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Ana Margarida Duarte Salgueiro completed her integrated master’s degree in Pharmaceutical Sciences in September 2022 from the Faculty of Pharmacy of the University of Coimbra. She wrote her master thesis entitled "Gene Therapy of Huntington's Disease", where she delved deeper into the different therapeutic approaches and strategies being developed in in the pre-clinical and clinical phases, with special emphasis on gene therapy strategies for Huntington's Disease and other polyglutamine diseases. The quality of the work was recognized with a mark of excellence (18 in 20). Motivated by the scientific curiosity and the relevance of the field of disorders with no treatment, she has been collaborating and working in the international recognized group led by Professor Luís Pereira de Almeida - group “Gene and Stem Cell Therapies” at the Center for Neuroscience and Cell Biology, University of Coimbra (CNC-UC). She started in this group with an internship as an undergraduate student and had the opportunity to participate in two funded projects in the context of Spinocerebellar ataxia type 3/Machado-Joseph Disease. This internship and her commitment, participation and interest in the research work was recognized as co-authorship in two communications (poster and an oral communication) presented at the international congress, 29th European Society of Gene and Cell Therapy Congress. During six months she was a Voluntary Researcher but more recently, since March 2023, she was granted with a competitive research fellowship to continue to do research work in the same group, always with big interest in Machado-Joseph Disease (MJD). Her growing interest in polyglutamine diseases and therapies in development led her to participate in the HDYO International Young Adult Congress in Glasgow, a congress that brings together young people from all over the world linked to Huntington's disease, and to join the Portuguese Association of Huntington's Patients, to better understand the highly debilitating reality of these genetic diseases. Learning and investigating more about these diseases is very closed to Margarida because she sees firsthand how debilitating these diseases are, since her father suffers from Huntington´s disease and she´s also at risk of having the same disease and she wants to be able to change that through the work she is doing and will do. She has an Advanced Certificate in English through the Cambridge English Language Assessment, which means she has a good command of the English language.
Identification

Personal identification

Full name
Ana Margarida Duarte Salgueiro

Citation names

  • Salgueiro, Ana Margarida Salgueiro

Author identifiers

Ciência ID
9C16-09F2-7174
ORCID iD
0000-0002-9713-3015

Email addresses

  • anasalgueiro99@gmail.com (Professional)
  • asalgueiro@cnc.uc.pt (Professional)
  • anasalgueiro99@hotmail.com (Personal)

Knowledge fields

  • Medical and Health Sciences - Health Sciences
  • Natural sciences - Biological Sciences - Cell Biology
  • Natural sciences - Biological Sciences - Molecular Biology
  • Natural sciences - Biological Sciences - Biology
  • Medical and Health Sciences - Medical Biotechnology - Health-Related Biotechnology
  • Medical and Health Sciences - Medical Biotechnology - Technologies Involving the Manipulation of Cells, Tissues, Organs or the Whole Organism
  • Medical and Health Sciences - Medical Biotechnology - Gene-based Diagnostics and Therapeutic Interventions

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2)
Spanish; Castilian Elementary (A2) Elementary (A2) Beginner (A1) Elementary (A2)
Education
Degree Classification
2023/11/06 - 2024/02
Concluded
Training in Laboratory Animal Science Course (FELASA B) + DGAV (Direção-Geral da Alimentação e Veterinária) accreditation (Outros)
Major in Mouse and Rat
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

CNC.IBILI, Portugal
2017 - 2022
Concluded
Pharmaceutical Sciences (Mestrado integrado)
Universidade de Coimbra Faculdade de Farmácia, Portugal
"Terapia génica da doença de Huntington " (THESIS/DISSERTATION)
15
2022
Concluded
Hazardous Hospital Waste Management - Sorting and Packaging (Outros)
Ambiwaste, Portugal
2017/06
Concluded
Advanced Certificate in English (Outros)
Cambridge English Language Assessment Spain and Portugal, Spain
188- Grade C
2017
Concluded
Ciências e Tecnologias (Ensino secundário)
Escola Básica e Secundária Dr. Manuel Fernandes, Portugal
2015/07/28 - 2015/08/11
Concluded
Young Leaders: English Language and Leadership Programme (Outros)
Bucksmore Education, United Kingdom
2015/06
Concluded
First Certificate in English (Outros)
Cambridge English Language Assessment Spain and Portugal, Spain
170- Grade C
Affiliation

