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Bruna Alexandra Vale Araújo graduated in Biochemistry from the School of Sciences at the University of Minho in July 2017, and she completed a master's degree in Health Sciences at the Life and Health Sciences Research Institute (ICVS), School of Medicine at the University of Minho, in October 2019. In her master's dissertation, she unveiled a neuroanatomical description and challenged the current knowledge on the structural plasticity of adult hilar cytogenesis. With this work, she received an award for a best poster presentation. During this time, she contributed to four scientific publications. For the following nine months, she worked in a spin-off company at Behavioral and Molecular lab (Bn'ML). She investigates pharmacological strategies for Parkinson's Disease treatment under the supervision of Dr. Fábio Teixeira. In addition, she co-authored a book chapter and a review. Currently, she was accepted in a doctoral programme of Biomedicine, Faculty of Medicine, and she was awarded with a FCT grant to explore the impact of the deletion of hippocampal cytogenesis on a Parkinson's Disease model at Institute for Research and Innovation in Health (i3S).
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Identification

Personal identification

Full name
Bruna Alexandra Vale Araújo

Citation names

  • Araújo, Bruna

Author identifiers

Ciência ID
A116-BAA0-3360
ORCID iD
0000-0002-7365-0077

Email addresses

  • up202002061@up.pt (Professional)
  • bruna2araujo@gmail.com (Personal)

Knowledge fields

  • Medical and Health Sciences - Basic Medicine - Neurosciences
  • Medical and Health Sciences - Health Sciences
  • Natural sciences - Biological Sciences - Biochemistry

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Intermediate (B1) Intermediate (B1) Intermediate (B1) Intermediate (B1)
Education
Degree Classification
2023/01/01 - 2027
Ongoing
 FCT Grant (Doutoramento)
Major in Neurosciences
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Universidade do Porto Faculdade de Medicina, Portugal
2022/09/09 - 2026
Ongoing
 Doctoral Programme in Biomedicine (Doutoramento)
Universidade do Porto Faculdade de Medicina, Portugal
2023/12/04 - 2023/12/05
Concluded
 Workshop on Scientific Writing: How to streamline the process of writing a scientific paper (Outros)
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2023/11/06 - 2023/11/08
Concluded
 3D microscopy imaging with clearness | 1st edition (Outros)
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2023/06 - 2023/06
Concluded
 The safety and effectiveness of Magnetic Resonance guided Focused Ultrasound (MRgFUS) in a Parkinson’s Disease preclinical model (Outros)
Commissariat à l'Énergie Atomique et aux Énergies Alternatives NeuroSpin, France
 18
2022/09/26 - 2022/09/30
Concluded
 Introduction to Digital BioImage Analysis - 4th edition (Outros)
Major in Microscopy
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2021/04/15 - 2022/04/14
Concluded
 Research Grant: "SynChronize - Focused Ultrasound combined with Stem Cells Secretome and Pharmacotherapies: establishing a Multimodal path for Parkinson's Disease repair." (Outros)
Major in Health Sciences
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2020/05/04 - 2020/05/06
Concluded
 Introduction to data analysis and image processing with Matlab course (Outros)
Major in Bioinformatic; Neurosciences
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
 Approved
2017/09/01 - 2019/10/21
Concluded
 Health Sciences (Mestrado)
Major in Neurosciences
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
"Hilar hippocampal cytogenesis: a new source of neural plasticity in the adult mammalian brain?" (THESIS/DISSERTATION)
 18
2018/05/02 - 2018/05/18
Concluded
 Advanced training: Nano-bioengeneering for Medicine (Outros)
Major in Nanotechnology
International Iberian Nanotechnology Laboratory, Portugal

Universidade do Minho, Portugal
16
2018/03 - 2018/05
Concluded
 Laboratory Rotation (Outros)
Major in Lung Injury, Fibrosis
Universidade do Minho, Portugal

Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
16
2018/01/29 - 2018/03/09
Concluded
 Course of Laboratory Animal Science (Outros)
Major in Animals Science
Universidade do Minho, Portugal

Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
16
2014/09/08 - 2017/07/10
Concluded
 Biochemistry (Licenciatura)
Major in Ciências Exatas
Universidade do Minho, Portugal

Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
"Glial Plasticity as a key mechanism in the recurrent model of depression." (THESIS/DISSERTATION)
 15
Affiliation

Teaching in Higher Education

Category
Host institution 		Employer
2023/09/25 - 2024/07/31 Invited Assistant (Polytechnic Teacher) Instituto Politecnico do Porto Escola Superior de Tecnologia da Saúde do Porto, Portugal
Instituto Politecnico do Porto Escola Superior de Tecnologia da Saúde do Porto, Portugal

Others

Category
Host institution 		Employer
2024/06/03 - 2024/06/21 Early Career Training Programme Internship Medizinische Universität Wien Institut für Pharmakologie, Austria
Medizinische Universität Wien Institut für Pharmakologie, Austria
2023/05/08 - 2023/08/10 Internship Commissariat à l'Énergie Atomique et aux Énergies Alternatives NeuroSpin, France
Commissariat à l'Énergie Atomique et aux Énergies Alternatives NeuroSpin, France
2019/12/16 - 2020/09/16 Professional internship BnML Behavioral and Molecular Lab Lda, Portugal
BnML Behavioral and Molecular Lab Lda, Portugal
Projects

Other

Designation Funders
2022 - Current Conectividade hipocampal e desempenho comportamental na saúde e na depressão: qual o papel da astrogliogénese adulta?
2022.02201.PTDC
Researcher
Universidade do Minho, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
Outputs

