Journal article |
- Gabriel E Valdebenito; Anitta R Chacko; Michael R Duchen. "The mitochondrial ATP synthase as an ATP consumer—a surprising
therapeutic target". The EMBO Journal (2023): https://doi.org/10.15252/embj.2023114141.
10.15252/embj.2023114141
- Liliana M. Almeida; Brígida R. Pinho; Michael R. Duchen; Jorge M. A. Oliveira. "The PERKs of mitochondria protection during
stress: insights for PERK modulation in neurodegenerative and metabolic diseases". Biological Reviews (2022): https://doi.org/10.1111/brv.12860.
10.1111/brv.12860
- "Paradoxical neuronal hyperexcitability in a mouse model of mitochondrial pyruvate import deficiency". eLife 11 (2022):
http://dx.doi.org/10.7554/elife.72595.
10.7554/elife.72595
- Chi H; Bhosale G; Duchen MR. "Assessing the Redox Status of Mitochondria Through the NADH/FAD2+ Ratio
in Intact Cells.". Methods in molecular biology (Clifton, N.J.) (2022): http://europepmc.org/abstract/med/35771452.
10.1007/978-1-0716-2309-1_21
- "Constitutive activation of the PI3K-Akt-mTORC1 pathway sustains the m.3243¿A¿>¿G mtDNA mutation". Nature Communications
12 1 (2021): http://dx.doi.org/10.1038/s41467-021-26746-2.
10.1038/s41467-021-26746-2
- "Allosteric activation of Hsp70 reduces mutant huntingtin levels, the clustering of N-terminal fragments, and their nuclear
accumulation". Life Sciences 285 (2021): 120009-120009. http://dx.doi.org/10.1016/j.lfs.2021.120009.
10.1016/j.lfs.2021.120009
- "Rewiring cell signalling pathways in pathogenic mtDNA mutations". Trends in Cell Biology (2021): http://dx.doi.org/10.1016/j.tcb.2021.10.005.
10.1016/j.tcb.2021.10.005
- "Selective mitochondrial antioxidant MitoTEMPO reduces renal dysfunction and systemic inflammation in experimental sepsis
in rats". British Journal of Anaesthesia 127 4 (2021): 577-586. http://dx.doi.org/10.1016/j.bja.2021.05.036.
10.1016/j.bja.2021.05.036
- "The spectrum of neurodevelopmental, neuromuscular and neurodegenerative disorders due to defective autophagy". Autophagy
(2021): 1-22. http://dx.doi.org/10.1080/15548627.2021.1943177.
10.1080/15548627.2021.1943177
- "Activation of the Integrated Stress Response and ER Stress Protect from Fluorizoline-Induced Apoptosis in HEK293T and U2OS
Cell Lines". International Journal of Molecular Sciences 22 11 (2021): 6117-6117. http://dx.doi.org/10.3390/ijms22116117.
10.3390/ijms22116117
- "Excitotoxicity Revisited: Mitochondria on the Verge of a Nervous Breakdown". Trends in Neurosciences 44 5 (2021):
342-351. http://dx.doi.org/10.1016/j.tins.2021.01.001.
10.1016/j.tins.2021.01.001
- "MitoSegNet: Easy-to-use Deep Learning Segmentation for Analyzing Mitochondrial Morphology". iScience 23 10 (2020):
101601-101601. http://dx.doi.org/10.1016/j.isci.2020.101601.
10.1016/j.isci.2020.101601
- "Mitochondrial Signature in Human Monocytes and Resistance to Infection in C. elegans During Fumarate-Induced Innate Immune
Training". Frontiers in Immunology 11 (2020): http://dx.doi.org/10.3389/fimmu.2020.01715.
10.3389/fimmu.2020.01715
- "Mitochondria: An Integrative Hub Coordinating Circadian Rhythms, Metabolism, the Microbiome, and Immunity". Frontiers
in Cell and Developmental Biology 8 (2020): http://dx.doi.org/10.3389/fcell.2020.00051.
10.3389/fcell.2020.00051
- Duchen, Michael. "Multiphoton NAD(P)H FLIM reveals metabolic changes in individual cell types of the intact cochlea upon sensorineural
hearing loss.". Scientific reports (2019): https://europepmc.org/articles/PMC6906381.
