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I am a junior researcher at the Cancer Biology & Epigenetics Group (CBEG) in the Research Center of the Portuguese Oncology Institute of Porto (CI-IPOP). With a Scopus h-index of 25, I have published 56 papers in international peer-reviewed journals and 4 book chapters, accumulating 2014 citations and an impact factor of 330, indicating a significant impact in my field. I have been the first author on 12 papers and the senior author on 1. My scientific career began at the Centre for Neurosciences and Cell Biology - Vectors and Gene Therapy Lab, where I developed her BSc thesis on Liposomal vectors for cancer cell lines targeting. In 2008, I joined the Cancer Metabolism Group as a Fellowship Researcher at the Life and Health Sciences Research Institute (ICVS). In 2016, I obtained her PhD in Health Sciences from the School of Medicine, University of Minho, where I worked on Monocarboxylate Transporters (MCTs) in gliomas: Regulation and therapeutic implications, also at the Molecular Oncology Research Center, Barretos Cancer Hospital, São Paulo, Brazil. I moved to CI-IPOP in 2017 through a post-doctoral fellowship, and since January 2019, I have held a contract as a junior researcher (January 2019-June 2021 - FCT: POCI-01-0145-FEDER-29043; from July 2021 onwards - NORTE-01-0145-FEDER-072678). During my time at CI-IPOP, I have worked on several projects addressing the impact of epigenetics on tumour progression and therapy resistance, co-authoring 23 papers with an accumulated impact factor of 187. My research interests integrate Oncobiology (Urological Tumors), with a focus on the crossroads between tumour metabolism, cancer epigenetics and radiotherapy. I have consolidated a significant scientific output in the tumour metabolism and cancer epigenetic areas, allowing for the implementation of important skills for my research line implementation: Tumour Metabolism & Epigenetics crosstalk in cancer. So far, this has resulted in 3 review papers, 2 original papers (1 as the last author), and 1 book chapter within this research topic. In this research area, I have an accumulated impact factor of 27. Since 2017, I have participated in the supervision of 1 BSc student, 11 MSc students, and since 2020, I have been enrolled as supervisor of 2 PhD students. I am an active member of the scientific community, contributing to the lecturing of practical and theoretical classes from MSc/PhD programs in Medicine and Molecular Oncology at FMUP, and from the MSc program in Oncology at ICBAS-UP. Additionally, I was an invited assistant professor (30%) at the School of Health Sciences - Polytechnic of Porto (ESS-UP), where I teached the curricular unit Oncobiology. My work has been nationally and internationally recognized through 8 selected oral presentations in scientific meetings, invitations to review for Clinical Epigenetics, BMC Cancer, Cancers, among others, and participation in 9 scientific juries. I currently manage and supervise the MCTKidCan, EpiMetaboK, and EpiPaRty-funded projects and I am also a member of the H2020 Marie Sklodowska-Curie Action - PROSTAMET.
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Identification

Personal identification

Full name
Vera Mónica Miranda Gonçalves

Citation names

  • Vera Miranda-Gonçalves

Author identifiers

Ciência ID
8E1B-B722-284F
ORCID iD
0000-0002-4231-5532
Scopus Author Id
47361242700

Email addresses

  • vera.miranda.goncalves@ipoporto.min-saude.pt (Professional)

Telephones

Telephone
  • 225084000 Ext.: 1953 (Professional)

Addresses

  • Research Center of Portuguese Oncology Institute of Porto . Rua Dr. António Bernardino de Almeida , 4200-072, Porto, Porto, Portugal (Professional)

Websites

Knowledge fields

  • Medical and Health Sciences - Health Sciences
  • Natural sciences - Biological Sciences - Biochemistry
  • Natural sciences - Biological Sciences - Molecular Biology

Languages

Language Speaking Reading Writing Listening Peer-review
English Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2)
Portuguese (Mother tongue)
Education
Degree Classification
2024/11/05 - 2024/11/26
Concluded
 Advanced R programming for multi-omics data analysis (Outros)
Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal
2018
Concluded
 Advanced Training Course in Human Laboratory Genetics - Molecular Genetics (Outros)
Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal
 14
2018
Concluded
 Advanced Training Course in Human Laboratory Genetics - Biochemical Genetics (Outros)
Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal
 18
2018
Concluded
 Advanced Training Course in Human Laboratory Genetics - Clinical Laboratory Genetics (Outros)
Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal
 18
2012 - 2016
Concluded
 PhD in Health Scencies (Doutoramento)
Universidade do Minho Escola de Medicina, Portugal
"Monocarboxylate Transporters in gliomas: regulation and therapeutic implications" (THESIS/DISSERTATION)
 Muito Bom
2015
Concluded
 Controversies and Development in Gastric Cancer (Outros)
Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal
2014
Concluded
 Bioinformatics mini-course (Outros)
São Paulo School of Advanced Sciences, Brazil
2013
Concluded
 Laboratorial Rotation - Tumor metabolic plasticity: Gluconeogenesis pathway as an alternative source of glucose (Outros)
Instituto Português de Oncologia de Lisboa Francisco Gentil EPE Unidade de Investigação em Patobiologia Molecular, Portugal
 19
2013
Concluded
 Laboratorial Rotation - Oxidative stress: Cell death mechanism of Parthenolide in Diffuse Large B cell Lymphoma (Outros)
Universidade de Coimbra Faculdade de Medicina, Portugal
 19
2010 - 2012
Concluded
 MSc in Health Sciences (Mestrado)
Universidade do Minho Escola de Medicina, Portugal
"Role of monocarboxylate transporters in the metabolic remodelling of glioblastomas" (THESIS/DISSERTATION)
 17
2011
Concluded
 An Integrative Approach to Cell Analysis (Outros)
Universidade do Minho Escola de Medicina, Portugal
 16
2010
Concluded
 Radioactive Materials: How to deal with radioactive material (Outros)
Universidade do Minho Escola de Medicina, Portugal
2010
Concluded
 Biostatistics in Health Sciences (Outros)
Universidade do Minho Escola de Medicina, Portugal
 14
2010
Concluded
 Laboratory Animal Sciences (Outros)
Universidade do Minho Escola de Medicina, Portugal
 16
2010
Concluded
 Bioinformatics in Health Sciences (Outros)
Universidade do Minho Escola de Medicina, Portugal
 18
2009
Concluded
 Applications of flow cytometry in biomedical research (Outros)
Universidade do Minho Escola de Medicina, Portugal
2004 - 2008
Concluded
 BSc in Biochemistry (Licenciatura)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"Targeting of Lipossomal Vectors for cancer cell lines" (THESIS/DISSERTATION)
 16
2007
Concluded
 Voluntary Internship - Clinical Analysis (Outros)
Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal
Affiliation

Science

Category
Host institution 		Employer
2019/01/02 - Current Researcher (Research) Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
2017 - 2018 Postdoc (Research) Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
2008 - 2012 Research Assistant (Research) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal

Teaching in Higher Education

Category
Host institution 		Employer
2019 - Current Invited Assistant Professor (University Teacher) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2023/03/27 - 2023/07/28 Invited Assistant (Polytechnic Teacher) Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
Instituto Politécnico do Porto Escola Superior de Saúde, Portugal

Others

Category
Host institution 		Employer
2012 - 2016 PhD Fellowship Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2014/06 - 2014/10 PhD student Centro de Pesquisa em Oncologia Molecular, Hospital do Câncer de Barretos, Brazil
Centro de Pesquisa em Oncologia Molecular, Hospital do Câncer de Barretos, Brazil
Projects

Grant

Designation Funders
2024/01/01 - Current DNA methylation-based biomarkers as a novel minimal invasive technique for prostate cancer prognostication upon radiotherapeutic treatment (MethProstaR)
LPCC NRN 2024
Supervisor
Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
 Liga Portuguesa Contra o Cancro Núcleo Regional do Norte
Ongoing
2022/01 - 2022/12 The role of VHL/HIF axis- dependent metabolic profile in clear cell renal cell carcinoma aggressiveness
LPCC NRN 2022
Supervisor
Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
 Liga Portuguesa Contra o Cancro Núcleo Regional do Norte
Ongoing
2017 - 2018 ESTIMA: Early-stage cancer treatment, driven by context of molecular imaging
NORTE-01-0145-FEDER-000027
Post-doc Fellow
Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing

Contract

Designation Funders
2018/08/10 - 2021/12/31 ACCuseD renAl Cell Carcinoma Detection Renal Cancer detection: a translational metabolomics research based on Volatile Organic Compounds fingerprinting
PTDC/SAU-SER/30388/2017
Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal

Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal

Associação para a Inovação e Desenvolvimento da FCT, Portugal

Fundação Ensino e Cultura Fernando Pessoa, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2019 - 2021 Development of novel prognostic and predictive epigenetic biomarkers for malignant testicular germ cell tumors
POCI-01-0145-FEDER-29043
Researcher
Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2011 - 2014 Potential predictive biomarkers of anti-RTKs therapy response in gliomas: An “in vitro” and “in vivo” Study
info:eu-repo/grantAgreement/FCT/5876-PPCDTI/114549/PT
Other
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2010/04/01 - 2013/06/30 Transportadores de monocarboxilatos como potenciais alvos terapêuticos em cancro: estudos de inibição em modelos de tumores sólidos
PTDC/SAU-FCF/104347/2008
Universidade do Minho, Portugal

Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2011/04/01 - 2013 Role of monocarboxylate transporters (MCTs) in the metabolism of prostate cancer
info:eu-repo/grantAgreement/FCT/5876-PPCDTI/113415/PT
Other
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded

Other

Designation Funders
2023 - Current PROSTAMET - A comprehensive Translational Research and Training Pipeline Harnessing Lipid Metabolism to Improve PROSTate Cancer Management and Educate Young Researchers in Tackling Complex Disease
101120283
Researcher
Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal
 EU Framework Programme for Research and Innovation Marie Sklodowska-Curie Actions
Ongoing
2022 - Current EpiMetaboK: Epitrasnciptomic alterations within renal cancer metabolism reprogramming: uncovering new targets
CI-IPOP 08-2022
Researcher
Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal
 Instituto Português de Oncologia do Porto Francisco Gentil EPE
Ongoing
2020 - Current EpiPaRty: Dissecting the interplay between epigenetics and radiotherapy resistance in prostate cancer
CI-IPOP-152-2021
Researcher
Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal
 Instituto Português de Oncologia do Porto Francisco Gentil EPE
Ongoing
2017 - Current MCTKidCan: epigenetics and tumour metabolism crosstalk in kidney cancer
CI-IPOP-92-2018
Researcher
Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
 Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação
Ongoing
2013 - 2016 Estudo do efeito antineoplásico de extratos e derivados de Euphorbia tirucalli em tumores cerebrais e células tronco tumorais cerebrais
MCTI/CNPq Nº73/2013
Other
Hospital de Câncer de Barretos, Brazil
 Conselho Nacional de Desenvolvimento Científico e Tecnológico
Concluded
Outputs

