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Ana Rita Garizo graduated in Biology and has a master's degree in Human Biology and Environment completed at the Faculty of Sciences, University of Lisbon in 2014 and 2016, respectively. Currently, she has a PhD degree in Biotechnology and Biosciences completed at the Instituto Superior Técnico, University of Lisbon in 2021. Her PhD studies had as main aim the development of a drug delivery nanosystem for lung cancer therapy. The thesis was developed in the Biological Sciences Research Group of the Institute for Bioengineering and Biosciences (iBB) at Instituto Superior Técnico, University of Lisbon, and in the Nanomedicines & Translational Drug Delivery Group (N&TDD) of the Institute for Research and Innovation in Health (i3S), University of Porto.
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Identification

Personal identification

Full name
Ana Rita Cebola Garizo

Citation names

  • Garizo, Ana Rita

Author identifiers

Ciência ID
8915-2A02-519B
ORCID iD
0000-0003-3399-5844

Email addresses

  • anagarizo@tecnico.ulisboa.pt (Professional)

Knowledge fields

  • Medical and Health Sciences - Medical Biotechnology - Health-Related Biotechnology
  • Engineering and Technology - Nano-technology
  • Natural sciences - Biological Sciences - Cell Biology

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
English Intermediate (B1) Intermediate (B1) Intermediate (B1) Intermediate (B1)
Education
Degree Classification
2017/03/01 - 2021/09/24
Concluded
 Biotecnologia e Biociências (Doutoramento)
Universidade de Lisboa Instituto Superior Técnico, Portugal

Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
"The anticancer potential of the bacterial protein azurin and its derived peptides: mode of action and development of a nanosized drug delivery system for lung cancer therapy " (THESIS/DISSERTATION)
 Pass with Distinction
2016
Concluded
 Human Biology and Environment (Mestrado)
Universidade de Lisboa Faculdade de Ciências, Portugal
"Anticancer potential of azurin interaction with lipid rafts: deciphering the role of caveolae" (THESIS/DISSERTATION)
 19
2014/07/01 - 2014/07/31
Attended
 Laboratório de Dinâmica Cromossómica (Outros)
Instituto Gulbenkian de Ciência, Portugal
2014
Concluded
 Biology (Licenciatura)
Universidade de Lisboa Faculdade de Ciências, Portugal
"n/a" (THESIS/DISSERTATION)
 16
2011
Concluded
 Scientific-Humanities (Ensino secundário)
Escola Secundária de Gama Barros, Portugal
"n/a" (THESIS/DISSERTATION)
 16
Affiliation

Others

Category
Host institution 		Employer
2017/03/01 - 2021/09/24 PhD student in Biotechnology and Biosciences (DBiotec) Universidade de Lisboa Instituto Superior Técnico, Portugal
Universidade de Lisboa Instituto Superior Técnico, Portugal
(...)
2015/09/01 - 2016/07/01 Internship to develope the Master thesis during one academic year Universidade de Lisboa Instituto Superior Técnico, Portugal
Projects

Contract

Designation Funders
2018/01/01 - 2021/09/24 Cell penetrating p28 peptide-mediated delivery of nanomedicines for cancer treatment
LISBOA-01-0145-FEDER-030034
PhD Student Fellow
Universidade de Lisboa Instituto Superior Técnico, Portugal

Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Book chapter
  1. Garizo, Ana; Bernardes, Nuno; Fialho, Arsenio M.; Chakrabarty, A.M.. "The Anticancer Potential of the Bacterial Protein Azurin and Its Derived Peptide p28". In Microbial Infections and Cancer Therapy. Singapore: Pan Stanford Publishing Pte. Ltd., 2019.
    Published
Conference poster
  1. Garizo, Ana Rita; Nuno Bernardes; Cláudia Martins; Cristina C Barrias; Arsénio M Fialho; Bruno Sarmento. "P28-FUNCTIONALIZED GEFITINIB-LOADED PLGA NANOPARTICLES: DEVELOPMENT AND IN VITRO CHARACTERIZATION OF ANTI-CANCER ACTIVITY". Paper presented in CANCER BIOLOGY: FROM BASIC TO TRANSLATIONAL RESEARCH, 2020.
  2. Garizo, Ana Rita; Nuno Bernardes; Cláudia Martins; Cristina Barrias; Bruno Sarmento; Arsénio Fialho. "Azurin peptide-decorated gefitinib-loaded nanoparticles: development, characterization and in vitro evaluation of their anti-lung cancer activity". Paper presented in 1.º Workshop do iBB: “Fostering Collaborative Research”, 2019.
  3. Nuno Bernardes; Garizo, Ana Rita; Sofia Abreu; Sandra N Pinto; Bernardo Caniço; Catarina Perdigão; Filomena A Carvalho; et al. "Modulation of membrane properties and interaction with lipid rafts components GM-1 and caveolin-1 in cancer cells by azurin increases membrane fluidity and sensitivity to anti-cancer drugs". Paper presented in 3º Congresso Internacional da ASPIC, 2018.
Journal article
  1. Ana Rita Cebola Garizo; Lígia Fonseca Coelho; Sandra Pinto; Tiago P. Dias; Fábio Fernandes; Nuno Bernardes; Fialho AM. "The Azurin-Derived Peptide CT-p19LC Exhibits Membrane-Active Properties and Induces Cancer Cell Death". Biomedicines (2021): https://www.mdpi.com/2227-9059/9/9/1194.
    10.3390/biomedicines9091194
  2. Garizo, Ana Rita; Castro, Flávia; Martins, Cláudia; Almeida, Andreia; Dias, Tiago P.; Fernardes, Fábio; Barrias, Cristina C.; et al. "p28-functionalized PLGA nanoparticles loaded with gefitinib reduce tumor burden and metastases formation on lung cancer". Journal of Controlled Release 337 (2021): 329-342. http://dx.doi.org/10.1016/j.jconrel.2021.07.035.
    Published • 10.1016/j.jconrel.2021.07.035
  3. Bernardes, Nuno; Garizo, Ana Rita; Pinto, Sandra N.; Caniço, Bernardo; Perdigão, Catarina; Fernandes, Fábio; Fialho, Arsenio M.. "Azurin interaction with the lipid raft components ganglioside GM-1 and caveolin-1 increases membrane fluidity and sensitivity to anti-cancer drugs". Cell Cycle 17 13 (2018): 1649-1666. http://dx.doi.org/10.1080/15384101.2018.1489178.
    Published • 10.1080/15384101.2018.1489178
Thesis / Dissertation
  1. Garizo, Ana Rita. "The anticancer potential of the bacterial protein azurin and its derived peptides: mode of action and development of a nanosized drug delivery system for lung cancer therapy". PhD, 2021.
  2. Garizo, Ana Rita. "Anticancer potential of azurin interaction with lipid rafts: deciphering the role of caveolae". Master, 2016.
Activities

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2019/09/01 - 2020/12 Anti-lung cancer activity of azurin peptide-decorated gefitinib loaded nanoparticles
Co-supervisor of Luís Castro e Almeida
 Biotecnologia (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2019/10/29 - 2019/10/29 Fostering Collaborative Research
Workshop
 1.º Workshop do iBB (Instituto de Bioengenharia e Biociências)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2018/11/29 - 2018/11/30 The i3S annual meeting high-lighting ongoing and new projects that arise upon the interaction of the different integrative programs, Cancer, Host Interaction and Response and Neurobiology and Neurologic Disorders.
Meeting
 7th i3S Annual Meeting
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2018/05/10 - 2018/05/11 The 3rd ASPIC Congress give cancer researchers a stage where they speak to the inside and to the outside of the community, to patient’s associations and to the public, on their successes but also on the many still unsolved questions.
Congress
 3º Congresso Internacional da ASPIC
ASPIC - Associação Portuguesa de Investigação em Cancro, Portugal
Distinctions

Award

2018 The European Association for Cancer Research (EACR) Poster Prize
2016 "Academic Merit Diploma" for students who completed the 1st year of the master's degree with the best grades.
2015 "Academic Merit Diploma" for students who completed the course with the best grades.
2013 "Honorable Mention FCUL" for students who completed the 1st year of the course with the best grades.