Publications

Book chapter
  1. Araújo, Bruna; Caridade-Silva, Rita; Domingues, Helena Sofia (1D14-1122-F41A); Salgado, António José (7A1F-809B-EC3F); Teixeira, Fábio Gabriel (7D14-5AA0-450A). "Mesenchymal Stem Cell Secretome: A Potential Biopharmaceutical Component to Regenerative Medicine?". In Handbook of Stem Cell, edited by Prof Kh H Haider. Portugal: Springer Nature, 2022.
    Published • 10.1007/978-981-16-6016-0_46-1
  2. Bruna Araújo; Rita Caridade Silva; Sofia Domingues; António J. Salgado; Fábio G. Teixeira. "Mesenchymal Stem Cell Secretome: A Potential Biopharmaceutical Component to Regenerative Medicine". 2022.
    10.1007/978-981-19-2655-6_46
Book review
  1. Araújo, Bruna; Caridade-Silva, Rita; Soares-Guedes, Carla ; Martins-Macedo, Joana; Eduardo Gomes; Susana Monteiro; Teixeira, Fábio G. "Neuroinflammation and Parkinson's Disease from neurodegeneration to therapeutic opportunities". (2022):
    Published
Conference abstract
  1. Caridade-Silva, Rita; Araújo, Bruna; Campos, Jonas; Domingues, Helena S.; Salgado, António José (7A1F-809B-EC3F); Teixeira, Fábio Gabriel (7D14-5AA0-450A). "N-acetylcysteine as a Parkinson's disease therapy: creating a strategy for disease modeling and repair". Paper presented in International conference on Alzheimer's and Parkinson's Disease and related neurological disorders, Barcelona, 2022.
Conference poster
  1. Araújo, Bruna; Caridade-Silva, Rita; Svenningsson, Per; Pinto, Luisa; Teixeira, Fábio Gabriel (7D14-5AA0-450A). "Impact of Abrogation of Adult Hippocampal Cytogenesis on Parkinson's Disease Pre-clinical Model". Paper presented in International Conference on Alzheimer's and Parkinson's Diseases and related neurological disorders 2024, 2024.
  2. Araújo, Bruna; Caridade-Silva, Rita; Svenningsson, Per; Luísa Pinto (6718-2ED6-30B6); Fábio G. Teixeira. "Modulation of Adult Hippocampal Neurogenesis by Antidepressants May Aid the Prevention of Parkinson’s Disease". Paper presented in Brilliant PhDs, brighter future: Shaping Science together! (PhDay 2023), 2023.
  3. Caridade-Silva, Rita; Araújo, Bruna; Hugo JR Fernandes; Wade-Martins, Richard; Teixeira, Fábio G. "Repurposing Multimodal Strategies for Parkinson¿s Disease: Creating the Path for Disease Delay and Repair?". Paper presented in Brilliant PhDs, brighter future: Shaping Science together! (PhDay 2023), 2023.
  4. Araújo, Bruna; Joana Catarina Martins Macedo; Silveira-Rosa, Tiago; Patrícia Carvalho Patrício; Loureiro-Campos, Eduardo; Caridade-Silva, Rita; Teixeira, Fábio Gabriel; et al. "Hilus, a new cytogenic hippocampal niche modulated by stress exposure and treatment with antidepressants". Paper presented in 11th IBRO - World Congress of Neuroscience 2023, 2023.
  5. Araújo, Bruna; Campos, Jonas; Caridade-Silva, Rita; Mendes-Pinheiro, Bárbara; Marques, Cláudia Raquel ; Barata-Antunes, Sandra; Lima, Rui; et al. "Modulation of Brain Connectivity, Structure, and Motor Function by Safinamide Multimodal Actions in a Pre-clinical Model of Parkinson’s Disease". Paper presented in 11th IBRO - World Congress of Neuroscience 2023, 2023.
  6. Caridade-Silva, Rita; Araújo, Bruna; Martins-Macedo, Joana; Larrat, Benoit; Meriaux, Sebastien; Teixeira, Fábio G. "Impact of N-acetylcysteine on Parkinson's Disease Functional Connectomics: A Friend or Foe?". Paper presented in 11th IBRO World Congress of Neuroscience 2023, 2023.
  7. Araújo, Bruna; Campos, Jonas; Caridade-Silva, Rita; Mendes-Pinheiro, Bárbara; Marques, Cláudia Raquel ; Barata-Antunes, Sandra; Rui Augusto Ribeiro Lima; et al. "Modulation of Brain Structure and Motor Function by Safinamide Multimodal Actions in a Pre-clinical Model of Parkinson’s Disease". Paper presented in FENS Regional Meeting 2023, 2023.
  8. Araújo, Bruna; Campos, Jonas; Domingues, Helena Sofia (1D14-1122-F41A); Silva, Rita Caridade ; Mendes-Pinheiro, Bárbara; Marques, Cláudia Raquel ; Barata-Antunes, Sandra; et al. "Addressing the Impact of Safinamide as a Parkinson's Disease Neuroprotective Drug". Paper presented in International conference on Alzheimer's and Parkinson's Disease and related neurological disorders (2022), 2022.
