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Aji Alex Moothedathu Raynold. Completed the Doktor (PhD) in Biomedical Engineering in 2017/09/20 at Indian Institute of Technology Delhi (India), Master in M.Pharm (Pharmaceutics) at Mahatma Gandhi University - Cheruvandoor Campus and Bachelor in B.Pharm at Government Medical College Thiruvananthapuram. Published 17 articles in journals. Has 1 Indian patent(s) registered and 2 US patents published. Participated in 14 event(s). Has received 10 awards and/or honors. Participates and/or participated as PhD Student Fellow in 1 grant(s), Project Scientist in 1 grant, Primary Investigator in 3 grant(s) and Researcher in 4 project(s). Works in the area(s) of Medical and Health Sciences with emphasis on Medical Biotechnology with emphasis on Biomaterials. In his curriculum Ciência Vitae the most frequent terms in the context of scientific, technological and artistic-cultural output are: Graft copolymers; Polymer Brushes; Drug Delivery; Formulations; Gene Delivery; Biomaterials; .
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Identification

Personal identification

Full name
Aji Alex Moothedathu Raynold

Citation names

  • Moothedathu Raynold, Aji Alex

Author identifiers

Ciência ID
9010-0779-7E72
ORCID iD
0000-0001-5453-4444

Email addresses

  • ajialex89@yahoo.com (Professional)

Websites

Knowledge fields

  • Medical and Health Sciences - Medical Biotechnology - Biomaterials

Languages

Language Speaking Reading Writing Listening Peer-review
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Hindi Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Malayalam (Mother tongue)
Education
Degree Classification
2011/01/03 - 2017/09/20
Concluded
 Biomedical Engineering (Doktor (PhD))
Major in Industrial Biomaterials
Indian Institute of Technology Delhi Center for Biomedical Engineering, India

All India Institute of Medical Sciences, India
"Development of cationic nanosystems based on poly (styrene-alt-maleic anhydride) for combinatorial delivery of drug and nucleic acid in cancer therapy " (THESIS/DISSERTATION)
 Biomaterials
2007/10/22 - 2009/12/31
Concluded
 M.Pharm (Pharmaceutics) (Master)
Major in Pharmaceutics
Mahatma Gandhi University - Cheruvandoor Campus, India
"Formulation & evaluation of solid lipid nanoparticles for intestinal lymphatic targeting of antiretroviral drug (lopinavir) " (THESIS/DISSERTATION)
 Postgraduate
Affiliation

Science

Category
Host institution 		Employer
2024/05/01 - Current Invited Auxiliary Researcher (Research) Universidade de Coimbra, Portugal
2022/05/01 - 2024/04/30 Postdoc (Research) EU Framework Programme for Research and Innovation Marie Sklodowska-Curie Actions, Belgium
Centre for Neuroscience and Cell Biology (Centro de Neurociências e Biologia Celular), Portugal
2020/02/10 - 2022/02/09 Postdoc (Research) Virginia Commonwealth University, United States
Virginia Commonwealth University, United States
2018/03/20 - 2020/02/07 Postdoc (Research) Commonwealth Secretariat, United Kingdom
Queen Mary University of London, United Kingdom
2015/11/18 - 2016/02/15 Visiting Researcher (Research) Bio-Nano Electronics Research Centre (BNERC) Toyo University Japan, Japan
Bio-Nano Electronics Research Centre (BNERC) Toyo University Japan, Japan
2010/03/15 - 2010/12/31 Research Assistant (Research) DRDO Institute of Nuclear Medicine and Allied Sciences, India
DRDO Institute of Nuclear Medicine and Allied Sciences, India
2009/03/31 - 2009/12/31 Visiting Researcher (Research) Sree Chitra Tirunal Institute for Medical Sciences and Technology, India
Sree Chitra Tirunal Institute for Medical Sciences and Technology, India

Positions / Appointments

Category
Host institution 		Employer
2017/09/20 - 2018/03/07 Project Scientist (IMPRINT) Indian Institute of Technology Delhi Center for Biomedical Engineering, India
Indian Institute of Technology Delhi Center for Biomedical Engineering, India
Projects

