Tiago Oliveira (A815-C812-406D)

Curriculum Vitae

Tiago Oliveira

Tiago Franco de Oliveira currently works at Universidade Federal de Ciências da Saúde de Porto Alegre as Head of Pharmacosciences Department. He has a PhD in Toxicology with extensive training in Mass Spectrometry and published 31 articles in journals. Dr. Oliveira serves as President of Brazilian Society of Toxicology - SBTOX (2020-2021). Additionally, he is member of Brazilian Society of Mass Spectrometry (BrMass), Hispanic Organization of Toxicology (HOT), Society of Toxicology (SOT-USA), and of The International Association of Forensic Toxicologists (TIAFT). His research is focused on development of Mass Spectrometry methods and its application in Toxicology and Metabolomics.

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Identification

Personal identification

Full name: Tiago Oliveira

Citation names

Oliveira, Tiago
Oliveira, T.F.
de Oliveira, TF
Oliveira, T

Author identifiers

Ciência ID: A815-C812-406D
ORCID iD: 0000-0003-2594-8415
Researcher Id: A-8826-2012

Telephones

Telephone

(+55) 5133038883 (Professional)

Addresses

Sarmento Leite Street, 245, 001B, 90050-170, Rio Grande do Sul, Porto Alegre, Brazil (Professional)

Websites

https://www.ufcspa.edu.br/ (Professional)
https://www.analiticaufcspa.org/ (Personal)

Knowledge fields

Medical and Health Sciences - Basic Medicine - Toxicology
Medical and Health Sciences - Basic Medicine - Toxicology

Languages

Language	Speaking	Reading	Writing	Listening	Peer-review
Portuguese (Mother tongue)
English	Proficiency (C2)	Proficiency (C2)	Proficiency (C2)	Proficiency (C2)	Proficiency (C2)

Education

	Degree	Classification
2013 - 2017 Concluded	Transformation of human bronchial epithelial cells by benzo[a]pyrene: redox metabolic processes and DNA methylation / demethylation (Pós-doutoramento) Universidade de São Paulo, Brazil
2008 - 2012 Concluded	Toxicology and Toxicological Analyses (Doutoramento) Universidade de São Paulo, Brazil "Cytotoxicity of the CI DB291 dinitrofenilazo dye: biotransformation, oxidative stress and epigenetic change in HepG2 cells" (THESIS/DISSERTATION)
2003 - 2007 Concluded	Biomedical Sciences (Bacharelato) Faculdades Integradas Einstein de Limeira, Brazil

Affiliation

Teaching in Higher Education

	Category Host institution	Employer
2017 - Current	Associate Professor (University Teacher)	Universidade Federal de Ciências da Saúde de Porto Alegre, Brazil
	Universidade Federal de Ciências da Saúde de Porto Alegre, Brazil

Projects

Other

	Designation	Funders
2019 - Current	Analytical methods for identification of new psychoactive substances (NPS) of clinical and forensic interest by high resolution mass spectrometry 423504/2018-5 Principal investigator Universidade Federal de Ciências da Saúde de Porto Alegre, Brazil	Conselho Nacional de Desenvolvimento Científico e Tecnológico Ongoing
2014 - 2017	Transformation of human bronchial epithelial cells by benzo [a] pyrene: redox metabolic processes and DNA methylation / demethylation 454214/2014-6 Post-doc Universidade de São Paulo, Brazil	Conselho Nacional de Desenvolvimento Científico e Tecnológico Concluded

