Ana Teresa de Carvalho Negrão Serra (8F1C-DF07-1C9E)

Curriculum Vitae

Ana Teresa de Carvalho Negrão Serra

I got my PhD in Engineering and Technology Sciences (2010/03) from ITQB-NOVA. My PhD was done in Nutraceuticals and Controlled Delivery (NCD) Lab iBET/ITQB-NOVA, and focused on the development of functional ingredients derived from apples and cherries using novel extraction technologies and phytochemical/bioactivity assays. Part of my studies were done at Univ Coimbra (H. de Sousa Lab) where I acquired experience in supercritical fluid extraction methodologies. The work developed was innovative as for the first time the potential of apple and cherry Portuguese varieties to be use as natural ingredients for the development of novel foods was demonstrated. Part of the work was published in a book (ISBN:978-972-9937-2-1). In 2010/04, I secured a research contract from iBET to grow a team on Natural Compounds Bioactivity. Our research combined green extraction processes with cell-based assays aiming to develop functional ingredients derived from industry by-products/residues. This work attracted private funding from industry (Sumol+Compal SA, Grupo Amorim, Aveleda) to foster the valorization of key industry wastes in the food and cosmetic fields. The impact and innovative nature of our research was attested by 3 competitive awards received: Nutrition Awards-2011, -2012 and Aveleda Award-2013. My strong interest in cell-based models led me to undertake a 1yr post-doc internship at ACTU of iBET (2014), where I gained knowledge on human cancer stem cells biology and bioprocessing. The project was developed in close collaboration with Merck Serono and provided me strong management skills and scientific competences to develop new advanced models of colorectal cancer for the evaluation of food bioactives and excel this thematic line in my research career path. In 2015, I became a PI of research projects of iNOVA4Health program where, in collaboration with clinical partners (IPOLFG, NMS), we aimed at understanding the molecular mechanisms underlying the anticancer effect of natural bioactive compounds and potentiate the clinical translation of our research. I carried out a visiting stay at Foodomics Lab at CIAL (Spain) in 2015/05, to acquired expertise in foodomics tools to support the identification of the food constituents and nutrients at the molecular level and perform synergistic studies. In 2018/04, I established my group in the Food Functionality and Bioactives Lab at iBET. Our activities focused on the implementation of robust bioassays platforms and human intervention studies for the evaluation of the health benefits of novel foods/ingredients, under the scope of research contracts with industry (Sovena, Vitacress,Buggypower), in collaboration with clinicians (NMS, IPOLFG) and nutritionist (T. Bohn, LIH Luxemburg). In 2019/02, I started my position as Auxiliary Investigator of iBET with a competitive EEC contract awarded by FCT. In 2021/04 I became the Head of the Natural Bioactives and Nutraceuticals (NB&N) Area at iBET, coordinating the activities of 3 Labs: NB&N-chemical characterization, NB&N-process technologies, NB&N-functionality. Since 2022, I have been an invited Scientist at UFSM in Brazil. To support my research I secured, as PI/co-PI, funding from FCT, PRIMA, EEA Grants, and internal funds (726K€). The integrative nature of my expertise has been essential in other iBET research projects funded by FCT, EU and industry (850K€) and since 2021/08 we have been participating in the agenda VIIAFOOD, funded by PRR (1.8M€). I lead a team of 2 Scientists, 2 Post-Docs, 8 PhD and 2 MSc students, 4 junior research fellows and 1 Senior Technician. I completed the supervision of 13 MSc students and 4 Post-Docs and I am lecturer in PhD and MSc Programs (ITQB-NOVA, FFUL). I published 71 manuscripts (total citations:2372; h-index:30), 7 book chapters and presented over 100 posters and 40 oral communications (16 invited), demonstrating the scientific competences, originality and international recognition of my research

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Identification

Personal identification

Full name: Ana Teresa de Carvalho Negrão Serra

Citation names

Ana Teresa Serra

Author identifiers

Ciência ID: 8F1C-DF07-1C9E
ORCID iD: 0000-0002-8618-8299

Languages

Language	Speaking	Reading	Writing	Listening	Peer-review
English	Proficiency (C2)	Proficiency (C2)	Proficiency (C2)	Proficiency (C2)
French	Intermediate (B1)	Advanced (C1)	Intermediate (B1)	Intermediate (B1)

Education

	Degree	Classification
2010/03/18 Concluded	Engineering Sciences and Technology - Biotechnology (Doutoramento) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal "Valorization of Traditional Portuguese Apples and Cherries- Biochemical characterization and development of functional ingredients" (THESIS/DISSERTATION)	Aprovada por unanimidade
2007/06/30 Concluded	Curso de Actualização em Nutracêuticos e Medicamentos à Base de Plantas (Pós-Graduação) Universidade de Lisboa Faculdade de Farmácia, Portugal "-" (THESIS/DISSERTATION)	14 valores
2003 Concluded	Engenharia Biológica (Licenciatura) Universidade de Lisboa Instituto Superior Técnico, Portugal "n/a" (THESIS/DISSERTATION)	15 valores
1998 Concluded	n/a (Ensino secundário) Escola Secundária Nº2 da Portela, Portugal "n/a" (THESIS/DISSERTATION)	17 valores

Affiliation

Science

	Category Host institution	Employer
2019/02/01 - Current	Auxiliary Researcher (Research)	Instituto de Biologia Experimental e Tecnológica, Portugal
	Instituto de Biologia Experimental e Tecnológica, Portugal
2022/05/01 - 2022/05/15	Visiting Researcher (Research)	Instituto de Biologia Experimental e Tecnológica, Portugal
	Universidade Federal de Santa Maria, Brazil
2015/07/01 - 2019/01/31	Contracted Researcher (Research)	Instituto de Biologia Experimental e Tecnológica, Portugal
	Instituto de Biologia Experimental e Tecnológica, Portugal
2010/04/01 - 2015/06/30	Postdoc (Research)	Instituto de Biologia Experimental e Tecnológica, Portugal

2015/05/01 - 2015/05/18	Visiting Researcher (Research)	Instituto de Biologia Experimental e Tecnológica, Portugal
	Instituto de Investigación en Ciencias de la Alimentación, Spain
2008/11/01 - 2008/12/22	Visiting Researcher (Research)	Instituto de Biologia Experimental e Tecnológica, Portugal
	Universidade de Coimbra, Portugal
2004/05/01 - 2005/01/31	Research Trainee (Research)	Instituto de Biologia Experimental e Tecnológica, Portugal

Positions / Appointments

	Category Host institution	Employer
2021/04/01 - Current	Coordenadora de área - Natural Bioactives & Nutraceuticals; Responsável de laboratório NB&N Functionality	Instituto de Biologia Experimental e Tecnológica, Portugal
	Instituto de Biologia Experimental e Tecnológica, Portugal

Others

	Category Host institution	Employer
2005/02/01 - 2010/03/31	PhD student ((with a FCT funding grant - SRFH/BD/19238/2004))	Instituto de Biologia Experimental e Tecnológica, Portugal

2003/03/01 - 2003/09/30	Trainee	Nacional, Cerealis, Portugal

Projects

Grant

	Designation	Funders
2023/01/01 - 2026/12/31	From Sea to Skin: Unveiling the potential of marine microalgae, actinobacteria and halophyte plants to develop high added value ingredients for cosmeceuticals applications 2022.13380.BD Supervisor Instituto de Biologia Experimental e Tecnológica, Portugal	Ongoing
2022/01/20 - 2025/12/31	Development of antimicrobial hydrogels based on bacterial cellulose and rhamnolipids 2021.05798.BD co-orientador Instituto de Biologia Experimental e Tecnológica, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2022/01/01 - 2025/12/31	O-live: Virgin Olive oiL as a potential hIgh-Value food ingredient towards colorectal cancer thErapy 2021.07620.BD Supervisor Instituto de Biologia Experimental e Tecnológica, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2022/01/01 - 2025/12/31	SaffronSkin: Unravelling the cosmeceutical potential of saffron phytochemicals 2021.08117.BD Supervisor Instituto de Biologia Experimental e Tecnológica, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2022/01/01 - 2025/12/31	Development of polymeric dressings for advanced wound care based on natural polysaccharides: bacterial cellulose, FucoPol and chitin-glucan complex 2021.05014.BD co-orientador Instituto de Biologia Experimental e Tecnológica, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2021/09/01 - 2024/01/31	Adding value to chicory roots: evaluation of anti-inflammatory potential of terpenes for application in Inflammatory Bowel Diseases SFRH/BD/145551/2019 co-orientador Instituto de Biologia Experimental e Tecnológica, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2019/01/01 - 2021/04/30	Looking for Efficient Salt Substitute: Salicornia PI715 LessSalt Instituto de Biologia Experimental e Tecnológica, Portugal	Instituto de Biologia Experimental e Tecnológica Concluded
2005/02/01 - 2008/01/31	Valorization of traditional Portuguese apple and cherries varieties- Biochemical characterization SRFH/BD/19238/2004 PhD Student Fellow Instituto de Biologia Experimental e Tecnológica, Portugal	Fundação para a Ciência e a Tecnologia Concluded

