-13-0185
  47. Szóstek-Mioduchowska, Anna. "Physiopathologic mechanisms involved in mare endometrosis". Reproduction in Domestic Animals 49 s4 (2014): 82-87.
    10.1111/rda.12397
  48. Szóstek-Mioduchowska, Anna. "Bisphenol A alters ß-hCG and MIF release by human placenta: An in vitro study to understand the role of endometrial cells". Mediators of Inflammation 2014 (2014):
    10.1155/2014/635364
  49. Szóstek-Mioduchowska, Anna. "Expression of aldo-keto reductase 1C23 in the equine corpus luteum in different luteal phases". Journal of Reproduction and Development 60 2 (2014): 150-154.
    10.1262/jrd.2013-120
  50. Szóstek-Mioduchowska, Anna. "Impairment of the interleukin system in equine endometrium during the course of endometrosis". Biology of Reproduction 89 4 (2013):
    10.1095/biolreprod.113.109447
  51. Szóstek-Mioduchowska, Anna. "Coumestrol and its metabolite in mares' plasma after ingestion of phytoestrogen-rich plants: Potent endocrine disruptors inducing infertility". Theriogenology 80 6 (2013): 684-692.
    10.1016/j.theriogenology.2013.06.002
  52. Szóstek-Mioduchowska, Anna. "Effect of cytokines and ovarian steroids on equine endometrial function: An in vitro study". Reproduction, Fertility and Development 25 7 (2013): 985-997.
    10.1071/RD12153
  53. Szóstek-Mioduchowska, Anna. "Role of tumor necrosis factor-a, interferon-¿ and Fas-ligand on in vitro nitric oxide activity in the corpus luteum". Cytokine 64 1 (2013): 18-21.
    10.1016/j.cyto.2013.07.015
  54. Szóstek-Mioduchowska, Anna. "Cytokines tumor necrosis factor-a and interferon-¿ participate in modulation of the equine corpus luteum as autocrine and paracrine factors". Journal of Reproductive Immunology 93 1 (2012): 28-37.
    10.1016/j.jri.2011.11.002
  55. Szóstek-Mioduchowska, Anna. "Cytokines and neutrophil extracellular traps in the equine endometrium: Friends or foes?". Pferdeheilkunde 28 1 (2012): 4-7.
    10.21836/PEM20120101
  56. Szóstek-Mioduchowska, Anna. "Steroidogenic capacity of the placenta as a supplemental source of progesterone during pregnancy in domestic cats". Reproductive Biology and Endocrinology 10 (2012):
    10.1186/1477-7827-10-89
  57. Szóstek-Mioduchowska, Anna. "MRNA transcription of prostaglandin synthases and their products in the equine endometrium in the course of fibrosis". Theriogenology 78 4 (2012): 768-776.
    10.1016/j.theriogenology.2012.03.024
  58. Szóstek-Mioduchowska, Anna. "Lipopolysaccharides, cytokines, and nitric oxide affect secretion of prostaglandins and leukotrienes by bovine mammary gland epithelial cells". Domestic Animal Endocrinology 43 4 (2012): 278-288.
    10.1016/j.domaniend.2012.04.005
  59. Szóstek-Mioduchowska, Anna. "Effects of cell storage and passage on basal and oxytocin-regulated prostaglandin secretion by equine endometrial epithelial and stromal cells". Theriogenology 77 8 (2012): 1698-1708.
    10.1016/j.theriogenology.2011.12.015
  60. Szóstek-Mioduchowska, Anna. "Is cortisol a modulator of interferon tau action in the endometrium during early pregnancy in cattle?". Journal of Reproductive Immunology 93 2 (2012): 82-93.
    10.1016/j.jri.2012.01.004
  61. Szóstek-Mioduchowska, Anna. "Ovarian steroids modulate tumor necrosis factor-a and nitric oxideregulated prostaglandin secretion by cultured bovine oviductal epithelial cells". Domestic Animal Endocrinology 41 1 (2011): 14-23.
    10.1016/j.domaniend.2011.01.007
  62. Szóstek-Mioduchowska, Anna. "Tumor necrosis factor-a inhibits the stimulatory effect of luteinizing hormone and prostaglandin E2 on progesterone secretion by the bovine corpus luteum". Domestic Animal Endocrinology 40 4 (2011): 183-191.
    10.1016/j.domaniend.2010.11.003
  63. Szóstek-Mioduchowska, Anna. "Nitric oxide stimulates progesterone and prostaglandin E2 secretion as well as angiogenic activity in the equine corpus luteum". Domestic Animal Endocrinology 40 1 (2011): 1-9.
    10.1016/j.domaniend.2010.08.001
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2023/10/27 The interaction between immune cells and extracellular matrix Polish-French seminar on the new regulation of reproduction: the role of adipokines.
2023/09/23 Zmiany w ekspresji enzymów DNMTs i TETs na poziomie mRNA w miesniówce macicy klaczy w przebiegu endometrosis Forum Hipologiczne im. Prof. Jerzego Zwolinskiego
2023/09/05 The role of immune cells in the pathogenesis of equine endometrosis Japan-Poland Joint Seminar. Cutting-edge Reproductive Physiology:Bridges to the Future of Research and Cooperation
(Morioka, Japan)
2022/06/27 Wplyw mediatorów stanu zapalnego na procesy zwiazane z rozwojem endometrosis u klaczy XI Konferencja Adeptów Fizjologii pt. „Adepci Fizjologii – Laczy Nas Pasja”
