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Identification

Personal identification

Full name
Abigail Filipe Ferreira

Citation names

  • Ferreira, Abigail

Author identifiers

Ciência ID
911D-B78E-03D8
ORCID iD
0000-0003-3271-6444

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Spanish; Castilian Beginner (A1) Elementary (A2) Beginner (A1) Elementary (A2)
Education
Degree Classification
2017/02 - 2021/08
Ongoing
 Química Sustentável (Doutoramento)
Universidade do Porto, Portugal

Universidade Nova de Lisboa, Portugal

Universidade de Aveiro, Portugal
2015
Concluded
 Bioquímica (Mestrado)
Universidade do Porto Faculdade de Ciências, Portugal
"Development of New Peptide-Drug Conjugates for Cancer Therapy" (THESIS/DISSERTATION)
2013
Concluded
 Bioquímica (Licenciatura)
Universidade do Porto Faculdade de Ciências, Portugal
"Experimental study on the insertion of alkynes onto biopolymers with potential application on the local therapy of Osteomyelitis" (THESIS/DISSERTATION)
Affiliation

Science

Category
Host institution 		Employer
2016/12 - 2017/05 Researcher (Research) Universidade do Porto Faculdade de Ciências, Portugal
Outputs

Publications

Journal article
  1. Abigail F. Ferreira; Rui Lapa; Nuno Vale. "Permeability of Gemcitabine and PBPK Modeling to Assess Oral Administration". Current Issues in Molecular Biology (2021): https://www.mdpi.com/1467-3045/43/3/153.
    10.3390/cimb43030153
  2. Abigail F. Ferreira; Rui Lapa; Nuno Vale. "PBPK Modeling and Simulation and Therapeutic Drug Monitoring: Possible Ways for Antibiotic Dose Adjustment". Processes (2021): https://www.mdpi.com/2227-9717/9/11/2087.
    10.3390/pr9112087
  3. Abigail F. Ferreira; Helena Martins; José Carlos Oliveira; Rui Lapa; Nuno Vale. "PBPK Modeling and Simulation of Antibiotics Amikacin, Gentamicin, Tobramycin, and Vancomycin Used in Hospital Practice". Life (2021): https://www.mdpi.com/2075-1729/11/11/1130.
    10.3390/life11111130
  4. Cristiana Correia; Abigail F. Ferreira; Joana Santos; Rui Lapa; Marjo Yliperttula; Arto Urtti; Nuno Vale. "New In Vitro-In Silico Approach for the Prediction of In Vivo Performance of Drug Combinations". Molecules (2021): https://www.mdpi.com/1420-3049/26/14/4257.
    10.3390/molecules26144257
  5. Ferreira, Abigail; Martins, Helena; Oliveira, José Carlos; Lapa, Rui; Vale, Nuno. "In silico pharmacokinetic study of vancomycin using PBPK modeling and therapeutic drug monitoring". Current Drug Metabolism 21 (2021): http://dx.doi.org/10.2174/1389200221999210101232417.
    10.2174/1389200221999210101232417
  6. Vale, Nuno; Duarte, Diana; Silva, Sara; Correia, Ana Salomé; Costa, Bárbara; Gouveia, Maria João; Ferreira, Abigail. "Cell-penetrating peptides in oncologic pharmacotherapy: A review". Pharmacological Research 162 (2020): 105231. http://dx.doi.org/10.1016/j.phrs.2020.105231.
    10.1016/j.phrs.2020.105231
  7. Ferreira, Abigail; Moreira, Sara; Lapa, Rui; Vale, Nuno. "Permeability evaluation of gemcitabine-CPP6 conjugates in Caco-2 cells". ADMET and DMPK (2020): http://dx.doi.org/10.5599/admet.882.
    10.5599/admet.882
  8. Correia, Cristiana; Xavier, Cristina P. R.; Duarte, Diana; Ferreira, Abigail; Moreira, Sara; Vasconcelos, M. Helena; Vale, Nuno. "Development of potent CPP6–gemcitabine conjugates against human prostate cancer cell line (PC-3)". RSC Medicinal Chemistry 11 2 (2020): 268-273. http://dx.doi.org/10.1039/c9md00489k.
    10.1039/c9md00489k
  9. Ferreira, Abigail; Lapa, Rui; Vale, Nuno. "Combination of Gemcitabine with Cell-Penetrating Peptides: A Pharmacokinetic Approach Using In Silico Tools". Biomolecules (2019): http://dx.doi.org/10.3390/biom9110693.
    10.3390/biom9110693
  10. Nuno Vale; Abigail F. Ferreira; Joana Matos; Paula Fresco; Maria João Gouveia. "Amino Acids in the Development of Prodrugs". Molecules (2018): http://www.mdpi.com/1420-3049/23/9/2318.
    10.3390/molecules23092318
  11. Vale, Nuno; Ferreira, Abigail; Fernandes, Iva; Alves, Cláudia; Araújo, Maria João; Mateus, Nuno; Gomes, Paula. "Gemcitabine anti-proliferative activity significantly enhanced upon conjugation with cell-penetrating peptides". Bioorganic & Medicinal Chemistry Letters 27 13 (2017): 2898-2901. http://dx.doi.org/10.1016/j.bmcl.2017.04.086.
    10.1016/j.bmcl.2017.04.086