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Catarina IV Ramos is a Researcher at the Chemistry Department, of University of Aveiro, Portugal. She obtained her PhD degree in April of 2012 at the University of Aveiro and in February of 2013 she obtained a Post-doc grant with the project "New multicharged porphyrins and phthalocyanines as potential telomerase inhibitors". Her research interests are focused on the characterization and study of fragmentation patterns of porphyrins, expanded porphyrins, chlorins and phthalocyanines using electrospray mass spectrometry and multistage electrospray mass spectrometry. Hybrids porphyrin-terpyridine and porphyrin-chalcone and heterocyclic alkaloids and related compounds has been more recently object of study. An important line of action is related with the potential of these macrocycles and other heterocycles to stablish non-covalent interactions with duplex and quadruplex DNA structures, aiming to evaluate the ability of new molecules to inhibit telomerase and consequently control cancer cell proliferation. Her research activities gave rise to the publication of 27 research articles in journals indexed on Scopus, fourteen of them as first author, and nine also as corresponding author. She has participated, with oral and poster presentations, in several national and international conferences. She has a h-index of 12. She is co-editor of two special issues of the journal Molecules entitled "Photodynamic Therapy in Cancer Treatment", guest- editor of one issue in Biomolecules entitled "From G-Quadruplex Stabilization to Anticancer Therapy" and member of the referee board of several indexed journals. She is lecturing practical classes of Organic and Bioorganic Chemistry at the Chemistry Department of UA. She is regularly member of evaluation panels of final graduation projects and research fellowships. She was supervisor of two MSc students (one ongoing), mentor of one MSc student and was involved in the supervision of several undergraduate students (three ongoing) and one young researcher. She also participated in the PhD work of an international student, mentoring the gas-phase fragmentation studies of several porphyrins isolated during his studies. She was responsible by the implementation in the group of adequate biochemical and biophysical techniques to evaluate the interaction of tetrapyrrolic macrocycles and other ligands with DNA structures as it is patent by the research articles published. She has a strong relationship with the Laboratory of Pharmacology and Experimental Therapeutics, IBILI - Institute for Biomedical Imaging and Life Sciences, Faculty of Medicine, University of Coimbra, where during a research internship had the opportunity to acquire experience in biochemical techniques, highly used in her field of interest. This experience proved to be very important to expand her research expertise. A network with the Biopharmaceutical and Biomaterials research group from the Health Sciences Research Centre-University of Covilhã (CICS-UBI), an outstanding national research group in her field of interest, was also established and it is in progress. Other network has been established with Doctor Rui Vitorino from Institute of Biomedicine of Aveiro (IBIMED) a recognized expert in Proteomics that could give a significant input in the knowledge and identification of key proteins involved in cellular reorganization events upon telomerase activity inhibition. DNA G-quadruplex structures are also present in microbial genomes thus can also represent novel therapeutic targets for antimicrobial or antiviral therapy. Taking these new area of study in mind, she is member of the COST Action: CA21145 - European Network for diagnosis and treatment of antibiotic-resistant bacterial infections (EURESTOP).
Identification

Personal identification

Full name
Catarina Isabel Vicente Ramos

Citation names

  • Ramos, Catarina IV
  • Catarina IV Ramos

Author identifiers

Ciência ID
9A16-3795-8783
ORCID iD
0000-0002-0200-2005
Researcher Id
O-8191-2018
Scopus Author Id
15728406900

Email addresses

  • c.ramos@ua.pt (Professional)

Telephones

Telephone
  • 234 370360 Ext.: 23521 (Professional)

Addresses

  • University of Aveiro. Campus de Santiago, 3810-193, Aveiro, Aveiro, Portugal (Professional)

Websites

Knowledge fields

  • Exact Sciences - Chemical Sciences

Languages

Language Speaking Reading Writing Listening Peer-review
English Intermediate (B1) Advanced (C1) Upper intermediate (B2) Intermediate (B1)
French Beginner (A1) Intermediate (B1) Beginner (A1) Beginner (A1)
Education
Degree Classification
2013/02/01 - 2019/01/31
Concluded
New multicharged porphyrins and phthalocyanines as potential telomerase inhibitors (Pós-doutoramento)
Universidade de Aveiro Unidade de Investigação de Química Orgânica Produtos Naturais e Agroalimentares, Portugal
2012/04/16
Concluded
Doctoral Program in Chemistry (Doutoramento)
Universidade de Aveiro, Portugal
"Mass spectrometry of tetrapyrrolic macrocycles and their interactions with DNA. " (THESIS/DISSERTATION)
Aprovado
2005/12/12
Concluded
Advanced Biomolecular Methods (Mestrado)
Universidade de Aveiro, Portugal
"Study by mass spectrometry of the non-covalent adducts of porphyrins and oligonucleotides" (THESIS/DISSERTATION)
Aprovada
2001/09/24
Concluded
Industrial Chemistry and Management (Licenciatura)
Universidade de Aveiro, Portugal
"n/a" (THESIS/DISSERTATION)
13 valores
Affiliation

Science

Category
Host institution
Employer
2019/02/01 - Current Contracted Researcher (Research) Universidade de Aveiro Unidade de Investigação de Química Orgânica Produtos Naturais e Agroalimentares, Portugal
Universidade de Aveiro Unidade de Investigação de Química Orgânica Produtos Naturais e Agroalimentares, Portugal

Others

Category
Host institution
Employer
2013/02/01 - 2019/01/30 Pos-doc researcher Universidade de Aveiro Unidade de Investigação de Química Orgânica Produtos Naturais e Agroalimentares, Portugal
2007/05/02 - 2011/09/02 PhD student Universidade de Aveiro Centro de Espectrometria de Massa, Portugal
2007/02/01 - 2007/04/30 Researcher in the Organic Chemistry Group Universidade de Aveiro Unidade de Investigação de Química Orgânica Produtos Naturais e Agroalimentares, Portugal
2004/11/02 - 2006/11/30 Researcher at the Mass Spectrometry Center Universidade de Aveiro Centro de Espectrometria de Massa, Portugal
2004/11/02 - 2006/11/30 Researcher at the Mass Spectrometry Center Universidade de Aveiro Centro de Espectrometria de Massa, Portugal
2002/12/02 - 2004/10/29 Young researcher at the Mass Spectrometry centre. Universidade de Aveiro Centro de Espectrometria de Massa, Portugal
2001/12/01 - 2002/11/29 Research technician of the organic chemistry group in the mass spectrometry laboratory Universidade de Aveiro Unidade de Investigação de Química Orgânica Produtos Naturais e Agroalimentares, Portugal
Universidade de Aveiro, Portugal
Projects

