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MARTA SOFIA DE CARVALHO RIBEIRO VIANA PEREIRA. Concluiu o(a) Mestrado integrado em Mestrado Integrado em Medicina em 2019/07 pelo(a) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Doutoramento em Doutoramento em Ciências da Saúde em 2011/03 pelo(a) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde e Licenciatura em Biologia Aplicada em 2005/12 pelo(a) Universidade do Minho Departamento de Biologia. É Investigador visitante no(a) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde e Interno no(a) Hospital de Braga Oncologia Médica. Publicou 26 artigos em revistas especializadas. Possui 3 capítulo(s) de livros. Organizou 1 evento(s). Participou em 8 evento(s). Orientou 1 tese(s) de doutoramento. Orientou 7 dissertação(ões) de mestrado e coorientou 1. Orientou 6 trabalho(s) de conclusão de curso de licenciatura/bacharelato e coorientou 1. Recebeu 7 prémio(s) e/ou homenagens. Participa e/ou participou como Bolseiro de Doutoramento em 1 projeto(s), Bolseiro de Pós-Doutoramento em 3 projeto(s), Co-Investigador Responsável (Co-IR) em 1 projeto(s), Investigador em 3 projeto(s) e Investigador responsável em 2 projeto(s). Atua na(s) área(s) de Ciências Médicas e da Saúde com ênfase em Medicina Clínica com ênfase em Oncologia e Ciências Médicas e da Saúde com ênfase em Medicina Básica com ênfase em Patologia. No seu currículo Ciência Vitae os termos mais frequentes na contextualização da produção científica, tecnológica e artístico-cultural são: SPINT2; Biomarker; Melanoma; Targeted therapies; Homeoproteína HOXA9; Transcriptoma; Tumores Cerebrais; Prognóstico; .
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Identification

Personal identification

Full name
MARTA SOFIA DE CARVALHO RIBEIRO VIANA PEREIRA

Citation names

  • Viana-Pereira, Marta

Author identifiers

Ciência ID
9310-6B72-016A
ORCID iD
0000-0003-3087-0624

Addresses

  • Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho; ICVS/3B´s PT Government Associate Laboratory. Escola de Medicina, Universidade do Minho, Campus de Gualtar, 4710-057, Braga, Braga, Portugal (Professional)
  • Hospital de Braga, Serviço de Oncologia; Sete Fontes - São Victor , 4710-243, Braga, Braga, Portugal (Professional)

Knowledge fields

  • Medical and Health Sciences - Clinical Medicine - Oncology
  • Medical and Health Sciences - Basic Medicine - Pathology
Education
Degree Classification
2013/09 - 2019/07
Concluded
 Mestrado Integrado em Medicina (Mestrado integrado)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
"Study of the epigenetic silencing of the tumor suppressor gene SPINT2 in lung cancer" (THESIS/DISSERTATION)
 16
2007/01 - 2011/03
Concluded
 Doutoramento em Ciências da Saúde (Doutoramento)
Major in Ciências da Saúde
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
"Molecular Genetics of Paediatric versus Adult Brain Tumours" (THESIS/DISSERTATION)
2001/09 - 2005/12
Concluded
 Biologia Aplicada (Licenciatura)
Universidade do Minho Departamento de Biologia, Portugal
"The role of the PDZ protein PIST on zebrafish development" (THESIS/DISSERTATION)
 16
Affiliation

Science

Category
Host institution 		Employer
2021/12/11 - Current Visiting Researcher (Research) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2019/02 - 2021/12 Contracted Researcher (Research) Universidade do Minho Escola de Medicina, Portugal
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
(...)
2011/04 - 2019/02 Postdoc (Research) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
Laboratório Associado ICVS 3B's, Portugal
2008 - 2009 Visiting Researcher (Research) The Institute of Cancer Research, United Kingdom
The Institute of Cancer Research, United Kingdom
2006/01 - 2006/12 Researcher (Research) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal

Other Careers

Category
Host institution 		Employer
2021/01/01 - Current Interno (Médica) Hospital de Braga Oncologia Médica, Portugal
2020/01/01 - 2021/12/09 Interno (Médica) Hospital de Braga, Portugal
Hospital de Braga, Portugal
Projects

Grant

Designation Funders
2019/01/01 - 2019/12/31 Therapeutic relevance of the tumor suppressor gene SPINT2 in Melanoma
Bolsa LPCC/Fundação PT 2018
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
 Liga Portuguesa Contra o Cancro
Ongoing
2015 - 2019 Deciphering the tumorigenic role of the tumour suppressor gene SPINT2 in solid tumours
SFRH/BPD/104290/2014
Post-doc Fellow
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal

Laboratório Associado ICVS 3B's, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2013 - 2015 Integration of cutting-edge health science research and ground-breaking technologies for the development of new clinically useful therapies, tissue regeneration strategies, advanced prophylactic measures and diagnosis methods
N-01-01-01-24-01-07
Post-doc Fellow
Fundação para a Ciência e a Tecnologia
Concluded
2011 - 2013 Identification of novel target genes in microsatellite-unstable brain tumours
PTDC/SAU-ONC/115513/2009
Post-doc Fellow
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal

Laboratório Associado ICVS 3B's, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2007 - 2010 MOLECULAR GENETICS OF PAEDIATRIC VERSUS ADULT BRAIN TUMOURS
SFRH/BD/29145/2006
PhD Student Fellow
Laboratório Associado ICVS 3B's, Portugal

Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal

The Institute of Cancer Research, United Kingdom
Concluded

Contract

Designation Funders
2023/03/13 - Current WNTrack – Tracking brain tumors through their exosomes: a WNT6-driven approach
2022.05143.PTDC
Co-Principal Investigator (Co-PI)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal

Laboratório Associado ICVS 3B's, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2022/12/15 - Current A novel liquid biopsy tool for glioblastoma: a proof-of-concept - LiquidGBM
LiquidGBM
Researcher
Laboratório Associado ICVS 3B's, Portugal

Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
TecMinho Associação Universidade-Empresa para o Desenvolvimento
Ongoing
2011/04/01 - 2014/09/30 O Transcriptoma da Homeoproteína Oncogénica HOXA9 em Glioblastomas Humanos: Caracterização e Consequências Funcionais
PTDC/SAU-GMG/113795/2009
Universidade do Minho, Portugal

Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
Fundação para a Ciência e a Tecnologia
Concluded

Other

Designation Funders
2019/02 - Current Deciphering the tumorigenic role of the tumour suppressor gene SPINT2 in solid tumours
N/A
Principal investigator
Ongoing
Outputs

