Carlos David Lourenço Lima (871C-DEB7-7B4F)

Curriculum Vitae

Carlos David Lourenço Lima

I am a young researcher that took the BSc degree in Biochemistry (2015-2018), and immediately after, I started my MSc in Biochemistry (2018-2021), finishing with a score of 17 out of 20 at NOVA School of Science and Technology. During these years, I actively participated in the organization of academic events, as well as being a member of multiple associations such as AEFCT and NuBioq. During the last year, I developed my Master thesis entitled "Deciphering the structural features of LacdiNAc interaction with lectins using NMR spectroscopy". In the last 3 months of the thesis, I was awarded with a scholarship in the program "Escola de Verão UCIBIO". I finished my Master thesis with a score of 19 out of 20 and this work resulted in 1 paper in Chemistry-A European Journal, where I am the first author. This work allowed me to work with many national/international specialists in the areas of carbohydrates such as Prof. Dr. Jesús Jiménez-Barbero (Spain) and Prof. Dr. Francisco Corzana (Spain), and also Dr. Ana Luísa Carvalho (Portugal) which is a crystallography specialist. I started my PhD in Biochemistry in 2021, winning a scholarship from FCT in the Chemistry panel.

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Identification

Personal identification

Full name: Carlos David Lourenço Lima

Citation names

Lima, Carlos D. L.

Author identifiers

Ciência ID: 871C-DEB7-7B4F
ORCID iD: 0000-0001-7031-4564

Knowledge fields

Exact Sciences - Chemical Sciences
Natural sciences - Biological Sciences - Biochemistry
Natural sciences - Biological Sciences - Molecular Biology

Languages

Language	Speaking	Reading	Writing	Listening	Peer-review
Portuguese (Mother tongue)
English	Advanced (C1)	Advanced (C1)	Advanced (C1)	Advanced (C1)

Education

	Degree	Classification
2021/05 - 2025 Ongoing	Bioquímica (Doutoramento) Major in Biochemistry Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal Universidad de la Rioja Departamento de Química, Spain
2018/09 - 2021/01/21 Concluded	Bioquímica (Mestrado integrado) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal "Deciphering the structural features of glycan-lectin interactions in the immune system" (THESIS/DISSERTATION)	17/20
2015/09 - 2018/07/02 Concluded	Bioquímica (Licenciatura) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal	14/20
2008/09 - 2010/05 Concluded	Master Windows Ultimate (Outros) Major in Informática Unicenter Skills Gym, Portugal	85/100

Projects

Grant

	Designation	Funders
2021/10/01 - Current	Exploiting human macrophage galactose-type lectin interactions towards cancer therapies 2021.06789.BD PhD Student Fellow Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal Universidad de la Rioja Departamento de Química, Spain	Fundação para a Ciência e a Tecnologia Ongoing
2020/07/28 - 2020/10/26	Molecular Recognition of LacdiNAc and LacNAc by Human Macrophage Galactose-type Lectin (MGL) Escola de Verão UCIBIO Research Fellow REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal	Fundação para a Ciência e a Tecnologia Concluded

Contract

	Designation	Funders
2021/01/01 - 2025/12/31	Institute for Health and Bioeconomy LA/P/0140/2020 10.54499/LA/P/0140/2020 PhD Student Fellow Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal Universidade de Lisboa Instituto de Bioengenharia e Biociências, Portugal Universidade Nova de Lisboa, Portugal INESC Microsistemas e Nanotecnologias, Portugal Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal Universidade Nova de Lisboa Associação para a Inovação e Desenvolvimento da FCT, Portugal Unidade de Ciências Biomoleculares Aplicadas, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2020/01/01 - 2023/12/31	Applied Molecular Biosciences Unit UIDB/04378/2020 10.54499/UIDB/04378/2020 PhD Student Fellow Universidade Nova de Lisboa, Portugal Unidade de Ciências Biomoleculares Aplicadas, Portugal Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal Universidade Nova de Lisboa Associação para a Inovação e Desenvolvimento da FCT, Portugal Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente, Portugal Universidade do Porto, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2020/01/01 - 2023/12/31	Applied Molecular Biosciences Unit UIDP/04378/2020 10.54499/UIDP/04378/2020 PhD Student Fellow Universidade Nova de Lisboa, Portugal Unidade de Ciências Biomoleculares Aplicadas, Portugal Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal Universidade Nova de Lisboa Associação para a Inovação e Desenvolvimento da FCT, Portugal Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente, Portugal Universidade do Porto, Portugal	Fundação para a Ciência e a Tecnologia Concluded

