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Rui Fernandes graduated in Biology in 1996 at Faculty of Sciences, University of Porto, and he is a PhD student at Universidade do Porto Faculdade de Medicina and the Institute for Research and Innovation in Health Sciences (i3s). He started working at Centro de Estudos de Paramiloidose, Hospital Santo António with Joana Palha and after he began a research project in the area of Familial Amyloidotic Polyneuropathy (FAP), with Professor Maria João Saraiva at the Institute for Molecular and Cell Biology (IBMC). In 2002, he started a position as the head of the Advance Tissue Analysis Facility (ATAF) at the Institute for Molecular and Cell Biology, currently Histology and Electron Microscopy (HEMS) in i3s. Rui Fernandes has participated in numerous studies, namely: conventional Ultrastructure; immunoelectromicroscopy; elemental analysis EDX; STEM among others. Published over 55 articles in peer-reviewed indexed journals.
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Identification

Personal identification

Full name
Rui Fernandes
Gender
Male

Citation names

  • Fernandes, R.
  • Rui Fernandes

Author identifiers

Ciência ID
921F-0A59-C1EA
ORCID iD
0000-0002-9535-368X
Researcher Id
S-4508-2017
Scopus Author Id
56835103600

Email addresses

  • rfernand@i3s.up.pt (Professional)

Addresses

  • I3S / IBMC - HEMS l . Rua Alfredo Allen, 208, 4200-135, Porto, Porto, Portugal (Professional)

Websites

Knowledge fields

  • Medical and Health Sciences
  • Natural sciences - Biological Sciences
  • Exact Sciences - Physical Sciences - Optics

Languages

Language Speaking Reading Writing Listening Peer-review
English Advanced (C1) Advanced (C1) Upper intermediate (B2) Advanced (C1)
French Intermediate (B1) Advanced (C1) Intermediate (B1) Upper intermediate (B2)
Spanish; Castilian Upper intermediate (B2) Advanced (C1) Elementary (A2) Upper intermediate (B2)
German Beginner (A1) Intermediate (B1) Beginner (A1) Beginner (A1)
Italian Elementary (A2) Advanced (C1) Elementary (A2) Intermediate (B1)
Portuguese (Mother tongue)
Education
Degree Classification
2019 - 2023
Ongoing
 Metabolismo - clínica e experimentação (PDMCE) (Curso de doutoramento (conclusão de unidades curriculares))
Major in “Perirenal adipocytes fueling renal carcinoma: metabolic symbiosis with macrophages and cancer cells at the tumour microenvironment invasive front?”
Universidade do Porto Faculdade de Medicina, Portugal
1992 - 1996
Concluded
 Biologia (Licenciatura)
Universidade do Porto Faculdade de Ciências, Portugal
""Solanum tuberosum L. : the influence of nitrogen nutrition and flower stem ablation on tuber nutritional quality"" (THESIS/DISSERTATION)
Affiliation

Science

Category
Host institution 		Employer
1998 - 2001 Research Trainee (Research) Instituto de Biologia Molecular e Celular, Portugal
Instituto de Biologia Molecular e Celular, Portugal
1995 - 1998 Research Trainee (Research) Universidade do Porto, Portugal
Centro Hospitalar Universitário do Porto EPE, Portugal

Teaching in Higher Education

Category
Host institution 		Employer
2017 - Current Invited Assistant Professor (University Teacher) Universidade do Porto Faculdade de Ciências, Portugal
Universidade do Porto Faculdade de Ciências, Portugal

Other Careers

Category
Host institution 		Employer
2023/01/01 - Current Técnico Superior (Técnico Superior) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2002/01/01 - 2022/12 Técnico Superior (Técnico Superior) Instituto de Biologia Molecular e Celular, Portugal
Instituto de Biologia Molecular e Celular, Portugal

Positions / Appointments

Category
Host institution 		Employer
2002/01/01 - Current Platform Head of HEMS - Histology and Electron Microscopy Instituto de Biologia Molecular e Celular, Portugal
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Projects

Grant

Designation Funders
2005/08 - 2008/01 Role of Transthyretin in A-Beta toxicity
Provided by PTCRIS: POCI/SAU-NEU/57761/2004
POCI/SAU-NEU/57761/2004
Researcher
Instituto de Biologia Molecular e Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2000 - 2001 POCTI-35785-PRO31902-BTI
POCTI-35785-PRO31902-BTI
Research Technician Fellow
Instituto de Biologia Molecular e Celular, Portugal
Concluded
1998/10 - 2000/09 Analysis of amyloid deposition in a transthyretin mice
Provided by PTCRIS: PRAXIS XXI/BTI/16723/98
 Fundação para a Ciência e a Tecnologia

