Identification
Personal identification
- Full name
- Maria Joana Pinto Desterro
Citation names
- Desterro, Joana
Author identifiers
- Ciência ID
- 9E11-7F4C-67F4
- ORCID iD
- 0000-0002-6359-7233
- Scopus Author Id
- 6602949583
Email addresses
- jdesterro@ipolisboa.min-saude.pt (Professional)
- joanadesterro@gmail.com (Personal)
Addresses
- Instituto Português de Oncologia de Lisboa Francisco Gentil, Rua Prof Lima Basto, 1099-023, Lisboa, Lisboa, Portugal (Professional)
Knowledge fields
- Medical and Health Sciences - Clinical Medicine - Hematology
- Natural sciences - Biological Sciences - Cell Biology
- Natural sciences - Biological Sciences - Molecular Biology
Languages
Language | Speaking | Reading | Writing | Listening | Peer-review |
---|---|---|---|---|---|
English | Advanced (C1) | Advanced (C1) | Advanced (C1) | Advanced (C1) | |
Spanish; Castilian | Intermediate (B1) | Advanced (C1) | Beginner (A1) | Intermediate (B1) | |
French | Beginner (A1) | Intermediate (B1) | Beginner (A1) | Beginner (A1) |
Education
Degree | Classification | |
---|---|---|
2014/01/01 - 2019
Concluded
|
Hematologia Clínica (Título de especialista)
Instituto Português de Oncologia de Lisboa Francisco Gentil EPE, Portugal
|
19,17 |
2006 - 2012/06/01
Concluded
|
Estudos Básicos de Medicina (Mestrado integrado)
Universidade de Lisboa Faculdade de Medicina, Portugal
"Mestrado Integrado em Medicina" (THESIS/DISSERTATION)
|
16 |
1996 - 1999/10/30
Concluded
|
Biochemistry (Doctor of Philosophy)
University of St Andrews, United Kingdom
"Role of SUMO-1 modification in transcriptional activation" (THESIS/DISSERTATION)
|
n/a |
1989 - 1994/12/01
Concluded
|
Engenharia Química - Biotecnologia (Licenciatura)
Universidade de Lisboa Instituto Superior Técnico, Portugal
"n/a" (THESIS/DISSERTATION)
|
16 |
Affiliation
Science
Category Host institution |
Employer | |
---|---|---|
2004 - Current | Researcher (Research) | Instituto de Medicina Molecular João Lobo Antunes, Portugal |
Instituto de Medicina Molecular João Lobo Antunes, Portugal |
Teaching in Higher Education
Category Host institution |
Employer | |
---|---|---|
2014/01/01 - Current | Invited Assistant Professor (University Teacher) | Universidade de Lisboa Faculdade de Medicina, Portugal |
Universidade de Lisboa Faculdade de Medicina, Portugal | ||
2003/09/30 - 2014/01/01 | Assistant Professor (University Teacher) | Universidade de Lisboa Faculdade de Medicina, Portugal |
Other Careers
Category Host institution |
Employer | |
---|---|---|
2020 - Current | Assistente (Médica) | Instituto Português de Oncologia de Lisboa Francisco Gentil EPE, Portugal |
Instituto Português de Oncologia de Lisboa Francisco Gentil EPE, Portugal | ||
2014/01/01 - 2019/10/24 | Interno (Médica) | Instituto Português de Oncologia de Lisboa Francisco Gentil EPE, Portugal |
Instituto Português de Oncologia de Lisboa Francisco Gentil EPE, Portugal | ||
2013/01/01 - 2013/12/31 | Interno (Médica) | Centro Hospitalar Universitário Lisboa Norte EPE, Portugal |
Centro Hospitalar Universitário Lisboa Norte EPE, Portugal |
Positions / Appointments
Category Host institution |
Employer | |
---|---|---|
2021/08/01 - Current | Coordenadora do Laboratório de Hemato - oncologia | Instituto Português de Oncologia de Lisboa Francisco Gentil EPE, Portugal |
Others
Category Host institution |
Employer | |
---|---|---|
2002/09/30 - 2003/09/30 | EC Post-Doctoral Fellow | Universidade de Lisboa Faculdade de Medicina, Portugal |
2000/09/30 - 2002/09/30 | EMBO Post-Doctoral Fellow | Universidade de Lisboa Faculdade de Medicina, Portugal |
1999/10/01 - 2000/09/01 | BBRSC Post-Doctoral Fellow | University of St Andrews Biomedical Sciences Research Complex, United Kingdom |
1996/01/01 - 1999/10/01 | Ph.D. Student | University of St Andrews, United Kingdom |
1995/01/01 - 1995/12/30 | Research Technician | Instituto Nacional de Saúde Doutor Ricardo Jorge, Portugal |
Projects
Grant
Designation | Funders | |
---|---|---|
2011/11 - 2014/04 | Oncobiology: developing educational tools for a new generation of physician-scientists | Fundação para a Ciência e a Tecnologia, I.P. |
2008/09 - 2008/12 | Is microRNA-mediated translational repression involved in auto-regulation of heterodimeric splicing factor U2AF?
