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Identification

Personal identification

Full name
Carine Machado Gonçalves

Citation names

  • Gonçalves, Carine

Author identifiers

Ciência ID
9C1B-50D0-2A35
ORCID iD
0000-0002-4512-6147

Knowledge fields

  • Medical and Health Sciences - Basic Medicine - Immunology

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
German Beginner (A1) Beginner (A1) Beginner (A1) Beginner (A1)
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
French Intermediate (B1) Intermediate (B1) Intermediate (B1) Intermediate (B1)
Education
Degree Classification
2013/05/27
Concluded
 Ciências Biomédicas (Doutoramento)
Major in Sem especialidade
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
"Scavenger receptor cysteine-rich proteins on the cross-roads between innate and adaptive immunity" (THESIS/DISSERTATION)
 Unanimidade com distinçao
2013
Concluded
 n/a (Doutoramento)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
"Scavenger Receptor Cysteine-Rich proteins on the cross-roads between innate and adaptive immunity" (THESIS/DISSERTATION)
 Aprovado por unanimidade e distinção
2005
Concluded
 Biologia - ramo científico (Licenciatura)
Universidade de Évora, Portugal
"Clonagem e caraterização de um novo membro da superfamília de receptores scavenger ricos em cisteína (SRCR)" (THESIS/DISSERTATION)
 15
Affiliation

Science

Category
Host institution 		Employer
2019/01/01 - Current Research Assistant (Research) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2017/09/01 - Current Research Assistant (Research) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2017/09/01 - 2018/12/31 Postdoc (Research) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2016 - 2018 Postdoc (Research) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2016/07/01 - 2017/07/31 Postdoc (Research) Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2013 - 2013 Postdoc (Research) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2007/03/01 - 2008/02/15 Researcher (Research) Universidade do Minho, Portugal
2007 - 2008 Researcher (Research) Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal

Others

Category
Host institution 		Employer
2016/07/01 - 2017/06/30 PostDoc Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2013/07/15 - 2015/06/30 Post-doc Universidade do Minho, Portugal
2008/05/01 - 2013/05/01 PhD student Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2008/09/01 - 2009/07/31 Visiting Prof Simon Davis lab Weatherall Institute of Molecular Medicine - University of Oxford, United Kingdom
2006/04/01 - 2006/12/31 Estagio profissional IEFP Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2005/09/01 - 2006/03/31 voluntária em investigação Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2004/06/01 - 2005/06/01 Estagiário Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
Outputs

