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Catarina is currently a visiting graduate student at Sehgal Lab - University of Pennsylvania, under a Fulbright fellowship. She is a PhD student in Pharmaceutical Sciences at the Faculty of Pharmacy, University of Coimbra, doing a project about sleep disorders and disease modeling at the Center for Neurosciences and Cell Biology - Neuroendrocrinology and Aging group (CNC-UC, N&A group), headed by Cláudia Cavadas. Catarina holds a BSc degree in Biotechnology and MSc in Cell and Molecular Biology with research experience that has provided a well-rounded background in neuroscience. During her MSc thesis, at Instituto de Medicina Molecular (IMM) she gained expertise in neuroinflammation, glial cells communication and epilepsy. Afterward, she joined Megan Carey's Lab at the Champalimaud Foundation Center for the Unknown, where she was responsible for several behavior tests using optogenetics and viral tools and contributed to managing multiple projects simultaneously. In the past years, she became very interested in the Chronobiology & Sleep disorders field and began working at CNC-UC, N&A group. Her career path has made Catarina an adaptable and responsible young researcher seeking to contribute with knowledge to the Chronobiology field.
Identification

Personal identification

Full name
Catarina Isabel Carvalhas de Almeida

Citation names

  • Almeida, Catarina
  • Carvalhas-Almeida, Catarina

Author identifiers

Ciência ID
901F-0194-5041
ORCID iD
0000-0002-4942-8249

Addresses

  • Center for Neuroscience and Cell Biology. Faculdade de Medicina, Polo I, Rua Larga, Universidade de Coimbra, 3004-504, Coimbra, Coimbra, Portugal (Professional)

Websites

Knowledge fields

  • Medical and Health Sciences - Basic Medicine - Neurosciences

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Advanced (C1) Proficiency (C2) Proficiency (C2) Proficiency (C2)
Spanish; Castilian Intermediate (B1) Upper intermediate (B2) Intermediate (B1) Upper intermediate (B2)
Education
Degree Classification
2021/11/01 - 2024/12/01
Ongoing
Programa Doutoral em Ciências Farmacêuticas (Doutoramento)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2021/02/01 - 2024/02/01
Ongoing
EIT health Ageing PhD School (Doutoramento)
EIT Health, Germany
2020/02/08 - 2020/02/08
Concluded
IELTS (Diploma de especialização)
University of Cambridge, United Kingdom

British Council Portugal, Portugal
Band score 7.5 - C1
2018/10/20 - 2018/11/30
Concluded
Course on Laboratory Animal Science for Function B, (FELASA, Cat.B) (Especialização pós-licenciatura)
Fundação Champalimaud, Portugal
2016/09/10 - 2018/09/30
Concluded
Cell and Molecular Biology with Neurobiology specialization (Mestrado)
Major in Neurobiolgy
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"Relevance of astrocytes/microglia communication for NLRP3 signalling in the CNS – proof of concept in an ex vivo model of epilepsy" (THESIS/DISSERTATION)
18/20
2013/09/12 - 2016/07/29
Concluded
Biotechnology (Licenciatura)
Instituto Politécnico de Coimbra Escola Superior Agrária de Coimbra, Portugal
"Evaluate the mutation c.900_901dupGT effect of the GRN gene in immune response and autophagy: A study in heterozygous and homozygous patients" (THESIS/DISSERTATION)
15/20
2015/09/01 - 2016/02/29
Concluded
Biotechnology (Bachelor (1st cycle))
Mendelova univerzita v Brne, Czech Republic
A
Affiliation

Science

Category
Host institution
Employer
2019/12/01 - 2020/12/31 Research Assistant (Research) CNC.IBILI, Portugal
Neuroendrocrinology and Aging Group, Cavadas' Laboratory - CNC.IBILI, Portugal
2019/07/01 - 2019/11/30 Research Trainee (Research) Instituto de Medicina Molecular, Portugal
2018/10/01 - 2019/06/30 Research Assistant (Research) Fundação Champalimaud, Portugal
Megan Carey's Laboratory - Fundação Champalimaud Center for the Unknown, Portugal

Others

Category
Host institution
Employer
2017/05/01 - 2018/09/30 MSc Thesis Student Instituto de Medicina Molecular, Portugal
Ana Sebastião's Laboratory - Instituto de Medicina Molecular, Portugal
2016/04/01 - 2016/08/31 BSc Thesis Student CNC.IBILI, Portugal
Vectors and Gene Therapy Group - Center for Neurosciences and Cell Biology - CNC, Faculty of Medicine, University of Coimbra, Portugal
2015/07/01 - 2015/07/31 Summer Internship Sonae Indústria, Portugal
Projects