  9. Araújo, Bruna (A116-BAA0-3360); Caridade-Silva, Rita; Magalhães, Ricardo; Larrat, Benoit; Meriaux, Sebastien; Pêgo, Ana Paula; Teixeira, Fábio Gabriel (7D14-5AA0-450A). "Targetting Parkinson's Disease Brain Affected Areas by the local delivery of multimodal pharmacological strategies". Paper presented in European Neuroscience Conference by Doctoral Students (ENCODS), 2021.
  10. Caridade-Silva, Rita; Araújo, Bruna; Campos, Jonas; Domingues, Helena S.; Salgado, António José (7A1F-809B-EC3F); Teixeira, Fábio Gabriel (7D14-5AA0-450A). "Combining Stem Cells Secretome and N-acetylcysteine to Parkinson's Disease modeling and repair.". Paper presented in European Neuroscience Conference by Doctoral Students (ENCODS), 2021.
  11. Araújo, Bruna; Silveira-Rosa, Tiago; Joana Catarina Martins Macedo; Loureiro-Campos, Eduardo (EF11-B5BA-1D82); Patrício, Patrícia (BD10-ECC3-1C6E); Sousa, Nuno; Mateus-Pinheiro, António; Pinto, Luisa. "Revisiting Neurogenesis in the Adult Mammalian Brain Unveiling Hilar Neurogenesis". Paper presented in VI AEICBAS Biomedical Congress, 2019.
Journal article
  1. Vilela, Cristiana; Araújo, Bruna; Soares-Guedes, Carla; Caridade-Silva, Rita; Martins-Macedo, Joana; Teixeira, Catarina; Gomes, Eduardo D.; et al. "From the Gut to the Brain: Is Microbiota a New Paradigm in Parkinson’s Disease Treatment?". Cells 13 9 (2024): 770. http://dx.doi.org/10.3390/cells13090770.
    10.3390/cells13090770
  2. Martins-Macedo, Joana; Araújo, Bruna; Anjo, Sandra I.; Silveira-Rosa, Tiago; Patrício, Patrícia; Alves, Nuno Dinis; Silva, Joana M.; et al. "Glial-restricted precursors stimulate endogenous cytogenesis and effectively recover emotional deficits in a model of cytogenesis ablation". Molecular Psychiatry (2024): http://dx.doi.org/10.1038/s41380-024-02490-z.
    10.1038/s41380-024-02490-z
  3. Caridade-Silva, Rita; Araújo, Bruna; Martins-Macedo, Joana; Teixeira, Fábio G.. "N-Acetylcysteine Treatment May Compensate Motor Impairments through Dopaminergic Transmission Modulation in a Striatal 6-Hydroxydopamine Parkinson’s Disease Rat Model". Antioxidants 12 6 (2023): 1257. http://dx.doi.org/10.3390/antiox12061257.
    10.3390/antiox12061257
  4. Bruna Araújo; Rita Caridade-Silva; Guedes, C.; Joana Martins-Macedo; Eduardo Gomes; Susana Monteiro; Fábio Teixeira. "Neuroinflammation and Parkinson’s Disease—From Neurodegeneration to Therapeutic Opportunities". Cells (2022): http://dx.doi.org/10.3390/cells11182908.
    10.3390/cells11182908
  5. Machado-Santos, Ana R.; Loureiro-Campos, Eduardo; Patrício, Patrícia; Araújo, Bruna; Alves, Nuno Dinis; Mateus-Pinheiro, António; Correia, Joana Sofia; et al. "Beyond New Neurons in the Adult Hippocampus: Imipramine Acts as a Pro-Astrogliogenic Factor and Rescues Cognitive Impairments Induced by Stress Exposure". Cells 11 3 (2022): 390. http://dx.doi.org/10.3390/cells11030390.
    Published • 10.3390/cells11030390
  6. Silveira-Rosa, Tiago; Mateus-Pinheiro, António; Correia, Joana Sofia; Silva, Joana Margarida; Martins-Macedo, Joana; Araújo, Bruna; Machado-Santos, Ana Rita; et al. "Suppression of adult cytogenesis in the rat brain leads to sex-differentiated disruption of the HPA axis activity". Cell Proliferation 55 2 (2021): http://dx.doi.org/10.1111/cpr.13165.
    Published • 10.1111/cpr.13165
  7. Mateus-Pinheiro, António; Patrício, Patrícia; Alves, Nuno Dinis; Martins-Macedo, Joana; Caetano, Inês; Silveira-Rosa, Tiago; Araújo, Bruna; et al. "Hippocampal cytogenesis abrogation impairs inter-regional communication between the hippocampus and prefrontal cortex and promotes the time-dependent manifestation of emotional and cognitive deficits". Molecular Psychiatry (2021): http://dx.doi.org/10.1038/s41380-021-01287-8.
    10.1038/s41380-021-01287-8
  8. Machado-Santos, Ana R.; Alves, Nuno D.; Araújo, Bruna; Correia, Joana S.; Patrício, Patrícia; Mateus-Pinheiro, António; Loureiro-Campos, Eduardo; et al. "Astrocytic plasticity at the dorsal dentate gyrus on an animal model of recurrent depression". Neuroscience 454 (2021): 94-104. http://dx.doi.org/10.1016/j.neuroscience.2019.10.032.
    10.1016/j.neuroscience.2019.10.032
Activities