Science

Category
Host institution
Employer
2023/03 - Current Researcher (Research) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2022/05/09 - 2022/08/09 Research Trainee (Research) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Others

Category
Host institution
Employer
2022/10 - 2023/03 Voluntary Researcher Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2022/01 - 2022/05 Estagiária em Farmácia Comunitária Farmácia Mendes, Portugal
Farmácia Mendes, Portugal
2020/08 - 2020/08 Estagiária em Farmácia Comunitária Farmácia Mendes, Portugal
Farmácia Mendes, Portugal
Projects

Grant

Designation Funders
2023/09/01 - 2026/08/31 NEURODIET - Molecular Mechanisms of Dietary Intervention on Neurodegeneration (PT001)
JPND/0001/2022
Research Fellow
Universidade de Coimbra, Portugal

Universidade de Coimbra Instituto de Investigação Clínica e Biomédica de Coimbra, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2023/03 - 2023/12 Fighting Sars-CoV-2 with viral vectors
CENTRO-01-01D2-FEDER-000002
Research Fellow
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Comissão de Coordenação e Desenvolvimento Regional do Centro
Concluded
2023/01/01 - 2023/06/30 ReSet - Development of a food supplement based on Resveratrol for optimal CNS activity
CENTRO-01-0247-FEDER-070162
Research Fellow
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Comissão de Coordenação e Desenvolvimento Regional do Centro
Concluded
Outputs

Publications

Conference poster
  1. Dina Pereira; Janete Cunha-Santos; Ana Vasconcelos-Ferreira; Joana Duarte-Neves; Isabel Onofre; Vítor Carmona; Célia A Aveleira; et al. Corresponding author: Dina Pereira. "Nuclear ageing in polyglutamine-induced neurodegeneration: a highlight on Machado-Joseph disease". Paper presented in International Congress for Ataxia Research 2024, 2024.
  2. Rufino-Ramos, David; Kevin Leandro; Patricia R. Albuquerque; Vitor Carmona; Inês M. Martins; Rosário Faro; Carina Henriques; et al. "Extracellular vesicle-based delivery of silencing sequences for treatment of Machao-Joseph disease (MJD)/ Spinocerebellar Ataxia type-3 (SCA3)". Paper presented in 29th Congress of the European Society of Gene & Cell Therapy, 2022.
  3. Leandro, Kevin; Rufino-Ramos, David; D'Amelio, T; Salgueiro, Ana Margarida Salgueiro; Lopes, Sara M.; Pereira, Dina; Martins, M; et al. ""Extracellular vesicles-mediated delivery of CRISPR/Cas9 systems to treat Machado-Joseph Disease".". Paper presented in 29th Congress of the European Society for Gene and Cell Therapy (ESGCT) in collaboration with BSGCT; Edinburgh, Scotland, United Kingdom,, 2022.
Thesis / Dissertation
  1. "Terapia génica da Doença de Huntington". Master, Universidade de Coimbra Faculdade de Farmácia, 2022. http://hdl.handle.net/10316/105549.
Activities

Event organisation

Event name
Type of event (Role)
Institution / Organization
2024/11/20 - 2024/11/20 Mini-Symposium, "Fundamental Research on Ageing: Why It Matters?” (2024/11/20 - 2024/11/20)
Symposium (Member of the Organising Committee)
Neuroendocrinology and Aging Group, Portugal

Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Event participation

Activity description
Type of event
Event name
Institution / Organization
2024/09/27 - 2024/09/27 The European Researchers' Night (NEI) is a Scientific Communication event that occurs annually in several European cities.This event aims to promote awareness and involvement of the scientific population, bringing researchers and civil society together. European Researchers' Night- Coimbra
Universidade de Coimbra, Portugal
2023/03/17 - 2023/03/19 HDYO´s International Young Adults Congress- Glasgow 2023
Congress
HDYO´s International Young Adults Congress
Huntington's Disease Youth Organization, United Kingdom
2019/09/28 - 2019/09/29 IV Congresso Nacional de Estudantes de Farmácia
Congress
Pelo teu futuro, Pelo futuro da Saúde
Associação Portuguesa de Estudantes de Farmácia, Portugal

Association member

Society Organization name Role
2021 - Current Huntington's Disease Youth Organization Ambassador
2020 - Current Associação Portuguesa Dos Doentes De Huntington Member
2008 - 2015 Clube Náutico de Abrantes

Mentoring / Tutoring

Topic Student name
2024/04/15 - 2024/07/05 Pharmaceutical Science internship Daniela Trino