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Biochemist with a PhD in Biochemistry, specialization in Molecular/Cell Biology, from the Faculty of Sciences and Technology, Coimbra University, Portugal, in collaboration with Lund University, Sweden. She has two postdocs: one in Microbiology and Immunology of Infection, from the Institute for Molecular and Cell Biology (IBMC), Porto, and the other in Cell Division and Molecular/Cell Biology, from the Institute for Research and Innovation in Health (i3S), University of Porto, Porto. Assistant Professor at Escola Superior de Saúde do Norte da Cruz Vermelha Portuguesa, Oliveira de Azeméis, where she was responsible for teaching Biochemistry and Microbiology for Nursing graduation students, as well as Laboratory Assistant Professor on the advanced PhD course in Cell Culture at Lund University, Sweden. Currently, she is a Junior Research Scientist at the Institute for Biomedicine (iBiMED), Aveiro University, in the fields of Biomedical and Health Sciences, subareas of Pharmacoepidemiology, Clinical Research and Public Health. Tânia Magalhães Silva has attended various training programs in Pharmaceutical Medicine and Clinical Research and has the Clinical Investigator Certification Level I (CLIC I), in compliance with the European PharmaTrain Syllabus, dedicated to medical sub-investigator and non-medical staff. She has published more than 12 papers in ISI web of knowledge in different fields of interest, including, Biochemistry, Cancer, Infection and Immunity, Immunology, Molecular and Cell Biology and Analytical Chemistry and presented more than 30 relevant oral and poster communications in both national and international conferences. She was invited to be a Discussion Leader and a Speaker, respectively in 2011 and 2015, at the most prestigious conference of her doctoral studies field of expertise (Gordon Research Conference on Polyamines), in USA. She is a member of the Portuguese Biochemistry and Immunology Societies and a reviewer in 4 International Journals. She is also a member of the editorial team of the publisher IntechOpen. During her career, she was awarded with national and international grants and prizes, she mentored, taught and supervised undergraduate and master students and has organized and managed many successful scientific events dedicated to Careers in Science, mostly for researchers and PhD students in Biomedical and Life Sciences. She was also team member of several financed research projects (FCT, Norte2020, QREN and ERC) over the last 10 years.
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Identification

Personal identification

Full name
Tania Raquel Magalhães Silva

Citation names

  • Silva, Tânia Magalhães
  • Silva, Tânia M

Author identifiers

Ciência ID
8919-2118-07EB
ORCID iD
0000-0003-2914-3120

Email addresses

  • tania.m.silva@ua.pt (Professional)

Addresses

  • Agra do Crasto - edifício 30, campus universitário de santiago, 3810-193, Aveiro, Aveiro, Portugal (Professional)

Websites

Knowledge fields

  • Natural sciences - Biological Sciences - Biochemistry
  • Natural sciences - Biological Sciences - Molecular Biology
  • Medical and Health Sciences - Medical Biotechnology - Technologies Involving the Manipulation of Cells, Tissues, Organs or the Whole Organism
  • Medical and Health Sciences - Basic Medicine - Pharmacology and pharmacy
  • Medical and Health Sciences - Basic Medicine - Immunology
  • Medical and Health Sciences - Basic Medicine - Medicinal Chemistry
  • Medical and Health Sciences - Health Sciences - Epidemiology

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2)
Italian Elementary (A2) Elementary (A2) Elementary (A2) Elementary (A2)
Education
Degree Classification
2020/03/16 - 2022
Ongoing
 Biomedical Sciences (subareas Clinical Research or Pharmacology) and Health Sciences (subareas Public Health or Epidemiology) (Outros)
Major in First Level Doctorate Position
Universidade de Aveiro Instituto de Biomedicina, Portugal

Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2020/03 - 2020/05
Concluded
 Pharmacovigilance for Health Professionals (8th Edition), Drug Safety and Pharmacoepidemiology (Postgraduate Certificate)
Universidad de Valladolid, Spain
 Very Good
2020 - 2020
Concluded
 Training Program in Pharmaceutical Medicine and Clinical Research: Data Management and Statistical Analysis of Clinical Studies (Outros)
Pharmaceutical Medicine Academy, Portugal

Ordem dos Farmaceuticos, Portugal
2020 - 2020
Concluded
 Training Program in Pharmaceutical Medicine and Clinical Research: Experimental Medicines and Clinical Trial Pharmacy (Outros)
Pharmaceutical Medicine Academy, Portugal

Ordem dos Farmaceuticos, Portugal
2015/07/01 - 2019/04/30
Concluded
 Molecular and Cell Biology (Pós-doutoramento)
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2019 - 2019
Concluded
 European Clinical Investigator Certification I (CLIC I) – Training Program in Pharmaceutical Medicine (Outros)
Universidade de Aveiro Associação para a Formação Profissional e Investigação, Portugal

Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
95%
2019 - 2019
Concluded
 ICH – Good Clinical Practice E6 (Outros)
Pharmaceutical Medicine Academy, Portugal