Olsztyn Branch of the Polish Physiological Society (Olsztyn, Poland)
2022/06/23 Transcriptomic analysis of mare endometrium reveals molecular changes in immune response and metabolism at different stages of endometrosis 5th International Conference on Uterine Disorders in Farm Animals: Endometritis as a cause of infertility in domestic animals
Institute of Animal Reproduction and Food Research of Polish Academy of Sciences
2021/11/26 Rola mediatorów zapalnych w procesach zwiazanych z rozwojem endometrosis u klaczy – badania in vitro XVI Kongres Polskiego Towarzystwa Nauk Weterynaryjnych PTNW
2021/09/27 The roles of inflammatory mediators in processes associated to the development of endometrosis in mare The 9th international Conference of Veterinary Divison; theme: Animal Health for Global Health Security
Cairo University
2019 The role of mediators of inflammation in the development of mare endometrosis 4th International Conference on endometritis in Cows and Mare” and “Joint Polish-Japanese Seminar “Cutting edge of reproductive physiology – key processes for birth of a new life”
(Warsaw, Poland)
2018 Transcriptome analysis of endometrial changes in the course of equine endometrosis 1st International Conference for Animal Genetics and Genomics.
(Olsztyn, Poland)
2015 MMP-2 and MMP-9 in equine endometrosis nternational Conference on Biology and Pathology of Reproduction in Domestic Animals
(Gdansk, Poland)
2015 Myofibroblast presence and their differentiation in the progression of equine endometrosis
(Miyazaki, Japan)
2014 Ovarian steroid-dependent tumor necrosis factor-a production and its action in equine endometrium in vitro XIth International Symposium on Equine Reproduction (ISER XI)
(Hamilton, New Zealand)
2013 Impairment of the endometrial interleukin and prostaglandin systems in chronic degenerative endometritis in the mare Refresh Workshop: Endometritis as a cause of infertility in domestic animals: new diagnostic and therapeutic strategies
(Olsztyn, Poland)
2012 Neutrophil extracellular traps formation and interleukin-1a and ß mRNA transcription in the equine endometrium
Reproduction in Domestic Animal (Berlin, Germany)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2021/10/01 - Current Understanding the molecular mechanisms of interactions between macrophages and endometrial fibroblasts in processes related to the pathogenesis of endometrosis in mares
Supervisor of Magda Slyszewska
2021/10/01 - Current Role of Macrophages type 1 and 2 in ECM remodeling under hypoxia condition in endometrosis in mares
Supervisor of Ewelina Zebrowska
2020/10/01 - Current The role of Th1 and Th2 helper cells in the pathogenesis of endometrosis in mares
Supervisor of Anna Wójtowicz
2023 - 2027 New approaches to equine endometrosis therapeutic strategy: The involvement of TGFß pathway
Co-supervisor of Marta Sofia Pavão Cerveira Pinto
2023 - 2024 The role of IL-12 in the pathogenesis of endometrosis in mare
Supervisor
2023 - 2024 Epigenetic changes in equine myometrium at different stages of endometrosis
Supervisor
2015 - 2016 Wplyw transformujacego czynnika wzrostu-ß1 na ekspresje metaloproteinaz i ich inhibitorów w komórkach nablonkowych blony sluzowej macicy klaczy
Supervisor
Uniwersytet Warminsko-Mazurski, Poland
2014 - 2015 Wplyw IL-1ß na ekspresje i uwalnianie metaloproteinaz podczas chronicznego degenerujacego zapalenia blony sluzowej macicy klaczy
Supervisor
Uniwersytet Warminsko-Mazurski, Poland
2014 - 2015 Czy kwas lizofosfatydowy bierze udzial w patogenezie endometrosis u klaczy?
Supervisor
Uniwersytet Warminsko-Mazurski, Poland
Distinctions

Award

2022 1st degree award for outstanding scientific achievement presented in the form of a monothematic series of works constituting the basis for conferring the academic habilitation awarded by the Polish Society of Veterinary Sciences, Warsaw, Poland.
2021 Distinction of the Branch of the Polish Academy of Sciences in Olsztyn and Bialystok for outstanding scientific achievements in the category of biological, agricultural and medical sciences

Other distinction

2014 Scholarship START dla Mlodych Naukowców¿
2014 Scholarship for young outstanding researcher Polish Ministry of Science and Higher Education
2012 Principals Scientific Award for Phd thesis Institute of Animal Reproduction and Food Research, Polish Academy of Science, Olsztyn, Poland.
2011 The grant for Ph.D students “DrINNO - increasing the supply of technology in the Warmia-Mazury through scholarships for phD students”
2008 The grant for Ph.D students “DrINNO - increasing the supply of technology in the Warmia-Mazury through scholarships for phD students”