Publications

Book chapter
  1. Sónia Pires-Celeiro; Baltazar, F.; Viana-Pereira, Marta. "3D culture systems as models for solid tumors and cancer metabolism". In Biomaterials for 3D tumor modeling, edited by Kundu, Subhas; Reis, Rui L.. Elsevier, 2020.
    In press
  2. Viana-Pereira, Marta; Jones, Chris; Reis, Rui Manuel. "Pediatric High-Grade Glioma: Role of Microsatellite Instability". In Pediatric Cancer, Volume 3, 205-210. Springer Netherlands, 2012.
    Published • 10.1007/978-94-007-4528-5_22
  3. Viana-Pereira, Marta; Jones, Chris; Reis, Rui. "Genetic Instability in Paediatric and Adult Brain Tumours". In Molecular Targets of CNS Tumors, edited by Miklos Garami, 19-42. IntechOpen, 2011.
    10.5772/19571
Conference abstract
  1. Pereira, Márcia S.; Pinto, F.; Pardal, F.; Amorim, J.; Pires, M.; Pinheiro, C.; Lopes, J.M.; et al. "UNRAVELING THE BIOLOGICAL ROLE OF SPINT2 IN GLIOMAS". Paper presented in 46th Congress of the International Society of Paediatric Oncology (SIOP) - Pediatric Blood & Cancer, Toronto, 2014.
    Published • 10.1002/pbc.25314
  2. Viana-Pereira, Marta; Almeida, G.C.; Stavale, J.N.; Malheiro, S.; Pimentel, J.; Clara, C.; Reis, Rui Manuel. "STUDY OF TERT AND MECHANISTICALLY RELATED MOLECULES INMEDULLOBLASTOMAS". Paper presented in 46th Congress of the International Society of Paediatric Oncology (SIOP) - Pediatric Blood & Cancer, Toronto, 2014.
    Published • https://doi.org/10.1002/pbc.25314
  3. Almeida, M.; Portela, C.; Nabiço, R.; Ferreira, A.; Pardal, F.; Costa, Sandra; Ferreira, M.; et al. "Association of ESR1 Polymorphisms with Tamoxifen Response in Women with Estrogen Receptor-Positive Breast Cancer". Paper presented in IMPAKT Breast Cancer Conference - Annals of Oncology 24 (suppl 3), Bruxelas, 2013.
    Published • https://doi.org/10.1093/annonc/mdt083.11
  4. Gaspar, N.; Marshall, L.; Perryman, L.; Bax, D.A.; Little, S.E.; Viana-Pereira, Marta; Sharp, S.Y.; et al. "MGMT-Independent Temozolomide Resistance In Paediatric Glioblastoma Cells Associated With A PI3-Kinase-Mediated HOX / Stem Cell Gene Signature.". Paper presented in 14th International Symposium on Paediatric Neuro-Oncology (ISPNO 2010) - Neuro-Oncology 12(6), Viena, 2010.
    Published • 10.1093/neuonc/noq043
  5. Bax, D.A.; Mackay, A.; Little, S.E.; Carvalho, Diana; Viana-Pereira, Marta; Tamber, N.; Grigoriadis, A.E.; et al. "A Distinct Spectrum Of Copy Number Aberrations In Formalin-Fixed, Paraffin-Embedded Paediatric High Grade Glioma.". Paper presented in 14th International Symposium on Paediatric Neuro-Oncology (ISPNO 2010): Neuro-Oncology 12(6), Viena, 2010.
    Published • 10.1093/neuonc/noq043
  6. Viana-Pereira, Marta; Lee, A.; Popov, S.; Bax, D.A.; Al-Sarraj, S.; Bridges, L.R.; Stávale, J.N.; et al. "Microsatellite Instability in Pediatric High Grade Glioma is Associated with Genomic Profile and Differential Target Gene Inactivation.". Paper presented in 14th International Symposium on Paediatric Neuro-Oncology (ISPNO 2010): Neuro-Oncology 12(6), Viena, 2010.
    Published • 10.1093/neuonc/noq043
  7. Bax, D.A.; Marshall, L.; Gaspar, N.; Perryman, L.; Little, S.E.; Swansbury, J; Box, Gary; et al. "Molecular and phenotypic characterization of paediatric high grade glioma cell lines as models for preclinical drug development". Paper presented in 13th International Symposium on Pediatric Neuro-Oncology (ISPNO 2008): Neuro-oncology 10, Chicago, 2008.
    Published • 10.1215/15228517-2008-024
  8. Gaspar, N.; Marshall, L.; Bax, D.A.; Viana-Pereira, Marta; Little, S.E.; Perryman, L.; Pearson, A.D.J.; et al. "Differential mechanisms of Temozolomide resistance in paediatric glioma cell lines.". Paper presented in 13th International Symposium on Paediatric Neuro-Oncology (ISPNO 2008): Neuro-oncology 10, Chicago, 2008.
    Published • 10.1215/15228517-2008-024
  9. Viana-Pereira, Marta; Martinho, Olga; Lopes, J.M.; Mahler-Araújo, B.; Pimentel, J.; Reis, Rui Manuel. "Absence of KIT gene mutations and amplification in medulloblastomas.". Paper presented in 13th International Symposium on Paediatric Neuro-Oncology (ISPNO 2008): Neuro-oncology 10, Chicago, 2008.
    Published • 10.1215/15228517-2008-024
  10. Costa, B.M.; Pinheiro, C.; Costa, Sandra; Fernandes, R.; Viana-Pereira, Marta; Pardal, F.; Lopes, J.M.; Reis, Rui Manuel. "No Association between EGFR Promoter Gene Polymorphisms and Gliomas Risk.". Paper presented in VII congress of the European Association of Neuro-Oncology - Neuro-Oncology 8(4), Vienna, 2006.
    Published • 10.1215/15228517-2006-019
Conference poster