Ordem dos Farmaceuticos, Portugal
100%
2019 - 2019
Concluded
 Introduction to data analysis and image processing with MATLAB (Outros)
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2018 - 2018
Concluded
 Training Program in Pharmaceutical Medicine and Clinical Research – Monitoring and Coordination of Clinical Studies (Outros)
Pharmaceutical Medicine Academy, Portugal

Ordem dos Farmaceuticos, Portugal
2014/02/01 - 2015/06/30
Concluded
 Microbiology and Immunology of Infection (Pós-doutoramento)
Instituto de Biologia Molecular e Celular, Portugal
2015 - 2015
Concluded
 Flow Cytometry Course: Fundamentals and Applications (Outros)
Instituto de Biologia Molecular e Celular, Portugal
2015 - 2015
Concluded
 Fluorescence and Confocal Microscopy Course (Outros)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2009/01/02 - 2013/10/04
Concluded
 Bioquímica (Doutoramento)
Major in Specialisation in Molecular Biology
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"Polyamine-based Anticancer Strategies: The role of Modified Polyamines" (THESIS/DISSERTATION)
 Approved with distinction and honors by unanimity
2011 - 2011
Concluded
 Course in Laboratory Animal Science – Category C (Outros)
Universidade de Lisboa - Faculdade de Medicina Veterinária , Portugal

Federation of European Laboratory Animal Science Associations (FELASA), United Kingdom
2011 - 2011
Concluded
 Course on Pedagogical Skills Trainer (CCP) (Outros)
Instituto do Emprego e Formação Profissional, Portugal
2009 - 2009
Concluded
 Advanced PhD Course in Cell Culturing (Postgraduate Certificate)
Lunds Universitet, Sweden
2003/09 - 2008/07
Concluded
 Bioquímica (Licenciatura)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"Expression of Antizyme Inhibitor in Breast Cancer Cell Lines" (THESIS/DISSERTATION)
 16 (out of 20)
Affiliation

Science

Category
Host institution 		Employer
2020/03/16 - Current Contracted Researcher (Research) Universidade de Aveiro Instituto de Biomedicina, Portugal
2015/07/01 - 2019/04/30 Postdoc (Research) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2014/02/01 - 2015/06/30 Postdoc (Research) Instituto de Biologia Molecular e Celular, Portugal

Teaching in Higher Education

Category
Host institution 		Employer
2018/10 - 2019/07 Invited Assistant (Polytechnic Teacher) Escola Superior de Enfermagem da Cruz Vermelha Portuguesa de Oliveira de Azeméis, Portugal
2011/09/09 - 2011/10/26 Assistant (University Teacher) Lunds Universitet Biologiska institutionen, Sweden
2010/08/30 - 2010/10/29 Assistant (University Teacher) Lunds Universitet Biologiska institutionen, Sweden
Projects

Grant

Designation Funders
2020/11 - 2021/06 To take or not to take: Perceptions of the Portuguese Population on Covid-19 Vaccination
LL20-04
Researcher
Caixabank SA
2014/03 - 2019/10 Cytoplasmic Dynein: Mechanisms of Regulation and Novel Interactors
ERC-2013-StG-338410-DYNEINOME
Post-doc Fellow
European Research Council
2016 - 2019 NORTE-01-0145-FEDER-000029 - Advancing cancer research: from basic knowledgment to application
Norte2020CANCER 12
Post-doc Fellow
Quadro de Referência Estratégico Nacional
2013/12 - 2015/06 NORTE-07-0124-FEDER-000002-Host-Pathogen Interactions
ON2201310
Post-doc Fellow
Quadro de Referência Estratégico Nacional
2009/01/01 - 2012/06/30 Anticancer Activity of Novel Polyamine Pd(II) Complexes - A Multidisciplinary Study
PTDC/QUI/66701/2006
PhD Student Fellow
Fundação para a Ciência e a Tecnologia
Concluded
2009/01 - 2012/06 Anticancer Activity of Novel Polyamine Pd(II) Complexes - A Multidisciplinary Study
Provided by PTCRIS: 66701
 Fundação para a Ciência e a Tecnologia

Contract

Designation Funders
2018/07 - 2022/07 Development and validation of e-Health tools to support clinical decision and patient empowerment in respiratory infections: randomized controlled cluster trial
PTDC/SAU-SER/31678/2017
Researcher
Fundação para a Ciência e a Tecnologia
Outputs

