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PMajored in Biochemistry at the Faculty of Sciences from the Universidade do Porto in Portugal. PhD in Biomedical Sciences at the Katholieke Universiteit Leuven in Belgium trough the PhD program GABBA (Graduate program in Areas of Basic and Applied Biology) also from the Universidade do Porto. As a researcher, my domain of expertise were early developmental biology and the role of growth factors during development using mouse and embryonic stem cell models. Now, I changed gears and I work on clinical research. I am a clinical study coordinator and clinical data manager both in pharma- and in investigator-initiated clinical trials at Instituto de Medicina Molecular and Hematology Department of the Hospital de Santa Maria in Lisbon.
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Identification

Personal identification

Full name
Paulo Nelson Gomes Pereira

Citation names

  • Pereira, Paulo NG

Author identifiers

Ciência ID
8E10-EBAC-FC0E
ORCID iD
0000-0002-0930-0902

Email addresses

  • paulo.pereira@medicina.ulisboa.pt (Professional)

Telephones

Telephone
  • 217999570 Ext.: 47318 (Professional)

Addresses

  • Universidade de Lisboa, Faculdade de Medicina, Instituto de Medicina Molecular - IMM. Instituto de Medicina Molecular, Av. Prof. Egas Moniz, Edifício Egas Moniz, 1649-028, Lisboa, Lisboa, Portugal (Professional)

Knowledge fields

  • Natural sciences - Biological Sciences - Developmental Biology
  • Natural sciences - Biological Sciences - Molecular Biology
  • Medical and Health Sciences - Clinical Medicine - Hematology

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Spanish; Castilian Advanced (C1) Advanced (C1) Upper intermediate (B2) Advanced (C1)
Education
Degree Classification
2006 - 2011
Concluded
 Biomedical Sciences (Doutoramento)
Major in Developmental biology and TGF-beta/BMP signaling
Katholieke Universiteit Leuven Faculteit Geneeskunde, Belgium
"Antagonism of Nodal signaling by BMP/Smad5 prevents ectopic primitive streak formation in mice" (THESIS/DISSERTATION)
 Not Applicable
2001 - 2005
Concluded
 Biochemistry (Licenciatura)
Major in Applied Biochemistry
Universidade do Porto Faculdade de Ciências, Portugal
"Isolation and Purification of novel Peroxisomal Membrane Proteins (PMPs) from mouse and rat" (THESIS/DISSERTATION)
 15
Affiliation

Others

Category
Host institution 		Employer
2016/03 - Current Clinical Study Coordinator and Data Manager Instituto de Medicina Molecular João Lobo Antunes, Portugal
2014/11 - 2016/02 Postdoc (Research) Universidade Nova de Lisboa Centro de Estudos de Doenças Crónicas, Portugal
2012/04 - 2014/11 Postdoc (Research) Universidade do Algarve Departamento de Ciências Biomédicas e Medicina, Portugal
2006/09 - 2011/11 PhD Student Katholieke Universiteit Leuven Universitaire Ziekenhuizen Leuven Campus Gasthuisberg, Belgium
2005/01 - 2005/09 Undergraduate trainee Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
Projects

Grant

Designation Funders
2012 - 2016 Role of novel CHEP12 growth factor in the generation of cardiac tissue from ES cells
SFRH/BPD/87114/2012
Post-doc Fellow
Universidade do Algarve - Campus de Gambelas, Portugal

Universidade Nova de Lisboa Centro de Estudos de Doenças Crónicas, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2006/01 - 2011/09 Maintenance of Mesoderm and Amnion fate in the mouse embryo: an experimental developmental study
SFRH/BD/15901/2005
PhD Student Fellow
Katholieke Universiteit Leuven Universitaire Ziekenhuizen Leuven Campus Gasthuisberg, Belgium

Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
Fundação para a Ciência e a Tecnologia
Concluded