Contract

	Designation	Funders
2010/01/01 - 2030/12/01	Development of New Functional products with application in beverage industry n.a. Researcher Instituto de Biologia Experimental e Tecnológica, Portugal	Concluded
2022/07/26 - 2025/12	Agenda VIIAFOOD - Plataforma de Valorização, Industrialização e Inovação comercial para o AgroAlimentar C644929456-00000040 Post-doc Instituto de Biologia Experimental e Tecnológica, Portugal	Agência para a Competitividade e Inovação IP Ongoing
2021/04/01 - 2025/03/31	Green technology for plant-based food NFR 319049 Post-doc Nofima AS Ås, Norway	Ongoing
2023/03/01 - 2025/02/28	Mush4Chol- Development of an efficient hypocholesterolemic formulation from mushroom bioresidues through a sustainable integrated strategy. 2022.08844.PTDC Post-doc Instituto Politécnico de Bragança, Portugal Instituto de Biologia Experimental e Tecnológica, Portugal Universidade de Trás-os-Montes e Alto Douro Centro de Investigação e de Tecnologias Agro-Ambientais e Biologicas, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2019/02 - 2025/01	Foodomics approaches to unveil the health benefits of Virgin Olive OiL towards colorectal cancer CEECIND/04801/2017 Principal investigator iNOVA4Health, Portugal Instituto de Biologia Experimental e Tecnológica, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2022/01/01 - 2024/12/31	OMICs approaches to reveal the anticancer properties of Virgin Olive Oil (VOOmics) PTDC/BAA-AGR/4732/2021 Principal investigator Instituto de Biologia Experimental e Tecnológica, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2023/05/01 - 2024/10/31	FAMAP- Faster Analytical Methodologies for Alternative Proteins iBETXplore- PI-774 Post-doc Instituto de Biologia Experimental e Tecnológica, Portugal	Ongoing
2022/01/16 - 2023/06/15	ReHalAntiOx: Recovery of antioxidant compounds from halophyte plants using green technologies: application on food and cosmetic industries EXPL/ASP-AGR/1655/2021 Post-doc Instituto de Biologia Experimental e Tecnológica, Portugal iNOVA4Health, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2021/05/01 - 2022/12/31	Chicory as a multipropose crop for dietary fibre and medicinal terpenes H2020-NMBP-2016-2017 Post-doc Instituto de Biologia Experimental e Tecnológica, Portugal	Concluded
2020/09/01 - 2022/12/31	TL3 - WP4 - New genetic variants causing increased cancer risk with impact in diagnosis and treatment LISBOA-01-0145-FEDER-007344 Principal investigator Instituto de Biologia Experimental e Tecnológica, Portugal iNOVA4Health, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2020/01/01 - 2022/12/31	ExtraSnack- Impact of the extrusion process on health-related properties of a pea and oat snack FBR_OC1_27 Co-Principal Investigator (Co-PI) Instituto de Biologia Experimental e Tecnológica, Portugal	EEA Grants Concluded
2018/10/01 - 2022/06/30	Estudo da diversidade genética de feijão-frade para uma dieta mais saudável e sustentável PTDC/BAA-AGR/29867/2017 Instituto de Biologia Experimental e Tecnológica, Portugal Instituto Nacional de Investigação Agrária e Veterinária, Portugal Universidade de Lisboa Instituto Superior de Agronomia, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2018/10/01 - 2022/06/30	COwpea (Vigna unguiculata) genetic diversity for a SUStainable HEalthy diet ALT20-03-0145-FEDER-029867	Fundação para a Ciência e a Tecnologia Ongoing
2020/10/01 - 2022/05/31	BRAVO - Evaluation of the cardiovascular protective effect of Bravo de Esmolfe apple variety in humans 742 Principal investigator Instituto de Biologia Experimental e Tecnológica, Portugal	Instituto de Biologia Experimental e Tecnológica Ongoing
2020/06/01 - 2022/05/31	TRACE-RICE- Tracing rice and valorizing side streams along Mediterranean blockchain Grant Number 1934 Researcher Instituto de Biologia Experimental e Tecnológica, Portugal	Partnership for Research and Innovation in the Mediterranean Area Ongoing
2020/06/01 - 2022/05/30	SAFFROMFOOD- Valorisation of saffron and its floral by-products as sustainable innovative sources for the development of high added-value food products ANR-18-PRIM-0016 PRIMA/0008/2018 Co-Principal Investigator (Co-PI) Instituto de Biologia Experimental e Tecnológica, Portugal	Fundação para a Ciência e a Tecnologia Partnership for Research and Innovation in the Mediterranean Area Ongoing
2020/09/01 - 2021/12/31	Muscle up with intermittent hypoxia: a matter of intensity, gender and metabolism LISBOA-01-0145-FEDER-007344 Post-doc iNOVA4Health, Portugal Instituto de Biologia Experimental e Tecnológica, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2020/02/01 - 2021/12/31	Bioplásticos e Filmes comestíveis vegan Bioplásticos e Filmes comestíveis vegan Instituto de Biologia Experimental e Tecnológica, Portugal	Concluded
2018/01/01 - 2021/12/31	Identifying Biomarkers Through Translational Research for Prevention and Stratification of Colorectal Cancer eCOST action 17118 Researcher Instituto de Biologia Experimental e Tecnológica, Portugal	Ongoing
2018/01 - 2021/12	PortASAP - European network for the promotion of portable, affordable and simple analytical platform CA 16215	N/A
2019/10/01 - 2021/09/30	CoHeSus - Cowpea (Vigna unguiculata) genetic diversity for a Sustainable Healthy diet FCT- P2020 (ALT20-03-0145-FEDER-029867) Researcher Instituto de Biologia Experimental e Tecnológica, Portugal	Ongoing
2018/04/01 - 2021/08/31	VOOmics- Omics approaches to investigate the anticancer properties of colonic metabolites derived from Virgin Olive Oil iBETXplore- Voomics Principal investigator Instituto de Biologia Experimental e Tecnológica, Portugal	Instituto de Biologia Experimental e Tecnológica Ongoing
2017/01/01 - 2020/12/31	Multi-purpose strategies for broadband agro-forest and fisheries by-products valorisation: a step forward for a truly integrated biorefinery SAICTPAC/0040/2015 SAICTPAC/0040/2015 SAICTPAC/0040/2015 - POCI-01-0145-FEDER-016403 Universidade do Minho, Portugal Universidade de Aveiro, Portugal Instituto de Biologia Experimental e Tecnológica, Portugal Universidade de Coimbra, Portugal Universidade Católica Portuguesa, Portugal Universidade Nova de Lisboa Associação para a Inovação e Desenvolvimento da FCT, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2020/10 - 2020/12	BioXosax - Characterization of xylo-oligosaccharides (XOS) and arabinoxylans (AX): new biopolymers from starch by-product for food and pharma applications iBETXplore - BioXosax Instituto de Biologia Experimental e Tecnológica, Portugal	Instituto de Biologia Experimental e Tecnológica
2019/02/01 - 2020/06	LESSsalt- Looking for efficient salt substitutes iBETXplore- Lesssalt Researcher Instituto de Biologia Experimental e Tecnológica, Portugal	Instituto de Biologia Experimental e Tecnológica Ongoing
2018/01/01 - 2020/03/31	Efficacy of olive oil and phenolic compounds in reversing hypertension induced by chronic intermittent hypoxia LISBOA-01-0145-FEDER-007344 Researcher iNOVA4Health, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2018/01/01 - 2020/03/31	The effect of olive oil compounds in the prevention of UV-induced melanogenesis LISBOA-01-0145-FEDER-007344 Researcher iNOVA4Health, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2016/01/01 - 2019/12/31	POSITIVe : Interindividual variation in response to consumption of plant food bioactives and determinants involved FA 1403 Researcher Instituto de Biologia Experimental e Tecnológica, Portugal	Concluded
2017/03/01 - 2019/02/28	MultiBioRefinery: Multi-purpose strategies for broadband agro-forest and fisheries by-products valorisation: a step forward for a truly integrated biorefinery SAICTPAC/0040/2015 Universidade do Minho, Portugal Universidade de Aveiro, Portugal Instituto de Biologia Experimental e Tecnológica, Portugal Universidade de Coimbra, Portugal Universidade Católica Portuguesa, Portugal Universidade Nova de Lisboa Associação para a Inovação e Desenvolvimento da FCT, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2016/01/01 - 2018/03/31	Molecular profiling and novel targeted therapies in thyroid and colorectal cancers LISBOA-01-0145-FEDER-007344 Principal investigator Instituto de Biologia Experimental e Tecnológica, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2015/07/01 - 2018/01/31	OrangeCTherapy- Chemotherapeutic effect of citrus bioactive compounds - evaluation for targeting human colorectal cancer stem cells LISBOA-01-0145-FEDER-007344 Principal investigator Instituto de Biologia Experimental e Tecnológica, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2015/07/01 - 2018/01/31	Novel Noninvasive Markers of Non-alcoholic Fatty liver disease Progression and Newly Therapeutic Approaches LISBOA-01-0145-FEDER-007344 Researcher Instituto de Biologia Experimental e Tecnológica, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2013/01/01 - 2016/12/31	EUBis- Food waste valorisation for sustainable chemicals, materials & fuels TD1203 Researcher Instituto de Biologia Experimental e Tecnológica, Portugal	Concluded
2013/06/01 - 2015/11/30	NutraBrass - Nutracêuticos derivados de Brassicacea: Processamento a alta-pressão de vegetais cruciferos para recuperação de ingredientes biologicamente activos com efeito na saúde. PTDC/AGR-TEC/3790/2012 Instituto de Biologia Experimental e Tecnológica, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2013/06 - 2015/11	NutraBrass - Nutraceuticals from Brassicaceae: High Pressure Processing of Cruciferous food plants to recover biologically active ingredients with health promoting effects Provided by PTCRIS: 130320	Fundação para a Ciência e a Tecnologia
2011/01/01 - 2013/12/31	NUTRACork – Compostos fenólicos da cortiça: validação cosmética, avaliação alimentar e potencial nutracêutico n.a. Researcher Instituto de Biologia Experimental e Tecnológica, Portugal	Concluded
2010/02/01 - 2013/07/31	BioNIO- Ingredientes bioactivos extraídos de Opuntia spp. Valorização das plantas do Alentejo PTDC/AGR-AAM/099645/2008 Instituto de Biologia Experimental e Tecnológica, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2010/02 - 2013/07	BioNIO - Bioactive Natural Ingredients from Opuntia spp.. Valorisation of plants from Alentejo. Provided by PTCRIS: 99645	Fundação para a Ciência e a Tecnologia
2010/01/22 - 2013/01/21	Beleza e significado da cor na iluminura medieval portuguesa[Colour in medieval illuminated manuscripts :between beauty and meaning] PTDC/EAT-EAT/104930/2008 Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal Universidade Nova de Lisboa Laboratório para a Ciência da Computação e Informática, Portugal Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente, Portugal Universidade Nova de Lisboa Faculdade de Ciências Sociais e Humanas, Portugal Instituto de Biologia Experimental e Tecnológica, Portugal Universidade de Lisboa Instituto Dom Luiz, Portugal Universidade Nova de Lisboa Instituto de Estudos Medievais, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2010/01 - 2013/01	Colour in medieval illuminated manuscripts: between beauty and meaning Provided by PTCRIS: 104930 Researcher	Fundação para a Ciência e a Tecnologia Concluded
2011/01/01 - 2012/12/31	Strategic Project - LA 4 - 2011-2012 PEst-OE/EQB/LA0004/2011 Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica António Xavier, Portugal Fundação Calouste Gulbenkian, Portugal Instituto de Biologia Experimental e Tecnológica, Portugal Universidade NOVA de Lisboa NOVA Medical School, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2010/01/01 - 2012/12/31	Naturext n.a. Researcher Instituto de Biologia Experimental e Tecnológica, Portugal	Concluded
2007/04 - 2010/11	Nanoentrapment and controlled release of bioactive compounds to improve food quality and human health Provided by PTCRIS: 67194	Fundação para a Ciência e a Tecnologia
2006/01/01 - 2008/06/30	Phytochemicals and fibers in Beiras'native varieties and exotic apples and their health benefits 930/2006.09.0040012 PhD Student Fellow Instituto de Biologia Experimental e Tecnológica, Portugal	Ministério da Agricultura Florestas e Desenvolvimento Rural Concluded
2004/01/01 - 2006/12/31	Development of New Bioproducts with application in sugar industry n.a. PhD Student Fellow Instituto de Biologia Experimental e Tecnológica, Portugal	Concluded

Other

	Designation	Funders
2018/06/01 - 2021/05/31	Programa FITEC FITEC Researcher Instituto de Biologia Experimental e Tecnológica, Portugal	Agência Nacional de Inovação SA Ongoing
2017/12/01 - 2020/11/30	PRevenção da Artrite Reumatóide: Suplemento de HIdroxitirosol em AZeite refinado (PRARHITAZ) PRARHITAZ Researcher Instituto de Biologia Experimental e Tecnológica, Portugal	Fundação Amélia de Mello Sovena Grupo Medinfar Ongoing
2017/01/01 - 2019/03/31	Microalgas Marinhas- Estudo e desenvolvimento de processo sustentável integrado para valorização de biomassa algal na Researcher Instituto de Biologia Experimental e Tecnológica, Portugal	Buggypower (Portugal), Lda Concluded
2017/01/01 - 2017/12/31	Estudo do impacto de diferentes condições de processo na textura de vegetais enlatados na Researcher Instituto de Biologia Experimental e Tecnológica, Portugal	Sumol+Compal SA Concluded
2017/01/01 - 2017/12/30	Estudo da remoção de odors em óleo de colza após fritura n.a. Researcher Instituto de Biologia Experimental e Tecnológica, Portugal	Concluded
2015/01/01 - 2016/12/31	Process optimization and scale-up of a traditional fermented beverage n.a. Researcher Instituto de Biologia Experimental e Tecnológica, Portugal
2015/01/01 - 2016/12/31	Characterization and development of phytopharmaceuticals from Portuguese honey n.a. Researcher Instituto de Biologia Experimental e Tecnológica, Portugal	Concluded
2014/01/01 - 2015/12/31	Expansion of human Cancer Stem Cells in stirred tank bioreactor n.a. Researcher Instituto de Biologia Experimental e Tecnológica, Portugal	Concluded
2013/01/01 - 2015/12/31	Development and characterization of new products derived from endemic plants and fruits n.a. Researcher Instituto de Biologia Experimental e Tecnológica, Portugal	Concluded