10.1038/s41598-019-55329-x
- Sean M. Davidson; Gyorgy Szabadkai; Michael R. Duchen. "Fantastic beasts and how to find them—Molecular identification of
the mitochondrial ATP-sensitive potassium channel". Cell Calcium 84 (2019): 102100-102100. https://doi.org/10.1016/j.ceca.2019.102100.
10.1016/j.ceca.2019.102100
- Duchen, Michael. "Impaired cellular bioenergetics caused by GBA1 depletion sensitizes neurons to calcium overload.". Cell
death and differentiation (2019): https://doi.org/10.1038/s41418-019-0442-2.
10.1038/s41418-019-0442-2
- Duchen, Michael. "A key metabolic integrator, coenzyme A, modulates the activity of peroxiredoxin 5 via covalent modification.".
Molecular and cellular biochemistry (2019): https://europepmc.org/articles/PMC6790197.
10.1007/s11010-019-03593-w
- Duchen, Michael. "Diabetes causes marked inhibition of mitochondrial metabolism in pancreatic ß-cells.". Nature communications
(2019): https://europepmc.org/articles/PMC6554411.
10.1038/s41467-019-10189-x
- Duchen, Michael. "Polarized Two-Photon Absorption and Heterogeneous Fluorescence Dynamics in NAD(P)H.". The journal of
physical chemistry. B (2019): https://europepmc.org/articles/PMC6558641.
10.1021/acs.jpcb.9b01236
- Duchen, Michael. "Investigating the Mitochondrial Permeability Transition Pore in Disease Phenotypes and Drug Screening.".
Current protocols in pharmacology (2019): https://doi.org/10.1002/cpph.59.
10.1002/cpph.59
- Duchen, Michael. "Modelling mitochondrial dysfunction in Alzheimer's disease using human induced pluripotent stem cells.".
World journal of stem cells (2019): https://europepmc.org/articles/PMC6545525.
10.4252/wjsc.v11.i5.236
- Pollard AE; Martins L; Muckett PJ; Khadayate S; Bornot A; Clausen M; Admyre T; et al. "AMPK activation protects against diet
induced obesity through Ucp1-independent thermogenesis in subcutaneous white adipose tissue.". Nature metabolism (2019):
http://europepmc.org/abstract/med/30887000.
10.1038/s42255-019-0036-9
- Duchen, Michael. "Metabolic Profiling of Live Cancer Tissues Using NAD(P)H Fluorescence Lifetime Imaging.". Methods in
molecular biology (Clifton, N.J.) (2019): https://doi.org/10.1007/978-1-4939-9027-6_19.
10.1007/978-1-4939-9027-6_19
- Duchen, Michael. "Mitochondrial Permeability Transition: A Molecular Lesion with Multiple Drug Targets.". Trends in pharmacological
sciences (2018): https://doi.org/10.1016/j.tips.2018.11.004.
10.1016/j.tips.2018.11.004
- Soares TR; Reis SD; Pinho BR; Duchen MR; Oliveira JMA. "Targeting the proteostasis network in Huntington's disease.". Ageing
research reviews (2018): http://europepmc.org/abstract/med/30502498.
10.1016/j.arr.2018.11.006
- Duchen, Michael. "The role of mitochondria in sepsis-induced cardiomyopathy.". Biochimica et biophysica acta. Molecular
basis of disease (2018): https://doi.org/10.1016/j.bbadis.2018.10.011.
10.1016/j.bbadis.2018.10.011
- Martin W. Nicholson; Aaron Sweeney; Eva Pekle; Sabina Alam; Afia B. Ali; Michael Duchen; Jasmina N. Jovanovic. "Diazepam-induced
loss of inhibitory synapses mediated by PLCd/ Ca2+/calcineurin signalling downstream of GABAA receptors". Molecular Psychiatry
23 9 (2018): 1851-1867. https://doi.org/10.1038/s41380-018-0100-y.
10.1038/s41380-018-0100-y
- Duchen, Michael. "Promoting the clearance of neurotoxic proteins in neurodegenerative disorders of ageing.". Nature reviews.
