Filipa Alexandra Gomes Calisto (A019-37CE-102C)

Curriculum Vitae

I am an integrative biochemist with a solid biophysical and microbiology background. I have a bachelor’s degree in Genetics (2009) from Universidade Trás-os-Montes e Alto Douro and a master’s degree in Microbiology (2011) from FCUL. My master’s work was developed at the Research Institute for Medicines iMed.ULisboa, where I investigated the role of carbapenemases in bacterial clinical isolates and contributed to the understanding of the mechanisms of bacterial antibiotic resistance and dissemination in a public hospital, Hospital Santa Maria, a work described in 2 publications. I completed my PhD in Biochemistry (2019) at ITQB-Universidade NOVA de Lisboa. The work, reported in 5 articles, provided a groundbreaking contribution to the study of bioenergetics, particularly on ACIII (co-first authors: Sousa, Calisto etal 2018 Nat Commun IF=14.9). In September 2019, I started my post-doctoral work on the energy transduction mechanisms of respiratory proteins at BioISI/FCUL, reported in 5 articles. My extensive knowledge of respiratory membrane proteins allowed me to provide a revolutionary view on biological mechanisms for energy transduction (Calisto etal 2021 Chem Rev IF=72.1). I am the author (h-index 7, GoogleScholar) of 11 peer-reviewed articles in international journals (7 as first author, all in Q1 journals), which collected >230 citations. I delivered 5 oral presentations and contributed to 8 proceedings and >15 posters at international meetings. I am/was a member of 5 FCT projects and PI and Co-PI of 2 BioISI projects.

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Identification

Personal identification

Full name: Filipa Alexandra Gomes Calisto

Citation names

Calisto, Filipa

Author identifiers

Ciência ID: A019-37CE-102C

Email addresses

facalisto@fc.ul.pt (Professional)

Addresses

Campus da Faculdade de Ciências da Universidade de Lisboa, C8 Lab 8.4.56, 1749-016, Campo Grande, Lisboa, Portugal (Professional)

Knowledge fields

Natural sciences - Biological Sciences
Natural sciences - Biological Sciences - Biochemistry
Natural sciences - Biological Sciences - Molecular Biology
Natural sciences - Biological Sciences - Microbiology
Natural sciences - Biological Sciences - Biophysics

Languages

Language	Speaking	Reading	Writing	Listening	Peer-review
Portuguese (Mother tongue)
English	Upper intermediate (B2)	Upper intermediate (B2)	Upper intermediate (B2)	Upper intermediate (B2)	Upper intermediate (B2)

Affiliation

Science

	Category Host institution	Employer
2019/09/16 - Current	Postdoc (Research)	Universidade de Lisboa Instituto de Biossistemas e Ciências Integrativas, Portugal

Projects

Grant

	Designation	Funders
2022/07/04 - Current	Exploring respiratory proteins from human bacterial pathogens PTDC/BIA-BQM/2599/2021 Post-doc Fellow Universidade de Lisboa Instituto de Biossistemas e Ciências Integrativas, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2015/07/01 - 2019/07/22	A molecular insight into the respiratory alternative complex III SFRH/BD/104481/2014 PhD Student Fellow Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2008/10/01 - 2009/05/31	Analysis of variance and use of software PTDC/AGR-GPL/65876/2006 Scientific Initiation Fellow Universidade de Trás-os-Montes e Alto Douro, Portugal	Fundação para a Ciência e a Tecnologia Concluded

Contract

	Designation	Funders
2019/09/15 - 2022/06/15	Unraveling structure and function determinants in Alternative Complex III PTDC/BIA-BQM/30528/2017 Post-doc Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2012/07/01 - 2015/06/30	A molecular insight into the respiratory alternative complex III Provided by PTCRIS: 120949 Research Fellow	Fundação para a Ciência e a Tecnologia

Other

	Designation	Funders
2023/02/01 - 2023/12/31	Toward the discovery of new drugs against multidrug-resistant bacterial pathogens 000 Principal investigator Universidade de Lisboa Instituto de Biossistemas e Ciências Integrativas, Portugal	Universidade de Lisboa Instituto de Biossistemas e Ciências Integrativas Concluded
2022/05/09 - 2023/04/30	Biochemical characterization of a serine protease involved in grapevine defense towards biotic stresses 08 Co-Principal Investigator (Co-PI) Universidade de Lisboa Instituto de Biossistemas e Ciências Integrativas, Portugal	Universidade de Lisboa Instituto de Biossistemas e Ciências Integrativas Ongoing