Outputs

Publications

Book chapter	Saldanha do Carmo, Cátia; Costa, Leonor; Serra, Ana Teresa; Knutsen, Svein Halvor; Sahlstrøm, Stefan; Bronze, Maria Rosário. "Alternative protein sources". In Food Technology Disruptions, 131-174. Elsevier, 2021. Published • 10.1016/b978-0-12-821470-1.00010-0 Bronze, Maria R.; Serra, Ana Teresa; Augusti, Paula R.; Murcia, Pilar Legua; García, Francisca Hernández. "Nutritional Composition, Antioxidant Properties, and Health Benefits of Mulberry Fruits". In Asian Berries, 41-65. CRC Press, 2020. 10.1201/9780429286476-3 Serra, Ana; Sheila Alves; Professora Maria do Rosário Bronze. "Food Matrices That Improve the Oral Bioavailability of Pharmaceuticals and Nutraceuticals". In Nutraceuticals and Natural Product Pharmaceuticals. Academia Press, 2019. Published do Carmo, C.S.; Serra, A.T.; Duarte, C.M.M.. "Recovery technologies for lipophilic bioactives". 1-49. 2017. 10.1007/978-1-4939-6595-3_1 Serra, Ana; Doutora Catarina Maria Martins Duarte; Professora Maria do Rosário Bronze. "As variedades tradicionais de maçãs das Beiras e as cultivares exóticas: estudo comparativo". In Maçãs Tradicionais de Eleição. Portugal: Agro-Manual Publicações, 2009. Published Serra, Ana; Doutora Catarina Maria Martins Duarte; Professora Maria do Rosário Bronze; Rodrigo Feliciano. "A maçã na alimentação". In Maçãs Tradicionais de Eleição, edited by Agostinho de Carvalho; Doutora Catarina Maria Martins Duarte. Portugal: Agro-Manual Publicações, 2009. Published Serra, Ana; Agostinho de Carvalho; Doutora Catarina Maria Martins Duarte. "Polifenóis e actividade antioxidante em maçãs de variedades regionais e de cultivares exóticas". In Directrices voluntarias para la conservación y la utilización sostenible de variedades de los agricultores/ variedades locales. FAO, 2009.
Conference abstract	Oliveira-Alves, Sheila Cristina; ANDRADE, FÁBIO; Andreia B. Silva; Jorge Capelo; Bernardo Duarte; Isabel Caçador; Júlio Coelho; Ana Teresa Serra; Maria R. Bronze. "How drying processes affect the quality and bioactivity of halophyte plants: the case study of Salicornia ramosissima J. woods". Paper presented in XV Encontro de Química dos Alimentos, Funchal, 2021. Published Pereira, Rafaela Sofia; Oliveira-Alves, Sheila Cristina; Sandra Silva; Inês A Isidro; Cristina Albuquerque; Patrícia Gomes alves; MR Bronze; Ana Teresa Serra. "Hydroxytyrosol, a phenolic of virgin olive oil, inhibits cell proliferation and targets cancer stemness in a 3D cell model of colorectal cancer". Paper presented in ICPH (International Conference on Polyphenols and Health FSciT-2019), kobe, 2019. Published Oliveira-Alves, Sheila Cristina; Ana Teresa Serra; MR Bronze. "Phenolic acids from baru nuts target cell proliferation in a 3D cell model of colorectal cancer". Paper presented in XX EuroFoodChem Conference, Porto, 2019. Published Ana Teresa Serra; Oliveira-Alves, Sheila Cristina; Pereira, Rafaela Sofia; Joana Alves; Sandra Silva. "Effect of hydroxytyrosol and its colonic metabolites on targeting cell proliferation and stemness in a 3D cell model of colorectal cancer". Paper presented in The 6th International Conference on Food Digestion, Granada, 2019. Published Oliveira-Alves, Sheila Cristina; Ana Teresa Serra; MR Bronze. "Identification of bioactive compounds in baru (Dipteryx alata Vog) nuts: Phenolic composition, antioxidant activity and antiproliferative affect". Paper presented in 2nd Conference on Food Bioactives & Health, Lisboa, 2018. Published
Conference paper	Serra, Ana; Mario Bordalo; Doutora Catarina Maria Martins Duarte. "Recovery of antioxidant compounds from Bravo de Esmolfe apple variety using high pressure technology". Paper presented in 16th European Meeting on Supercritical Fluids, Lisbon, 2017. Serra, Ana; Carolina Pereira. "Unveiling chemotherapeutic potential of orange peels and brassica SCF extracts in human colorectal cancer cell spheroids". Paper presented in 16th European Meeting on Supercritical Fluids, Lisbon, 2017. Published Serra, Ana; Agostinho Alexandre; Doutora Catarina Maria Martins Duarte; Doutora Maria do Rosário Bronze. "Extracts from residues of Arbutus unedo distillation process obtained by SFE: antiproliferative and citotoxicity evaluation". Paper presented in 16th European Meeting on Supercritical Fluids, Lisbon, 2017. Published Serra, Ana; Liliana Rodrigues; Doutora Catarina Maria Martins Duarte. "Supercritical CO2 as a potent solvent to isolate nutraceuticals from Lavandula and Mentha species targeting cancer". Paper presented in 14th European Meeting on Supercritical Fluids., Marseille, 2014. Serra, Ana; Doutora Catarina Maria Martins Duarte. "Evaluation of antiproliferative effect and cell cycle arrest on HT29 cells of different plant-derived natural extracts- Correlation of response with composition". Paper presented in 12th International Conference on Functional Foods Ingredients and Nutraceuticals in Chronic Disease: Science and Practice, 2012. Serra, Ana; Doutora Catarina Maria Martins Duarte. "Development of bioactive natural ingredients from sweet cherry and plum wastes". Paper presented in International Symposium on Plum and Sweet Cherry, 2012. Published Serra, Ana; Doutora Catarina Maria Martins Duarte; Doutora Maria do Rosário Bronze. "Phytochemical and bioactivity characterization of nine sweet cherry varieties". Paper presented in International Symposium on Plum and Sweet Cherry, 2012. Published Serra, Ana; Doutora Catarina Maria Martins Duarte. "Development of functional ingredients from Portuguese cherries". Paper presented in XXVth International Conference on Polyphenols, 2010. Published Serra, Ana; Doutora Catarina Maria Martins Duarte. "Looking for functionality in apple cultivars- a study focused on radical scavenging and anticancer activity". Paper presented in XXIVth International Conference on Polyphenols, 2008. Published Serra, Ana; Lucelia Tavares. "Phytochemical characterization of leaf and root tissues from raspberry, including antioxidant activity evaluation". Paper presented in XXIVth International Conference on Polyphenols, 2008. Published Serra, Ana; Dina Carrilho. "Antioxidant properties and phytochemical analysis of an uncharacterized portuguese endemic aromatic herb, Thymus capitellatus.". Paper presented in XXIVth International Conference on Polyphenols, 2008. Published Serra, Ana; Cláudia Santos. "Phytochemical evaluation of Quercus species. Antioxidant properties of Q. suber leaves in neurodegeneration cell model". Paper presented in XXIVth International Conference on Polyphenols, 2008. Published Serra, Ana; Mónica Faustino; Doutora Catarina Maria Martins Duarte. "Processing cherry waste with supercritical fluids to develop a new promising nutraceutical". Paper presented in 11th European Meeting on Supercritical Fluids, 2008. Published
Conference poster	Matos, Melanie S.; Claudia Nunes dos Santos; Ana A. Matias; Ana Teresa Serra. Corresponding author: Matos, Melanie S.. "The Healing Power of Chicory: Anti-inflammatory Effect of Sesquiterpene Lactones on the Intestinal Mucosa". Paper presented in 3rd Food Chemistry Conference: Shaping a Healthy and Sustainable Food Chain through Knowledge, 2023. Leonor Teixeira da Costa; Reynolds-Brandão, P.; Ana Teresa Serra; Maria Rosario Bronze. "Phytochemical composition of 38 Algerian saffron stigma samples (Crocus sativus L.): A comparative study towards the identification of compounds with antioxidant effect". Paper presented in 13th PhD Students¿ Meeting ITQB-NOVA, 2023. Cátia Saldanha do Carmo; Mecha, Elsa; Juliana, Oliveira; Gesine Schmidt; Sara M. Gaber; Svein Halvor Knutsen; Stefan Sahlstrom; Maria Rosário Bronze; Ana Teresa Serra. "Phenolic composition of snacks based on pea protein, pea starch and an oat ß-glucan rich fraction". Paper presented in 4th International Conference on Food Bioactives and Health, 2023. Mecha, Elsa; Sheila C. Oliveira-Alves; Juliana Oliveira; Ana Teresa Serra; Maria Rosário Bronze. "When Diversity in the Halophyte Species Means Phenolic Compounds Variability". Paper presented in 4th International Conference on Food Bioactives and Health, 2023. Mecha, Elsa; Juliana Oliveira; Naiara Fernández; Ana Teresa Serra; Maria Rosário Bronze. "The double-edged sword of halophyte plants in the quality of vegetable oils.". Paper presented in 19th Euro Fed Lipid Congress and Expo, 2023. Cátia Saldanha do Carmo; Mecha, Elsa; Juliana, Oliveira; Svein Halvor Knutsen; Stefan Sahlstrom; Maria Rosário Bronze; Ana Teresa Serra. "Impact of dry-fractionation and cooking on antinutrients in yellow pea and faba bean protein fractions.". Paper presented in International symposium Dietary Protein for Human Health, 2023. Leonor Teixeira da Costa; Reynolds-Brandão, P.; Ana Teresa Serra; Maria Rosario Bronze. "PHYTOCHEMICAL CHARACTERIZATION AND VOLATILE COMPOSITION OF 38 SAFFRON (CROCUS SATIVUS L.) STIGMAS PRODUCED IN ALGERIA: IDENTIFICATION OF COMPOUNDS WITH ANTIOXIDANT EFFECT". Paper presented in 4th International Conference on Food Bioactives & Health, FBHC2023, 2023. Cátia Saldanha do Carmo; Mecha, Elsa; Juliana, Oliveira; Svein Halvor Knutsen; Stefan Sahlstrom; Maria Rosário Bronze; Ana Teresa Serra. "Impact of processing on antinutrients present in pulse protein concentrates and food products". Paper presented in Dare2Change, 2023. Cátia Saldanha do Carmo; Mecha, Elsa; Juliana, Oliveira; Gesine Schmidt; Sara M. Gaber; Svein Halvor Knutsen; Stefan Sahlstrom; Maria Rosário Bronze; Ana Teresa Serra. "Phenolic composition and antioxidant capacity of pea- and oat-based expanded snacks produced by extrusion". Paper presented in Dare2Change, 2023. Mecha, Elsa; Juliana, Oliveira; Fernández, Naiara; Ana Teresa Serra; Bronze, Maria Do Rosario. "Vegetable oil quality: the added value of halophyte plants". Paper presented in Dare2Change, 2023. Amaral, Mariana; Ana Henriques Mota; Inês Prazeres; Ana Teresa Serra; Maria Manuela Gaspar; Lia Ascensão; Ana Silveira Viana; et al. "Sambucus nigra L. extract-loaded polymeric nanoparticles as a potential anti-inflammatory topical formulation". Paper presented in Natural products application: Health, Cosmetic and Food, 2021. 10.13140/RG.2.2.24201.77922 Ana P. C. Almeida; Salima Varona; Ana Teresa Serra; Sara Beirão da Costa; Maria José Cocero; Catarina M.M. Duarte. "Impregnation of essential oils into starch-based particles using supercritical fluid technology". Paper presented in 1st Iberian Meeting on Natural Bioactives Entrapment for the Food Industry Challenges and Perspectives, from nanotechnology to bioavailability, Lisbon, Portugal, 2011.