Publications

Book chapter
  1. Vera Miranda-Gonçalves; Catarina Guimarães-Teixeira; Rui Henrique; Carmen Jerónimo. "Metabolic regulation in urological tumors: interplay with epigenetics and epitranscriptomics". In Epigenetics and Metabolomics. Elsevier, 2021.
    Published
  2. Ana C. Fernandes; Cláudia Caeiro; Vera Miranda-Gonçalves; Fernanda Cury; Margarida Damasceno; Rui M. Reis; Olga Martinho. "Bevacizumab for Glioblastoma Treatment: Reviewing Biological and Clinical Hypothesis for its Success and Failures". In Anti-Angiogenesis Drug Discovery and Development, 175-226. BENTHAM SCIENCE PUBLISHERS, 2016.
    Published • 10.2174/9781681081557116030007
  3. Céline Pinheiro; Filipa Morais-Santos; Sara Granja; Vera Miranda-Gonçalves; Julieta Afonso; Ricardo Amorim; Fátima Baltazar. "Targeting Metabolic Reprogramming as an Anti- Cancer Strategy: Aiming at Monocarboxylate Transporters". In Frontiers in Anti-Cancer Drug Discovery, 3-65. BENTHAM SCIENCE PUBLISHERS, 2015.
    Published • 10.2174/9781681081496115060003
  4. Gonçalves, Vera Miranda; Baltazar, Fátima; Reis, Rui Manuel. "Brain Tumor Metabolism — Unraveling Its Role in Finding New Therapeutic Targets". In Molecular Considerations and Evolving Surgical Management Issues in the Treatment of Patients with a Brain Tumor. InTech, 2015.
    Published • 10.5772/59606
Conference poster
  1. Carriço, Íris; Catarina Macedo-Silva; João A.M. Santos; Carmen Jerónimo; Vera Miranda-Gonçalves. "Epigenetic and Metabolic Insights in Prostate Cancer Radioresistance". Paper presented in 2nd Young Researchers Day, 2024.
  2. Fernandes-Pontes, Fernanda; Constâncio, Vera; Lobo, João; Henrique, Rui; Jerónimo, Carmen; Vera Miranda-Gonçalves. Corresponding author: Vera Miranda-Gonçalves. "Uncovering the interplay between epigenetics and metabolism in sarcomatoid Renal Cell Carcinoma: A novel era for biomarkers". Paper presented in 2nd Young Researchers Day, 2024.
  3. Vera Miranda-Gonçalves; Carriço, Íris; Macedo-Silva, Catarina; Lencart, Joana; Henrique, Rui; Carmen Jerónimo. "EPIGENETIC INSIGHTS INTO PROSTATE CANCER RADIOTHERAPY: THERAPEUTIC INNOVATIONS FOR RADIOSENSITIZATION". Paper presented in RISE Day 2024, 2024.
  4. Oliveira-Sousa, Rúben; Carla Castro; Carriço, Íris; João A.M. Santos; Carmen Jerónimo; Vera Miranda-Gonçalves. "Impacto do horário do tratamento de radioterapia nos resultados oncológicos em pacientes com adenocarcinoma da próstata localizado: um estudo clínico observacional retrospetivo português". Paper presented in 6º ENCONTRO NACIONAL JOVENS INVESTIGADORES EM ONCOLOGIA - LPCC Norte, 2024.
  5. Angela Albuquerque-Castro; Vera Miranda-Gonçalves; Catarina Macedo-Silva; Angel Diaz-Lagares; Carmen Jerónimo. "A reprogramação metabólica como mecanismo de resistência à radioterapia em cancro da próstata: uma perspetiva epigenética". Paper presented in 6º ENCONTRO NACIONAL JOVENS INVESTIGADORES EM ONCOLOGIA - LPCC Norte, 2024.
  6. Carriço, Íris; Macedo-Silva, Catarina; João A.M. Santos; Carmen Jerónimo; Vera Miranda-Gonçalves. "Unravelling the Intricate Interplay Between Epigenetics and Metabolism to Overcome Radioresistance in Prostate Cancer". Paper presented in 48th European Radiation Research Society Meeting, 2024.
  7. Fernandes-Pontes, Fernanda; Constâncio, Vera; Jerónimo, Carmen; Henrique, Rui; Vera Miranda-Gonçalves. Corresponding author: Vera Miranda-Gonçalves. "The interplay between epigenetics and metabolism in sarcomatoid Renal Cell Carcinoma: A novel era for biomarkers?". Paper presented in IPO Porto Summit, 2024.
  8. Macedo-Silva, Catarina; Angela Albuquerque-Castro; Lencart, Joana; Carneiro, Isa; Nuno Tiago Tavares; Barros-Silva, Daniela; João Lobo; et al. "Epigenetic reprogramming as Hallmark of prostate cancer radiobiology". Paper presented in Young Researchers Day IPO Porto, 2023.
  9. Vera Miranda-Gonçalves; Ana Lameirinhas; Beatriz Costa; Catarina Macedo-Silva; Paula C.Dias; Verónica Ferreira; Rui Silva-Santos; et al. "Metabolic-epigenetic landscape recoding in renal cell carcinoma: towards new therapeutic strategies". Paper presented in III ASPIC-ASEICA International Meeting: Cancer Immunology, Tumor Microenvironment & Metastasis, 2023.
  10. Macedo-Silva, Catarina; Vera Miranda-Gonçalves; Nuno Tiago Tavares; Barros-Silva, Daniela; Angela Albuquerque-Castro; Lencart, Joana; Carneiro, Isa; et al. "Epigenetic modulation of p53 by GSK-J4 attenuates prostate cancer radioresistance". Paper presented in ImmunoRad, 2023.
  11. Vera Miranda-Gonçalves; Catarina Guimarães-Teixeira; Ana Lameirinhas; João Lobo; Paula C.Dias; Verónica Ferreira; Henrique, Rui; Carmen Jeronimo. "Uncover a lactate - sirtuin 6 crosstalk in the metabolic reprogramming of renal cell carcinoma". Paper presented in Symposium on Cancer Genomics and Epitranscriptomics: from the bench to the clinic, 2022.
  12. Catarina Guimarães-Teixeira; Barros-Silva, Daniela; João Lobo; Silva-Santos, Rui; Henrique, Rui; Vera Miranda-Gonçalves; Carmen Jeronimo. Corresponding author: Vera Miranda-Gonçalves. "N6-Methyladenosine RNA Modification and ts regulatory proteins in Renal Cell Carcinoma". Paper presented in Symposium on Cancer Genomics and Epitranscriptomics: from the bench to the clinic, 2022.
  13. Costa, Beatriz; João Lobo; Henrique, Rui; Carmen Jerónimo; Vera Miranda-Gonçalves. Corresponding author: Vera Miranda-Gonçalves. "A inter-relação entre VHL e o perfil metabólico no carcinoma renal de células claras: MCTs e agressividade tumoral". Paper presented in 4º ENJIO edição, 2022.
  14. Vera Miranda-Gonçalves; Ana Lameirinhas; Catarina Macedo-Silva; João Lobo; Paula C.Dias; Verónica Ferreira; Henrique, Rui; Carmen Jeronimo. "Lactate – Sirtuin 6 axis mediating a metabolic reprogramming in renal cell carcinoma". Paper presented in 5th ASPIC International Congress, 2022.
  15. Catarina Macedo-Silva; Constâncio, Vera; Vera Miranda-Gonçalves; Leite-Silva, Pedro; Salta, Sofia; João Lobo; Rita Guimarães; et al. "DNA methylation biomarkers to residual disease detection in esophageal cancer upon neoadjuvant chemoradiation.". Paper presented in 5th ASPIC International congress, 2022.
  16. Catarina Macedo-Silva; Oriana Ribeiro; Nuno Tiago Tavares; Vera Miranda-Gonçalves; Lencart, Joana; Rosário Benedetti; Correia, Margareta P; Lucia Atucci; Carmen Jeronimo. "Epigenetically-induced TP53 in radioresistante prostate cancer model: a new radiosensitizing strategy". Paper presented in EACR Congress - Innovative Cancer Science: Translating Biology to Medicine, 2022.
  17. Macedo-Silva, Catarina; Oriana Ribeiro; Nuno Tiago Tavares; Vera Miranda-Gonçalves; Joana Lencart; Sofia Silva; Benedetti, Rosaria; et al. "Epigenetically-induced TP53 in radioresistant prostate cancer model: A new radiosensitizing strategy.". Paper presented in EACR 2022 Congress ¿ Innovative Cancer Science: Translating Biology to Medicine., 2022.
  18. Filipa Amaro.; Carolina Pisoeiro; Maria João Valente; Vera Miranda-Gonçalves; Carmen Jerónimo; Rui Henrique; Maria de Lourdes Bastos; et al. "In vitro metabolic response of renal cell carcinoma and non-tumorigenic cells to tyrosine kinase inhibitors". Paper presented in Metabolomics 2022: the 18th Annual Conference of Metabolomics Society, Valencia, 19 a 23 junho de 202, 2022.
  19. Filipa Amaro; Carolina Pisoeiro; Maria João Valente; Vera Miranda-Gonçalves; , Carmen Jerónimo, Rui Henrique, Maria de Lourdes Bastos, Paula Guedes de Pinho, Márcia Carvalho, Joana Pinto. "Differential cellular effects of sunitinib and pazopanib targeted drugs for metastatic renal cell carcinoma ¿ an in vitro approach". Paper presented in APCF-TOXRUN, 2022.
  20. Vera Miranda-Gonçalves; João Lobo; Catarina Guimarães-Teixeira; Daniela Barros-Silva; Rita Guimarães; Mariana Cantante; Isaac Braga; et al. "The role of m6A methyltransferase VIRMA in testicular germ cell tumors aggressivness and cisplatin response". Paper presented in II ASPIC-ASEICA International Meeting: Current trends of precision medicine in cancer, 2021.
  21. Cláudia Martins-Lima; Lobo, João; Constâncio, Vera; Catarina Guimarães-Teixeira; Vera Miranda-Gonçalves; Monteiro-Reis, Sara; Ana Lameirinhas; et al. "EMT impact in bladder cancer progression: understanding the cadherins´ role and their regulatory mechanisms". Paper presented in Porto Cancer Meeting, 2021.
  22. Vera Miranda-Gonçalves; Ana Lameirinhas; João Lobo; Paula C. Dias; Verónica Ferreira; Rui Henrique; Carmen Jerónimo. "Role of lactate on sirtuin 1 modulation: an interplay in renal cell carcinoma aggressiveness". Paper presented in EACR-AACR-ASPIC Conference: Tumor Microenvironment, 2020.
  23. Filipa Quintela Vieira; Ângela Marques-Magalhães; Vera Miranda-Gonçalves; Ricardo Ferraz; Cristina Prudêncio; Carmen Jerónimo; Regina Augusta Silva. "Molecular impact of [C16Pyr][Amp] treatment on breast and prostate cancer cell lines". Paper presented in P.PORTO Research Workshops, 2019.
  24. Vera Miranda-Gonçalves; Ana Lameirinhas; Catarina Macedo-Silva; Rui Henrique; Carmen Jerónimo. "Lactate in renal cell carcinoma progression: modulation of epigenetic landscape". Paper presented in Epigenetics & Chromatin - Cold Spring Harbor Laboratory, 2018.
  25. Catarina Macedo-Silva; Vera Miranda-Gonçalves; Joana Lencart; Sofia Silva; Ana Lameirinhas; Rui Henrique; Isabel Bravo; Carmen Jerónimo. "Esophageal cancer therapy response: role of hypoxia in epigenetic mechanism regulation". Paper presented in ASPIC International Congress, 2018.
  26. Vera Miranda-Gonçalves; Ana lameirinhas; Catarina Macedo-Silva; Rui Henrique; Carmen Jerónimo. "Lactate modulates epigenetic mechanisms contributing to kidney cancer progression". Paper presented in ASPIC International Congress, 2018.
  27. Sara Monteiro-Reis; Ana Lameirinhas; Vera Miranda-Gonçalves; Diana Montezuma-Felizardo; Paula C. Dias; Jorge Oliveira; Inês Graça; Rui Henrique; Carmen Jerónimo. "Role of SIRT7 in invasive high grade bladder cancer". Paper presented in Epigenetics & Chromatin Cold Spring Harbor Laboratory, 2018.
