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Mario Aguilar Aragon. Is Postdoc in Fundação Champalimaud. Works in the area(s) of Natural sciences with emphasis on Biological Sciences with emphasis on Cell Biology.
Identification

Personal identification

Full name
Mario Aguilar Aragon

Citation names

  • Aguilar-Aragon, Mario
  • Mario Aguilar-Aragon

Author identifiers

Ciência ID
9013-6B88-6E5A
ORCID iD
0000-0002-0018-3981
Google Scholar ID
mario aguilar-aragon

Telephones

Mobile phone
  • 910929780 (Personal)

Addresses

  • Av. Bombeiros Voluntarios, de Alges 46 S/L, 1495-021, Alges, Oeiras, Portugal (Personal)

Knowledge fields

  • Natural sciences - Biological Sciences - Cell Biology

Languages

Language Speaking Reading Writing Listening Peer-review
Spanish; Castilian (Mother tongue)
English Advanced (C1) Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2)
Portuguese Proficiency (C2) Proficiency (C2) Upper intermediate (B2) Proficiency (C2) Proficiency (C2)
Education
Degree Classification
2017/09/01 - 2018/08/31
Concluded
 Core Teaching Practises (Postgraduate Certificate)
University College London School of Life and Medical Sciences, United Kingdom
2008/09/01 - 2013/04/11
Concluded
 PhD. Developmental Biology (Doctor)
Centro Andaluz de Biología del Desarrollo, Spain

Universidad Pablo de Olavide Departamento de Biología Molecular e Ingeniería Bioquímica, Spain
Cum Laude
2008/09/01 - 2009/06/29
Concluded
 MSc in Biotechnology (Master)
Universidad Pablo de Olavide Departamento de Biología Molecular e Ingeniería Bioquímica, Spain
2002/09/21 - 2007/09/21
Concluded
 Biology (Bachelor)
Universidad de Sevilla Facultad de Biología, Spain
Affiliation

Science

Category
Host institution 		Employer
2019/05/01 - Current Postdoc (Research) Fundação Champalimaud, Portugal
Fundação Champalimaud, Portugal
2013/05/01 - 2019/02/28 Postdoc (Research) Francis Crick Institute, United Kingdom
Francis Crick Institute, United Kingdom
Outputs