Journal article	Verónica Weng; Martim Cardeira; Andreia Bento-Silva; Ana Teresa Serra; Carla Brazinha; Maria Rosário Bronze. "Arabinoxylan from Corn Fiber Obtained through Alkaline Extraction and Membrane Purification: Relating Bioactivities with the Phenolic Compounds". Molecules (2023): https://doi.org/10.3390/molecules28155621. 10.3390/molecules28155621 Oliveira-Alves, Sheila Cristina; ANDRADE, FÁBIO; Sousa, João; Silva, Andreia Bento; Duarte, Bernardo; Caçador, Isabel; Miguel Salazar; et al. Corresponding author: Maria do Rosario Bronze. "Soilless Cultivated Halophyte Plants: volatile, nutritional, phytochemical and biological differences". Antioxidants (2023): Manuscript ID: antioxidants-2387483. Accepted Cankar, Katarina; Hakkert, Johanna Christina; Sevenier, Robert; Papastolopoulou, Christina; Schipper, Bert; Baixinho, João P.; Fernández, Naiara; et al. "Lactucin Synthase Inactivation Boosts the Accumulation of Anti-inflammatory 8-Deoxylactucin and Its Derivatives in Chicory (Cichorium intybus L.)". Journal of Agricultural and Food Chemistry 71 15 (2023): 6061-6072. https://doi.org/10.1021/acs.jafc.2c08959. Published • 10.1021/acs.jafc.2c08959 Concórdio-Reis, Patrícia; Ramos, Kleyde; Macedo, Ana Catarina; Serra, Ana Teresa; Moppert, Xavier; Guézennec, Jean; Sevrin, Chantal; et al. "Bioactive exopolysaccharide-composites based on gold and silver nanoparticles tailored for wound healing". Materials Today Communications 34 (2023): 105351. http://dx.doi.org/10.1016/j.mtcomm.2023.105351. Published • 10.1016/j.mtcomm.2023.105351 Concórdio-Reis, Patrícia; Cardeira, Martim; Macedo, Ana Catarina; Ferreira, Sónia S.; Serra, Ana Teresa; Coimbra, Manuel A.; Amorim, Ana; Reis, Maria A.M.; Freitas, Filomena. "Novel exopolysaccharide produced by the marine dinoflagellate Heterocapsa AC210: Production, characterization, and biological properties". Algal Research 70 (2023): 103014. http://dx.doi.org/10.1016/j.algal.2023.103014. 10.1016/j.algal.2023.103014 Concórdio-Reis, Patrícia; Macedo, Ana Catarina; Cardeira, Martim; Moppert, Xavier; Guézennec, Jean; Sevrin, Chantal; Grandfils, Christian; Serra, Ana Teresa; Freitas, Filomena. "Selenium Bio-Nanocomposite Based on Alteromonas macleodii Mo169 Exopolysaccharide: Synthesis, Characterization, and In Vitro Antioxidant Activity". Bioengineering 2 (2023): https://www.mdpi.com/2306-5354/10/2/193. Open access • Published Popovic, Boris M.; Gligorijevic, Nevenka; Arandelovic, Sandra; Macedo, Ana Catarina; Juric, Tatjana; Uka, Denis; Mocko-Blažek, Karolina; Serra, Ana Teresa. "Cytotoxicity profiling of choline chloride-based natural deep eutectic solvents". RSC Advances 13 6 (2023): 3520-3527. http://dx.doi.org/10.1039/d2ra07488e. Published • 10.1039/d2ra07488e Débora Cerdá-Bernad; Leonor Costa; Ana Teresa Serra; Maria Rosário Bronze; ESTEFANÍA VALERO-CASES; Francisca Pérez-Llamas; María Emilia Candela; et al. "Saffron against Neuro-Cognitive Disorders: An Overview of Its Main Bioactive Compounds, Their Metabolic Fate and Potential Mechanisms of Neurological Protection". Nutrients (2022): https://www.mdpi.com/2072-6643/14/24/5368. 10.3390/nu14245368 Kheyar, Naoual; Bellik, Yuva; Serra, Ana Teresa; Kheyar, Farida; Bedjou, Fatiha. "Inula viscosa phenolic extract suppressescolon cancer cell proliferation and ulcerative colitisby modulating oxidative stress biomarkers". BioTechnologia 103 3 (2022): 269-281. http://dx.doi.org/10.5114/bta.2022.118670. Published • 10.5114/bta.2022.118670 Martim Cardeira; Ana Bernardo; Inês Leonardo; Frédéric B. GASPAR; Marta Marques; Rodrigo Melgosa; Alexandre Paiva; et al. "Cosmeceutical Potential of Extracts Derived from Fishery Industry Residues: Sardine Wastes and Codfish Frames". Antioxidants (2022): https://www.mdpi.com/2076-3921/11/10/1925. 10.3390/antiox11101925 Ruas, Ana; Graça, Angelica; Marto, Joana; Gonçalves, Lídia; Oliveira, Ana; da Silva, Alexandra Nogueira; Pimentel, Madalena; et al. "Chemical Characterization and Bioactivity of Commercial Essential Oils and Hydrolates Obtained from Portuguese Forest Logging and Thinning". Molecules 27 11 (2022): 3572. http://dx.doi.org/10.3390/molecules27113572. Published • 10.3390/molecules27113572 Francisca Hernández; Lucía Andreu-Coll; Andreia Bento da Silva; Ana Teresa Serra; Pedro Mena; Pilar Legua; Maria Rosario Bronze. "Phytochemical Profile of Opuntia ficus-indica (L.) Mill Fruits (cv. ‘Orito’) Stored at Different Conditions". Foods (2022): https://www.mdpi.com/2304-8158/11/2/160. 10.3390/foods11020160 Augusti, Paula R.; Conterato, Greicy M.M.; Denardin, Cristiane C.; Prazeres, Inês D.; Serra, Ana Teresa; Bronze, Maria R.; Emanuelli, Tatiana. "Bioactivity, bioavailability, and gut microbiota transformations of dietary phenolic compounds: implications for COVID-19". The Journal of Nutritional Biochemistry 97 (2021): 108787. http://dx.doi.org/10.1016/j.jnutbio.2021.108787. Published • 10.1016/j.jnutbio.2021.108787 Boris Popovic; Bojana Blagojevic; Alicja Z. Kucharska; Dejan Agic; Nenad Magazin; Maja Milovic; Ana Teresa Serra. "Exploring fruits from genus Prunus as a source of potential pharmaceutical agents - In vitro and in silico study.". Food Chemistry 358 (2021): 129812. http://dx.doi.org/10.1016/j.foodchem.2021.129812. 10.1016/j.foodchem.2021.129812 Valério, Rita; Serra, Ana Teresa; Baixinho, João; Cardeira, Martim; Fernández, Naiara; Bronze, Maria Rosário; Duarte, Luís C.; et al. "Combined hydrothermal pre-treatment and enzymatic hydrolysis of corn fibre: Production of ferulic acid extracts and assessment of their antioxidant and antiproliferative properties". Industrial Crops and Products 170 (2021): 113731. http://dx.doi.org/10.1016/j.indcrop.2021.113731. Published • 10.1016/j.indcrop.2021.113731 Mário Bordalo; Inês J. Seabra; Andreia Bento Silva; Ana Paula Terrasso; Catarina Brito; Margarida Serra; Maria R. Bronze; et al. "Using High-Pressure Technology to Develop Antioxidant-Rich Extracts from Bravo de Esmolfe Apple Residues". Antioxidants (2021): https://www.mdpi.com/2076-3921/10/9/1469. 10.3390/antiox10091469 Oliveira-Alves, Sheila Cristina; Fabio Andrade; Prazeres, Inês; Silva, Andreia Bento; Capelo, Jorge; Bernardo Duarte; Isabel Caçador; et al. "Impact of Drying Processes on the Nutritional Composition, Volatile Profile, Phytochemical Content and Bioactivity of Salicornia ramosissima J. Woods". Antioxidants 10 8 (2021): https://www.mdpi.com/2076-3921/10/8/1312. Published • https://doi.org/10.3390/antiox10081312 Sheila C. Oliveira-Alves; Fábio Andrade; Inês Prazeres; Andreia Bento da Silva; Capelo, J.; Bernardo Duarte; Isabel Caçador; et al. "Impact of Drying Processes on the Nutritional Composition, Volatile Profile, Phytochemical Content and Bioactivity of Salicornia ramosissima J. Woods". Antioxidants (2021): https://www.mdpi.com/2076-3921/10/8/1312. 10.3390/antiox10081312 Paula Rossini Augusti; Andréia Quatrin; Renius Mello; Vivian Caetano Bochi; Eliseu Rodrigues; Inês Duarte Prazeres; Ana Catarina Macedo; et al. "Antiproliferative Effect of Colonic Fermented Phenolic Compounds from Jaboticaba (Myrciaria trunciflora) Fruit Peel in a 3D Cell Model of Colorectal Cancer". Molecules (2021): https://www.mdpi.com/1420-3049/26/15/4469. 10.3390/molecules26154469 Ana Teresa Serra; Sandra D. Silva; Luis Gouveia; Agostinho Alexandre; Carolina V. Pereira; Ana Barbara Pereira; Ana Carvalho Partidário; et al. "A Single Dose of Marine Chlorella vulgaris Increases Plasma Concentrations of Lutein, ß-Carotene and Zeaxanthin in Healthy Male Volunteers". Antioxidants (2021): https://www.mdpi.com/2076-3921/10/8/1164. 10.3390/antiox10081164 Folgado, André; Serra, Ana Teresa; Prazeres, Inês; Bento-Silva, Andreia; Bronze, M. Rosário; Abranches, Rita. "Hairy root cultures of Cynara cardunculus L. as a valuable source of hydroxycinnamic acid compounds". Plant Cell, Tissue and Organ Culture (PCTOC) 147 1 (2021): 37-47. http://dx.doi.org/10.1007/s11240-021-02102-6. 10.1007/s11240-021-02102-6 Ana Henriques Mota; Inês Prazeres; Henrique Mestre; Andreia Bento da Silva; Maria João Rodrigues; Duarte, N; Ana Teresa Serra; et al. "A Newfangled Collagenase Inhibitor Topical Formulation Based on Ethosomes with Sambucus nigra L. Extract". Pharmaceuticals (2021): https://www.mdpi.com/1424-8247/14/5/467. 