Drug discovery (2018): https://europepmc.org/articles/PMC6456907.
10.1038/nrd.2018.109
- Duchen, Michael. "Inositol trisphosphate receptor-mediated Ca2+ signalling stimulates mitochondrial function and gene expression
in core myopathy patients.". Human molecular genetics (2018): https://europepmc.org/articles/PMC6005141.
10.1093/hmg/ddy149
- Duchen, Michael. "Decellularized Cartilage Directs Chondrogenic Differentiation: Creation of a Fracture Callus Mimetic.".
Tissue engineering. Part A (2018): https://doi.org/10.1089/ten.TEA.2017.0450.
10.1089/ten.tea.2017.0450
- Corrochano S; Blanco G; Williams D; Wettstein J; Simon M; Kumar S; Moir L; et al. "A genetic modifier suggests that endurance
exercise exacerbates Huntington's disease.". Human molecular genetics (2018): http://europepmc.org/abstract/med/29509900.
10.1093/hmg/ddy077
- Duchen, Michael. "Three-Dimensional Human iPSC-Derived Artificial Skeletal Muscles Model Muscular Dystrophies and Enable Multilineage
Tissue Engineering.". Cell reports (2018): https://europepmc.org/articles/PMC5917451.
10.1016/j.celrep.2018.03.091
- Duchen, Michael. "Renal Tubular Cell Mitochondrial Dysfunction Occurs Despite Preserved Renal Oxygen Delivery in Experimental
Septic Acute Kidney Injury.". Critical care medicine (2018): https://europepmc.org/articles/PMC5856355.
10.1097/CCM.0000000000002937
- Duchen, Michael. "The APPswe/PS1A246E mutations in an astrocytic cell line leads to increased vulnerability to oxygen and
glucose deprivation, Ca2+ dysregulation, and mitochondrial abnormalities.". Journal of neurochemistry (2018): https://doi.org/10.1111/jnc.14293.
10.1111/jnc.14293
- Sajic M; Ida KK; Canning R; Gregson NA; Duchen MR; Smith KJ. "Mitochondrial damage and "plugging" of transport selectively
in myelinated, small-diameter axons are major early events in peripheral neuroinflammation.". Journal of neuroinflammation
(2018): http://europepmc.org/abstract/med/29486771.
10.1186/s12974-018-1094-8
- Davidson SM; Duchen MR. "Imaging Mitochondrial Calcium Fluxes with Fluorescent Probes and Single- or Two-Photon Confocal Microscopy.".
Methods in molecular biology (Clifton, N.J.) (2018): http://europepmc.org/abstract/med/29851000.
10.1007/978-1-4939-7831-1_10
- Duchen, Michael. "Crosstalk between Lysosomes and Mitochondria in Parkinson's Disease.". Frontiers in cell and developmental
biology (2017): https://europepmc.org/articles/PMC5732996.
10.3389/fcell.2017.00110
- Duchen, Michael. "Guidelines on experimental methods to assess mitochondrial dysfunction in cellular models of neurodegenerative
diseases.". Cell death and differentiation (2017): https://europepmc.org/articles/PMC5864235.
10.1038/s41418-017-0020-4
- Duchen, Michael. "Protection of cerebral microcirculation, mitochondrial function, and electrocortical activity by small-volume
resuscitation with terlipressin in a rat model of haemorrhagic shock.". British journal of anaesthesia (2017): https://doi.org/10.1016/j.bja.2017.11.074.
10.1016/j.bja.2017.11.074
- Duchen, Michael. "Mitochondrial permeability transition pore: sensitivity to opening and mechanistic dependence on substrate
availability.". Scientific reports (2017): https://europepmc.org/articles/PMC5585167.
10.1038/s41598-017-10673-8
- Pinto BB; Dyson A; Umbrello M; Carré JE; Ritter C; Clatworthy I; Duchen MR; Singer M. "Improved Survival in a Long-Term Rat
Model of Sepsis Is Associated With Reduced Mitochondrial Calcium Uptake Despite Increased Energetic Demand.". Critical
care medicine (2017): http://europepmc.org/abstract/med/28410346.
