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Samira Ferreira graduated in Biochemistry in 2008 and obtained her PhD in Health Sciences in 2012 at the University of Coimbra. She is a Junior Researcher at the Center for Innovation and Biomedicine (CIBB), University of Coimbra. She is interested in the role of neuromodulators, particularly adenosine and endocannabinoids on the regulation of synaptic transmission, neural plasticity and behavior. She has a total of 29 peer-reviewed publications, from which 3 are as first author and 5 as last author. She has been the main supervisor of a total of 3 master students, mentored 2 PhD students, 2 master students, and several Bachelor's degree students, as well as MSc students in lab rotations. She has been a jury member in 2 PhD thesis and the main examiner in 2 master thesis. She is yearly invited to teach classes related to her research topics and technical expertise across 6 different master programmes and 1 bachelor's degree at the University of Coimbra. She has co-organized several events, including a one-day symposium on the variability and adaptation in neurons and circuits held in 2016, a two-day international symposium on medical cannabis and role of endocannabinoids in health and disease, held in March 2023, and the 2023 Retreat of the Neuroscience & Disease Research Line at CIBB (to be held on June 2). She is a member of the Portuguese Neuroscience Society (SPN), the Portuguese Pharmacological Society (SPF) and the International and European Neurochemical Society (ISN and ESN).
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Identification

Personal identification

Full name
Samira Cardoso Lopes Ferreira

Citation names

  • Ferreira, Samira G.

Author identifiers

Ciência ID
861B-D36C-2EC9
ORCID iD
0000-0001-7486-5056

Telephones

Telephone
  • 239820190 (Professional)

Addresses

  • CNC-UC, Polo I, Universidade de Coimbra, Rua Larga, FMUC Building, 1st and 2nd floors , 3004-504, Coimbra, Coimbra, Portugal (Professional)

Knowledge fields

  • Medical and Health Sciences - Health Sciences

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Education
Degree Classification
2013/04 - 2019/01
Concluded
 Adenosinergic and dopaminergic modulation in the medial prefrontal cortex – implications for ADHD (Pós-doutoramento)
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2016/07 - 2016/07
Concluded
 Visiting researcher at the laboratory of Dr. Laurent Venance (Outros)
Collège de France, France
2014/08 - 2014/08
Concluded
 Visiting researcher at the laboratory of Nuno Sousa and João Oliveira, ICVS/3Bs (Outros)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2012
Concluded
 Doutoramento em Ciências da Saúde (Ramo de Ciências Biomédicas) (Doutoramento)
Universidade de Coimbra Faculdade de Medicina, Portugal
"Presynaptic A2A adenosine receptors control CB1 cannabinoid receptor-mediated effects at corticostriatal nerve terminals" (THESIS/DISSERTATION)
 Aprovada com Distinção e Louvor
2011/01 - 2011/12
Concluded
 Visiting PhD student at Inserm U667, Collège de France, Paris, France, under the supervision of Dr. Laurent Venance. (Outros)
Collège de France, France
2009/09 - 2009/11
Concluded
 Visiting PhD student at the School of Medical Sciences, University of Aberdeen, Scotland, under the supervision of Professor Tibor Harkany. (Outros)
University of Aberdeen, United Kingdom
2008
Concluded
 Bioquimica (Licenciatura)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"Control of striatal input terminals by fatty acid dopamides in rodents" (THESIS/DISSERTATION)
 15
Affiliation

Science

Category
Host institution 		Employer
2019/01/19 - Current Contracted Researcher (Research) Centro de Inovação em Biomedicina e Biotecnologia (CIBB), Portugal
Projects

Grant

Designation Funders
2019/10/01 - Current [La Caixa Foundation] Adenosine A2A receptors as a new opportunity to manage and detail the neurobiology of emotional distress (PI: Rodrigo A. Cunha)
adostress (CPD0027A02#IV0027)
Researcher
Ongoing
2018 - Current Adenosine A2A receptors as triggers of memory dysfunction in Alzheimers disease: mechanisms and therapeutic prospects
COMPETE/FCT/CCDRC/Portugal 2020
Post-doc Fellow
Ongoing
2014 - Current Neuroprotection by adenosine receptors
MB-98-2014
Post-doc Fellow
2014 - Current Role of adenosine A2A receptors in different brain circuits, impact on reward and fear responses
NARSAD
Post-doc Fellow
Concluded
2011 - Current New treatments for stress-induced dysregulation of circuits regulating reward, fear, and habit learning
DARPA-09-68-ESR-FP-010
Post-doc Fellow
Concluded
2013/01/01 - 2014/12/31 Synaptic mechanisms involved in the brain cannabinoid actions and their modulation by adenosine receptors: implications for memory and mood control
info:eu-repo/grantAgreement/FCT/COMPETE/132990/PT
Post-doc Fellow
Universidade do Algarve Faculdade de Ciências e Tecnologia
2010/03/17 - 2012/07/31 Mapping the metabolic and neuromodulator role of insulin in the hippocampus
info:eu-repo/grantAgreement/FCT/5876-PPCDTI/105663/PT
PhD Student Fellow
Universidade do Algarve Faculdade de Ciências e Tecnologia
Concluded
2010/03/17 - 2012/06/16 Demonstrating that A2A adenosine receptors control glutamatergic synaptic plasticity through CB1 cannabinoid receptors in the striatum, thus providing attracting therapeutic targets
info:eu-repo/grantAgreement/FCT/5876-PPCDTI/100729/PT
PhD Student Fellow
Universidade do Algarve Faculdade de Ciências e Tecnologia
2007 - 2007 Interactions between the purinergic and endocannabinoid systems in pain sensation
TÉT-GRICES PT-18/2007
Other
Concluded

Contract

Designation Funders
2018/07/01 - 2021/06/30 Recetores A2A da adenosina como desencadeadores de disfunção mnemónica na doença de Alzheimer: mecanismos e possibilidade terapêutica
PTDC/MED-NEU/31274/2017
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2010/03/17 - 2012/06/16 Demonstração de que os receptores de adenosina A2A controlam a plasticidade sináptica glutamatergica via dos receptores de canabinóide CB1 no corpo estriado, fornecendo assim alvos terapêuticos atrativos
PTDC/SAU-NEU/100729/2008
University of Aberdeen Institute of Medical Sciences, United Kingdom

Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Conference poster
  1. Ferreira, Samira G.. "Samira G. Ferreira et al. Pivotal role of adenosine A2A receptors in the amygdala in the control of repeated stress- induced alterations". Paper presented in Society for Neuroscience, 2022.
  2. Ferreira, Samira G.. "Chronic blockade of adenosine A2A receptors revert prefrontal cortex synaptic plasticity deficits induced by binge-like exposure to ethanol in adolescent female rats". Paper presented in 8th European Synapse Meeting, 2022.
  3. Ferreira, Samira G.. "Samira G. Ferreira et al. Adenosine A2A receptor antagonism does not correct synaptic and behavioral deficits in the spontaneously hypertensive rat model of attention deficit and hyperactivity disorder". Paper presented in XVII Meeting of the Portuguese Society for Neuroscience, 1-3 December 2021, Coimbra, Portugal, 2021.
  4. Matilde S. Rodrigues. "Matilde S. Rodrigues, Rodrigo A. Cunha, Sergi Ferré, Samira G. Ferreira, Attila Köfalvi 2020. Reduced A1/A2A Adenosine Receptor Ratio in Corticostriatal Terminals in a Rat Model of Restless Legs Syndrome.". Paper presented in XVII. Meeting of the Portuguese Society for Neuroscience. 1-3 December 2020 Coimbra, Portugal, 2020.
  5. Anna Pliássova. "Anna Pliassova, Samira G. Ferreira, Henrique B. Silva, Rodrigo A. Cunha. Adenosine A2AR receptors selectively control synaptic plasticity in the amygdala without affecting NMDA receptors. 11th FENS Forum of Neuroscience. 7 – 11 July 2018, Berlin, Germany.". 2018.
  6. Samira G. Ferreira. "Amber Kerkhofs, Samira Ferreira, Joana Real, Carolina Xavier, Paula Canas, Huibert Mansvelder, Rodrigo Cunha. Adenosine A2A receptor controls long-term potentiation in rodent and human cortical areas. 7th ISN Special Neurochemistry Conference on Synaptic Function and Disfunction In Brain Diseases. June 1st – 4th, 2016, Coimbra, Portugal.". 2016.
    10.1109/nebc.2002.999455
  7. Amber Kerkhofs. "A. Kerkhofs, S. G. Ferreira, J. I. Real, C. Xavier, P. M. Canas, N. Gonçalves, H. D. Mansvelder, R. A. Cunha. Adenosine A2A receptor controls long-term potentiation in the rodent and human cortex. 10th FENS Forum of Neuroscience. July 2nd – 6th, 2016, Copenhagen, Denmark.". 2016.
  8. Ferreira, Samira G.. "Samira G. Ferreira, Douglas Leffa, Nélio Gonçalves, Nuno J. Machado, Carolina Souza, Joana I. Real, Pablo Pandolfo, Rodrigo A. Cunha. Adenosine A2A receptors (A2AR) in the medial prefrontal cortex control long-term potentiation and impulsive behavior – interaction with dopamine D2-like receptors. Gordon Research Conferemce on Catecholamines (GRS), August 9th – 14th, 2015. Newry ME, USA.". 2015.
  9. S. Henriques. "S. Henriques, L. Caetano, P. Patrício, C. Cunha, A. Mateus-Pinheiro, N. D. Alves, F. Baptista, A. R. Santos, S. G. Ferreira, V. Sardinha, J. F. Oliveira, N. Sousa, A. F. Ambrósio, A. J. Rodrigues, R. A. Cunha, L. Pinto, Catarina A. Gomes. Chronic anxiety caused by antenatal immunomodulation is paralleled by an atrophy of microglial processes in the pre-frontal cortex of female rats.". Paper presented in XIV meeting of the Portuguese Society for Neuroscience, 2015.
  10. Joana I. Real. "Joana I. Real, S. G. Ferreira, T. Silva, P. Agostinho, R. A. Cunha. Ecto-5’-nucleotidase (CD73)-generated adenosine activates adenosine A2A receptors to control long-term potentiation in the mouse prelimbic medial prefrontal cortex. XIV meeting of the Portuguese Society for Neuroscience. June 4-5 2015. Póvoa de Varzim, Portugal.". 2015.
  11. Ferreira, Samira G.. "A. Kerkhofs, Samira G. Ferreira, J. I. Real, C. Xavier, P. M. Canas, N. Gonçalves, H. D. Mansvelder, R. A. Cunha. Adenosine A2A receptors selectively control long-term potentiation in rodent prelimbic medial prefrontal cortex and human cortical areas. XIV meeting of the Portuguese Society for Neuroscience. June 4-5 2015. Póvoa de Varzim, Portugal.". 2015.
  12. Sherida de Leeuw. "Sherida de Leeuw, Amber Kerkhofs, Joana Real, Samira Ferreira, Rodrigo Cunha, Huib Mansvelder. The Adenosine A1 Receptor controls basal synaptic activity in the PFC. Annual meeting, Neuroscience Campus Amsterdam, April 23rd, 2015.". 2015.
  13. Amber Kerkhofs. "Amber Kerkhofs, S. G. Ferreira, J. I. Real, C. Xavier, P. M. Canas, R. A. Cunha, H. D. Mansvelder. Adenosine A2A receptors selectively control long-term potentiation in rodent prelimbic medial prefrontal cortex and human cortical areas. Annual ENC Network meeting April, 27th-28th 2015. Coimbra, Portugal.". 2015.
  14. Ferreira, Samira G.. "Samira G. Ferreira, D. Leffa, N. Gonçalves, C. Souza, N. J. Machado, P. Pandolfo, R. A. Cunha. Blockade/downregulation of the adenosine A2A receptors elicits impulsive phenotype and impairs long-term potentiation in the prelimbic medial prefrontal cortex – relationship with dopamine D2-like receptors. XVIII Congress of the Portuguese Biochemical Society. December 18th – 20th, 2014. Coimbra, Por". 2014.
  15. Ferreira, Samira G.. "Samira G. Ferreira, D. Leffa, N. Gonçalves, C. Souza, N. J. Machado, P. Pandolfo, R. A. Cunha. Adenosine A2A receptors control impulsivity and synaptic plasticity in the prelimbic medial prefrontal cortex - interaction with dopamine D2-like receptors. SfN annual meeting, 2014. November 15th – 19th. Washington D.C., USA.". 2014.
  16. Ferreira, Samira G.. "Ferreira S.G., Pandolfo P., Bittencourt, R. M.; Teixeira, F. M.; Nunes-Correia, I.; Takahashi, R. N.; Venance, L.; Harkany, T.; Cunha, R. A.; Köfalvi, A. Pre- and Postsynaptic A2A Adenosine Receptors Control Endocannabinoid Signaling at Corticostriatal Terminals. XXVI Reunião Anual da FeSBE. August 26th 2011. Rio de Janeiro, Brasil.". 2011.
    10.4025/5cih.pphuem.2103
  17. Ferreira, Samira G.. "Ferreira S., Bitencourt R.M., Garção P., Queiroz F., Tomé A., Nunes-Correia I, Ledent C, Venance L., Cunha R.A & Köfalvi A. Presynaptic A2A adenosine receptors control CB1 cannabinoid receptors at corticostriatal nerve terminals. 8th FENS Forum of Neuroscience. July 14th-18th 2011. Barcelona, Spain.". 2011.
  18. Ferreira, Samira G.. "Samira G. Ferreira, Rafael M. Bitencourt, Pablo Pandolfo, Filipe M. Teixeira, Isabel Nunes-Correia, Reinaldo N. Takahashi, Tibor Harkany, Rodrigo A. Cunha, and Attila Köfalvi. Pre and post-synaptic A2A adenosine receptors control endocannabinoid signaling at corticostriatal terminals. Gordon Research conferences - Cannabinoid Function in the CNS May 22, 2011 - May 27, 2011. Les Diablerets, Swit". 2011.
  19. Ferreira, Samira G.. "Samira G. Ferreira, Rodrigo A. Cunha, and Attila Köfalvi. Presynaptic A2A adenosine and CB1 cannabinoid receptors inhibit the function of one another at corticostriatal terminals. Purines 2010. May 30th – June 2nd. Tarragona-Barcelona, Spain.". 2010.