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2024/04/05 - 2024/04/05 8th Symposium of the Portuguese Glial Network
Symposium
 8th Symposium of the Portuguese Glial Network
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2023/09/09 - 2023/09/13 Scientific Poster Presentation on 11th IBRO - IBRO World Congress of Neuroscience 2023
Congress
 IBRO 2023 - IBRO World Congress of Neuroscience
Sociedad Española de Neurociencia, Spain

International Brain Research Organization, France
2023/05/03 - 2023/05/05 Scientific Poster Presentation on FENS Regional Meeting 2023
Congress
 FENS Regional Meeting 2023
Federation of European Neuroscience Societies, Belgium
2022/03/16 - 2022/03/20 Scientific Poster Presentation on International conference on Alzheimer's and Parkinson's Disease and related neurological disorders (AD/PD 2022)
Congress
 International conference on Alzheimer's and Parkinson's Disease and related neurological disorders (2022)
2021/06/04 - 2021/06/06 Scientific Poster presentation at European Neuroscience Conference by Doctoral Students (ENCODS)
Congress
 European Neuroscience Conference by Doctoral Students (ENCODS)
Federation of European Neuroscience Societies, Belgium
2019/05/30 - 2019/06/01 XVI Meeting of the Portuguese Society for Neuroscience Annual congress (Portugal) in the neuroscience field
Congress
 XVI Meeting of the Portuguese Society for Neuroscience
Sociedade Portuguesa de Neurociências, Portugal
2019/05/29 - 2019/05/29 IV Symposium of Portuguese Glial Network Portuguese meeting about glial cells.
Symposium
 IV Symposium of Portuguese Glial Network
2019/03/15 - 2019/03/18 VII AEICBAS Biomedical Congress. Congress organized the Institute of Biomedical Science Abel Salazar by students and for students.
Congress
 VI AEICBAS Biomedical Congress
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2019/03/15 - 2019/03/16 Scientific Poster presentation at VII AEICBAS Biomedical Congress
Congress
 VII AEICBAS Biomedical Congress
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2018/03/15 - 2018/03/18 VI AEICBAS Biomedical Congress. Congress organized the Institute of Biomedical Science Abel Salazar by students and for students.
Congress
 VI AEICBAS Biomedical Congress
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2016/03/18 - 2016/03/21 IX National Meeting of Biochemistry Students National meeting between biochemistry' student which allow sharing knowledge between student from different cities in Portugal, but also with speakers.
Meeting
 IX National Meeting of Biochemistry Students
Universidade de Coimbra, Portugal

Association member

Society Organization name Role
2019 - Current Society for Neuroscience (SPN) Member

Committee member

Activity description
Role 		Institution / Organization
2017/04/07 - 2017/04/10 X National Meeting of Biochemistry Students National meeting between biochemistry' student which allow sharing knowledge between student from different cities in Portugal, but also with speakers.
President / Vice-president
 Universidade do Minho, Portugal
2016/04/05 - 2016/04/06 VII Biochemistry Meeting Biochemistry meeting organized by student and for students in University of Minho, School of Sciences
Member
 Universidade do Minho, Portugal

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2024 - Current Biochemistry, Degree in Health Products and Food Supplements, ESS/P.Porto Biochemistry (Curso Técnico Superior Profissional) Instituto Politecnico do Porto Escola Superior de Tecnologia da Saúde do Porto, Portugal
2024 - Current Biochemistry, Degree in Cultures and Laboratoty Maintenance Degree, ESS/P.Porto Biochemistry (Curso Técnico Superior Profissional) Instituto Politecnico do Porto Escola Superior de Tecnologia da Saúde do Porto, Portugal
2024 - Current Biochemistry, Pharmacy degree, ESS/P.Porto Biochemistry (Licenciatura) Instituto Politecnico do Porto Escola Superior de Tecnologia da Saúde do Porto, Portugal
2023/09 - Current Applied Biochemistry, Degree in Radioactive Material in a Biomedical Context, ESS|P.Porto Applied Biochemistry (Curso Técnico Superior Profissional) Instituto Politecnico do Porto Escola Superior de Tecnologia da Saúde do Porto, Portugal
Distinctions

Award

2024 SPN travel grant
Sociedade Portuguesa de Neurociências, Portugal
2019 Scientific Poster Presentation
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal