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In September of 2018, I completed my PhD in Biochemistry at University of Aveiro (UA). My PhD was supported by a Grant from an European Research Council (ERC) project intitled: "IgY Technology: A Purification Platform using Ionic-Liquid-Based Aqueous Biphasic Systems". During my PhD, from January 2015 to March 2015, I was a trainee at Institut National des Sciences Appliquées de Lyon, France. From October 2018 to March 2019, I was a post-doctoral researcher involved in the same International Project from the ERC, at UA, now focused on the developed technologies scale-up. In October of 2018, I was a visiting researcher at Université de Reims Champagne Ardenne - Institut de Chimie Moléculaire de Reims, France, working on ionic liquids synthesis. From April 2019 to January 2022, I was a researcher involved in the development of new platforms for the purification of L-Asparaginase, an antileukemic biopharmaceutical of current high-cost. In June 2019, I was a visiting researcher at Université de Reims Champagne Ardenne, and from October to November 20219, I was a visiting researcher in School of Pharmaceutical Sciences, UNESP, Araraquara, Brazil. Since February 2022 I'm a researcher in ITQB-NOVA focused on heme homeostasis in human pathogens, namely on the enzymes involved in heme biosynthesis and acquisition pathways. Since 2014, I published 30 articles in international peer reviewed journals and 6 book chapters, demonstrating my commitment to science. Besides my publications, during my PhD an efficient technology to purify Immunoglobulin Y (IgY) was developed and an international patent (WO 2020/058937 A1) application was filled. With the aim to promote my research work over the world, I participated in several national/international meetings. During the past years, I was the supervisor of 9 BSc final projects and co-supervisor of 4 MSc theses, and collaborated in the supervision of 4 MSc theses and 1 BSc final project.
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Identification

Personal identification

Full name
Ana Mafalda Rodrigues Almeida Rocha

Citation names

  • Mafalda R. Almeida

Author identifiers

Ciência ID
8E16-D486-1960
ORCID iD
0000-0003-2101-8309
Scopus Author Id
56096309900

Email addresses

  • mafalda.almeida90@gmail.com (Personal)

Telephones

Mobile phone
  • 911885716 (Personal)

Addresses

  • ITQB-NOVA, 2780-157, Oeiras, Oeiras, Portugal (Professional)
  • Rua Prof. António Rainho, nº1, 1ºEsq., 2500-118, Caldas da Rainha, Caldas da Rainha, Portugal (Personal)

Websites

Knowledge fields

  • Engineering and Technology - Industrial Biotechnology
  • Natural sciences - Biological Sciences - Biochemistry
  • Natural sciences - Biological Sciences - Biochemistry
  • Natural sciences - Biological Sciences - Microbiology
  • Natural sciences - Biological Sciences - Molecular Biology

Languages

Language Speaking Reading Writing Listening Peer-review
English Intermediate (B1) Intermediate (B1) Intermediate (B1) Upper intermediate (B2) Intermediate (B1)
Portuguese (Mother tongue)
Education
Degree Classification
2018/10 - 2019/03
Concluded
 Research fellow (Pós-doutoramento)
Universidade de Aveiro, Portugal
2014/02/01 - 2018/09/21
Concluded
 Bioquímica (Doutoramento)
Major in Sem especialidade
Universidade de Aveiro, Portugal
"Development of purification platforms for Immunoglobulin Y using aqueous biphasic systems" (THESIS/DISSERTATION)
2017/02 - 2017/07
Concluded
 COHiTEC Program (Outros)
Universidade do Porto Porto Business School, Portugal
2015/01/08 - 2015/03/30
Concluded
 Centrifugal partition chromatography course (Outros)
Institut des Sciences Analytiques, France
2011 - 2013/07/11
Concluded
 Bioquímica (Mestrado)
Major in Área de especialização: Métodos Biomoleculares
Universidade de Aveiro, Portugal
"Purification of antibodies using aqueous-two phase systems" (THESIS/DISSERTATION)
2008 - 2011/09
Concluded
 Bioquímica (Licenciatura)
Universidade de Aveiro, Portugal
Affiliation

Science

Category
Host institution 		Employer
2022/02/23 - Current Researcher (Research) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2019/04/01 - 2022/01/31 Researcher (Research) Universidade de Aveiro, Portugal
Universidade de Aveiro CICECO, Portugal
2019/10/22 - 2019/11/21 Visiting Researcher (Research) Universidade Estadual Paulista Júlio de Mesquita Filho Câmpus de Araraquara Faculdade de Ciências Farmacêuticas, Brazil
Universidade Estadual Paulista Júlio de Mesquita Filho Câmpus de Araraquara Faculdade de Ciências Farmacêuticas, Brazil
2019/06/18 - 2019/06/27 Visiting Researcher (Research) Institut de Chimie Moléculaire de Reims, France
Institut de Chimie Moléculaire de Reims, France
2018/10 - 2019/03 Postdoc (Research) Universidade de Aveiro CICECO, Portugal
2018/10/09 - 2018/10/19 Visiting Researcher (Research) Institut de Chimie Moléculaire de Reims, France
Institut de Chimie Moléculaire de Reims, France
2014/02/01 - 2018/09/21 Research Trainee (Research) Universidade de Aveiro CICECO, Portugal
2015/01 - 2015/03 Visiting Researcher (Research) Institut National des Sciences Appliquées de Lyon, France
Projects

Grant

Designation Funders
2014/02/01 - 2018/09/20 IgY technology: a purification platform using ionic-liquid-based aqueous biphasic systems
ECR-2013-StG-337753
PhD Student Fellow
Universidade de Aveiro CICECO, Portugal
 European Research Council
Concluded

Contract

Designation Funders
2022/10/01 - Current Interaction of RIC with iron-sulfur biogenesis systems
PTDC/BIA-MIC/0268/2021
Researcher
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
Ongoing
2022/02/23 - 2022/09/30 Diversity and complexity of microbial multidomain oxygen and/or nitric oxide reductases flavodiiron enzymes from Clostridiales
PTDC/BIA-BQM/27959/2017
Researcher
Concluded
2019/04/01 - 2022/01/31 Development of sustainable nanomaterials for the purification of antileukemic drugs
POCI-01-0145-FEDER-031268
Researcher
Universidade de Aveiro, Portugal

Universidade do Porto Faculdade de Engenharia, Portugal

Universidade Estadual Paulista Júlio de Mesquita Filho Câmpus de Araraquara Faculdade de Ciências Farmacêuticas, Brazil
Fundação para a Ciência e a Tecnologia
Concluded

Other

Designation Funders
2018/06 - 2019/12/31 Extraction and purification of RuBisCo: from waste product to high-value functional protein
4318/40851YL
Researcher
Universidade de Aveiro CICECO, Portugal