  1. Celeiro, Sónia Pires; reis rm; Baltazar, F.; Viana-Pereira, Marta. Corresponding author: Viana-Pereira, Marta. "SPINT2: a potential biomarker for melanoma patients". Paper presented in II ASPIC-ASEICA International Meeting - Current Trends in Precision Medicine in Cancer, 2021.
  2. Celeiro, Sónia Pires; Baltazar, F.; Reis, RM; Viana-Pereira, Marta. Corresponding author: Viana-Pereira, Marta. "SPINT2 downregulation in Melanoma influences EMT". Paper presented in EACR 2021 Virtual Congress, 2021.
  3. Celeiro, Sónia Pires; Reis, RM; Viana-Pereira, Marta. Corresponding author: Viana-Pereira, Marta. "SPINT2 role and therapeutic influence in Melanoma". Paper presented in Cancer biology: from basic to translational research, Liga Portuguesa Contra o Cancro, 2020.
  4. Sónia Pires-Celeiro; Reis, Rui Manuel; Viana-Pereira, Marta. "Therapeutic relevance of SPINT2 in Melanoma.". Paper presented in 6th International Society of Cancer Metabolism (ISCaM), 2019.
  5. Sónia Pires-Celeiro; Reis, Rui Manuel; Viana-Pereira, Marta. "Study of functional role and therapeutic influence of the tumor suppressor gene SPINT2 in Melanoma.". Paper presented in 25th Porto Cancer Meeting – Cancer Wars: The Immune Force Awakens, 2018.
  6. Márcia Pereira; Filipe Pinto; Lopes JM; Amorim, J.; Jones, C.; Viana-Pereira, Marta; Rui M. Reis. "Loss of SPINT2 is frequent in gliomas, leading to increases glioma cell growth and invasion, via a MMP2 activity". Paper presented in SNOLA-2018, 2018.
  7. Pereira, M.S.; Pinto, F.; Pardal, F.; Amorim, J.; Pires, M.M.; Pinheiro, C.; Lopes, J.M.; et al. "UNRAVELING THE BIOLOGICAL ROLE OF SPINT2 IN GLIOMAS". Paper presented in 46th Congress of the International Society of Paediatric Oncology (SIOP)., 2014.
  8. Viana-Pereira, Marta; Almeida, G.C.; Stavale, J.N.; Malheiro, S.; Pimentel, J.; Clara, C.; Reis, Rui Manuel. "STUDY OF TERT AND MECHANISTICALLY RELATED MOLECULES IN MEDULLOBLASTOMAS". Paper presented in 46th Congress of the International Society of Paediatric Oncology (SIOP)., 2014.
  9. Bidinotto LT; Mackay A; Viana-Pereira, Marta; Rui M. Reis. "Profile of genomic alterations of gliomas". Paper presented in XVI Jornada de Patologia do A.C.Camargo Cancer Center / VI Encontro Internacional de Patologia Investigativa, 2013.
  10. Couto E; Portela C; Almeida M; Nabiço R; Viana-Pereira, Marta; Rui M. Reis. "Association of SMAD7 single nucleotide polymorphisms with risk and prognosis of colorectal cancer in a Portuguese population". Paper presented in ESMO 15th World Congress on Gastrointestinal Cancer, 2013.
  11. Almeida M; Portela C; Nabiço R; Viana-Pereira, Marta; Rui M. Reis. "Association of esr1 polymorphisms with tamoxifen response in women with estrogen receptor-positive breast cancer". Paper presented in IMPAKT Breast Cancer Conference, 2013.
  12. Pereira MS; Viana-Pereira, Marta; Pinto F; Jones C; Rui M. Reis. "Epigenetic inactivation of SPINT2 in High Grade Gliomas". Paper presented in XXII Porto Cancer Meeting & III Porto-Bordeaux Joint Meeting - Translational Research in Cancer, 2013.
  13. Berardinelli GN; Scapulatempo-Neto C; Campanella, N.C.; Melani A; Viana-Pereira, Marta; Rui M. Reis. "Study of microsatellite instability (MSI) and mutations of MSI-target genes in large cohort of Brazilian colorectal cancer patients". Paper presented in Global Academic Program Meeting, 2013.
  14. Viana DV; Viana-Pereira, Marta; Almeida G; Jones C; Bertuzzo CS; Rui M. Reis. "Biallelic mutations in MMR gene in a retrospective series of CNS tumors". Paper presented in IV Annual IMPPC Conference/1st ICO-IDIBELL Hereditary Cancer Program Meeting. Hereditary and Familial Cancer In The Personal Genomics Era, 2013.
  15. Pereira MS; Viana-Pereira, Marta; Pinto F; Jones C; Rui M. Reis. "SPINT2 hypermethylation - a common event in high-grade gliomas". Paper presented in São Paulo School of Advanced Science (SPSAS) - Advances in Molecular Oncology: Translating Molecular Biology into Cancer Treatment, 2013.
  16. Viana-Pereira, Marta; Pereira MS; Burford A; Rui M. Reis; Jones C. "Molecular study and inhibition of MET receptor in paediatric high-grade glioma". Paper presented in São Paulo Advanced School of Comparative Oncology (ESPCA), 2012.
  17. Silva DS; Viana-Pereira, Marta; Jones C; Rui M. Reis. "Study of msi phenotype and novel target genes associated with msi phenotype in medulloblastomas". Paper presented in 15th International Symposium on Paediatric Neuro-Oncology (ISPNO 2012), 2012.
  18. Viana-Pereira, Marta; Pereira MS; Burford A; Rui M. Reis; Jones C. "Molecular determinants of efficacy of met receptor inhibition in paediatric glioblastoma.". Paper presented in 15th International Symposium on Paediatric Neuro-Oncology (ISPNO 2012), 2012.
