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Sara Rafaela Mendes graduated from Biology by the Faculty of Sciences, in 2016, and completed her MSc in Medicine and Molecular by the Faculty of Medicine of University of Porto, in 2018. Currently, she is a PhD student in the Department Sport and Physical Education and the Research Center in Sports Sciences, Health Sciences and Human Development (CIDESD), at the University Institute of Maia (ISMAI) and works in the area of Sports Science with an emphasis in mechanisms that drive muscle wasting and cause fatigue, which are common in CKD.
Identification

Personal identification

Full name
Sara Rafaela Silva Mendes
Date of birth
1994/03/31
Gender
Female

Citation names

  • Mendes, Sara

Author identifiers

Ciência ID
921A-29B8-B53B
ORCID iD
0000-0003-0002-0303
Scopus Author Id
57210372628

Email addresses

  • saramendes313@gmail.com (Professional)

Addresses

  • Avenida Carlos de Oliveira Campos, 4475-690, Maia, Maia, Portugal (Professional)

Websites

Knowledge fields

  • Natural sciences - Biological Sciences - Biology
  • Natural sciences - Biological Sciences - Molecular Biology
  • Medical and Health Sciences - Basic Medicine
  • Natural sciences - Biological Sciences - Reproductive Biology
  • Medical and Health Sciences - Health Sciences - Sport and Fitness Sciences

Languages

Language Speaking Reading Writing Listening Peer-review
English Intermediate (B1) Advanced (C1) Intermediate (B1) Intermediate (B1)
Portuguese (Mother tongue)
Education
Degree Classification
2021/02/01 - 2025/02/01
Ongoing
 Sports Science (PhD) (Doutoramento)
Instituto Universitário da Maia, Portugal
2019/09/17 - 2021/01/31
Ongoing
 Técnico de Desporto/Sports Coach (Curso de Especialização Tecnológica)
Major in desporto
Fitness Academy, Portugal
2018
Concluded
 Molecular Medicine and Oncology (MSc) (Mestrado)
Major in Medicina e Oncologia Molecular.
Universidade do Porto Faculdade de Medicina, Portugal
"Unveiling novel modulators of trophoblast function" (THESIS/DISSERTATION)
 18
2016
Concluded
 Biology (BSc) (Licenciatura)
Major in Biology
Universidade do Porto Faculdade de Ciências, Portugal
"Are pipefish males able to reduce development heterogeneity within their broods?" (THESIS/DISSERTATION)
 14
Affiliation

Science

Category
Host institution 		Employer
2021/02/01 - Current Researcher (Research) Fundação para a Ciência e a Tecnologia, Portugal
Instituto Universitário da Maia, Portugal
2019/12/02 - 2021/01/31 Research Trainee (Research) Centro de Investigação em Desporto Saúde e Desenvolvimento Humano, Portugal
Instituto Universitário da Maia, Portugal
2017/02/15 - 2019/11/30 Research Trainee (Research) Ageing & Stress Group, Portugal
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2015/09/15 - 2016/12/15 Research Trainee (Research) Biology and Genetics of Reproduction, Portugal
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2014/09/15 - 2016/07/15 Research Trainee (Research) Behaviour Ecology Group, Portugal
Research Centre in Biodiversity and Genetic Resources (CIBIO), Portugal

Others

Category
Host institution 		Employer
2019/08/26 - 2021/01/31 Collaborator Fitness Up, Portugal
Fitness UP - São João, Portugal
2019/09/09 - 2019/09/14 Collaborator in the project "Como envelhece o ovário? Stress oxidativo, fibrose e inflamação". 15th Escola de Ciências da Vida e da Saúde (ECVS) Universidade do Porto Faculdade de Medicina, Portugal
2018/09/04 - 2018/09/09 Collaborator in the project "Como envelhece o ovário? Stress oxidativo, fibrose e inflamação". 14th Escola de Ciências da Vida e da Saúde (ECVS) Universidade do Porto Faculdade de Medicina, Portugal
2017/09/03 - 2017/09/08 Collaborator in the project "Envelhecimento e redução da fertilidade feminina. Serão sempre os antioxidantes heróis?". 13th Escola de Ciências da Vida e da Saúde (ECVS) Universidade do Porto Faculdade de Medicina, Portugal
Projects