Institut de Chimie Moléculaire de Reims, France
Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Book chapter
  1. João C. F. Nunes; Flávia F. Magalhães; Marília T. Araújo; Mafalda R. Almeida; Mara G. Freire; Ana P. M. Tavares. "Expansion of targeted drug-delivery systems using microbially sources biosurfactant". In Green Sustainable Process for Chemical and Environmental Engineering and Science, edited by Mohd Imran Ahamed; Charles Adetunji, 105-120. Elsevier, 2022.
    Published • 10.1016/b978-0-323-85146-6.00034-6
  2. Mafalda R. Almeida; João C. F. Nunes; Raquel O. Cristóvão; Joaquim L. Faria; Ana P. M. Tavares; Cláudia G. Silva; Mara G. Freire. "Carbon nanotubes for biomedical applications". In Materials Horizons: From Nature to Nanomaterials, 285-331. Springer Singapore, 2022.
    Published • 10.1007/978-981-16-7483-9_14
  3. Flávia F. Magalhães; João C. F. Nunes (FA1D-F3E2-FBA8); Marília T. Araújo; Ana M. Ferreira; Mafalda R. Almeida; Mara G. Freire; Ana P. M. Tavares (2A10-5072-A254). "Anti-cancer biosurfactants". In Microbial Biosurfactants: Preparation, Properties and Applications. Springer, 2021.
    Published • 10.1007/978-981-15-6607-3
  4. Mafalda R. Almeida; Márcia C. Neves; Sérgio Morales-Torres; Mara G. Freire; Joaquim L. Faria; Valéria C. Santos-Ebinuma; Cláudia G. Silva; Ana P. M. Tavares. "Biomedical related applications of functionalized nanomaterials". In Handbook of Functionalized Nanomaterials for Industrial Applications, edited by Chaudhery Mustansar Hussain. Elsevier, 2020.
    Published
  5. Mafalda R. Almeida; Ana M. Ferreira; João C. F. Nunes (FA1D-F3E2-FBA8); Ana P. M. Tavares (2A10-5072-A254). "Purification, characterization and clinical applications of therapeutic enzymes". In Research Advances in the Fungal World: Culture, Isolation, Identification, Classification, Characterization, Properties and Kinetics. Nova Science Publishers, 2020.
    Published
  6. Maria V. Quental; Mafalda R. Almeida; Joana Gomes; Judite Resende; Pedro Domingues; Mara G. Freire. "Imunoglobulina Y (IgY): uma alternativa promissora aos anticorpos de mamíferos". In Bioquímica e Bem-Estar, edited by Manuel António Coimbra. Portugal, 2017.
    Published
Conference poster
  1. Jordi Zamarreno Beas; Mafalda R. Almeida; Marco A. M. Videira; Val Karavaeva; Frederico M. Lourenço; Filipa Sousa; Lígia Saraiva. "Revealing heme b biosynthesis pathway in Campylobacter jejuni". Paper presented in Tetrapyrrole discussion group meeting, 2023.
  2. Ana F.C.S. Rufino; Mafalda R. Almeida; Mukesh Sharma; João A. P. Coutinho; Mara G. Freire. "Ionic liquid-based aqueous biphasic systems for extraction and purification of albumin from bovine serum". Paper presented in Jornadas CICECO 2022, 2022.
  3. Ana F.C.S Rufino; Mafalda R. Almeida; Mukesh Sharma; João A. P Coutinho; Mara G. Freire. "Separation of albumin from bovine serum applying ionic-liquid-based aqueous biphasic systems". Paper presented in BPP 2022, Biopartitiong & Purification Conference, 2022.
  4. João A. P. Coutinho; Mafalda R. Almeida; Filipe Ferreira; Pedro Domingues; Mara G. Freire. "Towards the purification of IgY from egg yolk by centrifugal partition chromatography". Paper presented in ISEC 2022, International solvent extraction conference, 2022.
  5. Mafalda R. Almeida; Bruno A. Salgueiro; Filipe Folgosa; Miguel Teixeira. "Characterization of Pseudogulbenkiana ferrooxidans and Photobacterium swingsii flavorubredoxins". Paper presented in Final Annual Meeting, Twin to illuminate metal in biology and biocatalysis through biospectroscopy, TIMB3, 2022.
  6. Ana P. M. Tavares (2A10-5072-A254); Mafalda R. Almeida; Raquel O. Cristóvão; Maria A. Barros; João C. F. Nunes; Joaquim L. Faria; Márcia C. Neves; et al. "Immobilization of L-asparaginase towards surface-modified carbon nanotubes". Paper presented in ISPPP 2021, 40th International Symposium on the Separation of Proteins, Peptides & Polynucleotides, 2021.
  7. João C. F. Nunes; Mafalda R. Almeida; Valéria C. Santos-Ebinuma; Márcia C. Neves; Mara G. Freire; Ana P. M. Tavares. "Sustainable lysis of Bacillus subtilis biomass to recover the biopharmaceutical L-asparaginase". Paper presented in MICROBIOTEC 21, Congress of Microbiology and Biotechnology 2021, 2021.
  8. Mafalda R. Almeida; Ana I. Valente; Ana M. Ferreira; Mara G. Freire; Ana P. M. Taes. "Extraction and purification of RuBisCO from residual biomass". Paper presented in RRB 2021, Renewable Resources & Biorefeneries Confererence, 2021.
  9. Ana F.C.S. Rufino; Mafalda R. Almeida; Mukesh Sharma; João A. P Coutinho; Mara G. Freire. "Ionic liquid-based aqueous biphasic systems for the pre-purification of bovine serum albumin". Paper presented in DCE 2021, Doctoral Congress in Engineering, 2021.
  10. Mafalda R. Almeida; Raquel O. Cristóvão; Maria A. Barros; João C. F. Nunes; Rui A.R. Boaventura; José M. Loureiro; Joaquim L. Faria; et al. "Immobilization of L-asparaginase towards surface-modified carbon nanotubes". Paper presented in Affinity 2021, 2021.
  11. Ana I. Valente; Ana M. Ferreira; Mara G. Freire; Mafalda R. Almeida; Aminou Mohamadou; Ana P. M. Tavares (2A10-5072-A254). "RuBisCOs' extraction and purification: from residual biomass to a value-added enzyme". Paper presented in Jornadas CICECO 2020 - THE FUTURE OF SCIENCE AND CICECO: what have we learned from the pandemic?, 2020.
  12. Daniel F. Castro; Valéria C. Santos-Ebinuma; Mara G. Freire; Mafalda R. Almeida; Ana P. M. Tavares (2A10-5072-A254). "Optimization of L-asparaginase production by Bacillus Subtilis". Paper presented in Jornadas CICECO 2020 - THE FUTURE OF SCIENCE AND CICECO: what have we learned from the pandemic?, 2020.
  13. Ana R. F. Carreira; Ana M. Ferreira; Mafalda R. Almeida; Joao A. P. Coutinho (8B1B-C80E-3C50); Tânia E. Sintra. "A selective journey: enantioselective biphasic systems for the resolution of propranolol". Paper presented in Jornadas CICECO 2020 - THE FUTURE OF SCIENCE AND CICECO: what have we learned from the pandemic?, 2020.
  14. João C. F. Nunes (FA1D-F3E2-FBA8); Rui M. F. Bento; Mafalda R. Almeida; Márcia C. Neves; Valéria C. Santos-Ebinuma; Ana P. M. Tavares (2A10-5072-A254); Mara G. Freire. "Improved immobilization of L-asparaginase on silica-based supported ionic liquids". Paper presented in Jornadas CICECO 2020 - THE FUTURE OF SCIENCE AND CICECO: what have we learned from the pandemic?, 2020.
  15. Rui M. F. Bento; Mafalda R. Almeida; Márcia C. Neves; Valéria C. Santos-Ebinuma; Mara G. Freire; Ana P. M. Tavares (2A10-5072-A254). "Enzyme adsorption on modified silica carriers". Paper presented in Jornadas CICECO 2020 - THE FUTURE OF SCIENCE AND CICECO: what have we learned from the pandemic?, 2020.
  16. João C. F. Nunes (FA1D-F3E2-FBA8); Raquel O. Cristóvão; M. Amélia Barros; Mafalda R. Almeida; Joaquim L. Faria; Maria J. Sampaio; Mara G. Freire; Ana P. M. Tavares (2A10-5072-A254); Cláudia G. Silva. "Using carbon nanotubes for antileukemic drugs purification". Paper presented in Microbiotec'19, 2019.
  17. João C. F. Nunes (FA1D-F3E2-FBA8); Margarida Rosmaninho; Margarida C. Ribeiro; Mafalda R. Almeida; Márcia C. Neves; Mara G. Freire; Ana P. M. Tavares (2A10-5072-A254). "Extraction of L-asparaginase through supported ionic liquid materials based on silica". Paper presented in Microbiotec'19, 2019.
  18. Rui M. F. Bento; Mafalda R. Almeida; Mara G. Freire; Ana P. M. Tavares (2A10-5072-A254). "Decolorization of dyes from textile effluents by laccase using ionic liquids". Paper presented in XXV Encontro Galego Portugués de Química, 2019.
  19. Sónia P. M. Ventura; João H. P. M. Santos; Mafalda R. Almeida; Ana C. R. V. Dias; Mara G. Freire; Joao A. P. Coutinho (8B1B-C80E-3C50). "Up-scale fractionation of phenolic compounds using centrifugal partition chromatography". Paper presented in ECAB5, 5th European Congress of Applied Biotechnology, 2019.
  20. Mafalda R. Almeida; Nunes, João C. F.; Raquel O. Cristóvão; M. Amélia Barros; Mara G. Freire; Valéria C. Santos-Ebinuma; Cláudia G. Silva; Ana P. M. Tavares. "Purification of antileukemic drugs using functionalized nanomaterials". Paper presented in BPP 22019, Bipartitiong & Purification Conference, 2019.