10.1097/ccm.0000000000002448
- Tsuchiya Y; Peak-Chew SY; Newell C; Miller-Aidoo S; Mangal S; Zhyvoloup A; Bakovic J; et al. "Protein CoAlation: a redox-regulated
protein modification by coenzyme A in mammalian cells.". The Biochemical journal (2017): http://europepmc.org/abstract/med/28341808.
10.1042/bcj20170129
- Kon S; Ishibashi K; Katoh H; Kitamoto S; Shirai T; Tanaka S; Kajita M; et al. "Cell competition with normal epithelial cells
promotes apical extrusion of transformed cells through metabolic changes.". Nature cell biology (2017): http://europepmc.org/abstract/med/28414314.
10.1038/ncb3509
- Foote JR; Levine AP; Behe P; Duchen MR; Segal AW. "Imaging the Neutrophil Phagosome and Cytoplasm Using a Ratiometric pH Indicator.".
Journal of visualized experiments : JoVE (2017): http://europepmc.org/abstract/med/28448042.
10.3791/55107
- Blacker TS; Berecz T; Duchen MR; Szabadkai G. "Assessment of Cellular Redox State Using NAD(P)H Fluorescence Intensity and
Lifetime.". Bio-protocol (2017): http://europepmc.org/abstract/med/28286806.
10.21769/bioprotoc.2105
- McKenzie M; Lim SC; Duchen MR. "Simultaneous Measurement of Mitochondrial Calcium and Mitochondrial Membrane Potential in
Live Cells by Fluorescent Microscopy.". Journal of visualized experiments : JoVE (2017): http://europepmc.org/abstract/med/28190045.
10.3791/55166
- Plotegher N; Duchen MR. "Mitochondrial Dysfunction and Neurodegeneration in Lysosomal Storage Disorders.". Trends in molecular
medicine (2017): http://europepmc.org/abstract/med/28111024.
10.1016/j.molmed.2016.12.003
- Bhosale G; Sharpe JA; Koh A; Kouli A; Szabadkai G; Duchen MR. "Pathological consequences of MICU1 mutations on mitochondrial
calcium signalling and bioenergetics.". Biochimica et biophysica acta. Molecular cell research (2017): http://europepmc.org/abstract/med/28132899.
10.1016/j.bbamcr.2017.01.015
- Blacker TS; Chen W; Avezov E; Marsh RJ; Duchen MR; Kaminski CF; Bain AJ. "Investigating State Restriction in Fluorescent Protein
FRET Using Time-Resolved Fluorescence and Anisotropy.". The journal of physical chemistry. C, Nanomaterials and interfaces
(2016): http://europepmc.org/abstract/med/28217242.
10.1021/acs.jpcc.6b11235
- Chisholm KI; Ida KK; Davies AL; Tachtsidis I; Papkovsky DB; Dyson A; Singer M; Duchen MR; Smith KJ. "Hypothermia protects
brain mitochondrial function from hypoxemia in a murine model of sepsis.". (2016): http://europepmc.org/abstract/med/26661160.
10.1177/0271678x15606457
- Briston T; Lewis S; Koglin M; Mistry K; Shen Y; Hartopp N; Katsumata R; et al. "Identification of ER-000444793, a Cyclophilin
D-independent inhibitor of mitochondrial permeability transition, using a high-throughput screen in cryopreserved mitochondria.".
(2016): http://europepmc.org/abstract/med/27886240.
10.1038/srep37798
- Blacker TS; Duchen MR. "Investigating mitochondrial redox state using NADH and NADPH autofluorescence.". (2016): http://europepmc.org/abstract/med/27519271.
10.1016/j.freeradbiomed.2016.08.010
- Bolaños JP; Cadenas E; Duchen MR; Hampton MB; Mann GE; Murphy MP. "Introduction to Special Issue on Mitochondrial Redox Signaling
in Health and Disease.". (2016): http://europepmc.org/abstract/med/27502830.
10.1016/j.freeradbiomed.2016.08.004
- Guedes-Dias P; Pinho BR; Soares TR; de Proença J; Duchen MR; Oliveira JM. "Mitochondrial dynamics and quality control in Huntington's
disease.". (2016): http://europepmc.org/abstract/med/26388396.