10.3390/ph14050467 Andreia Bento da Silva; Duarte, N; Elsa Mecha; Maria Belo; Ana Teresa Serra; Maria Carlota Vaz Patto; Maria Rosário Bronze. "Broa, an Ethnic Maize Bread, as a Source of Phenolic Compounds". Antioxidants (2021): https://www.mdpi.com/2076-3921/10/5/672. 10.3390/antiox10050672 Ayouaz, Siham; Oliveira-Alves, Sheila Cristina; Serra, Ana Teresa; LEFSIH, Khalef; Samah, Madani; Bento da Silva, Andreia; Madani, Khodir; Bronze, Maria Rosário. "LC-DAD-ESI-MS/MS analysis, cytotoxic and antiproliferative effect of chlorogenic acid derivates rich extract from Nerium oleander L. pink flowers". Food & Function (2021): http://dx.doi.org/10.1039/d0fo02640a. Accepted • 10.1039/d0fo02640a Blagojevic, Bojana; Agic, Dejan; Serra, Ana Teresa; Matic, Sara; Matovina, Mihaela; Bijelic, Sandra; Popovic, Boris M.. "An in vitro and in silico evaluation of bioactive potential of cornelian cherry (Cornus mas L.) extracts rich in polyphenols and iridoids". Food Chemistry 335 (2021): 127619. http://dx.doi.org/10.1016/j.foodchem.2020.127619. Published • 10.1016/j.foodchem.2020.127619 Brito, Cheila; Tomás, Ana; Silva, Sandra; Bronze, Maria Rosário; Serra, Ana Teresa; Pojo, Marta. "The Impact of Olive Oil Compounds on the Metabolic Reprogramming of Cutaneous Melanoma Cell Models". Molecules 26 2 (2021): 289. http://dx.doi.org/10.3390/molecules26020289. Open access • Published • 10.3390/molecules26020289 Mota, Ana Henriques; Duarte, Noélia; Serra, Ana Teresa; Ferreira, António; Bronze, Maria Rosário; Custódio, Luísa; Gaspar, Maria Manuela; et al. "Further Evidence of Possible Therapeutic Uses of Sambucus nigra L. Extracts by the Assessment of the In Vitro and In Vivo Anti-Inflammatory Properties of Its PLGA and PCL-Based Nanoformulations". Pharmaceutics 12 12 (2020): 1181. http://dx.doi.org/10.3390/pharmaceutics12121181. Open access • Published • 10.3390/pharmaceutics12121181 Serra, Diana; Henriques, Joana F.; Serra, Teresa; Bento Silva, Andreia; Bronze, Maria Rosário; Dinis, Teresa C. P.; Almeida, Leonor M.. "An Anthocyanin-Rich Extract Obtained from Portuguese Blueberries Maintains Its Efficacy in Reducing Microglia-Driven Neuroinflammation after Simulated Digestion". Nutrients 12 12 (2020): 3670. http://dx.doi.org/10.3390/nu12123670. Published • 10.3390/nu12123670 Siham Ayouaz; Sheila Cristina Oliveira-Alves; Khalef Lefsih; Ana Teresa Serra; Andreia Silva; M. Samah; Jakub Karczewski; Khodir Madani; Maria Rosário Bronze. "Phenolic compounds from Nerium oleander leaves: microwave assisted extraction, characterization, antiproliferative and cytotoxic activities". Food & Function 11 7 (2020): 6319-6331. http://dx.doi.org/10.1039/d0fo01180k. 10.1039/d0fo01180k Oliveira-Alves, S.C.; Pereira, R.S.; Pereira, A.B.; Ferreira, A.; Mecha, E.; Silva, A.B.; Serra, A.T.; Bronze, M.R.. "Identification of functional compounds in baru (Dipteryx alata Vog.) nuts: Nutritional value, volatile and phenolic composition, antioxidant activity and antiproliferative effect". Food Research International 131 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85078983393&partnerID=MN8TOARS. 10.1016/j.foodres.2020.109026 Alexandre, A.M.R.C.; Serra, A.T.; Matias, A.A.; Duarte, C.M.M.; Bronze, M.R.. "Supercritical fluid extraction of Arbutus unedo distillate residues - Impact of process conditions on antiproliferative response of extracts". Journal of CO2 Utilization 37 (2020): 29-38. http://www.scopus.com/inward/record.url?eid=2-s2.0-85076199823&partnerID=MN8TOARS. 10.1016/j.jcou.2019.11.002 Sousa, D.P.; Pojo, M.; Pinto, A.T.; Leite, V.; Serra, A.T.; Cavaco, B.M.. "Nobiletin Alone or in Combination with Cisplatin Decreases the Viability of Anaplastic Thyroid Cancer Cell Lines". Nutrition and Cancer 72 2 (2020): 352-363. http://www.scopus.com/inward/record.url?eid=2-s2.0-85068744051&partnerID=MN8TOARS. 10.1080/01635581.2019.1634745 Cordeiro, T.; Paninho, A.B.; Bernardo, M.; Matos, I.; Pereira, C.V.; Serra, A.T.; Matias, A.; Ventura, M.G.. "Biocompatible locust bean gum as mesoporous carriers for naproxen delivery". Materials Chemistry and Physics 239 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85070366997&partnerID=MN8TOARS. 10.1016/j.matchemphys.2019.121973 Popovic, B.M.; Blagojevic, B.; Ždero Pavlovic, R.; Micic, N.; Bijelic, S.; Bogdanovic, B.; Mišan, A.; Duarte, C.M.M.; Serra, A.T.. "Comparison between polyphenol profile and bioactive response in blackthorn (Prunus spinosa L.) genotypes from north Serbia-from raw data to PCA analysis". Food Chemistry 302 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85070914325&partnerID=MN8TOARS. 10.1016/j.foodchem.2019.125373 Pereira, C.V.; Duarte, M.; Silva, P.; da Silva, A.B.; Duarte, C.M.M.; Cifuentes, A.; García-Cañas, V.; et al. "Polymethoxylated flavones target cancer stemness and improve the antiproliferative effect of 5-fluorouracil in a 3D cell model of colorectal cancer". Nutrients 11 2 (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85061145281&partnerID=MN8TOARS. 10.3390/nu11020326 Direito, R.; Rocha, J.; Serra, A.-T.; Fernandes, A.; Freitas, M.; Fernandes, E.; Pinto, R.; et al. "Anti-inflammatory Effects of Persimmon (Diospyros kaki L.) in Experimental Rodent Rheumatoid Arthritis". Journal of Dietary Supplements (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85070255174&partnerID=MN8TOARS. 10.1080/19390211.2019.1645256 Serra, A.T.; Serra, M.; Silva, A.C.; Brckalo, T.; Seshire, A.; Brito, C.; Wolf, M.; Alves, P.M.. "Scalable culture strategies for the expansion of patient-derived cancer stem cell lines". Stem Cells International 2019 (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85065849024&partnerID=MN8TOARS. 10.1155/2019/8347595 Mecha, E.; Leitão, S.T.; Carbas, B.; Serra, A.T.; Moreira, P.M.; Veloso, M.M.; Gomes, R.; et al. "Characterization of soaking process' impact in common beans phenolic composition: Contribute from the unexplored Portuguese germplasm". Foods 8 8 (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85070924922&partnerID=MN8TOARS. 10.3390/foods8080296 Silva, H.D.; Beldíková, E.; Poejo, J.; Abrunhosa, L.; Serra, A.T.; Duarte, C.M.M.; Brányik, T.; et al. "Evaluating the effect of chitosan layer on bioaccessibility and cellular uptake of curcumin nanoemulsions". Journal of Food Engineering 243 (2019): 89-100. http://www.scopus.com/inward/record.url?eid=2-s2.0-85053531036&partnerID=MN8TOARS. 10.1016/j.jfoodeng.2018.09.007 Silva, I.; Estrada, M.F.; V. Pereira, C.; da Silva, A.B.; Bronze, M.R.; Alves, P.M.; Duarte, C.M.M.; Brito, C.; Serra, A.T.. "Polymethoxylated Flavones from Orange Peels Inhibit Cell Proliferation in a 3D Cell Model of Human Colorectal Cancer". Nutrition and Cancer 70 2 (2018): 257-266. http://www.scopus.com/inward/record.url?eid=2-s2.0-85041012964&partnerID=MN8TOARS. 10.1080/01635581.2018.1412473 Kheyar-Kraouche, N.; da Silva, A.B.; Serra, A.T.; Bedjou, F.; Bronze, M.R.. "Characterization by liquid chromatography–mass spectrometry and antioxidant activity of an ethanolic extract of Inula viscosa leaves". Journal of Pharmaceutical and Biomedical Analysis 156 (2018): 297-306. http://www.scopus.com/inward/record.url?eid=2-s2.0-85046636525&partnerID=MN8TOARS. 10.1016/j.jpba.2018.04.047 Silva, H.D.; Poejo, J.; Pinheiro, A.C.; Donsì, F.; Serra, A.T.; Duarte, C.M.M.; Ferrari, G.; Cerqueira, M.A.; Vicente, A.A.. "Evaluating the behaviour of curcumin nanoemulsions and multilayer nanoemulsions during dynamic in vitro digestion". Journal of Functional Foods 48 (2018): 605-613. http://www.scopus.com/inward/record.url?eid=2-s2.0-85051145744&partnerID=MN8TOARS. 10.1016/j.jff.2018.08.002 Saldanha Do Carmo, C.; Maia, C.; Poejo, J.; Lychko, I.; Gamito, P.; Nogueira, I.; Bronze, M.R.; Serra, A.T.; Duarte, C.M.M.. "Microencapsulation of a-tocopherol with zein and ß-cyclodextrin using spray drying for colour stability and shelf-life improvement of fruit beverages". RSC Advances 7 51 (2017): 32065-32075. http://www.scopus.com/inward/record.url?eid=2-s2.0-85021750173&partnerID=MN8TOARS. 10.1039/c6ra25946d Pereira, L.P.; Silva, P.; Duarte, M.; Rodrigues, L.; Duarte, C.M.M.; Albuquerque, C.; Serra, A.T.. "Targeting colorectal cancer proliferation, stemness and metastatic potential using Brassicaceae extracts enriched in isothiocyanates: A 3D cell model-based study". Nutrients 9 4 (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85018480043&partnerID=MN8TOARS. 10.3390/nu9040368 Rodrigues, L.; Silva, I.; Poejo, J.; Serra, A.T.; Matias, A.A.; Simplício, A.L.; Bronze, M.R.; Duarte, C.M.M.. "Recovery of antioxidant and antiproliferative compounds from watercress using pressurized fluid extraction". RSC Advances 6 37 (2016): 30905-30918. http://www.scopus.com/inward/record.url?eid=2-s2.0-84962027601&partnerID=MN8TOARS. 10.1039/c5ra28068k Mata, A.; Ferreira, J.P.; Semedo, C.; Serra, T.; Duarte, C.M.M.; Bronze, M.R.. "Contribution to the characterization of Opuntia spp. juices by LC-DAD-ESI-MS/MS". Food Chemistry 210 (2016): 558-565. http://www.scopus.com/inward/record.url?eid=2-s2.0-84965161448&partnerID=MN8TOARS. 10.1016/j.foodchem.2016.04.033 Matias, A.A.; Rosado-Ramos, R.; Nunes, S.L.; Figueira, I.; Serra, A.T.; Bronze, M.R.; Santos, C.N.; Duarte, C.M.M.. "Protective Effect of a (Poly)phenol-Rich Extract Derived from Sweet Cherries Culls against Oxidative Cell Damage". Molecules 21 4 (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-84968866143&partnerID=MN8TOARS. 