  28. Vera Miranda-Gonçalves; Diana Cardoso-Carneiro; Inês Valbom; Fernanda Cury; Viviane Aline; Sara Granja; Fátima Baltazar; Rui Manuel Vieira Reis; Olga Catarina Lopes Martinho. "Understanding the cellular metabolic reprogramming associated with bevacizumab therapy in glioblastoma". Paper presented in ICVS Open day, 2017.
  29. Olga Martinho; Renato Silva-Oliveira; Fernanda Cury; Ana Martins Barbosa; Sara Granja; Adriane Feijó Evangelista; Fábio Marques; et al. "Blocking glucose metabolism enhances the effect of HER inhibitors in cervical cancer therapy". Paper presented in XIX Congresso Nacional da Sociedade Portuguesa de Bioquímica, Guimarãres (Portugal), 2016.
  30. Olga Martinho; Renato Silva-Oliveira; Fernanda Cury; Ana Martins Barbosa; Sara Granja; Fábio Marques; Vera Miranda-Gonçalves; et al. "HER receptors are important theranostic biomarkers on cervical cancer: blocking glucose metabolism enhances the therapeutic effect of HER inhibitors.". Paper presented in 16th Biennial Meeting of the International Gynecologic Cancer Society (IGCS 2016), 2016.
  31. Vera Miranda-Gonçalves; Filipa Berreza; Raquel Costa-Almeida; Marta Freitas-Cunha; Raquel Soares; Olga Martinho; Rui M. Reis; Céline Pinheiro; Fátima Baltazar. "Monocarboxylate Transporter 1 is an important player in tumor endothelial cell crosstalk in glioblastomas". Paper presented in ISCaM: Metabolic Network in Cancer, 2016.
  32. Vera Miranda-Gonçalves; Mrinalini Honavar; Manuel M. Pires; Célia Pinheiro; Michelle Cordeiro; Gil Bebiano; Paulo Costa; Rui M. Reis; Baltazar, F. "Monocarboxylate Transporter 1 (MCT1) expression at hypoxic conditions in glioblastomas: functional role and regulation". Paper presented in XXIII Porto Cancer Meeting - Stem Cells and Cancer, 2015.
  33. Filipa Morais-Santos; Sara Granja; Vera Miranda-Gonçalves; António H.J. Moreira; João L. Vilaça; Joana Paredes; Fernando C. Schmitt; Baltazar, F; Céline Pinheiro. "Targeting lactate transport suppresses in vivo breast tumor growth". Paper presented in XXIII Porto Cancer Meeting - Stem Cells and Cancer, 2015.
  34. Vera Miranda-Gonçalves; Ribeiro V. P.; Silva-Correia J.; Yan L. P.; Oliveira A.L.; Reis R.M.; Reis R.L.; Oliveira J.M.. "Novel Enzymatically Cross-linked Silk Fibroin Hydrogel with potential applications as supressor of angiogenesis and tumor progression". Paper presented in ESB - 27th European Conferenceon Biomaterials, 2015.
  35. Vera Miranda-Gonçalves; Mrinalini Honavar; Manuel M. Pires; Célia Pinheiro; Michelle Cordeiro; Gil Bebiano; Paulo Costa; Rui M. Reis; Fátima Baltazar. "MCT1 plasma membrae expression at hypoxic regions could be a mediator of cellular aggressiveness in glioblastomas". Paper presented in Stem cell and Cancer - XXIII Porto Cancer Meeting, 2015.
  36. Silva-Carvalho, Ricardo; Vera Miranda-Gonçalves; Ferreira, AM; Cardoso, Susana M.; Abilio J. F. N. Sobral; Almeida-Aguiar, Cristina. "Characterization of antitumor and antiangiogenic properties of Pereiro Propolis". Paper presented in 62nd International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research, 2014.
  37. Silva-Carvalho, Ricardo; Vera Miranda-Gonçalves; Ferreira, AM; Cardoso, Susana M.; Sobral, Abílio JFN; Almeida-Aguiar, Cristina; Baltazar, Fatima. "Characterization of the antitumoral and antiangiogenic activity of Portuguese propolis in in vitro and in vivo models". Paper presented in 3rd Iberian conference of Apiculture, Mirandela, Portugal, 2014.
  38. Vera Miranda-Gonçalves; Mrinalini Honavar; Rui M. Reis; Fátima Baltazar. "Involvemetn of Monocarboxylate Transporter 1 (MCT1) in glioblastoma aggressiveness". Paper presented in 1st ASPIC International Congress, 2014.
  39. Vera Miranda-Gonçalves; Mrinalini Honavar; Rui M. Reis; Fátima Baltazar. "Involvement of MCT1 at hypoxic regions in aggressiveness of glioblastomas". Paper presented in IV Simpósio Internacional de Oncologia Translational do Hospital de Câncer de Barretos, 2014.
  40. Vera Miranda-Gonçalves; Mrinalini Honavar; Rui M. Reis; Fátima Baltazar. "Involvement of Monocarboxylate Transporter 1 (MCT1) in glioblastoma aggressiveness". Paper presented in ESPCA: Oncogenesis and Translational Medicine for Cancer Therapy, 2014.
  41. Vera Miranda-Gonçalves; Mrinalini Honavar; Manuel M. Pires; Célia Pinheiro; Michelle Cordeiro; Gil Bebiano; Paulo Costa; Rui M. Reis; Fátima Baltazar. "MCT1 plasma membrane expression at hypoxic regions could be a mediator of celullar aggressiveness in glioblastomas". Paper presented in Congresso Nacional da Associação Portuguesa de Neuro-Oncologia (APNO), 2013.
  42. Filipa Bezerra; Marta Freitas-Cunha; Vera Miranda-Gonçalves; Céline Pinheiro; Fátima Baltazar. "Monocarboxylate transporters as a mediator in tumor-endothelial crosstalk". Paper presented in XXII Porto Cancer Meeting, 2013.
  43. Susana Sousa; Vera Miranda-Gonçalves; Nelma Pétrega-Gomes; José Ramón Vizcaíno; Carmen Jerónimo; Carlos Lopes; Fátima Baltazar; Rui Henrique. "The effect of MCT1 and MCT4 downregulation on prostate cancer survival and aggressiveness". Paper presented in XXII Porto Cancer Meeting, 2013.
  44. Julieta Afonso; Adhemar Longatto-Filho; Vera Miranda-Gonçalves; Nuno Sousa; António Morais; Teresina Amaro; Lúcio L. Santos; Fátima Baltazar. "CD147 and MCT1-Potential partners in bladder cancer aggressiveness and chemoressitance". Paper presented in XXII Porto Cancer Meeting, 2013.
  45. Vera Miranda-Gonçalves; Mrinalini Honavar; Céline Pinheiro; Olga Martinho; Rui M. Reis; Fátima Baltazar. "MCT1 plasma membrane expression is associated to hypoxic regions in glioblastomas". Paper presented in EACR22 - from Basic Research to Personalized Cancer Treatment, 2012.
  46. Vera Miranda-Gonçalves; Mrinalini Honavar; Céline Pinheiro; Olga Martinho; Michelle Cordeiro; Gil Bebiano; Paulo Costa; Rui M. Reis; Fátima Baltazar. "Hypoxia induce MCT1 plasma membrane expression in glioblastomas". Paper presented in XXI Porto Cancer Meeting: Metabolism and Cancer from Etiophatogenesis to Therapy, 2012.
  47. Vera Miranda-Gonçalves; Mrinalini Honavar; Céline Pinheiro; Olga Martinho; Paulo Costa; Rui M. Reis; Fátima Baltazar. "Targeting lactate transport in glioblastomas". Paper presented in 2nd Symposium of the International Society of Proton and Dynamics in Cancer (ISPDC), 2011.
  48. Vera Miranda-Gonçalves; Nelma Pétrega-Gomes; Tatiana Lourenço; Céline Pinheiro; Carmen Jerónimo; José Ramón Vizcaíno; Carlos Lopes; Fátima Baltazar. "Prostate Cancer: exploitation of monocarboxylate transporters as potential therapeutic targets". Paper presented in 39th Meeting of International Society of Oncology and Biomarkers (ISOBM), 2011.
  49. Vera Miranda-Gonçalves; Mrinalini Honavar; Céline Pinheiro; Olga Martinho; Paulo Costa; Rui M. Reis; Fátima Baltazar. "Monocarboxylate transporters as potential therapeutic target in glioblastomas". Paper presented in XX Porto Cancer Meeting - Drug Resistance in cancer: From biology to molecular targets and drugs, 2011.
  50. Marta Pojo; Tiago Gonçalves; Joana Cunha; Bernardo Gama; Vera Miranda-Gonçalves; Rui M. Reis; Bruno M Costa. "Influence of HOXA9 expression in the response of glioblastomas cell to Temozolomide". Paper presented in XX Porto Cancer Meeting - Drug Resistance: from biology to molecular targets and drugs, 2011.
  51. Vera Miranda-Gonçalves; Silva- Correia J.; Oliveira J.M.; Rui M. Reis; Rui L. Reis. "Methacrylated gellan gum hydrogels for application in nucleus pulposus regeneration: in vitro and in vivo studies". Paper presented in 24th European Conference on Biomaterials, 2011.
  52. Vera Miranda-Gonçalves; Céline Pinheiro; Mrinalini Honavar; Paulo Costa; Fátima Baltazar; Rui M. Reis. "Upregulation of MCT1 and its chaperone CD147 in glioblastomas". Paper presented in XIX Porto Cancer Meeting - Differentiation, Regeneration and Cancer, 2010.
  53. Céline Pinheiro; Silvia Pinheiro; Vera Miranda-Gonçalves; André Vieira; Joana Paredes; Fernando Schmitt; Fátima Baltazar. "Sensitivity of breast cancer cells to CHC, an inhibitor of monocarboxylate transporter 1". Paper presented in XIX Porto Cancer Meeting - Differentiation, Regeneration and Cancer, 2010.
  54. Vera Miranda-Gonçalves; Nelma Pétrega-Gomes; Céline Pinheiro; José Ramón Vizcaíno; Carlos Lopes; Fátima Baltazar. "Monocarboxylate Transporter 2 as a putative prostate cancer marker". Paper presented in XIX Porto Cancer Meeting - Differentiation, Regeneration and Cancer, 2010.
  55. Vera Miranda-Gonçalves; Céline Pinheiro; Honavar, Mrinalini; Paulo Costa; Fátima Baltazar; Rui M. Reis. "Therapeutic potential of MCT inhibitors in glioblastoma". Paper presented in 2º National Congress of Neuro-Oncology Portuguese Association, 2009.
Journal article
  1. Mariana Cantante; Vera Miranda-Gonçalves; Nuno Tiago Tavares; Rita Guimarães; Isaac Braga; Joaquina Maurício; Andres M. Acosta; et al. "Differential expression of metabolic enzymes in testicular germ cell tumors: The impact of glycolytic metabolism in embryonal carcinoma histotype". Andrology (2024): https://doi.org/10.1111/andr.13824.
    10.1111/andr.13824
  2. Nair Lopes; Sofia Salta; Bianca Troncarelli Flores; Vera Miranda-Gonçalves; Margareta P. Correia; Davide Gigliano; Rita Guimarães; Rui Henrique; Carmen Jerónimo. "Anti-tumour activity of Panobinostat in oesophageal adenocarcinoma and squamous cell carcinoma cell lines". Clinical Epigenetics (2024): http://dx.doi.org/10.1186/s13148-024-01700-3.
    10.1186/s13148-024-01700-3
  3. Catarina Macedo-Silva; Vera Miranda-Gonçalves; Nuno Tiago Tavares; Daniela Barros-Silva; Joana Lencart; João Lobo; Ângelo Oliveira; et al. "Epigenetic regulation of TP53 is involved in prostate cancer radioresistance and DNA damage response signaling". Signal Transduction and Targeted Therapy (2023): http://dx.doi.org/10.1038/s41392-023-01639-6.
    10.1038/s41392-023-01639-6
  4. Catarina Macedo-Silva; Vera Constâncio; Vera Miranda-Gonçalves; Pedro Leite-Silva; Sofia Salta; João Lobo; Rita Guimarães; et al. "DNA methylation biomarkers accurately detect esophageal cancer prior and post neoadjuvant chemoradiation". Cancer Medicine 12 7 (2023): 8777-8788. http://dx.doi.org/10.1002/cam4.5623.