Grant

Designation Funders
2013/02/01 - 2019/01/31 "New multicharged porphyrins and phthalocyanines as potential telomerase inhibitors"
FCT SFRH/BPD/85902/2012
Post-doc Fellow
Universidade de Aveiro Unidade de Investigação de Química Orgânica Produtos Naturais e Agroalimentares, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2006/05/02 - 2011/04/16 "Mass spectrometry of tetrapyrolic macrocycles and their interaction with DNA"
FCT SFRH/BD/30755/2006
PhD Student Fellow
Universidade de Aveiro Unidade de Investigação de Química Orgânica Produtos Naturais e Agroalimentares, Portugal
Fundação para a Ciência e a Tecnologia
Concluded

Other

Designation Funders
2022/01/02 - 2023/06/30 Development of PORphyrin-triPhenylPosphonium PhotoSensitizers for Photodynamic Inactivation of microorganisms
EXPL/QUI-QOR/0586/2021
Researcher
Universidade de Aveiro, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
Outputs

Publications

Conference abstract
  1. Pereira, Florbela; Lourenço, Ana; Aires-de-Sousa, João; Ferreira, Luísa M.; Marques, M. Manuel B.; Sousa, Emília; Branco, Paula S.. "14th Edition of the Nacional Organic Chemistry Meeting and 7th Edition of the Nacional Therapeutic Chemistry Meeting". Paper presented in 14th Edition of the Nacional Organic Chemistry Meeting and 7th Edition of the Nacional Therapeutic Chemistry Meeting, Lisboa, 2022.
    10.3390/chemproc2022011001
Conference paper
  1. Catarina I. V. Ramos, Joana F. B. Barata, ,M. Graça P. M. S. Neves, Augusto C. Tomé, José A. S. Cavaleiro. "Differentiation of New Amino-Corrole Isomers through adduct formation using Electrospray Mass Spectrometry". Paper presented in 5th Internacional Conference on Porphyrins and Phthalocyanines, Moscovo, 2008.
    Published • https://doi.org/10.1142/S1088424608000194
  2. Joana F.B. Barata, M. Graça P.M.S. Neves, Augusto C. Tomé, M. Amparo F. Faustino, Artur M.S. Silva, Catarina I.V. Ramos,. "Synthesis of novel corrole derivatives through azomethine ylides". Paper presented in 5th Internacional Conference on Porphyrins and Phthalocyanines, Moscovo, 2008.
    https://www.worldscientific.com/doi/abs/10.1142/S1088424608000194
  3. C. I. V. Ramos, C. M. Barros, M.G. Santana-Marques, A. J. Ferrer Correia, J. P. C. Tomé, A. C. Tomé, M. A. F. Faustino,.. "Study of the adducts of cationic porphyrins with small DNA duplexes by electrospray ionization mass spectrometry". Paper presented in 4th International Conference on Porphyrins and Phthalocyanines, Roma, 2006.
    Published
  4. Catarina I. V. Ramos, Cristina M. Barros, M.G. Santana-Marques, A. J. Ferrer Correia, João P. C. Tomé, Augusto C. Tomé,. "Reduction reactions of electrosprayed cationic porphyrins". Paper presented in 4th International Conference on Porphyrins and Phthalocyanins, Roma, 2006.
    Published
Conference poster
  1. Catarina IV Ramos; Nuno MM Moura, Leandro M. O. Lourenço, Maria G. P. M. S. Neves. "How the selectivity of Zn(II) ligands towards G4 DNA structures is influenced by the number and position of the positive charges". Paper presented in XXVI Encontro Galego-Portugués de Química, 2022.
  2. Ana Rita Monteiro, Catarina I. V. Ramos, M. Graça P. M. S. Neves, Tito Trindade. "Carbon nanomaterials & photosensitizers for cancer applications". 2022.
  3. A. R. Monteiro, C. I. V. Ramos, L. M. O. Lourenço, S. Fateixa, J. Rodrigues, M. G. P. M. S. Neves, T. Trindade. "Immobilization of Zinc(II) Phthalocyanines on Graphene Oxide for DNA Recognition". Paper presented in International Symposium on Medicinal Chemistry of the European Federation for Medicinal Chemistry and Chemical Biology (EFMC), 2021.
  4. C. I. V. Ramos, A. R. Monteiro, N. M. M. Moura, T. Trindade, M. A. F. Faustino, M. G. P. M. S. Neves. "Metalloporphyrins: promising G-quadruplex stabilizing ligands". Paper presented in 19th Congress of the European Society for Photobiology, 2021.
  5. Ana R. Monteiro, C. I. V. Ramos, Leandro M. O. Lourenço, Sara Fateixa, Joana Rodrigues, Maria G. P. M. S. Neves, Tito Tr. "DNA G-quadruplexes recognition by cationic zinc(II) phthalocyanine and graphene oxide hybrid materials". Paper presented in 19th Congress of the European Society for Photobiology, 2021.
  6. Catarina I. V. Ramos, Vitor A. S. Almodovar, Augusto C. Tomé, M. Graça P. M. S. Neves. "G-quadruplex intercalative interaction of a small doubly charged ligand". Paper presented in 13th National Organic Chemistry Meeting - 6th National Medicinal Chemistry Meeting, 2020.
  7. Catarina IV Ramos, Mohammed Eddahmi, Nuno M. M. Moura, Maria A. F. Faustino, El Mostapha Rakib, Maria G. S. Neves. "Evaluation of the gas-phase fragmentation pattern of new derivatives obtained from the reaction of ß-nitro-meso-tetraphenylporphyrin with p-chlorophenoxyacetonitrile". Paper presented in 13th National Organic Chemistry Meeting and the 6th National Medicinal Chemistry Meeting, 2020.