Outputs

Publications

Book chapter	Calisto, F.; Refojo, P.N.; Pereira, M.M.. "Bioenergetics theory and components: Respiratory alternative complex III - Structural and functional insights". 143-149. 2021.
Conference poster	Calisto, Filipa; Graf, Simone; Ballmoos, Christoph von; Pereira, Manuela M.. Corresponding author: Pereira, Manuela M.. "Ion-translocation by the respiratory Alternative Complex III". Paper presented in 21st edition of the European BioEnergetics Conference, 2022. https://doi.org/10.1016/j.bbabio.2023.148983
Journal article	Calisto, Filipa; Todorovic, Smilja; Louro, Ricardo O.; Pereira, Manuela M.. "Exploring substrate interaction in respiratory alternative complex III from Rhodothermus marinus". Biochimica et Biophysica Acta (BBA) - Bioenergetics (2023): 148983. http://dx.doi.org/10.1016/j.bbabio.2023.148983. 10.1016/j.bbabio.2023.148983 Calisto, Filipa; Pereira, Manuela M.. "Modularity of membrane-bound charge-translocating protein complexes". Biochemical Society Transactions 49 6 (2021): 2669-2685. http://dx.doi.org/10.1042/bst20210462. Published • 10.1042/bst20210462 Calisto, Filipa; Pereira, Manuela M.. "The Ion-Translocating NrfD-Like Subunit of Energy-Transducing Membrane Complexes". Frontiers in Chemistry 9 (2021): http://dx.doi.org/10.3389/fchem.2021.663706. Open access • Published • 10.3389/fchem.2021.663706 Calisto, Filipa; Cátia Caneiras; Sofia Cerqueira; Luis Lito; José Melo-Cristino; Aida Duarte. "Klebsiella pneumoniae Producing Carbapenemase KPC-3 Identified In Hospital Wards". Revista Portuguesa de Doenças Infecciosas (2012): Published
Thesis / Dissertation	"Emergência de Carbapenemases em Klebsiella pneumoniae: o desafio de bactérias multirresistentes e virulentas". Master, Universidade de Lisboa Faculdade de Ciências, 2012.

Activities

Supervision

	Thesis Title Role	Degree Subject (Type) Institution / Organization
2022/09/01 - Current	Investigation of Quinone Reductases from Pseudomonas aeruginosa Supervisor	Human Biology (Master) Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal

Jury of academic degree

	Topic Role	Candidate name (Type of degree) Institution / Organization
2021/02/14	Mechanisms of protein dysfunction in aminoacyl-tRNA synthetase related to neurological diseases (Thesis) Main arguer	Diogo Ferreira (Master) Universidade de Lisboa Faculdade de Ciências, Portugal

Association member

	Society Organization name	Role
2019/01/01 - 2022/12/31	Sustainable Plate project coordinator Since 2019 I have been coordinating the Sustainable Plate, funded by ProVeg International. I coordinated and supervised several training courses on vegetarian cuisine aimed at collective catering.	Co-coordinator

Course / Discipline taught

	Academic session	Degree Subject (Type)	Institution / Organization
2020/10 - Current	Assisting practical classes at the Recombinant proteins module from the masters on Biochemistry.	Biochemistry (Mestrado)	Universidade de Lisboa Faculdade de Ciências, Portugal

Mentoring / Tutoring

	Topic	Student name
2023/01/02 - Current	Internship	Andreia Gomes
2023/01 - Current	Internship	Miguel Trigo
2022/09 - Current	Internship	Margarida Silva
2021/09/01 - 2022/06/30	Internship	Andreia Bispo
2021/09/01 - 2022/06/30	Internship	Simão Caracho
2022/02/01 - 2022/03/31	ERAMUS + Respiratory membrane proteins in pathogenic bacteria	Emilia Wassiljew
2018/06/01 - 2018/07/31	Internship	Afonso Pais

Scientific expedition

	Activity description	Institution / Organization
2023/02/04 - 2033/03/06	Short Term Scientific Mission - COST Action CA21145 \| I have worked for 1 month at Dr Janet Vonck' laboratory from Prof Werner Kühlbrandt group at Max-Planck-Institute fur Biophysics-Frankfurt (Germany, 2023), where I learned cryo-electron microscopy sample preparation and data processing.	Max-Planck-Institut für Biophysik, Germany

Distinctions

Award

2023	Short Term Scientific Mission Grant (COST Action CA21145) European Cooperation in Science and Technology, Belgium
2021	American Chemical Society's (ACS) Editors' Choice "Mechanisms of Energy Transduction by Charge Translocating Membrane Proteins" ACS Publications, United States
2019	Short Term Scientific Mission Grant (COST Action CA15203) European Cooperation in Science and Technology, Belgium
2018	Short Term Scientific Mission Grant (COST Action CA15203) European Cooperation in Science and Technology, Belgium
2016	Short Term Scientific Mission Grant (COST Action CM1306) European Cooperation in Science and Technology, Belgium
2016	EBSA Bursary European Biophysical Societies' Association, Portugal
2015	Research grant for doctoral degree Fundação para a Ciência e a Tecnologia, Portugal
2009	Scientific Initiation Fellow Fundação para a Ciência e a Tecnologia, Portugal