Grant

Designation Funders
2022/05/01 - 2024/04/30 Design and development of exosomes with brush type architecture as RNA delivery vectors for active targeting of blood brain barrier (BBB)
101019325
Principal investigator
Universidade de Coimbra, Portugal
 European Commission
Concluded
2020/02/11 - 2022/02/09 SIX-MONTH EFFECTIVE TREATMENT OF CORNEAL GRAFT REJECTION
R01EY027827
Post-doc
Virginia Commonwealth University Department of Pharmaceutics, United States
 National Institutes of Health
Concluded
2020/02/10 - 2022/02/09 Novel Nor-LAAM formulations for treating opioid use disorders
DA048768-01A1
Post-doc
Virginia Commonwealth University, United States
 National Institutes of Health
Concluded
2018/03/20 - 2020/02/07 Development of cationic polymer brushes for efficient gene delivery applications
INRF-2017-179
Principal investigator
Queen Mary University of London - Mile End Campus, United Kingdom
 Commonwealth Secretariat
Concluded
2015/05/08 - 2018/05/07 Development of hybrid polymeric nanosystems for combinatorial targeted delivery of siRNA and drug in breast cancer therapy
BT/PR10191/NNT//28/717/2013
PhD Student Fellow
Indian Institute of Technology Delhi, India
 Department of Biotechnology Ministry of Science and Technology
Concluded
2017/09/20 - 2018/03/07 Artificial skin (Bio-inspired bi-layer polymeric hybrid scaffold) for burn injuries and trauma care
F.NO.41-2/2015-T.S.I (PT) (ANN.I SL.24)
Scientific Initiation Fellow
Indian Institute of Technology Delhi Center for Biomedical Engineering, India
 India Ministry of Human Resource Development
Concluded

Contract

Designation Funders
2020/11/07 - 2022/02/09 Bioequivalence study of generic formulations of tobramycin/dexamethasone in rabbit model
HHSF223201810114C
Post-doc
Virginia Commonwealth University, United States
 U.S. Food and Drug Administration
Concluded
2020/02/10 - 2022/02/09 Novel LAAM buccal film compositions and methods of use thereof in treatment of opioid use disorders
DA048768-01A1
Post-doc
Virginia Commonwealth University, United States
 National Institutes of Health
Concluded
Outputs