  21. Márcia C. Neves; Rui Bento; Mafalda R. Almeida; Mara G. Freire; Ana P. M. Tavares (2A10-5072-A254). "Micelar ionic liquid-based micellar systems in an integrated platform for the removal of indigo". Paper presented in RICI 8, 8th Iberian Meeting on Colloids and Interfaces, 2019.
  22. Mafalda R. Almeida; Leonor S. Castro; Patrícia Pereira; Luís Passarinha; Fani Sousa; Joao A. P. Coutinho (8B1B-C80E-3C50); Ana P. M. Tavares (2A10-5072-A254); Mara G. Freire; Augusto Q. Pedro. "Aqueous two-phase systems comprising ionic liquids for the extraction of recombinant proteins". Paper presented in XIV Annual CICS-UBI Symposium (Universidade da Beira Interior), 2019.
  23. Mafalda R. Almeida; Sandra C. Bernardo; Ana Isabel Valente; Mara G. Freire; Aminou Mohamadou; Ana P. M. Tavares (2A10-5072-A254). "Extraction of RuBisCO through glycine-betaine ionic liquids-based aqueous biphasic systems". Paper presented in Jornadas CICECO 2019, 2019.
  24. Mafalda R. Almeida; Margarida F. C. Faria; Mara G. Freire; Luísa M. P. Martinez; Cláudia G. Silva; Ana P. M. Tavares (2A10-5072-A254). "Purification of human serum IgG with carbon nanomaterials". Paper presented in Jornadas CICECO 2019, 2019.
  25. João C. F. Nunes (FA1D-F3E2-FBA8); Mafalda R. Almeida; Margarida Rosmaninho; Margarida Ribeiro; Márcia C. Neves; Mara G. Freire; Ana P. M. Tavares (2A10-5072-A254). "Antileukemic biopharmaceuticals purification using supported ionic liquid materials based on silica". Paper presented in Jornadas CICECO 2019, 2019.
  26. Rui M. F. Bento; Mafalda R. Almeida; Joao A. P. Coutinho (8B1B-C80E-3C50); Mara G. Freire; Ana P. M. Tavares (2A10-5072-A254). "Degradation of persistent pollutants using enzymatic micellar systems". Paper presented in Jornadas CICECO 2019, 2019.
  27. Leonor S. Castro; Mafalda R. Almeida; Patrícia Pereira; Luís Passarinha; Fani Sousa; Joao A. P. Coutinho (8B1B-C80E-3C50); Ana P. M. Tavares (2A10-5072-A254); Augusto Q. Pedro; Mara G. Freire. "Improving the purification of recombinant proteins by the use of ionic liquids as adjuvants in aqueous two-phase systems". Paper presented in Jornadas CICECO 2019, 2019.
  28. João C. F. Nunes; Mafalda R. Almeida; Margarida Rosmaninho; Margarida Ribeiro; Márcia C. Neves; Mara G. Freire; Ana P. M. Tavares. "Purification of antileukemic biopharmaceuticals using supported ionic liquid materials based on silica". Paper presented in 4th Meeting of Medicional Biotechnology, 2019.
  29. João C. F. Nunes; Margarida Rosmaninho; Margarida Ribeiro; Mafalda R. Almeida; Mara G. Freire; Ana P. M. Tavares (2A10-5072-A254). "Supported ionic liquid materials on silica for the purification of L-asparaginase". Paper presented in XII ENEBIOQ, XII Encontro Nacional de Estudantes de Bioquímica, 2019.
  30. Mara G. Freire; Mafalda R. Almeida; Ana Filipa M. Cláudio; Armando J. D. Silvestre; Erika S. Santos. "Salicornia crop in sustainable and highly saline agronomic systems as source of added-value compounds". Paper presented in 12th ESBES, 12th European Symposium on Biochemical Engineering Sciences, 2018.
  31. João H. P. M. Santos; Mafalda R. Almeida; Cláudia Martins; Ana C. R. V. Dias; Mara G. Freire; João A. P. Coutinho; Sónia P. M. Ventura. "Fractionation of phenolic compounds derived from lignin depolymerization by centrifugal partition chromatography". Paper presented in 12th ESBES, 12th European Symposium on Biochemical Engineering Sciences, 2018.
  32. Mafalda R. Almeida; Matheus M. Pereira; Joana Gomes; Ana F. C. S. Rufino; Marguerita E. Rosa; João A. P. Coutinho; Mara G. Freire. "Glycine-betaine ionic liquid analogues as novel phase-forming components of aqueous biphasic systems". Paper presented in Living science together, Jornadas CICECO 2018, 2018.
  33. Sónia P. M. Ventura; João H. P. M. Santos; Mafalda R. Almeida; Cláudia I. R. Martins; Ana C. R. V. Dias; Mara G. Freire; João A. P. Coutinho. "Centrifugal partition chromatography applied on the fractionation of phenolic compounds from lignin depolymerization". Paper presented in 2nd AGChem, 2nd Advances in Green Chemistry Conference, 2018.
  34. Mafalda R. Almeida; Judite Resende; Ana P. M. Tavares; Pedro Domingues; Mara G. Freire. "Aqueous biphasic systems (ABS) as an alternative platform to purify hen antibodies". Paper presented in ESIB2017, European Summit of Industrial Biotechnology 2017, 2017.
  35. João H. P. M. Santos; Cláudia Martins; Mafalda R. Almeida; Mara G. Freire; João A. P. Coutinho; Sónia P. M. Ventura. "Purification of phenolic compounds in continuous flow by centrifugal partition chromatography". Paper presented in BPP2017, Biopartitioning & Purification Conference 2017, 2017.
  36. Pankaj Bharmoria; Dibyendu Mondal; Matheus M. Pereira; Márcia C. Neves; Mafalda R. Almeida; Igor Bdikin; João A. P. Coutinho; Mara G. Freire. "Growth of functional protein fibrils from egg white proteome: effect of protein crowding". Paper presented in II Jornadas Nacionais de Caracterização de Materiais, 2017.
  37. Emanuel V. Capela; Mafalda R. Almeida; João A. P. Coutinho; Mara G. Freire. "Exploring ionic liquids for the development of a purification platform for therapeutic immunoglobulin Y (IgY) from egg yolk". Paper presented in ISPPP2016, International Symposium on the Separation of Proteins, Peptides and Polynucleotides 2016, 2016.
  38. Emanuel V. Capela; Mafalda R. Almeida; João A. P. Coutinho; Mara G. Freire. "Platform for the purification of immunoglobulin Y (IgY) from egg yolk using aqueous biphasic systems". Paper presented in ESBES2016, European Symposium on Biochemical Engineering Sciences 2016, 2016.
  39. Pankaj Bharmoria; Dibyendu Mondal; Matheus M. Pereira; Márcia C. Neves; Mafalda R. Almeida; Mara G. Freire. "Growth of functional protein fibrils from egg white proteome: effect of protein crowding". Paper presented in Energy: trends and future chalenges, Jornadas CICECO 2016, 2016.
  40. Emanuel V. Capela; Mafalda R. Almeida; João A. P. Coutinho; Mara G. Freire. "Purification of therapeutic immunoglobulin Y (IgY) from egg yolk using aqueous biphasic systems". Paper presented in IV ENEQUI, IV Encontro Nacional de Estudantes de Química, 2016.
  41. Emanuel V. Capela; Mafalda R. Almeida; João A. P. Coutinho; Mara G. Freire. "Purification of immunoglobulin Y (IgY) using Aqueous Biphasic Systems". Paper presented in 2nd EuGSC, 2nd EuCheMS Congress on Green and Sustainable Chemistry, 2015.
  42. Mafalda R. Almeida; Maria V. Quental; Kiki A. Kurnia; João A. P. Coutinho; Mara G. Freire. "Extraction of IgY using a new category of aqueous biphasic systems composed of two ionic liquids". Paper presented in ECAB 3, 3rd European Congress of Applied Biotechnology, 2015.
  43. Maria V. Quental; Mafalda R. Almeida; Kiki A. Kurnia; João A. P. Coutinho; Mara G. Freire. "Aqueous biphasic systems composed of two ionic liquids as novel extraction platforms". Paper presented in IMIL15, Iberomerican Meeting on Ionic Liquids, 2015.
  44. Mafalda R. Almeida; Mohamed Taha; Francisca A. e Silva; Pedro Domingues; Sónia P. M. Ventura; João A. P. Coutinho; Mara G. Freire. "Novel biocompatible and self-buffering ionic liquids for biopharmaceutical applications". Paper presented in BPP 2015, Biopartitioning & Purification Conference 2015, 2015.
  45. Mafalda R. Almeida; Helena Passos; Matheus M. Pereira; Álvaro S. Lima; João A. P. Coutinho; Mara G. Freire. "Aqueous biphasic systems with ionic liquids as additives to upgrade the extraction of three antioxidants". Paper presented in BPP 2015, Biopartitioning & Purification Conference 2015, 2015.
  46. Mafalda R. Almeida; Maria V. Quental; Mara G. Freire; João A. P. Coutinho. "Aqueous biphasic systems composed of two ionic liquids: a new plethora of separation platforms". Paper presented in Nineteenth Symposium on Thermophysical Properties, 2015.
  47. Joana Gomes; Judite Resende; Mafalda R. Almeida; Ana P. M. Tavares; Pedro Domingues; João A. P. Coutinho; Mara G. Freire. "Extraction of Immunoglobulin Y using aqueous biphasic systems". Paper presented in Nanotechnology-from the lab to the industry, Jornadas CICECO 2015, 2015.
  48. Isabel Boal-Palheiros; Tatiana S. M. Vaz; Mafalda R. Almeida; Mara G. Freire. "Novel aqueous biphasic systems composed of phosphonium-based ionic liquids and polyvinylpirrolidone". Paper presented in Nanotechnology-from the lab to the industry, Jornadas CICECO 2015, 2015.