Publications

Book
  1. New Insights into the Future of Pharmacoepidemiology and Drug Safety. IntechOpen. 2021.
    10.5772/intechopen.87642
Book chapter
  1. Herdeiro, Maria Teresa; Silva, Tania Magalhães; Inês Ribeiro-Vaz; Eva Rebelo Gomes; Adolfo Figueiras; Fátima Roque. "Pharmacovigilance and Public Health Safety". In New Insights into the Future of Pharmacoepidemiology and Drug Safety. Intechopen, 2021.
    Accepted
  2. Silva, Tania Magalhães; Eva Rebelo Gomes; Inês Ribeiro-Vaz; Fátima Roque; Herdeiro, Maria Teresa. "Assessment of Antibiotics-associated Adverse Drug Reactions". In New Insights into the Future of Pharmacoepidemiology and Drug Safety. Intechopen, 2021.
    Under revision
Conference abstract
  1. "Anxiolytics, antidepressants, sedatives and hypnotics prescription during the Covid-19 pandemic: the Portuguese case". Paper presented in 12th PCNE working conference Partnering for better patient outcomes: challenges and opportunities, Basel, 2021.
    Published • 10.1007/s11096-021-01269-4
  2. Estrela, Marta; Silva, Tania Magalhães; Pisco Almeida, Ana Margarida; Regueira, Carlos; Zapata-Cachafeiro, Maruxa; Figueiras, Adolfo; Fátima Roque; Herdeiro, Maria Teresa. "Avaliação do curso online eHealthResp por médicos: estudo de usabilidade". Paper presented in 4.ª Reunião Internacional da Rede Académica das Ciências da Saúde da Lusofonia, Benguela, 2021.
    Published
  3. Silva, Tania Magalhães; Estrela, Marta; Figueiras, Adolfo; Fátima Roque; Herdeiro, Maria Teresa. "A countrywide study in Portugal addressing antibiotic prescription during the Covid-19 pandemic". Paper presented in Trabalho apresentado em 12th PCNE Working Conference 2021, Online Partnering for better patient outcomes- challenges and opportunities, 2021.
    Published
  4. Maria V Cade; Silva, Tania Magalhães; Adolfo Figueiras; Fátima Roque; Delanjathan Devakumar; Maria Teresa Herdeiro. "Xenophobia during COVID-19 epidemic: an overview". Paper presented in I CONGRESO VIRTUAL DE LA SOCIEDAD ESPAÑOLA DE EPIDEMIOLOGÍA (SEE) Y DA ASSOCIAÇÃO PORTUGUESA DE EPIDEMIOLOGIA (APE), 2020.
    Published
  5. Carina Brito; Silva, Tania Magalhães; Ana Gonçalves; Natércia Teixeira; Margarida Borges. "Determination of macrophage activation profile during Toxoplasma gondii infection and implications on pregnancy outcome using the mice model". Porto, 2015.
    Published
Conference paper
  1. Marcos Cardoso; Silva, Tania Magalhães; Rui Appelberg; Margarida Borges. "Transcription factor hypoxia-inducible factor (HIF)- 1alpha is relevant for necrosis of Mycobacterium avium-induced granulomas". Paper presented in FEBS EMBO 2014 Conference, Paris, 2014.
    Published • 10.1111/febs.12914
  2. Silva, Tania Magalhães; Maria Paula Marques; Patrick Woster; Lo Persson; Stina Oredsson. "Antiproliferative activity of novel Pd(II) and Pt(II) polyamine analogue complexes in human breast cancer cell lines". Paper presented in FEBS EMBO 2013, São Petersburgo, 2013.
    Published • 10.1111/febs.12339
  3. Silva, Tania Magalhães. "DNA Toxicity of Pt(ll) and Pd(ll) Polyamine Complexes in Human Breast Cancer Cells". 2011.
    10.1016/S0959-8049(11)71534-9
Journal article
  1. Marta Estrela; Catarina Leitão; Tânia Magalhães Silva; Adolfo Figueiras; Fátima Roque; Maria Teresa Herdeiro. "Insights on COVID-19 Vaccination in Portugal: A Qualitative Study among Health Professionals and Teachers". Vaccines (2022): https://doi.org/10.3390/vaccines10121984.
    10.3390/vaccines10121984
  2. Tânia Magalhães Silva; Marta Estrela; Sandra Magalhães; Catarina Simões; Afonso Cachim; Tainá Costa; Gabriella Crexinski; et al. "eHealthResp, a Digital Intervention to Improve Antibiotic Prescribing in Respiratory Infections: A Pilot Study". Life (2022): https://doi.org/10.3390/life12081160.
    10.3390/life12081160
  3. Sandra Magalhães; Marta Estrela; Tânia Magalhães Silva; Tainá Costa; Gabriella Crexinski; Catarina Simões; Margarida Pisco Almeida; et al. "Improving Pharmacists’ Awareness of Inadequate Antibiotic Use for URTIs through an Educational Intervention: A Pilot Study". Healthcare (2022): https://doi.org/10.3390/healthcare10081385.
    10.3390/healthcare10081385
  4. Marta Estrela; Tânia Magalhães Silva; Vítor Roque; Eva Rebelo Gomes; Fátima Roque; Maria Teresa Herdeiro; Adolfo Figueiras. "What determines health professionals’ COVID-19 vaccine hesitancy? A nationwide study". European Journal of Clinical Investigation (2022): https://doi.org/10.1111/eci.13785.