  8. Catarina IV Ramos, Ana R Monteiro, Nuno MM Moura, M. Graça PMS Neves. "The influence of metal core in the formation and stability of G-quadruplex/porphyrin adducts". Paper presented in XXVI Encontro Nacional da Sociedade Portuguesa de Química, 2019.
  9. N. M. M. Moura, Catarina I. V. Ramos, M. A. F. Faustino, A. Almeida, J. A. S. Cavaleiro, C. Lodeiro C, M. G. P. M. S. Ne. "Cationic porphyrin-terpyridine derivatives: Synthesis, characterization and biological evaluation". Paper presented in XXV Encontro Nacional da Sociedade Portuguesa de Química, 2017.
  10. Catarina I.V. Ramos, M. Graça O. Santana-Marques. "Mass Spectrometry for the Study of G-quadruplex - porphyrin adducts". Paper presented in Research Day - Universidade de Aveiro, 2011.
  11. Catarina I.V. Ramos, M. Graça O. Santana-Marques, João P. C. Tomé. "Studying G-quadruplex - porphyrin adducts by Electrospray Mass Spectrometry (ESI-MS)". Paper presented in 4th Portuguese Mass Spectrometry Meeting, 2010.
  12. J. Madureira, S. Quintal, N. P. Farrell, C.I.V. Ramos, M. G. O. Santana-Marques, M. Marques, C. Maia, L. Campino. "Copper and Zinc Dipyridophenazine Complexes with Leishmanicidal Activity". Paper presented in XV Brazilian Meeting on Organic Chemistry, 2010.
  13. Patrícia M. R. Pereira, Catarina I. V. Ramos, M. G. O. Santana-Marques, Rodrigo de Paul. "Unexpected gas-phase behaviour of H2-TDMImP in ESI negative and positive ion mode". Paper presented in 2nd Portuguese Young Chemists Meeting (2PYCheM), 2010.
  14. Catarina I.V. Ramos, Patrícia M.R. Pereira, M.Graça O. Santana-Marques, Rodrigo De Paula, M. Graça P. M.S. Neves, José. "Unexpectedgas-phase behaviour of H2TDMImP". Paper presented in 8º Encontro Nacional de Química Orgânica, 2009.
  15. Catarina I.V. Ramos, M. Graça O. Santana-Marques, João P. C. Tomé. "Cationic Porphyrins/G-Quadruplexes adducts: a study by Electrospray Mass Spectrometry (ESI-MS)". Paper presented in 16th European Symposium on Organic Chemistry, 2009.
  16. Teresa M. Santos, André Paiva, João Madureira, Catarina I. V Ramos, M. Graça Santana-Marques. "Synthesis and characterization by ESI-MS and ESI-MS/MS of {Ru[9]aneS3} coordination compounds with potentially tridentate beta-aminoacids". Paper presented in 38th International Conference on Coordination Chemistry, 2008.
  17. C. I. V. Ramos, M. Graça Santana-Marques, V. Vaz Serra, A. J. Ferrer Correia, M. A. Faustino, M. Graça P. M. S. Neves. "Study of the interactions of neutral and cationic porphyrins with a GCGCGC duplex by ESI-MS". Paper presented in 4th Transmediterranean Colloquium on Heterocyclic Chemistry, 2006.
  18. Catarina IV Ramos. "Study of interactions of a tetramer duplex with several Ruthenium(II) complexes and cationic porphyrins by ESIMS". Paper presented in 1st European Conference on Chemistry for Life Sciences - Understanding the Chemial Mechanisms of Life, 2005.
    10.1109/hsi.2011.5937401
Journal article
  1. Moura, Nuno M. M.; Cavaleiro, José A. S.; Neves, Maria Graça P. M. S.; Ramos, Catarina I. V.. "opp-Dibenzoporphyrin Pyridinium Derivatives as Potential G-Quadruplex DNA Ligands". Molecules 28 17 (2023): 6318. http://dx.doi.org/10.3390/molecules28176318.
    10.3390/molecules28176318
  2. Monteiro, Ana R.; Ramos, Catarina I. V.; Fateixa, Sara; Neves, Maria G.P.M.S.; Trindade, Tito. "Arrays of graphene-quantum dots-supported DNA oligonucleotides as self-indicating porphyrin carriers". New Journal of Chemistry 47 39 (2023): 18130-18142. http://dx.doi.org/10.1039/d3nj03280a.
    Published • 10.1039/d3nj03280a
  3. Ana Rita Rodrigues Vilares Cabral Monteiro; Catarina IV Ramos; Leandro Miguel Oliveira Lourenço; Sara Fateixa; Joana Catarina Ferreira Rodrigues; Maria da Graça de Pinho Morgado Silva Neves; Tito Trindade. Corresponding author: Tito Trindade. "Interfacial assembly of zinc(II) phthalocyanines on graphene oxide (GO): Stable “turn-off-on” nanoplatforms to detect G-quadruplexes (G4)". Journal of Colloid and Interface Science 627 (2022): 900-912. http://dx.doi.org/10.1016/j.jcis.2022.07.075.
    10.1016/j.jcis.2022.07.075
  4. Joana F. B. Barata; Paula S. S. Lacerda; Maria Graça P. M. S. Neves; José A. S. Cavaleiro; Catarina I. V. Ramos; Augusto C. Tomé; Paulo E. Abreu; Alberto A. C. C. Pais. "Reaction of Corroles with Sarcosine and Paraformaldehyde: A New Facet of Corrole Chemistry". International Journal of Molecular Sciences (2022): https://doi.org/10.3390/ijms232113581.
    10.3390/ijms232113581
  5. Ramos, Catarina I.V.; Almodôvar, Vitor A.S.; Candeias, Nuno R.; Santos, Tiago; Cruz, Carla; Neves, M. Graça P.M.S.; Tomé, Augusto C.. "Diketopyrrolo[3,4-c]pyrrole derivative as a promising ligand for the stabilization of G-quadruplex DNA structures". Bioorganic Chemistry 122 (2022): 105703. http://dx.doi.org/10.1016/j.bioorg.2022.105703.