  49. Mafalda R. Almeida; Helena Passos; Matheus M. Pereira; Álvaro S. Lima; João A. P. Coutinho; Mara G. Freire. "Remarkable extraction of antioxidants using ionic liquids as adjuvants in aqueous biphasic systems". Paper presented in Nanotechnology-from the lab to the industry, Jornadas CICECO 2015, 2015.
  50. Mafalda R. Almeida; Emanuel V. Capela; Helena Passos; João A.P. Coutinho; Mara G. Freire. "Addition of ionic liquids to tune the phases polarities of polymer-salt aqueous biphasic systems". Paper presented in ECTP2014, 20th European Conference on Thermophysical Properties, 2014.
  51. Mafalda R. Almeida; Ana Filipa M. Cláudio; Mara G. Freire; Erika S. Santos; Joana Pacheco. "Characterization of phenolic compounds from different species of halophytes from Reserva Natural do Sapal de Castro Marim e Vila Real de Santo António". Paper presented in IMMR’14, Internation Meeting on Marine Research’ 2014, 2014.
  52. Isabel Boal-Palheiros; Tatiana S. M. Vaz; Mafalda R. Almeida; Mara G. Freire. "Novel aqueous biphasic systems composed of phosphonium-based ionic liquids and polivinylpirrolidone". Paper presented in EUCHEM2014, Conference on Molten Salts and Ionic Liquids, 2014.
  53. Tatiana S. M. Vaz; Mafalda R. Almeida; Isabel Boal-Palheiros; Mara G. Freire. "Aqueous biphasic systems composed of phosphonium-based ionic liquids and polyvinylpyrrolidone". Paper presented in ILSEPT, 2nd International Conference on Ionic Liquids in Separation and Purification Technology, 2014.
  54. Mafalda R. Almeida; Emanuel V. Capela; Helena Passos; João A. P. Coutinho; Mara G. Freire. "Tailoring the phases polarities of polymer-salt aqueous biphasic systems by the addition of ionic liquids". Paper presented in ILSEPT, 2nd International Conference on Ionic Liquids in Separation and Purification Technology, 2014.
  55. Mafalda R. Almeida; Helena Passos; Álvaro S. Lima; João A. P. Coutinho; Mara G. Freire. "Extraction of antioxidants using aqueous biphasic systems with ionic liquids as adjuvants". Paper presented in EXIL Workshop 2014, 2014.
  56. Matheus M. Pereira; Rafaela A. P. Cruz; Mafalda R. Almeida; Mara G. Freire. "Ionic liquids as adjuvants in aqueous two-phase systems for the selective extraction of ovalbumin from egg white". Paper presented in MicroBiotec13, Portuguese Congress of Microbiology and Biotechnology' 2013, 2013.
  57. Mafalda R. Almeida; Helena Passos; Mara G. Freire. "Purification of immunoglobulin Y (IgY) using aqueous biphasic systems". Paper presented in MicroBiotec13, Portuguese Congress of Microbiology and Biotechnology' 2013, 2013.
  58. Mafalda R. Almeida; João A. P. Coutinho; Mara G. Freire. "Aqueous biphasic systems composed of polymers and salts: effect of ionic liquids through their phase diagrams". Paper presented in Summer School on Ionic Liquids, 2013.
  59. Mafalda R. Almeida; Matheus M. Pereira; Helena Passos; João A. P. Coutinho; Mara G. Freire. "Immunoglobulin Y (IgY): a purification platform using ionic-liquid-based aqueous biphasic systems". Paper presented in Research Day 2013, 2013.
Encyclopedia entry
  1. Liliana S. Silva; Frederico M. Lourenço; Mafalda R. Almeida; Lígia M. Saraiva. "Structural Basis of Escherichia coli YtfE Iron Donor Properties". In Encyclopedia of Inorganic and Bioinorganic Chemistry, 2023.
    Published
Journal article
  1. Jordi Zamarreno Beas; Marco A. M. Videira, ; Val Karavaeva; Frederico M. Lourenço; Mafalda R. Almeida; Filipa Sousa; Lígia M. Saraiva. "In Campylobacter jejuni, a new type of chaperone receives heme from ferrochelatase". Frontiers in Genetics 14 (2023): http://dx.doi.org/10.3389/fgene.2023.1199357.
    10.3389/fgene.2023.1199357
  2. João C. F. Nunes; Mafalda R. Almeida; Gabriela B. de Paiva; Danielle B. Pedrolli; Valéria C. Ebinuma-Santos; Márcia C. Neves; Mara G. Freire; Ana P. M. Tavares. "A flow-through strategy using supported ionic liquids for L-asparaginase purification". Separation and Purification Technology 315 (2023): 123718. http://dx.doi.org/10.1016/j.seppur.2023.123718.
    In press • 10.1016/j.seppur.2023.123718
  3. Liliana S O Silva; Frederico M. Lourenço; Mafalda R. Almeida; Saraiva, Ligia M. "Structural Basis of Escherichia coli YtfE Iron Donor Properties". Encyclopedia of Inorganic and Bioinorganic Chemistry (2023):
    Published
  4. Marguerita E. Rosa; Ana M. Ferreira; Catarina M. S. S. Neves; Mafalda R. Almeida; Rafael Barros; Ana C. Cristóvão; Ana C. A. Sousa; et al. "Valorisation of red beet waste: one-step extraction and separation of betalains and chlorophylls using thermoreversible aqueous biphasic systems". Green Chemistry 25 5 (2023): 1852-1864. http://dx.doi.org/10.1039/d2gc04480c.
    Published • 10.1039/d2gc04480c
  5. Mafalda R. Almeida; Rita A. M. Barros; Matheus M. Pereira; Daniel Castro; Joaquim L. Faria; Mara G. Freire; Cláudia G. Silva; Ana P.M.Tavares. "Multi-walled carbon nanotubes as a platform for Immunoglobulin G attachment". Chemical Engineering and Processing - Process Intensification 183 (2023): 109214. http://dx.doi.org/10.1016/j.cep.2022.109214.
    10.1016/j.cep.2022.109214
  6. Bojan Kopilovic; Ana I. Valente; Ana M. Ferreira; Mafalda R. Almeida; Ana P. M. Tavares; Mara G. Freire; Joao A. P. Coutinho. "Towards the sustainable extraction and purification of non-animal proteins from biomass using alternative solvents". RSC Sustainability 1 6 (2023): 1314-1331. http://dx.doi.org/10.1039/d3su00062a.
    10.1039/d3su00062a
  7. Mafalda R. Almeida; Filipe Ferreira; Pedro Domingues; João A. P. Coutinho; Mara G. Freire. "Towards the purification of IgY from egg yolk by centrifugal partition chromatography". Separation and Purification Technology 299 (2022): 121697. http://dx.doi.org/10.1016/j.seppur.2022.121697.
    10.1016/j.seppur.2022.121697
  8. Heitor B. S. Bento; Gabriela B. Paiva; Mafalda R. Almeida; Cláudia G. Silva; Pedro J. Carvalho; Ana P. M. Tavares; Danielle B. Pedrolli; Valéria C. Ebinuma-Santos. "Aliivibrio fischeri L-asparaginase production by engineered Bacillus subtilis: a potential new biopharmaceutical". Bioprocess and Biosystems Engineering 45 10 (2022): 1635-1644. http://dx.doi.org/10.1007/s00449-022-02769-x.
    10.1007/s00449-022-02769-x
  9. Mafalda R. Almeida; Ana F.C.S. Rufino; Diana C.V. Belchior; Pedro J. Carvalho; Mara G. Freire. "Characterization of cholinium-carboxylate-based aqueous biphasic systems". Fluid Phase Equilibria 558 (2022): 113458. http://dx.doi.org/10.1016/j.fluid.2022.113458.
    10.1016/j.fluid.2022.113458
  10. João C. F. Nunes; Mafalda R. Almeida; Rui M. F. Bento; Matheus M. Pereira; Valéria C. Santos-Ebinuma; Márcia C. Neves; Mara G. Freire; Ana P. M. Tavares (2A10-5072-A254). "Enhanced enzyme reuse through the bioconjugation of L-asparaginase and silica-based supported ionic liquid-like phase materials". Molecules 27 3 (2022): 929. http://dx.doi.org/10.3390/molecules27030929.
    10.3390/molecules27030929
  11. Ana F. C. S. Rufino; Mafalda R. Almeida; Mukesh Sharma; João A. P. Coutinho; Mara G. Freire. "Separation of albumin from bovine serum applying ionic-liquid-based aqueous biphasic systems". Applied Sciences 12 2 (2022): 707. http://dx.doi.org/10.3390/app12020707.
    10.3390/app12020707
  12. Ana I. Valente; Ana M. Ferreira; Mafalda R. Almeida; Aminou Mohamadou; Mara G. Freire; Ana P. M. Tavares. Corresponding author: Ana P. M. Tavares. "Efficient extraction of the RuBisCO enzyme from spinach leaves using aqueous solutions of biocompatible ionic liquids". Sustainable Chemistry 3 1 (2021): 1-18. http://dx.doi.org/10.3390/suschem3010001.
    10.3390/suschem3010001
  13. Mafalda R. Almeida; Raquel O. Cristóvão; Maria A. Barros; João C. F. Nunes; Rui A. R. Boaventura; José M. Loureiro; Joaquim L. Faria; et al. Corresponding author: Cláudia G. Silva. "Superior operational stability of immobilized l-asparaginase over surface-modified carbon nanotubes". Scientific Reports 11 1 (2021): http://dx.doi.org/10.1038/s41598-021-00841-2.
    Published • 10.1038/s41598-021-00841-2
