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Ana Margarida Duarte Salgueiro is a researcher at the Center for Neuroscience and Cell Biology (CNC-UC) in the “Gene and Stem Cell Therapies for Brain Disorders” group. She completed her integrated master's in Pharmaceutical Sciences at the University of Coimbra in September 2022, earning a distinction (18/20) for her thesis on gene therapy strategies for Huntington's Disease.¿ Ana contributed to two projects on Spinocerebellar ataxia type 3/Machado-Joseph Disease, co-authoring communications at the 29th European Society of Gene and Cell Therapy Congress. She participated in the "ReSet" project as a Voluntary Researcher and later secured a fellowship in March 2023 to develop viral vector-based strategies against SARS-CoV-2. In September 2023, she joined the European JPND-funded NEURODIET project, focusing on dietary interventions in neurodegenerative diseases.¿ Her skills include cell culture, Western blotting, qPCR, immunohistochemistry, nucleic acid/protein extraction and quantification, cellular transfection, and animal experimentation. Ana holds FELASA B certification and DGAV accreditation for laboratory animal research. She has attended various advanced courses and delivered two oral presentations during Science and Technology Week.¿ Ana authored a conference abstract and a review article on the ketogenic diet in neurodegenerative disorders. She is a member of the Huntington Disease-Community Advisory Board and an ambassador for the Huntington’s Disease Youth Organization (HDYO). Her personal connection to Huntington’s Disease fuels her commitment to advancing research.¿ In recognition of her dedication, Ana received a Travel Grant to attend the HDYO International Young Adult Congress in Prague, March 2025. She has also contributed to organizing scientific events like the Mini-Symposium “Fundamental Research on Ageing: Why It Matters?” (2024) and the NEURODIET Consortium Meeting (2023). Additionally, she mentors younger researchers and holds an Advanced Certificate in English from the Cambridge English Language Assessment.
Identification

Personal identification

Full name
Ana Margarida Duarte Salgueiro

Citation names

  • Salgueiro, Ana Margarida Salgueiro

Author identifiers

Ciência ID
9C16-09F2-7174
ORCID iD
0000-0002-9713-3015

Email addresses

  • anasalgueiro99@gmail.com (Professional)
  • asalgueiro@cnc.uc.pt (Professional)
  • anasalgueiro99@hotmail.com (Personal)

Knowledge fields

  • Medical and Health Sciences - Health Sciences
  • Natural sciences - Biological Sciences - Cell Biology
  • Natural sciences - Biological Sciences - Molecular Biology
  • Natural sciences - Biological Sciences - Biology
  • Medical and Health Sciences - Medical Biotechnology - Health-Related Biotechnology
  • Medical and Health Sciences - Medical Biotechnology - Technologies Involving the Manipulation of Cells, Tissues, Organs or the Whole Organism
  • Medical and Health Sciences - Medical Biotechnology - Gene-based Diagnostics and Therapeutic Interventions

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2)
Spanish; Castilian Elementary (A2) Elementary (A2) Beginner (A1) Elementary (A2)
Education
Degree Classification
2025/01/24 - 2029
Ongoing
Ph.D. in Pharmaceutical Sciences (Doutoramento)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2025/01/20 - 2025/01/31
Concluded
Advanced Course Principles and Practices in Drug Development (Curso de doutoramento (conclusão de unidades curriculares))
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
18
2025/01/13 - 2025/01/17
Concluded
Advanced course on Health Literacy (Curso de doutoramento (conclusão de unidades curriculares))
Universidade de Coimbra Faculdade de Farmácia, Portugal

Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
18
2025/01/13 - 2025/01/17
Attended
Advanced Course Mechanisms in Neuropsychiatric and Neurodegenerative Disorders (Curso de Especialização Tecnológica)
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2023/11/06 - 2024/02
Concluded
Training in Laboratory Animal Science Course (FELASA B) + DGAV (Direção-Geral da Alimentação e Veterinária) accreditation (Outros)
Major in Mouse and Rat
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

CNC.IBILI, Portugal
2017 - 2022
Concluded
Pharmaceutical Sciences (Mestrado integrado)
Universidade de Coimbra Faculdade de Farmácia, Portugal
"Terapia génica da doença de Huntington " (THESIS/DISSERTATION)
15
2022
Concluded
Hazardous Hospital Waste Management - Sorting and Packaging (Outros)
Ambiwaste, Portugal
2017/06
Concluded
Advanced Certificate in English (Outros)
Cambridge English Language Assessment Spain and Portugal, Spain
188- Grade C
2017
Concluded
Ciências e Tecnologias (Ensino secundário)
Escola Básica e Secundária Dr. Manuel Fernandes, Portugal
2015/07/28 - 2015/08/11
Concluded
Young Leaders: English Language and Leadership Programme (Outros)
Bucksmore Education, United Kingdom
2015/06
Concluded
First Certificate in English (Outros)
Cambridge English Language Assessment Spain and Portugal, Spain
170- Grade C
Affiliation