    10.1016/j.bioorg.2022.105703
  6. Catarina IV Ramos; Ana Rita Monteiro; Nuno M. M. Moura; M A F Faustino; Tito Trindade; Neves M.G.P.M.S.. Corresponding author: Catarina IV Ramos. "The Interactions of H2TMPyP, Analogues and Its Metal Complexes with DNA G-Quadruplexes - An Overview". Biomolecules (2021): https://www.mdpi.com/2218-273X/11/10/1404.
    10.3390/biom11101404
  7. Jéssica Lopes-Nunes, Josué Carvalho, Joana Figueiredo, Catarina I.V. Ramos, Leandro M.O. Lourenço, João P.C. Tomé, Maria; Cruz, Carla. Corresponding author: Cruz, Carla. "Phthalocyanines for G-quadruplex aptamers binding". Bioorganic Chemistry (2020): http://dx.doi.org/10.1016/j.bioorg.2020.103920.
    10.1016/j.bioorg.2020.103920
  8. Mohammed Eddahmi, Nuno M.M. Moura, Catarina I.V Ramos, Latifa Bouissane, Maria A.F. Faustino, José A.S. Cavaleiro, El M. "An insight into the vicarious nucleophilic substitution reaction of 2-nitro-5,10,15,20-tetraphenylporphyrin with p-chlorophenoxyacetonitrile: synthesis and gas-phase fragmentation studies". Arabian Journal of Chemistry (2020): http://dx.doi.org/10.1016/j.arabjc.2020.04.022.
    10.1016/j.arabjc.2020.04.022
  9. Calmeiro, Joana M.D.; Dias, Cristina J.; Ramos, Catarina I.V.; Almeida, Adelaide; Tomé, João P.C.; Faustino, Maria A.F.; Lourenço, Leandro M.O.. "Comparative photodynamic inactivation of bioluminescent E. coli by pyridinium and inverted pyridinium chlorins". Dyes and Pigments 173 (2020): 107410. http://dx.doi.org/10.1016/j.dyepig.2019.03.021.
    Published • 10.1016/j.dyepig.2019.03.021
  10. Lourenço, Leandro M. O.; Rocha, Deisy M. G. C.; Ramos, Catarina I. V.; Gomes, Maria C.; Almeida, Adelaide; Faustino, Maria A. F.; Almeida Paz, Filipe A.; et al. "Photoinactivation of Planktonic and Biofilm Forms of Escherichia coli through the Action of Cationic Zinc(II) Phthalocyanines". ChemPhotoChem 3 5 (2019): 251-260. http://dx.doi.org/10.1002/cptc.201900020.
    10.1002/cptc.201900020
  11. Catarina IV Ramos; Susana P. Almeida; Leandro M. O. Lourenço; Patrícia M. R. Pereira; Rosa Fernandes; M A F Faustino; João P. C. Tomé; et al. "Multicharged Phthalocyanines as Selective Ligands for G-Quadruplex DNA Structures". Molecules (2019): https://www.mdpi.com/1420-3049/24/4/733.
    10.3390/molecules24040733
  12. Monteiro, A.R.; Ramos, C.I.V.; Fateixa, S.; Moura, N.M.M.; Neves, M.G.P.M.S.; Trindade, T.. "Hybrids Based on Graphene Oxide and Porphyrin as Tools for Detection and Stabilization of DNA G-Quadruplexes". ACS Omega 3 9 (2018): 11184-11191. http://www.scopus.com/inward/record.url?eid=2-s2.0-85053440353&partnerID=MN8TOARS.
    10.1021/acsomega.8b01366
  13. Ramos, C.I.; Figueira, F.; Polêto, M.D.; Amado, F.M.; Verli, H.; Tomé, J.P.; Neves, M.G.P.. "ESI-MS/MS of expanded porphyrins: A look into their structure and aromaticity". Journal of Mass Spectrometry 51 5 (2016): 342-349. http://www.scopus.com/inward/record.url?eid=2-s2.0-84969132765&partnerID=MN8TOARS.
    10.1002/jms.3760
  14. Moura, N.M.M.; Ramos, C.I.V.; Linhares, I.; Santos, S.M.; Faustino, M.A.F.; Almeida, A.; Cavaleiro, J.A.S.; et al. "Synthesis, characterization and biological evaluation of cationic porphyrin-terpyridine derivatives". RSC Advances 6 112 (2016): 110674-110685. http://www.scopus.com/inward/record.url?eid=2-s2.0-84997839875&partnerID=MN8TOARS.
    10.1039/c6ra25373c
  15. Ramos, C.I.V.; Moura, N.M.M.; Santos, S.M.F.; Faustino, M.A.; Tomé, J.P.C.; Amado, F.M.L.; Neves, M.G.P.M.S.. "An insight into the gas-phase fragmentations of potential molecular sensors with porphyrin-chalcone structures". International Journal of Mass Spectrometry 392 (2015): 164-172. http://www.scopus.com/inward/record.url?eid=2-s2.0-84947293766&partnerID=MN8TOARS.
    10.1016/j.ijms.2015.10.008
  16. Iglesias, B.A.; Barata, J.F.B.; Ramos, C.I.V.; Santana-Marques, M.G.; Neves, M.G.P.M.S.; Cavaleiro, J.A.S.. "Adventures in corrole features by electrospray ionization mass spectrometry studies". RSC Advances 4 32 (2014): 16824-16838. http://www.scopus.com/inward/record.url?eid=2-s2.0-84898005436&partnerID=MN8TOARS.
    10.1039/c3ra47788f
  17. Ramos, C.I.V.; Pereira, P.M.R.; Santana-Marques, M.G.; De Paula, R.; Simões, M.M.Q.; Neves, M.G.P.M.S.; Cavaleiro, J.A.S.. "Imidazole and imidazolium porphyrins: Gas-phase chemistry of multicharged ions". Journal of Mass Spectrometry 49 5 (2014): 371-379. http://www.scopus.com/inward/record.url?eid=2-s2.0-84900033480&partnerID=MN8TOARS.
    10.1002/jms.3350