Publications

Conference poster
  1. Mario Aguilar-Aragon. "Mechanical cell competition in health and disease". Paper presented in Champalimaud Foundation and the Portuguese Society for Developmental Biology: From Developmental Biology to Medicine and back, 2019.
  2. Mario Aguilar-Aragon. "Mechanical cell competition in health and disease". Paper presented in Portuguese Drosophila Meeting, 2019.
  3. Mario Aguilar-Aragon. "Mechanical cell competition in health and disease". Paper presented in Champalimaud Symposium: Tissue environment in health and disease, 2019.
  4. Mario Aguilar-Aragon. "Regulation of Crumbs trafficking in epithelia". Paper presented in British Society for Developmental Biology Spring Meeting, 2018.
  5. Mario Aguilar-Aragon. "Cdc42 maintains epithelial cell polarity via dual-kinase mechanism". Paper presented in European Drosophila Research Conference, 2017.
    10.1109/ismvl.2003.1201384
  6. Mario Aguilar-Aragon. "Cdc42 maintains epithelial cell polarity via dual-kinase mechanism". Paper presented in European Molecular Biology Organization- European Molecular Biology Laboratory Symposium: Mechanical Forces in Biology, 2017.
  7. Mario Aguilar-Aragon. "Role and regulation of Cdc42 in epithelial cell polarity". Paper presented in Gordon-Kenan Research Seminar: Cell Polarity Signaling, 2016.
  8. Mario Aguilar-Aragon. "Role and regulation of Cdc42 in epithelial cell polarity". Paper presented in Gordon Research Conference: Cell Polarity Signaling, 2016.
  9. Mario Aguilar-Aragon. "The possible feedback between the polarity determinants and the junctions in Drosophila epithelial cells". Paper presented in European Social Funds- European Molecular Biology Organization Conference: Cell Polarity and Membrane Trafficking, 2015.
  10. Mario Aguilar-Aragon. "Requirement of different Cv-c/DLC RhoGAP protein domains for epithelial morphogenesis". Paper presented in European Drosophila Research Conference, 2013.
  11. Mario Aguilar-Aragon. "Forces shaping a Hox morphogenetic gene-network". Paper presented in Spanish Society for Developmental Biology, 2012.
  12. Mario Aguilar-Aragon. "Cooption of Cv-cRhoGAP to invaginating epithelia required the recruitment of common compensatory mechanisms during the development of different organs". Paper presented in European Drosophila Research Conference, 2011.
  13. Mario Aguilar-Aragon. "Rho-downregulation by the RhoGAP Cv-c during epithelial morphogenesis required the recruitment of compensatory mechanism". Paper presented in Joint Meeting of the Portuguese and Spanish Developmenta Biology Societies, 2010.
  14. Mario Aguilar-Aragon. "Rho-downregulation by the RhoGAP Cv-c during epithelial morphogenesis required the recruitment of compensatory mechanism". Paper presented in European Molecular Biology Organization- European Social Funds Symposium: Emergent Properties of the cytoskeleton, 2010.
Journal article
  1. Aguilar-Aragon, Mario; Bonello, Teresa T; Bell, Graham P; Fletcher, Georgina C; Thompson, Barry J. "Adherens junction remodelling during mitotic rounding of pseudostratified epithelial cells". EMBO reports (2020): http://dx.doi.org/10.15252/embr.201949700.
    10.15252/embr.201949700
  2. Aguilar-Aragon, M.; Fletcher, G.; Thompson, B.J.. "The cytoskeletal motor proteins Dynein and MyoV direct apical transport of Crumbs". Developmental Biology (2019): http://dx.doi.org/10.1016/j.ydbio.2019.12.009.
    Published • 10.1016/j.ydbio.2019.12.009
  3. Borreguero-Muñoz, Nerea; Fletcher, Georgina C.; Aguilar-Aragon, Mario; Elbediwy, Ahmed; Vincent-Mistiaen, Zoé I.; Thompson, Barry J.. "The Hippo pathway integrates PI3K–Akt signals with mechanical and polarity cues to control tissue growth". PLOS Biology 17 10 (2019): e3000509. http://dx.doi.org/10.1371/journal.pbio.3000509.
    Published • 10.1371/journal.pbio.3000509
  4. Sotillos, Sol; Aguilar-Aragon, Mario; Hombría, James Castelli-Gair. "Functional analysis of the Drosophila RhoGAP Cv-c protein and its equivalence to the human DLC3 and DLC1 proteins". Scientific Reports 8 1 (2018): http://dx.doi.org/10.1038/s41598-018-22794-9.
    Published • 10.1038/s41598-018-22794-9
  5. Fletcher, Georgina C.; Diaz-de-la-Loza, Maria-del-Carmen; Borreguero-Muñoz, Nerea; Holder, Maxine; Aguilar-Aragon, Mario; Thompson, Barry J.. "Mechanical strain regulates the Hippo pathway in Drosophila". Development 145 5 (2018): dev159467. http://dx.doi.org/10.1242/dev.159467.
    10.1242/dev.159467
  6. Aguilar-Aragon, Mario; Elbediwy, Ahmed; Foglizzo, Valentina; Fletcher, Georgina C.; Li, Vivian S.W.; Thompson, Barry J.. "Pak1 Kinase Maintains Apical Membrane Identity in Epithelia". Cell Reports 22 7 (2018): 1639-1646. http://dx.doi.org/10.1016/j.celrep.2018.01.060.
    10.1016/j.celrep.2018.01.060
  7. Sotillos, Sol; Aguilar, Mario; Castelli-Gair Hombría, James. "Forces shaping a Hox morphogenetic gene network". Proceedings of the National Academy of Sciences 110 11 (2013): 4303-4308. http://dx.doi.org/10.1073/pnas.1212970110.
    Published • 10.1073/pnas.1212970110
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2017/06 Cdc42 maintains epithelial polarity via dual-kinase mechanism Cell polarity and membrane dynamics
European Molecular Biology Organization (Sant Feliu de Guixols, Spain)
2012/04 CvcRhoGAP contribution to shaping the organogenesis network PhD and PostDoc Symposium From Cells to Organs
Molecular Biology Institute of Barcelona (Barcelona, Spain)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2016/06/01 - 2016/08/31 Identification of Hippo kinase inhibitors
Co-supervisor
 14-week summer internship (Master)
Ecole Nationale Supérieure de Chimie de Montpellier, France

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2017/09/22 - 2017/09/25 Helped in the organization of the meeting (2017/09/22 - 2017/09/25)
Conference (Member of the Organising Committee)

Committee member

Activity description
Role 		Institution / Organization
2018/09/22 - 2018/09/23 Participated as a panel administrator during the The Francis Crick Institute-PhD students interview to improve my leadership and management skills.
Member
 Francis Crick Institute, United Kingdom