Science

Category
Host institution
Employer
2023/03 - Current Researcher (Research) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2022/05/09 - 2022/08/09 Research Trainee (Research) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Others

Category
Host institution
Employer
2022/10 - 2023/03 Voluntary Researcher Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2022/01 - 2022/05 Estagiária em Farmácia Comunitária Farmácia Mendes, Portugal
Farmácia Mendes, Portugal
2020/08 - 2020/08 Estagiária em Farmácia Comunitária Farmácia Mendes, Portugal
Farmácia Mendes, Portugal
Projects

Grant

Designation Funders
2023/09/01 - 2026/08/31 NEURODIET - Molecular Mechanisms of Dietary Intervention on Neurodegeneration (PT001)
JPND/0001/2022
Research Fellow
Universidade de Coimbra, Portugal

Universidade de Coimbra Instituto de Investigação Clínica e Biomédica de Coimbra, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2023/03 - 2023/12 Fighting Sars-CoV-2 with viral vectors
CENTRO-01-01D2-FEDER-000002
Research Fellow
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Comissão de Coordenação e Desenvolvimento Regional do Centro
Concluded
2023/01/01 - 2023/06/30 ReSet - Development of a food supplement based on Resveratrol for optimal CNS activity
CENTRO-01-0247-FEDER-070162
Research Fellow
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Comissão de Coordenação e Desenvolvimento Regional do Centro
Concluded
Outputs

Publications

Conference abstract
  1. Salgueiro, Ana Margarida Salgueiro; Ferreira-Marques, Marisa; Lopes, Sara; Pereira, Dina; Ribeiro, Rodrigo; Magda M Santana; Cavadas, Claudia; Pereira de Almeida, Luis. "Investigating Dietary Strategies in Machado-Joseph Disease Models". Paper presented in BEB Day 2025 - From micro-scales to macro-worlds: transcending the limits of science, Coimbra, 2025.
    Submitted
  2. Rufino-Ramos, David; Leandro, Kevin; Patricia R. Albuquerque; Vítor Carmona; Inês Martins; Rosário Faro; Henriques, Carina; et al. Corresponding author: Pereira de Almeida, Luis. "Extracellular vesicle-based delivery of silencing sequences for treatment of Machao-Joseph disease (MJD)/ Spinocerebellar Ataxia type-3 (SCA3)". Paper presented in 29th Congress of the European Society of Gene & Cell Therapy, Edinburgh, 2022.
    Published • 10.1089/hum.2022.29225.abstracts
  3. Leandro, Kevin; Rufino-Ramos, David; Tania D´Amelio; Salgueiro, Ana Margarida Salgueiro; Sara Lopes; Dina Pereira; Inês Martins; et al. Corresponding author: Pereira de Almeida, Luis. "Extracellular vesicles-mediated delivery of CRISPR/Cas9 systems to treat Machado-Joseph Disease". Paper presented in 29th Congress of the European Society for Gene and Cell Therapy (ESGCT) in collaboration with BSGCT; Edinburgh, Scotland, United Kingdom,, Edinburgh, 2022.
    Published • 10.1089/hum.2022.29225.abstracts
Conference poster
  1. Dina Pereira; Janete Cunha-Santos; Ana Vasconcelos-Ferreira; Joana Duarte-Neves; Isabel Onofre; Vítor Carmona; Célia A Aveleira; et al. Corresponding author: Dina Pereira. "Nuclear ageing in polyglutamine-induced neurodegeneration: a highlight on Machado-Joseph disease". Paper presented in International Congress for Ataxia Research 2024, 2024.
  2. Rufino-Ramos, David; Kevin Leandro; Patricia R. Albuquerque; Vitor Carmona; Inês M. Martins; Rosário Faro; Carina Henriques; et al. "Extracellular vesicle-based delivery of silencing sequences for treatment of Machao-Joseph disease (MJD)/ Spinocerebellar Ataxia type-3 (SCA3)". Paper presented in 29th Congress of the European Society of Gene & Cell Therapy, 2022.
  3. Leandro, Kevin; Rufino-Ramos, David; D'Amelio, T; Salgueiro, Ana Margarida Salgueiro; Lopes, Sara M.; Pereira, Dina; Martins, M; et al. ""Extracellular vesicles-mediated delivery of CRISPR/Cas9 systems to treat Machado-Joseph Disease".". Paper presented in 29th Congress of the European Society for Gene and Cell Therapy (ESGCT) in collaboration with BSGCT; Edinburgh, Scotland, United Kingdom,, 2022.
Preprint
  1. Salgueiro, Ana Margarida Salgueiro; Ferreira-Marques, Marisa; Rodrigo F.N. Ribeiro; Pereira, Dina; Costa, Daniela G.; Santana, Magda M; Lopes, Sara; Pereira de Almeida, Luis ; Cavadas, Claudia. Corresponding author: Cavadas, Claudia. "The Ketogenic Diet as a Therapeutic Strategy for Neurodegenerative Diseases: from Mechanisms of Action to Translational Challenges". 2025. https://doi.org/10.5281/zenodo.15215859.
    10.5281/zenodo.15215859
Thesis / Dissertation
  1. "Terapia génica da Doença de Huntington". Master, Universidade de Coimbra Faculdade de Farmácia, 2022. http://hdl.handle.net/10316/105549.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2024/11/25 Brain Health: How Diets Affect Neurodegenerative Diseases. Exploring the Ketogenic Diet, the Mediterranean Diet, and Caloric Restriction. Science and Technology Week
Colégio de São José - International School (Coimbra, Portugal)
2024/11/21 Super Foods for Super Brains! How Special Diets Can Help Keep Our Brain Strong. Science and Technology Week
Cantanhede Primary School (Coimbra, Portugal)
2022/09/26 Gene Therapy of Huntington's Disease Public examination for the conclusion of the Integrated Master's Degree in Pharmaceutical Sciences
Faculdade de Farmácia da Universidade de Coimbra (Coimbra, Portugal)

