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Sofia Isabel Domingues Combo. I am currently a Ph.D student in the Doctoral program of Pharmaceutical Sciences with specialization in Microbiology and Parasitology at the Faculty of Pharmacy, University of Coimbra since August 2020. I have completed the master's degree in Microbiology 2019/12/17 at the University of Aveiro and Degree in Biotechnology in 2017/09/18 at the Polytechnic Institute of Coimbra, Coimbra School of Agriculture. During my master's degree I made an internship at the Pathology Service of the Coimbra Hospital and University Center, more specifically in Microbiology, Serology and Molecular Biology Laboratories. I also made an internship under the European program "ERASMUS + mobility" in Poland at the University of Science and Technology, during my Biotechnology Degree. My areas of knowledge are Natural Sciences but mostly in Microbiology, including antimicrobial resistance, antibiotics, laboratory methodologies and in animal cell culture. For two year, I have been in Canada under the European program "ERASMUS + mobility" at the Calgary Univeristy, where I'm focusing on how can we use outer-membrane vesicles from Gram-negative bacteria to fight against Gram-negative bacteria.
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Identification

Personal identification

Full name
Sofia Isabel Domingues Combo

Citation names

  • Combo, Sofia

Author identifiers

Ciência ID
8518-EF90-B596
ORCID iD
0000-0002-5297-7337

Email addresses

  • sofiacombo@gmail.com (Professional)

Telephones

Mobile phone
  • 913343200 (Personal)

Addresses

  • Rua D. João I, nº113, Aviais, 3045-054, Coimbra, Coimbra, Portugal (Personal)

Knowledge fields

  • Natural sciences - Biological Sciences - Microbiology

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Spanish; Castilian Beginner (A1) Beginner (A1) Beginner (A1) Beginner (A1)
Education
Degree Classification
2020 - 2024
Ongoing
 Ciências Farmacêuticas (Doutoramento)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2022/02/22
Concluded
 Initial pedagogical training course for trainers (Outros)
Conclusão-Estudos e Formação Lda, Portugal
 Excelente
2021/02/01 - 2021/05/05
Concluded
 High-Throughput Screening (Outros)
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 17
2021/03/18 - 2021/03/22
Concluded
 Fighting infection (Outros)
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2021/01/18 - 2021/01/29
Concluded
 Core Technologies (Outros)
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2017/10/17 - 2019/12/17
Concluded
 Microbiologia (Mestrado)
Universidade de Aveiro, Portugal
"Bacteriologia e Virologia: Metodologias Laboratoriais de Ajuda ao Diagnóstico Clínico em Âmbito Hospitalar" (THESIS/DISSERTATION)
 15
2018/07/11 - 2018/07/11
Concluded
 Workshop Invasion and Migration (Outros)
Universidade de Coimbra - Faculdade de Medicina, Portugal
2014/09 - 2017/09/18
Concluded
 Biotecnologia (Licenciatura)
Instituto Politécnico de Coimbra Escola Superior Agrária de Coimbra, Portugal
"Evaluation of an optimal condition to genetically modify avian cells in vitro" (THESIS/DISSERTATION)
 13
2016/11/11 - 2016/11/18
Attended
 Competency based skills traning in Animal Research (Outros)
Universidade de Coimbra Faculdade de Medicina, Portugal

Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia, Portugal
2016/07/27 - 2016/08/01
Attended
 Scientific writing and communication (Outros)
Universidade de Aveiro Departamento de Biologia, Portugal

Universidade de Aveiro Centro de Estudos do Ambiente e do Mar, Portugal
2016/06/18 - 2016/06/22
Attended
 IV Cell Culture and Tissue Trainnig Course: Beyond the microscope, Culturing Life (Outros)
Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia, Portugal