  14. Castro, Daniel; Marques, Ana Sofia C.; Almeida, Mafalda R.; de Paiva, Gabriela B.; Bento, Heitor B. S.; Pedrolli, Danielle B.; Freire, Mara G.; Tavares, Ana P. M.; Santos-Ebinuma, Valéria C.. "L-asparaginase production review: bioprocess design and biochemical characteristics". Applied Microbiology and Biotechnology 105 11 (2021): 4515-4534. http://dx.doi.org/10.1007/s00253-021-11359-y.
    10.1007/s00253-021-11359-y
  15. João C. F. Nunes; Mafalda R. Almeida; Joaquim L. Faria; Cláudia G. Silva; Neves, Márcia C.; Mara G. Freire; Ana P. M. Tavares (2A10-5072-A254). "Overview on protein extraction and purification using ionic-liquid-based processes". Journal of Solution Chemistry (2021): http://dx.doi.org/10.1007/s10953-021-01062-x.
    10.1007/s10953-021-01062-x
  16. Álvaro Silva Lima; Bruno Sales de Oliveira; Selesa Vanessa Shabudin; Mafalda R. Almeida; Mara G. Freire; Katharina Bica. "Purification of anthocyanins from grape pomace by centrifugal partition chromatography". Journal of Molecular Liquids 326 (2021): 115324. http://dx.doi.org/10.1016/j.molliq.2021.115324.
    10.1016/j.molliq.2021.115324
  17. Bruna P. Soares; João H.P.M. Santos; Margarida Martins; Mafalda R. Almeida; Nathalia V. Santos; Mara G. Freire; Valéria C. Santos-Ebinuma; et al. "Purification of green fluorescent protein using fast centrifugal partition chromatography". Separation and Purification Technology 257 (2021): 117648. http://dx.doi.org/10.1016/j.seppur.2020.117648.
    10.1016/j.seppur.2020.117648
  18. Ana R.F. Carreira; Ana M. Ferreira; Mafalda R. Almeida; João A.P. Coutinho; Tânia E. Sintra. "Propranolol resolution using enantioselective biphasic systems". Separation and Purification Technology 254 (2021): 117682. http://dx.doi.org/10.1016/j.seppur.2020.117682.
    10.1016/j.seppur.2020.117682
  19. Daniela Millan; Mafalda R. Almeida; Ana Filipa Rufino; Joao A. P. Coutinho; Mara G. Freire. "Nucleophilic degradation of Diazinon in thermoreversible polymer-polymer aqueous biphasic systems". Physical Chemistry Chemical Physics (2021): http://dx.doi.org/10.1039/d0cp06086k.
    10.1039/d0cp06086k
  20. Raquel O. Cristóvão; Mafalda R. Almeida; Maria A. Barros; João C. F. Nunes (FA1D-F3E2-FBA8); Rui A.R. Boaventura; José M. Loureiro; Joaquim L. Faria; et al. "Development and characterization of a novel l-asparaginase/MWCNT nanobioconjugate". RSC Advances 10 52 (2020): 31205-31213. http://dx.doi.org/10.1039/d0ra05534d.
    10.1039/d0ra05534d
  21. Pankaj Bharmoria; Dibyendu Mondal; Matheus M. Pereira; Márcia C. Neves; Mafalda R. Almeida; Maria C. Gomes; João F. Mano; et al. "Instantaneous fibrillation of egg white proteome with ionic liquid and macromolecular crowding". Communications Materials 1 1 (2020): http://dx.doi.org/10.1038/s43246-020-0035-0.
    10.1038/s43246-020-0035-0
  22. Aleksandra Dimitrijevic; Ana P. M. Tavares (2A10-5072-A254); Mafalda R. Almeida; Milan Vrane; Ana C. A. Sousa; Ana C. Cristóvão; Tatjana Trtic-Petrovic; Slobodan Gad¿uric; Mara G. Freire. "Valorization of expired energy drinks by designed and integrated ionic liquid-based aqueous biphasic systems". ACS Sustainable Chemistry & Engineering 8 14 (2020): 5683-5692. http://dx.doi.org/10.1021/acssuschemeng.0c00429.
    10.1021/acssuschemeng.0c00429
  23. Rui M. F. Bento; Mafalda R. Almeida; Pankaj Bharmoria; Mara G. Freire; Ana P. M. Tavares (2A10-5072-A254). "Improvements in the enzymatic degradation of textile dyes using ionic-liquid-based surfactants". Separation and Purification Technology 235 (2020): 116191. http://dx.doi.org/10.1016/j.seppur.2019.116191.
    10.1016/j.seppur.2019.116191
  24. Flávia F. Magalhães; Mafalda R. Almeida; Sofia F. Soares (6D19-4755-BF06); Tito Trindade; Mara G. Freire; Ana Luísa Daniel-da-Silva; Ana P. M. Tavares (2A10-5072-A254). "Recovery of immunoglobulin G from rabbit serum using ¿-carrageenan-modified hybrid magnetic nanoparticles". International Journal of Biological Macromolecules (2020): http://dx.doi.org/10.1016/j.ijbiomac.2020.02.135.
    Published • 10.1016/j.ijbiomac.2020.02.135
  25. Mafalda R. Almeida; Diana C. V. Belchior; Pedro J. Carvalho; Mara G. Freire. "Liquid-liquid equilibrium and extraction performance of aqueous biphasic systems composed of water, cholinium carboxylate ionic liquids and K2CO3". Journal of Chemical & Engineering Data (2019): http://dx.doi.org/10.1021/acs.jced.9b00452.
    Published • 10.1021/acs.jced.9b00452
  26. Diana C. V. Belchior; Mafalda R. Almeida; Tânia E. Sintra; Sónia P. M. Ventura; Iola F. Duarte; Mara G. Freire. "Odd-even effect in the formation and extraction performance of ionic-liquid-based aqueous biphasic systems". Industrial & Engineering Chemistry Research (2019): http://dx.doi.org/10.1021/acs.iecr.9b00663.
    Published • 10.1021/acs.iecr.9b00663
  27. João H. P. M. Santos; Ana M. Ferreira; Mafalda R. Almeida; Paula S. G. N. Quinteiro; Ana C. R. V. Dias; Joao A. P. Coutinho (8B1B-C80E-3C50); Mara G. Freire; Carlota O. Rangel-Yagui; Sónia P. M. Ventura. "Continuous separation of cytochrome-c PEGylated conjugates by fast centrifugal partition chromatography". Green Chemistry (2019): http://dx.doi.org/10.1039/c9gc01063g.
    Published • 10.1039/c9gc01063g
  28. João H. P. M. Santos; Mafalda R. Almeida; Cáudia I. R. Martins; Ana C. R. V. Dias; Mara G. Freire; Joao A. P. Coutinho; Sónia P. M. Ventura. "Separation of phenolic compounds by centrifugal partition chromatography". Green Chemistry 20 8 (2018): 1906-1916. http://www.scopus.com/inward/record.url?eid=2-s2.0-85045949682&partnerID=MN8TOARS.
    Published • 10.1039/c8gc00179k
  29. Matheus M. Pereira; Mafalda R. Almeida; Joana M. Gomes; Ana F. C. S. Rufino; Marguerita E. Rosa; Joao A. P. Coutinho (8B1B-C80E-3C50); Aminou Mohamadou; Mara G. Freire. "Glycine-betaine ionic liquid analogues as novel phase-forming components of aqueous biphasic systems". Biotechnology Progress 34 5 (2018): 1205-1212. http://www.scopus.com/inward/record.url?eid=2-s2.0-85053194986&partnerID=MN8TOARS.
    Published • 10.1002/btpr.2685
  30. Matheus M. Pereira; Rafaela A. P. Cruz; Mafalda R. Almeida; Álvaro S. Lima; Joao A. P. Coutinho (8B1B-C80E-3C50); Mara G. Freire. "Single-step purification of ovalbumin from egg white using aqueous biphasic systems". Process Biochemistry 51 6 (2016): 781-791. http://www.scopus.com/inward/record.url?eid=2-s2.0-84978321056&partnerID=MN8TOARS.
    Published • 10.1016/j.procbio.2016.03.002
  31. Mohamed Taha; Mafalda R. Almeida; Francica A. e Silva; Pedro Domingues; Sónia P. M. Ventura; Joao A. P. Coutinho (8B1B-C80E-3C50); Mara G. Freire. "Novel biocompatible and self-buffering ionic liquids for biopharmaceutical applications". Chemistry - A European Journal 21 12 (2015): 4781-4788. http://www.scopus.com/inward/record.url?eid=2-s2.0-84924062386&partnerID=MN8TOARS.
    Published • 10.1002/chem.201405693
  32. Mafalda R. Almeida; Helena Passos; Matheus M. Pereira; Álvaro S. Lima; Joao A. P. Coutinho (8B1B-C80E-3C50); Mara G. Freire. "Ionic liquids as additives to enhance the extraction of antioxidants in aqueous two-phase systems". Separation and Purification Technology 128 (2014): 1-10. http://www.scopus.com/inward/record.url?eid=2-s2.0-84897480798&partnerID=MN8TOARS.
    Published • 10.1016/j.seppur.2014.03.004
Newsletter article
  1. Mafalda R. Almeida. "Publication | Purification of green fluorescent protein using fast centrifugal partition chromatography", UAveiro Research, 2021, https://mailchi.mp/7524680bc85a/uaveiro-research-newsletter-234?e=1ea214807b.
  2. Mafalda R. Almeida. "Publication | Recovery of immunoglobulin G from rabbit serum using k-carrageenan-modified hybrid magnetic nanoparticles", UAveiro Research, 2020, https://mailchi.mp/a575adaa7157/uaveiro-research-newsletter-199?e=1ea214807b.
  3. Mafalda R. Almeida. "Publication | Improvements in the enzymatic degradation of textile dyes using ionic-liquid-based surfactants", UAveiro Research, 2020, https://mailchi.mp/035941664835/uaveiro-research-newsletter-193?e=ccad0147cd.
Thesis / Dissertation
  1. Mafalda R. Almeida. "Development of purification platforms for immunoglobulin Y using aqueous biphasic systems". PhD, Universidade de Aveiro CICECO, 2018.
  2. Mafalda R. Almeida. "Purification of antibodies using aqueous two-phase systems". Master, Universidade de Aveiro CICECO, 2013.