Publications

Book chapter
  1. Qu, F.; Raynold, A. M.; Gautrot, J. E.. "Chapter 11. Recent Advances in the Design of Surface-initiated Polymer Brushes for Biomedical Applications". In Soft Matter for Biomedical Applications, 264-300. Royal Society of Chemistry, 2021.
Conference paper
  1. Moothedathu Raynold, Aji Alex. "Development and in vitro evaluation of an oral floating matrix tablet formulation of calcium di-sodium EDTA using gamma scintigraphy". Paper presented in SNMICON-2010: 42. annual conference of the Society of Nuclear Medicine (India) on molecular imaging and targeted radionuclide therapy: predicting the future; Chandigarh (India); 11-14 Nov 2010, Chandigarh, 2010.
    Published
  2. Raynold, Aji. "Scintigraphic evaluation of floating, gastroretentive formulation of clarithramycin in healthy human volunteers". Paper presented in SNMICON-2010: 42. annual conference of the Society of Nuclear Medicine (India) on molecular imaging and targeted radionuclide therapy: predicting the future; Chandigarh (India); 11-14 Nov 2010, Chandigarh, 2010.
    Published
Conference poster
  1. Moothedathu Raynold, Aji Alex; Ormonde, B.; Yovtchev, Nicole; Barão, Marta; Ferreira, Lino. "Engineering extracellular vesicles with polymer brushes: application for the development of anti- ageing therapies". Paper presented in 3rd RESETageing Conference, 2023.
  2. Moothedathu Raynold, Aji Alex. "Engineered extracellular vesicles for gene delivery applications". Paper presented in XXVII winter school of pure and applied biophysics conducted by international society for extracellular vesicles in Venice , Italy., 2023.
  3. Moothedathu Raynold, Aji Alex. "‘Polymer brush based vectors for oligonucleotide delivery in 3D hydrogels’". Paper presented in Advanced Functional Polymers for Medicine (AFPM) 2019 international conference held at Aalto University, Espoo, Finland from 05 th - 07 th June 2019, 2019.
  4. Moothedathu Raynold, Aji Alex. "' Polymeric nanoparticles for co-delivery of siRNA and anticancer drugs'". Paper presented in Industry day conducted at IIT Delhi (India), 2017.
  5. Moothedathu Raynold, Aji Alex. "Development of efficient and stable micelles for co-delivery of drug and siRNA in cancer therapy’". Paper presented in 13th Annual Open House held at Indian Institute of Technology Delhi, India on 22nd April 2017, 2017.
  6. Moothedathu Raynold, Aji Alex. "‘Click modified amphiphilic graft copolymeric micelles of poly (styrene-alt-maleic anhydride) for combinatorial delivery of doxorubicin and plk 1 siRNA in cancer therapy’". Paper presented in 1st Annual Conference of Indian Society of Nanomedicine held at All India Institute of Medical Science, New Delhi, India from 24th-26th November 2016 (Received best poster award), 2016.
  7. Moothedathu Raynold, Aji Alex. "‘Development of poly (styrene-alt-maleic anhydride) based nanocarriers for intracellular gene delivery’". Paper presented in 13 th International symposium on bioscience and nanotechnology held at Bio-Nano Electronics Research Center, Toyo University, Japan from 26th- 28 th November 2015, 2015.
  8. Moothedathu Raynold, Aji Alex. "Poster presentation titled ‘Synthesis and evaluation of poly (styrene-alt-maleic anhydride) based nanocarriers for gene delivery application’". Paper presented in International Conference on Polymeric Biomaterials, Bioengineering & Biodiagnostics held at New Delhi, India from 27th- 30 th October 2014., 2014.
Journal article
  1. Ingabire, Diane; Qin, Chaolong; Meng, Tuo; Raynold, Aji Alex Moothendathu; Sudarjat, Hadi; Townsend, E. Andrew; Pangeni, Rudra; et al. "Nor-LAAM loaded PLGA microparticles for treating opioid use disorder". Journal of Controlled Release 373 (2024): 93-104. http://dx.doi.org/10.1016/j.jconrel.2024.06.071.
    10.1016/j.jconrel.2024.06.071
  2. Tuo Meng; Jinhua Zheng; Min Chen; Yang Zhao; Hadi Sudarjat; Aji Alex M.R.; Vineet Kulkarni; et al. "Six-month effective treatment of corneal graft rejection". Science Advances 9 12 (2023): http://dx.doi.org/10.1126/sciadv.adf4608.
    10.1126/sciadv.adf4608
  3. Ciofani, Gianni; Campisi, Marco; Mattu, Clara; Kamm, Roger D; Chiono, Valeria; Raynold, Aji Alex Moothedathu; Freitas, João S; et al. "Roadmap on nanomedicine for the central nervous system". Journal of Physics: Materials 6 2 (2023): 022501. http://dx.doi.org/10.1088/2515-7639/acab88.
    10.1088/2515-7639/acab88
  4. Moothedathu Raynold, Aji Alex; Li, Danyang; Chang, Lan; Gautrot, Julien E.. Corresponding author: Gautrot, Julien E.. "Competitive binding and molecular crowding regulate the cytoplasmic interactome of non-viral polymeric gene delivery vectors". Nature Communications 12 1 (2021): http://dx.doi.org/10.1038/s41467-021-26695-w.
