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talk on injury.". The American journal of pathology (2014): http://europepmc.org/abstract/med/25196308.
10.1016/j.ajpath.2014.07.022
- Satchi-Fainaro, Ronit. "Polymeric nanotheranostics for real-time non-invasive optical imaging of breast cancer progression
and drug release.". Cancer letters (2014): http://europepmc.org/abstract/med/24614283.
10.1016/j.canlet.2014.02.022
- Satchi-Fainaro, Ronit. "Anticancer polymeric nanomedicine bearing synergistic drug combination is superior to a mixture of
individually-conjugated drugs.". Journal of controlled release : official journal of the Controlled Release Society
(2014): http://europepmc.org/abstract/med/24862318.
10.1016/j.jconrel.2014.05.025
- Satchi-Fainaro, Ronit. "Synthesis and evaluation of new NIR-fluorescent probes for cathepsin B: ICT versus FRET as a turn-ON
mode-of-action.". Bioorganic & medicinal chemistry letters (2014): http://europepmc.org/abstract/med/24767838.
10.1016/j.bmcl.2014.04.022
- Satchi-Fainaro, Ronit. "Overcoming obstacles in microRNA delivery towards improved cancer therapy.". Drug delivery and
translational research (2014): http://europepmc.org/abstract/med/25786616.
10.1007/s13346-013-0160-0
- Satchi-Fainaro, Ronit. "Synthesis and use of QCy7-derived modular probes for the detection and imaging of biologically relevant
analytes.". Nature protocols (2014): http://europepmc.org/abstract/med/24309975.
10.1038/nprot.2013.166
- Satchi-Fainaro, Ronit. "Interfering cancer with polymeric siRNA nanomedicines.". Journal of biomedical nanotechnology
(2014): http://europepmc.org/abstract/med/24724498.
10.1166/jbn.2014.1715
- Satchi-Fainaro, Ronit. "Nano-sized polymers and liposomes designed to deliver combination therapy for cancer.". Current
opinion in biotechnology (2013): http://europepmc.org/abstract/med/23726153.
10.1016/j.copbio.2013.04.014
- Satchi-Fainaro, Ronit. "Poly(ethylene glycol)-paclitaxel-alendronate self-assembled micelles for the targeted treatment of
breast cancer bone metastases.". Biomaterials (2013): http://europepmc.org/abstract/med/23434349.
10.1016/j.biomaterials.2013.01.052
- Satchi-Fainaro, Ronit. "Hormonal regulation of pigment epithelium-derived factor (PEDF) in granulosa cells.". Molecular
human reproduction (2013): http://europepmc.org/abstract/med/23075882.
10.1093/molehr/gas046
- Satchi-Fainaro, Ronit. "Porfimer-sodium (Photofrin-II) in combination with ionizing radiation inhibits tumor-initiating cell
proliferation and improves glioblastoma treatment efficacy.". Cancer biology & therapy (2013): http://europepmc.org/abstract/med/23114641.
10.4161/cbt.22630
- Herzog, I.M.; Feldman, M.; Eldar-Boock, A.; Satchi-Fainaro, R.; Fridman, M.. "Design of membrane targeting tobramycin-based
cationic amphiphiles with reduced hemolytic activity". MedChemComm 4 1 (2013): 120-124. http://www.scopus.com/inward/record.url?eid=2-s2.0-84871781428&partnerID=MN8TOARS.
10.1039/c2md20162c
- Polyak, D.; Eldar-Boock, A.; Baabur-Cohen, H.; Satchi-Fainaro, R.. "Polymer conjugates for focal and targeted delivery of
drugs". Polymers for Advanced Technologies 24 9 (2013): 777-790. http://www.scopus.com/inward/record.url?eid=2-s2.0-84883051086&partnerID=MN8TOARS.