10.3390/molecules21040406 Figueira, M.-E.; Oliveira, M.; Direito, R.; Rocha, J.; Alves, P.; Serra, A.-T.; Duarte, C.; et al. "Protective effects of a blueberry extract in acute inflammation and collagen-induced arthritis in the rat". Biomedicine and Pharmacotherapy 83 (2016): 1191-1202. http://www.scopus.com/inward/record.url?eid=2-s2.0-84989266756&partnerID=MN8TOARS. 10.1016/j.biopha.2016.08.040 Gonçalves, V.S.S.; Matias, A.A.; Poejo, J.; Serra, A.T.; Duarte, C.M.M.. "Application of RPMI 2650 as a cell model to evaluate solid formulations for intranasal delivery of drugs". International Journal of Pharmaceutics 515 1-2 (2016): 1-10. http://www.scopus.com/inward/record.url?eid=2-s2.0-84991778563&partnerID=MN8TOARS. 10.1016/j.ijpharm.2016.09.086 Santo, V.E.; Estrada, M.F.; Rebelo, S.P.; Abreu, S.; Silva, I.; Pinto, C.; Veloso, S.C.; et al. "Adaptable stirred-tank culture strategies for large scale production of multicellular spheroid-based tumor cell models". Journal of Biotechnology 221 (2016): 118-129. http://www.scopus.com/inward/record.url?eid=2-s2.0-84957944330&partnerID=MN8TOARS. 10.1016/j.jbiotec.2016.01.031 Serra, Ana. "Brassicas como fonte de compostos anticancerígenos: matéria-prima para o desenvolvimento de Nutracêuticos ricos em isotiocianatos". Boletim de Biotecnologia 2 6 (2015): 13-15. Open access • Published Rocha, J.; Eduardo-Figueira, M.; Barateiro, A.; Fernandes, A.; Brites, D.; Bronze, R.; Duarte, C.M.; et al. "Anti-inflammatory effect of rosmarinic acid and an extract of rosmarinus officinalis in rat models of local and systemic inflammation". Basic and Clinical Pharmacology and Toxicology 116 5 (2015): 398-413. http://www.scopus.com/inward/record.url?eid=2-s2.0-84926358222&partnerID=MN8TOARS. 10.1111/bcpt.12335 Saldanha Do Carmo, C.; Nunes, A.N.; Serra, A.T.; Ferreira-Dias, S.; Nogueira, I.; Duarte, C.M.M.. "A way to prepare a liposoluble natural pink colourant". Green Chemistry 17 3 (2015): 1510-1518. http://www.scopus.com/inward/record.url?eid=2-s2.0-84924363156&partnerID=MN8TOARS. 10.1039/c4gc01801j Figueira, M.E.; Câmara, M.B.; Direito, R.; Rocha, J.; Serra, A.T.; Duarte, C.M.M.; Fernandes, A.; et al. "Chemical characterization of a red raspberry fruit extract and evaluation of its pharmacological effects in experimental models of acute inflammation and collagen-induced arthritis". Food and Function 5 12 (2014): 3241-3251. http://www.scopus.com/inward/record.url?eid=2-s2.0-84912123071&partnerID=MN8TOARS. 10.1039/c4fo00376d Matias, A.; Nunes, S.L.; Poejo, J.; Mecha, E.; Serra, A.T.; Madeira, P.J.A.; Bronze, M.R.; Duarte, C.M.M.. "Antioxidant and anti-inflammatory activity of a flavonoid-rich concentrate recovered from Opuntia ficus-indica juice". Food and Function 5 12 (2014): 3269-3280. http://www.scopus.com/inward/record.url?eid=2-s2.0-84912076778&partnerID=MN8TOARS. 10.1039/c4fo00071d Genebra, T.; Santos, R.R.; Francisco, R.; Pinto-Marijuan, M.; Brossa, R.; Serra, A.T.; Duarte, C.M.M.; Chaves, M.M.; Zarrouk, O.. "Proanthocyanidin accumulation and biosynthesis are modulated by the irrigation regime in tempranillo seeds". International Journal of Molecular Sciences 15 7 (2014): 11862-11877. http://www.scopus.com/inward/record.url?eid=2-s2.0-84903887458&partnerID=MN8TOARS. 10.3390/ijms150711862 Varona, S.; Rodríguez Rojo, S.; Martín, Á.; Cocero, M.J.; Serra, A.T.; Crespo, T.; Duarte, C.M.M.. "Antimicrobial activity of lavandin essential oil formulations against three pathogenic food-borne bacteria". Industrial Crops and Products 42 1 (2013): 243-250. http://www.scopus.com/inward/record.url?eid=2-s2.0-84862741600&partnerID=MN8TOARS. 10.1016/j.indcrop.2012.05.020 Serra, A.T.; Poejo, J.; Matias, A.A.; Bronze, M.R.; Duarte, C.M.M.. "Evaluation of Opuntia spp. derived products as antiproliferative agents in human colon cancer cell line (HT29)". Food Research International 54 1 (2013): 892-901. http://www.scopus.com/inward/record.url?eid=2-s2.0-84884554141&partnerID=MN8TOARS. 10.1016/j.foodres.2013.08.043 Almeida, A.P.; Rodríguez-Rojo, S.; Serra, A.T.; Vila-Real, H.; Simplicio, A.L.; Delgadilho, I.; Beirão Da Costa, S.; et al. "Microencapsulation of oregano essential oil in starch-based materials using supercritical fluid technology". Innovative Food Science and Emerging Technologies 20 (2013): 140-145. http://www.scopus.com/inward/record.url?eid=2-s2.0-84889096507&partnerID=MN8TOARS. 10.1016/j.ifset.2013.07.009 Serra, A.T.; Rocha, J.; Sepodes, B.; Matias, A.A.; Feliciano, R.P.; De Carvalho, A.; Bronze, M.R.; Duarte, C.M.M.; Figueira, M.E.. "Evaluation of cardiovascular protective effect of different apple varieties - Correlation of response with composition". Food Chemistry 135 4 (2012): 2378-2386. http://www.scopus.com/inward/record.url?eid=2-s2.0-84865346819&partnerID=MN8TOARS. 10.1016/j.foodchem.2012.07.067 Tavares, L.; Fortalezas, S.; Tyagi, M.; Barata, D.; Serra, A.T.; Martins Duarte, C.M.; Duarte, R.O.; et al. "Bioactive compounds from endemic plants of Southwest Portugal: Inhibition of acetylcholinesterase and radical scavenging activities". Pharmaceutical Biology 50 2 (2012): 239-246. http://www.scopus.com/inward/record.url?eid=2-s2.0-84855793220&partnerID=MN8TOARS. 10.3109/13880209.2011.596209 Da Costa, S.B.; Duarte, C.; Bourbon, A.I.; Pinheiro, A.C.; Serra, A.T.; Martins, M.M.; Januário, M.I.N.; et al. "Effect of the matrix system in the delivery and in vitro bioactivity of microencapsulated Oregano essential oil". Journal of Food Engineering 110 2 (2012): 190-199. http://www.scopus.com/inward/record.url?eid=2-s2.0-84865764214&partnerID=MN8TOARS. 10.1016/j.jfoodeng.2011.05.043 Serra, A.T.; Duarte, R.O.; Bronze, M.R.; Duarte, C.M.M.. "Identification of bioactive response in traditional cherries from Portugal". Food Chemistry 125 2 (2011): 318-325. http://www.scopus.com/inward/record.url?eid=2-s2.0-78049429424&partnerID=MN8TOARS. 10.1016/j.foodchem.2010.07.088 Serra, A.T.; Matias, A.A.; Almeida, A.P.C.; Bronze, M.R.; Alves, P.M.; De Sousa, H.C.; Duarte, C.M.M.. "Processing cherries (Prunus avium) using supercritical fluid technology. Part 2. Evaluation of SCF extracts as promising natural chemotherapeutical agents". Journal of Supercritical Fluids 55 3 (2011): 1007-1013. http://www.scopus.com/inward/record.url?eid=2-s2.0-78650238209&partnerID=MN8TOARS. 10.1016/j.supflu.2010.06.006 Feliciano, R.P.; Antunes, C.; Ramos, A.; Serra, A.T.; Figueira, M.E.; Duarte, C.M.M.; Carvalho, A.d.; Bronze, M.R.. "Characterization of traditional and exotic apple varieties from Portugal. Part 1 - Nutritional, phytochemical and sensory evaluation". Journal of Functional Foods 2 1 (2010): 35-45. http://www.scopus.com/inward/record.url?eid=2-s2.0-77649184672&partnerID=MN8TOARS. 10.1016/j.jff.2009.12.004 Serra, A.T.; Matias, A.A.; Frade, R.F.M.; Duarte, R.O.; Feliciano, R.P.; Bronze, M.R.; Figueira, M.E.; de Carvalho, A.; Duarte, C.M.M.. "Characterization of traditional and exotic apple varieties from Portugal. Part 2 - Antioxidant and antiproliferative activities". Journal of Functional Foods 2 1 (2010): 46-53. http://www.scopus.com/inward/record.url?eid=2-s2.0-77649179441&partnerID=MN8TOARS. 10.1016/j.jff.2009.12.005 Matias, A.A.; Serra, A.T.; Silva, A.C.; Perdigão, R.; Ferreira, T.B.; Marcelino, I.; Silva, S.; et al. "Portuguese winemaking residues as a potential source of natural anti-adenoviral agents". International Journal of Food Sciences and Nutrition 61 4 (2010): 357-368. http://www.scopus.com/inward/record.url?eid=2-s2.0-77952555256&partnerID=MN8TOARS. 10.3109/09637480903430990 Serra, A.T.; Seabra, I.J.; Braga, M.E.M.; Bronze, M.R.; De Sousa, H.C.; Duarte, C.M.M.. "Processing cherries (Prunus avium) using supercritical fluid technology. Part 1: Recovery of extract fractions rich in bioactive compounds". Journal of Supercritical Fluids 55 1 (2010): 184-191. http://www.scopus.com/inward/record.url?eid=2-s2.0-78049250298&partnerID=MN8TOARS. 10.1016/j.supflu.2010.06.005 Tavares, L.; Carrilho, D.; Tyagi, M.; Barata, D.; Serra, A.T.; Duarte, C.M.M.; Duarte, R.O.; et al. "Antioxidant capacity of macaronesian traditional medicinal plants". Molecules 15 4 (2010): 2576-2592. http://www.scopus.com/inward/record.url?eid=2-s2.0-77951873298&partnerID=MN8TOARS. 10.3390/molecules15042576 Feliciano, R.P.; Bravo, M.N.; Pires, M.M.; Serra, A.T.; Duarte, C.M.; Boas, L.V.; Bronze, M.R.. "Phenolic content and antioxidant activity of moscatel dessert wines from the setúbal region in portugal". Food Analytical Methods 2 2 (2009): 149-161. http://www.scopus.com/inward/record.url?eid=2-s2.0-62349142072&partnerID=MN8TOARS. 10.1007/s12161-008-9059-7 Serra, A.T.; Matias, A.A.; Nunes, A.V.M.; Leitão, M.C.; Brito, D.; Bronze, R.; Silva, S.; et al. "In vitro evaluation of olive- and grape-based natural extracts as potential preservatives for food". Innovative Food Science and Emerging Technologies 9 3 (2008): 311-319. http://www.scopus.com/inward/record.url?eid=2-s2.0-44149110650&partnerID=MN8TOARS. 10.1016/j.ifset.2007.07.011
Thesis / Dissertation	Serra, Ana. "Valorization of traditional Portuguese apples and cherries- Biochemical characterization and Development of Functional Ingredients". PhD, Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, 2010.