10.1016/j.nbd.2015.09.008
- Corona JC; Duchen MR. "PPAR¿ as a therapeutic target to rescue mitochondrial function in neurological disease.". (2016): http://europepmc.org/abstract/med/27352979.
10.1016/j.freeradbiomed.2016.06.023
- Tosatto A; Sommaggio R; Kummerow C; Bentham RB; Blacker TS; Berecz T; Duchen MR; et al. "The mitochondrial calcium uniporter
regulates breast cancer progression via HIF-1a.". (2016): http://europepmc.org/abstract/med/27138568.
10.15252/emmm.201606255
- Hawkins KE; Joy S; Delhove JM; Kotiadis VN; Fernandez E; Fitzpatrick LM; Whiteford JR; et al. "NRF2 Orchestrates the Metabolic
Shift during Induced Pluripotent Stem Cell Reprogramming.". (2016): http://europepmc.org/abstract/med/26904936.
10.1016/j.celrep.2016.02.003
- Warne J; Pryce G; Hill JM; Shi X; Lennerås F; Puentes F; Kip M; et al. "Selective Inhibition of the Mitochondrial Permeability
Transition Pore Protects against Neurodegeneration in Experimental Multiple Sclerosis.". (2016): http://europepmc.org/abstract/med/26679998.
10.1074/jbc.m115.700385
- Kilpatrick BS; Magalhaes J; Beavan MS; McNeill A; Gegg ME; Cleeter MW; Bloor-Young D; et al. "Endoplasmic reticulum and lysosomal
Ca²¿ stores are remodelled in GBA1-linked Parkinson disease patient fibroblasts.". (2016): http://europepmc.org/abstract/med/26691915.
10.1016/j.ceca.2015.11.002
- Klionsky DJ; Abdelmohsen K; Abe A; Abedin MJ; Abeliovich H; Acevedo Arozena A; Adachi H; et al. "Guidelines for the use and
interpretation of assays for monitoring autophagy (3rd edition).". (2016): http://europepmc.org/abstract/med/26799652.
10.1080/15548627.2015.1100356
- Chisholm KI; Ida KK; Davies AL; Papkovsky DB; Singer M; Dyson A; Tachtsidis I; Duchen MR; Smith KJ. "In Vivo Imaging of Flavoprotein
Fluorescence During Hypoxia Reveals the Importance of Direct Arterial Oxygen Supply to Cerebral Cortex Tissue.". (2016): http://europepmc.org/abstract/med/26782217.
10.1007/978-1-4939-3023-4_29
- McKenzie M; Duchen MR. "Impaired Cellular Bioenergetics Causes Mitochondrial Calcium Handling Defects in MT-ND5 Mutant Cybrids.".
(2016): http://europepmc.org/abstract/med/27110715.
10.1371/journal.pone.0154371
- Sadeghian M; Mastrolia V; Rezaei Haddad A; Mosley A; Mullali G; Schiza D; Sajic M; et al. "Mitochondrial dysfunction is an
important cause of neurological deficits in an inflammatory model of multiple sclerosis.". (2016): http://europepmc.org/abstract/med/27624721.
10.1038/srep33249
- Davidson SM; Foote K; Kunuthur S; Gosain R; Tan N; Tyser R; Zhao YJ; et al. "Inhibition of NAADP signalling on reperfusion
protects the heart by preventing lethal calcium oscillations via two-pore channel 1 and opening of the mitochondrial permeability
transition pore.". (2015): http://europepmc.org/abstract/med/26395965.
10.1093/cvr/cvv226
- Guedes-Dias P; de Proença J; Soares TR; Leitão-Rocha A; Pinho BR; Duchen MR; Oliveira JM. "HDAC6 inhibition induces mitochondrial
fusion, autophagic flux and reduces diffuse mutant huntingtin in striatal neurons.". (2015): http://europepmc.org/abstract/med/26300485.
10.1016/j.bbadis.2015.08.012
- Shahni R; Cale CM; Anderson G; Osellame LD; Hambleton S; Jacques TS; Wedatilake Y; et al. "Signal transducer and activator
of transcription 2 deficiency is a novel disorder of mitochondrial fission.". (2015): http://europepmc.org/abstract/med/26122121.