10.1002/pat.3158
- Satchi-Fainaro, Ronit. "Tumor-initiating cells of various tumor types exhibit differential angiogenic properties and react
differently to antiangiogenic drugs.". Stem cells (Dayton, Ohio) (2012): http://europepmc.org/abstract/med/22782858.
10.1002/stem.1170
- Satchi-Fainaro, Ronit. "Administration, distribution, metabolism and elimination of polymer therapeutics.". Journal of
controlled release : official journal of the Controlled Release Society (2012): http://europepmc.org/abstract/med/22286005.
10.1016/j.jconrel.2011.12.021
- Satchi-Fainaro, Ronit. "6''-Thioether tobramycin analogues: towards selective targeting of bacterial membranes.". Angewandte
Chemie (International ed. in English) (2012): http://europepmc.org/abstract/med/22499286.
10.1002/anie.201200761
- Satchi-Fainaro, Ronit. "Prospective identification of glioblastoma cells generating dormant tumors.". PloS one (2012):
http://europepmc.org/abstract/med/22970208.
10.1371/journal.pone.0044395
- Eldar-Boock, Anat; Miller, Keren; Sanchis, Joaquin; Lupu, Ruth; Vicent, Maria J.; Satchi-Fainaro, Ronit. "Integrin-assisted
drug delivery of nano-scaled polymer therapeutics bearing paclitaxel". Biomaterials 32 15 (2011): 3862-3874.
10.1016/j.biomaterials.2011.01.073
- Scomparin, Anna; Salmaso, Stefano; Bersani, Sara; Satchi-Fainaro, Ronit; Caliceti, Paolo. "Novel folated and non-folated pullulan
bioconjugates for anticancer drug delivery". European Journal of Pharmaceutical Sciences 42 5 (2011): 547-558.
10.1016/j.ejps.2011.02.012
- Polyak, Dina; Ryppa, Claudia; Eldar-Boock, Anat; Ofek, Paula; Many, Ariel; Licha, Kai; Kratz, Felix; Satchi-Fainaro, Ronit.
"Development of PEGylated doxorubicin-E-[c(RGDfK)(2)] conjugate for integrin-targeted cancer therapy". Polymers For Advanced
Technologies 22 1 (2011): 103-113.
10.1002/pat.1731
- Segal, Ehud; Pan, Huaizhong; Benayoun, Liat; Kopeckova, Pavla; Shaked, Yuval; Kopecek, Jindrich; Satchi-Fainaro, Ronit. "Enhanced
anti-tumor activity and safety profile of targeted nano-scaled HPMA copolymer-alendronate-TNP-470 conjugate in the treatment
of bone malignances". Biomaterials 32 19 (2011): 4450-4463.
10.1016/j.biomaterials.2011.02.059
- Miller, Keren; Eldar-Boock, Anat; Polyak, Dina; Segal, Ehud; Benayoun, Liat; Shaked, Yuval; Satchi-Fainaro, Ronit. "Antiangiogenic
Antitumor Activity of HPMA Copolymer-Paclitaxel-Alendronate Conjugate on Breast Cancer Bone Metastasis Mouse Model". Molecular
Pharmaceutics 8 4 (2011): 1052-1062.
10.1021/mp200083n
- Clementi, Chiara; Miller, Keren; Mero, Anna; Satchi-Fainaro, Ronit; Pasut, Gianfranco. "Dendritic Poly(ethylene glycol) Bearing
Paclitaxel and Alendronate for Targeting Bone Neoplasms". Molecular Pharmaceutics 8 4 (2011): 1063-1072.
10.1021/mp2001445
- Karton-Lifshin, Naama; Segal, Ehud; Omer, Liora; Portnoy, Moshe; Satchi-Fainaro, Ronit; Shabat, Doron. "A Unique Paradigm
for a Turn-ON Near-Infrared Cyanine-Based Probe: Noninvasive Intravital Optical Imaging of Hydrogen Peroxide". Journal
of the American Chemical Society 133 28 (2011): 10960-10965.