Universidade de Coimbra Faculdade de Medicina, Portugal
Outputs

Publications

Conference poster
  1. Combo, Sofia; Sérgio G. Mendes; Domingues, Sara; Gabriela J. Da Silva. "Acinetobacter baumannii outer-membrane vesicles immunomodulate human pulmonary epithelial cells: effects of antimicrobial resistance". Paper presented in Biology Graduate Students' Association Symposium, 2024.
  2. Mendes, Sérgio; Combo, Sofia; Allain, Thibault; Domingues, Sara; Buret, Andre G.; Da Silva, Gabriela J.. "Antimicrobial resistance is associated with increased biofilm formation and altered motility in Acinetobacter baumannii". Paper presented in 10th Congress of European Microbiologists FEMS 2023, Hamburg, Germany, 2023.
  3. Combo, Sofia; Mendes, Sérgio; Allain, Thibault; Buret, Andre; Da Silva, Gabriela J.; Domingues, Sara. "Acinetobacter baumannii outer-membrane vesicles immunomodulate human pulmonary epithelial cells: Effects of antimicrobial resistance". Paper presented in 13th Symposium on the Biology of Acinetobacter, 2023.
  4. Mendes, Sérgio; Combo, Sofia; Allain, Thibault; Domingues, Sara; Buret, Andre G.; Da Silva, Gabriela J.. "Acquisition of ciprofloxacin resistance is associated with increased biofilm formation and altered motility in acinetobacter baumannii". Paper presented in 13th Symposium on the Biology of Acinetobacter, 2023.
Encyclopedia entry
  1. Combo, Sofia; Mendes, Sérgio; Nielsen, Kaare M.; Da Silva, Gabriela Jorge; Domingues, Sara. "The Role of Outer Membrane Vesicles against Bacteria". In Encyclopedia, 2023. https://encyclopedia.pub/entry/40874.
    Published
Journal article
  1. Sérgio G. Mendes; Combo, Sofia; Thibault Allain; Sara Domingues; Andre G. Buret; Gabriela J. Da Silva. "Co-regulation of biofilm formation and antimicrobial resistance in Acinetobacter baumannii: from mechanisms to therapeutic strategies". European Journal of Clinical Microbiology & Infectious Diseases (2023): https://doi.org/10.1007/s10096-023-04677-8.
    10.1007/s10096-023-04677-8
  2. Combo, Sofia; Sérgio Mendes; Kaare Magne Nielsen; Da Silva, G. J.; Sara Domingues. "The Discovery of the Role of Outer Membrane Vesicles against Bacteria". Biomedicines (2022): https://www.mdpi.com/2227-9059/10/10/2399.
    10.3390/biomedicines10102399
Thesis / Dissertation
  1. Combo, Sofia. "Bacteriologia e virologia: metodologias laboratoriais de ajuda ao diagnóstico clínico em âmbito hospitalar". Degree, Universidade de Aveiro Departamento de Biologia, 2019. https://ria.ua.pt/handle/10773/28348.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2019/12/17 Bacteriologia e Virologia: Metodologias Laboratoriais de Ajuda ao Diagnóstico Clínico em Âmbito Hospitalar Oral Presentation of Dissertation
Department of Biology of Aveiro University (Aveiro, Portugal)
2017 Evaluation of an optimal condition to genetically modify avian cells in vitro
University Of Science And Technology (Bydgoszcz, Poland)

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2022/10/01 - 2023/06/23 "13th International Simposium on the Biology of Acinetobacter": This International Symposium has as main goal to allow researchers to share and compare their results regarding Acinetobacter bacteria, one caused of nosocomial infections, that is listed as a priority one by WHO to develop novel therapies due to its increasing resistance. (2023/06/21 - 2033/06/23)
Symposium (Member of the Organising Committee)
 Universidade de Coimbra Faculdade de Farmácia, Portugal

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2021/09/17 - Current Exposição digital Microrganismos de Estimação
Exhibition
 Exposição digital Microrganismos de Estimação
Universidade de Coimbra Faculdade de Farmácia, Portugal

Universidade de Coimbra - Faculdade de Medicina, Portugal

Exploratório Centro Ciência Viva de Coimbra, Portugal
2017/12/06 - 2017/12/06 Concurso Regional Poliempreende - 14º Edição
Other
 Concurso Regional Poliempreende - 14º Edição
Rede Nacional dos Institutos Politécnicos, Portugal
Distinctions

Award

2024 Best Poster Presentation
University of Calgary Department of Biological Sciences, Canada