Intellectual property

Patent
  1. Mafalda R. Almeida; Judite Resende; Ana P. M. Tavares; Pedro Miguel Dimas Neves Domingues; Mara G. Freire. 2020. "Purification of Immunoglobulin Y and uses thereof".
    Pending
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2022/06 Enhanced enzyme reuse through ASNase SILs bioconjugates EUCHEMSIL 2022, 28th EUCHEM Conference on Molten Salts and Ionic Liquids
(Patras, Greece)
2022/05 Extraction of RuBisCO from spinach leaves using aqueous solutions of biocompatible ionic liquids ISGC 2022, International Symposium on Green Chemistry
(La Rochelle, France)
2021/11/19 ELISA- Enzyme linked immunosorbent assays Microbial Biotechnology class
Universidade de Aveiro (Aveiro, Portugal)
2021/11 Purification of L-asparaginase produced by Bacillus subtilis using silica-based supported ionic liquids NEQConSCIENCE Day “Biotech and Chem Edition"
Universidade de Aveiro (Aveiro, Portugal)
2021/11 Purification of L-asparaginase produced by Bacillus subtilis using silica-based supported ionic liquids Science & Technology Week
Health Sciences Research Center of the University of Beira Interior (Covilhã, Portugal)
2021/11 Purification of antileukemic drugs through silica-based supported ionic liquids ISPPP 2021, 40th International Symposium on the Separation of Proteins, Peptides & Polynucleotides
(Porto, Portugal)
2021/09 Purification of L-asparaginase produced by Bacillus subtilis using silica-based supported ionic liquids 3rd NanoPurAsp Mini Symposium
2021/03 Supported ionic liquid materials for L-asparaginase immobilization 14º Encontro de Química Física
2019/11 Extraction of RuBisCO using aqueous biphasic systems composed of analogues of glycine-betaine ionic liquids BPP 2019, Bipartitiong & Purification Conference
(Guarujá, Brazil)
2019/11 Development of sustainable nanomaterials for the purification of antileukemic drugs 1º Seminário de Cooperação entre as Universidades de Aveiro e São Paulo.
Universidade de São Paulo (São Paulo, Brazil)
2019/11 Continuous separation of PEGylated proteins by fast centrifugal partition chromatography BPP 2019, Bipartitiong & Purification Conference
(Guarujá, Brazil)
2019/11 L-Asparaginase recovery through supported ionic liquid materials based on silica XXV Encontro Galego Portugués de Química, Santiago de Compostela
(Santiago de Compostela, Spain)
2019/09 Carbon nanomaterials for the purification of antileukemic drugs NANOMAT2019, International Functional Nanomaterials and Nanodevices Conference 2019
(Prague, Czech Republic)
2019/09 Downstream processing of recombinant proteins using alternative purification platforms ILSEPT 2019, 4th International Conference on Ionic Liquids in Separation and Purification Technology
(Sitges, Spain)
2019/09 Aqueous biphasic systems applied on the purification of recombinant green fluorescent protein up-scaled by centrifugal partition chromatography ILSEPT 2019, 4th International Conference on Ionic Liquids in Separation and Purification Technology
(Sitges, Spain)
2019/09 Development of sustainable nanomaterials for the purification of antileukemic drugs ECAB5, 5th European Congress of Applied Biotechnology
(Florence, Italy)
2019/06 Bioprocessing of recombinant proteins using alternative purification platforms Biotec Vigo 2019, Congreso Nacional de Biotecnología 2019
(Vigo, Spain)
2019/06 Tailoring carbon nanotubes surface chemistry for the purification of antileukemic drugs DCE 2019, 3rd Doctoral Congress in Engineering
Faculdade de Engenharia da Universidade do Porto (Porto, Portugal)
2018/09 Green fluorescent protein purification using centrifugal partition chromatography 12th ESBES, 12th European Symposium on Biochemical Engineering Sciences
(Lisbon, Portugal)
2018/04 Extraction of Green fluorescent protein and its purification using centrifugal partition chromatography 2nd AGChem, 2nd Advances in Green Chemistry Conference
(Poznan, Poland)
2017/11 Aqueous biphasic systems (ABS) as an alternative platform to purify hen antibodies ESIB 2017, European Summit of Industrial Biotechnology 2017
(Graz, Austria)
2017/11 Purification of hen immunoglobulins (IgY) using liquid-liquid centrifugal partitioning chromatography (CPC) ABC2, Anything But Conventional Chromatography 2017
(Lisbon, Portugal)
2017/11 Application of bio-based ionic liquids in aqueous biphasic systems to extract value-added compounds from expired energetic drinks ABC2, Anything But Conventional Chromatography 2017
(Lisbon, Portugal)
2017/09 Purification of phenolic compounds in continuous flow by centrifugal partition chromatography BPP2017, Biopartitioning & Purification Conference 2017
(Copenhagen, Denmark)
2016/11 Exploring ionic liquids for the development of a purification platform for therapeutic immunoglobulin Y (IgY) from egg yolk XXIIELGQ, XXII Encontro Luso-Galego de Química
(Bragança, Portugal)
2016/05 Addition of ionic liquids to tune the phases polarities of polymer-salt aqueous biphasic systems PATh Spring Workshop
(Ílhavo, Portugal)
2016/05 Purification of IgY using polymer-based aqueous biphasic systems combined with centrifugal partitioning chromatography PATh Spring Workshop
(Ílhavo, Portugal)
2016/05 Aqueous biphasic systems comprising two ionic liquids aiming at the development of improved separation techniques PATh Spring Workshop
(Ílhavo, Portugal)
2015/09 Purification of hen antibodies using aqueous biphasic systems combined with centrifugal partitioning chromatography ECAB 3, 3rd European Congress of Applied Biotechnology
(Nice, France)
2015/05 Novel aqueous biphasic systems composed of two ionic liquids ISGC 2015, 3rd International Symposium on Green Chemistry
(La Rochelle, France)
2014/11 Extaction and identification of added-value compounds from different species of halophytes from Reserva Natural de Sapal de Castro Marim e Vila Real de Santo António Seminar III Sustainable Growing of halophytes
(Castro Marim, Portugal)
2014/07 Ionic liquids as additives to improve the extraction of antioxidants in aqueous biphasic systems ILSEPT, 2nd International Conference on Ionic Liquids in Separation and Purification Technology
(Toronto, Canada)
2013/12 Purification of Immunoglobulin Y (IgY) using aqueous biphasic systems MicroBiotec13, Portuguese Congress of Microbiology and Biotechnology' 2013
(Aveiro, Portugal)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2022/03 - 2022/12/16 Antileukemic biopharmaceuticals production and purification using nanomaterials
Co-supervisor
 Engenharia Química (Master)
Universidade de Aveiro, Portugal
2021/09 - 2022/12 Produção e purificação de L-asparginase utilizando líquidos iónicos suportados
Supervisor
 Biotecnologia (Master)
Universidade de Aveiro, Portugal
2022/02 - 2022/07 Purificação da L-asparaginase utilizando líquidos iónicos suportados
Supervisor
 Biotecnologia (Degree)
Universidade de Aveiro, Portugal
2021/02 - 2021/07 Líquidos iónicos suportados em sílica para a extração e purificação da L-asparaginase
Co-supervisor
 Biotecnologia (Degree)
Universidade de Aveiro, Portugal
2021/02 - 2021/07 Extração e purificação da L-asparaginase utilizando líquidos iónicos suportados em sílica
Supervisor
 Biotecnologia (Degree)
Universidade de Aveiro, Portugal
2021/02 - 2021/07 Otimização da produção de L-asparaginase por Bacillus subtillis
Supervisor
 Biotecnologia (Degree)
Universidade de Aveiro, Portugal
2019/09 - 2020/12/17 RuBisCO extraction and purification: from residual biomass to value added protein
Co-supervisor
 Biotecnologia (Master)
Universidade de Aveiro, Portugal
2019/09/18 - 2020/12 Optimization of L-asparaginase production by Bacillus Subtilis
Co-supervisor
 Biotecnologia (Master)
Universidade de Aveiro, Portugal
2020/02 - 2020/07 Otimização da produção de L-asparaginase por Bacillus Subtillis
Supervisor
 Biotecnologia (Degree)
Universidade de Aveiro, Portugal
2019/02 - 2020/07 Extração de biomoléculas utilizando sistemas aquosos bifásicos
Co-supervisor
 Biotecnologia (Degree)
Universidade de Aveiro, Portugal
2019/02 - 2019/07 Purification of human serum IgG with functionalized carbon nanomaterials
Co-supervisor
 Bioquímica (Degree)
Universidade de Aveiro, Portugal
2019/02 - 2019/07 Supported ionic liquids for the extraction and purification of L-asparaginase
Supervisor
 Biotecnologia (Degree)
Universidade de Aveiro, Portugal
2019/02 - 2019/07 Carbon nanomaterials for the extraction and purification of L-asparaginase
Supervisor
 Biotecnologia (Degree)
Universidade de Aveiro, Portugal