  19. Viana-Pereira, Marta; Perryman L; Bax DA; Pereira MS; Rui M. Reis; Jones C. "MET receptor tyrosine kinase overexpression in paediatric malignant gliomas and in vitro response to tyrosine kinase inhibitor". Paper presented in EARC/FEBS advanced lecture course, Molecular Mechanisms in Signal Transduction and Cancer, 2011.
  20. Viana-Pereira, Marta. "Microsatellite Instability In High Grade Glioma". Paper presented in International Symposium on Clinical and Basic Investigation in Glioblastoma / II Symposium Fundación Seve Ballesteros, 2011.
  21. Viana-Pereira, Marta; Lee A; Hargrave D; Jones C; Rui M. Reis. "Novel genetic Instability in Paediatric High Grade Glioma". Paper presented in XX Porto Cancer Meeting “Drug Resistance in Cancer: from biology to molecular targets and drugs, 2011.
  22. Costa BM; Viana-Pereira, Marta; Fernandes R.; Rui M Reis. "Associations between functional EGFR -216G/T, -191C/A, and Intron 1 (CA)n Repeat polymorphisms and glioma risk". Paper presented in 21st Meeting of the EA European Association for Cancer Research, 2010.
  23. Viana-Pereira, Marta; Bax, D.A.; Almeida, I.; Sousa, S.; Popov, S.; Mahler-Araújo, B.; Seruca, Raquel; et al. "Microsatellite instability in paediatric high grade glioma and medulloblastoma". Paper presented in Institute of Cancer Research Centenary Conference, 2009.
  24. Bax, D.A.; Little, S.E.; Gaspar, N.; Perryman, L.; Marshall, L.; Viana-Pereira, Marta; Jones, T.A.; et al. "Molecular and phenotypic characterization of paediatric glioma cell lines as model for preclinical drug development.". Paper presented in Institute of Cancer Research Centenary Conference, 2009.
  25. Gaspar N; Bax DA; Marshall L; Viana-Pereira, Marta; Little SE; Rui M.Reis; Hargrave D; Jones C. "MGMT-independent resistance to temozolomide associated with a HOX/stem cell gene signature in paediatric glioblastoma cells". Paper presented in Institute of Cancer Research Centenary Conference, 2009.
  26. Bax DA; Gaspar N; Little SE; Viana-Pereira, Marta; Reis-Filho, J.S.; Rui M. Reis; Hargrave D; Workman, P; Jones C. "EGFRvIII deletion mutations in paediatric high grade glioma and response to targeted therapy in paediatric glioma cell lines". Paper presented in Institute of Cancer Research Centenary Conference, 2009.
  27. Viana-Pereira, Marta; Almeida, I.; Sousa, S.; Mahler-Araújo, B.; Seruca, Raquel; Pimentel, J.; Reis, Rui Manuel. "Microsatellite instability: A new type of genetic instability in medulloblastomas?". Paper presented in AACR Annual Meeting 2009, 2009.
  28. Gaspar N; Marshall L; Bax DA; Viana-Pereira, Marta; Little SE; Rui M. Reis; Jones C. "Differential mechanisms of Temozolomide resistance in paediatric glioma cell lines". Paper presented in 13th International Symposium on Paediatric Neuro-Oncology (ISPNO 2008), 2008.
  29. Viana-Pereira, Marta; Martinho O; Lopes JM; Mahler-Araújo, B.; Pimentel JG; Rui M. Reis. "Absence of KIT gene mutations and amplification in medulloblastomas.". Paper presented in 13th International Symposium on Paediatric Neuro-Oncology (ISPNO 2008), 2008.
  30. Viana-Pereira, Marta; Martinho O; Lopes JM; Pimentel JG; Rui M. Reis. "Study of KIT Oncogene in Medulloblastomas". Paper presented in 10th Cancer Research UK Beatson International Cancer Conference: Molecular Cancer Therapies: New Challenges and Horizons, 2007.
  31. Costa BM; Pinheiro C; Viana-Pereira, Marta; Rui M. Reis. "No Association between EGFR Promoter Gene Polymorphisms and Gliomas Risk". Paper presented in VII congress of the European Association of Neuro-Oncology, 2006.
  32. Viana-Pereira, Marta; Pinheiro C; Bento I; Rui M. Reis. "Association of EGFR Intron 1 CA Repeat with Glioma Risk". Paper presented in 10th Meeting of Portuguese Society of Human Genetics, 2006.
Journal article
  1. Peixoto M; Viana-Pereira M; Amorim MJ; Marques AD; Freitas D; Cunha J; Pereira F; Reis R; Couto E. "Impact of Suppressor of Mothers Against Decapentaplegic (SMAD) 7 Gene Single Nucleotide Polymorphisms on Colorectal Cancer Risk and Prognosis.". Cureus (2024): https://europepmc.org/articles/PMC11500270.
    10.7759/cureus.70081
  2. Araújo, Inês M; Robalo, Margarida; Domingues, Rui; Viana Pereira, Marta; Esperança, Sofia. "Seronegative Celiac Disease - A Challenging Case". Cureus (2022): http://dx.doi.org/10.7759/cureus.27730.
    10.7759/cureus.27730
  3. Robalo, Maria Margarida; Araújo, Inês M; Domingues, Rui M; Viana Pereira, Marta; Esperança, Sofia. "Heart Failure: From Typical Clinical Manifestations to the Surprising Final Diagnosis". Cureus (2022): http://dx.doi.org/10.7759/cureus.26870.
    10.7759/cureus.26870