    10.1038/s41467-021-26695-w
  5. "LC-MS/MS method for simultaneous quantification of dexamethasone and tobramycin in rabbit ocular biofluids". Journal of Chromatography B 1170 (2021): 122610-122610. http://dx.doi.org/10.1016/j.jchromb.2021.122610.
    10.1016/j.jchromb.2021.122610
  6. "3D engineering for optic neuropathy treatment". Drug Discovery Today 26 1 (2021): 181-188. http://dx.doi.org/10.1016/j.drudis.2020.09.034.
    10.1016/j.drudis.2020.09.034
  7. Raynold, Aji. "Comparative Assessment of Active Targeted Redox Sensitive Polymersomes Based on pPEGMA-S-S-PLA Diblock Copolymer with Marketed Nanoformulation". Biomacromolecules 19 7 (2018): 2549-2566. https://doi.org/10.1021/acs.biomac.8b00178.
    10.1021/acs.biomac.8b00178
  8. Chetan Nehate; Aji Alex Moothedathu Raynold; Veena Koul. "ATRP fabricated and short chain polyethyleneimine grafted redox sensitive polymeric nanoparticles for co-delivery of anticancer drug and siRNA in cancer therapy". ACS Applied Materials & Interfaces (2017): https://doi.org/10.1021%2Facsami.7b11716.
    10.1021/acsami.7b11716
  9. M.R. Aji Alex; Chetan Nehate; Srivani Veeranarayanan; D. Sakthi Kumar; Ritu Kulshreshtha; Veena Koul. "Self assembled dual responsive micelles stabilized with protein for co-delivery of drug and siRNA in cancer therapy". Biomaterials 133 (2017): 94-106. https://doi.org/10.1016%2Fj.biomaterials.2017.04.022.
    10.1016/j.biomaterials.2017.04.022
  10. Chetan Nehate; M.R. Aji Alex; Arun Kumar; Veena Koul. "Combinatorial delivery of superparamagnetic iron oxide nanoparticles (¿Fe 2 O 3 ) and doxorubicin using folate conjugated redox sensitive multiblock polymeric nanocarriers for enhancing the chemotherapeutic efficacy in cancer cells". Materials Science and Engineering: C 75 (2017): 1128-1143. https://doi.org/10.1016/j.msec.2017.03.024.
    10.1016/j.msec.2017.03.024
  11. Arun Kumar; Shantanu V. Lale; M.R. Aji Alex; Veena Choudhary; Veena Koul. "Folic acid and trastuzumab conjugated redox responsive random multiblock copolymeric nanocarriers for breast cancer therapy: In-vitro and in-vivo studies". Colloids and Surfaces B: Biointerfaces 149 (2017): 369-378. https://doi.org/10.1016%2Fj.colsurfb.2016.10.044.
    10.1016/j.colsurfb.2016.10.044
  12. M. R. Aji Alex; Srivani Veeranarayanan; Aby Cheruvathoor Poulose; Chetan Nehate; D. Sakthi Kumar; Veena Koul. "Click modified amphiphilic graft copolymeric micelles of poly(styrene-alt-maleic anhydride) for combinatorial delivery of doxorubicin and plk-1 siRNA in cancer therapy". J. Mater. Chem. B 4 45 (2016): 7303-7313. https://doi.org/10.1039%2Fc6tb02094a.
    10.1039/c6tb02094a
  13. Pramod, K.; Aji Alex, M.R.; Singh, M.; Dang, S.; Ansari, S.H.; Ali, J.. "Eugenol nanocapsule for enhanced therapeutic activity against periodontal infections". Journal of Drug Targeting 24 1 (2016): 24-33. http://www.scopus.com/inward/record.url?eid=2-s2.0-84955115014&partnerID=MN8TOARS.
    10.3109/1061186X.2015.1052071
  14. Baby, J.N.; Pramod, K.; John, S.; Aji Alex, M.R.; Suneesh, C.V.; Tahir, M.A.. "Quantification of zinc and lithium in zinc oxide quantum dots by atomic absorption spectroscopy". Research Journal of Pharmaceutical, Biological and Chemical Sciences 6 6 (2015): 973-977. http://www.scopus.com/inward/record.url?eid=2-s2.0-84951729927&partnerID=MN8TOARS.
  15. Baby, J.N.; Pramod, K.; John, S.; Aji Alex, M.R.; Suneesh, C.V.; Kapoor, S.; Tahir, M.A.. "Preparation and evaluation of tunable emission zinc oxide quantum dots for gene delivery". International Journal of Pharmaceutical Sciences Review and Research 35 1 (2015): 191-194. http://www.scopus.com/inward/record.url?eid=2-s2.0-84949647796&partnerID=MN8TOARS.
  16. Aji Alex, M.R.; Nagpal, N.; Kulshreshtha, R.; Koul, V.. "Synthesis and evaluation of cationically modified poly(styrene-alt-maleic anhydride) nanocarriers for intracellular gene delivery". RSC Advances 5 28 (2015): 21931-21944. http://www.scopus.com/inward/record.url?eid=2-s2.0-84923902351&partnerID=MN8TOARS.
    10.1039/c5ra00409h
  17. Alex, A.; Paul, W.; Chacko, A.J.; Sharma, C.P.. "Enhanced delivery of lopinavir to the CNS using Compritol ®-based solid lipid nanoparticles". Therapeutic Delivery 2 1 (2011): 25-35. http://www.scopus.com/inward/record.url?eid=2-s2.0-79954567170&partnerID=MN8TOARS.
    10.4155/tde.10.96
  18. Aji Alex, M.R.; Chacko, A.J.; Jose, S.; Souto, E.B.. "Lopinavir loaded solid lipid nanoparticles (SLN) for intestinal lymphatic targeting". European Journal of Pharmaceutical Sciences 42 1-2 (2011): 11-18. http://www.scopus.com/inward/record.url?eid=2-s2.0-78650678527&partnerID=MN8TOARS.
    10.1016/j.ejps.2010.10.002

Intellectual property

Patent
  1. Qingguo XuCharles O'KEEFFEXiuling LuAndré O'Reilly BERINGHSAji Alex Moothedathu RAYNOLDHadi SUDARJATZixuan ZHEN. 2023. "FORMULATIONS FOR ADMINISTERING LAAM, norLAAM AND dinorLAAM AND METHODS OF THEIR USE TO TREAT OPIOID USE DISORDER(https://patents.google.com/patent/WO2023225630A2/en)". United States.
    Pending
  2. Raynold, Aji; Veena Koul. 2023. "Stimuli sensitive polymeric nanosystems for co-delivery of drugs and nucleic acids (Granted on 20-9-2023; https://iprsearch.ipindia.gov.in/PublicSearch/PublicationSearch/Eregister) Patent number 453176". India.
    Granted/Issued
  3. Qingguo XuChaolong QINTuo MENGAji Alex Moothedathu RAYNOLDMatthew BANKS. 2023. "Sustained release formulations and methods of use thereof (https://patents.google.com/patent/WO2023150246A1/en?inventor=Aji+Alex+Moothedathu+RAYNOLD)". United States.
    Pending
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2024/05/22 Modulating the surface charge and composition of small extracellular vesicles (sEVs) using polymer brushes for biomedical applications
Centre for neurosciences and cell biology (CNC), University of Coimbra (Portugal)
2022/05/03 Gene Delivery using polymer brushes
Centre for neurosciences and cell biology (CNC), University of Coimbra (Coimbra, Portugal)
2021/10/05 Bioequivalence study of TOBRADEX ointment vs generic ointments using rabbit model FDA meeting at Virginia Commonwealth University United States
FDA United States (Richmond Virginia, United States)
2021/02/08 Participated in a one week course 'Training in Neurotherapeutics Discovery and Development for Academic Scientists course ' which is annually conducted in United States (https://www.neurotherapeuticscourse.org/). I have orally presented the Significance of polymeric nanosystems as neurotherapeutic drug delivery platforms. Training in Neurotherapeutics Discovery and Development for Academic Scientists course
2019/07/22 Design of in situ crosslinkable RNA delivery scaffolds based on high efficiency polymer brush vectors Invited oral presentation at RIKEN Japan
RIKEN 2-1 Hirosawa, Wako, Saitama, Japan 351-0198 (Saitama, Japan)
2019/03/29 Design of in situ injectable hydrogel matrix tethered with multifunctional polymeric vectors for combinatorial delivery of miRNAs and growth factor for intervertebral disc repair EDGE fellowship programme by Trinity College Dublin
Trinity College Dublin (Ireland)
2018/10/04 Gene delivery using polymer brush based vectors Commonwealth Rutherford Event 2018
Commonwealth Secretariat Commission (CSC), United Kingdom (London, United Kingdom)
2017/09/20 Development of cationic nanosystems for co-delivery of drug and siRNA in cancer therapy Open PhD defence at Indian Institute of Technology Delhi
Indian Institute of Technology Delhi India (Delhi, India)
2015/10/01 Oral presentation titled ‘Designing of safe and effective polymeric nanocarriers for delivery of drugs and genes in cancer therapy’ at the ACS on Campus event held at Indian Institute of Technology Delhi, India on 1st October 2015. ACS on Campus event
Indian Institute of Technology Delhi (Delhi, India)
2009/12/19 Lopinavir loaded solid lipid nanoparticles for intestinal lymphatic targeting Open defense of MSc thesis at Mahatma Gandhi University, Kerala, India
Mahatma Gandhi University Kerala India (Kottayam, India)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2023/05/02 - Current Supervising the thesis of a MSc student in the surface engineering of exosomes for biomedical applications at CNC, University of Coimbra
Supervisor

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2024/02/07 - 2024/02/09 Participated in the first HANDS-ON WORKSHOP: “Single Extracellular Vesicles analysis” jointly organized by the French Society of Extracellular Vesicles and the French Association of Cytometry.
Workshop
 HANDS-ON WORKSHOP: “Single Extracellular Vesicles analysis”
French Society of Extracellular Vesicles , France
2023/12/06 - 2023/12/07 Presented a poster titled 'Engineering extracellular vesicles with polymer brushes: application for the development of anti-ageing therapies'
Conference
 3rd RESETageing Conference
2023/02/06 - 2023/02/10 Participated and presented a poster titled ' Engineered extracellular vesicles for gene delivery applications' at XXVII winter school of pure and applied biophysics conducted by international society for extracellular vesicles in Venice , Italy.
Conference
 Extracellular vesicles : from biophysical to translational challenges
Istituto di Biofisica Consiglio Nazionale delle Ricerche Sede secondaria di Palermo, Italy
2022/11/07 - 2023/01/09 Participated in 'Science is Wonderful' competition conducted by European Commission to initiate collaboration of school teachers with MSCA researchers and given lectures to high school students about research in nanotechnology (https://event.scienceiswonderful.eu/event/competition)
Other
 Science is wonderful competition
European Commission, Belgium
2022/10/10 - 2022/10/16 Participated as a team member from Centre for Neurosciences and Cell Biology (CNC), University of Coimbra and conducted a scientific workshop covering the aspects of blood brain barrier, ageing and neurotherapeutics at FIC.A - International Science Festival 2022 (https://gulbenkian.pt/ciencia/agenda/fica-festival-internacional-ciencia/), which took place between October 10th and 16th, in Oeiras (Portugal).
Workshop
 FIC.A - International Science Festival 2022
2022/09/22 - 2022/09/23 European Researchers Night conducted at Coimbra, Portugal on 23rd September 2022. I was a member of team from Centre for neuroscience and cell biology (CNC), University of Coimbra and participated in the activities like demonstration of blood brain barrier, using artificially designed geometrical structures, to the audience.
Exhibition
 European Researchers Night
Universidade de Coimbra, Portugal
2019/06/05 - 2019/06/07 Poster presentation titled ‘Polymer brush based vectors for oligonucleotide delivery in 3D hydrogels’ in Advanced Functional Polymers for Medicine (AFPM) 2019 international conference held at Aalto University, Espoo, Finland from 05 th - 07 th June 2019
Conference
 Advanced functional polymers for medicine (AFPM) 2019
Aalto-yliopisto, Finland
2017/09/23 - 2017/09/23 Participated and presented poster titled ' Polymeric nanoparticles for co-delivery of siRNA and anticancer drugs' during Industry day conducted at IIT Delhi (India)
Workshop
 Industry Day
Indian Institute of Technology Delhi, India
2017/04/21 - 2017/04/22 Poster presentation titled ‘Development of efficient and stable micelles for co-delivery of drug and siRNA in cancer therapy’ in 13th Annual Open House held at Indian Institute of Technology Delhi, India on 22nd April 2017
Exhibition
 13th Annual Open House
Indian Institute of Technology Delhi Center for Biomedical Engineering, India
2016/11/24 - 2016/11/26 Poster presentation titled ‘Click modified amphiphilic graft copolymeric micelles of poly (styrene-alt-maleic anhydride) for combinatorial delivery of doxorubicin and plk 1 siRNA in cancer therapy’ in 1st Annual Conference of Indian Society of Nanomedicine held at All India Institute of Medical Science, New Delhi, India from 24th-26th November 2016 (Received best poster award)
Conference
 1st Annual Conference of Indian Society of Nanomedicine
All India Institute of Medical Sciences, India
2015/11/26 - 2015/11/28 Poster presentation titled ‘Development of poly (styrene-alt-maleic anhydride) based nanocarriers for intracellular gene delivery’ in the 13 th International symposium on bioscience and nanotechnology held at Bio-Nano Electronics Research Center, Toyo University, Japan from 26th- 28 th November 2015.
Symposium
 13 th International symposium on bioscience and nanotechnology
Toyo Daigaku Shakai Gakubu Daigakuin Shakaigaku Kenkyuka Shakai Shinrigaku, Japan
2015/11/04 - 2015/11/04 Participated in Indo-Japan Symposium - PIKNIKH Series VII (https://web.iitd.ac.in/~sundar/meeting/piknikh2015-2/participants.html) INDIAN INSTITUTE OF TECHNOLOGY DELHI NOVEMBER 04, 2015
Conference
 Indo-Japan Symposium - PIKNIKH Series VII INDIAN INSTITUTE OF TECHNOLOGY DELHI NOVEMBER 04, 2015
Indian Institute of Technology Delhi, India
2014/10/27 - 2014/10/30 Poster presentation titled ‘Synthesis and evaluation of poly (styrene-alt-maleic anhydride) based nanocarriers for gene delivery application’ in International Conference on Polymeric Biomaterials, Bioengineering & Biodiagnostics held at New Delhi, India from 27th- 30 th October 2014.
Conference
 International Conference on Polymeric Biomaterials, Bioengineering & Biodiagnostics
2014/04/14 - 2014/04/15 Poster presentation titled ‘Design and development of smart polymeric nanoparticles for overcoming chemotherapy in cancer’. 10th Annual Open House, Indian Institute of Technology Delhi, 14th April, 2010. •
Exhibition
 10th Annual Open House
Indian Institute of Technology Delhi, India
2010/11/11 - 2010/11/14 Participated in the nuclear medicine conference conducted by The Society of Nuclear Medicine-India (SNMI) at the at the Postgraduate Institute of Medical Education & Research (PGIMER), Chandigarh, India and presented posters detailing pharmacoscintigraphic studies of pharmaceutical formulations (https://humanhealth.iaea.org/HHW/NuclearMedicine/Nuclear_Medicine_Events/Archive2010/SNMICON2010/index.htm)(https://www.osti.gov/etdeweb/biblio/21414523 ; https://www.osti.gov/etdeweb/biblio/21414518)
Conference
 SNMICON2010 (https://humanhealth.iaea.org/HHW/NuclearMedicine/Nuclear_Medicine_Events/Archive2010/SNMICON2010/index.html)
Post Graduate Institute of Medical Education and Research, India

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2023/10/24 MSc thesis titled 'DEVELOPMENT OF A STRATEGY FOR A TARGETED DELIVERY OF EXTRACELLULAR VESICLES TO THE INFARCTED HEARTDEVELOPMENT OF A STRATEGY FOR A TARGETED DELIVERY OF EXTRACELLULAR VESICLES TO THE INFARCTED HEART' Quelia Ribeiro (Master)

Ad Hoc journal article review

Journal title (ISSN) Publisher
2024/06/18 - Current Biomolecules MDPI
2024/06/08 - Current Biotechnology letters (BILE) Springer
2023/10/29 - Current Journal of Controlled Release Elsevier
2022/09/01 - Current Drug delivery and translational research Springer
2020/06/02 - Current Journal of Drug Delivery Science and Technology Elsevier

Association member

Society Organization name Role
2024/05/01 - Current Marie Curie Alumni Association MSCA alumni who has completed individual MSCA postdoctoral fellowship
2024/01/02 - Current American Chemical Society (BIOT Division) Member
2021/10/21 - Current American Association of Pharmaceutical Scientists Member
2018/04/01 - Current Member of Commonwealth fellows alumini (Commonwealth Secretariat, United Kingdom) association Commonwealth Rutherford fellow alumini
2017/11/04 - Current Member of IIT Delhi Alumini association Member of alumini association of Indian Institute of Technology, Delhi (India)
2009/07/12 - Current Member and licensed pharmacist of Kerala state pharmacy council (Kerala, India) Member of state pharmacy council which is an association of licensed pharmacists from the state of Kerala, India

