Ana Raquel Costa Brito (A216-6315-E1E6)

Curriculum Vitae

Ana Raquel Costa Brito

Ana Raquel Costa Brito is a Ph.D. in Biomedicine by the University da Beira Interior. From October 2014 until April 2015 she was the holder of a Research Fellowship in the field of Immunology in the same Institution. Over that period she acquired experience in flow cytometry technique and in the isolation/establishment of primary cultures of human peripheral blood mononuclear cells. Later she was the recipient of a Fundação para a Ciência e a Tecnologia Ph.D. studentship in the field of Basic Neurobiology at the Health Sciences Research Centre (CICS-UBI) where she investigated the rat choroid plexus as a source of peptides with neurogenesis induction potential. During that period she acquired vast experience in several Molecular Biology techniques (Nucleic acid/ Protein extraction, RT-PCR, Real-time quantitative PCR and Western blot), and in other laboratory techniques such as sterile cell culture, immunohistochemical and immunofluorescence techniques and microscopy. She is currently a Research Technician at the Polytechnic of Guarda (IPG) in the health, well-being, and related healthcare technologies field.

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Identification

Personal identification

Full name: Ana Raquel Costa Brito

Citation names

Costa-Brito, Ana R.

Author identifiers

Ciência ID: A216-6315-E1E6
ORCID iD: 0000-0003-0507-0991

Knowledge fields

Natural sciences - Biological Sciences - Biology
Natural sciences - Biological Sciences - Cell Biology
Natural sciences - Biological Sciences - Molecular Biology
Medical and Health Sciences - Basic Medicine - Neurosciences

Languages

Language	Speaking	Reading	Writing	Listening	Peer-review
English	Upper intermediate (B2)	Upper intermediate (B2)	Upper intermediate (B2)	Upper intermediate (B2)	Upper intermediate (B2)

Education

	Degree	Classification
2022/10/03 - 2023/11/07 Concluded	Team Management - Building Happy Teams (Outros) Universidade da Beira Interior, Portugal	20
2017/09/01 - 2023/02/15 Concluded	Biomedicine (Doutoramento) Major in Neurosciences Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal "The Choroid Plexus as a source and target of Prolactin in the brain" (THESIS/DISSERTATION)	Approved with Distinction
2022/10/15 - 2022/12/18 Concluded	Mobility and Active Ageing McTivAgeing Edition 2023 Online course (Outros) Universidade de Lisboa Faculdade de Motricidade Humana, Portugal
2022/04/06 - 2022/06/23 Concluded	Blockchain Technology (Outros) Instituto Politécnico da Guarda, Portugal
2022/04/01 - 2022/04/30 Concluded	Go4Training "Programa Digital de Capacitação para a Prevenção da Sarcopenia, Fragilidade e Quedas" (Outros) Universidade de Lisboa Faculdade de Motricidade Humana, Portugal	100%
2021/03/18 - 2021/03/20 Concluded	Models of the Blood-Brain Barrier: Scientific Tools to Target the Brain (Outros) Universidade de Lisboa Faculdade de Farmácia, Portugal
2019/10/07 - 2019/11/11 Concluded	Adobe Illustrator (Outros) Universidade da Beira Interior, Portugal
2019/05/21 - 2019/05/24 Concluded	In Vitro Models of Biological Barriers for Health Sciences Apllications (Outros) Universidade do Porto Faculdade de Farmácia, Portugal
2018/10/01 - 2018/11/19 Concluded	Curso para el desempeño de las funciones B, C y D en roedores, lagomorfos, carnívoros, cerdos e pequeños ruminantes - Animal Experimentation (Outros) Centro de Cirugía de Mínima Invasión Jesús Usón, Spain
2018/09/24 - 2018/09/28 Concluded	IV Quantitative Fluorescence Microscopy Course (Outros) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2015/10/02 - 2016/07/31 Concluded	Integrated Management Systems (Environment, Quality, Safety and Social Responsibility) (Pós-Graduação) Instituto Politécnico da Guarda Escola Superior de Tecnologia e Gestão, Portugal	17
2016/05/20 - 2016/06/18 Concluded	Integrated Management Systems - Internal Auditor Course (ISO 9001, ISO 14001, OHSAS 18001) (Outros) Instituto Politécnico da Guarda Escola Superior de Tecnologia e Gestão, Portugal SGS Portugal S.A., Portugal	16
2015/09/07 - 2016/03/14 Concluded	Technician of Information and Communication Systems (Curso de Especialização Tecnológica) Universidade da Beira Interior, Portugal
2012/09/17 - 2014/11/10 Concluded	Biomedical Sciences (Mestrado) Universidade da Beira Interior, Portugal "Phenotypic and Functional Aspects of Lymphocyte Populations in Patients with Blood Dyscrasias Undergoing Phlebotomy" (THESIS/DISSERTATION)	18
2009/09/14 - 2012/07/12 Concluded	Biomedical Sciences (Licenciatura) Universidade da Beira Interior, Portugal	15