    Published • 10.1002/cam4.5623
  5. Sara Monteiro-Reis; Vera Miranda-Gonçalves; Catarina Guimarães-Teixeira; Cláudia Martins-Lima; João Lobo; Diana Montezuma; Paula C. Dias; et al. "Vimentin epigenetic deregulation in Bladder Cancer associates with acquisition of invasive and metastatic phenotype through epithelial-to-mesenchymal transition". International Journal of Biological Sciences 19 1 (2023): 1-12. http://dx.doi.org/10.7150/ijbs.77181.
    Published • 10.7150/ijbs.77181
  6. Martins, Eduarda P.; Gonçalves, Céline S.; Pojo, Marta; Carvalho, Rita; Ribeiro, Ana S.; Miranda-Gonçalves, Vera; Taipa, Ricardo; et al. "Cadherin-3 is a novel oncogenic biomarker with prognostic value in glioblastoma". Molecular Oncology (2022): http://dx.doi.org/10.1002/1878-0261.13162.
    Published • 10.1002/1878-0261.13162
  7. Florian A. Büttner; Stefan Winter; Viktoria Stühler; Steffen Rausch; Jörg Hennenlotter; Susanne Füssel; Stefan Zastrow; et al. "A novel molecular signature identifies mixed subtypes in renal cell carcinoma with poor prognosis and independent response to immunotherapy". Genome Medicine 14 1 (2022): http://dx.doi.org/10.1186/s13073-022-01105-y.
    Published • 10.1186/s13073-022-01105-y
  8. Ana Salomé Correia; D. Duarte; Vera Miranda-Gonçalves; Nuno Vale. "Potential Translational Thioflavin T Methodology as a Complement of Cell-Based Assays and after Drug Exposition". International Journal of Translational Medicine (2022): https://www.mdpi.com/2673-8937/2/2/11.
    10.3390/ijtm2020011
  9. Beatriz Chaves Lourenço; Catarina Guimarães-Teixeira; Bianca C. T. Flores; Vera Miranda-Gonçalves; Rita Guimarães; Mariana Cantante; Paula Lopes; et al. "Ki67 and LSD1 Expression in Testicular Germ Cell Tumors Is Not Associated with Patient Outcome: Investigation Using a Digital Pathology Algorithm". Life 12 2 (2022): 264-264. https://doi.org/10.3390/life12020264.
    Published • 10.3390/life12020264
  10. Cláudia Martins-Lima; Vera Miranda-Gonçalves; João Lobo; Vera Constâncio; Pedro Leite-Silva; Catarina Guimarães-Teixeira; Sara Monteiro-Reis; et al. "Cadherin switches during epithelial-mesenchymal transition: CDH4/RCAD downregulation reduces bladder cancer progression". Cellular Oncology (2022): https://doi.org/10.1007/s13402-021-00657-2.
    Published • 10.1007/s13402-021-00657-2
  11. Guimarães-Teixeira, Catarina; Lobo, João; Miranda-Gonçalves, Vera; Barros-Silva, Daniela; Martins-Lima, Cláudia; Monteiro-Reis, Sara; Sequeira, José Pedro; et al. "Downregulation of m6A writer complex member METTL14 in bladder urothelial carcinoma suppresses tumor aggressiveness". Molecular Oncology (2022): http://dx.doi.org/10.1002/1878-0261.13181.
    Published • 10.1002/1878-0261.13181
  12. Catarina Guimarães-Teixeira; Daniela Barros-Silva; João Lobo; Diana Soares-Fernandes; Vera Constâncio; Pedro Leite-Silva; Rui Silva-Santos; et al. Corresponding author: Vera Miranda-Gonçalves. "Deregulation of N6-Methyladenosine RNA Modification and Its Erasers FTO/ALKBH5 among the Main Renal Cell Tumor Subtypes". Journal of Personalized Medicine 11 10 (2021): https://doi.org/10.3390/jpm11100996.
    Published • 10.3390/jpm11100996
  13. Marques-Magalhães, Ângela; Graça, Inês; Miranda-Gonçalves, Vera; Henrique, Rui; Lopez, Marie; Arimondo, Paola B.; Jerónimo, Carmen. "Anti-neoplastic and demethylating activity of a newly synthetized flavanone-derived compound in Renal Cell Carcinoma cell lines". Biomedicine & Pharmacotherapy 141 (2021): 111681. http://dx.doi.org/10.1016/j.biopha.2021.111681.
    Published • 10.1016/j.biopha.2021.111681
  14. Vera Miranda-Gonçalves; João Lobo; Catarina Guimarães-Teixeira; Daniela Barros-Silva; Rita Guimarães; Mariana Cantante; Isaac Braga; et al. "The component of the m6A writer complex VIRMA is implicated in aggressive tumor phenotype, DNA damage response and cisplatin resistance in germ cell tumors". Journal of Experimental & Clinical Cancer Research (2021): https://doi.org/10.1186/s13046-021-02072-9.
    Published • 10.1186/s13046-021-02072-9
  15. Vera Miranda-Gonçalves; Céline S. Gonçalves; Sara Granja; Joana Vieira de Castro; Rui M. Reis; Bruno M. Costa; Fátima Baltazar. "MCT1 Is a New Prognostic Biomarker and Its Therapeutic Inhibition Boosts Response to Temozolomide in Human Glioblastoma". Cancers 13 14 (2021): 3468-3468. https://doi.org/10.3390/cancers13143468.
    Published • 10.3390/cancers13143468
  16. Talukdar, Fazlur Rahman; Soares Lima, Sheila C.; Khoueiry, Rita; Laskar, Ruhina Shirin; Cuenin, Cyrille; Sorroche, Bruna Pereira; Boisson, Anne-Claire; et al. "Genome-Wide DNA Methylation Profiling of Esophageal Squamous Cell Carcinoma from Global High-Incidence Regions Identifies Crucial Genes and Potential Cancer Markers". Cancer Research 81 10 (2021): 2612-2624. http://dx.doi.org/10.1158/0008-5472.can-20-3445.
    Published • 10.1158/0008-5472.can-20-3445
  17. João Lobo; Vera Constâncio; Catarina Guimarães-Teixeira; Pedro Leite-Silva; Vera Miranda-Gonçalves; José Pedro Sequeira; Laura Pistoni; et al. "Promoter methylation of DNA homologous recombination genes is predictive of the responsiveness to PARP inhibitor treatment in testicular germ cell tumors.". Molecular oncology (2021): https://doi.org/10.1002/1878-0261.12909.
    Published • 10.1002/1878-0261.12909
  18. João Lobo; Ana Rita Cardoso; Vera Miranda-Gonçalves; Leendert H. J. Looijenga; Marie Lopez; Paola B. Arimondo; Rui Henrique; Carmen Jerónimo. "Targeting Germ Cell Tumors with the Newly Synthesized Flavanone-Derived Compound MLo1302 Efficiently Reduces Tumor Cell Viability and Induces Apoptosis and Cell Cycle Arrest". Pharmaceutics 13 1 (2021): 73-73. https://doi.org/10.3390/pharmaceutics13010073.
    Published • 10.3390/pharmaceutics13010073
  19. Filipa Quintela Vieira; Ângela Marques-Magalhães; Vera Miranda-Gonçalves; Ricardo Ferraz; Mónica Vieira; Cristina Prudêncio; Carmen Jerónimo; Regina Augusta Silva. "The Impact of [C16Pyr][Amp] on the Aggressiveness in Breast and Prostate Cancer Cell Lines". International Journal of Molecular Sciences 21 24 (2020): 9584-9584. https://doi.org/10.3390/ijms21249584.
    Published • 10.3390/ijms21249584
  20. Catarina Macedo-Silva; Vera Miranda-Gonçalves; Ana Lameirinhas; Joana Lencart; Alexandre Pereira; João Lobo; Rita Guimarães; et al. "JmjC-KDMs KDM3A and KDM6B modulate radioresistance under hypoxic conditions in esophageal squamous cell carcinoma.". Cell death & disease (2020): https://doi.org/10.1038/s41419-020-03279-y.
    Published • 10.1038/s41419-020-03279-y
  21. Sofia Salta; Catarina Macedo-Silva; Vera Miranda-Gonçalves; Nair Lopes; David Gigliano; Rita Guimarães; Mónica Farinha; et al. "A DNA methylation-based test for esophageal cancer detection.". Biomarker research (2020): https://europepmc.org/articles/PMC7691099.
    Published • 10.1186/s40364-020-00248-7
  22. Andreia Pereira-Nunes; Susana Simões-Sousa; Céline Pinheiro; Vera Miranda-Gonçalves; Sara Granja; Fátima Baltazar, PhD. "Targeting lactate production and efflux in prostate cancer". Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1866 11 (2020): 165894-165894. http://dx.doi.org/10.1016/j.bbadis.2020.165894.
    10.1016/j.bbadis.2020.165894
  23. João Lobo; Catarina Guimarães-Teixeira; Daniela Barros-Silva; Vera Miranda-Gonçalves; Vânia Camilo; Rita Guimarães; Mariana Cantante; et al. "Efficacy of HDAC Inhibitors Belinostat and Panobinostat against Cisplatin-Sensitive and Cisplatin-Resistant Testicular Germ Cell Tumors". Cancers (2020): https://doi.org/10.3390/cancers12102903.
    10.3390/cancers12102903
  24. João Lobo; Rita Guimarães; Vera Miranda-Gonçalves; Sara Monteiro-Reis; Mariana Cantante; Luís Antunes; Isaac Braga; et al. "Differential expression of DNA methyltransferases and demethylases among the various testicular germ cell tumor subtypes". Epigenomics 12 18 (2020): 1579-1592. http://dx.doi.org/10.2217/epi-2020-0066.
    10.2217/epi-2020-0066
  25. Ana Rita Cardoso; João Lobo; Vera Miranda-Gonçalves; Rui Henrique; Carmen Jerónimo. "Epigenetic alterations as therapeutic targets in Testicular Germ Cell Tumours : current and future application of ‘epidrugs’". Epigenetics (2020): https://doi.org/10.1080/15592294.2020.1805682.
    10.1080/15592294.2020.1805682
  26. Vera Miranda-Gonçalves; Ana Lameirinhas; Rui Henrique; Fátima Baltazar; Carmen Jerónimo. "The metabolic landscape of urological cancers: New therapeutic perspectives". Cancer Letters 477 (2020): 76-87. https://doi.org/10.1016/j.canlet.2020.02.034.
    10.1016/j.canlet.2020.02.034
  27. Filipa Amaro; Joana Pinto; Sílvia Rocha; Ana Margarida Araújo; Vera Miranda-Gonçalves; Carmen Jerónimo; Rui Henrique; et al. "Volatilomics Reveals Potential Biomarkers for Identification of Renal Cell Carcinoma: An In Vitro Approach". Metabolites 10 5 (2020): 174-174. https://doi.org/10.3390/metabo10050174.
    10.3390/metabo10050174
  28. Sara Monteiro-Reis; Ana Lameirinhas; Vera Miranda-Gonçalves; Diana Felizardo; Paula C. Dias; Jorge Oliveira; Inês Graça; et al. "Sirtuins’ Deregulation in Bladder Cancer: SIRT7 Is Implicated in Tumor Progression through Epithelial to Mesenchymal Transition Promotion". Cancers 12 5 (2020): 1066-1066. http://dx.doi.org/10.3390/cancers12051066.
    10.3390/cancers12051066
  29. Vera Miranda-Gonçalves; Ana Lameirinhas; Catarina Macedo-Silva; João Lobo; Paula C. Dias; Verónica Ferreira; Rui Henrique; Carmen Jerónimo. "Lactate Increases Renal Cell Carcinoma Aggressiveness through Sirtuin 1-Dependent Epithelial Mesenchymal Transition Axis Regulation". Cells (2020):
    Published
  30. Vera Miranda-Gonçalves. "The T-box transcription factor brachyury behaves as a tumor suppressor in gliomas.". The Journal of pathology (2020): https://doi.org/10.1002/path.5419.
    10.1002/path.5419
  31. Catarina Macedo-Silva; Vera Miranda-Gonçalves; Rui Henrique; Carmen Jerónimo; Isabel Bravo. "The Critical Role of Hypoxic Microenvironment and Epigenetic Deregulation in Esophageal Cancer Radioresistance". Genes (2019): http://dx.doi.org/10.3390/genes10110927.