Contract

Designation Funders
2019/12/01 - 2020/11/30 "HEALTHYAGING 2020 (CENTR0-01-0145-FEDER-000012)"
CENTR0-01-0145-FEDER-000012
Other
CNC.IBILI, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2018/10/01 - 2019/06/30 ”Undestanding the role of climbing fiber inputs to the cerebellum” and ”Dissecting the role of cerebellar cortex vs. deep cerebellar nucleus on eyelid conditioning”.
640093
Research Technician Fellow
Fundação Champalimaud, Portugal

Megan Carey's Laboratory - Fundação Champalimaud Center for the Unknown, Portugal
Concluded
Outputs

Publications

Conference abstract
  1. Almeida, Catarina; Ribeiro, Antónia F.; Sebastião, Ana M; Cláudia A. Valente. "NLRP3 Inflammasome assembly in microglia-induced reactive astrocytes". Paper presented in XVI Meeting of the Portuguese Society for Neuroscience (SPN2019) published at the Journal Frontiers in Cell. Neurosci. doi: 10.3389/conf.fncel.2019.01.00019, Lisbon, 2019.
    Published
Conference poster
  1. "Insomnia patient-derived iPSC neurons with potential for disease modeling". Paper presented in World Sleep Congress 2022, 2022.
  2. F. Ribeiro, Antónia; Almeida, Catarina; Sebastião, Ana M; Cláudia, A. Valente. "NLRP3 Inflammasome assembly in microglia-induced reactive astrocytes". Paper presented in XVI Meeting of the Portuguese Society for Neuroscience (SPN2019), 2019.
  3. Almeida, Catarina; Ribeiro, Antónia; Sebastião, Ana M; Cláudia A. Valente. "Microglia-dependent activation of NLRP3 inflammasome within astrocytes". Paper presented in Mind-Brain College 4th Annual Meeting, 2018.
  4. Almeida, Catarina; Sebastião, Ana M; Cláudia A. Valente. "Is astrocytes/microglia communication relevant for NLRP3 signalling in the brain?". Paper presented in FENS Forum Annual Meeting - Berlin, 2018, 2018.
  5. Almeida, Catarina. "How does astrocytes/microglia communication impact NLRP3 signalling in the CNS?". Paper presented in Portuguese Glial Network - III Symposium i3S, Porto, 2018.
  6. Almeida, Catarina; Sebastião, Ana M; Cláudia A. Valente. "Relevance of astrocytes/microglia communication for NLRP3 signalling in the CNS – proof of concept in an ex vivo model of epilepsy". Paper presented in SynaNet 2nd Annual Scientific Meeting, University of Lisbon, Portugal, 2018.
Journal article
  1. Helena Leal; Catarina Carvalhas-Almeida; Ana Rita Álvaro; Cláudia Cavadas. "Modeling hypothalamic pathophysiology in vitro for metabolic, circadian, and sleep disorders". Trends in Endocrinology & Metabolism (2024): https://doi.org/10.1016/j.tem.2024.01.001.
    10.1016/j.tem.2024.01.001
  2. Catarina Carvalhas-Almeida; Joana Serra; Joaquim Moita; Cláudia Cavadas; Ana Rita Alvaro. "Understanding neuron-glia crosstalk and biological clocks in insomnia". Neuroscience & Biobehavioral Reviews (2023): http://dx.doi.org/10.1016/j.neubiorev.2023.105100.
    10.1016/j.neubiorev.2023.105100
  3. Catarina Carvalhas-Almeida; Cláudia Cavadas; Ana Rita Álvaro. "The impact of insomnia on frailty and the hallmarks of aging". Aging Clinical and Experimental Research (2022): https://doi.org/10.1007/s40520-022-02310-w.
    10.1007/s40520-022-02310-w
  4. Catarina Almeida. "Peripheral biomarkers to diagnose obstructive sleep apnea in adults: A systematic review and meta-analysis". Sleep Medicine Reviews 64 (2022): 101659-101659. http://dx.doi.org/10.1016/j.smrv.2022.101659.
    10.1016/j.smrv.2022.101659
  5. Gaspar, Laetitia S.; Hesse, Janina; Yalçin, Müge; Santos, Bárbara; Carvalhas-Almeida, Catarina; Ferreira, Mafalda; Moita, Joaquim; et al. "Long-term continuous positive airway pressure treatment ameliorates biological clock disruptions in obstructive sleep apnea". EBioMedicine 65 (2021): 103248. http://dx.doi.org/10.1016/j.ebiom.2021.103248.
    10.1016/j.ebiom.2021.103248
  6. Gaspar, Laetitia; Santos, Bárbara; Barros-Viegas, Ana T.; Cardoso, Joao; Varela Amaral, Sara; Almeida, Catarina; Cavadas, Claudia; Álvaro, Ana Rita ; Santos-Carvalho, Ana. "The Superpowers of our Sleep". Frontiers for Young Minds (2020):
    Submitted • Assistant staff
Website
  1. Almeida, Catarina. "O que é a COVID-19?" "What is COVID-19?". 2020. https://www.uc.pt/covid19/article?preview=true&key=a-bbf31d2c49.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2017/09/23 Relevance of astrocytes/microglia communication for NLRP3 signalling in the CNS – proof of concept in an ex vivo model of epilepsy IMM Neurosciences Seminar
Instituto de Medicina Molecular, University of Lisbon (Coimbra, Portugal)