ASTF 400-2008
Post-doc Fellow
Friedrich Miescher Institute for Biomedical Research, Switzerland
|
European Molecular Biology Laboratory
Concluded
|
2000/09 - 2002/09 | Dynamics of splicing factors
ALTF 239-2000
Post-doc Fellow
Instituto de Medicina Molecular João Lobo Antunes, Portugal
|
European Molecular Biology Laboratory
Concluded
|
1996 - 1999 | Role of SUMO modification in Transcription activation
PRAXIS XXI/BD/ 9240 /96
PhD Student Fellow
University of St Andrews Biomedical Sciences Research Complex, United Kingdom
|
Fundação para a Ciência e a Tecnologia
Concluded
|
Contract
Designation | Funders | |
---|---|---|
2018/10/01 - 2021/09/30 | Diffuse Large B-cell lymphoma blood based proteome signatures
PTDC/BTM-TEC/30087/2017
Researcher
Universidade Nova de Lisboa, Portugal
|
Fundação para a Ciência e a Tecnologia
Ongoing
|
2018/10/01 - 2021/09/30 | Targeting Intra-Tumor Heterogeneity as a promising therapeutic strategy for cancer
PTDC/MED-ONC/28660/2017
Researcher
Associação para a Inovação e Desenvolvimento da FCT, Portugal
Instituto de Medicina Molecular João Lobo Antunes, Portugal |
Fundação para a Ciência e a Tecnologia
Ongoing
|
2018/01/01 - 2019/12/31 | Characteristics and frequency of IDH mutations and how they associate with other known mutations in myeloid cancer genes in
real world AML patients in Portugal
PTDC/MED-FAR/4692/2020
Researcher
Instituto de Medicina Molecular João Lobo Antunes, Portugal
|
Celgene Portugal
Concluded
|
2016/07/01 - 2019/12/31 | Novel tumorigenic mechanisms of aberrant epigenetic regulation in clear cell renal cell carcinoma
PTDC/BIM-ONC/0016/2014
Researcher
Instituto de Medicina Molecular João Lobo Antunes, Portugal
|
Fundação para a Ciência e a Tecnologia
Concluded
|
2013/06/01 - 2015/11/30 | SETD2 mediates a novel tumor suppressor mechanism that is misregulated in clear cell renal carcinoma
PTDC/BIM-ONC/0384/2012
Researcher
Instituto de Medicina Molecular João Lobo Antunes, Portugal
|
Fundação para a Ciência e a Tecnologia
Concluded
|
2011/11/01 - 2014/04/30 | Oncobiology: developing educational tools for a new generation of physician-scientists
HMSP-PCM/0007/2010
Principal investigator
Instituto de Medicina Molecular João Lobo Antunes, Portugal
Centro Hospitalar Universitário Lisboa Norte EPE, Portugal |
Fundação para a Ciência e a Tecnologia
Concluded
|
2011/02/01 - 2014/01/31 | Splicing-coupled mechanisms of chromatin remodeling and their global role in transcription
PTDC/BIA-BCM/111451/2009
Researcher
Instituto de Medicina Molecular João Lobo Antunes, Portugal
|
Fundação para a Ciência e a Tecnologia
Concluded
|
2007/01 - 2008/06 | Regulation of mRNA processing and transport within the nucleus
Researcher
|
Fundação para a Ciência e a Tecnologia, I.P. |
2007/01 - 2008/03 | Expression and Function of Ubiquitin Conjugating Enzyme hsUbc6e
Researcher
|
Fundação para a Ciência e a Tecnologia, I.P. |
2005/07/01 - 2007/06/30 | Regulation of mRNA processing and transport within the nucleus
POCI/SAU-MMO/57700/2004
Researcher
Instituto de Medicina Molecular João Lobo Antunes, Portugal
|
Fundação para a Ciência e a Tecnologia
Concluded
|
2005/04/01 - 2007/06/30 | Expression and Function of Ubiquitin Conjugating Enzyme hsUbc6e
POCI/SAU-MMO/61129/2004
Researcher
Instituto de Medicina Molecular João Lobo Antunes, Portugal
|
Fundação para a Ciência e a Tecnologia
Concluded
|
Outputs
Publications
Journal article |
|
Thesis / Dissertation |
|
Activities
Supervision
Thesis Title Role |
Degree Subject (Type) Institution / Organization |
|
---|---|---|
2017 - 2018 | Identification of novel potential therapeutic targets for T-cell acute lymphoblastic leukaemia.
