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Mélanie Audrey Gomes Barbosa holds a BSc degree in Biology from the Faculty of Sciences of the University of Porto (2015). In 2017, she completed her MSc degree in Toxicology and Environmental Contamination at the Institute of Biomedical Sciences of Abel Salazar, after presenting her dissertation titled "Obesity and environmental pollutants: a reason for concern?" that was carried out in the Endocrine Disruptors and Emergent Contaminants (EDEC) group of the Interdisciplinary Centre of Marine and Environmental Research (CIIMAR), under the supervision of Dr. Miguel Santos. Her stay at CIIMAR has allowed her to publish her first two papers in Q1 peer-reviewed journals in that area, one of them as the first author which was awarded by the 2019 IACOBUS Program - Scientific publications. From June 2020 to October 2021, she worked on her Master Research Fellowship (LOOKER_2_BI_M) for the project "Biomarkers for minimal residual disease" at the Cancer Drug Resistance group of the Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP/I3S). In 2020, she was awarded a PhD scholarship, by the Fundação para a Ciência e a Tecnologia (FCT), to work on the thesis titled "Modern 3D drug screening methodologies for the identification of novel antitumor drugs capable of counteracting multidrug resistance in cancer", inserted in the PhD program in Pharmaceutical Sciences at the Faculty of Pharmacy of the University of Porto. Recently, she published a review paper, in the topic of her thesis, in the Q1 peer-reviewed journal Cancers, titled "3D cell culture models as recapitulators of the tumor microenvironment for the screening of anti-cancer drugs".
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Identification

Personal identification

Full name
Mélanie Audrey Gomes Barbosa
Date of birth
1993/03/04
Gender
Female

Citation names

  • Barbosa, Mélanie A. G.

Author identifiers

Ciência ID
8B1B-D488-E7E5
ORCID iD
0000-0002-7354-4338

Email addresses

  • melanieb@ipatimup.pt (Professional)
  • melanie_barbosa@hotmail.com (Personal)

Telephones

Mobile phone
  • 916911562 (Personal)

Addresses

  • Rua Virgílio Ferreira, nº 82, 3º Esquerdo, 4430-686, Vila Nova de Gaia, Vila Nova de Gaia, Portugal (Personal)

Knowledge fields

  • Natural sciences - Biological Sciences - Cell Biology
  • Natural sciences - Biological Sciences - Molecular Biology
  • Medical and Health Sciences - Health Sciences - Public and Environmental Health
  • Medical and Health Sciences - Basic Medicine - Toxicology
  • Medical and Health Sciences - Clinical Medicine - Endocrinology and Metabolism
  • Medical and Health Sciences - Clinical Medicine - Oncology

Languages

Language Speaking Reading Writing Listening Peer-review
French (Mother tongue)
Portuguese Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2)
English Advanced (C1) Proficiency (C2) Advanced (C1) Proficiency (C2) Advanced (C1)
Education
Degree Classification
2020/11/01 - 2024/11/01
Ongoing
 Ciências Farmacêuticas (Doutoramento)
Major in Biologia Celular e Molecular
Universidade do Porto Faculdade de Farmácia, Portugal
2021/10/29 - 2022
Ongoing
 Introductory Laboratory Animal Science Course [functions A + D] (Outros)
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2015/10/08 - 2017/11/22
Concluded
 Toxicologia e Contaminação Ambientais (Mestrado)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
"Obesity and environmental pollutants: a reason for concern?" (THESIS/DISSERTATION)
 18
2011/09 - 2015/09
Concluded
 Biologia (Licenciatura)
Universidade do Porto Faculdade de Ciências, Portugal
"Aerobiology of Pinus spp and effects of different O3 levels on pollen fertility, proteins and allergenicity." (THESIS/DISSERTATION)
 14
Affiliation

Science

Category
Host institution 		Employer
2019/06/11 - 2020/10/31 Researcher (Research) Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
(...)
2018/03/01 - 2018/06/30 Researcher (Research) Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
2016/08/01 - 2017/11/23 Research Trainee (Research) Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
2014/07 - 2015/09 Research Trainee (Research) Universidade do Porto Faculdade de Ciências, Portugal
Universidade do Porto Faculdade de Ciências, Portugal
Projects

Grant

Designation Funders
2020/11/01 - Current Modern 3D drug screening methodologies for the identification of novel antitumor drugs capable of counteracting multidrug resistance in cancer
2020.08712.BD
PhD Student Fellow
Fundação para a Ciência e a Tecnologia
Ongoing
2019/06/11 - 2020/06/11 LOOKER Project: Biomarkers for minimal residual disease
LOOKER_2_BI_M
Master Student Fellow
Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal

Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Universidade do Porto Instituto de Patologia e Imunologia Molecular
Ongoing
Outputs