Outputs

Publications

Journal article

Bruno Pereira dos Santos; Giovanna Cristiano de Gouveia; Sarah Eller; Ana Miguel Fonseca Pego; Viviane Cristina Sebben; Tiago Franco de Oliveira. "Is COVID-19 the current world-wide pandemic having effects on the profile of psychoactive substance poisonings?". Forensic Toxicology 39 1 (2021): 282-285. https://doi.org/10.1007/s11419-020-00558-3.
10.1007/s11419-020-00558-3
Everton Rafael Campos; Sarah Eller; Leticia Birk; Masurquede Azevedo Coimbra; Sandra Manoela Dias Macedo; Mauricio Yonamine; Josias Oliveira Merib; Tiago Franco de Oliveira. "Analysis of seized stanozolol formulations in South Brazil by liquid chromatography coupled to quadrupole time-of-flight-mass spectrometry". Drug Analytical Research (2020): https://doi.org/10.22456/2527-2616.108853.
10.22456/2527-2616.108853
Sarah Eller; Alexandre Dias Zucoloto; Carolina Dizioli Rodrigues de Oliveira; Edna Maria Miello Hernandez; Ligia Veras Gimenez Fruchtengarten; Flávia Neri Meira de Oliveira; Tiago Franco de Oliveira; Mauricio Yonamine. "Multivariate analysis applied in dataset of Poison Control Center of São Paulo, Brazil". Scientific Reports (2020): https://doi.org/10.1038/s41598-020-66485-w.
10.1038/s41598-020-66485-w
Oliveira, T.F.. "Accidental ingestion of methyl ethyl ketone peroxide: N-acetylcysteine treatment and toxicological analysis". Clinica Chimica Acta (2020): http://dx.doi.org/10.1016/j.cca.2020.09.034.
10.1016/j.cca.2020.09.034
Oliveira, T.F.. "A rapid analytical strategy for the determination of ayahuasca alkaloids in non-ritualistic approaches by UHPLC-MS/MS". Forensic Science International (2020): http://dx.doi.org/10.1016/j.forsciint.2020.110298.
10.1016/j.forsciint.2020.110298
Oliveira, T.F.. "A straightforward and semiautomated membrane-based method as efficient tool for the determination of cocaine and its metabolites in urine samples using liquid chromatography coupled to quadrupole time-of-flight-mass spectrometry". Journal of Chromatography A (2020): http://dx.doi.org/10.1016/j.chroma.2020.461088.
10.1016/j.chroma.2020.461088
Oliveira, T.F.. "A green and low-cost method employing switchable hydrophilicity solvent for the simultaneous determination of antidepressants in human urine by gas chromatography - mass spectrometry detection". Journal of Chromatography B (2020): http://dx.doi.org/10.1016/j.jchromb.2020.122069.
10.1016/j.jchromb.2020.122069
Oliveira, Tiago. "Stability in clinical use and stress testing of meropenem antibiotic by direct infusion ESI-Q-TOF: Quantitative method and identification of degradation products". Journal of Pharmaceutical and Biomedical Analysis (2020): http://dx.doi.org/10.1016/j.jpba.2019.112973.
10.1016/j.jpba.2019.112973
Oliveira, Tiago. "Simple and straightforward analysis of cannabinoids in medicinal products by fast-GC–FID". Forensic Toxicology (2020): http://dx.doi.org/10.1007/s11419-020-00522-1.
10.1007/s11419-020-00522-1
Oliveira, Tiago. "A low-voltage paper spray ionization QTOF-MS method for the qualitative analysis of NPS in street drug blotter samples". Forensic Toxicology (2020): http://dx.doi.org/10.1007/s11419-019-00496-9.
10.1007/s11419-019-00496-9
Oliveira, Tiago. "Microwave-synthesized KNbO3 perovskites: photocatalytic pathway on the degradation of rhodamine B". Ceramics International (2019): http://dx.doi.org/10.1016/j.ceramint.2019.08.122.
10.1016/j.ceramint.2019.08.122
Oliveira, Tiago. "Distinct inflammatory profiles in HIV-infected individuals under antiretroviral therapy using cannabis, cocaine or cannabis plus cocaine". AIDS (2019): http://dx.doi.org/10.1097/qad.0000000000002296.
10.1097/qad.0000000000002296
Oliveira, Tiago. "A fast and simple approach for the quantification of 40 illicit drugs, medicines, and pesticides in blood and urine samples by UHPLC-MS/MS". Journal of Mass Spectrometry (2019): http://dx.doi.org/10.1002/jms.4369.
10.1002/jms.4369
Oliveira, Tiago. "Quantification of three DNA Lesions by Mass Spectrometry and Assessment of Their Levels in Tissues of Mice Exposed to Ambient Fine Particulate Matter". Journal of Visualized Experiments (2019): http://dx.doi.org/10.3791/59734.