Committee member

Activity description
Role 		Institution / Organization
2015/06/01 - 2015/12/31 Elected representative of Nalanda hostel Indian Institute of Delhi (India) Campus during the year 2015
Coordinator
 Indian Institute of Technology Delhi, India
2014/04/19 - 2014/04/19 Student Coordinator from Centre for Biomedical Engineering, IIT, Delhi during the Annual Open House Workshop 2014-2015 conducted at IIT Delhi.
Coordinator
 Indian Institute of Technology Delhi, India

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2023/11/29 - Current 2023 -2024 Regenerative medicine (Master) Universidade de Coimbra, Portugal
2013/01/01 - 2014/06/30 2013-2014 Industrial Biomedical Technology (Master) Indian Institute of Technology Delhi, India

Journal scientific committee

Journal title (ISSN) Publisher
2022/11/06 - Current JOVE MyJove Corp.
2022/11/02 - Current Frontiers in Medical Engineering – Medical Engineering Technologies Frontiers

Mentoring / Tutoring

Topic Student name
2023/09/17 - Current Mentoring a split site Commonwealth fellowship holder (PhD student) B.H. Jaswanth Gowda
2023/02/01 - Current Bio distribution of surface engineered exosomes (Grant ID: 101019325) Beatriz Ormonde
2018/12/01 - 2020/02/07 Development of cationic polymer brushes for efficient gene delivery applications (Grant ID: INRF-2017-179) Lan Chang
2019/01/31 - 2019/06/30 Polymer brush grafting on glass surfaces and evaluation of the kinetics of RNA binding Alina Popovici
2017/09/20 - 2018/03/07 Artificial skin (Bio-inspired bi-layer polymeric hybrid scaffold) for burn injuries and trauma care (Grant ID: F.NO.41-2/2015-T.S.I (PT) (ANN.I SL.24) Thanusha A V, Gopendra Singh
2017/04/05 - 2018/03/07 Development of hybrid polymeric nanosystems for combinatorial targeted delivery of siRNA and drug in breast cancer therapy (Grant ID: BT/PR10191/NNT//28/717/2013) Chetan Nehate

Other jury / evaluation

Activity description Institution / Organization
2023/10/20 - 2023/10/20 Acted as a Jury member to recruit a research assistant at CNC, University of Coimbra in a EU funded project (Piezo4spine) Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia, Portugal
2023/08/01 - 2023/08/01 I served as the head of jury (as principal investigator) in FCT exploratory project (2022.02803.PTDC ) to recruit a MSc student researcher Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia, Portugal

Scientific expedition

Activity description Institution / Organization
2015/11/18 - 2016/02/15 I have done research on co-delivery of PLK-1 siRNA and Doxorubicin using core shell polymeric nanoparticles. Bio-Nano Electronics Research Centre (BNERC) Toyo University Japan, Japan
2009/03/31 - 2009/12/31 I have done research on the targeting of solid lipid nanoparticles loaded with anti retroviral drug to central nervous system (CNS). Sree Chitra Tirunal Institute for Medical Sciences and Technology (SCTIMST), India
Distinctions

Award

2022 Exploratory research grant (50000 Euros) by FCT (Portugal)
Fundação para a Ciência e a Tecnologia, Portugal
2021 Marie Sklodowska-Curie Individual fellowship
European Union, Belgium
2020 Seal of excellence award
2019 Seal of excellence award
European Union, Belgium
2018 Commonwealth Rutherford Fellowship in the year 2018
Commonwealth Secretariat, United Kingdom
2017 Dogra Educational Endowment Gold Medal for the best scientific publication from Centre for Biomedical Engineering, IIT Delhi in the year 2016-2017. •
Indian Institute of Technology Delhi, India
2016 Best poster presentation award at Nanobioteck conference conducted at All India Institute of Medical Sciences (AIIMS), New Delhi, India, November 2016. •
All India Institute of Medical Sciences, India
2011 Indian Institute of Technology Delhi Research Scholar Fellowship (INR 4,32,000 annually) from January 2011 - December 2015
Indian Institute of Technology Delhi, India
2007 GATE Research Scholarship (INR 96,000 annually) from All India Council for Technical Education (AICTE), Government of India from October 2007 - December 2009
All India Council for Technical Education, India

Other distinction

2022 Highly commended research article (https://cscuk.fcdo.gov.uk/meet-the-2022-csc-research-impact-award-winners/
Commonwealth Scholarship Commission, United Kingdom