Contract

Designation Funders
2016/03 - Current Repair of tissue and organ damage in refractory chronic GVHD after hematopoietic stem cell transplantation by the infusion of purified allogeneic donor regulatory T lymphocytes (TREGeneration)
Grant agreement ID: 643776
Other
Instituto de Medicina Molecular João Lobo Antunes, Portugal
 Horizon 2020
Ongoing
Outputs

Publications

Journal article
  1. Campos, Cláudia F.; Leite, Luís; Pereira, Paulo N.G.; Vaz, Carlos Pinho; Branca, Rosa; Campilho, Fernando; Freitas, Fátima; et al. "PTX3 Polymorphisms Influence Cytomegalovirus Reactivation After Stem-Cell Transplantation". Frontiers in Immunology 10 (2019): http://dx.doi.org/10.3389/fimmu.2019.00088.
    10.3389/fimmu.2019.00088
  2. Soares, Maria V.; Azevedo, Rita I.; Ferreira, Inês A.; Bucar, Sara; Ribeiro, Ana C.; Vieira, Ana; Pereira, Paulo N.G.; et al. "Naive and stem cell memory T cell subset recovery reveals opposing reconstitution patterns in CD4 and CD8 T cells in chronic graft vs. Host disease". (2019): http://www.scopus.com/inward/record.url?scp=85063629820&partnerID=8YFLogxK.
    https://doi.org/10.3389/fimmu.2019.00334
  3. Bonet, Fernando; Pereira, Paulo N. G.; Bover, Oriol; Marques, Sara; Inácio, José M.; Belo, José A.. "CCBE1 is required for coronary vessel development and proper coronary artery stem formation in the mouse heart". Developmental Dynamics 247 10 (2018): 1135-1145. http://dx.doi.org/10.1002/dvdy.24670.
    10.1002/dvdy.24670
  4. Dobreva, Mariya P.; Abon Escalona, Vanesa; Lawson, Kirstie A.; Sanchez, Marina N.; Ponomarev, Ljuba C.; Pereira, Paulo N. G.; Stryjewska, Agata; et al. "Amniotic ectoderm expansion in mouse occurs via distinct modes and requires SMAD5-mediated signalling". Development 145 13 (2018): dev157222. http://dx.doi.org/10.1242/dev.157222.
    10.1242/dev.157222
  5. Bover, Oriol; Justo, Tiago; Pereira, Paulo N G; Facucho-Oliveira, João; Inácio, José M; Ramalho, José S; Domian, Ibrahim J; et al. "Loss of Ccbe1 affects cardiac-specification and cardiomyocyte differentiation in mouse embryonic stem cells". PloS one (2018): http://hdl.handle.net/10362/49616.
    https://doi.org/10.1371/journal.pone.0205108
  6. Pereira, P. N. G.; Dobreva, M. P.; Maas, E.; Cornelis, F. M.; Moya, I. M.; Umans, L.; Verfaillie, C. M.; et al. "Antagonism of Nodal signaling by BMP/Smad5 prevents ectopic primitive streak formation in the mouse amnion". Development 139 18 (2012): 3343-3354. http://dx.doi.org/10.1242/dev.075465.
    10.1242/dev.075465
  7. Moya, Iván M.; Umans, Lieve; Maas, Elke; Pereira, Paulo N.G.; Beets, Karen; Francis, Annick; Sents, Ward; et al. "Stalk Cell Phenotype Depends on Integration of Notch and Smad1/5 Signaling Cascades". Developmental Cell 22 3 (2012): 501-514. http://dx.doi.org/10.1016/j.devcel.2012.01.007.
    10.1016/j.devcel.2012.01.007
  8. Dobreva, Mariya P.; Lhoest, Larissa; Pereira, Paulo N. G.; Umans, Lieve; Chuva de Sousa Lopes, Susana M.; Zwijsen, An. "Periostin as a Biomarker of the Amniotic Membrane". Stem Cells International 2012 (2012): 1-10. http://dx.doi.org/10.1155/2012/987185.
    10.1155/2012/987185
  9. Conidi, Andrea; Cazzola, Silvia; Beets, Karen; Coddens, Kathleen; Collart, Clara; Cornelis, Frederique; Cox, Luk; et al. "Few Smad proteins and many Smad-interacting proteins yield multiple functions and action modes in TGFß/BMP signaling in vivo". Cytokine & Growth Factor Reviews 22 5-6 (2011): 287-300. http://dx.doi.org/10.1016/j.cytogfr.2011.11.006.
    10.1016/j.cytogfr.2011.11.006
  10. Pereira, Paulo NG; Dobreva, Mariya P; Graham, Liz; Huylebroeck, Danny; Lawson, Kirstie A; Zwijsen, AN; Pereira, P.N.; et al. "Amnion formation in the mouse embryo: the single amniochorionic fold model". BMC Developmental Biology 11 1 (2011): 48. http://dx.doi.org/10.1186/1471-213x-11-48.
    10.1186/1471-213x-11-48
  11. Dobreva, Mariya P.; Pereira, Paulo N. G.; Deprest, Jan; Zwijsen, An. "On the origin of amniotic stem cells: of mice and men". The International Journal of Developmental Biology 54 5 (2010): 761-777. http://dx.doi.org/10.1387/ijdb.092935md.
    10.1387/ijdb.092935md
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2013/10 Ccbe1: a secreted protein with cardiomyogenic potential 2nd Portuguese Society of Developmental Biology Meeting
Portuguese Society of Developmental Biology (Lisboa, Portugal)
2011/05 Antagonism of Nodal signaling by BMP/Smad5 prevents ectopic primitive streak formation in the mouse embryo ( doi: 10.1038/embor.2011.186 ) EMBO Workshop – Lineage commitments: emphasis on extraembryonic-embryonic interfaces
(Leuven, Belgium)
2010/09 BMP/Smad5 signaling antagonizes Nodal signaling: a mechanism to prevent ectopic primitive streak formation in the mouse embryo 8th International Conference on Bone Morphogenetic Proteins
(Leuven, Belgium)
2009/12 Nodal signaling is modulated by BMP signaling in a Smad5 dependent manner GABBA PhD Program 2009 annual Meeting
GABBA PhD Program (Porto, Portugal)
2009/11/27 Nodal signaling is modulated by BMP signaling in a Smad5 dependent manner IUAP-meeting
(Leuven, Belgium)
2009/06/09 Ectopic recapitulation of a hierarchy of signaling cascades induces an extraembryonic primitive streak in the Smad5 deficient mouse amnion VIB11 retreat
Vlaams Instituut voor Biotechnologie (Mol, Belgium)