10.3791/59734
Francis Ribeiro de Souza; Marcelo Rodrigues Dos Santos; Rafael Armani Porello; Guilherme Wesley Peixoto da Fonseca; Ana Luiza Carrari Sayegh; Thaís Pinheiro Lima; Fabiana Dias Ferreira; et al. "Diminished cholesterol efflux mediated by HDL and coronary artery disease in young male anabolic androgenic steroid users". Atherosclerosis 283 (2019): 100-105. https://doi.org/10.1016/j.atherosclerosis.2019.02.006.
10.1016/j.atherosclerosis.2019.02.006
Oliveira, Tiago. "Global DNA methylation of peripheral blood leukocytes from dogs bearing multicentric non-Hodgkin lymphomas and healthy dogs: A comparative study". PLOS ONE (2019): http://dx.doi.org/10.1371/journal.pone.0211898.
10.1371/journal.pone.0211898
Oliveira, Tiago. "Retrograde and oscillatory shear rate in young anabolic androgenic steroid users". Scandinavian Journal of Medicine & Science in Sports (2019): http://dx.doi.org/10.1111/sms.13332.
10.1111/sms.13332
de Souza Barbosa, F.; Capra Pezzi, L.; Tsao, M.; Franco de Oliveira, T.; Manoela Dias Macedo, S.; E.S. Schapoval, E.; S.L. Mendez, A.. "Stability and degradation products of imipenem applying high-resolution mass spectrometry: An analytical study focused on solutions for infusion". Biomedical Chromatography (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85059617884&partnerID=MN8TOARS.
10.1002/bmc.4471
Oliveira, Tiago. "Blue-green discoloration of urine and false nephrotic range proteinuria at dipstick urinalysis". Clinica Chimica Acta (2018): http://dx.doi.org/10.1016/j.cca.2018.03.036.
10.1016/j.cca.2018.03.036
Bassani, D.; Da Silva, L.R.; Birk, L.; Franco De Oliveira, S.C.W.D.S.E.; Dallegrave, E.; De Oliveira, T.F.. "Pesticides in Brazil: A Viewpoint about the Poison Law". Journal of Agricultural and Food Chemistry 66 46 (2018): 12153-12154. http://www.scopus.com/inward/record.url?eid=2-s2.0-85056573273&partnerID=MN8TOARS.
10.1021/acs.jafc.8b05669
Franco de Oliveira, S.C.W.S.E.; Zucoloto, A.D.; de Oliveira, C.D.R.; Hernandez, E.M.M.; Fruchtengarten, L.V.G.; de Oliveira, T.F.; Yonamine, M.. "Development of a simple HPLC-DAD multi-analyte procedure and its application in cases evaluated by the Poison Control Center of São Paulo, Brazil". Biomedical Chromatography 32 12 (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85053454801&partnerID=MN8TOARS.
10.1002/bmc.4360
Porello, R.A.; Dos Santos, M.R.; De Souza, F.R.; Da Fonseca, G.W.P.; Sayegh, A.L.C.; De Oliveira, T.F.; Akiho, C.A.; et al. "Neurovascular Response during Exercise and Mental Stress in Anabolic Steroid Users". Medicine and Science in Sports and Exercise 50 3 (2018): 596-602. http://www.scopus.com/inward/record.url?eid=2-s2.0-85042390535&partnerID=MN8TOARS.
10.1249/MSS.0000000000001456
Fonseca Pego, A.M.; Franco de Oliveira, S.C.W.D.S.E.; Franco de Oliveira, T.; Leyton, V.; Miziara, I.; Yonamine, M.. "Cocaine toxicological findings in cases of violent death in Sao Paulo city - Brazil". Journal of Forensic and Legal Medicine 60 (2018): 3-8. http://www.scopus.com/inward/record.url?eid=2-s2.0-85052880373&partnerID=MN8TOARS.
10.1016/j.jflm.2018.08.005
De Oliveira, A.A.F.; De Oliveira, T.F.; Dias, M.F.; Medeiros, M.H.G.; Di Mascio, P.; Veras, M.; Lemos, M.; et al. "Genotoxic and epigenotoxic effects in mice exposed to concentrated ambient fine particulate matter (PM2.5) from São Paulo city, Brazil". Particle and Fibre Toxicology 15 1 (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85055078429&partnerID=MN8TOARS.
10.1186/s12989-018-0276-y
Almondes, K.G.S.; Cardoso, B.R.; Cominetti, C.; Nogueira, N.N.; Marreiro, D.N.; Oliveira, T.F.; Loureiro, A.P.M.; Cozzolino, S.M.F.. "The redox balance of healthy Brazilian adults is associated with GPX1 Pro198Leu and -602A/G polymorphisms, selenium status, and anthropometric and lifestyle parameters". Food and Function 9 10 (2018): 5313-5322. http://www.scopus.com/inward/record.url?eid=2-s2.0-85055077349&partnerID=MN8TOARS.
10.1039/c8fo01621f