    Published • 10.3390/genes10110927
  32. Lobo; Nunes; Gillis; Barros-Silva; Miranda-Gonçalves; Berg; Cantante; et al. "XIST-Promoter Demethylation as Tissue Biomarker for Testicular Germ Cell Tumors and Spermatogenesis Quality". Cancers 11 9 (2019): 1385. http://dx.doi.org/10.3390/cancers11091385.
    Published • 10.3390/cancers11091385
  33. Ana Lameirinhas; Vera Miranda-Gonçalves; Rui Henrique; Carmen Jeronimo. "The Complex Interplay between Metabolic Reprogramming and Epigenetic Alterations in Renal Cell Carcinoma". Genes (2019): https://www.mdpi.com/2073-4425/10/4/264.
    Published • 10.3390/genes10040264
  34. Miranda-Gonçalves, V.; Lameirinhas, A.; Henrique, R.; Jerónimo, C.. "Metabolism and epigenetic interplay in cancer: Regulation and putative therapeutic targets". Frontiers in Genetics 9 OCT (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85055323422&partnerID=MN8TOARS.
    10.3389/fgene.2018.00427
  35. Silva, V.A.O.; Rosa, M.N.; Miranda-Gonçalves, V.; Costa, A.M.; Tansini, A.; Evangelista, A.F.; Martinho, O.; et al. "Euphol, a tetracyclic triterpene, from Euphorbia tirucalli induces autophagy and sensitizes temozolomide cytotoxicity on glioblastoma cells". Investigational New Drugs (2018): 1-15. http://www.scopus.com/inward/record.url?eid=2-s2.0-85048839289&partnerID=MN8TOARS.
    10.1007/s10637-018-0620-y
  36. Vilaça, N.; Totovao, R.; Prasetyanto, E.A.; Miranda-Gonçalves, V.; Morais-Santos, F.; Fernandes, R.; Figueiredo, F.; et al. "Internalization studies on zeolite nanoparticles using human cells". Journal of Materials Chemistry B 6 3 (2018): 469-476. http://www.scopus.com/inward/record.url?eid=2-s2.0-85040868389&partnerID=MN8TOARS.
    10.1039/c7tb02534c
  37. Ferreira, N.N.; M.B. Ferreira, L.; Miranda-Gonçalves, V.; Reis, R.M.; Seraphim, T.V.; Borges, J.C.; Baltazar, F.; Gremião, M.P.D.. "Alginate hydrogel improves anti-angiogenic bevacizumab activity in cancer therapy". European Journal of Pharmaceutics and Biopharmaceutics 119 (2017): 271-282. http://www.scopus.com/inward/record.url?eid=2-s2.0-85021992926&partnerID=MN8TOARS.
    10.1016/j.ejpb.2017.06.028
  38. Miranda-Gonçalves, V.; Bezerra, F.; Costa-Almeida, R.; Freitas-Cunha, M.; Soares, R.; Martinho, O.; Reis, R.M.; Pinheiro, C.; Baltazar, F.. "Monocarboxylate transporter 1 is a key player in glioma-endothelial cell crosstalk". Molecular Carcinogenesis 56 12 (2017): 2630-2642. http://www.scopus.com/inward/record.url?eid=2-s2.0-85028302772&partnerID=MN8TOARS.
    10.1002/mc.22707
  39. Miranda-Gonçalves, V.; Cardoso-Carneiro, D.; Valbom, I.; Cury, F.P.; Silva, V.A.; Granja, S.; Reis, R.M.; Baltazar, F.; Martinho, O.. "Metabolic alterations underlying Bevacizumab therapy in glioblastoma cells". Oncotarget 8 61 (2017): 103657-103670. http://www.scopus.com/inward/record.url?eid=2-s2.0-85035349210&partnerID=MN8TOARS.
    10.18632/oncotarget.21761
  40. Martinho, Olga; Silva-Oliveira, Renato; Cury, Fernanda P.; Barbosa, Ana Martins; Granja, Sara; Evangelista, Adriane Feijó; Marques, Fábio; et al. "HER Family Receptors are Important Theranostic Biomarkers for Cervical Cancer: Blocking Glucose Metabolism Enhances the Therapeutic Effect of HER Inhibitors". Theranostics 7 3 (2017): 717-732. http://dx.doi.org/10.7150/thno.17154.
    Published • 10.7150/thno.17154
  41. Pinheiro, C.; Miranda-Gonçalves, V.; Longatto-Filho, A.; Vicente, A.L.S.A.; Berardinelli, G.N.; Scapulatempo-Neto, C.; Costa, R.F.A.; et al. "The metabolic microenvironment of melanomas: Prognostic value of MCT1 and MCT4". Cell Cycle 15 11 (2016): 1462-1470. http://www.scopus.com/inward/record.url?eid=2-s2.0-84969138646&partnerID=MN8TOARS.
    10.1080/15384101.2016.1175258
  42. Yan, L.-P.; Silva-Correia, J.; Ribeiro, V.P.; Miranda-Goncalves, V.; Correia, C.; Da Silva Morais, A.; Sousa, R.A.; et al. "Tumor Growth Suppression Induced by Biomimetic Silk Fibroin Hydrogels". Scientific Reports 6 (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-84982730530&partnerID=MN8TOARS.
    10.1038/srep31037
  43. Miranda-Gonçalves, V.; Granja, S.; Martinho, O.; Honavar, M.; Pojo, M.; Costa, B.M.; Pires, M.M.; et al. "Hypoxia-mediated upregulation of MCT1 expression supports the glycolytic phenotype of glioblastomas". Oncotarget 7 29 (2016): 46335-46353. http://www.scopus.com/inward/record.url?eid=2-s2.0-84979950555&partnerID=MN8TOARS.
    10.18632/oncotarget.10114
  44. Miranda-Gonçalves, V.; Reis, R.M.; Baltazar, F.. "Lactate transporters and pH regulation: Potential therapeutic targets in glioblastomas". Current Cancer Drug Targets 16 5 (2016): 388-399. http://www.scopus.com/inward/record.url?eid=2-s2.0-84973664272&partnerID=MN8TOARS.
    10.2174/1568009616666151222150543
  45. Amorim, R.; Pinheiro, C.; Miranda-Gonçalves, V.; Pereira, H.; Moyer, M.P.; Preto, A.; Baltazar, F.. "Monocarboxylate transport inhibition potentiates the cytotoxic effect of 5-fluorouracil in colorectal cancer cells". Cancer Letters 365 1 (2015): 68-78. http://www.scopus.com/inward/record.url?eid=2-s2.0-84930823940&partnerID=MN8TOARS.
    10.1016/j.canlet.2015.05.015
  46. Afonso, J.; Santos, L.L.; Miranda-Gonçalves, V.; Morais, A.; Amaro, T.; Longatto-Filho, A.; Baltazar, F.. "CD147 and MCT1-potential partners in bladder cancer aggressiveness and cisplatin resistance". Molecular Carcinogenesis 54 11 (2015): 1451-1466. http://www.scopus.com/inward/record.url?eid=2-s2.0-84945189106&partnerID=MN8TOARS.
    10.1002/mc.22222
  47. Morais-Santos, F.; Granja, S.; Miranda-Gonçalves, V.; Moreira, A.H.J.; Queirós, S.; Vilaça, J.L.; Schmitt, F.C.; et al. "Targeting lactate transport suppresses in vivo breast tumour growth". Oncotarget 6 22 (2015): 19177-19189. http://www.scopus.com/inward/record.url?eid=2-s2.0-84938895687&partnerID=MN8TOARS.
    10.18632/oncotarget.3910
  48. Silva-Carvalho, R.; Miranda-Gonçalves, V.; Ferreira, A.M.; Cardoso, S.M.; Sobral, A.J.F.N.; Almeida-Aguiar, C.; Baltazar, F.. "Antitumoural and antiangiogenic activity of Portuguese propolis in in vitro and in vivo models". Journal of Functional Foods 11 C (2014): 160-171. http://www.scopus.com/inward/record.url?eid=2-s2.0-84926359911&partnerID=MN8TOARS.
    10.1016/j.jff.2014.09.009
  49. Morais-Santos, F.; Miranda-Gonçalves, V.; Pinheiro, S.; Vieira, A.F.; Paredes, J.; Schmitt, F.C.; Baltazar, F.; Pinheiro, C.. "Differential sensitivities to lactate transport inhibitors of breast cancer cell lines". Endocrine-Related Cancer 21 1 (2014): 27-38. http://www.scopus.com/inward/record.url?eid=2-s2.0-84893558970&partnerID=MN8TOARS.
    10.1530/ERC-13-0132
  50. Valença, I.; Morais-Santos, F.; Miranda-Gonçalves, V.; Ferreira, A.M.; Almeida-Aguiar, C.; Baltazar, F.. "Portuguese propolis disturbs glycolytic metabolism of human colorectal cancer in vitro". BMC Complementary and Alternative Medicine 13 (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84880334946&partnerID=MN8TOARS.
    10.1186/1472-6882-13-184
  51. Martinho, O.; Silva-Oliveira, R.; Miranda-Gonçalves, V.; Clara, C.; Almeida, J.R.; Carvalho, A.L.; Barata, J.T.; Reis, R.M.. "In vitro and in vivo analysis of RTK inhibitor efficacy and identification of its novel targets in glioblastomas". Translational Oncology 6 2 (2013): 187-196. http://www.scopus.com/inward/record.url?eid=2-s2.0-84875783182&partnerID=MN8TOARS.
    10.1593/tlo.12400
  52. Miranda-Gonçalves, V.; Honavar, M.; Pinheiro, C.; Martinho, O.; Pires, M.M.; Cordeiro, M.; Bebiano, G.; et al. "Monocarboxylate transporters (MCTs) in gliomas: Expression and exploitation as therapeutic targets". Neuro-Oncology 15 2 (2013): 172-188. http://www.scopus.com/inward/record.url?eid=2-s2.0-84875731196&partnerID=MN8TOARS.
    10.1093/neuonc/nos298
  53. Granja, S.; Morais-Santos, F.; Miranda-Gonçalves, V.; Viana-Ferreira, M.; Nogueira, R.; Nogueira-Silva, C.; Correia-Pinto, J.; Baltazar, F.. "The monocarboxylate transporter inhibitor a-cyano-4-hydroxycinnamic acid disrupts rat lung branching". Cellular Physiology and Biochemistry 32 6 (2013): 1845-1856. http://www.scopus.com/inward/record.url?eid=2-s2.0-84890530426&partnerID=MN8TOARS.
    10.1159/000356617
  54. Martinho, O.; Pinto, F.; Granja, S.; Miranda-Gonçalves, V.; Moreira, M.A.R.; Ribeiro, L.F.J.; di Loreto, C.; et al. "RKIP Inhibition in Cervical Cancer Is Associated with Higher Tumor Aggressive Behavior and Resistance to Cisplatin Therapy". PLoS ONE 8 3 (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84875122880&partnerID=MN8TOARS.
    10.1371/journal.pone.0059104
  55. Martinho, O.; Granja, S.; Jaraquemada, T.; Caeiro, C.; Miranda-Gonçalves, V.; Honavar, M.; Costa, P.; et al. "Downregulation of RKIP is associated with poor outcome and malignant progression in gliomas". PLoS ONE 7 1 (2012): http://www.scopus.com/inward/record.url?eid=2-s2.0-84856088642&partnerID=MN8TOARS.
    10.1371/journal.pone.0030769
  56. Silva-Correia, J.; Miranda-Gonçalves, V.; Salgado, A.J.; Sousa, N.; Oliveira, J.M.; Reis, R.M.; Reis, R.L.. "Angiogenic potential of gellan-gum-based hydrogels for application in nucleus pulposus regeneration: In vivo study". Tissue Engineering - Part A 18 11-12 (2012): 1203-1212. http://www.scopus.com/inward/record.url?eid=2-s2.0-84861820964&partnerID=MN8TOARS.
    10.1089/ten.tea.2011.0632
  57. Pértega-Gomes, N.; Vizcaíno, J.R.; Miranda-Gonçalves, V.; Pinheiro, C.; Silva, J.; Pereira, H.; Monteiro, P.; et al. "Monocarboxylate transporter 4 (MCT4) and CD147 overexpression is associated with poor prognosis in prostate cancer". BMC Cancer 11 (2011): http://www.scopus.com/inward/record.url?eid=2-s2.0-79960587072&partnerID=MN8TOARS.
    10.1186/1471-2407-11-312
Thesis / Dissertation
  1. Baltazar, Fátima; Reis, R. M.; Gonçalves, Vera Mónica Miranda. "Monocarboxylate Transporters in gliomas: regulation and therapeutic implications". PhD, 2016. http://hdl.handle.net/1822/45259.
  2. Baltazar, Fátima; Reis, R. M.; Gonçalves, Vera Mónica Miranda. "Role of monocarboxylate transporters in the metabolic remodelling of glioblastomas". Master, Universidade do Minho Escola de Medicina, 2012. http://hdl.handle.net/1822/24445.