Grant

Designation Funders
2021/02/01 - 2025/01/31 Skeletal muscle under assault in haemodialysis patients: impact of redox imbalance on the molecular pathophysiology of skeletal muscle wasting
2020.07740.BD
10.54499/2020.07740.BD
PhD Student Fellow
Fundação para a Ciência e a Tecnologia
Ongoing
Outputs

Publications

Conference paper
  1. Filipa Timóteo; Mendes, Sara; Rocha, N.A; Matos, Liliana; Rodrigues, Adriana R.; Almeida, Henrique; Silva, Elisabete. "Specific antioxidant effect on ovarian ageing.". Paper presented in 11th Symposium on Metabolism – Ageing & Metabolism, Porto, 2019.
    In press
  2. Mendes, Sara; Filipa Timóteo; Rodrigues, Adriana R.; Matos, Liliana; Saraiva, J.; Almeida, Henrique; Guedes-Martins, L.; Silva, Elisabete. "Maternal uterine ageing and placentation.". Paper presented in 11th Symposium on Metabolism – Ageing & Metabolism, Porto, 2019.
    In press
  3. Filipa Timóteo; Mendes, Sara; Rocha, N.A.; Matos, Liliana; Rodrigues, Adriana R.; Almeida, Henrique; Silva, Elisabete. "Improvement of age-related ovarian involution by the use of a NADPH-oxidase inhibitor.". Paper presented in 14th Young European Scientist (YES) Meeting, Porto, 2019.
    Published • 10.1097/j.pbj.0000000000000054
  4. Filipa Timóteo; Rocha, N.A.; Mendes, Sara; Rodrigues, Adriana R.; Matos, Liliana; Almeida, Henrique; Silva, Elisabete. "Female reproductive aging: exploring the effects of antioxidant treatment.". Paper presented in 13th Young European Scientist (YES) Meeting, Porto, 2018.
    Published • 10.1016/j.pbj.0000000000000032
  5. Mendes, Sara; Filipa Timóteo; Rodrigues, Adriana R.; Matos, Liliana; Saraiva, J.; Almeida, Henrique; Guedes-Martins, L.; Silva, Elisabete. "Uterine protein oxidative modifications as a contribute to defective placentation". Paper presented in 13th Young European Scientist (YES) Meeting, Porto, 2018.
    Published • 10.1016/j.pbj.0000000000000032
  6. Mendes, Sara; Soares, A.I.; Silveira, S.; Matos, Liliana; Guedes-Martins, L.; Saraiva, J.; Almeida, H.; Silva, Elisabete. "Uterine protein oxidative modifications may condition trophoblast function". Paper presented in 12th Young European Scientist (YES) Meeting, Porto, 2017.
    Published • 10.1063/1.4981982
Conference poster
  1. Mendes, Sara; Adriana Raquel Rodrigues; Tiago Duarte; Diogo V. Leal; Almeida, Henrique; Viana, João L.; Silva, Elisabete. "Nrf2 deficiency appears to trigger premature damage to the kidney before impairing skeletal muscle. A glimpse into the progression of chronic kidney disease?". Paper presented in Encontro Renal, 2023.
  2. Filipa Timóteo; Rocha, N.A.; Mendes, Sara; Rodrigues, A.R.; Matos, Liliana; Almeida, H.; Silva, Elisabete. "Effect of antioxidant supplementation in female reproductive ageing". Paper presented in 7th i3s anual meeting 2017, 2019.
  3. Mendes, Sara; Filipa Timóteo; Rodrigues, A.R.; Matos, Liliana; Saraiva, J.; Almeida, Henrique; Guedes-Martins, L.; Silva, Elisabete. "Maternal uterine ageing and placentation". Paper presented in 11th Symposium on Metabolism– Ageing & Metabolism, 2019.
  4. Filipa Timóteo; Mendes, Sara; Rocha, N.A.; Matos, Liliana; Rodrigues, A.R.; Almeida, Henrique; Silva, Elisabete Mendes. "Improvement of age - related ovarian involution by the use of a NADPH - oxidase inhibitor". Paper presented in 14th Young European Scientist (YES) Meeting, 2019.
  5. Mendes, Sara; Filipa Timóteo; Rodrigues, A.R.; Matos, Liliana; Saraiva, J.; Almeida, H.; Guedes-Martins, L.; Silva, Elisabete. "Uterine ageing: protein carbonylation and placentation". Paper presented in Ageing: models, mechanisms and therapies, 2019.