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2021/09 - 2021/10 Co-organizer of 3rd NanoPurAsp Mini Symposium - Development of sustainable nanomaterials for the purification of antileukemic drugs (2021/10)
Symposium
 Universidade Estadual Paulista Júlio de Mesquita Filho Câmpus de Araraquara Faculdade de Ciências Farmacêuticas, Brazil
2020/10/01 - 2020/10/10 Co-organizer of Mini Symposium - Development of sustainable nanomaterials for the purification of antileukemic drugs within the 2nd year of the NanoPurAsp project (2020/11/09 - 2020/11/10)
Symposium (Co-organisor)
 Universidade de Aveiro, Portugal
2014/08 - 2014/09 Co-organizer of 20th European Conference on Thermophysical Properties (ECTP 2014) (2014/08/31 - 2014/09/04)
Conference (Other)
 Universidade do Porto Faculdade de Ciências, Portugal

Universidade de Aveiro CICECO, Portugal

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2023/04/26 - 2023/04/27 Participation in Tetrapyrrole Discussion Group Meeting. Poster presentation.
Meeting
 Tetrapyrrole Discussion Group Meeting
University of Kent, United Kingdom
2023/02/10 - 2023/02/11 Participation in 2nd Symposium on Alzheimers Disease: An Update on Pathology and Therapeutics
Symposium
 2nd Symposium on Alzheimer’s Disease: An Update on Pathology and Therapeutics
Universidade do Porto Faculdade de Engenharia, Portugal
2023/02/08 - 2023/02/08 Participation in LS4FUTURE - 1st General Meeting
Meeting
 LS4FUTURE - 1st General Meeting
2022/11/18 - 2022/11/18 Participation in CoLife Postdoc Day
Other
 CoLife Postdoc Day
Instituto Gulbenkian de Ciência, Portugal
2022/10/14 - 2022/10/14 Participation in V International Conference NOVAhealth Chronic Disease and Infection
Conference
 V International Conference NOVAhealth Chronic Disease and Infection
Universidade Nova de Lisboa, Portugal
2022/07 - 2022/07 Participation in the Final Annual Meeting of Twin to illuminate metal in biology and biocatalysis through biospectroscopy. Poster presentation.
Meeting
 Final Annual Meeting of Twin to illuminate metal in biology and biocatalysis through biospectroscopy
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2021/11 - 2021/11 Participation in NEQConSCIENCE Day Biotech and Chem Edition, with an invited oral presentation
Workshop
 NEQConSCIENCE Day
Universidade de Aveiro, Portugal
2021/11 - 2021/11 Participation in Science & Technology Week, from Health Sciences Research Center of the University of Beira Interior, with an invited oral presentation
Workshop
 Science & Technology Week
Universidade da Beira Interior, Portugal
2021/11 - 2021/11 Participation in the 40th International Symposium on the Purification of Proteins, Peptides and Polynucleotides (ISPPP 2021). Both poster and oral presentations.
Congress
Universidade da Beira Interior, Portugal
2021/10/14 - 2021/10/16 Participation in TechDays 2021, Aveiro, Portugal. In this event I show the work that I developed under the NanoPurAsp Project
Exhibition
 TechDays 2021
Universidade de Aveiro, Portugal
2021/09 - 2021/09 Participation in 3rd NanoPurAsp Mini Symposium - Development of sustainable nanomaterials for the purification of antileukemic drugs, with an invited oral presentation
Symposium
 3rd NanoPurAsp Mini Symposium
Universidade Estadual Paulista Júlio de Mesquita Filho Câmpus de Araraquara Faculdade de Ciências Farmacêuticas, Brazil
2020/11/09 - 2020/11/10 Participation in Mini Symposium - Development of sustainable nanomaterials for the purification of antileukemic drugs
Symposium
 Mini Symposium - Development of sustainable nanomaterials for the purification of antileukemic drugs
Universidade de Aveiro, Portugal
2020/09/21 - 2020/09/21 Participation in PATh/IonCytDevice Workshop: A Technological Perspective on Cancer: from Diagnosis and Treatment to Environmental Fate and Remediation
Workshop
 PATh/IonCytDevice Workshop-A Technological Perspective on Cancer: from Diagnosis and Treatment to Environmental Fate and Remediation
Universidade de Aveiro, Portugal
2019/11/11 - 2019/11/13 Participation in BPP 2019 Biopartitioning & Purification Conference. Both poster and oral presentations. BPP 2019 Biopartitioning & Purification Conference
2019/11/08 - 2019/11/08 Participation in 1º Seminário de Cooperação entre Universidades de Aveiro e São Paulo, with an invited oral presentation.
Meeting
 1º Seminário de Cooperação entre Universidades de Aveiro e São Paulo
Universidade de São Paulo, Brazil
2019/10/10 - 2019/10/12 Participation in TechDays 2019, Aveiro, Portugal. In this event I show the work that I developed under the NanoPurAsp Project
Exhibition
 TechDays 2019
2019/09/15 - 2019/09/19 Participation in 5th European Congress of Applied Biotechnology - ECAB5. Poster presentation.
Conference
 5th European Congress of Applied Biotechnology - ECAB5
Associazione Italiana Di Ingegneria Chimica, Italy
2019/06/11 - 2019/06/12 Participation in Jornadas CICECO 2019: Where Science meets Society
Conference
 ornadas CICECO 2019: Where Science meets Society
Universidade de Aveiro CICECO, Portugal
2019/05/17 - 2019/05/17 Participation in the 4th Meeting on Medicinal Biotechnology. This event is focus on Red Biotechnology (Health Biotechnology), and intends to present and disseminate relevant work done in this field.
Meeting
 4th Meeting on Medicinal Biotechnology
Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
2019/04/11 - 2019/04/11 Participation in PAth Spring Workshop: Deeping in the Eutectic Mixtures & Polymers
Workshop
 PAth Spring Workshop
Universidade de Aveiro CICECO, Portugal
2018/06/11 - 2018/06/12 Participation in Jornadas CICECO 2018
Meeting
 Jornadas CICECO 2018 - living science together
Universidade de Aveiro CICECO, Portugal
2018/03/22 - 2018/03/24 Participation in UA Open Campus 2018. In this event I show the work that I was developing in my PhD regarding the purification of antibodies from egg yolk.
Exhibition
 UA Open Campus 2018
Universidade de Aveiro, Portugal
2017/11/22 - 2017/11/24 Participation in Anything But Conventional Chromatography 2017 (ABC2). Oral presentations.
Congress
 ABC2 - Anything But Conventional Chromatography
European Society of Biochemical Engineering Sciences, Germany
2017/11/14 - 2017/11/16 Participation in European Summit of Industrial Biotechnology 2017 (ESIB2017). Both oral and poster presentations.
Congress
 ESIB 2017 - European Summit of Industrial Biotechnology 2017
Austrian Centre of Industrial Biotechnology, Austria
2017/10/12 - 2017/10/14 Participation in TechDays 2017, Aveiro, Portugal. In this event I show the work that I was developing in my PhD regarding the purification of antibodies from egg yolk.
Exhibition
 TechDays2017
Universidade de Aveiro, Portugal
2017/06/08 - 2017/06/08 Participartion in the 2nd edition of PATh Spring Workshop.
Workshop
 PATh Spring Workshop
Universidade de Aveiro CICECO, Portugal
2016/06/08 - 2016/06/09 Participation in Jornadas CICECO 2016. Poster presentation.
Meeting
 nergy: trends and future chalenges - Jornadas CICECO 2016
Universidade de Aveiro CICECO, Portugal
2016/05/09 - 2016/05/09 Participation in Path Spring Workshop. Two oral presentations.
Workshop
 PATh Spring Workshop
Universidade de Aveiro CICECO, Portugal
2016/02/10 - 2016/02/11 Participation in a chromatography seminar.
Seminar
 Chromatography seminar
TECNOCROMA, Portugal
2015/09/27 - 2015/10/01 Participation in the 3rd European Congress of Applied Biotechnology (ECAB 3). Both poster and oral presentations.
Congress
 ECAB 3 - 3rd European Congress of Applied Biotechnology
European Federation of Chemical Engineering, France