  18. Madureira, J.; Ramos, C.I.V.; Marques, M.; Maia, C.; De Sousa, B.; Campino, L.; Santana-Marques, M.G.; Farrell, N.. "Nonclassic metallointercalators with dipyridophenazine: DNA interaction studies and leishmanicidal activity". Inorganic Chemistry 52 15 (2013): 8881-8894. http://www.scopus.com/inward/record.url?eid=2-s2.0-84881170564&partnerID=MN8TOARS.
    10.1021/ic401067d
  19. Ramos, C.I.V.; Santana-Marques, M.G.; Ferrer-Correia, A.J.; Barata, J.F.B.; Tomé, A.C.; Neves, M.G.P.M.S.; Cavaleiro, J.A.S.; et al. "Differentiation of aminomethyl corrole isomers by mass spectrometry". Journal of Mass Spectrometry 47 4 (2012): 516-522. http://www.scopus.com/inward/record.url?eid=2-s2.0-84861541541&partnerID=MN8TOARS.
    10.1002/jms.2973
  20. Ramos, C.I.V.; Tomé, J.P.C.; Santana-Marques, M.G.. "Charge and substituent effects on the stability of porphyrin/G-quadruplex adducts". Journal of Mass Spectrometry 47 2 (2012): 173-179. http://www.scopus.com/inward/record.url?eid=2-s2.0-84857475177&partnerID=MN8TOARS.
    10.1002/jms.2048
  21. Silva, E.M.P.; Ramos, C.I.V.; Pereira, P.M.R.; Giuntini, F.; Faustino, M.A.F.; Tomé, J.P.C.; Tomé, A.C.; et al. "Cationic ß-vinyl substituted meso-tetraphenylporphyrins:". Journal of Porphyrins and Phthalocyanines 16 1 (2012): 101-113. http://www.scopus.com/inward/record.url?eid=2-s2.0-84860494332&partnerID=MN8TOARS.
    10.1142/S1088424611004373
  22. Cardote, T.A.F.; Barata, J.F.B.; Faustino, M.A.F.; Preuß, A.; Neves, M.G.P.M.S.; Cavaleiro, J.A.S.; Ramos, C.I.V.; Santana-Marques, M.G.O.; Röder, B.. "Pentafluorophenylcorrole-d-galactose conjugates". Tetrahedron Letters 53 47 (2012): 6388-6393. http://www.scopus.com/inward/record.url?eid=2-s2.0-84867853733&partnerID=MN8TOARS.
    10.1016/j.tetlet.2012.09.038
  23. Izquierdo, R.A.; Madureira, J.; Ramos, C.I.V.; Santana-Marques, M.G.O.; Santos, T.M.. "Investigation of the coordination modes of tris(pyrazolylmethane)/1,4,7- trithiacyclononane ruthenium(II) complex ions by electrospray ionization mass spectrometry". International Journal of Mass Spectrometry 301 1-3 (2011): 143-150. http://www.scopus.com/inward/record.url?eid=2-s2.0-79953226234&partnerID=MN8TOARS.
    10.1016/j.ijms.2010.08.007
  24. Ramos, C.I.V.; Santana-Marques, M.G.; Enes, R.F.; Tomé, A.C.; Cavaleiro, J.A.S.; Nogueras, M.. "Gas-phase fragmentation of protonated C60-pyrimidine derivatives". Journal of Mass Spectrometry 44 6 (2009): 911-919. http://www.scopus.com/inward/record.url?eid=2-s2.0-67649160622&partnerID=MN8TOARS.
    10.1002/jms.1564
  25. Ramos, C.I.V.; Graça Santana-Marques, M.. "Electrospray mass spectrometry for the study of the non-covalent interactions of porphyrins and duplex desoxyribonucleotides". Journal of Porphyrins and Phthalocyanines 13 4-5 (2009): 518-523. http://www.scopus.com/inward/record.url?eid=2-s2.0-68349154395&partnerID=MN8TOARS.
  26. Ramos, C.I.V.; Santana-Marques, M.G.; Ferrer Correia, A.J.; Tomé, J.P.C.; Alonso, C.M.; Tomé, A.C.; Neves, M.G.P.M.S.; Cavaleiro, J.A.S.. "Reduction and adduct formation from electrosprayed solutions of porphyrin salts". Journal of Mass Spectrometry 43 6 (2008): 806-813. http://www.scopus.com/inward/record.url?eid=2-s2.0-46849095862&partnerID=MN8TOARS.
    10.1002/jms.1378
  27. Jordão, C.I.C.; Farinha, A.S.F.; Enes, R.F.; Tomé, A.C.; Silva, A.M.S.; Cavaleiro, J.A.S.; Ramos, C.I.V.; et al. "Synthesis of [60]fullerene-glycopyranosylaminopyrimidin-4-one conjugates". Tetrahedron 64 19 (2008): 4427-4437. http://www.scopus.com/inward/record.url?eid=2-s2.0-41549138648&partnerID=MN8TOARS.
    10.1016/j.tet.2008.02.057
  28. Ramos, C.I.V.; Santana Marques, M.G.; Correia, A.J.F.; Serra, V.V.; Tomé, J.P.C.; Tomé, A.C.; Neves, M.G.P.M.S.; Cavaleiro, J.A.S.. "Reduction of Cationic Free-Base meso-Tris-N-Methylpyridinium-4-yl Porphyrins in Positive Mode Electrospray Ionization Mass Spectrometry". Journal of the American Society for Mass Spectrometry 18 4 (2007): 762-768. http://www.scopus.com/inward/record.url?eid=2-s2.0-33947306734&partnerID=MN8TOARS.
    10.1016/j.jasms.2006.12.009
  29. Ramos, C.I.V.; Barros, C.M.; Fernandes, A.M.; Santana-Marques, M.G.; Correia, A.J.F.; Tomé, J.P.C.; Carrilho, M.D.C.T.; et al. "Interactions of cationic porphyrins with double-stranded oligodeoxynucleotides: A study by electrospray ionisation mass spectrometry". Journal of Mass Spectrometry 40 11 (2005): 1439-1447. http://www.scopus.com/inward/record.url?eid=2-s2.0-27944438376&partnerID=MN8TOARS.
    10.1002/jms.936
Journal issue
  1. Catarina IV Ramos; Cruz, Carla; Maria Graça Neves. "Special Issue "From G-Quadruplex Stabilization to Anticancer Therapy"". Biomolecules (2021):
    Editor
  2. Catarina IV Ramos; Carlos J.P. Monteiro; Maria Amparo F Faustino. "Special issue "Photodynamic Therapy in Cancer Treatment 2021"". Molecules (2021): https://www.mdpi.com/journal/molecules/special_issues/PDT_2021.
    Coeditor