10.1021/ja203145v
- Fante, Cristina; Eldar-Boock, Anat; Satchi-Fainaro, Ronit; Osborn, Helen M. I.; Greco, Francesca. "Synthesis and Biological
Evaluation of a Polyglutamic Acid-Dopamine Conjugate: A New Antiangiogenic Agent". Journal of Medicinal Chemistry 54
14 (2011): 5255-5259.
10.1021/jm200382r
- Satchi-Fainaro, Ronit. "siRNA transfection by dendritic core-shell nanocarriers.". Journal of controlled release : official
journal of the Controlled Release Society (2010): http://europepmc.org/abstract/med/21529651.
10.1016/j.jconrel.2010.07.064
- Fischer, W.; Claderon, M.; Ofek, P.; Satchi-Fainaro, R.; Haag, R.. "siRNA transfection by dendritic core-shell nanocarriers.".
Journal of controlled release : official journal of the Controlled Release Society 148 1 (2010): http://www.scopus.com/inward/record.url?eid=2-s2.0-79960574183&partnerID=MN8TOARS.
- Weinstain, Roy; Segal, Ehud; Satchi-Fainaro, Ronit; Shabat, Doron. "Real-time monitoring of drug release". Chemical Communications
46 4 (2010): 553-555.
10.1039/b919329d
- Marom, Hanit; Miller, Keren; Bechor-Bar, Yossi; Tsarfaty, Galia; Satchi-Fainaro, Ronit; Gozin, Michael. "Toward Development
of Targeted Nonsteroidal Antiandrogen-1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic Acid-Gadolinium Complex for Prostate
Cancer Diagnostics". Journal of Medicinal Chemistry 53 17 (2010): 6316-6325.
10.1021/jm100289b
- David, Ayelet; Satchi-Fainaro, Ronit. "Polymer Therapeutics-From Bench to Bedside". Israel Journal of Chemistry 50
2 (2010): 145-146.
10.1002/ijch.201000030
- Ofek, Paula; Miller, Keren; Eldar-Boock, Anat; Polyak, Dina; Segal, Ehud; Satchi-Fainaro, Ronit. "Rational Design of Multifunctional
Polymer Therapeutics for Cancer Theranostics". Israel Journal of Chemistry 50 2 (2010): 185-203.
10.1002/ijch.201000020
- Ofek, Paula; Fischer, Wiebke; Calderon, Marcelo; Haag, Rainer; Satchi-Fainaro, Ronit. "In vivo delivery of small interfering
RNA to tumors and their vasculature by novel dendritic nanocarriers". Faseb Journal 24 9 (2010): 3122-3134.
10.1096/fj.09-149641
- Segal, Ehud; Pan, Huaizhong; Ofek, Paula; Udagawa, Taturo; Kopeckova, Pavla; Kopecek, Jindrich; Satchi-Fainaro, Ronit. "Targeting
Angiogenesis-Dependent Calcified Neoplasms Using Combined Polymer Therapeutics". Plos One 4 4 (2009):
10.1371/journal.pone.0005233
- Miller, Keren; Erez, Rotem; Segal, Ehud; Shabat, Doron; Satchi-Fainaro, Ronit. "Targeting Bone Metastases with a Bispecific
Anticancer and Antiangiogenic Polymer-Alendronate-Taxane Conjugate". Angewandte Chemie-International Edition 48 16
(2009): 2949-2954.
10.1002/anie.200805133
- Erez, Rotem; Segal, Ehud; Miller, Keren; Satchi-Fainaro, Ronit; Shabat, Doron. "Enhanced cytotoxicity of a polymer-drug conjugate
with triple payload of paclitaxel". Bioorganic & Medicinal Chemistry 17 13 (2009): 4327-4335.
