Identification
Personal identification
- Full name
- Fábio Miguel Figueiredo Santos
Citation names
- Fábio M. F. Santos
Author identifiers
- Ciência ID
- 8C1F-2DFC-4A67
- ORCID iD
- 0000-0002-9057-9276
- Researcher Id
- B-7028-2016
- Scopus Author Id
- 55645426300
Email addresses
- fmfsantos1987@gmail.com (Professional)
Addresses
- Pharmacy Faculty - Lisbon University. Av. Prof. Gama Pinto, 1649-003, Lisbon, Lisboa, Portugal (Professional)
Websites
Knowledge fields
- Medical and Health Sciences - Basic Medicine - Medicinal Chemistry
- Exact Sciences - Chemical Sciences - Organic Chemistry
- Natural sciences - Biological Sciences - Biochemistry
- Exact Sciences - Chemical Sciences - Analytical Chemistry
Languages
Language | Speaking | Reading | Writing | Listening | Peer-review |
---|---|---|---|---|---|
English | Advanced (C1) | Advanced (C1) | Advanced (C1) | Advanced (C1) |
Education
Degree | Classification | |
---|---|---|
2014/03/01 - 2018/12/06
Concluded
|
Farmácia (Doutoramento)
Major in Pharmaceutical and Medicinal chemistry
Universidade de Lisboa Faculdade de Farmácia, Portugal
"Iminoboronates as useful scaffolds for tumor-targeting" (THESIS/DISSERTATION)
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Aprovado com distinção e louvor |
2009/10/06 - 2012/02/27
Concluded
|
Pharmaceutical and Medicinal chemistry (Mestrado)
Universidade de Lisboa Faculdade de Farmácia, Portugal
"Triazene Prodrug Synthesis for MDEPT Strategy and their Hepatotoxic Evaluation" (THESIS/DISSERTATION)
|
17 |
2005/09 - 2009/08
Concluded
|
Biochemistry (Licenciatura)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
"Estudos Bioquímicos de uma Dps recombinante de Pseudomonas nautica 617" (THESIS/DISSERTATION)
|
14 |
Affiliation
Science
Category Host institution |
Employer | |
---|---|---|
2022/05 - Current | Contracted Researcher (Research) | Universidade de Lisboa Faculdade de Farmácia, Portugal |
Teaching in Higher Education
Category Host institution |
Employer | |
---|---|---|
2023 - 2023 | Assistant (University Teacher) | Universidade de Lisboa Faculdade de Farmácia, Portugal |
Others
Category Host institution |
Employer | |
---|---|---|
2022/01 - 2022/05 | Analytical Scientist - Chemical Characterization | Hovione, Portugal |
2019/06/04 - 2021/12/31 | Pos-Doc fellow at iMed.ULisboa_FARM-ID 7/2019/PTDC/QUI-QOR/29967/2017; Btox: Boronated Cytotoxic Multivalent Platforms - A New Concept to Fight Cancer | Universidade de Lisboa Faculdade de Farmácia, Portugal |
Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal | ||
2018/08/01 - 2019/06/01 | Research fellow at iMed.ULisboa with a master grant (PTDC/QEQ-MED/5512/2014; Alzheimer3D: Trifunctional Conjugates for the Selective Drug Delivery in Alzheimer's disease | Universidade de Lisboa Faculdade de Farmácia, Portugal |
Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal | ||
2014/03/01 - 2018/03/01 | PhD student with a PhD scholarship (SFRH/BD/94779/2013; Iminoboronates as useful scaffolds for tumor-targeting) financed by FCT | Universidade de Lisboa Faculdade de Farmácia, Portugal |
2013/05/02 - 2014/02/28 | Research fellow with a master scholarship (PTDC/QUI-QUI/118315/2010; Borrow some boron: New strategies for Protein modification) financed by FCT | Universidade de Lisboa Faculdade de Farmácia, Portugal |
Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal | ||
2012/04/02 - 2013/03/31 | Research fellow with a master grant (PTDC/QUI-QUI/099389/2008; Please MOC it! Metal-Organo-Catalysis an emergent concept) financed by FCT | Universidade de Lisboa Faculdade de Farmácia, Portugal |
Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal | ||
2007/11/24 - 2008/02/24 | Monitor of Enzymatic Kinetic curricular unit during B.Sc in Biochemistry with a scientific initiation scholarships financed by FCT. | Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal |
Projects
Grant
Designation | Funders | |
---|---|---|
2022/01/17 - 2025/01/16 | SmartBox: Engineering the first generation of ROS responsive ADCs
PTDC/QUI-OUT/3989/2021
Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal |
Fundação para a Ciência e a Tecnologia
Ongoing
|
2022/01 - 2025/01 | SmartBox: Desenvolvimento da primeira geração de ADCs sensíveis a ROS
Provided by PTCRIS: PTDC/QUI-OUT/3989/2021
|
Fundação para a Ciência e a Tecnologia |
2017/01 - 2021/06 | ONCOLOGIA DE PRECISÃO: TERAPIAS E TECNOLOGIAS INOVADORAS
Provided by PTCRIS: SAICTPAC/0019/2015
|
Fundação para a Ciência e a Tecnologia |
2018/08/01 - 2019/06/01 | Alzheimer3D: Trifunctional Conjugates for the Selective Drug Delivery in Alzheimer's disease
PTDC/QEQ-MED/5512/2014
Master Student Fellow
|
Fundação para a Ciência e a Tecnologia
Concluded
|
2014/03 - 2018/05 | IMINOBORONATES AS USEFUL SCAFFOLDS FOR TUMOR-TARGETING
Provided by PTCRIS: SFRH/BD/94779/2013
|
Fundação para a Ciência e a Tecnologia |
2013/05 - 2014/02 | Borrow some boron: New strategies for Protein modification
PTDC/QUI-QUI/118315/2010
Master Student Fellow
Universidade de Lisboa Faculdade de Farmácia, Portugal
|
Fundação para a Ciência e a Tecnologia
Concluded
|
2012/04 - 2013/03 | Please MOC it! Metal-Organo-Catalysis an emergent concept
PTDC/QUI-QUI/099389/2008
Master Student Fellow
Universidade de Lisboa Faculdade de Farmácia, Portugal
|
Fundação para a Ciência e a Tecnologia
Concluded
|
2007/11/24 - 2008/02/24 | Monitor of Enzymatic Kinetic classes during graduation in Biochemistry
...
Other
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
|
REQUIMTE
Concluded
|
Contract
Designation | Funders | |
---|---|---|
2018/07/02 - 2021/07/01 | Boronated Cytotoxic Multivalent Platforms - A New Concept to Fight Cancer
PTDC/QUI-QOR/29967/2017
Researcher
|
Ongoing
|
2017/01/01 - 2021/06/30 | PRECISION ONCOLOGY BY INNOVATIVE THERAPIES AND TECHNOLOGIES
SAICTPAC/0019/2015
Instituto Politécnico de Leiria, Portugal
Universidade de Coimbra, Portugal Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal INESC Microsistemas e Nanotecnologias, Portugal Universidade de Lisboa Faculdade de Farmácia, Portugal |
Fundação para a Ciência e a Tecnologia
Ongoing
|
2019/06/04 - 2020 | Btox: Boronated Cytotoxic Multivalent Platforms - A New Concept to Fight Cancer
PTDC/QUI-QOR/29967/2017
Post-doc Fellow
Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
|
Fundação para a Ciência e a Tecnologia
Ongoing
|
2019/01/01 - 2019/12/31 | Instituto de Investigação do Medicamento
UID/DTP/04138/2019
154706UID
Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
Universidade de Lisboa Faculdade de Farmácia, Portugal |
Fundação para a Ciência e a Tecnologia
Concluded
|
Outputs
Publications
Book chapter |
|
Conference poster |
|
Journal article |
|
Thesis / Dissertation |
|
Intellectual property
Patent |
|
Activities
Oral presentation
Presentation title | Event name Host (Event location) |
|
---|---|---|
2023/07/25 | BASHY platform: Bioimaging and Therapeutics | XXVIII Encontro Nacional da SPQ
SPQ (Aveiro, Portugal)
|
2022/07 | BASHY as a valuable fluorescent linker for drug conjugates | CQUL 5th Meeting - Forging Bonds
(Lisbon, Portugal)
|
2020 | Boron's Modular Technology: Therapeutics and Bioimaging | JorTec Bioquímica 2020
(Lisboa, Portugal)
|
2019 | BASHY – A Multifunctional Modular Fluorophore Platform | 4th Encontro do Colégio de Química da ULisboa
(Lisboa, Portugal)
|
2017 | Modular Assembly of Reversible Multivalent Targeting Drug Conjugates | EFMC-YMCS 2017, Young Medicinal Chemist Symposium
(Vienna, Austria)
|
2017 | Boron-promoted Modular Assembly of Reversible and Multivalent Tumor-Targeting Drug Conjugates | 2nd Encontro do Colégio de Química da ULisboa
(Lisboa, Portugal)
|
2016 | A Three-Component Assembly Promoted by Boronic Acids Delivers a Modular Fluorophore Platform (BASHY Dyes) | 8th Postgraduate iMed.ULisboa Students Meeting
(Lisboa, Portugal)
|
Supervision
Thesis Title Role |
Degree Subject (Type) Institution / Organization |
|
---|---|---|
2015 - 2016 | Development of new boron based fluorescent dyes as hydrogen sulphide probes
Co-supervisor
|
Integrated Master in Pharmaceutical Sciences (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
|
Event organisation
Event name Type of event (Role) |
Institution / Organization | |
---|---|---|
2017/07 - 2017/07 | XXV Encontro Nacional da Sociedade Portuguesa de Quimica (XXV ENSPQ) (2017/07 - 2017/07)
Conference (Member of the Organising Committee)
|
|
2015/06 - 2015/06 | 6th European Conference on Chemistry in Life Sciences (6th ECCLS) (2015/06 - 2015/06)
Conference (Member of the Organising Committee)
|
|
2014/09 - 2014/09 | XXIII International Symposium on Medicinal Chemistry and 1st EFMC Young Medicinal Chemist Symposium (2014/09 - 2014/09)
Conference (Member of the Organising Committee)
|
|
2013/09 - 2013/09 | 10th Portuguese National Meeting of Organic Chemistry and the 1st Portuguese-Brazilian Organic Chemistry Symposium (2013/09 - 2013/09)
Conference (Member of the Organising Committee)
|
Jury of academic degree
Topic Role |
Candidate name (Type of degree) Institution / Organization |
|
---|---|---|
2022 | Targeting tumour cells usings chemical linkers with boronic acids and diazaborine scaffolds
(Thesis) Arguer
|
Ricardo Simões Dos Santos (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
|
2020 | Synthesis and Evaluation of New Boronated Cytotoxic Platforms
(Thesis) Arguer
|
João Pedro Lavado Fernandes (Master) |
Association member
Society Organization name | Role | |
---|---|---|
2013 - 2015 | Postgraduate Students Comission (ipSC) do Instituto de Investigação do Medicamento (iMed.ULisboa) da FFULisboa | Commission member |
Interview (newspaper / magazine)
Activity description | Newspaper / Forum | |
---|---|---|
2017/10/02 | Modular construction of cytotoxic bioconjugates with high selectivity towards cancer cells | Associação Portuguesa de Investigação em Cancro (ASPIC) |
Mentoring / Tutoring
Topic | Student name | |
---|---|---|
2023 - 2023 | Síntese de complexos de boro fotoativados para aplicações biológicas | Eduardo Filipe Fernandes dos Reis |
2023 - 2023 | BASHY, as a new tool for ChemBio | Ana Catarina Santos |
2022 - 2022 | BASHY as a novel platform for fluorescent and radiolabeled probes | JOÃO ESTRÍBIO LEITE |
2021 - 2021 | Modular Synthesis of a new Fluorescent dye (BASHY) | João Francisco Alves Falcão Felicidade |
2020 - 2020 | Modular Synthesis of a new Fluorescent dye (BASHY) | João Francisco Alves Falcão Felicidade |
2019 - 2019 | Synthesis and Evaluation of New Boronated Cytotoxic Platforms | João Pedro Lavado Fernandes |
2018 - 2019 | Modular Synthesis of Fluorescent Probe (BASHY) | João Pedro Lavado Fernandes |
2017 - 2017 | Iminoboronate synthesis: Construction of BASHY dyes to be applied in bioimaging | Rita Isabel Cordeiro Padanha |
2017 - 2017 | Modular Synthesis of Fluoresecent Probes (BASHY) for Bioimaging Applications | João Manuel Oliveira Mota |
2016 - 2016 | BASHY as hydrogen sulphide probes | Joana Inês Coelho de Pinho Carvalho |
2015 - 2015 | Strategy for cancer cells targeting: iminoboronates conjugates and imaging probes | Joana Inês Coelho de Pinho Carvalho |
2015 - 2015 | Development of a pegylated building block for the assemblage of conjugates for cancer's therapy | Rita Isabel Cordeiro Padanha |
Other jury / evaluation
Activity description | Institution / Organization | |
---|---|---|
2023 - 2033 | Assessment of a FFUL master student’s research project titled “BASHY, as a new tool for ChemBio”. Student name: Ana Catarina Santos | Universidade de Lisboa Faculdade de Farmácia, Portugal |
2023 - 2023 | Evaluation of a FFUL bachelor student’s research project titled “Synthesis of a 2-acetylphenylboronic acid derivative for the preparation of polymer bioconjugates”. Student Name: Ana Maria Narancic Marques | Universidade de Lisboa Faculdade de Farmácia, Portugal |
2021 - 2021 | Evaluation of a FFUL bachelor student’s research project titled “Synthesis of iminoboronate cross linkers”. Student name: Ana Maria Narancic Marques | Universidade de Lisboa Faculdade de Farmácia, Portugal |
Distinctions
Award
2018 | Best poster presentation
12ENQO/5ENQT, Portugal
|
Title
2017 | Young medicinal chemist in Portugal
Direcção da Divisão de Química Terapêutica da Sociedade Portuguesa Química, Portugal
|