  3. Catarina IV Ramos; Carlos J. P. Monteiro; M. Amparo F. Faustino. "Special issue "Photodynamic Therapy in Cancer Treatment"". Molecules (2020): https://www.mdpi.com/journal/molecules/special_issues/PDT.
    Coeditor
Online resource
  1. Catarina IV Ramos. Issue Cover design "The interaction of (metallo)porphyrins with DNA G-Quadruplexes". 2021. https://www.mdpi.com/files/uploaded/covers/biomolecules/big_cover-biomolecules-v11-i10.png.
Thesis / Dissertation
  1. Catarina IV Ramos. "Mass spectrometry of tetrapyrrolic macrocycles and their interactions with DNA". PhD, Universidade de Aveiro Centro de Espectrometria de Massa, 2012.
  2. Catarina IV Ramos. "Study by mass spectrometry of the non-covalent adducts of porphyrins and oligonucleotides". Master, Universidade de Aveiro, 2005.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2024/01 "Blocking replication of tumour cells with G-quadruplex DNA stabilizing ligands" 15th National Organic Chemistry Meeting (15ENQO), and the 8th National Medicinal Chemistry Meeting (8ENQT)
Sociedade Portuguesa da Quimica; Associacion de Guimicos de Galiza (Faro, Portugal)
2023/11/23 "G-quadruplex DNA stabilization - a strategy to block replication of tumour cells" XXVII Encontro Luso-Galego de Química
Sociedade Portuguesa da Quimica; Associacion de Guimicos de Galiza (Porto, Portugal)
2023/03 "Tetrapyrrolic macrocycles: an insight on their biological importance, occurrence, and applications." International Conference on Applied (Bio)Geochemistry (ICAG 2023)
(Fkih Ben Salah, Morocco, Morocco)
2023/03 "Porphyrinoids: Synthesis and their Role in Medical and Environmental Remediation Applications" International convention on colorants
(Mumbai, India,, India)
2022/11 Development of Photoactive Materials for Photodynamic Therapy Based Applications XXVI Encontro Galego-Portugués de Química
Sociedade Portuguesa da Quimica; Associacion de Guimicos de Galiza (Santiago de Compostela, Spain)
2022/11 Recent advances in cancer therapies via carbon nanomaterials functionalized with porphyrins and analogues XXVI Encontro Galego-Portugués de Química
Sociedade Portuguesa da Quimica; Associacion de Guimicos de Galiza (Santiago de Compostela, Spain)
2022/07 Secondary DNA structures as an anticancer strategy: the role of stabilization ligands 5th International Caparica Conference on Chromogenic and Emissive Materials 2022
Proteomass Scientific Society, BIOSCOPE Research Team, NOVA University Lisbon ( Costa da Caparica, Portugal)
2022/04/22 An attractive ligand for the development of G4 labelling probes 14th National Organic Chemistry Meeting & 7th National Medicinal Chemistry Meeting (14ENQO&7ENQT
Sociedade Portuguesa da Quimica (Costa da Caparica, Portugal)
2022/04/20 Graphene Oxide Assisted Delivery of Cationic Zn(II) Phthalocyanines to DNA G-Quadruplexes 14th National Organic Chemistry Meeting & 7th National Medicinal Chemistry Meeting (14ENQO&7ENQT
(Costa da Caparica)
2018/11 "Afinity and seletivity of cationic porphyrins and phthalocyanines to different DNA strutures: competitive screening" XXIV Luso Galician Meeting of Chemistry
Portuguese Chemistry Society (SPQ) (Porto, Portugal)
2018/07 Porphyrin@GO hybrid materials as DNA G-quadruplex detectors and stabilizers International Conference on Nanomaterials Science and Mechanical Engineering
(Aveiro, Portugal)
2018/07 Porphyrin@GO hybrid materials as DNA G-quadruplex detectors and stabilizers International Conference on Nanomaterials Science and Mechanical Engineering
Centre for Mechanical Technology and Automation (TEMA), Universty of Aveiro (Aveiro, Portugal)
2017/07 “Combined ammonium and pyridinium Zinc(II) phthalocyanines and their photodynamic effect on cell suspensions and biofilms of Escherichia coli”, , Lisboa, Portugal, Julho 2017 XXV National Meeting Portuguese Chemistry Society
Portuguese Chemistry Society (Lisboa, Portugal)
2016/07 Stability studies of porphyrin / dna adducts 34th Youth Science Meeting
(Lisboa, Portugal)
2014/12 “Electrospray mass spectrometry in the interrogation of specific analytes: G-quadruplex DNA - porphyrin adducts” 1st Caparica Christmas Conference on Sample Treatment
(Lisboa, Portugal)
2010/12 "Mass Spectrometry of Oligonucleotide Noncovalent Aducts" 4th Portuguese Mass Spectrometry Meeting
(Lisboa, Portugal)
2010/11 "G-quadruplexes: study of the interactions with cationic porphyrins by electrospray ionization mass spectrometry" XVI Encontro Luso-Galego de Química
(Aveiro, Portugal)
2010/11 Study of the non-covalent adducts of double stranded oligonucleotides and cationic porphyrins with potential therapeutic aplication XVI Encontro Luso-Galego de Química
(Aveiro, Portugal)
2010/04 "Gas-Phase Chemistry of Cationic Porphyrins" 217th ECS Meeting, Vancouver
(Vancouver, Canada)