Contract

Designation Funders
2019/01/01 - 2019/12/31 Instituto de Investigação e Inovação em Saúde
UID/BIM/04293/2019
Instituto Nacional de Engenharia Biomédica, Portugal

Universidade do Porto, Portugal

Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal

Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2016 - 2019 Chronological aging in pathogenic Aspergillus species
PTDC/BIA-MIC/0278/2014
Technical development
Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
Concluded
2011/01/01 - 2012/12/31 Strategic Project - LA 2 - 2011-2012
PEst-C/SAU/LA0002/2011
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal

Instituto Nacional de Engenharia Biomédica, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2007/08/01 - 2010/10/31 Identification of the mechanisms allowing central nervous system regeneration after a pre-conditioning injury to the peripheral nervous system.
PTDC/SAU-NEU/68470/2006
Technical development
Instituto de Biologia Molecular e Celular, Portugal

Instituto Nacional de Engenharia Biomédica, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2007/08/01 - 2009/12/31 Modulation of A-Beta toxicity by transthyretin in AlZheimer´s disease
PTDC/SAU-NEU/64593/2006
Provided by PTCRIS: PTDC/SAU-NEU/64593/2006
Researcher
Instituto de Biologia Molecular e Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2005 - 2007 Evaluation of cellular therapy in leukodystrophies with peripheral nervous system demyelination
Grant
Technical development
Association Européenne contre les Leucodystrophies, France
Concluded
Outputs