10.1016/j.bmc.2009.05.028
- Ryppa, Claudia; Mann-Steinberg, Hagit; Biniossek, Martin L.; Satchi-Fainaro, Ronit; Kratz, Felix. "In vitro and in vivo evaluation
of a paclitaxel conjugate with the divalent peptide E-[c(RGDfK)(2)] that targets integrin alpha(v)beta(3)". International
Journal of Pharmaceutics 368 1-2 (2009): 89-97.
10.1016/j.ijpharm.2008.09.055
- Stern, Liron; Perry, Rotem; Ofek, Paula; Many, Ariel; Shabat, Doron; Satchi-Fainaro, Ronit. "A Novel Antitumor Prodrug Platform
Designed to Be Cleaved by the Endoprotease Legumain". Bioconjugate Chemistry 20 3 (2009): 500-510.
10.1021/bc800448u
- Segal, Ehud; Satchi-Fainaro, Ronit. "Design and development of polymer conjugates as anti-angiogenic agents". Advanced
Drug Delivery Reviews 61 13 (2009): 1159-1176.
10.1016/j.addr.2009.06.005
- Ryppa, Claudia; Mann-Steinberg, Hagit; Fichtner, Iduna; Weber, Holger; Satchi-Fainaro, Ronit; Biniossek, Martin L.; Kratz,
Felix. "In vitro and in vivo evaluation of doxorubicin conjugates with the divalent peptide E-[c(RGDfK)(2)] that targets integrin
alpha(v)beta(3)". Bioconjugate Chemistry 19 7 (2008): 1414-1422.
10.1021/bc800117r
- Sagi, Amit; Segal, Ehud; Satchi-Fainaro, Ronit; Shabat, Doron. "Remarkable drug-release enhancement with an elimination-based
AB(3) self-immolative dendritic amplifier". Bioorganic & Medicinal Chemistry 15 11 (2007): 3720-3727.
10.1016/j.bmc.2007.03.054
- Nahari, Dorit; Satchi-Fainaro, Ronit; Chen, Ming; Mitchell, Ian; Task, Laurie B.; Liu, Zijuan; Kihneman, Jason; et al. "Tumor
cytotoxicity and endothelial Rac inhibition induced by TNP-470 in anaplastic thyroid cancer". Molecular Cancer Therapeutics
6 4 (2007): 1329-1337.
10.1158/1535-7163.MCT-06-0554
- Chesler, Louis; Goldenberg, David D.; Seales, Isha T.; Satchi-Fainaro, Ronit; Grimmer, Matt; Collins, Rodney; Struett, Chris;
et al. "Malignant progression and blockade of angiogenesis in a murine transgenic model of neuroblastoma". Cancer Research
67 19 (2007): 9435-9442.
10.1158/0008-5472.CAN-07-1316
- Satchi-Fainaro, R; Duncan, R; Barnes, CM; SatchiFainaro, R. "Polymer therapeutics for cancer: Current status and future challenges".
Polymer Therapeutics Ii: Polymers As Drugs, Conjugates and Gene Delivery Systems 193 (2006): 1-65.
10.1007/12_024
- Duncan, R; Ringsdorf, H; Satchi-Fainaro, R; SatchiFainaro, R. "Polymer therapeutics: Polymers as drugs, drug and protein conjugates
and gene delivery systems: Past, present and future opportunities". Polymer Therapeutics I: Polymers As Drugs, Conjugates
and Gene Delivery Systems 192 (2006): 1-8.
10.1007/12_037
- Duncan, Ruth; Ringsdorf, Helmut; Satchi-Fainaro, Ronit. "Polymer therapeutics - polymers as drugs, drug and protein conjugates
and gene delivery systems: Past, present and future opportunities (Reprinted from Advances in Polymer Science, vol 192, pg
1-8, 2005)". Journal of Drug Targeting 14 6 (2006): 337-341.