  20. Ferreira, Samira G.. "Samira G. Ferreira, Alberto Martire, Maria Teresa Tebano, Valentina Chiodi, Ken Mackie, Rodrigo A. Cunha, Patrizia Popoli, Attila Köfalvi. Presynaptic adenosine A2A receptors control cannabinoid CB1 receptor-mediated inhibition of striatal glutamatergic neurotransmission. 11th meeting of the Portuguese Society for Neuroscience. June 4-6 2009. Braga, Portugal.". 2009.
  21. Attila Köfalvi. "Samira C. Ferreira, László Köles, Zoltán Zádori, Attila Köfalvi. Fatty acid-dopamide-sensitive cation channels control striatal input terminals. Annual meeting of ENI-NET European Neuroscience Institutes Network. 05.19-05.21 2008. Warsaw, Poland.". 2008.
  22. Ghisleni CG. "Ghisleni CG, Duarte JM, Samira C. Ferreira, Carvalho RA, Jones JG, Oliveira CR, Cunha RA, Köfalvi A. CB1 cannabinoid receptors control glucose homeostasis and intermediary metabolism in the hippocampus. 2nd Gordon Research Conference on Cannabinoid Function in the CNS. 09.30-10.05 2007 Geneva, Switzerland". 2007.
Journal article
  1. Masella, Gianluca; Silva, Francisca; Corti, Elisa; Azkona, Garikoitz; Madeira, Maria Francisca; Tomé, Ângelo R.; Ferreira, Samira G.; et al. "The amygdala NT3-TrkC pathway underlies inter-individual differences in fear extinction and related synaptic plasticity". Molecular Psychiatry (2024): http://dx.doi.org/10.1038/s41380-024-02412-z.
    Accepted • 10.1038/s41380-024-02412-z
  2. Cátia R. Lopes; Joana S. Silva; Joana Santos; Matilde S. Rodrigues; Daniela Madeira; Andreia Oliveira; Ana Moreira-de-Sá; et al. "Downregulation of Sirtuin 1 Does Not Account for the Impaired Long-Term Potentiation in the Prefrontal Cortex of Female APPswe/PS1dE9 Mice Modelling Alzheimer's Disease". International Journal of Molecular Sciences (2023): https://www.mdpi.com/1422-0067/24/8/6968.
    10.3390/ijms24086968
  3. Cátia R. Lopes; Andreia Oliveira; Ingride Gaspar; Matilde S. Rodrigues; Joana Santos; Eszter Szabó; Henrique B. Silva; et al. "Effects of Chronic Caffeine Consumption on Synaptic Function, Metabolism and Adenosine Modulation in Different Brain Areas". Biomolecules (2023): https://www.mdpi.com/2218-273X/13/1/106.
    10.3390/biom13010106
  4. Dias, L.; Pochmann, D.; Lemos, C.; Silva, H.B.; Real, J.I.; Gonçalves, F.Q.; Rial, D.; et al. "Increased Synaptic ATP Release and CD73-Mediated Formation of Extracellular Adenosine in the Control of Behavioral and Electrophysiological Modifications Caused by Chronic Stress". ACS Chemical Neuroscience 14 7 (2023): 1299-1309. http://www.scopus.com/inward/record.url?eid=2-s2.0-85149749803&partnerID=MN8TOARS.
    10.1021/acschemneuro.2c00810
  5. Rodrigues, Matilde S.; Ferreira, Samira G.; Quiroz, César; Earley, Christopher J.; García-Borreguero, Diego; Cunha, Rodrigo A.; Ciruela, Francisco; Köfalvi, Attila; Ferré, Sergi. "Brain Iron Deficiency Changes the Stoichiometry of Adenosine Receptor Subtypes in Cortico-Striatal Terminals: Implications for Restless Legs Syndrome". Molecules 27 5 (2022): 1489. http://dx.doi.org/10.3390/molecules27051489.
    10.3390/molecules27051489
  6. Simões, A.P.; Gonçalves, F.Q.; Rial, D.; Ferreira, S.G.; Lopes, J.P.; Canas, P.M.; Cunha, R.A.. "CD73-Mediated Formation of Extracellular Adenosine Is Responsible for Adenosine A2A Receptor-Mediated Control of Fear Memory and Amygdala Plasticity". International Journal of Molecular Sciences 23 21 (2022): http://www.scopus.com/inward/record.url?eid=2-s2.0-85141606599&partnerID=MN8TOARS.
    10.3390/ijms232112826
  7. Pinheiro, B.G.; Luz, D.A.; Cartágenes, S.D.C.; Fernandes, L.D.M.P.; Farias, S.V.; Kobayashi, N.H.C.; Fontes-Júnior, E.A.; et al. "The Role of the Adenosine System on Emotional and Cognitive Disturbances Induced by Ethanol Binge Drinking in the Immature Brain and the Beneficial Effects of Caffeine". Pharmaceuticals 15 11 (2022): http://www.scopus.com/inward/record.url?eid=2-s2.0-85141780548&partnerID=MN8TOARS.
    10.3390/ph15111323
  8. Speck, Ana E.; Aguiar, Aderbal S.; Ferreira, Samira G.; Silva, Henrique B.; Tomé, Angelo R.; Agostinho, Paula; Cunha, Rodrigo A.; Prediger, Rui D.. "Exercise decreases aberrant corticostriatal plasticity in an animal model of L-DOPA-induced dyskinesia". American Journal of Physiology-Regulatory, Integrative and Comparative Physiology (2021): http://dx.doi.org/10.1152/ajpregu.00295.2020.
    10.1152/ajpregu.00295.2020
  9. Pliássova, Anna; Henriques, Margarida; Silva, Henrique B.; Agostinho, Paula; Cunha, Rodrigo A.; Ferreira, Samira G.. "Control of NMDA Receptor-Mediated Currents by Adenosine A1 and A2A Receptors Within the Basolateral Amygdala". Journal of Caffeine and Adenosine Research 10 2 (2020): 61-70. http://dx.doi.org/10.1089/caff.2019.0024.
    10.1089/caff.2019.0024
  10. Köfalvi, A.; Moreno, E.; Cordomí, A.; Cai, N.-S.; Fernández-Dueñas, V.; Ferreira, S.G.; Guixà-González, R.; et al. "Control of glutamate release by complexes of adenosine and cannabinoid receptors". BMC Biology 18 1 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85078265363&partnerID=MN8TOARS.
    10.1186/s12915-020-0739-0
  11. Pedro, J.R.; Moura, L.I.F.; Valério-Fernandes, Â.; Baptista, F.I.; Gaspar, J.M.; Pinheiro, B.S.; Lemos, C.; et al. "Transient gain of function of cannabinoid CB1 receptors in the control of frontocortical glucose consumption in a rat model of Type-1 diabetes". Brain Research Bulletin 161 (2020): 106-115. http://www.scopus.com/inward/record.url?eid=2-s2.0-85085035596&partnerID=MN8TOARS.
    10.1016/j.brainresbull.2020.05.004
  12. Gonçalves, Francisco Q.; Lopes, João P.; Silva, Henrique B.; Lemos, Cristina; Silva, António C.; Gonçalves, Nélio; Tomé, Ângelo R.; et al. "Synaptic and memory dysfunction in a ß-amyloid model of early Alzheimer's disease depends on increased formation of ATP-derived extracellular adenosine". Neurobiology of Disease 132 (2019): 104570. http://dx.doi.org/10.1016/j.nbd.2019.104570.
    10.1016/j.nbd.2019.104570
  13. Leffa, Douglas T.; Ferreira, Samira G.; Machado, Nuno J.; Souza, Carolina M.; Rosa, Fernanda da; de Carvalho, Cristiane; Kincheski, Grasielle C.; et al. "Caffeine and cannabinoid receptors modulate impulsive behavior in an animal model of attentional deficit and hyperactivity disorder". European Journal of Neuroscience (2019): http://dx.doi.org/10.1111/ejn.14348.
    10.1111/ejn.14348
  14. Duarte, J.M.; Gaspar, R.; Caetano, L.; Patrício, P.; Soares-Cunha, C.; Mateus-Pinheiro, A.; Alves, N.D.; et al. "Region-specific control of microglia by adenosine A2A receptors: uncoupling anxiety and associated cognitive deficits in female rats". GLIA 67 1 (2019): 182-192. http://www.scopus.com/inward/record.url?eid=2-s2.0-85056875204&partnerID=MN8TOARS.
    10.1002/glia.23476
  15. Real, J.I.; Simões, A.P.; Cunha, R.A.; Ferreira, S.G.; Rial, D.. "Adenosine A2Areceptors modulate the dopamine D2receptor-mediated inhibition of synaptic transmission in the mouse prefrontal cortex". European Journal of Neuroscience (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85044642309&partnerID=MN8TOARS.