European Society of Biochemical Engineering Sciences, Germany
2015/06/07 - 2015/06/10 Participation in Biopartitioning & Purification Conference 2015 (BPP 2015). Poster presentation.
Congress
 BPP 2015 - Biopartitioning & Purification Conference 2015
Austrian Centre of Industrial Biotechnology, Austria
2015/04/14 - 2015/04/15 Participation in Jornadas CICECO 2015. Poster presentation.
Meeting
 Nanotechnology-from the lab to the industry, Jornadas CICECO 2015
Universidade de Aveiro CICECO, Portugal
2014/08/31 - 2014/09/04 Participartion in the 20th European Conference on Thermophysical Properties (ECTP 2014). Poster presentation.
Conference
 ECTP 2014 - 20th European Conference on Thermophysical Properties
Universidade do Porto Faculdade de Ciências, Portugal

Universidade de Aveiro CICECO, Portugal
2014/06/29 - 2014/07/02 Participation in the 2nd International Conference on Ionic Liquids in Separation and Purification Technology (ILSEPT). Both poster and oral presentations.
Congress
 ILSEPT 2014, 2nd International Conference on Ionic Liquids in Separation and Purification Technology
Elsevier BV, Netherlands
2014/04/24 - 2014/04/26 Participation in Liquid/liquid extraction by use of Ionic Liquids workshop. Poster presentation.
Workshop
 Liquid/liquid extraction by use of Ionic Liquids workshop
EXIL - EXchange on Ionic Liquids, Belgium
2013/12/06 - 2013/12/08 Participation in Portuguese Congress of Microbiology and Biotechnology 2013 (MicroBiotec'13). Both poster and oral presentation.
Congress
 MicroBiotec'13, Portuguese Congress of Microbiology and Biotechnology 2013,
Portuguese Society of Microbiology, Portugal
2013/06/09 - 2013/06/12 Participation in "Summer School on Ionic Liquids". Poster presentation.
Conference
 Summer School on Ionic Liquids
La Red Gallega de Líquidos Iónicos, Spain
2013/06 - 2013/06 Participation in Research Day 2013. Poster presentation.
Meeting
 Research Day 2013

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2023/11/26 Specific Avian Antibodies, Immunoglobulin Y (IgY), as Biopharmaceuticals to Tackle Multirresistent Bacteria
(Thesis) Main arguer
 Débora Sofia Tavares de Sousa (Master)
Universidade de Aveiro, Portugal
2022/12/16 Purification of immunoglobulin G-based biopharmaceuticals using supported ionic liquids
(Thesis) Main arguer
 Mariana Meireles e Castro (Master)
Universidade de Aveiro, Portugal
2022/12/16 Produção e purificação de biofármacos anti-leucémicos
Supervisor
 Tatiana Domingues Ferreira (Master)
Universidade de Aveiro, Portugal
2022/12/14 Valorisation of plastic waste: degradation based on enzymatic depolymerization
(Thesis) Main arguer
 Mariana Isabel dos Santos Aguiar (Master)
Universidade de Aveiro, Portugal
2022/07/29 Purification and stability of antibodies using alternative materials and solvents
(Thesis) Main arguer
 Ana Sofia Correia Marques (Master)
Universidade de Aveiro, Portugal
2022 Innovative and sustainable platforms for the downstream processing of antibody-based biopharmaceuticals
(Thesis) Arguer
 Emanuel Augusto Vieira Capela (PhD)
Universidade de Aveiro, Portugal
2021/07/28 Integrated recovery-purification strategies of protein-based biopharmaceuticals
(Thesis) Main arguer
 João Luís Pereira Fernandes (Other)
Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
2020/12/18 Optimization of L-asparaginase production by Bacillus Subtilis
Supervisor
 Daniel Figueiredo de Castro (Master)
Universidade de Aveiro, Portugal
2020/07/24 Carbon nanotubes as a novel platform for L-asparaginase immobilization
(Thesis) Main arguer
 João Gonçalves Pinho (Master)
Universidade do Porto Faculdade de Engenharia, Portugal

Journal scientific committee

Journal title (ISSN) Publisher
2022/10 - Current Pharmaceuticals MDPI
2022/09 - Current Scientific Reports Nature
2022/09 - Current Fermentation MDPI
2022/01 - Current Molecules MDPI
2021/10 - Current Foods (2304-8158) MDPI
2020/12 - Current Journal of Chemistry Hindawi
2020/05 - Current Separation and Purification Technology (1383-5866) Elsevier
2022 - 2022 BioTech-Guest Editor of the Special Issue: Progress on the Production, Purification and Applications of Microbial Enzymes MDPI

Mentoring / Tutoring

Topic Student name
2016/09 - 2017/10 MSc thesis Filipe Miguel Garcia Ferreira
2015/09 - 2016/07 MSc thesis Juliana Meixedo Calheiros
2014/09 - 2015/07 MSc thesis Joana Margarida Mota Gomes
2014/09 - 2015/05 MSc thesis Judite Sofia Santos Resende
2014/02 - 2014/07 BSc final project Emanuel Augusto Vieira Capela

Other jury / evaluation

Activity description Institution / Organization
2021/07/13 - Current Jury member in the evaluation of Thesis Proposal Preparation-Doctorate in Chemical Enginnering curricular plan from Flávia Carina Freitas Magalhães Universidade de Aveiro, Portugal
2021/02 - Current Jury member in the evaluation of Thesis Proposal Preparation-Doctorate in Biotecnhology curricular plan from Ana Catarina Almeida Santos Universidade de Aveiro, Portugal
2021/02 - Current Jury member in the evaluation of Thesis Proposal Preparation-Doctorate in Biotecnhology curricular plan from João Cláudio Fonseca Nunes Universidade de Aveiro, Portugal
2019/07 - Current Jury member in the evaluation of Thesis Proposal Preparation-Doctorate in Chemical Engineering curricular plan from Marguerita Evangelho da Rosa Universidade de Aveiro, Portugal
2016/04 - Current In the aim of the 8th Biochemistry Day at University of Aveiro, the BSc and MSc students in Biochemistry were invited to present their works in the form of a poster, based on the available bibliography, current knowledge or student’s experience on the subject. Me and my colleagues, PhD students in Biochemistry, evaluated the posters and decided the top three winners. Universidade de Aveiro Departamento de Química, Portugal
2017/04 - 2017/04 In the aim of the 9th Biochemistry Day at University of Aveiro, the BSc and MSc students in Biochemistry were invited to present their works in the form of a poster, based on the available bibliography, current knowledge or student’s experience on the subject. Me and my colleagues, PhD students in Biochemistry, evaluated the posters and decided the top three winners. Universidade de Aveiro Departamento de Química, Portugal
Distinctions

Award

2021 Best Poster Award
International Symposium on the Separation of Proteins, Peptides & Polynucleotides, Portugal
2017 Best Poster Award
Biopartitioning & Purification Conference, Brazil
2017 2nd Place at Conference Contest for Young Researchers
European Society of Biochemical Engineering Sciences, Germany
2016 Best Poster Award
Encontro Nacional de Estudantes de Química, Portugal

Other distinction

2022 Article highlighted on the Sustainable Chemistry homepage
MDPI AG, Switzerland
2019 Honorable Mention
Biopartitiong & Purification Conference 2019, Brazil