Publications

Conference poster
  1. Barbosa, Mélanie A. G.. "Aerobiology of Pinus spp and effects of different O 3 levels on pollen fertility, proteins and allergenicity". Paper presented in IJUP’ 15 8 º Encontro de Jovens Investigadores da Universidade do Porto), 2015.
Journal article
  1. Rui Bergantim; Sara Peixoto da Silva; Bárbara Polónia; Barbosa, Mélanie A. G.; André Albergaria; Jorge Lima; Hugo R. Caires; José E. Guimarães; M. Helena Vasconcelos. "Detection of Measurable Residual Disease Biomarkers in Extracellular Vesicles from Liquid Biopsies of Multiple Myeloma Patients: A Proof of Concept". International Journal of Molecular Sciences (2022): https://www.mdpi.com/1422-0067/23/22/13686.
    10.3390/ijms232213686
  2. Mélanie Barbosa; Xavier CP; Pereira R.F.; Vilma Petrikaite; M. Helena Vasconcelos. "3D Cell Culture Models as Recapitulators of the Tumor Microenvironment for the Screening of Anti-Cancer Drugs". Cancers (2021): https://www.mdpi.com/2072-6694/14/1/190.
    10.3390/cancers14010190
  3. Xavier, Cristina P. R.; Caires, Hugo R.; Barbosa, Mélanie A. G.; Bergantim, Rui; Guimarães, José E.; Vasconcelos, M. Helena. "The Role of Extracellular Vesicles in the Hallmarks of Cancer and Drug Resistance". Cells 9 5 (2020): 1141. http://dx.doi.org/10.3390/cells9051141.
    Published • 10.3390/cells9051141
  4. Barbosa, Mélanie Audrey Gomes; Capela, Ricardo; Rodolfo, Jorge; Fonseca, Elza; Montes, Rosa; André, Ana; Capitão, Ana; et al. "Linking chemical exposure to lipid homeostasis: A municipal waste water treatment plant influent is obesogenic for zebrafish larvae". Ecotoxicology and Environmental Safety 182 (2019): 109406. http://dx.doi.org/10.1016/j.ecoenv.2019.109406.
    Published • 10.1016/j.ecoenv.2019.109406
  5. Capitão, Ana M. F.; Lopes-Marques, Mónica S.; Ishii, Yoichiro; Ruivo, Raquel; Fonseca, Elza S. S.; Páscoa, Inês; Jorge, Rodolfo P.; et al. "Evolutionary Exploitation of Vertebrate Peroxisome Proliferator-Activated Receptor gamma by Organotins". Environmental Science & Technology 52 23 (2018): 13951-13959. http://dx.doi.org/10.1021/acs.est.8b04399.
    Published • 10.1021/acs.est.8b04399
Thesis / Dissertation
  1. Barbosa, Mélanie A. G.. "Obesity and environmental pollutants: a reason for concern?". Master, Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, 2017. https://sigarra.up.pt/icbas/pt/pub_geral.show_file?pi_doc_id=126169.
Activities

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2020/02/12 - 2020/02/14 Presença no evento e co-autora da Apresentação: "Implementing and validating an Extracellular Vesicle isolation protocol for the detection of clinically established leukaemia associated immunophenotypic markers in the blood plasma of Acute Myeloid Leukaemia patients"
Meeting
 IJUP'20 - 13º Encontro de Jovens Investigadores da Universidade do Porto
Universidade do Porto, Portugal
2019/11/06 - 2019/11/06 Presença no simpósio
Symposium
 6th edition | MCBiology Symposium: From InCell to ExCell
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2017/10/18 - 2017/10/18 Presença na conferência
Conference
 9 º Simpósio de Metabolismo Metabolic syndrome focus on cardiovascular disease and cancer
Universidade do Porto Faculdade de Medicina, Portugal
2015/09/23 - 2015/09/23 Presença na conferência
Conference
 INAIRCHILD Poluição do Ar Interior em Infantários e Escolas Primárias Impacte na asma infantil
Universidade do Porto Faculdade de Engenharia, Portugal
2012/05/23 - 2012/05/23 Presença na conferência
Conference
 Novas Abordagens para Engenharia de Tecidos Humanos
Universidade Católica Portuguesa Centro Regional do Porto, Portugal

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2022/03/07 - 2022/03/10 Course in Introductory Statistics for Biological Sciences (Outros) Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
2022/02/21 - 2022/02/23 Workshop on SeaHorse XFe24 Analyzer (Outros) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2020/11/05 - 2020/11/06 Training School: STRATACELL "3D cell models - a powerful tool to study MDR" Lietuvos sveikatos mokslu universitetas, Lithuania
2020/02/19 - 2020/03/04 Workshop: Introduction to Information Design for Life Sciences Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2019/12/03 - 2019/12/03 Conferences in Oncobiology 2019/2020 Universidade do Porto Faculdade de Farmácia, Portugal
Distinctions

Award

2019 Programa IACOBUS - Publicações Científicas (Papers)
Agrupamento Europeu de Cooperação Territorial – Galicia-Norte de Portugal (GNP-AECT), Spain