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2013 Development of a Piggybac based direct reprogramming system for derivation of integration free induced pluripotent stem cells
(Thesis) Main arguer
 Dino Matias (Master)
Universidade do Algarve - Campus de Gambelas, Portugal
2013 Reprogramming of Mouse Fibroblast cells and characterization of mouse iPS cells
(Thesis) Arguer
 André Alves (Master)
Universidade do Algarve - Campus de Gambelas, Portugal

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2015/01 - 2016/02 Developmental Biology, practical course - 6 hours total Medicina (Licenciatura) Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2015/01 - 2016/02 Developmental Biology, practical course - 6 hours total ProRegeM program PhD students (Doutoramento) Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2013/09 - 2014/04 Developmental Biology, practical course - 8 hours total Ciências Biomédicas (Mestrado) Universidade do Algarve - Campus de Gambelas, Portugal
2013/09 - 2014/04 Stem Cell Biology to Biomedical Sciences, Theoretical course - 8 hours total Oncobiologia (Mestrado) Universidade do Algarve - Campus de Gambelas, Portugal
2013/09 - 2014/04 Developmental Biology, practical course - 8 hours total ProRegeM PhD program students (Doutoramento) Universidade do Algarve - Campus de Gambelas, Portugal

Mentoring / Tutoring

Topic Student name
2012/04 - 2016/02 Role of Ccbe1 during cardiac differentiation of mouse ESCs. Tiago Justo