Supervision

Thesis Title
Role
Degree Subject (Type)
Institution / Organization
2024/01 - Current Application of triphenylphosphonium-porphyrin conjugates as photosensitizers in photodynamic therapy
Supervisor
Biotechnology (Degree)
2024/01 - Current Assessment of the stability of phthalocyanine-G-quadruplexes DNA adducts
Supervisor
Biochemistry (Degree)
Universidade de Aveiro, Portugal
2023/09/20 - Current Study of the potential of acridone-type ligands for stabilization of DNA structures
Supervisor
Mestrado em Métodos Biomoleculares Avançados (Master)
Universidade de Aveiro Departamento de Química, Portugal
2021/10/06 - Current Telomerase inhibition - identification and structural caracterization of ligands and key proteins
Supervisor
Biotecnologia (Master)
Universidade de Aveiro, Portugal
2023/03/02 - 2023/07/21 Study of the interaction of DNA structures with metal complexes with anticancer potential
Supervisor
Biochemistry (Degree)
Universidade de Aveiro, Portugal
2023/02 - 2023/07 Evaluation of the ability of new heteropolycyclo@triphenylphosphonium conjugates to stabilize DNA structures
Co-supervisor
Biotecnologia (Degree)
Universidade de Aveiro, Portugal
2022/03/02 - 2022/07/18 Study of formation and stability of adducts DNA - porphyrins
Supervisor
Bioquímica (Degree)
Universidade de Aveiro, Portugal
2022/03/02 - 2022/07/18 Evaluation of the potential of different ligands to telomerase inhibition
Supervisor
Biotecnologia (Degree)
Universidade de Aveiro, Portugal
2022/03/02 - 2022/07/07 Study of formation and stability of adducts of DNA with multicharged ligands
Supervisor
Bioquímica (Degree)
Universidade de Aveiro, Portugal
2021/03/08 - 2021/07/22 Study of the interaction of porphyrin ligands and DNA structures
Supervisor
Bioquímica (Degree)
Universidade de Aveiro, Portugal
2021/03/08 - 2021/07/21 Study of the interaction between porphyrins and DNA structures - double chain and G-quadruplexes
Supervisor
Bioquímica (Degree)
Universidade de Aveiro, Portugal
2020/02/17 - 2020/07/24 "Study of the formation and stability of adducts of DNA with multicharged ligands"
Supervisor
Bioquímica (Degree)
Universidade de Aveiro, Portugal
2019/02/04 - 2019/07/18 "Study of the formation and stability of adducts of DNA with multicharged phthalocyanines”
Supervisor
Biotecnologia (Degree)
Universidade de Aveiro, Portugal
2019/02/04 - 2019/07/17 "Study of the formation and stability of adducts of DNA with beta substituted porphyrins”
Supervisor
Bioquímica (Degree)
Universidade de Aveiro, Portugal
2017/10/01 - 2018/12/07 "Selectivity of cationic porphyrins: double chain versus high order DNA adducts”
Supervisor
Bioquimica Clínica (Master)
Universidade de Aveiro Unidade de Investigação de Química Orgânica Produtos Naturais e Agroalimentares, Portugal
2018/02/02 - 2018/07/14 "Study of stability of adducts of DNA with porphyrins with different structural characteristics”
Supervisor
Biotecnologia (Degree)
Universidade de Aveiro, Portugal
2018/02/02 - 2018/07/14 "Study of stability of adducts of DNA with metallated porphyrins”
Supervisor
Bioquímica (Degree)
Universidade de Aveiro, Portugal
2016/02/01 - 2016/06/30 Study of stability of DNA/porphyrins adducts”
Supervisor
Bioquímica (Degree)
Universidade de Aveiro, Portugal
2009/09/03 - 2010/06/30 "Synthesis, characterization and study of gas-phase behavior of cationic porphyrins"
Co-supervisor of Patricia Manuela Ribeiro Pereira
Universidade de Aveiro Centro de Espectrometria de Massa, Portugal

Event participation

Activity description
Type of event
Event name
Institution / Organization
2023/01 - Current Member of the COST Action: CA21145 - European Network for diagnosis and treatment of antibiotic-resistant bacterial infections (EURESTOP).
Other
2023/02/14 - 2023/02/14 A virtual global women breakfast aiming in the theme "Oceans that break barriers"
Other
Global Women's Breakfast
Sociedade Portuguesa de Química, Portugal
2022/06/06 - 2022/06/09 "Hands-on NMR-based Metabolomics: principles, methods, and applications" provided an introduction to NMR-based metabolomics, describing the methods used to study the metabolome, from sample preparation to the analysis of NMR spectra and metabolomics data. The course was given in a hybrid format: theoretical lectures online; hands-on sessions on-site.
Workshop
Full course of "Hands-on NMR-based Metabolomics: principles, methods and applications"
2021/05/26 - 2021/05/26 1st Spring Virtual Meeting on Medicinal Chemistry
Conference
1st Spring Virtual Meeting on Medicinal Chemistry
Sociedade Portuguesa de Química, Portugal
2021/05/18 - 2021/05/18 A one-day international congress in the framework of the International Day of Light 2021
Conference
The 5th Photodynamic Day
2021/02/19 - 2021/02/19 Seminar for a Healthy Science dedicated to Emerging technologies and their Impact on health - "Metal Complexes as Diagnostic and Therapeutics" by Prof. Gilles Gasser, Chimie ParisTech - PSL University
Seminar
2nd seminar of the series: iMed.ULisboa: Metal Complexes as Diagnostic and Therapeutics
Universidade de Lisboa, Portugal
2021/02/09 - 2021/02/09 A virtual global women breakfast aiming to show the "Empowering Diversity in Science"
Other
Global Women's Breakfast
Sociedade Portuguesa de Química, Portugal
2020/12/23 - 2020/12/23 Three amazing lectures by Nuno Maulide (Vienna University), Ana Petronilho (ITQB-NOVA) and Daniel Santos (REQUIMTE/FCUP) about the discovery and development of new anti-cancer agents
Symposium
Virtual Symposium "DRUG DISCOVERY FOR ANTI-CANCER AGENTS"
University of Lisbon/Faculty of Pharmacy, Portugal
2020/07/06 - 2020/07/17 "Docência +" is a joint initiative, within Aveiro University through the Teaching and Learning Center of the Office of Reitoria, and UMinho, through the IDEA Center open to teachers and researchers who have academic activity in the academic year 2020/2021. It was propose to participants, in a spirit of sharing, to develop an innovative plan for a course in which they are involved. Training sessions and a personalized work project occur, accompanied by a pair of UMinho and AU mentors.
Other
Docência +
Universidade de Aveiro, Portugal