  4. Oliveira, Rafaela Dias; Celeiro, Sónia Pires; Barbosa-Matos, Catarina; Freitas, Ana Sofia; Cardoso, Susana M.; Viana-Pereira, Marta; Almeida-Aguiar, Cristina; Baltazar, Fátima. "Portuguese Propolis Antitumoral Activity in Melanoma Involves ROS Production and Induction of Apoptosis". Molecules 27 11 (2022): 3533. http://dx.doi.org/10.3390/molecules27113533.
    10.3390/molecules27113533
  5. Nshizirungu, Jean Paul; Bennis, Sanae; Mellouki, Ihsane; Sekal, Mohammed; Benajah, Dafr-Allah; Lahmidani, Nada; El Bouhaddouti, Hicham; et al. "Reproduction of the Cancer Genome Atlas (TCGA) and Asian Cancer Research Group (ACRG) Gastric Cancer Molecular Classifications and Their Association with Clinicopathological Characteristics and Overall Survival in Moroccan Patients". Disease Markers 2021 (2021): 1-12. http://dx.doi.org/10.1155/2021/9980410.
    Open access • 10.1155/2021/9980410
  6. Nshizirungu, Jean Paul; Bennis, Sanae; Mellouki, Ihsane; Benajah, Dafr-Allah; Lahmidani, Nada; El Bouhaddoutti, Hicham; Ibn Majdoub, Karim; et al. "Microsatellite Instability Analysis in Gastric Carcinomas of Moroccan Patients". Genetic Testing and Molecular Biomarkers 25 2 (2021): 116-123. http://dx.doi.org/10.1089/gtmb.2020.0146.
    10.1089/gtmb.2020.0146
  7. Pereira, Marta. "Loss of SPINT2 expression frequently occurs in glioma, leading to increased growth and invasion via MMP2.". Cellular Oncology (2020): https://doi.org/10.1007/s13402-019-00475-7.
    10.1007/s13402-019-00475-7
  8. Marta Viana-Pereira; Daniel Antunes Moreno; Paulo Linhares; Júlia Amorim; Rui Nabiço; Sandra Costa; Rui Vaz; Rui Manuel Reis. "Replication of GWAS identifies RTEL1, CDKN2A/B, and PHLDB1 SNPs as risk factors in Portuguese gliomas patients". Molecular Biology Reports 47 2 (2020): 877-886. https://doi.org/10.1007/s11033-019-05178-8.
    10.1007/s11033-019-05178-8
  9. Pereira, Marta. "Genetic variants of vascular endothelial growth factor predict risk and survival of gliomas". Tumor Biology 40 3 (2018): https://www.scopus.com/inward/record.uri?eid=2-s2.0-85044680028&doi=10.1177%2f1010428318766273&partnerID=40&md5=90a65746a59303f8fdfb0b36e8678713.
    10.1177/1010428318766273
  10. Xavier-Magalhães, A.; Oliveira, A.I.; de Castro, J.V.; Pojo, M.; Gonçalves, C.S.; Lourenço, T.; Viana-Pereira, M.; et al. "Effects of the functional HOTAIR rs920778 and rs12826786 genetic variants in glioma susceptibility and patient prognosis". Journal of Neuro-Oncology 132 1 (2017): 27-34. http://www.scopus.com/inward/record.url?eid=2-s2.0-85009278934&partnerID=MN8TOARS.
    10.1007/s11060-016-2345-0
  11. Viana-Pereira, M.; Almeida, G.C.; Stavale, J.N.; Malheiro, S.; Clara, C.; Lobo, P.; Pimentel, J.; Reis, R.M.. "Study of hTERT and Histone 3 Mutations in Medulloblastoma". Pathobiology 84 2 (2017): 108-113. http://www.scopus.com/inward/record.url?eid=2-s2.0-84990215059&partnerID=MN8TOARS.
    10.1159/000448922
  12. Batista, R.; Cruvinel-Carloni, A.; Vinagre, J.; Peixoto, J.; Catarino, T.A.; Campanella, N.C.; Menezes, W.; et al. "The prognostic impact of TERT promoter mutations in glioblastomas is modified by the rs2853669 single nucleotide polymorphism". International Journal of Cancer 139 2 (2016): 414-423. http://www.scopus.com/inward/record.url?eid=2-s2.0-84961644849&partnerID=MN8TOARS.
    10.1002/ijc.30057
  13. Bidinotto, L.T.; Torrieri, R.; Mackay, A.; Almeida, G.C.; Viana-Pereira, M.; Cruvinel-Carloni, A.; Spina, M.L.; et al. "Copy number profiling of Brazilian astrocytomas". G3: Genes, Genomes, Genetics 6 7 (2016): 1867-1878. http://www.scopus.com/inward/record.url?eid=2-s2.0-84978394351&partnerID=MN8TOARS.
    10.1534/g3.116.029884
  14. Martins, S.F.; Amorim, R.; Viana-Pereira, M.; Pinheiro, C.; Costa, R.F.A.; Silva, P.; Couto, C.; et al. "Significance of glycolytic metabolism-related protein expression in colorectal cancer, lymph node and hepatic metastasis". BMC Cancer 16 1 (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-84979211096&partnerID=MN8TOARS.
    10.1186/s12885-016-2566-9
  15. Pereira, M.S.; de Almeida, G.C.; Pinto, F.; Viana-Pereira, M.; Reis, R.M.. "SPINT2 Deregulation in Prostate Carcinoma". Journal of Histochemistry and Cytochemistry 64 1 (2016): 32-41. http://www.scopus.com/inward/record.url?eid=2-s2.0-84952901065&partnerID=MN8TOARS.
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    10.1007/s13277-015-3343-0
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    10.1371/journal.pone.0137690
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    10.4161/onci.28609
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    10.1371/journal.pone.0020588
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Activities