    10.1111/eci.13785
  5. "Impact of infectious disease epidemics on xenophobia: a systematic review". Journal of Migration and Health (2022): 100085-100085. http://dx.doi.org/10.1016/j.jmh.2022.100085.
    10.1016/j.jmh.2022.100085
  6. Silva, Tania Magalhães; Estrela, Marta; Rebelo Gomes, Eva; Roque, Vitor; Figueiras, Adolfo; Roque, Maria de Fátima dos Santos Marques; Herdeiro, Maria Teresa. "Perceptions, knowledge, and attitudes about COVID-19 vaccine hesitancy in older Portuguese adults". Age and Ageing (2022):
    Accepted
  7. "A roadmap for the development and evaluation of the eHealthResp online course". DIGITAL HEALTH 8 (2022): 205520762210890-205520762210890. http://dx.doi.org/10.1177/20552076221089088.
    10.1177/20552076221089088
  8. Marta Estrela; Tânia Magalhães Silva; Eva Rebelo Gomes; Maria Piñeiro; Adolfo Figueiras; Fátima Roque; Maria Teresa Herdeiro. "Prescription of anxiolytics, sedatives, hypnotics and antidepressants in outpatient, universal care during the COVID-19 pandemic in Portugal: a nationwide, interrupted time-series approach". Journal of Epidemiology and Community Health (2021): jech--2021--216732-jech--2021--216732. https://doi.org/10.1136/jech-2021-216732.
    10.1136/jech-2021-216732
  9. Tânia Magalhães Silva; Marta Estrela; Eva Rebelo Gomes; Maria Piñeiro-Lamas; Adolfo Figueiras; Fátima Roque; Maria Teresa Herdeiro. "The Impact of the COVID-19 Pandemic on Antibiotic Prescribing Trends in Outpatient Care: A Nationwide, Quasi-Experimental Approach". Antibiotics 10 9 (2021): 1040-1040. https://doi.org/10.3390/antibiotics10091040.
    10.3390/antibiotics10091040
  10. "Validation of the eHealthResp online course for pharmacists and physicians: A Delphi method approach". Biomedicine & Pharmacotherapy 140 (2021): 111739-111739. http://dx.doi.org/10.1016/j.biopha.2021.111739.
    10.1016/j.biopha.2021.111739
  11. Brito, Carina; M. Silva, Tânia; M. Castro, Maria; Wyrwas, Weronika; Oliveira, Bárbara; M. Fonseca, Bruno; Oliveira, Pedro; et al. "Toxoplasma gondii infection reduces serum progesterone levels and adverse effects at the maternal-foetal interface". Parasite Immunology 42 2 (2019): http://dx.doi.org/10.1111/pim.12690.
    10.1111/pim.12690
  12. Borges, Margarida; Magalhães Silva, Tânia; Brito, Carina; Teixeira, Natércia; Roberts, Craig W.. "How does toxoplasmosis affect the maternal-foetal immune interface and pregnancy?". Parasite Immunology 41 3 (2018): e12606. http://dx.doi.org/10.1111/pim.12606.
    10.1111/pim.12606
  13. Silva, T.M.; Fiuza, S.M.; Marques, M.P.M.; Batista De Carvalho, L.A.E.; Amado, A.M.. "Conformational study and reassessment of the vibrational assignments for Norspermidine". Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy 157 (2016): 227-237. http://www.scopus.com/inward/record.url?eid=2-s2.0-84954554378&partnerID=MN8TOARS.
    10.1016/j.saa.2016.01.003
  14. Cardoso MS; Silva TM; Resende M; Appelberg R; Borges M. "Lack of the Transcription Factor Hypoxia-Inducible Factor 1a (HIF-1a) in Macrophages Accelerates the Necrosis of Mycobacterium avium-Induced Granulomas.". (2015): http://europepmc.org/abstract/med/26099585.
    10.1128/IAI.00144-15
  15. Silva, Tania M.; Cirenajwis, Helena; Wallace, Heather M.; Oredsson, Stina; Persson, Lo. "A role for antizyme inhibitor in cell proliferation". Amino Acids 47 7 (2015): 1341-1352. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000355745900005&KeyUID=WOS:000355745900005.
    10.1007/s00726-015-1957-6
  16. Fiuza, S.M.; Silva, T.M.; Marques, M.P.M.; de Carvalho, L.A.E.B.; Amado, A.M.. "On the correction of calculated vibrational frequencies for the effects of the counterions — a,¿-diamine dihydrochlorides". Journal of Molecular Modeling 21 10 (2015): http://www.scopus.com/inward/record.url?eid=2-s2.0-84942425899&partnerID=MN8TOARS.
    10.1007/s00894-015-2818-7
  17. Silva, T.M.; Fiuza, S.M.; Marques, M.P.M.; Persson, L.; Oredsson, S.. "Increased breast cancer cell toxicity by palladination of the polyamine analogue N1,N11-bis(ethyl)norspermine". Amino Acids 46 2 (2014): 339-352. http://www.scopus.com/inward/record.url?eid=2-s2.0-84895910981&partnerID=MN8TOARS.
    10.1007/s00726-013-1621-y
  18. Silva, T.M.; Andersson, S.; Sukumaran, S.K.; Marques, M.P.; Persson, L.; Oredsson, S.. "Norspermidine and Novel Pd(II) and Pt(II) Polynuclear Complexes of Norspermidine as Potential Antineoplastic Agents Against Breast Cancer". PLoS ONE 8 2 (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84873905382&partnerID=MN8TOARS.
