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Identification

Personal identification

Full name
Maria João Araújo

Citation names

  • Araújo, Maria

Author identifiers

Ciência ID
9411-5B54-354A
ORCID iD
0000-0002-3106-4205
Education
Degree Classification
1995
Concluded
 Química (Doutoramento)
Major in Outra:Química Orgânica
Universidade do Porto Faculdade de Ciências, Portugal
"Estudo de Síntese em Poliaminas" (THESIS/DISSERTATION)
Affiliation

Teaching in Higher Education

Category
Host institution 		Employer
2016 - 2023 Assistant Professor (University Teacher) Universidade do Porto, Portugal
2016 - 2019 Assistant Professor (University Teacher) Universidade do Porto, Portugal
2013 - 2016 Assistant Professor (University Teacher) Universidade do Porto Faculdade de Ciências, Portugal
1995/07/17 - 2016 Assistant Professor (University Teacher) Universidade do Porto Faculdade de Ciências, Portugal
Projects

Grant

Designation Funders
2023/02/13 - 2025/03/31 KIWIBOL - KIWIBOL - Investigar para além do complexo da ESCA do kiwi para validar uma estratégia peptídica para o controlo da doença
PTDC/ASP-PLA/2440/2021
Principal investigator
REQUIMTE LAQV Porto, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing

Contract

Designation Funders
2011/01/01 - 2014/06/30 Uma nova abordagem à veiculação de fármacos: lipossomas cataniónicos e nanotubos baseados em derivados de aminoácidos
PTDC/QUI-QUI/115212/2009
Universidade do Porto Centro de Investigação em Química, Portugal