Other

Other output
  1. Tumor growth suppression induced by biomimetic silk fibroin hydrogels. Protein-based hydrogels with distinct conformations which enable encapsulation or differentiation of cells are of great interest in 3D cancer research models. Conformational changes may cause macroscopic shifts in the hydrogels, allowing for its use as biosensors and drug carriers. In depth knowledge on how 3D conformational changes in proteins may affect cell fate and tumor formation is required.. 2016. Leping, Yan; Silva-Correia, Joana; Ribeiro, Viviana Pinto; Gonçalves, Vera Mónica Miranda; Correia, Cristina; Morais, Alain José Silva; Sousa, Rui A.; et al. http://hdl.handle.net/1822/42482.
    10.1038/srep31037
  2. Monocarboxylate transport inhibition potentiates the cytotoxic effect of 5-fluorouracil in colorectal cancer cells. Cancer cells rely mostly on glycolysis to meet their energetic demands, producing large amounts of lactate that are extruded to the tumour microenvironment by monocarboxylate transporters (MCTs). The role of MCTs in the survival of colorectal cancer (CRC) cells is scarce and poorly understood. In this study, we aimed to better understand this issue and exploit these transporters as novel therapeut. 2015. Amorim, Ricardo; Pinheiro, Céline; Gonçalves, Vera Mónica Miranda; Pereira, Helena; Moyer, Mary P.; Preto, Ana; Baltazar, Fátima. http://hdl.handle.net/1822/40241.
    10.1016/j.canlet.2015.05.015
  3. Targeting lactate transport suppresses in vivo breast tumour growth. Background: Most cancers, including breast cancer, have high rates of glucose consumption, associated with lactate production, a process referred as “Warburg effect”. Acidification of the tumour microenvironment by lactate extrusion, performed by lactate transporters (MCTs), is associated with higher cell proliferation, migration, invasion, angiogenesis and increased cell survival. Previously, we. 2015. Morais-Santos, Filipa; Granja, Sara; Miranda-Gonçalves, Vera; Moreira, António H.J.; Queirós, Sandro; Vilaça, João L.; Schmitt, Fernando C.; et al. http://hdl.handle.net/11110/997.
  4. Antitumoral and antiangiogenic activity of Portuguese propolis in in vitro and in vivo models. Propolis, a natural product, has important biological properties, however, studies with Portuguese propolis are scarce. Thus, we aimed to characterize the chemical composition and the antitumoural and antiangiogenic activities of a sample from Pereiro (Portugal). The chemical profile of our propolis sample (P10.EE) is similar to the poplar propolis type. P10.EE decreased cell viability of differen. 2014. Carvalho, Ricardo Silva; Gonçalves, Vera Mónica Miranda; Ferreira, Ana Margarida; Cardoso, Susana M.; Sobral, Abílio J. F. N.; Aguiar, Cristina; Baltazar, Fátima. http://hdl.handle.net/1822/31677.
    10.1016/j.jff.2014.09.009
  5. Portuguese propolis disturbs glycolytic metabolism of human colorectal cancer in vitro. Propolis is a resin collected by bees from plant buds and exudates, which is further processed through the activity of bee enzymes. Propolis has been shown to possess many biological and pharmacological properties, such as antimicrobial, antioxidant, immunostimulant and antitumor activities. Due to this bioactivity profile, this resin can become an alternative, economic and safe source of natural. 2013. Santos, Luísa Filipa Morais dos; Gonçalves, Vera Mónica Miranda; Baltazar, Fátima; Valença, Isabel; Ferreira, Ana Margarida; Aguiar, Cristina. http://hdl.handle.net/1822/28150.
    10.1186/1472-6882-13-184
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2024/09/10 Unveiling the circadian rhythm's influence on prostate cancer radiotherapy response 48th European Radiation Research Society Meeting
(Aveiro, Portugal)
2024/05/09 Epigenetic Radiosensitizing Approaches in Prostate Cancer Therapy: Bridging Bench to Bedside IPO PORTO SUMMIT
Portuguese Oncology Institute of Porto (IPO-Porto) (Porto, Portugal)
2024/04/29 Lactate in the epigenetic landscape recoding: towards new therapeutic strategies in renal cell carcinoma. 6th ASPIC International Congress
ASPIC (Faro, Portugal)
2023/11/09 Decoding the Metabolic-Epigenetic Rewiring in Renal Cell Carcinoma: Towards New Therapeutic Strategies 1st Young Researchers Day
Portuguese Oncology Institute of Porto (IPO-Porto) (Porto, Portugal)
2021/09/21 Unraveling the role of m6A writer complex VIRMA in Germ Cell Tumors progression EPITRAN European Epitranscriptomics Network
COST European Cooperation in Sciences & Technology (Trento, Italy)
2019/10 Metabolic reprogramming and epigenetic landscape: an interplay to renal cell carcinoma aggressiveness promotion The 26th Meeting of the EAU Section of Urological Research (ESUR)
(Porto, Portugal)
2019/10 Epigenetic-Metabolic interplay in renal cell carcinoma: role of lactate on sirtuin’s modulation ISCaM2019, 6th Anual Meeting: Cancer Metabolic Rewiring
International Society of Cancer Metabolism (ISCaM) (Braga, Portugal)
2019 Impact of lactate exposure in renal cell carcinoma aggressiveness: role of sirtuin's modulation 12º edição do IJUP
(Porto, Portugal)
2019 Role of JmjC-KDMs in HIF-1alpha-dependent modulation: Effect on esophageal squamous cell carcinoma radioresistance 12º edição IJUP
(Porto, Portugal)
2016 Monocarboxylate transporter 1 (MCT1) in glioblastoma: prognostic value and exploitation as therapeutic target XIX National Congress of Biochemistry
(Guimarães, Portugal)
2015 MCT1 plasma membrane expression as a mediator of cellular aggressiveness at hypoxic regions inglioblastomas 2nd ISCaM meeting- Metabolism and Microenvironment in cancer plasticity
International Society of Cancer Metabolism (ISCaM) (Venice, Italy)
2013 Development of Anatomical Silk/Methacrylated Gellan Gum Scaffolds for Controlling Segmental Vascularization in Meniscus Tissue Regeneration TERMIS-EU
(Istanbul, Turkey)
2013 Novel Silk-based Scaffolds for Meniscus Tissue Engineering: The Relevance of Controlling Segmental Vascularization by Methacrylated Gellan gum Hydrogels 14th EFORT Congress
(Istanbul, Turkey)
2012 Novas matrizes de seda para Engenharia de Tecidos do Menisco: A importância do controlo da neovascularização com Hidrogéis de Goma Gelana Metacrilada XXXII Congress of the Portuguese Society of Orthopaedics and Traumatology
(Vila Moura, Portugal)
2012 Functionalized gellan gum hydrogels for intervertebral disc regeneration: In vitro and in vivo studies 9th World Biomaterials Congress
(Chengdu, China)
2011 Effectiveness of receptor tyrosine kinase (RTKs) targeted therapies in glioblastomas International Society of Oncology and Biomarkers (ISOBM)
(Florence, Italy)
2009 Prostate Cancer: Metabolism and Monocarboxylate transporters (MCTs) IV Young European Scientist Meeting
(Porto, Portugal)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2023/12 - Current Probing the Molecular Interplay of Epigenetics and Metabolism to Overcome Radioresistance in Prostate Cancer
Supervisor
 PhD in Pathology and Molecular Genetics (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2023/09 - Current The interplay between epigenetics and metabolism in sarcomatoid Renal Cell Carcinoma: A novel era for biomarkers?
Supervisor
 MSc in Oncology (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2023/09 - Current CIRCA-PREDICT: Epigenetic Insights into Chronotype-Integrated Radiotherapy for Prostate CAncer - PREDICting the Impact on Efficacy and Toxicity of Treatment Timing with Circadian Rhythms
Supervisor
 MSc in Oncology (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2020/09 - Current Epitranscriptomic alterations within renal cancer metabolism reprogramming: uncovering new therapeutic targets
Co-supervisor
 Pathology and Molecular Genetics (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2021 - 2022 The Role of VHL/HIF axis-dependent metabolic profile in clear cell renal cell carcinoma aggressiveness
Supervisor
 Master in Oncology (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2019/09 - 2020/11 Anti-neoplastic effect of MLo1302 in Testicular Germ Cell Tumors: comparison with classical differentiating and demethylating agents, ATRA and DAC
Co-supervisor
 Master In Oncology (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2020/03 - 2020/06 Metabolic characterization of testicular tumours: a role of epigenetic landscape
Supervisor
 Curricular traineeship in Biochemistry (Degree)
Universidade do Porto Faculdade de Ciências, Portugal
2017 - 2018 Interplay between Warburg effect and epigenetic mechanisms in kidney cancer
Co-supervisor
 Master in Oncology (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2017 - 2018 Esophageal cancer therapy response: role of hypoxia in epigenetic mechanism regulation
Co-supervisor
 Master in Oncology (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2017 - 2018 Monocarboxylate Transporters (MCTs) in kidney cancer: the role of epigenetic mechanisms
Co-supervisor
 Master in oncology (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2015 - 2015 Metabolic alterations in bevacizumab treated glioblastoma cells
Co-supervisor
 Curricular traineeship in Biochemistry (Degree)
Universidade do Minho Escola de Ciências, Portugal
2014 - 2014 Characterization of glycolytic metabolic protein expressions in melanomas
Co-supervisor
 Integrated Master in Medicine (Master)
Universidade do Minho Escola de Medicina, Portugal