Affiliation

Science

	Category Host institution	Employer
2022/01/10 - Current	Research Assistant (Research)	Instituto Politécnico da Guarda, Portugal
	Instituto Politécnico da Guarda Unidade de Investigação para o Desenvolvimento do Interior, Portugal
2017/09/01 - 2023/02/15	Researcher (Research)	Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal

2014/10/01 - 2015/04/15	Researcher (Research)	Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal

Others

	Category Host institution	Employer
2017/03/13 - 2017/08/25	Internship	STEMLAB, S.A:, Portugal

2015/12/08 - 2016/03/04	Internship	Altran Portugal S.A., Portugal

Projects

Grant

	Designation	Funders
2024/01/01 - Current	SER65+: Ações multissectoriais integradas para Suporte ao Envelhecimento Saudável e Resiliente 0289_SER65_PLUS_6_P Researcher Instituto Politécnico da Guarda, Portugal Fundación para la Formación e Investigación de los Profesionales de la Salud de Extremadura, Spain Cluster Sociosanitario de Extremadura, Spain Centro de Cirugía de Mínima Invasión Jesús Usón, Spain Centro para a Economia e Inovação Social, Portugal Innovation Services SA, Portugal Comunidade Intermunicipal das Beiras e Serra da Estrela, Portugal Universidad de Extremadura, Spain Unidade Local de Saúde da Guarda EPE, Portugal
2023/12/01 - Current	LiterAGE4All: Fostering e-inclusion to improve digital health literacy and healthy ageing in adults 50+ 2023-1-PT01-KA220-ADU-000165655 Researcher Instituto Politécnico da Guarda, Portugal Centro de Cirugía de Mínima Invasión Jesús Usón, Spain Stiftung Digitale Chancen Foundation, Germany Politechnika Slaska, Poland Sociedade Portuguesa de Literacia em Saúde, Portugal
2022/03/01 - 2024/06/30	Improving competences of older people caregivers towards Healthy Ageing through digital transformation (EducAGE) 2021-1-PT01-KA220-ADU-000028254 Researcher Instituto Politécnico da Guarda, Portugal Centro de Cirugía de Mínima Invasión Jesús Usón, Spain Univerzita Hradec Králové, Czech Republic Semmelweis Egyetem, Hungary Univerzita Karlova Lékarská fakulta v Hradci Králové, Czech Republic	Erasmus Plus Ongoing
2023/01/01 - 2023/12/31	REcuperar doentes com condição pós-COVID-19 através do ExeRcício (RECOVER) 17860 Researcher Instituto Politécnico da Guarda, Portugal	Ongoing
2022/09/01 - 2023/08/31	Modelo de acción para el despliegue de tecnologías innovadoras enfocadas a la promoción del envejecimiento activo en la región EuroACE (EuroAGE2) 0770_EuroAGE2_4_E Researcher Instituto Politécnico da Guarda, Portugal Centro de Cirugía de Mínima Invasión Jesús Usón, Spain Instituto Politécnico de Castelo Branco, Portugal Universidad de Extremadura Escuela Politécnica, Spain	Concluded
2017/09 - 2021/12/31	Is the choroid plexus an alternative source of prolactin to the central nervous system? Impact on neurogenesis SFRH/BD/121890/2016 COVID/BD/151831/2021 PhD Student Fellow Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2014/10/01 - 2015/04/15	Hormonal and Inflammatory Basis of Age-Related Diseases CENTRO-07-ST24-FEDER-002015-HIB-1-007 Research Fellow Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal	Programa Operacional Regional do Centro 2007-2013 QREN - Programa "Mais Centro" Concluded

Other

	Designation	Funders
2020/10/01 - 2021/04/30	Effects of prolactin on rat choroid plexus transcriptome “Concurso interno para apoio a projetos na área da bioinformática", Project Centro-01-0145-FEDER-000019—C4—Centro de Competências em Cloud Computing Researcher Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal C4 – Cloud Computing Competence Centre, Universidade da Beira Interior, Portugal	Concluded