Oral presentation

Presentation title Event name
Host (Event location)
2020/09/09 Therapeutic relevance of the tumor suppressor gene SPINT2 in Melanoma Seminar Series
IINFACTS, CESPU (Paredes, Portugal)
2011/06/23 Microsatellite Instability In High Grade Glioma International Symposium on Clinical and Basic Investigation in Glioblastoma / II Symposium Fundación Seve Ballesteros
Fundación Seve Ballesteros (Valencia, Spain)
2010/06/22 MGMT-Independent Temozolomide Resistance In Paediatric Glioblastoma Cells Associated With A PI3-Kinase-Mediated HOX / Stem Cell Gene Signature 14th International Symposium on Paediatric Neuro-Oncology (ISPNO 2010)
Paediatric Neuro-Oncology Society (Viena, Austria)
2010/06/20 A Distinct Spectrum Of Copy Number Aberrations In Formalin-Fixed, Paraffin-Embedded Paediatric High Grade Glioma. 14th International Symposium on Paediatric Neuro-Oncology (ISPNO 2010)
Paediatric Neuro-Oncology society (Vienna, Austria)
2010/06/20 Microsatellite Instability in Pediatric High Grade Glioma is Associated with Genomic Profile and Differential Target Gene Inactivation. 14th International Symposium on Paediatric Neuro-Oncology (ISPNO 2010)
Paediatric Neuro-Oncology Society (Vienna, Austria)
2010/06/01 Microsatellite Instability in Pediatric High Grade Glioma is Associated with Genomic Profile and Differential Target Gene Inactivation XXXV Portuguese Genetics Conference
Portuguese Genetics Society (Braga)
2008/10/24 Presence of microsatellite instability in Medulloblastoma 1st National Congress of the Portuguese Society of Neuro-Oncology
Associação Portuguesa de Neuro-Oncologia (Vilamoura)
2008/06/29 Molecular and phenotypic characterization of paediatric high grade glioma cell lines as models for preclinical drug development. 13th International Symposium on Paediatric Neuro-Oncology (ISPNO 2008)
Paediatric Neuro-Oncology Society (Chicago, United States)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2021/01/01 - Current Deciphering the role of the serine protease inhibitor SPINT2 managing melanoma tumorigenesis and therapeutic response
Supervisor of Sónia Pires Celeiro
 PhD in Health Sciences (PhD)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal

Laboratório Associado ICVS 3B's, Portugal
2018 - 2019 ESR1 Polymorphisms Association with Survival in Women with Breast Cancer Treated with Tamoxifen
Supervisor
 Medical degree (Master)
Universidade do Minho Escola de Medicina, Portugal
2018 - 2019 Therapeutic relevance of the tumor suppressor gene SPINT2 in Melanoma
Supervisor
 Fellow financed by Liga Portuguesa Contra o Cancro to Sónia Pires Celeiro (Other)
Liga Portuguesa Contra o Cancro, Portugal

Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2017 - 2018 SPINT2 expression in lung cancer
Supervisor
 Medical degree (Master)
Universidade do Minho Escola de Medicina, Portugal
2017 - 2018 Study of functional role and therapeutic influence of the tumor suppressor gene SPINT2 in Melanoma
Supervisor
 Master degree in health sciences (Master)
Universidade do Minho Escola de Medicina, Portugal
2014 - 2015 THE TUMOR SUPRESSOR GENE SPINT2 IS A NOVEL PROGNOSTIC FACTOR IN MELANOMA
Supervisor
 Biochemistry (Degree)
Universidade do Minho Escola de Ciências, Portugal
2014 - 2015 Establishing a in vitro 3D tumor culture model
Supervisor
 Biochemistry (Degree)
Universidade do Minho Escola de Ciências, Portugal
2014 - 2015 Epigenetic Silencing of SPINT2 in Colorectal Cancer: Study of Gene Promoter Methylation on Lymph Node Metastasis
Supervisor
 Medical Degree (Master)
Universidade do Minho Escola de Medicina, Portugal
2013 - 2014 The role of SPINT2 on cellular invasion in gliomas
Supervisor
 Biochemistry (Degree)
Universidade do Minho Escola de Ciências, Portugal
2013 - 2014 Establishing a 3D tumor model
Supervisor
 Biochemistry (Degree)
Universidade do Minho Escola de Ciências, Portugal
2013 - 2014 Characterization of Microsatellite Instability in Colorectal Patients With Surgical Treatment
Supervisor
 Medical Degree (Master)
Universidade do Minho Escola de Medicina, Portugal
2013 - 2014 Expression of SPINT2 Protein in Lymph Node Metastasis of Colorectal Cancer
Supervisor
 Medical Degree (Master)
Universidade do Minho Escola de Medicina, Portugal
2012 - 2013 The role of SPINT2 in Colorectal Cancer: Evaluation of SPINT2 gene methylation and immunohistochemical protein expression
Co-supervisor
 Medical degree (Master)
Universidade do Minho Escola de Medicina, Portugal
2012 - 2013 Study of MET overexpression and BRAF / KRAS mutations in colorectal cancer
Supervisor
 Biochemistry (Degree)
Universidade do Minho Escola de Ciências, Portugal
2012 - 2013 UNRAVELING THE BIOLOGICAL ROLE OF SPINT2 IN GLIOMAS
Supervisor
 Master in Health Sciences (Master)
Universidade do Minho Escola de Medicina, Portugal
2010 - 2011 Study of SPINT2 Methylation in Central Nervous System Tumors
Supervisor
 Biochemistry (Degree)
Universidade do Minho Escola de Medicina, Portugal
2009 - 2010 Co-supervision of a curricular internship of a last year student of Biochemistry, School of Sciences, University of Minho
Co-supervisor
 Biochemistry (Degree)
Universidade do Minho Escola de Ciências, Portugal

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2019/11/08 - 2019/11/08 ASPIC CONFERENCE: Paediatric Cancer Research: Where are we? What is in the future? (2019/11/08 - 2019/11/08)
Congress (Member of the Organising Committee)
 Fundação Calouste Gulbenkian, Portugal