10.1080/10611860600833856
- Becker, CM; Wright, RD; Satchi-Fainaro, R; Funakoshi, T; Folkman, J; Kung, AL; D'Amato, RJ. "A novel noninvasive model of
endometriosis for monitoring the efficacy of antiangiogenic therapy". American Journal of Pathology 168 6 (2006): 2074-2084.
10.2353/ajpath.2006.051133
- Satchi-Fainaro, R; Mamluk, R; Wang, L; Short, SM; Nagy, JA; Feng, D; Dvorak, AM; et al. "Inhibition of vessel permeability
by TNP-470 and its polymer conjugate, caplostatin". Cancer Cell 7 3 (2005): 251-261.
10.1016/j.ccr.2005.02.007
- Javid, PJ; Greene, AK; Garza, J; Gura, K; Alwayn, IPJ; Voss, S; Nose, V; et al. "The route of lipid administration affects
parenteral nutrition-induced hepatic steatosis in a mouse model". Journal of Pediatric Surgery 40 9 (2005): 1446-1453.
10.1016/j.jpedsurg.2005.05.045
- Tjin, RM; Sjin, T; Satchi-Fainaro, R; Birsner, AE; Ramanujam, VMS; Folkman, J; Javaherian, K. "A 27-amino-acid synthetic peptide
corresponding to the NH2-terminal zinc-binding domain of endostatin is responsible for its antitumor activity". Cancer
Research 65 9 (2005): 3656-3663.
10.1158/0008-5472.CAN-04-1833
- Perino, S; Contino-Pepin, C; Satchi-Fainaro, R; Butterfield, C; Pucci, B. "Inhibition of angiogenesis by THAM-derived cotelomers
endowed with thalidomide moieties". Bioorganic & Medicinal Chemistry Letters 14 2 (2004): 421-425.
10.1016/j.bmcl.2003.10.045
- Satchi-Fainaro, R; Puder, M; Davies, JW; Tran, HT; Sampson, DA; Greene, AK; Corfas, G; Folkman, J. "Targeting angiogenesis
with a conjugate of HPMA copolymer and TNP-470". Nature Medicine 10 3 (2004): 255-261.
10.1038/nm1002
- Satchi-Fainaro, R; Hailu, H; Davies, JW; Summerford, C; Duncan, R. "PDEPT: Polymer-directed enzyme prodrug therapy. 2. HPMA
copolymer-beta-lactamase and HPMA copolymer-C-Dox as a model combination". Bioconjugate Chemistry 14 4 (2003): 797-804.
10.1021/bc020091k
- Satchi-Fainaro, R. "Targeting tumor vasculature: Reality or a dream?". Journal of Drug Targeting 10 7 (2002): 529-533.
10.1080/1061186021000051062
- Satchi-Fainaro, R; Wrasidlo, W; Lode, HN; Shabat, D. "Synthesis and characterization of a catalytic antibody-HPMA copolymer-conjugate
as a tool for tumor selective prodrug activation". Bioorganic & Medicinal Chemistry 10 9 (2002): 3023-3029.
10.1016/S0968-0896(02)00156-6
- Duncan, R; Gac-Breton, S; Keane, R; Musila, R; Sat, YN; Satchi, R; Searle, F. "Polymer-drug conjugates, PDEPT and PELT: basic
principles for design and transfer from the laboratory to clinic". Journal of Controlled Release 74 1-3 (2001): 135-146.
10.1016/S0168-3659(01)00328-5
- Satchi, R; Connors, TA; Duncan, R. "PDEPT: polymer-directed enzyme prodrug therapy I. HPMA copolymer-cathepsin B and PK1 as
a model combination". British Journal of Cancer 85 7 (2001): 1070-1076.
10.1038/sj.bjc.6692026
- Satchi, R.; Connors, T.A.; Duncan, R.. "PDEPT: In vivo pharmacokinetics and pharmacology". Proceedings of the Controlled
Release Society 26 (1999): 126-127. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032710587&partnerID=MN8TOARS.
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