  6. Filipa Timóteo; Mendes, Sara; Rocha, N.A.; Matos, Liliana; Rodrigues, A.R.; Almeida, H.; Silva, Elisabete. "Apocynin ameliorates age-related ovarian fertility decline in mice.". Paper presented in Ageing: models, mechanisms and therapies., 2019.
  7. Mendes, Sara; Filipa Timóteo; Rodrigues, A.R.; Matos, Liliana; Saraiva, J.; Almeida, H.; Guedes-Martins, L.; Silva, Elisabete. "Uterine protein carbonylation may contribute to a defective placentation". Paper presented in 7th i3s anual meeting 2017, 2018.
  8. Mendes, Sara; Filipa Timóteo; Rodrigues, A.R.; Matos, Liliana; Saraiva, J.; Almeida, H.; Guedes-Martins, L.; Silva, Elisabete. "Uterine protein oxidative modifications as a contributor to defective placentation". Paper presented in 13th Young European Scientist (YES) Meeting, 2018.
  9. Mendes, Sara; Soares, A.I.; Silveira, S.; Matos, Liliana; Guedes-Martins, L.; Saraiva, J.; Almeida, H.; Silva, Elisabete. "Uterine protein oxidative modifications may condition trophoblast function". Paper presented in 12th Young European Scientist (YES) Meeting, 2017.
  10. Mendes, Sara; Cunha, M.; Monteiro, N.. "Standing out or blending in: are pipefish males able to reduce developmental heterogeneity within the brood pouch?". Paper presented in 9º Encontro de Investigadores Jovem da U.Porto (IJUP), 2016.
  11. Mendes, Sara; Cunha, M.; Monteiro, N.. "Can pipefish males reduce developmental heterogeneity within their broods?". Paper presented in 12ºCongresso da Sociedade Portuguesa de Etologia, 2015.
Journal article
  1. Sara Mendes; Diogo V. Leal; Luke A. Baker; Aníbal Ferreira; Alice C. Smith; João L. Viana. "The Potential Modulatory Effects of Exercise on Skeletal Muscle Redox Status in Chronic Kidney Disease". International Journal of Molecular Sciences (2023): https://doi.org/10.3390/ijms24076017.
    10.3390/ijms24076017
  2. S Mendes; Sá R; Manuel Magalhães; Franklim Marques; Sousa M; Elisabete Silva. "The Role of ROS as a Double-Edged Sword in (In)Fertility: The Impact of Cancer Treatment". Cancers (2022): https://www.mdpi.com/2072-6694/14/6/1585.
    10.3390/cancers14061585
  3. F. Timóteo-Ferreira; D. Abreu; S. Mendes; L. Matos; A.R. Rodrigues; H. Almeida; E. Silva. "Redox imbalance in age-related ovarian dysfunction and perspectives for its prevention". Ageing Research Reviews 68 (2021): 101345-101345. https://doi.org/10.1016/j.arr.2021.101345.
    10.1016/j.arr.2021.101345
  4. Mendes, S.; Timóteo-Ferreira, F.; Soares, A.I.; Rodrigues, A.R.; Silva, A.M.N.; Silveira, S.; Matos, L.; et al. "Age-related oxidative modifications to uterine albumin impair extravillous trophoblast cells function". Free Radical Biology and Medicine 152 (2020): 313-322. http://dx.doi.org/10.1016/j.freeradbiomed.2020.03.020.
    Published • 10.1016/j.freeradbiomed.2020.03.020
  5. F. Timóteo-Ferreira; S. Mendes; N. A. Rocha; L. Matos; A. R. Rodrigues; H. Almeida; E. Silva. "Apocynin Dietary Supplementation Delays Mouse Ovarian Ageing". Oxidative Medicine and Cellular Longevity (2019): https://doi.org/10.1155/2019/5316984.
    Published • 10.1155/2019/5316984
  6. Sara Mendes; Filipa Timóteo-Ferreira; Henrique Almeida; Elisabete Silva. "New Insights into the Process of Placentation and the Role of Oxidative Uterine Microenvironment". Oxidative Medicine and Cellular Longevity 2019 (2019): 1-18. https://doi.org/10.1155/2019/9174521.
    Published • 10.1155/2019/9174521
  7. Cunha, M.; Berglund, A.; Mendes, S.; Monteiro, N.. "The ‘Woman in Red’ effect: pipefish males curb pregnancies at the sight of an attractive female". Proceedings of the Royal Society B: Biological Sciences 285 1885 (2018): 20181335. http://dx.doi.org/10.1098/rspb.2018.1335.