    10.1111/ejn.13912
  16. Kerkhofs, A.; Canas, P.M.; Timmerman, A.J.; Heistek, T.S.; Real, J.I.; Xavier, C.; Cunha, R.A.; Mansvelder, H.D.; Ferreira, S.G.. "Adenosine A2Areceptors control glutamatergic synaptic plasticity in fast spiking interneurons of the prefrontal cortex". Frontiers in Pharmacology 9 MAR (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85044114631&partnerID=MN8TOARS.
    10.3389/fphar.2018.00133
  17. Kerkhofs, A.; Xavier, A.C.; da Silva, B.S.; Canas, P.M.; Idema, S.; Baayen, J.C.; Ferreira, S.G.; Cunha, R.A.; Mansvelder, H.D.. "Caffeine controls glutamatergic synaptic transmission and pyramidal neuron excitability in human neocortex". Frontiers in Pharmacology 8 JAN (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85040453826&partnerID=MN8TOARS.
    10.3389/fphar.2017.00899
  18. Leffa, D.T.; Pandolfo, P.; Gonçalves, N.; Machado, N.J.; de Souza, C.M.; Real, J.I.; Silva, A.C.; et al. "Adenosine A2A receptors in the rat prelimbic medial prefrontal cortex control delay-based cost-benefit decision making". Frontiers in Molecular Neuroscience 11 (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85059003991&partnerID=MN8TOARS.
    10.3389/fnmol.2018.00475
  19. Caetano, L.; Pinheiro, H.; Patrício, P.; Mateus-Pinheiro, A.; Alves, N.D.; Coimbra, B.; Baptista, F.I.; et al. "Adenosine A 2A receptor regulation of microglia morphological remodeling-gender bias in physiology and in a model of chronic anxiety". Molecular Psychiatry 22 7 (2017): 1035-1043. http://www.scopus.com/inward/record.url?eid=2-s2.0-84991030115&partnerID=MN8TOARS.
    10.1038/mp.2016.173
  20. Ferreira, S.G.; Gonc¸alves, F.Q.; Marques, J.M.; Tomé, Â.R.; Rodrigues, R.J.; Nunes-Correia, I.; Ledent, C.; et al. "Presynaptic adenosine a2A receptors dampen cannabinoid CB1 receptor-mediated inhibition of corticostriatal glutamatergic transmission". British Journal of Pharmacology 172 4 (2015): 1074-1086. http://www.scopus.com/inward/record.url?eid=2-s2.0-84921682826&partnerID=MN8TOARS.
    10.1111/bph.12970
  21. Bitencourt, R.M.; Alpár, A.; Cinquina, V.; Ferreira, S.G.; Pinheiro, B.S.; Lemos, C.; Ledent, C.; et al. "Lack of presynaptic interaction between glucocorticoid and CB1 cannabinoid receptors in GABA- and glutamatergic terminals in the frontal cortex of laboratory rodents". Neurochemistry International 90 (2014): 72-84. http://www.scopus.com/inward/record.url?eid=2-s2.0-84947029342&partnerID=MN8TOARS.
    10.1016/j.neuint.2015.07.014
  22. Köles, L.; Garção, P.; Zádori, Z.S.; Ferreira, S.G.; Pinheiro, B.S.; da Silva-Santos, C.S.; Ledent, C.; Köfalvi, A.. "Presynaptic TRPV1vanilloid receptor function is age- but not CB1cannabinoid receptor-dependent in the rodent forebrain". Brain Research Bulletin 97 (2013): 126-135. http://www.scopus.com/inward/record.url?eid=2-s2.0-84880816335&partnerID=MN8TOARS.
    10.1016/j.brainresbull.2013.06.007
  23. Duarte, J.M.N.; Ferreira, S.G.; Carvalho, R.A.; Cunha, R.A.; Köfalvi, A.. "CB1receptor activation inhibits neuronal and astrocytic intermediary metabolism in the rat hippocampus". Neurochemistry International 60 1 (2012): 1-8. http://www.scopus.com/inward/record.url?eid=2-s2.0-83455224661&partnerID=MN8TOARS.
    10.1016/j.neuint.2011.10.019
  24. Lemos, C.; Valério-Fernandes, Â.; Ghisleni, G.C.; Ferreira, S.G.; Ledent, C.; de Ceballos, M.L.; Köfalvi, A.. "Impaired hippocampal glucoregulation in the cannabinoid CB1receptor knockout mice as revealed by an optimized in vitro experimental approach". Journal of Neuroscience Methods 204 2 (2012): 366-373. http://www.scopus.com/inward/record.url?eid=2-s2.0-84855251226&partnerID=MN8TOARS.
    10.1016/j.jneumeth.2011.11.028
  25. Richter, H.; Teixeira, F.M.; Ferreira, S.G.; Kittel, Á.; Köfalvi, A.; Sperlágh, B.. "Presynaptic a2-adrenoceptors control the inhibitory action of presynaptic CB1cannabinoid receptors on prefrontocortical norepinephrine release in the rat". Neuropharmacology 63 5 (2012): 784-797. http://www.scopus.com/inward/record.url?eid=2-s2.0-84864451017&partnerID=MN8TOARS.
    10.1016/j.neuropharm.2012.06.003
  26. Ferreira, S.G.; Teixeira, F.M.; Garção, P.; Agostinho, P.; Ledent, C.; Cortes, L.; MacKie, K.; Köfalvi, A.. "Presynaptic CB1 cannabinoid receptors control frontocortical serotonin and glutamate release - Species differences". Neurochemistry International 61 2 (2012): 219-226. http://www.scopus.com/inward/record.url?eid=2-s2.0-84863463752&partnerID=MN8TOARS.
    10.1016/j.neuint.2012.05.009
  27. Mulder, J.; Zilberter, M.; Pasquaré, S.J.; Alpár, A.; Schulte, G.; Ferreira, S.G.; Köfalvi, A.; et al. "Molecular reorganization of endocannabinoid signalling in Alzheimer's disease". Brain 134 4 (2011): 1041-1060. http://www.scopus.com/inward/record.url?eid=2-s2.0-79953672641&partnerID=MN8TOARS.
    10.1093/brain/awr046
  28. Martire, A.; Tebano, M.T.; Chiodi, V.; Ferreira, S.G.; Cunha, R.A.; Köfalvi, A.; Popoli, P.. "Pre-synaptic adenosine A2A receptors control cannabinoid CB 1 receptor-mediated inhibition of striatal glutamatergic neurotransmission". Journal of Neurochemistry 116 2 (2011): 273-280. http://www.scopus.com/inward/record.url?eid=2-s2.0-78650714744&partnerID=MN8TOARS.
    10.1111/j.1471-4159.2010.07101.x
  29. Ferreira, S.G.; Lomaglio, T.; Avelino, A.; Cruz, F.; Oliveira, C.R.; Cunha, R.A.; Köfalvi, A.. "N-acyldopamines control striatal input terminals via novel ligand-gated cation channels". Neuropharmacology 56 3 (2009): 676-683. http://www.scopus.com/inward/record.url?eid=2-s2.0-58749097218&partnerID=MN8TOARS.
    10.1016/j.neuropharm.2008.12.001
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2023/02/03 Madalena Piteira, Sarah Viana, Joana Santos, João P. Lopes, Cátia R. Lopes, Pedro Valada, Joana Silva, Ângelo R. Tomé, Bruno G. Pinheiro, Cristiane S.F. Maia, Rodrigo A. Cunha and Samira G. Ferreira. Chronic blockade of adenosine A2A receptors revert prefrontal cortex synaptic plasticity deficits induced by binge-like exposure to ethanol in adolescent female rats 53rd Meeting of the Portuguese Society of Pharmacology, 41st Meeting of Clinical Pharmacology and 22nd Meeting of Toxicology
Portuguese Society of Pharmacology (Coimbra, Portugal)
2023/02/02 Margarida Nabais, Liliana Dias, Samira Ferreira, Joana Silva, Rodrigo A. Cunha, Paula AgostinhoImpact of restraint stress on the density of aquaporin 4 and kir4.1: putative modulation by adenosine A2A receptors. 53rd Meeting of the Portuguese Society of Pharmacology, 41st Meeting of Clinical Pharmacology and 22nd Meeting of Toxicology
Portuguese Society of Pharmacology (Coimbra, Portugal)