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2023/03/16 - Current Palestrante do Workshop "Abordagem do doente oncológico em MGF"
Meeting
 1º Encontro de Medicina Geral e Familiar de Braga
2007 - Current Participation in several activities of scientific divulgation for students from primary school to high school, such as “ABC da Cirurgia”; “Verão no Campus”; “Semana da Ciência e Tecnologia” since 2007
Other
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal

Laboratório Associado ICVS 3B's, Portugal
2009/05/13 - 2009/05/24 Learning and Development: Statistics for Students and Researchers Learning and Development: Statistics for Students and Researchers
The Institute of Cancer Research, United Kingdom
2009/02/26 - 2009/02/27 Learning and Development: Improving your Presentation Skills Learning and Development: Improving your Presentation Skills
The Institute of Cancer Research, United Kingdom
2008/10/17 - 2008/10/17 Learning and Development: Effective Writing for Students Learning and Development: Effective Writing for Students
The Institute of Cancer Research, United Kingdom

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2018/10/23 Study of functional role and therapeutic influence of the tumor suppressor gene SPINT2 in Melanoma
Supervisor
 Sónia Pires Celeiro (Master)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal

Universidade do Minho Escola de Medicina, Portugal
2016/10/27 Researching novel proteins involved in aneuploidy
(Thesis) Main arguer
 Raquel Soares Pereira (Master)
Universidade do Minho Escola de Ciências, Portugal
2013/12/11 UNRAVELING THE BIOLOGICAL ROLE OF SPINT2 IN GLIOMAS
Supervisor
 Ma´rcia Micaela Santos Pereira (Master)
Universidade do Minho Escola de Medicina, Portugal

Laboratório Associado ICVS 3B's, Portugal

Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal

Association member

Society Organization name Role
2021 - Current Sociedade Portuguesa de Oncologia Member
2019/08/21 - Current Ordem dos Médicos Membro da Ordem
2012 - Current European Association of Neuro-Oncology Member
2009 - Current American Association for Cancer Research (AACR) Member
2007 - Current European Association for Cancer Research (EACR) Member

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2021/04 - Current workshop “Development of 3D culture systems for in vitro study of tumour pathophysiology”, in III Jornadas da Ciência (Licenciatura) Universidade do Minho Departamento de Biologia, Portugal
2019/09 - Current Member of the Teaching Staff of Fundamentals of Genetics, Development and Neoplasia (Pós-Graduação) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2016 - 2017 Fundamentals of Genetics, Development and Neoplasia- Member of the teaching staff of this post-graduation course Fundamentals of Genetics, Development and Neoplasia (Pós-Graduação) Universidade do Minho Escola de Medicina, Portugal
2015 - 2016 “Fundamentals of Genetics, Development and Neoplasia”- Member of the teaching staff of this post-graduation course “Fundamentals of Genetics, Development and Neoplasia” (Pós-Graduação) Universidade do Minho Escola de Medicina, Portugal
2015 - 2016 “Epigenetics - from mechanisms to disease” - Member of the teaching staff of this post-graduation course Epigenetics - from mechanisms to disease (Pós-Graduação) Universidade do Minho Escola de Medicina, Portugal
2013 - 2014 Member of the teaching staff of the PhD program “Neurosciences” Neurosciences (Curso de doutoramento (conclusão de unidades curriculares)) Universidade do Porto Faculdade de Medicina, Portugal
2013 - 2014 Member of the teaching staff of the post-graduation course “Fundamentals in Neurosciences” Fundamentals in Neurosciences (Pós-Graduação) Universidade do Minho Escola de Medicina, Portugal
2013 - 2014 Member of the teaching staff of the post-graduation course “Fundamentals of Genetics, Development and Neoplasia” Fundamentals of Genetics, Development and Neoplasia (Pós-Graduação) Universidade do Minho Escola de Medicina, Portugal
2012 - 2013 Member of the teaching staff of the post-graduation course “Fundamentals of Genetics, Development and Neoplasia” Fundamentals of Genetics, Development and Neoplasia (Pós-Graduação) Universidade do Minho Escola de Medicina, Portugal
2011 - 2012 Invited lecturer to the seminar “Cell signaling: Receptor Tyrosine Kinases” in the post-graduation course “Fundamentals of Genetics, Development and Neoplasia” Fundamentals of Genetics, Development and Neoplasia (Pós-Graduação) Universidade do Minho Escola de Medicina, Portugal
2010 - 2011 "Translational research in paediatrics"_Invited lecturer in a seminar from the curricular field “From clinics to Molecular Biology III” Medicina (Mestrado integrado) Universidade do Minho Escola de Medicina, Portugal
Distinctions

Award

2018 Research Fellowship - LPCC/Fundação PT 2018
Liga Portuguesa Contra o Cancro, Portugal

Other distinction

2013 Travel Fellowship Award
2011 Best poster Prize for the Translational Research Session, XX Porto Cancer Meeting “Drug Resistance in Cancer: from biology to molecular targets and drugs”
2007 Treaty of Windsor Anglo-Portuguese Joint Research Programme (2008/2009): Study of Molecular Targets for Paediatric Brain Tumours Therap