Outputs

Publications

Conference abstract	Costa-Brito, Ana R.; Bovolini, A; Ana Lopes; Diogo Chouzal; Marques, Ermelinda; Tracana, Rosa Branca; Juan Francisco Ortega-Morán; et al. "Informal caregivers as promotors of Healthy Ageing: Developing a blended course". Paper presented in AGEING CONGRESS, Leiria, 2023. Published
Conference poster	Rúa-Alonso, María; Pires, Nuno; Marques, Miguel; Bovolini, A; Vaz, Cláudia; Costa-Brito, Ana R.; Serra, Nuno; Carolina Vila-Chã. "Effect of ageing on ankle muscle strength and standing postural control". Paper presented in II International Congress on Resistance Training Optimisation and Neuromuscular Performance, 2023. Costa-Brito, Ana R.; Bovolini, A; Ana Lopes; Diogo Chouzal; Marques, Ermelinda; Tracana, Rosa Branca; Juan Francisco Ortega-Morán; et al. "Developing a "Digital White Paper" for empowering caregivers training". Paper presented in 3rd International Congress Health and Well-being Intervention (ICHWBI), 2023. Bovolini, A; Rúa-Alonso, María; Costa-Brito, Ana R.; Carolina Vila-Chã. "Age- and sex-related differences on muscle strength of the tibiotarsal joint and its association with physical and functional fitness". Paper presented in 28th Annual Congress of the European College of Sport Science (ECSS), 2023. Carolina Vila-Chã; Bovolini, A; Rúa-Alonso, María; Costa-Brito, Ana R.. "Acute effects of a static and a neuromuscular proprioceptive facilitation stretching protocol on different strength profiles". Paper presented in 28th Annual Congress of the European College of Sport Science (ECSS), 2023. Rúa-Alonso, María; Bovolini, A; Costa-Brito, Ana R.; Carolina Vila-Chã. "Treino de potência muscular em idosos: Projeto PowerAGE". Paper presented in 3rd International Congress of Health and Well-being Intervention, 2023. Costa-Brito, Ana R.; Quintela, Telma; Isabel Maria Theriaga Mendes Varanda Gonçalves; Duarte, Ana Catarina; Ana Raquel Ferreira da Costa; Furtado, André; José Eduardo Cavaco; Lemos, Manuel C; SANTOS, Cecilia R A. "Secreted frizzled-related protein 2: Another choroid plexus-derived peptide with neurogenic potential". Paper presented in XVII International CICS-UBI Symposium, 2022. Costa-Brito, Ana R.; Bovolini, JA; Ana Lopes; Diogo Chouzal; Marques, Ermelinda; Tracana, Rosa Branca; Juan Francisco Ortega Morán ; et al. Corresponding author: Carolina Vila-Chã. "EducAGE - Improving competences of older people caregivers towards healthy ageing through digital transformation". Paper presented in XVII International CICS-UBI Symposium, 2022. Costa-Brito, Ana R.; Quintela, Telma; Gonçalves, Isabel; Duarte, Ana Catarina; Costa, Ana Raquel; Cavaco, Jose; Lemos, Manuel Carlos; SANTOS, Cecilia R A. "Expression of Prolactin in the Choroid Plexus: An alternative source of Prolactin in the rat Brain". Paper presented in FENS 2020 Virtual Forum, 2020. Costa-Brito, Ana R.; Telma Quintela; Isabel Gonçalves; Ana Catarina Duarte; Ana Raquel Costa; José Eduardo Cavaco; Lemos, Manuel Carlos; Cecília Reis Alves Santos. "Expression of prolactin and Prolactin Receptor in the Choroid Plexus". Paper presented in III International Congress in Health Sciences Research Trends in Aging and Cancer, 2019. Costa-Brito, Ana R.; Telma Quintela; Isabel Gonçalves. "Choroid Plexus: An alternative source of Prolactin to the Central Nervous System?". Paper presented in XIII Annual CICS Symposium, 2018. Costa-Brito, Ana R.; Cardoso, Elsa Maria; Martinez, Jorge; Arosa, Fernando A.. "Anomalies in NK and B cells in erythrocytosis patients". Paper presented in IX Annual CICS Symposium, 2014.
Journal article	Ana Raquel Costa-Brito; Antonio Bovolini; María Rúa-Alonso; Cláudia Vaz; Juan Francisco Ortega-Morán; J. Blas Pagador; Carolina Vila-Chã. "Home-based exercise interventions delivered by technology in older adults: A scoping review of technological tools usage". International Journal of Medical Informatics (2024): http://dx.doi.org/10.1016/j.ijmedinf.2023.105287. 10.1016/j.ijmedinf.2023.105287 María Rúa-Alonso; Antonio Bovolini; Ana Raquel Costa-Brito; Cláudia Vaz; Ermelinda Marques; Nuno Serra; Vítor P. Lopes; Carolina Vila-Chã. "Exploring Perceived Barriers to Physical Activity among Older Adults Living in Low-Population Density Regions: Gender Differences and Associations with Activity Dimensions". Healthcare (2023): https://doi.org/10.3390/healthcare11222948. 