    Published • 10.1098/rspb.2018.1335
Report
  1. Mendes, Sara. 2016. "Are pipefish males able to reduce development heterogeneity within their broods?".
Thesis / Dissertation
  1. Mendes, Sara. "Unveiling novel modulators of trophoblast function". Master, Universidade do Porto Faculdade de Medicina, 2018.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2019/10/30 Specific antioxidant effect on ovarian ageing 11th Symposium on Metabolism – Ageing & Metabolism
(Porto, Portugal)
2019/09/13 Improvement of age-related ovarian involution by the use of a NADPH-oxidase inhibitor. 14th Young European Scientist (YES) Meeting
(Porto, Portugal)
2019/07/02 Effects of antioxidant supplementation in ovarian ageing. XLIX reunião sociedade portuguesa de farmacologia, XXXVII reunião farmacologia clínica, XVIII reunião toxicologia
(Porto, Portugal)
2019/02/14 Exploring the role of uterine oxidative protein modifications in defective placentation 12º Encontro de Investigadores Jovem da U.Porto (IJUP)
(Porto, Portugal)
2019/02/14 Antioxidant supplementation. A future way for delaying ovarin ageing? 12º Encontro de Investigadores Jovem da U.Porto (IJUP)
(Porto, Portugal)
2019/02/07 Unveiling the role of uterine oxidative protein modifications as a contributor to a defective placentation XLIX reunião sociedade portuguesa de farmacologia, XXXVII reunião farmacologia clínica, XVIII reunião toxicologia
(Porto, Portugal)
2019/02/07 Effects of antioxidante supplementation in ovarian ageing. XLIX reunião sociedade portuguesa de farmacologia, XXXVII reunião farmacologia clínica, XVIII reunião toxicologia
(Porto, Portugal)
2018/09/14 Female reproductive aging: exploring the effects of antioxidant treatment 13th Young European Scientist (YES) Meeting
(Porto, Portugal)
2018/06/05 Modulation of trophoblast function by oxidative protein modification. Student’s Talk
(Porto, Portugal)
2018/02/09 Exploring the role of oxidative protein modifications in trophoblast function 11º Encontro de Investigadores Jovem da U.Porto (IJUP)
(Porto, Portugal)
2017/11/10 Dual effect of anti-oxidant treatment on reproductive ovarian aging 6th i3s anual meeting
(Póvoa de Varzim, Portugal)
2017/05/15 Brood reduction, embryo homogenization and the “women in red” effect: new perspectives in pipefish male pregnancy. 3rd Syng Bio
(Florida, United States)

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2016/11/15 - 2016/12/02 Course in Analysing Data generated from Molecular Techniques - E-learning program to learn how to analyse DNA, RNA and protein sequences through various computer programs and online software widely used during research in molecular biology, genetics, genomics, ecology, biodiversity and taxonomy.
Other
 Course in Analysing Data generated from Molecular Techniques
Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal, Portugal

Mentoring / Tutoring

Topic Student name
2017/09/15 - 2019/11/05 Theses / Dissertation: "Female fertility decline: Exploring the role of antioxidants in delaying ovarian ageing" Filipa Timóteo Ferreira
2019/09/02 - 2019/09/07 Project: "Como envelhece o ovário? Stress oxidativo, fibrose e inflamação." Ana Laura Costa; Diogo Heleno; Rita Costa.
2018/09/04 - 2018/09/09 Project: "Como envelhece o ovário? Stress oxidativo, fibrose e inflamação." Beatriz Martins; Beatriz Torres; Maria Justino Gaspar.
2017/09/03 - 2017/09/08 Project: "Envelhecimento e redução da fertilidade feminina. Serão sempre os antioxidantes heróis?" Eva Paiva; Mariana Nunes; Natacha Cantarinhas