Event organisation

Event name
Type of event (Role)
Institution / Organization
2024/11/20 - 2024/11/20 Mini-Symposium, "Fundamental Research on Ageing: Why It Matters?” (2024/11/20 - 2024/11/20)
Symposium (Member of the Organising Committee)
Neuroendocrinology and Aging Group, Portugal

Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2023/10/10 - 2023/10/10 NEURODIET Consortium Meeting- Kick-off meeting of the project Neurodiet held in Coimbra, Portugal with the international partners. (2023/10/10 - 2023/10/10)
Meeting (Co-organisor)
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Event participation

Activity description
Type of event
Event name
Institution / Organization
2025/03/14 - 2025/03/16 HDYO International Young Adult Congress is a congress that brings together young people from all over the world who are affected by Huntington's disease.
Congress
HDYO´s International Young Adults Congress- Prague
Huntington's Disease Youth Organization, United Kingdom
2024/12/20 - 2024/12/20 This annual scientific event brings together researchers from diverse biomedical fields to foster interdisciplinary collaboration and showcase ongoing research at the University of Coimbra. The meeting includes keynote lectures, thematic sessions, and poster presentations focused on advancing biomedical knowledge and innovation.
Meeting
CIBB meeting
Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia, Portugal
2024/11/18 - 2024/11/24 Initiatives organized for the public, especially the younger ones, who will thus have the opportunity to get in touch with the scientific community and learn about some of the most recent research results in various scientific areas.
Other
Science and Technology Week
Ciência Viva, Portugal
2024/09/27 - 2024/09/27 The European Researchers' Night (NEI) is a Scientific Communication event that occurs annually in several European cities.This event aims to promote awareness and involvement of the scientific population, bringing researchers and civil society together. European Researchers' Night- Coimbra
Universidade de Coimbra, Portugal
2023/12/20 - 2023/12/20 The meeting brought together researchers, clinicians, and students from different scientific areas to present and discuss ongoing biomedical and translational research. The program included oral communications, poster sessions, and keynote lectures, fostering interdisciplinary dialogue and collaboration within the research community.
Meeting
CIBB meeting
Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia, Portugal
2023/03/17 - 2023/03/19 HDYO International Young Adult Congress is a congress that brings together young people from all over the world who are affected by Huntington's disease.
Congress
HDYO´s International Young Adults Congress- Glasgow
Huntington's Disease Youth Organization, United Kingdom
2019/09/28 - 2019/09/29 IV Congresso Nacional de Estudantes de Farmácia
Congress
Pelo teu futuro, Pelo futuro da Saúde
Associação Portuguesa de Estudantes de Farmácia, Portugal

Association member

Society Organization name Role
2025/03/27 - Current Huntigton Disease-Community Advisory Board (HD-CAB)- a global initiative representing the HD community, providing insights for research, clinical trials, and policy development to improve access to treatments. HD-CAB Team Member
2021 - Current Huntington's Disease Youth Organization Ambassador for HDYO with the aim of volunteering, raising awareness of HD and fundraising for HDYO.
2020 - Current Associação Portuguesa Dos Doentes De Huntington Member
2008 - 2015 Clube Náutico de Abrantes

Mentoring / Tutoring

Topic Student name
2024/04/15 - 2024/07/05 Pharmaceutical Science internship Daniela Trino
Distinctions

Award

2025 Travel Grant – HDYO International Young Adult Congress Prague 2025
Huntington's Disease Youth Organization, United Kingdom

Associação Portuguesa dos Doentes de Huntington, Portugal