Universidade do Minho, Portugal
2019/10/10 - 2019/10/12 Techdays - an event dedicated to technology and innovation, which seeks to establish itself as a reference event at national level
Exhibition
Techdays - BUILDING OUR FUTURE
2019/03/06 - 2019/03/06 Participation in workshop "Animal models of disease - 2nd edition"
Workshop
Universidade de Aveiro Unidade de Investigação de Química Orgânica Produtos Naturais e Agroalimentares, Portugal

Universidade de Aveiro Instituto de Biomedicina, Portugal
2018/10/11 - 2018/10/13 Techdays - an event dedicated to technology and innovation, which seeks to establish itself as a reference event at national level
Exhibition
Techdays
2016/10 - 2017/02 Irternship in Laboratory of Pharmacology and Experimental Therapeutics, IBILI ¿ Institute for Biomedical Imaging and Life Sciences, Faculty of Medicine, University of Coimbra (IBILI/UC. Opportunity of gaining experience in in vitro assays highly used and important in the field of research.
Other
CNC.IBILI, Portugal
2015/02 - 2015/12 Research stage in Laboratory of Pharmacology and Experimental Therapeutics. Opportunity of gaining experience in biochemical techniques, highly used in the field of research.
Other
CNC.IBILI, Portugal
2010/09/06 - 2010/09/07 Proteomics Workshop
Workshop
Proteomics Workshop

Association member

Society Organization name Role
2009/06 - Current Sociedade Portuguesa de Química (SPQ) - Portuguese Society of Chemistry (n. 5131)
2006/12 - Current International society of porphyrins and phthalocyanines (n.998)

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2024/02/20 - Current Pratical classes of "Bioorganic Chemistry" Undergraduation (Licenciatura)
2023/10/10 - Current Lecturer of practical classes of Chemistry Fundaments (Licenciatura) Universidade de Aveiro Departamento de Química, Portugal
2020/02/18 - Current Monitor of practical classes of "Bioorganic Chemistry" Biotechnology (Licenciatura) Universidade de Aveiro Departamento de Química, Portugal
2023/10 - 2024/12/15 Lecturer of practical classes of Chemistry Fundaments Chemistry Fundaments (Licenciatura) Universidade de Aveiro, Portugal
2023/02 - 2023/07/30 Lecturer of practical classes of Bioorganic chemistry (Licenciatura) Universidade de Aveiro, Portugal
2022/09/30 - 2023/01/12 Lecturer of practical classes of Chemistry Fundaments Universidade de Aveiro, Portugal
2021/10/01 - 2022/02/06 Lecturer of practical classes of Biochemistry - Organic Chemistry (Licenciatura) Universidade de Aveiro, Portugal
2021/02/01 - 2021/06/01 Monitor of practical classes of "Bioorganic Chemistry" (Licenciatura) Universidade de Aveiro, Portugal
2020/10/10 - 2021/02/27 Monitor of practical classes of “Organic Chemistry - Physical Chemistry” (Licenciatura) Universidade de Aveiro, Portugal
2010/10/03 - 2010/12/17 Practical classes of "Elements of Physical-Chemistry" (Licenciatura) Universidade de Aveiro Departamento de Química, Portugal
2009/10/02 - 2009/12/18 Practical classes of "Elements of Physical-Chemistry" (Licenciatura) Universidade de Aveiro Departamento de Química, Portugal
2008/10/01 - 2008/12/19 Practical classes of "Elements of Physical-Chemistry" (Licenciatura) Universidade de Aveiro, Portugal

Journal scientific committee

Journal title (ISSN) Publisher
2021/06/24 - Current Biomolecules MDPI
2018/07 - Current Dalton Transactions (1477-9234) The Royal Society of Chemistry
2014/05 - Current Journal of Porphyrins and Phthalocyanines (1099-1409) World Scientific
2018/03/21 - 2022/02/11 International Journal of Molecular Sciences (1422-0067) MDPI AG
2020/10/20 - 2021/02 Genes MDPI
2019/01/28 - 2020/01/13 Molecules (1420-3049) MDPI AG

Mentoring / Tutoring

Topic Student name
2018/09/15 - Current Porphyrin functionalized graphene oxide for telomerase inhibition Ana Rita Rodrigues Vilares Cabral Monteiro

Other jury / evaluation

Activity description Institution / Organization
2016/07/01 - 2022/07/20 Member of the evaluation panel of the final graduation project monographs of the Organic Chemistry group Universidade de Aveiro, Portugal
2022/02/01 - 2022/03/15 Full member of the selection jury of a research grant in the scope of the project PORP2SENS - Development of PORphyrin-triPhenylPosphonium PhotoSensitizers for Photodynamic Inactivation of microorganisms” (EXPL/QUI-QOR/0586/2021) Universidade de Aveiro, Portugal
Distinctions

Award

2021 Best Poster on the 19th Congress of the European Society for Photobiology
European Society for Photobiology, Austria
2016 3 Award on the 34th Youth Science Meeting
Portuguese Youth Science Association (AJC) , Portugal