Outputs

Publications

Conference poster	Lima, Carlos D. L.; Johnson, Simon E.; Grosso, Ana Sofia; Dias, Jorge S; Cabrita, Eurico; Corzana, Francisco; Galan, Carmen; Marcelo, Filipa. "Targeting Human Macrophage Galactose C-type Lectin with a multivalent GalNAc mimetic". Paper presented in 14th International Meeting of the Portuguese Carbohydrate Group - GLUPOR14, 2023. Lima, Carlos D. L.; Coelho, Helena (F913-034A-A51B); Gimeno, Ana; Trovão, Filipa (AC11-1704-9BF8); Diniz, Ana (251C-31C4-4A91); Dias, Jorge S (851A-6502-159B); Jiménez-Barbero, Jesús; et al. "Deciphering the molecular recognition mechanism between human immune related lectins and the cancer and pathogenic glycobiomarker LacdiNAc". Paper presented in Summer School in Biomedical Glycoscience, 2022. Lima, Carlos D. L.; Coelho, Helena; Gimeno, Ana; Trovão, Filipa; Diniz, Ana; Dias, Jorge S; Jiménez-Barbero, Jesús; et al. "Understanding the difference on molecular recognition of LacdiNAc by immune-related lectins". Paper presented in 9th IberoAmerican NMR meeting (presented by Carlos D. L. Lima), 2021. Lima, Carlos D. L.; Diniz, Ana; Dias, Jorge S; Cabrita, Eurico J.; Marcelo, Filipa. "Deciphering the structural features of LacdiNAc interaction with lectins using NMR spectroscopy". Paper presented in 1º Meeting COST Action CA18132 (GLYCOnanoPROBES) (presented by Carlos D. L. Lima), 2019.
Journal article	Lima, Carlos D. L.; Coelho, Helena; Gimeno, Ana; Trovão, Filipa; Diniz, Ana; Dias, Jorge S.; Jiménez-Barbero, Jesús; et al. "Structural Insights into the Molecular Recognition Mechanism of the Cancer and Pathogenic Epitope, LacdiNAc by Immune-Related Lectins". Chemistry – A European Journal 27 29 (2021): 7951-7958. http://dx.doi.org/10.1002/chem.202100800. Published • 10.1002/chem.202100800
Thesis / Dissertation	Lima, Carlos D. L.. "Deciphering the structural features of glycan-lectin interactions in the immune system". Master, Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, 2021. Lima, Carlos D. L.. "Isomanida com Propriedades Fotocrómicas". Degree, Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, 2018.

Activities

Oral presentation

	Presentation title	Event name Host (Event location)
2022/07/12	Unravelling the molecular recognition of the cancer and pathogenic glycobiomarker LacdiNAc by human immune-related lectins	IUBMB–FEBS–PABMB Congress Portuguese Biochemical Society (Lisbon, Portugal)
2021/10/06	Deciphering the mechanism behind the molecular recognition of the cancer epitope, LacdiNAc, by lectins of the immune system	6 th Latin American Glycobiology Congress Latin American Society of Glycobiology (Mexico City, Mexico)
2020/12/08	Deciphering the structural features of LacdiNAc recognition by lectins of immune system using NMR spectroscopy	EUROMAR, A European Magnetic Resonance Meeting CICbioGUNE (Bilbao, Spain)

Event organisation

	Event name Type of event (Role)	Institution / Organization
2018/11/06 - 2019/02/08	Organisation of the Biochemistry JorTec (2019/02/08 - 2019/02/08) Seminar (Member of the Organising Committee)	Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2018/03/03 - 2018/04/11	Organisation of ExpoFCT on behalf of NuBioq (2018/04/11 - 2018/04/11) Exhibition (Member of the Organising Committee)	Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Event participation

	Activity description Type of event	Event name Institution / Organization
2021/04/26 - 2021/04/29	9th IberoAmerican NMR meeting Meeting	9th IberoAmerican NMR meeting Instituto de Química Avanzada de Cataluña, Spain
2020/12/07 - 2020/12/08	EUROMAR, A European Magnetic Resonance Meeting Meeting	EUROMAR, A European Magnetic Resonance Meeting CIC bioGUNE, Spain
2020/02/07 - 2020/02/07	Participation in the Biochemistry JorTec Seminar	Biochemistry JorTec Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2019/11/18 - 2019/11/20	1º Meeting COST Action CA18132 (GLYCOnanoPROBES) (Caparica, Portugal) Meeting	1º Meeting COST Action CA18132 (GLYCOnanoPROBES) (Caparica, Portugal) REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2019/09/04 - 2019/09/06	Participation in the 1º NOVABiophysica Conference	NOVA Biophysica Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2018/03/23 - 2018/03/26	Participation in the National Meeting of Biochemistry Students Meeting	XI ENEBIOQ Universidade do Porto Faculdade de Ciências, Portugal
2018/02/02 - 2018/02/02	Participation in the Biochemistry JorTec Seminar	Biochemistry JorTec Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2017/04/07 - 2017/04/10	Participation in the National Meeting of Biochemistry Students Meeting	X ENEBIOQ Universidade do Minho, Portugal
2017/02/10 - 2017/02/10	Participation in the Biochemistry JorTec Seminar	Biochemistry JorTec Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Association member

	Society Organization name	Role
2018/01 - 2020/09	NuBioq	Member of Direction
2018/08 - 2019/08	NuBioq	Coordenator of Recreational Area
2016/09 - 2018/08	NuBioq	Member of Recreational Area
2017/01 - 2018/01	Student Association of Faculdade de Ciências e Tecnologia	Colaborator of the Image Area
2016/10 - 2017/10	Pedagogical Commision of the degree in Biochemistry	Member

Course / Discipline taught

	Academic session	Degree Subject (Type)	Institution / Organization
2022/06/08 - 2022/06/10	Summer School in Biomedical Glycoscience		GEHIC-RSEQ, Spain

Distinctions

Award

2021	2021 Call for PhD Studentships Fundação para a Ciência e a Tecnologia, Portugal
2020	Scholarship in "Escola de Verão UCIBIO" Fundação para a Ciência e a Tecnologia, Portugal REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
2015	18th place nationally in Canguru Matemático (Category: Estudante) Universidade de Coimbra Departamento de Matemática, Portugal
2012	9th place nationally in Canguru Matemático (Category: Cadete) Universidade de Coimbra Departamento de Matemática, Portugal