Publications

Book chapter
  1. Moreira-Barbosa, Catarina; Matos, Andreia; Rui Fernandes; Mendes-Ferreira, Miguel; Rodrigues, Rafaela; Cruz, Tânia; Costa, Ângela Margarida; et al. "The role of fatty acids metabolism on cancer progression and therapeutics development". In Bioactive Lipids, 101-132. Elsevier, 2023.
    10.1016/b978-0-12-824043-4.00007-5
  2. "Quantitative Proteomic Analysis of Skeletal Muscle Detergent- Resistant Membranes in a Smith-Lemli-Opitz Syndrome Mouse". In Cholesterol - Good, Bad and the Heart. 2018.
    Published
  3. Sousa, M.M.; Ferrão, J.; Fernandes, R.; Guimarães, A.; Geraldes, J.B.; Perdigoto, R.; Tomé, L.; et al. "Deposition and passage of transthyretin through the blood-nerve barrier in recipients of familial amyloid polyneuropathy livers". In Laboratory Investigation, 357-359. 2004.
    Published • 10.1038/labinvest.3700107
Conference paper
  1. Fernandes, R.; Andrade, M.T.. "Adaptation execution cost definition for a multimedia adaptation decision engine using a neural network". 2019.
    10.1063/1.5114226
  2. Rui Fernandes. "Aluminium differential effects on major pin points in Al-tolerant and Al-sensitive rye seedlings". Paper presented in 2nd Agriculture and Climate Change Conference (Elsevier)At: Sitges, Spain, 2017.
  3. Rui Fernandes; Maria Luís Cardoso. Corresponding author: Maria Luís Cardoso. "Morphological and Proteomic Studies on Smith-Lemli-O-pitz syndrome: further evidence that cholesterol deficiency causes autophagy". Paper presented in Unit-for-Multidisciplinary-Research-in-Biomedicine Summit, 2016.
Journal article
  1. Inês Tavares; Mariana Morais; Francisca Dias; Mariana Ferreira; Gabriela Martins; Rui Fernandes; Sílvia Joana Bidarra; Rui Medeiros; Ana Luísa Teixeira. "Extracellular vesicles derived-microRNAs predicting enzalutamide-resistance in 3D spheroid prostate Cancer model". International Journal of Biological Macromolecules (2024): http://dx.doi.org/10.1016/j.ijbiomac.2024.137993.
    10.1016/j.ijbiomac.2024.137993
  2. Débora Ferreira; Cátia Santos-Pereira; Marta Costa; Julieta Afonso; Sujuan Yang; Janine Hensel; Kathleen M. McAndrews; et al. "Exosomes modified with anti-MEK1 siRNA lead to an effective silencing of triple negative breast cancer cells". Biomaterials Advances 154 (2023): 213643-213643. http://dx.doi.org/10.1016/j.bioadv.2023.213643.
    10.1016/j.bioadv.2023.213643
  3. Rocha, Daniela N.; Carvalho, Eva D.; Pires, Liliana R.; Gardin, Chiara; Zanolla, Ilaria; Szewczyk, Piotr K.; Machado, Cláudia; et al. "It takes two to remyelinate: A bioengineered platform to study astrocyte-oligodendrocyte crosstalk and potential therapeutic targets in remyelination". Biomaterials Advances 151 (2023): 213429. http://dx.doi.org/10.1016/j.bioadv.2023.213429.
    10.1016/j.bioadv.2023.213429
  4. Sônia Nair Báo; Manuela Machado; Ana Luisa Da Silva; Adma Melo; Sara Cunha; Sérgio S. Sousa; Ana Rita Malheiro; et al. "Potential Biological Properties of Lycopene in a Self-Emulsifying Drug Delivery System". Molecules (2023): https://doi.org/10.3390/molecules28031219.
    10.3390/molecules28031219
  5. Sousa, Adelaide; Rufino, Ana T.; Fernandes, Rui; Malheiro, Ana; Carvalho, Félix; Fernandes, Eduarda; Freitas, Marisa. "Silver nanoparticles exert toxic effects in human monocytes and macrophages associated with the disruption of ¿¿m and release of pro-inflammatory cytokines". Archives of Toxicology 97 2 (2022): 405-420. http://dx.doi.org/10.1007/s00204-022-03415-x.
    10.1007/s00204-022-03415-x
  6. Rui Fernandes; Jelena Stevanovic-Silva; Jorge Beleza; Pedro Coxito; Hugo Rocha; Tiago Bordeira Gaspar; Fátima Gärtner; et al. "Exercise performed during pregnancy positively modulates liver metabolism and promotes mitochondrial biogenesis of female offspring in a rat model of diet-induced gestational diabetes". Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1868 11 (2022): 166526-166526. http://dx.doi.org/10.1016/j.bbadis.2022.166526.
    10.1016/j.bbadis.2022.166526
  7. Rui Fernandes; Mariana Morais; Vera Machado; Francisca Dias; Patrícia Figueiredo; Palmeira C; Gabriela Martins; et al. "Glucose-Functionalized Silver Nanoparticles as a Potential New Therapy Agent Targeting Hormone-Resistant Prostate Cancer cells". International Journal of Nanomedicine Volume 17 (2022): 4321-4337. http://dx.doi.org/10.2147/ijn.s364862.
    10.2147/ijn.s364862