Publications

Journal article
  1. Alexandra G. Fraga; Katharina Roeltgen; Gabriela Trigo; Ramya K. Murthy; Shamim Akhtar; Madhavi Hebbur; Ana Rita Pacheco; et al. "Antimicrobial activity of Mycobacteriophage D29 Lysin B during Mycobacterium ulcerans infection". PLOS Neglected Tropical Diseases 13 8 (2019): e0007113-e0007113. https://doi.org/10.1371/journal.pntd.0007113.
    10.1371/journal.pntd.0007113
  2. Fraga, Alexandra G.; Branquinho, Gabriela Alexandra Trigo; Murthy, Ramya K.; Akhtar, Shamim; Hebbur, Madhavi; Pacheco, Ana Rita; Dominguez, Juan; et al. "Antimicrobial activity of Mycobacteriophage D29 Lysin B during Mycobacterium ulcerans infection". (2019): http://hdl.handle.net/1822/61425.
    10.1371/journal.pntd.0007113
  3. Gonçalves, Carine M.; Henriques, Sónia N.; Santos, Rita F.; Carmo, Alexandre M.. "CD6, a Rheostat-Type Signalosome That Tunes T Cell Activation". Frontiers in Immunology 9 (2018): http://dx.doi.org/10.3389/fimmu.2018.02994.
    Published • 10.3389/fimmu.2018.02994
  4. Miranda, Margarida Silva; Rodrigues, Márcia T.; Domingues, Rui Miguel Andrade; Costa, Rui R.; Paz, Elvira; Rodríguez-Abreu, Carlos; Freitas, Paulo; et al. "Development of Inhalable Superparamagnetic Iron Oxide Nanoparticles (SPIONs) in microparticulate system for antituberculosis drug delivery". (2018): http://hdl.handle.net/1822/58060.
    10.1002/adhm.201800124
  5. Silva JP; Gonçalves C; Costa C; Sousa J; Silva-Gomes R; Castro AG; Pedrosa J; Appelberg R; Gama FM. "Delivery of LLKKK18 loaded into self-assembling hyaluronic acid nanogel for tuberculosis treatment.". (2016): http://europepmc.org/abstract/med/27261333.
    10.1016/j.jconrel.2016.05.064
  6. Silva, João P.; Gonçalves, Carine; Costa, C.; Sousa, Jeremy; Silva-Gomes, Rita; Castro, António G.; Pedrosa, Jorge; Appelberg, Rui; Gama, F. M.. "Delivery of LLKKK18 loaded into self-assembling hyaluronic acid nanogel for tuberculosis treatment". (2016): http://hdl.handle.net/1822/41895.
    10.1016/j.jconrel.2016.05.064
  7. Silva-Gomes R; Marcq E; Trigo G; Gonçalves CM; Longatto-Filho A; Castro AG; Pedrosa J; Fraga AG. "Spontaneous Healing of Mycobacterium ulcerans Lesions in the Guinea Pig Model.". (2015): http://europepmc.org/abstract/med/26625302.
    10.1371/journal.pntd.0004265
  8. Gomes, Rita Silva; Marcq, Elly; Branquinho, Gabriela Alexandra Trigo; Gonçalves, Carine M.; Longatto Filho, Adhemar; Castro, António G.; Pedrosa, Jorge; Fraga, Alexandra G.. "Spontaneous healing of Mycobacterium ulcerans lesions in the guinea pig model". (2015): http://hdl.handle.net/1822/40101.
    10.1371/journal.pntd.0004265
  9. Oliveira, M.I.; Gonçalves, C.M.; Pinto, M.; Fabre, S.; Santos, A.M.; Lee, S.F.; Castro, M.A.A.; et al. "CD6 attenuates early and late signaling events, setting thresholds for T-cell activation". European Journal of Immunology 42 1 (2012): 195-205. http://www.scopus.com/inward/record.url?eid=2-s2.0-84855225261&partnerID=MN8TOARS.
    10.1002/eji.201040528
  10. James, J.R.; McColl, J.; Oliveira, M.I.; Dunne, P.D.; Huang, E.; Jansson, A.; Nilsson, P.; et al. "The T cell receptor triggering apparatus is composed of monovalent or monomeric proteins". Journal of Biological Chemistry 286 37 (2011): 31993-32001. http://www.scopus.com/inward/record.url?eid=2-s2.0-80052730531&partnerID=MN8TOARS.
    10.1074/jbc.M111.219212
  11. Bamberger, M.; Santos, A.M.; Gonçalves, C.M.; Oliveira, M.I.; James, J.R.; Moreira, A.; Lozano, F.; Davis, S.J.; Carmo, A.M.. "A new pathway of CD5 glycoprotein-mediated T cell inhibition dependent on inhibitory phosphorylation of fyn kinase". Journal of Biological Chemistry 286 35 (2011): 30324-30336. http://www.scopus.com/inward/record.url?eid=2-s2.0-80052235105&partnerID=MN8TOARS.
    10.1074/jbc.M111.230102
  12. Gonçalves, C.M.; Castro, M.A.A.; Henriques, T.; Oliveira, M.I.; Pinheiro, H.C.; Oliveira, C.; Sreenu, V.B.; et al. "Molecular cloning and analysis of SSc5D, a new member of the scavenger receptor cysteine-rich superfamily". Molecular Immunology 46 13 (2009): 2585-2596. http://www.scopus.com/inward/record.url?eid=2-s2.0-67650569240&partnerID=MN8TOARS.
    10.1016/j.molimm.2009.05.006
  13. Nunes, R.J.; Castro, M.A.A.; Gonçalves, C.M.; Bamberger, M.; Pereira, C.F.; Bismuth, G.; Carmo, A.M.. "Protein interactions between CD2 and Lck are required for the lipid raft distribution of CD2". Journal of Immunology 180 2 (2008): 988-997. http://www.scopus.com/inward/record.url?eid=2-s2.0-40449133966&partnerID=MN8TOARS.
Thesis / Dissertation
  1. Carine Machado Gonçalves. "Scavenger receptor cysteine-rich proteins on the cross-roads between innate and adaptive immunity". PhD, 2013. https://repositorio-aberto.up.pt/handle/10216/73821.

Other

Other output
  1. Antimicrobial activity of Mycobacteriophage D29 Lysin B during Mycobacterium ulcerans infection. 2018. Alexandra G. Fraga; Gabriela Trigo; Juan Dominguez; Rita Silva-Gomes; Carine M. Gonçalves; Hugo Oliveira; António G. Castro; Joana Azeredo; Jorge Pedrosa. https://doi.org/10.1101/507129.
    10.1101/507129
Distinctions

Other distinction

2014 Grant of the ICVS/3B's Associate Laboratory
Universidade do Minho, Portugal
2011 EMBO conference award for young scientists
2008 PhD fellowship
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2003 Bolsa de Erasmus
Universidade de Évora, Portugal