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2024/12/09 BIOFABRICATION OF 3D TUMOR MODELS FOR IN VITRO SCREENING OF THERAPEUTICS
(Thesis) Arguer
 Inês Margarida Curioso Freitas (Master)
Universidade de Aveiro, Portugal
2024/11/15 "Biomarcadores de prognóstico e potenciais alvos terapêuticos no carcinoma epidermóide da orofaringe"
(Thesis) Arguer
 Ana Isabel Pereira Rodrigues (Master)
Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
2023/12 Dissecting the roles of the Aryl Hydrocarbon Receptor from a sensor to a regulator of the melanoma microenvironment
(Thesis) Main arguer
 Beatriz Gandra Moreira (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2023/07 O papel da CD147 na imunossupressão tumoral
(Thesis) Main arguer
 Ana Teresa Moreira Leal (Other)
Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
2022/12/09 The role of hypoxia on immunomodulation at the colon cancer microenvironment
(Thesis) Main arguer
 Ana Rita Fialho dos Santos (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2022/11/29 O papel do GPR81 no cancro de pulmão de não pequenas células
(Thesis) Main arguer
 Ana Margarida Ribeiro Silva (Master)
Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
2022/11/25 Estudo do Efeito da Berberina em Cancro da Próstata: o Papel da SMYD3
(Thesis) Main arguer
 Maria João Ribeiro Oliveria (Master)
Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
2022/11/25 The role of VHL/HIF axis-dependent metabolic profile in clear cell renal cell carcinoma aggressiveness
Supervisor
 Ana Beatriz Ferreira Costa (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2022/02/16 GPR81 in Bladder Cancer - Functional Insights
(Thesis) Main arguer
 Ana Mafalda Azevedo Félix (Master)
Universidade do Minho Escola de Medicina, Portugal
2021/03 Embryonic T-box transcription factor Brachyury as a predictive biomarker and therapeutic target in prostate and lung cancer
(Thesis) Main arguer
 Patricia Fernandes Fontão (Master)
Universidade do Minho Escola de Ciências, Portugal
2019/12/16 Prostate cancer cells metabolism on the interplay of androgenic regulation and metabolic environment
(Thesis) Arguer
 Henrique José Matos Morão Mingote Cardoso (PhD)
Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2018 Interplay between Warburg effect and epigenetic mechanisms in kidney cancer
Supervisor
 Ana Lameirinhas (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Ad Hoc journal article review

Journal title (ISSN) Publisher
2021 - Current Journal of Translational Medicine BMC journal
2019 - Current Clinical Epigenetics BMC Journal
2019 - Current Theranostics
2019 - Current Cancers MDPI

Association member

Society Organization name Role
2014 - Current Portuguese Association of Cancer Research (ASPIC)
2014 - Current European Association for Cancer Research (EACR)
2011 - Current International Society for Cancer Metabolism (ISCaM)
2010 - Current Sociedade Portuguesa de Bioquimica
2009 - Current Neuro-Oncology Portuguese Association (APNO)

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2024/10 - 2024/11 Lecture " CAM assay" from curricular unit Experimental Cancerization from MSc program in Oncology (Mestrado) Universidade do Porto Faculdade de Medicina, Portugal
2024/10 - 2024/11 Lecture “In vivo experimental models: chicken chorioallantoic membrane (CAM) assay”, curricular unit Oncobiology, MSc in Biochemistry and MSc in Bioengineering of Faculty of Sciences, University of Porto (FCUP) and Faculty of Engineering, University of Porto (FEUP) MSc in Biochemistry/ MSc in Bioengineering (Mestrado) Universidade do Porto Faculdade de Ciências, Portugal

Universidade do Porto Faculdade de Engenharia, Portugal
2023/10 - 2024/10 Lecture Class "Epigenetics & Cancer Metabolism", curricular unit Epigenetics from MSc in Oncology MSc in Oncology (Mestrado) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2024/05 - 2024/05 “Confocal Microscopy: 3D reconstruction imaging” and “In vitro and In vivo Experimental Models of Radiotherapy”, Curricular Unit Research Practices in Oncology, Institute of Biomedical Sciences Abel Salazar, University of Porto (ICBAS-UP). MSc in Oncology (Mestrado) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2023/10 - 2023/10 Lecture "Fundamentals of Chicken Chorioallantoic Membrane (CAM) Assay" of curricular unit Experimental Cancerization from MSc program in Oncology MSc in Oncology (Mestrado) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2023/03/27 - 2023/07/28 Oncobiology Medicinal Biotechnology (Licenciatura) Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
2023/03/27 - 2023/07/28 Oncobiology Biomedical Laboratory Sciences (Licenciatura) Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
2023/04 - 2023/04 Lecture Class "Epigenetics & Cancer Metabolism", curricular unit Epigenetics from MSc in Oncology MSc in Oncology (Mestrado) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2023/03 - 2023/03 Lecture classe on" Epigenetics and cancer Metabolism" of curricular unit Cancer Epigenetics from PhD/MSc program in Medicine and Molecular Oncology and PhD program in Pathology & molecular Genetics MSc In Medicine and Molecular Oncology (Mestrado) Universidade do Porto Faculdade de Medicina, Portugal
2022/04 - 2022/04 Lecture Class "Epigenetics & Cancer Metabolism", curricular unit Epigenetics from MSc in Oncology MSc in Oncology (Mestrado) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2022/02/07 - 2022/02/07 Lecture classe on" Epigenetics and cancer Metabolism" of curricular unit Cancer Epigenetics from PhD/MSc program in Medicine and Molecular Oncology and PhD program in Pathology & molecular Genetics Master in Medicine and Molecular Oncology (Mestrado) Universidade do Porto Faculdade de Medicina, Portugal
2022 - 2022 Lecture "Fundamentals of Chicken Chorioallantoic Membrane (CAM) Assay" of curricular unit Experimental Cancerization from MSc program in Oncology MSc in Oncology (Mestrado) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2021/10/28 - 2021/10/28 Lecture "Fundamentals of Chicken Chorioallantoic Membrane (CAM) Assay" of curricular unit Experimental Cancerization from MSc program in Oncology Master Degree in Oncology (Mestrado) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2021/04/27 - 2021/04/27 Lecture classe on" Epigenetics and cancer Metabolism" of curricular unit Epigenetics from MSc program in Oncology Master Degree in Oncology (Mestrado) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2021/02/08 - 2021/02/08 Lecture classe on" Epigenetics and cancer Metabolism" of curricular unit Cancer Epigenetics from PhD/MSc program in Medicine and Molecular Oncology and PhD program in Pathology & molecular Genetics MSc in Medicine and Molecular Oncology (Mestrado) Universidade do Porto Faculdade de Medicina, Portugal
2020/11/03 - 2020/11/24 Lecture "Fundamentals of Chicken Chorioallantoic Membrane (CAM) Assay" of curricular unit Experimental Cancerization from MSc program in Oncology Master in Oncology (Mestrado) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2020/11 - 2020/11 Lecture "Cell culture" class in Introduction to Research Activity CI-IPOP Training Course (Outros) Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal
2020/02/03 - 2020/02/20 Lecture classe on" Epigenetics and cancer Metabolism" of curricular unit Cancer Epigenetics from PhD/MSc program in Medicine and Molecular Oncology and PhD program in Pathology & molecular Genetics MSc in Medicine and Molecular Oncology (Mestrado)
2019/10/21 - 2019/11/01 Co-organization and Lecture of Basic cell culture course, 5th edition Basic course of cell culture (Outros) Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal
2019/09/17 - 2019/10/17 Lecture "Cell culture" class in Introduction to Research Activity CI-IPOP Training Course (Outros) Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal
2019 - 2019 Lecture classe on" Epigenetics and cancer Metabolism" of curricular unit Cancer Epigenetics from PhD/MSc program in Medicine and Molecular Oncology and PhD program in Pathology & molecular Genetics (Outros) Universidade do Porto, Portugal
2019 - 2019 Lecture in "Epigenetics and Cancer Metabolism" of curricular unit Epigenetics Master in Oncology (Mestrado) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2018/10/01 - 2018/10/13 Co-organization and Lecture of Basic cell culture course, 4th edition Basic course of cell culture (Outros) Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal
2018 - 2018 Lecture classe on "Epigenetics and Cancer Metabolism" of curricular unit Cancer Epigenetics from PhD/MSc program in Medicine and Molecular Oncology (Outros) Universidade do Porto Faculdade de Medicina, Portugal
2017/09/04 - 2017/09/09 Co-organization and Lecture of Basic cell culture course, 3rd edition Basic course of cell culture (Outros) Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal
2017/05/08 - 2017/05/20 Co-organization and Lecture of Basic cell culture course, 2nd edition Basic course of cell culture (Outros) Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal
2015/11/09 - 2015/11/20 Lecture of pratical classes in Fundamentals in Genetic, Development and Neoplasia course, 7th edition (Mestrado) Universidade do Minho Escola de Medicina, Portugal
2014/10/13 - 2014/10/20 Lecture of pratical classes in Fundamentals in Genetic, Development and Neoplasia course, 6th edition (Mestrado) Universidade do Minho Escola de Medicina, Portugal

Mentoring / Tutoring

Topic Student name
2023/03 - 2023/06 Tumor metabolism and prostate cancer radioresistance Rúben Diogo Oliveira de Sousa
2023/03 - 2023/06 Sarcomatoid methylation profile Fernanda Pontes
2021/02/22 - 2021/06/23 Laboratory Practice / Clinical Practice of the Master's Degree in Oncology Ana Beatriz Ferreira Costa
2019/02/11 - 2019/06/07 Laboratory Practice / Clinical Practice of the Master's Degree in Oncology Ana Rita Cardoso
Distinctions

Award

2024 2º award in a poster presentation, “Impacto do horário do tratamento de radioterapia nos resultados oncológicos em pacientes com adenocarcinoma da próstata localizado: um estudo clínico observacional retrospetivo português".
Liga Portuguesa Contra o Cancro Núcleo Regional do Norte, Portugal
2024 1º award in oral communication, “Reprogramação metabólica e ativação imunológica no carcinoma renal: papel do FTO e potencial terapêutico do inibidor DAC51”
Liga Portuguesa Contra o Cancro Núcleo Regional do Norte, Portugal
2023 1º award in a poster presentation: "Epigenetic reprogramming as Hallmark of prostate cancer radiobiology".
Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
2017 Prémio Professor Manuel Teixeira Silva
Universidade do Minho Escola de Medicina, Portugal
2009 2º award in oral communication : "Prostate Cancer: Metabolism and Monocarboxylate Transporters (MCTs)"
IV Young European Scientist Meeting, Portugal