Universidade do Porto Faculdade de Ciências, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Journal article
  1. Isabel S. Oliveira; Rui L. Machado; Maria J. Araújo; Andreia C. Gomes; Eduardo F. Marques. "Stimuli-Sensitive Self-Assembled Tubules Based on Lysine-Derived Surfactants for Delivery of Antimicrobial Proteins". Chemistry – A European Journal (2021): https://doi.org/10.1002/chem.202003320.
    10.1002/chem.202003320
  2. "4,9-diaminoacridines and 4-aminoacridines as dual-stage antiplasmodial hits". ChemMedChem (2020): http://dx.doi.org/10.1002/cmdc.202000740.
    10.1002/cmdc.202000740
  3. "Biocompatible thermosensitive nanostructures and hydrogels of an amino acid-derived surfactant and hydroxyethyl cellulose polymers". Journal of Molecular Liquids (2020): http://dx.doi.org/10.1016/j.molliq.2020.114540.
    10.1016/j.molliq.2020.114540
  4. Oliveira, I.S.; Lo, M.; Araújo, M.J.; Marques, E.F.. "Temperature-responsive self-assembled nanostructures from lysine-based surfactants with high chain length asymmetry: From tubules and helical ribbons to micelles and vesicles". Soft Matter 15 18 (2019): 3700-3711. http://www.scopus.com/inward/record.url?eid=2-s2.0-85065472919&partnerID=MN8TOARS.
    10.1039/c9sm00399a
  5. Costa, M.; Sampaio-Dias, I.E.; Castelo-Branco, R.; Scharfenstein, H.; Rezende De Castro, R.; Silva, A.; Schneider, M.P.C.; et al. "Structure of hierridin c, synthesis of hierridins b and c, and evidence for prevalent alkylresorcinol biosynthesis in picocyanobacteria". Journal of Natural Products 82 2 (2019): 393-402. http://www.scopus.com/inward/record.url?eid=2-s2.0-85061266922&partnerID=MN8TOARS.
    10.1021/acs.jnatprod.8b01038
  6. Fonte, M.; Fagundes, N.; Gomes, A.; Ferraz, R.; Prudêncio, C.; Araújo, M.J.; Gomes, P.; Teixeira, C.. "Development of a synthetic route towards N 4 ,N 9 -disubstituted 4,9-diaminoacridines: On the way to multi-stage antimalarials". Tetrahedron Letters 60 17 (2019): 1166-1169. http://www.scopus.com/inward/record.url?eid=2-s2.0-85063271551&partnerID=MN8TOARS.
    10.1016/j.tetlet.2019.03.052
  7. Vale, N.; Ferreira, A.; Fernandes, I.; Alves, C.; Araújo, M.J.; Mateus, N.; Gomes, P.. "Gemcitabine anti-proliferative activity significantly enhanced upon conjugation with cell-penetrating peptides". Bioorganic and Medicinal Chemistry Letters 27 13 (2017): 2898-2901. http://www.scopus.com/inward/record.url?eid=2-s2.0-85019023221&partnerID=MN8TOARS.
    10.1016/j.bmcl.2017.04.086
  8. "11th National Meeting of Organic Chemistry and 4th Meeting of Therapeutic Chemistry". Pharmaceuticals (2016): http://www.mdpi.com/1424-8247/9/1/15.
    10.3390/ph9010015
  9. Ornelas, M.; Azenha, M.; Araújo, M.J.; Marques, E.F.; Dias-Cabral, A.C.; Pereira, C.; Silva, A.F.. "Acylated-naproxen as the surface-active template in the preparation of micro- and nanospherical imprinted xerogels by emulsion techniques". Journal of Chromatography A 1437 (2016): 107-115. http://www.scopus.com/inward/record.url?eid=2-s2.0-84983122401&partnerID=MN8TOARS.
    10.1016/j.chroma.2016.01.074
  10. Teixeira, R.S.; Cova, T.F.G.G.; Silva, S.M.C.; Oliveira, R.; Araújo, M.J.; Marques, E.F.; Pais, A.A.C.C.; Veiga, F.J.B.. "Erratum: Lysine-based surfactants as chemical permeation enhancers for dermal delivery of local anesthetics (International Journal of Pharmaceutics (2014) 474 (212-222))". International Journal of Pharmaceutics 475 1 (2014): http://www.scopus.com/inward/record.url?eid=2-s2.0-84908202684&partnerID=MN8TOARS.
    10.1016/j.ijpharm.2014.10.001
  11. Teixeira, R.S.; Cova, T.F.G.G.; Silva, S.M.C.; Oliveira, R.; Araújo, M.J.; Marques, E.F.; Pais, A.A.C.C.; Veiga, F.J.B.. "Lysine-based surfactants as chemical permeation enhancers for dermal delivery of local anesthetics". International Journal of Pharmaceutics 474 1-2 (2014): 212-222. http://www.scopus.com/inward/record.url?eid=2-s2.0-84906666979&partnerID=MN8TOARS.
    10.1016/j.ijpharm.2014.08.002
  12. Calejo, M.T.; Cardoso, A.M.S.; Marques, E.F.; Araújo, M.J.; Kjøniksen, A.-L.; Sande, S.A.; de Lima, M.C.P.; Jurado, A.S.; Nyström, B.. "In vitro cytotoxicity of a thermoresponsive gel system combining ethyl(hydroxyethyl) cellulose and lysine-based surfactants". Colloids and Surfaces B: Biointerfaces 102 (2013): 682-686. http://www.scopus.com/inward/record.url?eid=2-s2.0-84867835593&partnerID=MN8TOARS.
    10.1016/j.colsurfb.2012.09.033