Event organisation

Event name
Type of event (Role)
Institution / Organization
2019/12/15 - 2024/05/15 World Sleep Day 2020-present: Organization and Participation in the World Sleep Day related events in collaboration with Associação Portuguesa do Sono (APS). (2020/03/13 - 2024/03/20)
Other (Member of the Organising Committee)
CNC.IBILI, Portugal

Associação Portuguesa do Sono, Portugal
2017/11/01 - 2018/02/07 XLVIII Annual Meeting of the Portuguese Pharmacology Society (2018/02/05 - 2018/02/07)
Meeting (Member of the Organising Committee)
Instituto de Medicina Molecular, Portugal
2017/10/01 - 2018/01/29 Organizing Comitee of SynaNet 3rd Annual Meeting (2018/01/16 - 2018/01/18)
Meeting (Member of the Organising Committee)
Instituto de Medicina Molecular, Portugal

Event participation

Activity description
Type of event
Event name
Institution / Organization
2020/03/30 - 2020/06/30 Participated in different activities for the diagnosis of COVID-19, including sample processing, virus inactivation and RT-PCR.
Other
Volunteer for COVID-19 diagnosis at COVID-19 UC Lab, Laboratório de Análises Clínicas, University of Coimbra
Universidade de Coimbra, Portugal
2020/02/05 - 2020/02/07 L Annual Meeting of the Portuguese Pharmacology Society is the main conference in Portugal that represents the scientific progress in Experimental Pharmacology, Clinical Pharmacology and Toxicology.
Meeting
L Annual Meeting of the Portuguese Pharmacology Society
Universidade de Coimbra Faculdade de Farmácia, Portugal
2019/12/01 - 2020/01/31 The basics of Research Data Management
Other
The basics of Research Data Management
Universidade do Minho, Portugal
2019/12/19 - 2019/12/20 The CIBB meeting 2019 at the Unidade Central Polo III, University of Coimbra, helps to promote and strengthen the scientific excellence of different Research Centres located in Coimbra.
Meeting
Center for Innovative Biomedicine and Biotechnology (CIBB) Meeting
CNC.IBILI, Portugal
2019/11/21 - 2019/11/21 From Knowledge to Market, a Tech Intensive Entrepreneurship Session/ FuEL Your Ambition - Workshop is an immersive session on the potential for commercial exploration of knowledge/technology developed by groups of researchers and other entrepreneurs, bringing a Belgian company with over 50 years of experience in this technology transfer and prototyping to help scientists translate their research.
Workshop
From Knowledge to Market, a Tech Intensive Entrepreneurship Session/ FuEL Your Ambition - Workshop
Associação para a Inovação e Desenvolvimento em Ciência e Tecnologia, Portugal