    10.1371/journal.pone.0055651
  19. Silva, T.M.; Oredsson, S.; Persson, L.; Woster, P.; Marques, M.P.M.. "Novel Pt(II) and Pd(II) complexes with polyamine analogues: Synthesis and vibrational analysis". Journal of Inorganic Biochemistry 108 (2012): 1-7. http://www.scopus.com/inward/record.url?eid=2-s2.0-84855870600&partnerID=MN8TOARS.
    10.1016/j.jinorgbio.2011.11.021
  20. Duarte, I.F.; Marques, J.; Ladeirinha, A.F.; Rocha, C.; Lamego, I.; Calheiros, R.; Silva, T.M.; et al. "Analytical approaches toward successful human cell metabolome studies by NMR spectroscopy". Analytical Chemistry 81 12 (2009): 5023-5032. http://www.scopus.com/inward/record.url?eid=2-s2.0-67249083144&partnerID=MN8TOARS.
    10.1021/ac900545q
Thesis / Dissertation
  1. Silva, Tania Magalhães. "Polyamine-based anticancer strategies: the role of modified polyamines". PhD, Universidade de Coimbra Faculdade de Ciencias e Tecnologia, 2013.
  2. Silva, Tânia Raquel de Magalhães e. "Polyamine-based anticancer strategies: the role of modified polyamines". PhD, 2013. http://hdl.handle.net/10316/31520.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2021/12 Validação da aplicação eHealthResp através do Método Delphi. VI Jornadas de Educação e Investigação em Saúde
(Guarda, Portugal)
2021/11 Avaliação do curso online eHealthResp por médicos: estudo de usabilidade 4ª Reunião Rede Académica Ciencias Saúde Lusofonia
(Benguela, Angola)
2021/10 Vacinação contra a Covid-19 em Portugal: Qual a perceção e adesão dos profissionais de saúde? 42ª Reunião Anual da Sociedade Portuguesa de Alergologia e Imunologia Clínica, SPAIC 2021, Desafios e Oportunidades
(Portugal)
2021/04 Vacinação contra a COVID-19 em Portugal: Quais as perceções da população? XII Biochemistry Day | The Biochemistry of SARS-CoV-2
University of Aveiro (Portugal)
2021 Highlights of the antibiotic prescription tendencies in Portugal during the Covid-19 pandemic: a nationwide, quasi-experimental study LI Meeting of the Portuguese Society of Pharmacology, XXXIX Meeting of Clinical Pharmacology and XX Meeting of Toxicology
(Portugal)
2021 Highlights of the anxiolytics, sedatives, hypnotics, and antidepressants prescription tendencies in Portugal during the COVID-19 pandemic: a nationwide, quasi-experimental study LI Meeting of the Portuguese Society of Pharmacology, XXXIX Meeting of Clinical Pharmacology and XX Meeting of Toxicology
(Portugal)
2021 Anxiolytics, antidepressants, sedatives and hypnotics prescription during the Covid-19 pandemic: the Portuguese case 12th PCNE Working Conference 2021
2020/10 Xenophobia during covid-19 epidemic: An overview I Congreso Virtual de la Sociedad Española de Epidemiología (SEE) y da Associação Portuguesa de Epidemiologia (APE).
2019 Toxoplasmosis during pregnancy: clinical outcomes and effects on the maternal-foetal interface IV International Conference of Health Research – Responding to the changing world
(Oliveira de Azeméis, Portugal)
2015 Polyamine-based Anticancer Strategies – the role of modified polyamines Gordon Research Conference on Polyamines
(Waterville Valley, United States)
2014 Determination of hypoxia-inducible factor (HIF)-1a relevance in the immunopathology associated with Mycobacterium avium infection ON.2 Symposium on Host-Pathogen Interactions
(Porto, Portugal)
2012 Cytotoxicity of Pd(II)-DENSpm and Pt(II)-CPENSpm in Human Breast Cancer Cell Lines Polyamines: Biological and Clinical Perspectives
(Istanbul, Turkey)
2012 Pd(II) and Pt(II) Polyamine Complexes As Potential Anticancer Agents: Cytotoxic Activity Towards Human Breast Cancer International Symposium on Platinum Coordination Compounds in Cancer Chemotherapy
(Verona, Italy)
2010 Vibrational and Cytotoxic Studies on a Modified Spermidine and its Pd(II) Complex 2010 International Polyamine Conference
(Gotemba, Japan)
2010 Pd(II) and Pt(II) Polyamine Analogue Complexes as Potential Anticancer Agents 2nd International Conference on the role of Polyamines and their Analogues in Cancer and other Diseases
(Rome, Italy)
2009 Vibrational Studies on Modified Polyamines Polyamines Gordon Research Conference and Seminar
(Waterville Valley, United States)
2008/12 The Role of Antizyme Inhibitor in Human Cancer Cell Lines XXXIX Annual Reunion of the Portuguese Pharmacology Society – XXVI Clinical Pharmacology Reunion, VII Toxicology Reunion
(Lisbon, Portugal)