Supervisor
|
Estudos Básicos de Medicina (Master)
Universidade de Lisboa Faculdade de Medicina, Portugal
|
Jury of academic degree
Topic Role |
Candidate name (Type of degree) Institution / Organization |
|
---|---|---|
2019 | Identification of novel potential therapeutic targets for T-cell acute lymphoblastic leukaemia
Supervisor
|
Catarina Sofia Micaelo Fernandes (Master)
Universidade de Lisboa Faculdade de Medicina, Portugal
|
2012 | The role of mRNA translation on nonsense-mediated decay inhibition of transcripts carrying a short open reading frame
Thesis Member
|
Isabel Cristina Ramos Peixeiro (PhD)
Universidade de Lisboa Faculdade de Ciências, Portugal
|
Association member
Society Organization name | Role | |
---|---|---|
2014 - Current | Sociedade Portuguesa de Hematologia | Membro |
2014 - Current | European Haematology Association | Member |
Conference scientific committee
Conference name | Conference host | |
---|---|---|
2018 - 2018 | 23rd Congress of the European Hematology Association (EHA) | Estocolmo, Suécia |
Consulting
Activity description | Institution / Organization | |
---|---|---|
2017 - Current | Participation as co-investigator in Phase II and Phase III Multicenter, Randomized Double Blind, Placebo Controlled Clinical Trials to Evaluate Drugs in the Treatment of Myelodysplastic and Myeloproliferative syndromes; Acute and Chronic Leukemia. Principal Investigator: Francesca Pierdomenico, MD and António Medina de Almeida, MD/PhD. | Instituto Português de Oncologia de Lisboa Francisco Gentil EPE, Portugal |
2015 - 2016 | Technical-scientific consultancy in the pedagogical games component Project “Vivências de Ciência na pré-graduação em Medicina” Programa GAPIC (Gabinete de Apoio à Investigação Científica, Tecnológica e Inovação) PI: Prof. Doutor João Ferreira. | Universidade de Lisboa Faculdade de Medicina, Portugal |
Course / Discipline taught
Academic session | Degree Subject (Type) | Institution / Organization | |
---|---|---|---|
2009 - Current | Oncobiology (Tronco Comum V.a) Oncobiologia) | Estudos Básicos de Medicina (Licenciatura) | Universidade de Lisboa Faculdade de Medicina, Portugal |
2007 - Current | Molecular Biology of the Cell (Módulo I.I - Biologia Molecular, Celular e do Desenvolvimento Humano e Genética) | Estudos Básicos de Medicina (Licenciatura) | Universidade de Lisboa Faculdade de Medicina, Portugal |
2012 - 2017 | Molecular Biology and Gene Expression | Oncobiologia (Mestrado integrado) | Universidade de Lisboa Faculdade de Medicina, Portugal |
Mentoring / Tutoring
Topic | Student name | |
---|---|---|
2014 - 2018 | Co-transcriptional quality control of mRNA biogeneis: impact for human genetic diseases | Rita Catarina Vaz Drago |
2011 - 2015 | Effects of Chemotherapy and radiotherapy in rectal cancer: significance of different cellular outcomes in tumour behavior | Joana Maria Tato Ribeiro da Costa |
Other jury / evaluation
Activity description | Institution / Organization | |
---|---|---|
2018 - Current | Reviewer of abstracts submitted to the 23rd Congress of the European Hematology Association (EHA) “Myelodysplastic syndromes – Biology & Translational Research” | |
2016 - 2018 | Book reviewer for W.W. Norton & Company Ltd. : Case Studies in Cancer. https://www.wwnorton.co.uk/books/9780393679519-case-studies-in-cancer |