10.1093/brain/awv182
- Nickel AG; von Hardenberg A; Hohl M; Löffler JR; Kohlhaas M; Becker J; Reil JC; et al. "Reversal of Mitochondrial Transhydrogenase
Causes Oxidative Stress in Heart Failure.". (2015): http://europepmc.org/abstract/med/26256392.
10.1016/j.cmet.2015.07.008
- Bhosale G; Sharpe JA; Sundier SY; Duchen MR. "Calcium signaling as a mediator of cell energy demand and a trigger to cell
death.". (2015): http://europepmc.org/abstract/med/26375864.
10.1111/nyas.12885
- Ikaga R; Namekata I; Kotiadis VN; Ogawa H; Duchen MR; Tanaka H; Iida-Tanaka N. "Knockdown of aquaporin-8 induces mitochondrial
dysfunction in 3T3-L1 cells.". Biochemistry and biophysics reports (2015): http://europepmc.org/abstract/med/29124204.
10.1016/j.bbrep.2015.09.009
- Zolfaghari PS; Carré JE; Parker N; Curtin NA; Duchen MR; Singer M. "Skeletal muscle dysfunction is associated with derangements
in mitochondrial bioenergetics (but not UCP3) in a rodent model of sepsis.". (2015): http://europepmc.org/abstract/med/25714676.
10.1152/ajpendo.00562.2014
- Corona JC; Duchen MR. "Impaired mitochondrial homeostasis and neurodegeneration: towards new therapeutic targets?". (2015):
http://europepmc.org/abstract/med/25216534.
10.1007/s10863-014-9576-6
- Llorente-Folch I; Rueda CB; Pardo B; Szabadkai G; Duchen MR; Satrustegui J. "The regulation of neuronal mitochondrial metabolism
by calcium.". (2015): http://europepmc.org/abstract/med/25809592.
10.1113/JP270254
- Corona JC; Duchen MR. "PPAR¿ and PGC-1a as therapeutic targets in Parkinson's.". (2015): http://europepmc.org/abstract/med/25007880.
10.1007/s11064-014-1377-0
- Majumder P; Duchen MR; Gale JE. "Cellular glutathione content in the organ of Corti and its role during ototoxicity.". (2015):
http://europepmc.org/abstract/med/25972783.
10.3389/fncel.2015.00143
- Levine AP; Duchen MR; de Villiers S; Rich PR; Segal AW. "Alkalinity of Neutrophil Phagocytic Vacuoles Is Modulated by HVCN1
and Has Consequences for Myeloperoxidase Activity.". (2015): http://europepmc.org/abstract/med/25885273.
10.1371/journal.pone.0125906
- Chouchani ET; Pell VR; Gaude E; Aksentijevic D; Sundier SY; Robb EL; Logan A; et al. "Ischaemic accumulation of succinate
controls reperfusion injury through mitochondrial ROS.". (2014): http://europepmc.org/abstract/med/25383517.
10.1038/nature13909
- Schwarzländer M; Wagner S; Ermakova YG; Belousov VV; Radi R; Beckman JS; Buettner GR; et al. "The 'mitoflash' probe cpYFP
does not respond to superoxide.". (2014): http://europepmc.org/abstract/med/25341790.
10.1038/nature13858
- Ida K; Malbouisson L; Otsuki D; Chisholm K; Dyson A; Singer M; Duchen M; Smith K. "0036. Confocal imaging of impaired mitochondrial
function in the cerebral cortex of rats during haemorrhagic shock in vivo". Intensive care medicine experimental (2014):
http://europepmc.org/abstract/PMC/PMC4797095.
- Greco E; Arulkumaran N; Sixma M; Courtneidge H; Duchen M; Tam F; Unwin R; Singer M. "0889. Mitochondrial dysfunction contributes
to sepsis-induces acute kidney injury". Intensive care medicine experimental (2014): http://europepmc.org/abstract/PMC/PMC4796735.
- Chisholm K; Davies A; Singer M; Dyson A; Ida K; Tachtsidis I; Duchen M; Smith K. "0033. Hypothermia protects brain mitochondrial
function from hypoxia in sepsis". Intensive care medicine experimental (2014): http://europepmc.org/abstract/PMC/PMC4797910.
- Osellame LD; Duchen MR. "Quality control gone wrong: mitochondria, lysosomal storage disorders and neurodegeneration.". (2014):
http://europepmc.org/abstract/med/24116849.
10.1111/bph.12453
- Corona JC; de Souza SC; Duchen MR. "PPAR¿ activation rescues mitochondrial function from inhibition of complex I and loss
of PINK1.". (2014): http://europepmc.org/abstract/med/24374061.
10.1016/j.expneurol.2013.12.012
- Galvao J; Davis B; Tilley M; Normando E; Duchen MR; Cordeiro MF. "Unexpected low-dose toxicity of the universal solvent DMSO.".
(2014): http://europepmc.org/abstract/med/24327606.
10.1096/fj.13-235440
- Logan CV; Szabadkai G; Sharpe JA; Parry DA; Torelli S; Childs AM; Kriek M; et al. "Loss-of-function mutations in MICU1 cause
a brain and muscle disorder linked to primary alterations in mitochondrial calcium signaling.". (2014): http://europepmc.org/abstract/med/24336167.
10.1038/ng.2851
- Ivanes F; Faccenda D; Gatliff J; Ahmed AA; Cocco S; Cheng CH; Allan E; et al. "The compound BTB06584 is an IF1 -dependent
selective inhibitor of the mitochondrial F1 Fo-ATPase.". (2014): http://europepmc.org/abstract/med/24641180.
10.1111/bph.12638
- Blacker TS; Mann ZF; Gale JE; Ziegler M; Bain AJ; Szabadkai G; Duchen MR. "Separating NADH and NADPH fluorescence in live
cells and tissues using FLIM.". (2014): http://europepmc.org/abstract/med/24874098.
10.1038/ncomms4936
- Sajic M; Mastrolia V; Lee CY; Trigo D; Sadeghian M; Mosley AJ; Gregson NA; Duchen MR; Smith KJ. "Impulse conduction increases
mitochondrial transport in adult mammalian peripheral nerves in vivo.". (2013): http://europepmc.org/abstract/med/24391474.
10.1371/journal.pbio.1001754
- Kotiadis VN; Duchen MR; Osellame LD. "Mitochondrial quality control and communications with the nucleus are important in maintaining
mitochondrial function and cell health.". (2013): http://europepmc.org/abstract/med/24211250.
10.1016/j.bbagen.2013.10.041
- Alfieri A; Srivastava S; Siow RC; Cash D; Modo M; Duchen MR; Fraser PA; Williams SC; Mann GE. "Sulforaphane preconditioning
of the Nrf2/HO-1 defense pathway protects the cerebral vasculature against blood-brain barrier disruption and neurological
deficits in stroke.". (2013): http://europepmc.org/abstract/med/24017972.
10.1016/j.freeradbiomed.2013.08.190
- Osellame LD; Duchen MR. "Defective quality control mechanisms and accumulation of damaged mitochondria link Gaucher and Parkinson
diseases.". (2013): http://europepmc.org/abstract/med/23989665.
- Faccenda D; Tan CH; Duchen MR; Campanella M. "Mitochondrial IF1 preserves cristae structure to limit apoptotic cell death
signaling.". (2013): http://europepmc.org/abstract/med/23907134.
10.4161/cc.25840
- Zhou H; Rokach O; Feng L; Munteanu I; Mamchaoui K; Wilmshurst JM; Sewry C; et al. "RyR1 deficiency in congenital myopathies
disrupts excitation-contraction coupling.". (2013): http://europepmc.org/abstract/med/23553787.
10.1002/humu.22326
- Osellame LD; Rahim AA; Hargreaves IP; Gegg ME; Richard-Londt A; Brandner S; Waddington SN; Schapira AH; Duchen MR. "Mitochondria
and quality control defects in a mouse model of Gaucher disease--links to Parkinson's disease.". (2013): http://europepmc.org/abstract/med/23707074.
10.1016/j.cmet.2013.04.014
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