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2018 - 2018 Member of the organizing committee of the workshop entitled "Moving from Academia to Industry", promoted by the i3S Postdoc Association, dedicated to career development and job transitions, mostly for researchers and PhD students in Biomedical and Life Sciences. (2018)
Workshop (Co-organisor)
 Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2018 - 2018 Member of the organizing committee of the workshop entitled "Career Development for researchers in Biosciences", promoted by the i3S Postdoc Association, dedicated to career development, job transitions, CV writing, mostly for researchers and PhD students in Biomedical and Life Sciences (2018)
Workshop (Member of the Organising Committee)
 Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2017 - 2017 Member of the organizing committee of the workshop entitled "Writing your way into the right job: a CV skills workshop", promoted by the i3S Postdoc Association, dedicated to CV writing mostly for researchers and PhD students in Biomedical and Life Sciences. (2017)
Workshop (Member of the Organising Committee)
 Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2017 - 2017 Member of the organizing committee of the workshop entitled "Career Development Opportunities: Group training on effective communication and 1-on-1 career guidance", promoted by the i3S Postdoc Association, dedicated to career development and job transitions, mostly for researchers and PhD students in Biomedical and Life Sciences. (2017)
Workshop (Member of the Organising Committee)
2016 - 2016 Member of the organizing committee of the workshop entitled "Careers in Science: Life after a PhD", promoted by the i3S Postdoc Association, dedicated to career development mostly for researchers and PhD students in Biomedical and Life Sciences. (2016 - 2016)
Workshop (Member of the Organising Committee)
 Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2021/10 - Current Poster Communication: E. Gomes, T. M. Silva, M. Estrela, V. Roque, A. Figueiras, F. Roque, M. T. Herdeiro, "Vacinação contra a Covid-19 em Portugal: Qual a perceção e adesão dos profissionais de saúde?", 42ª Reunião Anual da Sociedade Portuguesa de Alergologia e Imunologia Clínica, SPAIC 2021, Desafios e Oportunidades, October, 7th to 9th 2021, Reunião Online.
Other
 Reunião Anual da Sociedade Portuguesa de Alergologia e Imunologia Clínica, SPAIC 2021, Desafios e Oportunidades
2021 - Current Poster Communication: T. M. Silva, M. Estrela, A. Figueiras, F. Roque, M. T. Herdeiro, "A countrywide study in Portugal addressing antibiotic prescription during the Covid-19 pandemic", 12th PCNE Working Conference 2021, February 3rd – 6th 2021, Basel, Switzerland.
Conference
 12th PCNE Working Conference 2021
2021 - Current Poster Communication: M. Estrela, T. M. Silva, A. Figueiras, F. Roque, M. T. Herdeiro, "Anxiolytics, antidepressants, sedatives and hypnotics prescription during the Covid-19 pandemic: the Portuguese case", 12th PCNE Working Conference 2021, Basel, Switzerland.
Conference
 12th PCNE Working Conference 2021
2018 - Current Poster Communication: M. Borges, C. Brito, M. M. Castro, T. M Silva, C. Roberts, N. Teixeira, "Pregnancy down-regulates MHCII expression by microphages during Toxoplasma gondii infection", Toll 2018 Editing Innate Immunity, June 6th ¿ 9th 2018, Porto, Portugal.
Meeting
 Toll 2018 Editing Innate Immunity
2018 - Current Poster Communication: T. M. Silva, P. A. Simões, R. Gassmann, "Dissecting dynactin's role in bipolar spindle assembly in somatic cells of the C. elegans early embryo", EMBO workshop: C. elegans Development, Cell Biology and Gene Expression, June 13th ¿ 17th 2018, Barcelona, Spain.
Workshop
 EMBO workshop: C. elegans Development, Cell Biology and Gene Expression
2016 - Current Poster Communication: D. Barbosa, T. M. Silva, J. Fernandes, P. A. Simões, R. Gassmann, "Dissecting the mitotic functions of dynactin in the early C. elegans embryo", EMBO/EMBL Symposia: Microtubules - From atoms to complex systems, May 29th ¿ June 1st 2016, EMBL Heidelberg, Germany.
Symposium
 EMBO/EMBL Symposia: Microtubules – From atoms to complex systems
2015 - Current Poster Communication: C. Brito, A. Gonçalves, T. M. Silva, N. Teixeira, M. Borges, “Arginase 1 and iNOS expression at the fetomaternal interface during Toxoplasma gondii infection”, Ijup’15, May 14th – 16th 2015, Porto, Portugal.
Other
 IJUP 2015
2015 - Current Poster Communication: C. Brito, T. M. Silva, N. Teixeira, M. Borges, “Arginase 1 and iNOS expression at systemic level and fetomaternal interface during Toxoplasma gondii infection”, YES Meeting, September 15th – 18th 2015, Faculty of Medicine of the University of Porto, Porto, Portugal.
Meeting
 YES Meeting
2015 - Current Poster Communication: C. Brito, A. Gonçalves, T. M. Silva, N. Teixeira, M. Borges, “Determination of macrophage activation profile during Toxoplasma gondii infection and implications on pregnancy outcome using the mice model”, UMIB, September, 24th – 25th 2015, ICBAS-FFUP, Porto, Portugal.
Other
 UMIB Summit 2015
2014 - Current Poster Communication: M. S. Cardoso, T. M. Silva, R. Appelberg, M. Borges, "Transcription factor hypoxia-inducible factor (HIF)-1a is relevant for necrosis of Mycobacterium avium-induced granulomas", Federation of European Biochemical Societies (FEBS) Congress 2014, August 30th – September 4th 2014, Paris, France.
Congress
 Federation of European Biochemical Societies (FEBS) Congress 2014
2014 - Current Poster Communication: T. M. Silva, S. Loureiro, A. Gonçalves, R. Appelberg, C. W. Roberts, N. Teixeira, M. Borges, "Determination of the macrophage profile and distribution during Toxoplasma gondii infection and pregnancy", 40th Annual Meeting of the Portuguese Society for Immunology – From Immune Responses to Immunotherapy, October 13th – 15th 2014, Lisbon, Portugal.
Meeting