Instituto Pedro Nunes, Portugal
2018/07/07 - 2018/07/11 FENS Forum Annual Meeting 2018, at Berlin, Germany is the biggest european congress for neuroscience, presenting the latest research on different neuroscience-related fields.
Congress
FENS Forum Annual Meeting
Federation of European Neuroscience Societies, Belgium
2018/06/11 - 2018/06/16 SynaNet 2018 Summer School: ”Signals from the brain” practical workshops and talks about electrophisiology, calcium imaging and techniques to study cell-to-cell communication. Fostering of international scientific collaborations. Twinning action financed by H2020 - Neurologic and Psychiatric Disorders: from synapses to networks (SynaNet), Portugal
Workshop
SynaNet 2018 Summer School: ”Signals from the brain”
Università degli Studi di Roma La Sapienza, Italy
2018/05/18 - 2018/05/18 The Portuguese Glial Network gathers portuguese researchers, as well as foreign researchers, who are interested in the role of glial cells in the function of the nervous system, in health and disease conditions.
Symposium
Portuguese Glial Network - III Symposium
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2018/02/20 - 2018/02/21 2nd Ed. of the Workshop Career Development and Soft Skills for young scientists – From Lisbon to the World is focused on training scientists to be excellent researchers and inspiring leaders. The scientific training is complemented with soft skills training, which are useful both in academic and industrial environments and was conducted by leaders from R&D Pierre Fabre, Institute Curie Paris and University College London.
Workshop
Second Edition of the Workshop Career Development and Soft Skills for young scientists – From Lisbon to the World
Instituto de Medicina Molecular, Portugal
2018/02/05 - 2018/02/07 XLVIII Annual Meeting of the Portuguese Pharmacology Society is the main conference in Portugal that represents the scientific progress in Experimental Pharmacology, Clinical Pharmacology and Toxicology.
Meeting
XLVIII Annual Meeting of the Portuguese Pharmacology Society
Universidade de Lisboa Faculdade de Medicina, Portugal
2018/01/16 - 2018/01/18 SynaNet 2nd Annual Scientific Meeting and Satellite Symposium on ”Neurologic and Psychiatric Disorders” comprises the consorciam of four different European Universities: University of Lisbon, Portugal; La Sapienza University of Rome, Italy; Kwopio University of Eastern Finland, Finland; Lancaster University, United Kingdom
Symposium
SynaNet 2nd Annual Scientific Meeting and Satellite Symposium on ”Neurologic and Psychiatric Disorders”
Instituto de Medicina Molecular, Portugal
2017/12/12 - 2017/12/14 Talks and practical workshops about the Basics of Flow Cytometry. Fostering of international scientific collaborations. Twinning action financed by H2020 - Neurologic and Psychiatric Disorders: from synapses to networks (SynaNet), Portugal
Workshop
SynaNet Winter School and Workshop on Basics of Flow Cytometry
Itä-Suomen yliopisto - Kuopion kampus, Finland
2017/10/19 - 2017/10/20 The Mind-Brain College of the University of Lisbon integrates 7 Schools (Faculdade de Ciências (FCUL), Faculdade de Farmácia (FFUL), Faculdade de Letras (FLUL), Faculdade de Medicina (FMUL), Faculdade de Psicologia (FPUL), Instituto Superior Técnico (IST) e Instituto de Ciências Socias (ICS), which organize every year a meeting to connect research centers in essential areas important to the mind and brain studies.
Meeting
3rd Students Meeting of Mind-Brain College
Universidade de Lisboa Faculdade de Medicina, Portugal
2017/09/25 - 2017/09/29 Seminars and practical courses on animal models to study neurologic diseases and behaviour and workshop on career development. Fostering of international scientific collaborations. Twinning action financed by H2020 - Neurologic and Psychiatric Disorders: from synapses to networks (SynaNet), Portugal
Workshop
SynaNet Summer School “Behavioural Models of Disease – Diverse Routes to Translation” and “Developing your Career” Workshop
Lancaster University, United Kingdom
2016/11/29 - 2016/11/29 New Perspectives in Academic Careers in Portugal held by the American Society for Microbiology is about the prospects for researchers focusing on academic careers. Additionally, they provide a workshop on Scientific Writing and Publishing for young researchers to improve their skills on writing and publishing.
Conference
New Perspectives in Academic Careers in Portugal
Universidade de Coimbra, Portugal
2016/11/18 - 2016/11/19 1st International Symposium is an event that promotes the discussion on fundamental and translational research in stem cell biology applied to the central nervous system where a group of leading researchers from all over the world discuss their work, sharing recent findings on 2D and 3D in vitro neuronal models, stem cell transplantation, in vivo gene therapy and neural tissue engineering.
Symposium
1st International Symposium ”Brain With Out Borders”
Universidade de Coimbra, Portugal
2016/07/18 - 2016/07/22 Seminars and practical hands-on workshops on Cell Culture and Tissue theoretical and practical training.
Workshop
IV Cell Culture and Tissue Training Course
Universidade de Coimbra Faculdade de Medicina, Portugal

Association member

Society Organization name Role
2018/04/01 - 2020/02/27 Portuguese Glial Network Member
Distinctions

Award

2023 Fulbright Grant for Research with the support of FCT (2023/2024)
Fulbright Portugal, Portugal
2023 Travel award from SPN to attend the FENS Forum Regional Meeting in Algarve, May 2023
Sociedade Portuguesa de Neurociências, Portugal
2023 Best graphical abstract - BEB day meeting, Coimbra, Portugal
Universidade de Coimbra, Portugal
2020 Selected for Scicare Novartis Program - Total Immersion Week
Novartis Farma SA, Portugal
2019 2nd Best Pitch From Knowledge to Market, a Tech Intensive Entrepreneurship Session/ FuEL Your Ambition - Workshop
Instituto Pedro Nunes, Portugal

Other distinction

2015 Erasmus+ Mobility Fellowship for my BSc in Biotecnology (winter semester of 2015/2016) at Mendel University, Brno, Czech Republic
Erasmus Plus, Belgium

Mendelova univerzita v Brne, Czech Republic

Instituto Politécnico de Coimbra Escola Superior Agrária de Coimbra, Portugal