Other

Other output

Cherry and cactus pear natural extracts for colon cancer therapy- in vitro evaluation of chemopreventive and chemosensitization effects. Serra, A.T., Poejo, J., Matias, A., Bronze, M.R., Duarte, C.M.M. Cherry and cactus pear natural extracts for colon cancer therapy- in vitro evaluation of chemopreventive and chemosensitization effects. Biomed Pap Fac Univ Palacky Olomouc Repub. 2012 Jun; 156 (supplement 1)S1:S100.. 2012. Serra, Ana.
Evaluation of cactus pear (Opuntia spp.) extracts as promising bioactive ingredients for colon cancer therapy. Poejo, J., Matias, A.A., Bronze, M.R., Duarte, C.M.M., Serra, A.T. (2011). Evaluation of cactus pear (Opuntia spp.) extracts as promising bioactive ingredients for colon cancer therapy. European Journal of Pharmacology, 668, Supplement 1, e18.. 2011. Serra, Ana.
Bioactive extracts derived from fruits (Prunus avium and Opuntia ficus-indica) as potential natural anti-inflammatory modulators in inflammatory bowel diseases. Nunes, S., Serra, A.T., Bronze, M.R., Simplício, A.L., Matias, A.A., Duarte, C.M.M (2011). Bioactive extracts derived from fruits (Prunus avium and Opuntia ficus-indica) as potential natural anti-inflammatory modulators in inflammatory bowel diseases. European Journal of Pharmacology, 668, Supplement 1, e27.. 2011. Serra, Ana.
Anti-inflammatory effect of Rosmarinic acid on a model of carrageenan-induced paw edema.. Rocha, J., Sepodes, B., Figueira, M.E., Bronze,M.R., Duarte,C., Serra, T., Lima, B.S., Mota-Filipe. H. (2009). Anti-inflammatory effect of Rosmarinic acid on a model of carrageenan-induced paw edema. FASEB Journal,23, 571.2.. 2009. Serra, Ana.

Activities

Oral presentation

	Presentation title	Event name Host (Event location)
2021/02/04	Unveiling the protective role of natural bioactive compounds towards colorectal cancer	Natural Products application: health, cosmetic and food, online edition Instituto Politecnico de Bragança (Bragança, Portugal)
2020/10/18	Unveiling the protective role of food bioactive compounds in colorectal cancer	SIMPÓSIO TRANSDISCIPLINARIDADE NAS CIÊNCIAS E NAS ARTES Universidade Fereral de Santa Maria (Brazil)
2020/09/30	Evidência científica nas alegações de saúde: Testes clínicos.	Webinar: Alegações de Saúde e Alimentos Funcionais AINIA (Spain)
2018/01	Targeting colorectal cancer stemness by Brassicaceae extracts and isothiocyanates: a 3D cell model-based study combined with RNA analysis.	INTERNATIONAL CONFERENCE ON FOODOMICS - 5th EDITION Foodomics 2018 - from Data to Knowledge
2017/10	Targeting colorectal cancer stem cells by citrus polymethoxylated flavones: a 3D cell model approach	ICPH2017- 8th International Conference on Polyphenols and Health
2017/06	Potencial quimio-terapêutico de extractos naturais de brócolos e agrião-de-água enriquecidos em isotiocianatos na erradicação de células estaminais de cancro do cólon e recto	Semana Digestiva
2017/06	Efeito quimioterapêutico de compostos bioactivos derivados dos citrinos- acção sobre células estaminais de cancro colorectal	Semana Digestiva
2017/04	Recovery of bioactive ingredients from cruciferous vegetables surpluses using supercritical fluid technology	16th European Meeting on Supercritical Fluids
2017/04	Extracts from residues of Arbutus unedo distillation process obtained by SFE: antiproliferative and citotoxicity evaluation	16th European Meeting on Supercritical Fluids
2017	Taking advantage from nature for cancer therapy: Design of nutraceuticals targeting colorectal cancer stem cells	Ciclo de Seminários UIPM – IPOLFG
2016/11	Effect of a Functional Fruit Concentrate on post-prandial glycaemic response in pre-diabetes and type 2 diabetes patients: exploring the inter-individual variation	1st International Conference on Food Bioactives & Health
2016/11	Impact of Botanical origin on the nutraceutical potential of Portuguese honeys.	Food Factor Conference I
2016	Tailored applications for polyphenols: Pharma	WineSense Spring School.
2016	A Dieta Mediterrânica: do passado para um futuro mais saudável	Festival Cogito Câmara Municipal de Oeiras
2015/10	Exploring the anti-tumoral effect of citrus polyphenols using a 3D cell model of colorectal cancer	7 th International Conference on Polyphenols and Health
2015/01	DEVELOPMENT OF A NUTRACEUTICAL FOR CHEMOTHERAPEUTIC APPLICATIONS - PMF-RICH EXTRACTS DERIVED FROM CITRUS WASTES USING SUPERCRITICAL FLUID TECHNOLOGY	Citrus Waste Valorization Workshop- EuBIS Cost Action
2014/01	Recovery of natural pigments from cactus pears	COST TD1203 - EUBis Workshop
2014	Ao encontro dos Benefícios da Dieta Mediterrânica- uma abordagem pré-clinica	Sessão de Conferências e Debate - Alimentação, Saúde e Agro-Indústria,
2014	Recovery of multifunctional food and pharma ingredients from fruit and vegetable wastes	Food wastes processing in the frame of the biorefinery concept
2014	Efeitos adversos da terapêutica oncológica: Existe um papel para os alimentos funcionais como adjuvantes?	Simposium: “Foods for Health and Wellness- Prespectives in Oncology
2014	Plataforma de Bioactividade	Congresso do Agronegócio- Brokerage Tecnológico
2014	A Dieta do Passado no Futuro: Dieta Mediterrânica	II Encontro de Nutrição e Alimentação- A Alimentação Evolui e o Ser Humano?- Desafios e Soluções
2013	Extracto de figo da India rico em betalainas: um corante natural com propriedades bioactivas	Jornadas Técnicas: Os Compostos Naturais da Indústria Alimentar”- Aplicáveis a produtos de origem animal
2013	Recovery of natural pigments from cactus pears	COST TD1203 - EUBis Workshop
2013	Development of bioactive natural ingredients using High Pressure technology	COST TD1203 WG1 Pre-treatment and extraction Meeting
2012/12	Evaluation of antiproliferative effect and cell cycle arrest on HT29 cells of different plant-derived natural extracts- Correlation of response with composition	12th International Conference on Functional Foods Ingredients and Nutraceuticals in Chronic Disease: Science and Practice (Dallas, United States)
2012/10	Development of Bioactive Natural Ingredients from Sweet Cherry and Plum wastes	Plum and Cherry Symposium- Fruit Atraction
2012	Avaliação de alegações nutricionais e de saúde sobre os alimentos- o caso do artigo 13.1	Ciclo de Conferências- Alimentos e Bebidas Funcionais- Desafios e Oportunidades para a Indústria Agroalimentar.
2012	Extracto de cereja obtido por tecnologia supercritica- um agente quimioterapêutico natural para o cancro do cólon	XI Congresso de Nutrição e Alimentação
2011/09	Polyphenols-rich extracts obtained from two Portuguese fruits (Prunus avium and Opuntia ficus-indica) as potential natural anti-inflammatory modulators in Inflammatory Bowel Diseases.	International PSE Symposium on “Phytochemicals in nutrition and health (Bari, Italy)
2011	Entrapped functional products as natural preservatives	. 1st Iberian Meeting on Natural Bioactives Entrapment for the Food Industry- Challenges and Perspectives, from nanotechnology to bioavailability
2011	Bioactivity evaluation for functionality characterisation	1st Iberian Meeting on Natural Bioactives Entrapment for the Food Industry- Challenges and Perspectives, from nanotechnology to bioavailability
2011	Ingredientes Funcionais: extracção, caracterização e formulação	VII Colóquio de Farmácia da ESTSP
2008/05	Processing cherry waste with supercritical fluids to develop a new promising nutraceutical.	11th European Meeting on Supercritical Fluids.
2008/05	Natural grape extract precipates type 1 diabetes in NOD mice	1º Encontro Nacional de Bromatologia, Hidrologia e Toxicologia
2008	In vitro evaluation of olive- and grape-based natural extracts as potential preservatives for food	Innovations in Naturals 2008- Natural Preservatives
2007/04	Preparation of lipid based delivery systems using supercritical fluid technology	Pre-satellite meeting of the 3rd Pharmaceutical Sciences World Congress
2006/10	Development of nutraceuticals from grapes and cherries wastes. 3rd International Conference of Applications in Nutrition and Health	1st International Symposium on Antioxidants and Polyphenols: Valorization from Fruits and Vegetable Wastes
2006/06	Desenvolvimento de Nutracêuticos a partir de extractos naturais de cereja e uva	1º Encontro Nacional de Bromatologia, Hidrologia e Toxicologia

Supervision

	Thesis Title Role	Degree Subject (Type) Institution / Organization
2020/03 - Current	Bioactivity evaluation of natural extracts and nanoparticles Supervisor	Iniciação à Investigação Cientifica (Scientific initiation) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2019/10 - Current	3D cell culture; antiproliferative assays of natural extracts in human cell models Supervisor
2018/06 - Current	3D cell culture; antiproliferative evaluation using cell models Supervisor
2018/02/01 - Current	Targeting colorectal cancer cell proliferation by bioactive triterpenic compounds derived from olive tree and raspberries using a 3D cell model approach Supervisor	Universidade de Lisboa Instituto Superior Técnico, Portugal
2022/03/01 - 2023/04/30	Anticancer effects of compounds derived from Cannabis plant - in vitro studies Supervisor of Martim Cardeira	Curso de Pos-graduação de Investigação Científica (Other) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2022/02/01 - 2023/04/30	Unveiling the anticancer potential of hydroxytyrosol in LoVo cell spheroids Supervisor of Maria Margarida Pereira Leite	Master in Biomedical Engineering (Master) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2021/11/01 - 2023/04/30	Azeite, compostos fenólicos e alegação de saúde: os azeites nacionais Supervisor	Mestrado em Qualidade Alimentar e Saúde (Master) Universidade de Lisboa Faculdade de Farmácia, Portugal
2020/09/01 - 2022/03/31	In vitro bioacessibility and bioactivity of phenolic compounds from halophyte plants Supervisor	Master in Biotechnology (Master) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2021/03/01 - 2022/02/28	Evaluation of the anticancer properties of hydroxytyrosol Supervisor	Iniciação à Investigação Científica (Scientific initiation) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2020/12/01 - 2021/11	Phytochemical characterization of different rice varieties Supervisor	Iniciação à Investigação Científica (Scientific initiation) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2020/08/01 - 2021/07/31	Phytochemical characterization and bioactivity evaluation of saffrom extracts Supervisor	Iniciação à Investigação científica (Scientific initiation) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2021/02/15 - 2021/03/15	Phytochemical and antioxidant characterization of endemic plants from spain Supervisor	Universidad Miguel Hernández de Elche, Spain
2019/06 - 2019/12	Culture of human cells in 2D and 3D approaches; antiproliferative and cytotoxicity assays of natural extracts Supervisor
2016/09/01 - 2017/11/30	Exploring the potential of natural extracts obtained from winemaking waste streams for cosmetic applications Co-supervisor	Bioquímica para a Saúde Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2015/09/01 - 2016/11/30	Effect of citrus bioactive compounds on targeting human colorectal cancer stem cells Supervisor	Biotecnologia (Master) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2015/09/01 - 2016/11/30	Exploring the chemotherapeutic potential of Brassicaceae extracts in colorectal cancer cell spheroids Supervisor	Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2015/09/01 - 2016/11/01	Exploring the Anti-diabetic Effect of White Wine Supervisor	Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2016/04 - 2016/09	Antiproliferative effect of fruits using cell-based assays Supervisor
2013/09/01 - 2014/11/30	Supercritical fluid extraction or aromatic plants: phytochemical characterization and antiproliferative effect Co-supervisor	Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2012/10/01 - 2013/12/30	AVALIAÇÃO DA CAPACIDADE ANTIOXIDANTE DE EXTRACTOS NATURAIS DE MAÇÃ E AZEITONA USANDO MODELOS CELULARES EM MONOCAMADA (2D) E AGREGADOS (3D) Supervisor	Universidade Lusófona de Humanidades e Tecnologias, Portugal
2012/09/01 - 2013/12/29	Bioprocess engineering of iPSC-derived cardiomyocytes for cardiovascular research Co-supervisor	Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2012/09/01 - 2013/09/30	Evaluation of Chemotherapeutic Potential of Natural Extracts Using 3D Models of Colon Cancer Supervisor	Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2010/09/01 - 2011/09/30	Evaluation of Opuntia spp. Bioactive products as promising natural chemotherapeutical agents- an in vitro approach Supervisor	Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Event organisation