 40th Annual Meeting of the Portuguese Society for Immunology – From Immune Responses to Immunotherapy
2014 - Current Poster Communication: M. S. Cardoso, T. M. Silva, M. Resende, R. Appelberg, M. Borges, "Lack of the transcription factor hypoxia-inducible factor (HIF)-1a accelerates the necrosis of Mycobacterium avium-induced granulomas", 40th Annual Meeting of the Portuguese Society for Immunology – From Immune Responses to Immunotherapy, October 13th – 15th 2014, Lisbon, Portugal.
Meeting
 40th Annual Meeting of the Portuguese Society for Immunology – From Immune Responses to Immunotherapy
2013 - Current Poster Communication: T. M. Silva, M. P. M. Marques, L. Persson, S. Ordesson, "Antiproliferative Activity of Novel Pd(II) and Pt(II)-Polyamine Analogue Complexes in Human Breast Cancer Cell Lines", Federation of European Biochemical Societies (FEBS) Congress 2013: “Mechanisms in Biology”, July 7th – 11th 2013, St. Petersburg, Russia.
Congress
 Federation of European Biochemical Societies (FEBS) Congress 2013: “Mechanisms in Biology”
2013 - Current Participation as an attendee on the 7th National Meeting on Cell Signalling, December 6th – 7th 2013, at the University of Aveiro, Aveiro, Portugal.
Meeting
 7th National Meeting on Cell Signalling
2012 - Current Poster Communication: T. M. Silva, M. P. M. Marques, P. M. Woster, L. Persson, S. Ordesson, "Cytotoxicity of Pd(II)-DENSpm and Pt(II)-CPENSpm in Human Breast Cancer Cell Lines", Polyamines: Biological and Clinical Perspectives, September 2nd – 7th 2012, Istanbul, Turkey.
Conference
 Polyamines: Biological and Clinical Perspectives
2012 - Current Participation as an attendee in the workshop “Alternatives to Animal Use in Pre-Clinical Studies”, December 10th 2012, at Biocant, Cantanhede, Portugal.
Workshop
 Alternatives to Animal Use in Pre-Clinical Studies
2011 - Current Poster Communication: T. M. Silva, S. Oredsson, L. Persson, M. P. M. Marques,“Polyamine Analogues and their Pd(II) Complexes: Synthesis and Conformational Analysis”, Polyamines Gordon Research Conference and Seminar, June 18t – 24th 2011, Waterville Valley, NH, USA.
Seminar
 Polyamines Gordon Research Conference and Seminar
2011 - Current Poster Communication: T. M. Silva, N. F. L. Machado, S. Oredsson, L. Persson, P. M. Woster, M. P. M. Marques, “Modified Biogenic Polyamines and their Pt(II) Complexes as Promising New Anticancer Agents: a Vibrational Spectroscopy Study”, 14th European Conference on the Spectroscopy of Biological Molecules, August 29th – September 3rd 2011, Coimbra, Portugal.
Conference
 14th European Conference on the Spectroscopy of Biological Molecules
2011 - Current Poster Communication: T. M. Silva, M. P. M. Marques, L. Persson, S. Oredsson,“DNA Toxicity of Pt(II) and Pd(II) Polyamine Complexes in Human Breast Cancer Cells”, The European Multidisciplinary Cancer Congress, September 23rd – 27th 2011, Stockholm, Sweden.
Congress
 The European Multidisciplinary Cancer Congress
2010 - Current Poster Communication: T. M. Silva, S. Oredsson, L. Persson, M. P. M. Marques,”Vibrational and Cytotoxic Studies on a Modified Spermidine and its Pd(II) Complex”, International Polyamine Conference, June 14th – 18th 2010, Gotemba, Japan.
Conference
 International Polyamine Conference
2010 - Current Poster Communication: T. M. Silva, S. Oredsson, L. Persson, L. A. E. Batista de Carvalho, M. P. M. Marques, "Modified Polyamines as Potential Anticancer Tools: a Vibrational Spectroscopy Study", VI Spectrocopy Iberic Congress, XXIII National Reunion of Spectroscopy, September 8th - 10th 2010, Porto, Portugal.
Congress
 VI Spectrocopy Iberic Congress – XXIII National Reunion of Spectroscopy
2010 - Current Poster Communication: T. M. Silva, H. Cirenajwis, S. Andersson, M. P. M. Marques, L. Persson, S. Oredsson, ”Pd(II) and Pt(II) Polyamine Analogue Complexes as Potential Anticancer Agents”, 2nd International Conference on the role of Polyamines and their Analogues in Cancer and other Diseases, December 1st – 6th 2010, Rome, Italy.
Conference
 2nd International Conference on the role of Polyamines and their Analogues in Cancer and other Diseases
2009 - Current Poster Communication: J. Marques, A. F. Ladeirinha, T. M. Silva, R. Calheiros, M. P. M. Marques, I. Carreira, J. Melo, I.F. Duarte & A. M. Gil, “Establishing the Conditions for NMR-based Cell Metabonomics”, VI CICECO Journeys, March 5th – 6th 2009, Aveiro, Portugal.
Other
 VI CICECO Journeys
2009 - Current Poster Communication: T. M. Silva, S. Oredsson, L. Persson, M. P. M. Marques, ”Vibrational Studies on Modified Polyamines”, Polyamines Gordon Research Conference and Seminar, June 20th – 26th 2009, Waterville Valley, NH, USA.
Seminar
 Polyamines Gordon Research Conference and Seminar
2008 - Current Poster Communication: T. M. Silva, E. Söderstjerna, C. Freiburghaus, H. Cirenajwis, K. Alm, S. Oredsson & L. Persson, ”Expression of Antizyme Inhibitor in Breast Cancer Cell Lines”, Polyamines: Forty years of Mammalian Ornithine Decarboxylase – International Congress of Polyamines, June 26th – 30th 2008, Kuopio, Finland
Congress
 Polyamines: Forty years of Mammalian Ornithine Decarboxylase – International Congress of Polyamines
2006 - Current Participation as an attendee in the XV National Congress of Biochemistry, December 8th – 10th 2006, at the University of Aveiro, Aveiro, Portugal.
Congress
 XV National Congress of Biochemistry
2005 - Current Participation as an attendee on the 2nd National Meeting of Biochemistry Students at the Faculty of Sciences of the University of Lisbon, April 23rd - 25th 2005, in Lisbon, Portugal.
Meeting
 2nd National Meeting of Biochemistry Students
2005 - Current Participation as an attendee in the 1st National Congress of Virology – 5th National Meeting of Portuguese Society Virology, November 14th – 15th 2005, in Coimbra, Portugal.
Meeting
 5th National Meeting of Portuguese Society Virology

Association member

Society Organization name Role
2014 - Current Portuguese Immunology Society
2010 - Current Portuguese Biochemistry Society

Committee member

Activity description
Role 		Institution / Organization
2015 - 2018 I3S Postdoc Association (iPDA) Committee Member. This association was responsible for the organization of several meetings and workshops dedicated to career development, job transitions and CV writing, especially for researchers and PhD students in Biomedical and Life Sciences.
Member
 Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2011/04 - Current Assistant researcher during the practical classes of a 4–week course from the Master Degree in Biochemistry, University of Coimbra, Coimbra, Portugal. Bioquímica (Mestrado) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2018/10 - 2019/07 Head Professor of Biochemistry and Microbiology - 1st year of Nursing graduation. Biochemistry and Microbiology (Licenciatura) Escola Superior de Enfermagem da Cruz Vermelha Portuguesa de Oliveira de Azeméis, Portugal
2011/09/09 - 2011/10/26 Lab assistant on the advanced PhD course in Cell Culturing (total of 95 h), at the University of Lund, Lund, Sweden. (Doktor (PhD)) Lunds Universitet Biologiska institutionen, Sweden
2010/08/10 - 2010/10/29 Lab assistant on the advanced PhD course in Cell Culturing (total of 105 h), at the University of Lund, Lund, Sweden. (Doktor (PhD)) Lunds Universitet Biologiska institutionen, Sweden

Journal scientific committee

Journal title (ISSN) Publisher
2014 - Current Amino Acids Journal Springer

Mentoring / Tutoring

Topic Student name
2014 - 2014 Mentor of a Master student in Pharmaceutical Sciences Carina Leiria

Other jury / evaluation

Activity description Institution / Organization
2016 - 2016 External PhD Reviewer of the thesis "Investigating the oxidative/nitrosative stress response induced by HIV-TAT protein in glial and neuronal cell", presented by the PhD student Roberta Mastrantonio. Università degli Studi Roma Tre, Italy
Distinctions

Award

2021 Best Oral Communication Award at SPAIC's 42nd annual meeting
Sociedade Portuguesa de Alergologia e Imunologia Clínica, Portugal
2010 Best Poster Award at International Polyamine Conference
International Polyamine Conference 2010 Organizing Committee, Japan

Other distinction

2013 FEBS Congress 2013: Mechanisms in Biology - FEBS bursary
Federation of European Biochemical Societies, United Kingdom
2012 Young Investigator Grant for the Polyamine International Conference: Biological and Clinical Perspectives
Kungliga Fysiografiska Sällskapet I Lund, Sweden
2008 PhD fellowship (SFRH/BD/46364/2008)
Fundação para a Ciência e a Tecnologia, Portugal