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Andreia Sofia Bernardo. Published 15 articles in journals. Works in the area(s) of Natural sciences with emphasis on Biological Sciences with emphasis on Molecular Biology. In his curriculum Ciência Vitae the most frequent terms in the context of scientific, technological and artistic-cultural output are: cardiomyocyte progenitors; soluble growth factor; embryonic stem cells; EGF; mesoderm; heart development ; pluripotency; .
Identification

Personal identification

Full name
Andreia Sofia Bernardo

Citation names

  • Bernardo, Andreia Sofia

Author identifiers

Ciência ID
A213-318C-0C31
ORCID iD
0000-0002-5355-6657

Telephones

Telephone
  • (0044) 2037960639 (Professional)

Knowledge fields

  • Natural sciences - Biological Sciences - Developmental Biology

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2)
Education
Degree Classification
2004/09 - 2008/12
Concluded
 PhD (Doutoramento)
Major in Developmental and Molecular Biology
University of Aberdeen, United Kingdom
"The role of the transcription factor PDX1 in mouse stem cell differentiation towards pancreas." (THESIS/DISSERTATION)
1999/09 - 2004/07
Concluded
 Biology (Licenciatura)
Major in Scientific, Developmental Biology
Faculty of Sciences, University of Lisbon , Portugal
"Characterisation of pancreatic Nestin expressing cells, possible progenitors of the islets of Langerhans " (THESIS/DISSERTATION)
 16
Affiliation

Science

Category
Host institution 		Employer
2020/02/01 - Current Visiting Researcher (Research) Imperial College London - Imperial Centre for Translational and Experimental Medicine, United Kingdom
Imperial College London - Imperial Centre for Translational and Experimental Medicine, United Kingdom
2018/09 - Current Postdoc (Research) The Francis Crick Institute, United Kingdom
2016/11 - 2018/07 Postdoc (Research) University of Cambridge, United Kingdom
The Francis Crick Institute, United Kingdom
2012/09 - 2016/11 Postdoc (Research) University of Cambridge, United Kingdom
National Institute of Medical Research (NIMR), United Kingdom
2008 - 2012 Postdoc (Research) University of Cambridge, United Kingdom
University of Cambridge, United Kingdom
Projects

Grant

Designation Funders
2019/03 - 2024/03 Left ventricle cardiomyocytes: their emergence, identity and maturation
210987/Z/18/Z
 Wellcome Trust
2012/10 - 2018/07 Molecular determinants underpinning development of human pluripotent stem cells into cardiomyocytes
BHF-FS/12/37/29516
 British Heart Foundation
2012/01 - 2015/12 Study the new role Ccbe1 growth factor in creating heart tissue starting ES cell
Provided by PTCRIS: 121095
 Fundação para a Ciência e a Tecnologia, I.P.
Outputs

Publications

Journal article
  1. Bernardo, Andreia. "Allele-specific RNA-seq expression profiling of imprinted genes in mouse isogenic pluripotent states.". Epigenetics & Chromatin (2019): https://europepmc.org/articles/PMC6376749.
    10.1186/s13072-019-0259-8
  2. Andreia S. Bernardo; Alice Jouneau; Hendrik Marks; Philip Kensche; Julianna Kobolak; Kristine Freude; Vanessa Hall; et al. "Mammalian embryo comparison identifies novel pluripotency genes associated with the naïve or primed state". Biology Open (2018): bio.033282-bio.033282. https://doi.org/10.1242/bio.033282.
    10.1242/bio.033282
  3. Bernardo, Andreia. "Distinctive Roles of Canonical and Noncanonical Wnt Signaling in Human Embryonic Cardiomyocyte Development.". Stem cell reports (2016): http://europepmc.org/abstract/med/27641648.
    10.1016/j.stemcr.2016.08.008
  4. Bernardo, Andreia. "Brachyury and SMAD signalling collaboratively orchestrate distinct mesoderm and endoderm gene regulatory networks in differentiating human embryonic stem cells.". Development (Cambridge, England) (2015): http://europepmc.org/abstract/med/26015544.
    10.1242/dev.117838
  5. Bernardo, Andreia. "Stable methylation at promoters distinguishes epiblast stem cells from embryonic stem cells and the in vivo epiblasts.". Stem cells and development (2014): http://europepmc.org/abstract/med/24738887.
    10.1089/scd.2013.0639
  6. Bernardo, Andreia. "Differentiation of trophoblast cells from human embryonic stem cells: to be or not to be?". Reproduction (Cambridge, England) (2014): http://europepmc.org/abstract/med/24518070.
    10.1530/rep-14-0080
  7. Bernardo, Andreia. "Directed differentiation of embryonic origin-specific vascular smooth muscle subtypes from human pluripotent stem cells.". Nature protocols (2014): http://europepmc.org/abstract/med/24675733.
    10.1038/nprot.2014.059
  8. Bernardo, Andreia. "Generation of human vascular smooth muscle subtypes provides insight into embryological origin-dependent disease susceptibility.". Nature biotechnology (2012): http://europepmc.org/abstract/med/22252507.
    10.1038/nbt.2107
  9. Bernardo, Andreia. "BRACHYURY and CDX2 mediate BMP-induced differentiation of human and mouse pluripotent stem cells into embryonic and extraembryonic lineages.". Cell stem cell (2011): http://europepmc.org/abstract/med/21816365.
    10.1016/j.stem.2011.06.015
  10. Bernardo, Andreia. "Biphasic induction of Pdx1 in mouse and human embryonic stem cells can mimic development of pancreatic beta-cells.". Stem cells (Dayton, Ohio) (2009): http://europepmc.org/abstract/med/19056911.
    10.1634/stemcells.2008-0310
  11. Bernardo, Andreia. "Pancreatic transcription factors and their role in the birth, life and survival of the pancreatic beta cell.". Molecular and cellular endocrinology (2008): http://europepmc.org/abstract/med/18687378.
    10.1016/j.mce.2008.07.006
  12. Bernardo, Andreia. "Stem cells and metabolic diseases.". Biochemical Society transactions (2008): http://europepmc.org/abstract/med/18481959.
    10.1042/bst0360363
  13. Bernardo, Andreia. "Embryonic stem cell therapy for diabetes mellitus.". Seminars in cell & developmental biology (2007): http://europepmc.org/abstract/med/17959396.
    10.1016/j.semcdb.2007.09.009
  14. Bernardo, Andreia. "Presence of endocrine and exocrine markers in EGFP-positive cells from the developing pancreas of a nestin/EGFP mouse.". Molecular and cellular endocrinology (2006): http://europepmc.org/abstract/med/16698177.
    10.1016/j.mce.2006.03.003
  15. Bernardo, Andreia. "Purification and Characterization of a Population of EGFP-Expressing Cells from the Developing Pancreas of a Neurogenin3/EGFP Transgenic Mouse.". Organogenesis (2005): http://europepmc.org/abstract/med/19521525.
    10.4161/org.2.1.1727

Intellectual property

Patent
  1. Bernardo, Andreia Sofia. 2021. "Population of cells comprising an increased proportion of left ventricular cardiomyocytes and uses thereof.". United Kingdom.
    Pending
  2. Bernardo, Andreia Sofia. 2015. "Populations of smooth muscle cells of specific embryonic lineages". United Kingdom.
    Withdrawn