  8. Sara Baptista-Silva; Beatriz G. Bernardes; Sandra Borges; Ilda Rodrigues; Rui Fernandes; Susana Gomes-Guerreiro; Marta Teixeira Pinto; et al. "Exploring Silk Sericin for Diabetic Wounds: An In Situ-Forming Hydrogel to Protect against Oxidative Stress and Improve Tissue Healing and Regeneration". Biomolecules (2022): https://doi.org/10.3390/biom12060801.
    10.3390/biom12060801
  9. Cruz, Ana Filipa; Fonseca, Nuno A.; Malheiro, Ana Rita; B. Melo, Joana; Gaspar, Maria Manuela; Rui Fernandes; Moura, Vera; Simões, Sérgio; Moreira, João Nuno. "Targeted liposomal doxorubicin/ceramides combinations: The importance to assess the nature of drug interaction beyond bulk tumor cells". European Journal of Pharmaceutics and Biopharmaceutics 172 (2022): 61-77. http://dx.doi.org/10.1016/j.ejpb.2022.01.006.
    10.1016/j.ejpb.2022.01.006
  10. de Sousa, Alexandra; AbdElgawad, Hamada; Fidalgo, Fernanda; Teixeira, Jorge; Matos, Manuela; Tamagnini, Paula; Rui Fernandes; et al. "Subcellular Compartmentalization of Aluminum Reduced its Hazardous Impact on Rye Photosynthesis". SSRN Electronic Journal (2022): http://dx.doi.org/10.2139/ssrn.4064407.
    10.2139/ssrn.4064407
  11. Nânci Santos-Ferreira; Alexandra Lianou; Ângela Alves; Maria João Cardoso; Solveig Langsrud; Ana Rita Malheiro; Rui Fernandes; et al. "Cross-contamination of lettuce with Campylobacter spp. via cooking salt during handling raw poultry". PLOS ONE (2021): https://doi.org/10.1371/journal.pone.0250980.
    10.1371/journal.pone.0250980
  12. Fernandes, Rui. "The controversial role of glucose in the diabetic kidney". Porto Biomedical Journal 6 1 (2021): e113. http://dx.doi.org/10.1097/j.pbj.0000000000000113.
    10.1097/j.pbj.0000000000000113
  13. Rodrigues, Ana Isabel Geraldes; Gudiña, Eduardo José; Abrunhosa, Luís; Malheiro, Ana R.; Fernandes, Rui; Teixeira, J. A.; Rodrigues, L. R.. "Rhamnolipids inhibit aflatoxins production in Aspergillus flavus by causing structural damages in the fungal hyphae and down-regulating the expression of their biosynthetic genes". (2021): http://hdl.handle.net/1822/72521.
    10.1016/j.ijfoodmicro.2021.109207
  14. Vilaça, Natália; Bertão, Ana Raquel; Prasetyanto, Eko Adi; Granja, Sara; Costa, Marta; Fernandes, Rui; Figueiredo, Francisco; et al. "Surface functionalization of zeolite-based drug delivery systems enhances their antitumoral activity in vivo". (2021): http://hdl.handle.net/1822/71279.
    10.1016/j.msec.2020.111721
  15. Komora, N.; Maciel, C.; Amaral, R.A.; Fernandes, R.; Castro, S.M.; Saraiva, J.A.; Teixeira, P.. "Innovative hurdle system towards Listeria monocytogenes inactivation in a fermented meat sausage model - high pressure processing assisted by bacteriophage P100 and bacteriocinogenic Pediococcus acidilactici". Food Research International 148 (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85112485252&partnerID=MN8TOARS.
    10.1016/j.foodres.2021.110628
  16. Maciel, C.; Campos, A.; Komora, N.; Pinto, C.A.; Fernandes, R.; Saraiva, J.A.; Teixeira, P.. "Impact of high hydrostatic pressure on the stability of lytic bacteriophages' cocktail Salmonelex™ towards potential application on Salmonella inactivation". LWT 151 (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85110688160&partnerID=MN8TOARS.
    10.1016/j.lwt.2021.112108
  17. Gonçalo Mesquita; Tânia Silva; Ana C. Gomes; Pedro F. Oliveira; Marco G. Alves; Rui Fernandes; Agostinho A. Almeida; Ana C. Moreira; Maria Salomé Gomes. "H-Ferritin is essential for macrophages’ capacity to store or detoxify exogenously added iron". Scientific Reports 10 1 (2020): https://doi.org/10.1038/s41598-020-59898-0.
    10.1038/s41598-020-59898-0
  18. Aureliano Fertuzinhos; Marta A. Teixeira; Miguel Goncalves Ferreira; Rui Fernandes; Rossana Correia; Ana Rita Malheiro; Paulo Flores; Andrea Zille; Nuno Dourado. "Thermo-Mechanical Behaviour of Human Nasal Cartilage". Polymers 12 1 (2020): 177-177. https://doi.org/10.3390/polym12010177.
    10.3390/polym12010177
  19. Ana Cordeiro Gomes; Ana C. Moreira; Tânia Silva; João V. Neves; Gonçalo Mesquita; Agostinho A. Almeida; Palmira Barreira-Silva; et al. "IFN-¿–Dependent Reduction of Erythrocyte Life Span Leads to Anemia during Mycobacterial Infection". The Journal of Immunology (2019): https://doi.org/10.4049/jimmunol.1900382.
    10.4049/jimmunol.1900382
  20. Vilaça, Natália; Gallo, Juan; Fernandes, Rui; Figueiredo, Francisco; Fonseca, António M; Baltazar, Fatima; Neves, Isabel Correia; et al. "Synthesis, characterization and in vitro validation of a magnetic zeolite nanocomposite with T2-MRI properties towards theranostic applications". Journal of Materials Chemistry B (2019): http://dx.doi.org/10.1039/c9tb00078j.
    10.1039/c9tb00078j
  21. Jéssica Costa; Rute Pereira; Jorge Oliveira; Ângela Alves; Ângela Marques-Magalhães; Amaro Frutuoso; Carla Leal; et al. "Structural and molecular analysis of the cancer prostate cell line PC3: Oocyte zona pellucida glycoproteins". Tissue and Cell 55 (2018): 91-106. https://doi.org/10.1016/j.tice.2018.11.001.
    10.1016/j.tice.2018.11.001
  22. Norton Komora; Carolina Bruschi; Vânia Ferreira; Cláudia Maciel; Teresa R.S. Brandão; Rui Fernandes; Jorge A. Saraiva; Sónia Marília Castro; Paula Teixeira. "The protective effect of food matrices on Listeria lytic bacteriophage P100 application towards high pressure processing". Food Microbiology 76 (2018): 416-425. https://doi.org/10.1016/j.fm.2018.07.002.
    10.1016/j.fm.2018.07.002
  23. Karabiyik, C.; Fernandes, R.; Figueiredo, F.R.; Socodato, R.; Brakebusch, C.; Lambertsen, K.L.; Relvas, J.B.; Santos, S.D.. "Neuronal Rho GTPase Rac1 elimination confers neuroprotection in a mouse model of permanent ischemic stroke". Brain Pathology 28 4 (2018): 569-580. http://www.scopus.com/inward/record.url?eid=2-s2.0-85050335924&partnerID=MN8TOARS.
    10.1111/bpa.12562
  24. Vilaça, N.; Totovao, R.; Prasetyanto, E.A.; Miranda-Gonçalves, V.; Morais-Santos, F.; Fernandes, R.; Figueiredo, F.; et al. "Internalization studies on zeolite nanoparticles using human cells". Journal of Materials Chemistry B 6 3 (2018): 469-476. http://www.scopus.com/inward/record.url?eid=2-s2.0-85040868389&partnerID=MN8TOARS.
    10.1039/c7tb02534c
  25. Anjo, S.I.; Figueiredo, F.; Fernandes, R.; Manadas, B.; Oliveira, M.. "A proteomic and ultrastructural characterization of Aspergillus fumigatus' conidia adaptation at different culture ages". Journal of Proteomics 161 (2017): 47-56. http://www.scopus.com/inward/record.url?eid=2-s2.0-85017103862&partnerID=MN8TOARS.
    10.1016/j.jprot.2017.03.021
  26. Aday, S.; Zoldan, J.; Besnier, M.; Carreto, L.; Saif, J.; Fernandes, R.; Santos, T.; et al. "Synthetic microparticles conjugated with VEGF165improve the survival of endothelial progenitor cells via microRNA-17 inhibition". Nature Communications 8 1 (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85030330994&partnerID=MN8TOARS.
    10.1038/s41467-017-00746-7
  27. Neves, A.R.; Queiroz, J.F.; Costa Lima, S.A.; Figueiredo, F.; Fernandes, R.; Reis, S.. "Cellular uptake and transcytosis of lipid-based nanoparticles across the intestinal barrier: Relevance for oral drug delivery". Journal of Colloid and Interface Science 463 (2016): 258-265. http://www.scopus.com/inward/record.url?eid=2-s2.0-84946600781&partnerID=MN8TOARS.
    10.1016/j.jcis.2015.10.057
  28. Pereira, C.L.; Teixeira, G.Q.; Ribeiro-Machado, C.; Caldeira, J.; Costa, M.; Figueiredo, F.; Fernandes, R.; et al. "Mesenchymal Stem/Stromal Cells seeded on cartilaginous endplates promote Intervertebral Disc Regeneration through Extracellular Matrix Remodeling". Scientific Reports 6 (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-84988672665&partnerID=MN8TOARS.
    10.1038/srep33836
  29. Pinheiro, A.M.; Carreira, A.; Rollo, F.; Fernandes, R.; Ferreira, R.B.; Monteiro, S.A.. "Blad-containing oligomer fungicidal activity on human pathogenic yeasts. From the outside to the inside of the target cell". Frontiers in Microbiology 7 NOV (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-85006725797&partnerID=MN8TOARS.
    10.3389/fmicb.2016.01803
  30. Inácio, Â.S.; Domingues, N.S.; Nunes, A.; Martins, P.T.; Moreno, M.J.; Estronca, L.M.; Fernandes, R.; et al. "Quaternary ammonium surfactant structure determines selective toxicity towards bacteria: Mechanisms of action and clinical implications in antibacterial prophylaxis". Journal of Antimicrobial Chemotherapy 71 3 (2016): 641-654. http://www.scopus.com/inward/record.url?eid=2-s2.0-84960839711&partnerID=MN8TOARS.
    10.1093/jac/dkv405
  31. Castro, C.; Couto, A.; Pérez-Jiménez, A.; Serra, C.R.; Díaz-Rosales, P.; Fernandes, R.; Corraze, G.; Panserat, S.; Oliva-Teles, A.. "Effects of fish oil replacement by vegetable oil blend on digestive enzymes and tissue histomorphology of European sea bass (Dicentrarchus labrax) juveniles". Fish Physiology and Biochemistry 42 1 (2016): 203-217. http://www.scopus.com/inward/record.url?eid=2-s2.0-84957435201&partnerID=MN8TOARS.
    10.1007/s10695-015-0130-1
  32. Mota, R.; Pereira, S.B.; Meazzini, M.; Fernandes, R.; Santos, A.; Evans, C.A.; De Philippis, R.; Wright, P.C.; Tamagnini, P.. "Differential proteomes of the cyanobacterium Cyanothece sp. CCY 0110 upon exposure to heavy metals". Data in Brief 4 (2015): 152-158. http://www.scopus.com/inward/record.url?eid=2-s2.0-84931259985&partnerID=MN8TOARS.
    10.1016/j.dib.2015.04.015
  33. Mota, R.; Pereira, S.B.; Meazzini, M.; Fernandes, R.; Santos, A.; Evans, C.A.; De Philippis, R.; Wright, P.C.; Tamagnini, P.. "Effects of heavy metals on Cyanothece sp. CCY 0110 growth, extracellular polymeric substances (EPS) production, ultrastructure and protein profiles". Journal of Proteomics 120 (2015): 75-94. http://www.scopus.com/inward/record.url?eid=2-s2.0-84924975714&partnerID=MN8TOARS.
    10.1016/j.jprot.2015.03.004
  34. Silva, A.; Sampaio, R.; Fernandes, R.; Pinto, E.. "Is there a role for adult non-cultivated bone marrow stem cells in ACL reconstruction?". Knee Surgery, Sports Traumatology, Arthroscopy 22 1 (2014): 66-71. http://www.scopus.com/inward/record.url?eid=2-s2.0-84891663643&partnerID=MN8TOARS.
    10.1007/s00167-012-2279-9
  35. Montani, L.; Buerki-Thurnherr, T.; de Faria, J.P.; Pereira, J.A.; Dias, N.G.; Fernandes, R.; Gonçalves, A.F.; et al. "Profilin 1 is required for peripheral nervous system myelination". Development (Cambridge) 141 7 (2014): 1553-1561. http://www.scopus.com/inward/record.url?eid=2-s2.0-84896286838&partnerID=MN8TOARS.
    10.1242/dev.101840
  36. Rocha, S.; Monjardino, P.; Mendonça, D.; Machado, A.C.; Fernandes, R.; Sampaio, P.; Salema, R.. "Lignification of developing maize (Zea mays L.) endosperm transfer cells and starchy endosperm cells". Frontiers in Plant Science 5 MAR (2014): http://www.scopus.com/inward/record.url?eid=2-s2.0-84901019138&partnerID=MN8TOARS.
    10.3389/fpls.2014.00102
  37. Sotiropoulos, I.; Lopes, A.T.; Pinto, V.; Lopes, S.; Carlos, S.; Duarte-Silva, S.; Neves-Carvalho, A.; et al. "Selective impact of Tau loss on nociceptive primary afferents and pain sensation". Experimental Neurology 261 (2014): 486-493. http://www.scopus.com/inward/record.url?eid=2-s2.0-84906070914&partnerID=MN8TOARS.
    10.1016/j.expneurol.2014.07.008
  38. Fundo, J.F.; Fernandes, R.; Almeida, P.M.; Carvalho, A.; Feio, G.; Silva, C.L.M.; Quintas, M.A.C.. "Molecular mobility, composition and structure analysis in glycerol plasticised chitosan films". Food Chemistry 144 (2014): 2-8. http://www.scopus.com/inward/record.url?eid=2-s2.0-84886420587&partnerID=MN8TOARS.
    10.1016/j.foodchem.2013.05.127
  39. Neto, E.; Alves, C.J.; Sousa, D.M.; Alencastre, I.S.; Lourenço, A.H.; Leitão, L.; Ryu, H.R.; et al. "Sensory neurons and osteoblasts: Close partners in a microfluidic platform". Integrative Biology (United Kingdom) 6 6 (2014): 586-595. http://www.scopus.com/inward/record.url?eid=2-s2.0-84901624359&partnerID=MN8TOARS.
    10.1039/c4ib00035h
  40. Arezes, J.; Costa, M.; Vieira, I.; Dias, V.; Kong, X.L.; Fernandes, R.; Vos, M.; et al. "Non-transferrin-bound iron (NTBI) uptake by T lymphocytes: Evidence for the selective acquisition of oligomeric ferric citrate species". PLoS ONE 8 11 (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84891893020&partnerID=MN8TOARS.
    10.1371/journal.pone.0079870
  41. Monjardino, P.; Rocha, S.; Tavares, A.C.; Fernandes, R.; Sampaio, P.; Salema, R.; da Câmara Machado, A.. "Development of flange and reticulate wall ingrowths in maize (Zea mays L.) endosperm transfer cells". Protoplasma 250 2 (2013): 495-503. http://www.scopus.com/inward/record.url?eid=2-s2.0-84875374602&partnerID=MN8TOARS.
    10.1007/s00709-012-0432-4
  42. Santos, S.D.; Fernandes, R.; Saraiva, M.J.. "The heat shock response modulates transthyretin deposition in the peripheral and autonomic nervous systems". Neurobiology of Aging 31 2 (2010): 280-289. http://www.scopus.com/inward/record.url?eid=2-s2.0-71349088766&partnerID=MN8TOARS.
    10.1016/j.neurobiolaging.2008.04.001
  43. Monjardino, P.; Machado, J.; Gil, F.S.; Fernandes, R.; Salema, R.. "Structural and ultrastructural characterization of maize coenocyte and endosperm cellularization". Canadian Journal of Botany 85 2 (2007): 216-223. http://www.scopus.com/inward/record.url?eid=2-s2.0-34250371772&partnerID=MN8TOARS.
    10.1139/B06-156
  44. Do Vale, A.; Costa-Ramos, C.; Silva, D.S.P.; Macedo, P.M.; Fernandes, R.; Sampaio, P.; Dos Santos, N.M.S.; Silva, M.T.. "Cytochemical and ultrastructural study of anoikis and secondary necrosis in enterocytes detached in vivo". Apoptosis 12 6 (2007): 1069-1083. http://www.scopus.com/inward/record.url?eid=2-s2.0-34247889986&partnerID=MN8TOARS.
    10.1007/s10495-006-0040-x
  45. Evangelista, M.B.; Hsiong, S.X.; Fernandes, R.; Sampaio, P.; Kong, H.-J.; Barrias, C.C.; Salema, R.; et al. "Upregulation of bone cell differentiation through immobilization within a synthetic extracellular matrix". Biomaterials 28 25 (2007): 3644-3655. http://www.scopus.com/inward/record.url?eid=2-s2.0-34249870130&partnerID=MN8TOARS.
    10.1016/j.biomaterials.2007.04.028
  46. Sousa, M.M.; Guimarães, A.; Fernandes, R.; do Amaral, J.B.; Saraiva, M.J.. "The molecular pathology of familial amyloid polyneuropathy | Patologia molecular associada à polineuropatia amiloidótica familiar". Sinapse 6 1 SUPPL. 1 (2006): 80-85. http://www.scopus.com/inward/record.url?eid=2-s2.0-33745357806&partnerID=MN8TOARS.
  47. Terazaki, H.; Ando, Y.; Fernandes, R.; Yamamura, K.-I.; Maeda, S.; Saraiva, M.J.. "Immunization in familial amyloidotic polyneuropathy: Counteracting deposition by immunization with a Y78F TTR mutant". Laboratory Investigation 86 1 (2006): 23-31. http://www.scopus.com/inward/record.url?eid=2-s2.0-32844473029&partnerID=MN8TOARS.
    10.1038/labinvest.3700365
  48. Saraiva, M.J.; Sousa, M.M.; Cardoso, I.; Fernandes, R.. "Familial amyloidotic polyneuropathy: Protein aggregation in the peripheral nervous system". Journal of Molecular Neuroscience 23 1-2 (2004): 35-40. http://www.scopus.com/inward/record.url?eid=2-s2.0-4344714361&partnerID=MN8TOARS.
  49. Concei¸ao, I.; Sales-Luis, M.L.; De Carvalho, M.; Evangelista, T.; Fernandes, R.; Paunio, T.; Kangas, H.; et al. "Gelsolin-related familial amyloidosis, finnish type, in a portuguese family: Clinical and neurophysiological studies". Muscle and Nerve 28 6 (2003): 715-721. http://www.scopus.com/inward/record.url?eid=2-s2.0-0344443397&partnerID=MN8TOARS.
    10.1002/mus.10474
  50. Sousa, M.M.; Fernandes, R.; Palha, J.A.; Taboada, A.; Vieira, P.; Saraiva, M.J.. "Evidence for early cytotoxic aggregates in transgenic mice for human transthyretin Leu55Pro". American Journal of Pathology 161 5 (2002): 1935-1948. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036841818&partnerID=MN8TOARS.
    10.1016/S0002-9440(10)64469-0
  51. Palha, J.A; Nissanov, J.; Fernandes, R.; Sousa, J.C.; Bertrand, L.; Dratman, M.B.; Morreale de Escobar, G.; Gottesman, M.; Saraiva, M.J.. "Thyroid hormone distribution in the mouse brain: The role of transthyretin". Neuroscience 113 4 (2002): 837-847. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037056057&partnerID=MN8TOARS.
    10.1016/S0306-4522(02)00228-2
  52. Mendes Sousa, M.M.; Cardoso, I.; Fernandes, R.; Guimarães, A.; João Saraiva, M.. "Deposition of transthyretin in early stages of familial amyloidotic polyneuropathy: Evidence for toxicity of nonfibrillar aggregates". American Journal of Pathology 159 6 (2001): 1993-2000. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035180285&partnerID=MN8TOARS.
    10.1016/S0002-9440(10)63050-7
  53. De Sousa, M.M.; Vital, C.; Ostler, D.; Fernandes, R.; Pouget-Abadie, J.; Carles, D.; Saraiva, M.J.. "Apolipoprotein AI and transthyretin as components of amyloid fibrils in a kindred with apoAI Leu178His amyloidosis". American Journal of Pathology 156 6 (2000): 1911-1917. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033898466&partnerID=MN8TOARS.
    10.1016/S0002-9440(10)65064-X
  54. Palha, J.A.; Fernandes, R.; De Escobar, G.M.; Episkopou, V.; Gottesman, M.; Saraiva, M.J.. "Transthyretin regulates thyroid hormone levels in the choroid plexus, but not in the brain parenchyma: Study in a transthyretin-null mouse model". Endocrinology 141 9 (2000): 3267-3272. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034458354&partnerID=MN8TOARS.
    10.1210/en.141.9.3267
  55. Palha, J.A.; Ballinari, D.; Amboldi, N.; Cardoso, I.; Fernandes, R.; Bellotti, V.; Merlini, G.; Saraiva, M.J.. "4'-iodo-4'-deoxydoxorubicin disrupts the fibrillar structure of transthyretin amyloid". American Journal of Pathology 156 6 (2000): 1919-1925. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033872046&partnerID=MN8TOARS.
    10.1016/S0002-9440(10)65065-1
  56. De Carvalho, M.; Moreira, P.; Evangelista, T.; Ducla-Soares, J.L.; Bento, M.; Fernandes, R.; Saraiva, M.J.. "New transthyretin mutation V28M in a Portuguese kindred with amyloid polyneuropathy". Muscle and Nerve 23 7 (2000): 1016-1021. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033933031&partnerID=MN8TOARS.
    10.1002/1097-4598(200007)23:7<1016::AID-MUS3>3.0.CO;2-W

Other

Other output
  1. The proteome of remyelination is different from that of developmental myelination. 2021. Joana Paes de Faria; Maria M. Azevedo; Damaris Bausch-Fluck; Ana Seixas; Helena S. Domingues; Maria A. Monteiro; Patrick G.A. Pedrioli; et al. https://doi.org/10.1101/2021.03.24.436006.
    10.1101/2021.03.24.436006
Activities

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2021/11 - 2021/11/12 V Technical Meeting of Electron Microscopy: Energy dispersive X-ray spectroscopy (EDS) analysis with SEM and TEM: How does it work? (2021/11/12 - 2021/11/12) (2021 - 2021)
Meeting (President of the Organising Committee)
 Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2022/09/24 - Current 4º Encontro Nacional de Jovens Investigadores em Oncologia
Meeting
2005 - Current School visits at I3S/IBMC School Visits - Education Program
Instituto de Biologia Molecular e Celular, Portugal
2007/06/18 - 2007/06/22 8th Advanced Course in Cell-Material Interactions - Inflammation in Tissue Repair and Regeneration. Porto
Seminar
 8th Advanced Course in Cell-Material Interactions – Inflammation in Tissue Repair and Regeneration.
Instituto Nacional de Engenharia Biomédica, Portugal
1997/05 - 1997/06 Course on "Molecular Neurogenetics" part of the Gulbenkian Graduate Programme (PGD)
Seminar
 Molecular Neurogenetics
Instituto de Biologia Molecular e Celular, Portugal
1996/07 - 1996/07 Course "Physiological and Molecular Aspects of Nitrogen and Hidrogen-Metabolism" - Gulbenkian Graduate Programme (PGDBM)
Seminar
Centro de Citologia Experimental da Universidade do Porto, Portugal

Association member

Society Organization name Role
2020 - Current SPMicros - Sociedade Portuguesa de Microscopia Vice-President
2014 - Current PPBI - Plataforma Portuguesa de Bioimagem

Committee member

Activity description
Role 		Institution / Organization
2018 - Current National Delegate on Management Committee of COST Action CA17121 _COMULIS - Correlated Multimodal Imaging in Life Sciences
Member

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2013 - Current Formação e Seminários Avançados Parte II / Histology and electron Microscopy Biologia Molecular e Celular (Doutoramento) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2012 - Current Técnicas Avançadas de Microscopia / Optical Microscopy and Bioimage Analysis mestrado em Biologia Celular e Molecular (Mestrado) Universidade do Porto Faculdade de Ciências, Portugal
2010 - 2019 Anatomia Patológica, Citológica e Tanatológica - monitorização de estágio de Microscopia Eletrónica Anatomia Patológica, Citológica e Tanatológica (Licenciatura) Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
2014 - 2018 Unidade curricular Técnicas Avançadas em Anatomia Patológica, Citológica e Tanatológica Anatomia Patológica, Citológica e Tanatológica (Licenciatura) Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
2013 - 2014 Estágio em Anatomia Patológica II - Módulo de Microscopia Eletrónica (Licenciatura) Instituto Politécnico de Lisboa Escola Superior de Tecnologia da Saúde de Lisboa, Portugal
2010 - 2013 4º ano de Anatomia Patológica, Citológica e Tanatológia da Escola Superior de Saúde do Vale do Sousa - CESPU_ Estágio de Aprendizagem Anatomia Patológica, Citológica e Tanatológica (Licenciatura) Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2011/10/17 - 2011/10/21 1st Course: Transmission Electron Microscopy: Theory, Techniques and Applications 1st Course: Transmission Electron Microscopy: Theory, Techniques and Applications (Diploma de especialização) Instituto de Biologia Molecular e Celular, Portugal
2010/02 - 2010/02 Laboratories of Transmission Electron Microscopy Ciência e Engenharia de Materiais (Doutoramento) Universidade de Aveiro Departamento de Engenharia de Materiais e Cerâmica, Portugal
Distinctions

Award

2003 Mention of Honour in the "Prémio BIAL 2002", from BIAL Foundation
Fundação Bial, Portugal