10.3390/healthcare11222948 Carolina Vila-Chã; Antonio Bovolini; Cristiana Francisco; Ana R. Costa-Brito; Cláudia Vaz; María Rua-Alonso; José Antonio de Paz; Taian Vieira; Goncalo V. Mendonca. "Acute effects of isotonic eccentric exercise on the neuromuscular function of knee extensors vary according to the motor task: impact on muscle strength profiles, proprioception and balance". Frontiers in Sports and Active Living (2023): http://dx.doi.org/10.3389/fspor.2023.1273152. 10.3389/fspor.2023.1273152 Ana R. Costa; Ana C. Duarte; Ana R. Costa-Brito; Isabel Gonçalves; Cecília R.A. Santos. "Bitter taste signaling in cancer". Life Sciences 315 (2023): 121363-121363. http://dx.doi.org/10.1016/j.lfs.2022.121363. 10.1016/j.lfs.2022.121363 André Furtado; André J. Esgalhado; Ana Catarina Duarte; Ana R. Costa; Ana R. Costa-Brito; Eva Carro; Hiroshi Ishikawa; et al. "Circadian rhythmicity of amyloid-beta-related molecules is disrupted in the choroid plexus of a female Alzheimer's disease mouse model". Journal of Neuroscience Research (2022): http://dx.doi.org/10.1002/jnr.25164. 10.1002/jnr.25164 Antonio Bovolini; Ana Raquel Costa-Brito; Faber Martins; Guilherme Eustáquio Furtado; Gonçalo V. Mendonça; Carolina Vila-Chã. "Impact of Exercise on Vascular Function in Middle-Aged and Older Adults: A Scoping Review". Sports (2022): https://doi.org/10.3390/sports10120208. 10.3390/sports10120208 Guilherme Eustáquio Furtado; Cláudia Vaz; Antonio Bovolini; Ermelinda Marques; Nuno Serra; Ana Raquel Costa-Brito; Carolina Vila-Chã. "The Impact of Physical Activity Levels and Functional Fitness Status on the Quality of Life Perceived by Older Adults Living in Rural and Urban Areas: The Portuguese Inland Case". Healthcare (2022): https://doi.org/10.3390/healthcare10071266. 10.3390/healthcare10071266 Costa-Brito, AnaR; Gonçalves, Isabel; Santos, CecíliaR. A.. Corresponding author: Santos, CecíliaR. A.. "The brain as a source and a target of prolactin in mammals". Neural Regeneration Research 17 8 (2022): 1695. http://dx.doi.org/10.4103/1673-5374.332124. Open access • 10.4103/1673-5374.332124 Costa-Brito, Ana R.; Quintela, Telma; Gonçalves, Isabel; Duarte, Ana C.; Costa, Ana R.; Arosa, Fernando A.; Cavaco, José E.; Lemos, Manuel C; SANTOS, Cecilia R A. "The Choroid Plexus Is an Alternative Source of Prolactin to the Rat Brain.". Molecular neurobiology 58 4 (2021): 1846-1858. https://doi.org/10.1007/s12035-020-02267-9. 10.1007/s12035-020-02267-9 Daniela Talhada; Ana Raquel Costa-Brito; Ana Catarina Duarte; Ana Raquel Costa; Telma Quintela; Joana Tomás; Isabel Gonçalves; Cecília Reis Alves Santos. "The choroid plexus: Simple structure, complex functions". Journal of Neuroscience Research 98 5 (2020): 751-753. https://doi.org/10.1002/jnr.24571. Published • 10.1002/jnr.24571 Costa-Brito, Ana R.; Cardoso, Elsa M.; Martinez, Jorge; Arosa, Fernando A.. "The JAK2V617F mutation is associated with anomalies in the frequency of monocytes, B cells, CD8+ T cells and NK cells". Blood Cells, Molecules, and Diseases 55 3 (2015): 208-210. http://dx.doi.org/10.1016/j.bcmd.2015.06.005. Published

Activities

Event organisation

	Event name Type of event (Role)	Institution / Organization
2017/11/14 - 2019/11/16	III International Congress in Health Sciences Research Trends in Aging and Cancer (2019/11/14 - 2019/11/16) Congress	Universidade da Beira Interior, Portugal
2019/07/04 - 2019/07/05	XIV CICS-UBI ANNUAL SYMPOSIUM (2019/07/04 - 2019/07/05) Symposium	Universidade da Beira Interior, Portugal
2018/07/05 - 2018/07/06	XIII CICS-UBI ANNUAL SYMPOSIUM (2018/07/05 - 2018/07/06) Symposium	Universidade da Beira Interior, Portugal

Distinctions

Award

2013	First place at the competition Start it up girl Empreendedorismo no feminino Parkurbis - Parque de Ciência e Tecnologia da Covilhã, S.A, Portugal

Other distinction

2020	FENS Grant and Voucher Programme grant for participating in the FENS 2020 Virtual Forum
2019	Bolsa Sociedade Portuguesa de Endocrinologia Diabetes e Metabolismo/Novartis Oncology em Patologia Hipofisária 2019