2023/02/02 Cátia R. Lopes, Andreia Oliveira, Ingride Gaspar, Matilde S. Rodrigues, Joana Santos, Eszter Szabó, Henrique B. Silva, Ângelo R. Tomé, Paula M. Canas, Paula Agostinho, Rui A. Carvalho, Rodrigo A. Cunha, Ana Patrícia Simões, João Pedro Lopes, Samira G. Ferreira. Effects of chronic caffeine consumption on synaptic function and adenosine modulation. 53rd Meeting of the Portuguese Society of Pharmacology, 41st Meeting of Clinical Pharmacology and 22nd Meeting of Toxicology
Portuguese Society of Pharmacology (Coimbra, Portugal)
2020 Anna Pliassova, Samira Ferreira, Margarida Henriques, Pedro Valada, Paula Agostinho, Rodrigo A. Cunha. Effect of repeated restraint stress on synaptic transmission in the basolateral complex of the amygdala - role of adenosine A2A receptors. 50.ª Reunião da Sociedade Portuguesa de Farmacologia, 38.ª Reunião de Farmacologia Clínica e 19.ª Reunião de Toxicologia. 5th – 7th February 2020, Coimbra, Portugal.
2019 Douglas T. Leffa, Pablo Pandolfo, Nélio Gonçalves, Nuno J. Machado, Carolina M. de Souza, Joana I. Real, António C. Silva, Henrique B. Silva, Attila Köfalvi, Rodrigo A. Cunha, Samira G. Ferreira. Adenosine A2A receptors in the rat prelimbic medial prefrontal cortex control delay-based cost-benefit decision making. XLIX Reunião Sociedade Portuguesa De Farmacologia XXXVII Reunião Farmacologia Clínica XVIII Reunião Toxicologia. FEBRUARY 6th ,7th, 8th, 2019, Faculty of Pharmacy University of Porto, Portugal
2019 Anna Pliássova, Samira G. Ferreira, Margarida Henriques, Henrique B. Silva, Inês Marques-Morgado, Luísa V. Lopes, Paula Agostinho, Rodrigo A. Cunha. Control of synaptic plasticity and of nmda receptor function by adenosine A2A receptors in the amygdala. XLIX Reunião Sociedade Portuguesa De Farmacologia XXXVII Reunião Farmacologia Clínica XVIII Reunião Toxicologia. FEBRUARY 6th ,7th, 8th, 2019, Faculty of Pharmacy University of Porto, Portugal
2019 Anna Pliassova, Samira Ferreira, Pedro Valada, Paula Agostinho, Rodrigo A. Cunha. Physio(patho)logical role of A2A receptors in the amygdala. VIII annual PHDOC meeting, 30th October 2019, Coimbra, Portugal.
2018 Anna Pliássova, Samira G. Ferreira, Henrique B. Silva, Rodrigo A. Cunha. XLVII Reunião Anual da Sociedade Portuguesa de Farmacologia; XXXV Reunião de Farmacologia Clínica; XLVIII Reunião Anual da Sociedade Portuguesa de Farmacologia; XXXVI Reunião de Farmacologia Clínica; XVII Reunião de Toxicologia. February 5th – 7th, 2018, Lisbon, Portugal.
2017 Amber Kerkhofs, Samira G. Ferreira, Joana I. Real, Carolina Xavier, Paula M. Canas, Huibert D. Mansvelder, Rodrigo A. Cunha. A2A adenosine receptors control long-term potentiation in pyramidal neurons and interneurons in the prelimbic medial prefrontal cortex of wistar rats. XLVII Reunião Anual da Sociedade Portuguesa de Farmacologia; XXXV Reunião de Farmacologia Clínica; XVI Reunião de Toxicologia. February 2nd – 4th, 2017, Coimbra, Portugal.
2017 Margarida Henriques, Rodrigo A. Cunha, Samira G. Ferreira. adenosine A2A receptors and dopamine D2-like receptors share common mechanisms to control long-term potentiation in the prelimbic medial prefrontal cortex of wistar rats. XLVII Reunião Anual da Sociedade Portuguesa de Farmacologia; XXXV Reunião de Farmacologia Clínica; XVI Reunião de Toxicologia. February 2nd – 4th, 2017, Coimbra, Portugal.
2017 Francisco Q. Gonçalves, João Pedro Lopes, Daniel Rial, Samira G. Ferreira, Nélio Gonçalves, Paula M. Canas, Rodrigo A. Cunha. ATP-derived adenosine is responsible forthe activation of neuronal A2A receptors to facilitate long-term potentiation in themouse hippocampus. XLVII Reunião Anual da Sociedade Portuguesa de Farmacologia; XXXV Reunião de Farmacologia Clínica; XVI Reunião de Toxicologia. February 2nd – 4th, 2017, Coimbra, Portugal.
2017 Joana Mendes Duarte, Liliana Caetano, Patrícia Patrício, Carina Cunha, António Mateus-Pinheiro, Nuno Dinis Alves, Ana Rita Santos, Samira G. Ferreira, Vanessa Sardinha, João Filipe Oliveira, Rita Gaspar, Nuno Sousa, Rodrigo Antunes Cunha, António Francisco Ambrósio, Ana João Rodrigues, Luísa Pinto, Catarina A. Gomes. divergent pattern of microglia morphology across the brain: uncoupling anxiety and cognition by blocking adenosine A2A receptors. XLVII Reunião Anual da Sociedade Portuguesa de Farmacologia; February 2nd – 4th, 2017, Coimbra, Portugal.
2017 Attila Köfalvi, Ning-Sheng Cai, Hideaki Yano, Estefania Moreno, Vicent Casadó, Samira G. Ferreira, Ana Maria Sebastião, Rodrigo A Cunha, Sergi Ferré. allosteric modulations of g protein-mediated signaling within the A2AR-CB1R heterotetramer. XLVII Reunião Anual da Sociedade Portuguesa de Farmacologia; XXXV Reunião de Farmacologia Clínica; XVI Reunião de Toxicologia. February 2nd – 4th, 2017, Coimbra, Portugal.
2016 Samira Ferreira. Complexity of adenosinergic modulation in the prefrontal cortex. 6th PostDoc Forum Symposium: Variability and adaptation in neurons and circuits. June 1st, 2016, Coimbra, Portugal.
2016 Anna Pliássova, Samira Ferreira, Rodrigo Cunha. Dissecting the transducing systems involved in the control of long-term potentiation (LTP) in the amygdala by the A2A adenosine receptors (A2AR). Retreat PhDOC Ageing and Chronic Diseases. October 14th – 15th, 2016, Coimbra, Portugal.
2015 Samira G. Ferreira, Garção P., Bitencourt R., Ledent C., Cunha R. A., Köfalvi A. The adenosine A2A receptor is critical for the cannabinoid CB1 receptor-mediated inhibition of striatal GABA release. Annual meeting of the Portuguese Pharmacological Society, February 5th – 6th, 2015. Lisbon, Portugal.
2015 Samira G. Ferreira, Douglas Leffa, Nélio Gonçalves, Nuno J. Machado, Carolina Souza, Joana I. Real, Pablo Pandolfo, Rodrigo A. Cunha. Adenosine A2A receptors (A2AR) in the medial prefrontal cortex control long-term potentiation and impulsive behavior – interaction with dopamine D2-like receptors. Gordon Research Seminar on Catecholamines (GRS), August 8th – 9th, 2015. Newry ME, USA.
2015 Samira Ferreira. Efeitos da cafeína no cérebro. VI Encontro de Jovens Investigadores Cabo-Verdianos, December 18th – 20th, 2015, Lisbon, Portugal.
2014 Samira Ferreira. Adapting to an ever-changing landscape. 2nd Postdoc day at The University of Coimbra. October 30th 2014. Coimbra, Portugal.
2014 Samira G. Ferreira, Douglas Leffa, Nélio Gonçalves, Nuno J. Machado, Carolina Souza, Pablo Pandolfo, Rodrigo A. Cunha. Medial prefrontal cortex adenosine A2A receptors control long-term potentiation and impulsive behavior – interaction with dopamine d2-like receptors. XII CNC meeting, December 15th – 16th, 2014. Coimbra, Portugal.
2011/12 Samira G. Ferreira, Rafael M. Bitencourt, Pablo Pandolfo, Isabel Nunes, Reinaldo N. Takahashi, Laurent Venance, Tibor Harkány, Rodrigo A. Cunha and Attila Köfalvi. Presynaptic A2A adenosine receptors control endocannabinoid signaling at corticostriatal terminals. IX CNC meeting, December 19th – 20th, 2011. Coimbra, Portugal.

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2022/09 - Current Dissecting the role of adenosine A2A receptors on neurobehavioral deficits induced by binge-like exposure to ethanol during adolescence
Supervisor
 Master’s degree in Cellular and Molecular Biology (Master)
Universidade de Coimbra, Portugal
2021/09/15 - 2022/09/22 Chronic intermittent ethanol and caffeine exposure during adolescence: impact on prefrontal cortex physiology and behavior
Supervisor
 Mestrado em Biologia Celular e Molecular (Master)
Universidade de Coimbra, Portugal
2016 - 2017 Modulation of NMDA receptor currents by adenosine A2A receptors in the Schaffer collaterals-CA1 synapses
Supervisor
 Master in Cellular and Molecular Biology
Universidade de Coimbra Departamento de Ciências da Vida, Portugal

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2023/06/02 - 2023/06/02 2023 Retreat of the Neuroscience & Disease Research Line at CIBB. Participation of All Neuroscience and Disease research groups. (2023/06/02 - 2023/06/02)
Meeting
 Centro de Inovação em Biomedicina e Biotecnologia (CIBB), Portugal
2023/03/09 - 2023/03/10 Clearing the smoke on Medical Cannabis: the importance of the endocannabinoid system in health and disease (2023/03/09 - 2023/03/10)
Conference (Co-organisor)
 Centro de Inovação em Biomedicina e Biotecnologia (CIBB), Portugal
2016/06/01 - 2016/06/01 6th CNC.IBILI PostDoc Forum Symposium: Variability and adaptation in neurons and circuits. (2016/06/01 - 2016/06/01)
Symposium (Co-organisor)
2014 - 2016 One of the coordinators of the Wondrous Wednesdays Postdoc Science Club – as part of the CNC.IBILI Postdoc Forum - informal scientific discussions between postdocs to foster intra-institutional collaborations, held once every two months. (2014 - 2016)
Seminar (Co-organisor)
2013/10/30 - 2013/10/30 1st Postdoc Day at the University of Coimbra (2013/10/30)
Meeting (Member of the Organising Committee)
 Universidade de Coimbra, Portugal

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2023/04/26 Synaptic Regulation By Chronic Stress-Induced microRNAs
(Thesis) Arguer
 Beatriz Figueiredo Rodrigues (PhD)
Universidade de Coimbra, Portugal
2022/09/22 Impact of chronic blockade of adenosine A2A receptors on neurobehavioral changes induced by intermittent ethanol exposure in adolescent female rats - focus on the prefrontal cortex
Supervisor
 Joana Martins Duarte Santos (Master)
Universidade de Coimbra, Portugal
2022/09/16 The impact of early life stress on anxiety and depression later in life: the contribution of MeCP2
(Thesis) Main arguer
 Maria Francisca Jesus Damas Santos Madeira (Master)
Universidade de Coimbra, Portugal
2021/03 Pathophysiological role of adenosinergic modulation within the basolateral complex of the amygdala
(Thesis) Arguer
 Anna Vladimirovna Pliassova (PhD)
Universidade de Coimbra, Portugal
2020/12/11 Microglia Morphology and Behavior upon Testosterone Administration of Females Prenatally Exposed to Dexamethasone
(Thesis) Main arguer
 Alexandra Filipa Figueiredo Cruz (Master)
Universidade de Coimbra, Portugal

Association member

Society Organization name Role
2023/02/13 - Current European Society for Neurochemistry (ESN) and International Society for Neurochemistry (ISN)
2017/02/03 - Current Portuguese Pharmacological Society
2009/06/16 - Current Portuguese Neuroscience Society
2015 - 2016 Postdoc Representatives at CNC.IBILI (now CIBB), University of Coimbra Elected Deputy Postdoc Representative at the CNC.IBILI

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2023/11/08 - 2024/11/08 Basic principles of electrophysiology - 1 hour class (Mestrado) Universidade de Coimbra Faculdade de Medicina, Portugal
2024/01/31 - 2024/01/31 Prefrontal cortex function & plasticity in psychiatric conditions - 1h30' class (Mestrado) Universidade de Coimbra Faculdade de Medicina, Portugal
2024/01/29 - 2024/01/29 Methods to study synapses (synaptosomes/electrophysiology) - 1h30' class (Mestrado) Universidade de Coimbra Faculdade de Medicina, Portugal
2024/01/16 - 2024/01/16 Circuits for executive control - 1h30' class (Mestrado) Universidade de Coimbra Departamento de Ciências da Vida, Portugal
2023/11/08 - 2023/11/08 Basic principles of electrophysiology - 3-hour practical class (acute hippocampal slices, fEPSP, LTP and LTD protocols) (Mestrado) Universidade de Coimbra Faculdade de Medicina, Portugal
2023/05/02 - 2023/05/02 Ethanol & the brain - molecular features & therapeutic interventions (Neurofarmacologia (02003618) - MBIOQ, MEB, MIEBIOM) - 3h30 Neurofarmacologia (Mestrado) Universidade de Coimbra, Portugal
2023/01/23 - 2023/01/23 Circuits For Executive Control - 1h (Circuitos Neuronais e Comportamento (02035364) - Master programmes MBC, MBCM, MNMT) Neuronal circuits and behavior (Mestrado) Universidade de Coimbra, Portugal
2023/01/04 - 2023/01/04 Prefrontal cortex function & plasticity in psychiatric conditions (Neurofisiologia e Cognição (02038136) Master programme MNMT) - 1h30 Neurofisiologia e Cognição (Mestrado) Universidade de Coimbra, Portugal
2023/01/02 - 2023/01/02 Methods to study synapses (Synaptosomes / Electrophysiology) (Neurofisiologia e Cognição (02038136) - MNMT) - 1h30 Neurofisiologia e Cognição
2022/11/09 - 2022/11/09 Electrophysiology (Tecnologias de Investigação em Neurobiologia (02003561) - Master programmes MEB, MIEBIOM) - 1h Neurofisiologia e Cognição (Mestrado) Universidade de Coimbra, Portugal
2022/11/09 - 2022/11/09 Electrophysiology rigs and procedures for extracellular and whole-cell patch-clamp recordings in rodent brain slices (Tecnologias de Investigação em Neurobiologia (02003561) - Master programmes MEB, MIEBIOM) - 3h Research Technologies in Neurobiology (Mestrado) Universidade de Coimbra, Portugal
2022/01/18 - 2022/01/18 Circuits for executive function (1 hour class) Master in Cell and Molecular Biology (Mestrado) Universidade de Coimbra, Portugal
2021/11/25 - 2021/11/25 Prefrontal cortex function & plasticity in psychiatric conditions (1h30 class) Master in Molecular and Translational Neurosciences (Mestrado) Universidade de Coimbra, Portugal
2021/11/22 - 2021/11/22 Methods to study synapses (synaptosomes/electrophysiology) (1h30 class) Masters in Molecular and Translational Neurosciences (Mestrado) Universidade de Coimbra, Portugal
2021/04/27 - 2021/04/27 Prefrontal cortex function & plasticity in psychiatric conditions (3h30 class) Master in Biomedical Engeneering (Mestrado integrado) Universidade de Coimbra, Portugal
2021/01/14 - 2021/01/14 prefrontal cortex function & plasticity in psychiatric conditions - 1-hour invited lecture. Course "Synaptic function, neurophysiology and cognition" Master in Molecular and Translational Neurosciences (Mestrado) Universidade de Coimbra Faculdade de Medicina, Portugal
2020/12/10 - 2020/12/10 Crircuits for executive control - 1-hour invited lecture for the course "Neuronal circuits and behavior" Master in Cellular and Molecular Biology (Mestrado) Universidade de Coimbra Departamento de Ciências da Vida, Portugal
2019/12/12 - 2019/12/12 Circuits for executive control - 1.5-hour invited lecture Master in Cellular and Mollecular Biology (Mestrado) Universidade de Coimbra Departamento de Ciências da Vida, Portugal
2019/11/27 - 2019/11/27 Intracellular messengers and integration of signalling pathways - 1.5 hour-invited lecture Mestrado integrado em Engenharia Biomédica (Mestrado integrado) Universidade de Coimbra, Portugal
2019/11/25 - 2019/11/25 Cellular receptors - 1.5-hour invited lecture Mestrado Integrado em Engenharia Biomédica (Mestrado integrado) Universidade de Coimbra Faculdade de Medicina, Portugal
2017/01/09 - 2017/01/09 Role of A2A adenosine receptors in the control of synaptic transmission, plasticity and behaviour - 2-hour invited lecture Master in Cellular and Mollecular Biology (Mestrado) Universidade de Coimbra Departamento de Ciências da Vida, Portugal
2016/11/21 - 2016/11/21 Role of prefrontal cortex A2A adenosine receptors on synaptic transmission, plasticity and behavior - 1-hour inveted lecture Ciências Biomédicas (Licenciatura) Universidade do Algarve Departamento de Ciências Biomédicas e Medicina, Portugal
2016/11/09 - 2016/11/09 Princípios básicos de electrofisiologia - 1-hour invited lecture Mestrado Integrado em Engenharia Biomédica (Mestrado integrado) Universidade de Coimbra Faculdade de Medicina, Portugal
2016/11/09 - 2016/11/09 Registos electrofisiológicos extracelulares e "whole-cell patch-clamp" em fatias agudas de cérebro de roedores: circuitos do hipocampo e do córtex pré-frontal - 3-hour practical / hands on course Mestrado Integrado em Engenharia Biomédica (Mestrado integrado) Universidade de Coimbra Faculdade de Medicina, Portugal
2016/01/04 - 2016/01/04 Electrophysiological and behavioral effects of A2A adenosine receptors in the prefrontal cortex - 2 hour invited lecture Master in Cellular and mollecular Biology (Mestrado) Universidade de Coimbra Departamento de Ciências da Vida, Portugal

Mentoring / Tutoring

Topic Student name
2023/10/01 - Current Impact of Adenosine A2A receptors on binge-like ethanol exposure during adolescence Maria Sousa
2022/01/24 - Current Long-term adenosine A2A receptor blockade decreases early withdrawal neurobehavioral impairments induced by binge-like ethanol consumption in female adolescent rats Sarah Viana
2024/01/03 - 2024/01/29 Impact of chronic blockade of adenosine A2A receptors (A2AR) in an animal model of chronic stress Madalena Almeida
2021/09 - 2022/09 Impact of chronic stress on A2AR control of amygdala function Ingride Luzio Gaspar
2022/04 - 2022/07 Effects of adenosine receptors activity on reserpine- induced electrophysiological changes in the striatum Jorge Pedrosa
2022/01 - 2022/06 Chronic intermittent ethanol and caffeine exposure during adolescence: impact on prefrontal cortex physiology and behavior Sarah Viana
2022/02/01 - 2022/02 3 weeks Lab rotation, with evaluation - Master in Cell and Molecular Biology, University of Coimbra Yelko Bejarano
2021/03/13 - 2021/12/31 A2AR in PFC parvalbumin interneurons from healthy and stressed animals Matilde Rodrigues
2019/09 - 2020/11 Hypoadenosinergic pathologies in a rat model of the willis-ekbom disease (Restless Leg Syndrome) Matilde Sofia Guerreiro da Costa Rodrigues
2015 - 2020 Pathophysiological role of adenosine receptors in the basolateral amygdala Anna Pliássova
2013 - 2018 Role of adenosine receptors on synaptic transmission and plasticity in rodent prefrontal cortex and human cortical areas Amber Kerkhofs
2016/05 - 2016/06 mGluR5-mediated decrease in evoked NMDA EPSC Margarida Henriques
2016/05 - 2016/06 Studying the interaction of mGluR5 and NMDA receptors in the CA1 of hippocampus Muluken Mamo
2016/03 - 2016/06 Electrophysiological effects of caffeine in the prefrontal cortex José Pinto
2015/05 - 2015/06 Role of adenosine A2A receptors in the Wistar rat prelimbic medial prefrontal cortex Débora Serrenho
Distinctions

Other distinction

2015 International Travel Grant to attend Gordon Research Conference on Catecholamines
International Brain Research Organization, France
2012 Postdoctoral fellowship - SFRH/BPD/85738/2012
Fundação para a Ciência e a Tecnologia, Portugal
2008 PhD fellowship - SFRH / BD / 33467 / 2008
2003 A five year undergraduate fellowship