	Event name Type of event (Role)	Institution / Organization
2019/07 - Current	Member of the Organizing and Scientific Committees of the ITQB Open Day 2019- Technology Division (2019/10) Exhibition (Member of the Organising Committee)	Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2017/09 - Current	Member of the Organizing Committee of “2nd Conference on Food Bioactives and Health” (2018/10) Conference (Member of the Organising Committee)
2014/01 - Current	Member of the Organizing Committee of iBET-25 years Celebration Day. (2014/06) Meeting (Member of the Organising Committee)	Instituto de Biologia Experimental e Tecnológica, Portugal
2012/01/01 - Current	Member of the Organizing Committee of Ciclo de Conferências: Alimentos e Bebidas Funcionais- Desafios e Oportunidades para a Indústria Agro Alimentar. 1ª Sessão: Defesa de Alegações de Saúde na Indústria Alimentar e Bebidas. (2012/06) Conference (Member of the Organising Committee)	Instituto de Biologia Experimental e Tecnológica, Portugal
2015/06/22 - 2015/06/26	Member of the Organizing Committee of Winesense -1st Trainning School: In vitro assays for natural ingredients development (2015/06/22 - 2015/06/26) Other (Member of the Organising Committee)	Instituto de Biologia Experimental e Tecnológica, Portugal

Jury of academic degree

	Topic Role	Candidate name (Type of degree) Institution / Organization
2023/02/01	BIODISPONIBILIDADE E DISTRIBUIÇÃO TECIDUAL DE COMPOSTOS FENÓLICOS DE UM EXTRATO DE MIRTILO BIOCOMPATÍVEL OBTIDO COM SOLVENTE EUTÉTICO PROFUNDO NATURAL (Thesis) Arguer	Dariane Trivisiol da Silva (PhD) Universidade Federal de Santa Maria, Brazil
2022/11/29	EXTRATOS DE CEREJEIRA-DO-RIO-GRANDE (Eugenia involucrata): AVALIAÇÃO DA BIOATIVIDADE EM MODELOS IN VITRO (Thesis) Arguer	Franciele Aline Smaniotto (Master) Universidade Federal de Santa Maria, Brazil
2022/11/25	Avaliação funcional de misturas de frutas e hortícolas e potencial impacto na Saúde Pública (Thesis) Main arguer	Suzylena Pereira Fernandes Levy (Master) Universidade de Lisboa Faculdade de Farmácia, Portugal
2022/10	Suplementos Alimentares na Ansiedade e Depressão (Thesis) Main arguer	Ana Isabel Fernandes Jesus Marques (Master) Universidade de Lisboa Faculdade de Farmácia, Portugal
2022/05	Suplementos alimentares no combate à osteoporose na terceira idade (Thesis) Main arguer	Gilberto Doirado Nunes (Master) Universidade de Lisboa Faculdade de Farmácia, Portugal
2022/05	Suplementos alimentares na Diabetes mellitus tipo 2: Prevenção e interação com a medicação (Thesis) Main arguer	Guilherme Gomes Martins (Master) Universidade de Lisboa Faculdade de Farmácia, Portugal
2021/02/24	Development of substrates for reconstructed human dermis based on polyhydroxyalkanoates (PHAs) and FucoPol (Thesis) Main arguer	Ana Margarida Correia Rafael (Master) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2021/02/01	STUDY OF HALOPHYTE PLANTS PRODUCED IN PORTUGAL (Thesis) Main arguer	Fábio Alexandre Sousa Andrade (Master) Universidade de Lisboa Faculdade de Farmácia, Portugal
2020/01/12	Antioxidant and antimicrobial activity of supercritical fluid extracts from natural matrices (Thesis) Main arguer	Tiago Rodrigues (Master) Universidade de Lisboa Faculdade de Farmácia, Portugal
2019/07/09	Persimmons: phytochemical characterization and impact on health (antioxidant activity, antiproliferative and anti-inflammatory effect) (Thesis) Arguer	Rosa Direito (PhD) Universidade de Lisboa Faculdade de Farmácia, Portugal
2017/12/04	Food science and Technology (Thesis) Main arguer	Catarina Nunes Cardoso (Master) Universidade de Lisboa Faculdade de Farmácia, Portugal
2017/11/25	Chemical characterization of beans and health impact- lowering glycaemic index (Thesis) Main arguer	Verónica Silva Correia (Master) Universidade de Lisboa Faculdade de Farmácia, Portugal
2016/02/07	Raspberries: phytochemical characterization, impact on health, health claims (Thesis) Arguer	Madalena Bettencourt (PhD) Universidade de Lisboa Faculdade de Farmácia, Portugal
2015/11/15	Biomarkers of colorectal cancer (Thesis) Main arguer	Marlene Duarte (Master) Instituto Superior de Ciências da Saúde Egas Moniz, Portugal
2012/11/01	Characterization of Opuntia samples (Thesis) Main arguer	Catarina Semedo (Master) Universidade de Lisboa Faculdade de Farmácia, Portugal

Association member

	Society Organization name	Role
2014 - Current	Member of the European Society of Animal Cell Technology (ESACT)
2012 - Current	Member of Phytochemical Society of Europe

Conference scientific committee

	Conference name	Conference host
2018/10 - Current	2nd Conference on Food Bioactives and Health	Lisbon

Course / Discipline taught

	Academic session	Degree Subject (Type)	Institution / Organization
2021/02/26 - 2021/02/26	Science4Food- Frontiers in Biotechnology Unit	MolBios PhD program (Curso de doutoramento (conclusão de unidades curriculares))	Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2019/09/01 - 2020/06/30	Food and Health	Bioquímica para a Saúde (Mestrado)	Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2019/09/01 - 2020/06/30	Food and Health	Biotecnologia (Mestrado)	Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2019/09/01 - 2020/06/30	Food and Health	Bioquímica (Mestrado integrado)	Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2019/09/01 - 2020/06/30	Food and Health	Genética Molecular e Biomedicina (Mestrado integrado)	Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2010/01/01 - 2011/12/30	Food & Health	Controlo de Qualidade e Toxicologia dos Alimentos (Mestrado)	Universidade de Lisboa Faculdade de Farmácia, Portugal
2010/09/01 - 2011/06/30	Food & Health	Gestão da Qualidade e Segurança Alimentar (Pós-Graduação)	Universidade Lusófona de Humanidades e Tecnologias, Portugal
2009/09/01 - 2010/06/30	Food & Health	Ciências da Nutrição (Pós-Graduação)	Instituto Superior de Ciências da Saúde Egas Moniz, Portugal

Evaluation committee

	Activity description Role	Institution / Organization	Funding entity
2019/09/01 - 2023/08/31	Comissão de Avaliação da tese de doutoramento da aluna Beatriz Togal Martins (ITQB NOVA): "Oleocanthal, oleacein and metabolites: a strategy to understand their importance after olive oil consumption" Member	Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal

Journal scientific committee

	Journal title (ISSN)	Publisher
2020 - Current	Toxicology in Vitro (0887-2333)	Elsevier
2019 - Current	Nutrients (2072-6643)	MDPI AG
2019 - Current	Food & Function (2042-650X)	The Royal Society of Chemistry
2018 - Current	Food Research International (0963-9969)	Elsevier
2018 - Current	Nutrition and Cancer (1532-7914)	Informa UK (Taylor & Francis)
2018 - Current	Journal of Agricultural and Food Chemistry (1520-5118)	American Chemical Society
2018 - Current	Nutrition Research (0271-5317)	Elsevier
2017 - Current	BMC Biotechnology (1472-6750)	Springer (Biomed Central Ltd.)
2016 - Current	Stem Cells Translational Medicine (2157-6580)	Wiley (John Wiley & Sons)
2013 - Current	Ambit of Journal of Food Science and Technology	Delta State College of Education
2011 - Current	Journal of Functional Foods (1756-4646)	Elsevier
2011 - Current	The Journal of Supercritical Fluids (0896-8446)	Elsevier
2011 - 2020	Food Chemistry (0308-8146)	Elsevier

Distinctions

Award

2019	Best poster in basic Research Universidade Nova de Lisboa Centro de Estudos de Doenças Crónicas, Portugal
2018	“Green Project Awards”- Hoonorable Mention in the category of Research and Development; Project:” NutraBrass - Nutraceuticals from Brassicaceae: High Pressure Processing of Cruciferous food plants to recover biologically active ingredients with health pro Portuguese Environment Agency (APA), GCI and Quercus ANCN, Portugal
2017	Best Oral Presentation of Basic Research ("Chemotherapeutic potential of isothiocyanate-enriched natural extracts derived from broccoli and watercress in targeting human colorectal cancer stem cells") in Semana Digestiva 2017 Congress
2016	Best Poster award: “High pressure processing of cruciferous foods residues to recover bioactive ingredients with health promoting effects” (UBIS COST (EUBIS "The future of Food Waste: Challenges and opportunities for valorisation in Europe", Wageningen, T
2014	POSTER AWARD: HIGH PRESSURE PROCESSING OF CRUCIFEROUS FOODS RESIDUES TO RECOVER BIOACTIVE INGREDIENTS WITH HEALTH PROMOTING EFFECTS (Ana Matias, A.M.R.C. Alexandre, A. T. Serra, A. L. Simplicio, Catarina M.M. Duarte)
2013	PREMIO AVELEDA "White wine and health"- Awarded project: "White Wine-a healthy option with positive impact on type 2 diabetes
2012	Nutrition Awards 2012- 1st Honorable Mention in the category of "Research and Development”; Awarded project: "Bravo de Esmolfe – an apple with a beneficial effect in cardiovascular health”
2011	Nutrition Awards 2011- Winner in the category of “Innovation and Development of Products and Services”; Awarded project: “Cherry extract obtained from supercritical technology – a chemotherapeutical agent against colon cancer”

Title

2016	“Food and Nutrition Awards 2016”- Finalist in the category of Research and Development; Project:” OrangeCTherapy- Chemotherapeutic effect of citrus bioactive compounds - evaluation for targeting human colorectal cancer stem cells".
2014	"Nutrition Awards 2014”- Finalist in the category of Research and Development; Project: “NutraBrass: Nutraceuticals from Brassicas”.
2014	"Nutrition Awards 2014”- Finalist in the category of Research and Development; Project: ”Natural pigment derived from Opuntia spp”