  13. Brito, R.O.; Oliveira, I.S.; Araújo, M.J.; Marques, E.F.. "Morphology, thermal behavior, and stability of self-assembled supramolecular tubules from lysine-based surfactants". Journal of Physical Chemistry B 117 32 (2013): 9400-9411. http://www.scopus.com/inward/record.url?eid=2-s2.0-84882328101&partnerID=MN8TOARS.
    10.1021/jp400127k
  14. Ornelas, M.; Loureiro, D.; Araújo, M.J.; Marques, E.; Dias-Cabral, C.; Azenha, M.; Silva, F.. "Synthesis of glycylglycine-imprinted silica microspheres through different water-in-oil emulsion techniques". Journal of Chromatography A 1297 (2013): 138-145. http://www.scopus.com/inward/record.url?eid=2-s2.0-84878947120&partnerID=MN8TOARS.
    10.1016/j.chroma.2013.04.077
  15. Calejo, M.T.; Kjoniksen, A.-L.; Marques, E.F.; Araújo, M.J.; Sande, S.A.; Nyström, B.. "Interactions between ethyl(hydroxyethyl) cellulose and lysine-based surfactants in aqueous media". European Polymer Journal 48 9 (2012): 1622-1631. http://www.scopus.com/inward/record.url?eid=2-s2.0-84864780629&partnerID=MN8TOARS.
    10.1016/j.eurpolymj.2012.06.009
  16. Brito, R.O.; Marques, E.F.; Silva, S.G.; do Vale, M.L.; Gomes, P.; Araújo, M.J.; Rodriguez-Borges, J.E.; et al. "Physicochemical and toxicological properties of novel amino acid-based amphiphiles and their spontaneously formed catanionic vesicles". Colloids and Surfaces B: Biointerfaces 72 1 (2009): 80-87. http://www.scopus.com/inward/record.url?eid=2-s2.0-67349083234&partnerID=MN8TOARS.
    10.1016/j.colsurfb.2009.03.017
  17. Marques, E.F.; Brito, R.O.; Silva, S.G.; Enrique Rodríguez-Borges, J.; Vale, M.L.D.; Gomes, P.; Araújo, M.J.; Söderman, O.. "Spontaneous vesicle formation in catanionic mixtures of amino acid-based surfactants: Chain length symmetry effects". Langmuir 24 19 (2008): 11009-11017. http://www.scopus.com/inward/record.url?eid=2-s2.0-54549114386&partnerID=MN8TOARS.
    10.1021/la801518h
  18. Gomes, P.; Araújo, M.J.; Marques, E.F.; Falcão, S.; Brito, R.O.. "Straightforward method for the preparation of lysine-based double-chained anionic surfactants". Synthetic Communications 38 12 (2008): 2025-2036. http://www.scopus.com/inward/record.url?eid=2-s2.0-45749127438&partnerID=MN8TOARS.
    10.1080/00397910801997827
  19. Brito, R.O.; Marques, E.F.; Gomes, P.; Araújo, M.J.; Pons, R.. "Structure/property relationships for the thermotropic behavior of lysine-based amphiphiles: From hexagonal to smectic phases". Journal of Physical Chemistry B 112 47 (2008): 14877-14887. http://www.scopus.com/inward/record.url?eid=2-s2.0-57449111077&partnerID=MN8TOARS.
    10.1021/jp8042494
  20. Araújo, M.J.; Bom, J.; Capela, R.; Casimiro, C.; Chambel, P.; Gomes, P.; Iley, J.; et al. "Imidazolidin-4-one derivatives of primaquine as novel transmission-blocking antimalarials". Journal of Medicinal Chemistry 48 3 (2005): 888-892. http://www.scopus.com/inward/record.url?eid=2-s2.0-13444269006&partnerID=MN8TOARS.
    10.1021/jm0494624
  21. Gomes, P.; Araújo, M.J.; Rodrigues, M.; Vale, N.; Azevedo, Z.; Iley, J.; Chambel, P.; Morais, J.; Moreira, R.. "Synthesis of imidazolidin-4-one and 1H-imidazo[2,1-a]isoindole-2,5(3H,9bH)- dione derivatives of primaquine: Scope and limitations". Tetrahedron 60 26 (2004): 5551-5562. http://www.scopus.com/inward/record.url?eid=2-s2.0-2942564073&partnerID=MN8TOARS.
    10.1016/j.tet.2004.04.077
  22. Araújo, M.J.S.M.P.; Ragnarsson, U.; Amaral Trigo, M.J.S.A.; Almeida, M.L.S.. "Synthesis of Carbamate-protected Spermidine Homologues through Alkane-a,¿-diamines". Journal of Chemical Research - Part S 8 (1996): 366-367. http://www.scopus.com/inward/record.url?eid=2-s2.0-18144451105&partnerID=MN8TOARS.
Activities

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2018 - 2018 Síntese e estudo de compostos heteroaromáticos como potenciais antimaláricos multi-alvo
Supervisor
 Química (Master)
Universidade do Porto Faculdade de Ciências, Portugal
2018 - 2018 Síntese e estudo de compostos heteroaromáticos como potenciais antimaláricos multialvo
Supervisor
 Bioquímica (Master)
Universidade do Porto Faculdade de Ciências, Portugal
2014 - 2014 Metodologias de síntese de novos tensioativos derivados de aminoácidos
Supervisor
 Química (Master)
Universidade do Porto Faculdade de Ciências, Portugal
2014 - 2014 Novos tensioativos derivados de lisina: síntese e estudo de auto-organização supramolecular
Supervisor
 Química (Master)
Universidade do Porto Faculdade de Ciências, Portugal
Distinctions

Award

1985 Doutor Mendonça Monteiro
Universidade do Porto, Portugal