Serafim, R.A.M.; de Oliveira, T.F.; Loureiro, A.P.M.; Krogh, R.; Andricopulo, A.D.; Dias, L.C.; Ferreira, E.I.. "Molecular modeling and structure–activity relationships studies of bioisoster hybrids of N-acylhydrazone and furoxan groups on cruzain". Medicinal Chemistry Research 26 4 (2017): 760-769. http://www.scopus.com/inward/record.url?eid=2-s2.0-85010773987&partnerID=MN8TOARS.
10.1007/s00044-016-1776-7
De Oliveira, A.A.F.; De Oliveira, T.F.; Bobadilla, L.L.; Garcia, C.C.M.; Berra, C.M.; De Souza-Pinto, N.C.; Medeiros, M.H.G.; et al. "Sustained kidney biochemical derangement in treated experimental diabetes: A clue to metabolic memory". Scientific Reports 7 (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85009433465&partnerID=MN8TOARS.
10.1038/srep40544
Takitane, J.; Almeida, R.M.; Oliveira, T.F.; Prado, N.V.; Muñoz, D.R.; Leyton, V.; Yonamine, M.. "Determination of amphetamine, amfepramone and fenproporex in urine samples by HPLC-DAD: Application to a population of Brazilian truck drivers". Journal of the Brazilian Chemical Society 27 3 (2016): 624-630. http://www.scopus.com/inward/record.url?eid=2-s2.0-84960384263&partnerID=MN8TOARS.
10.5935/0103-5053.20150305
Oliveira, T.F.. "Estimativa da Incerteza de Medição em Análises de Benzoilecgonina em Urina por GC-MS". Brazilian Journal of Forensic Sciences, Medical Law and Bioethics (2016): http://dx.doi.org/10.17063/bjfs5(2)y2016215.
10.17063/bjfs5(2)y2016215
de Oliveira Andrade, F.; Fontelles, C.C.; Rosim, M.P.; de Oliveira, T.F.; de Melo Loureiro, A.P.; Mancini-Filho, J.; Rogero, M.M.; et al. "Exposure to lard-based high-fat diet during fetal and lactation periods modifies breast cancer susceptibility in adulthood in rats". Journal of Nutritional Biochemistry 25 6 (2014): 613-622. http://www.scopus.com/inward/record.url?eid=2-s2.0-84899914468&partnerID=MN8TOARS.
10.1016/j.jnutbio.2014.02.002
Heidor, R.; Furtado, K.S.; Ortega, J.F.; de Oliveira, T.F.; Tavares, P.E.L.M.; Vieira, A.; Miranda, M.L.P.; Purgatto, E.; Moreno, F.S.. "The chemopreventive activity of the histone deacetylase inhibitor tributyrin in colon carcinogenesis involves the induction of apoptosis and reduction of DNA damage". Toxicology and Applied Pharmacology 276 2 (2014): 129-135. http://www.scopus.com/inward/record.url?eid=2-s2.0-84897954301&partnerID=MN8TOARS.
10.1016/j.taap.2014.02.004
Almondes, K.G.D.S.; Oliveira, T.F.D.; Siviero-Miachon, A.A.; Lee, M.L.D.M.; Rondó, P.H.D.C.; Loureiro, A.P.D.M.; Spinola-Castro, T.M.; Cozzolino, S.M.F.. "Selenium inadequacy is not associated with oxidative stress in child and adolescent acute lymphocytic leukemia survivors". Nutrition 30 5 (2014): 563-568. http://www.scopus.com/inward/record.url?eid=2-s2.0-84897067176&partnerID=MN8TOARS.
10.1016/j.nut.2013.10.012
De Oliveira, T.F.; Da Silva, A.L.M.; De Moura, R.A.; Bagattini, R.; De Oliveira, A.A.F.; De Medeiros, M.H.G.; Di Mascio, P.; et al. "Luminescent threat: Toxicity of light stick attractors used in pelagic fishery". Scientific Reports 4 (2014): http://www.scopus.com/inward/record.url?eid=2-s2.0-84902840496&partnerID=MN8TOARS.
10.1038/srep05359
Bastos, A.S.; Loureiro, A.P.D.M.; Oliveira, T.F.D.; Corbi, S.C.T.; Caminaga, R.M.S.; Rossa Jr., C.; Orrico, S.R.P.. "Quantitation of malondialdehyde in gingival crevicular fluid by a high-performance liquid chromatography-based method". Analytical Biochemistry 423 1 (2012): 141-146. http://www.scopus.com/inward/record.url?eid=2-s2.0-84857408101&partnerID=MN8TOARS.
10.1016/j.ab.2012.01.016
Brohem, C.A.; Massaro, R.R.; Tiago, M.; Marinho, C.E.; Jasiulionis, M.G.; de Almeida, R.L.; Rivelli, D.P.; et al. "Proteasome inhibition and ROS generation by 4-nerolidylcatechol induces melanoma cell death". Pigment Cell and Melanoma Research 25 3 (2012): 354-369. http://www.scopus.com/inward/record.url?eid=2-s2.0-84865310953&partnerID=MN8TOARS.
10.1111/j.1755-148X.2012.00992.x
Garcia, C.C.M.; Angeli, J.P.F.; Freitas, F.P.; Gomes, O.F.; De Oliveira, T.F.; Loureiro, A.P.M.; Di Mascio, P.; Medeiros, M.H.G.. "[¹³C2]-acetaldehyde promotes unequivocal formation of 1, N ²-propano-2'-deoxyguanosine in human cells". Journal of the American Chemical Society 133 24 (2011): 9140-9143. http://www.scopus.com/inward/record.url?eid=2-s2.0-79959203849&partnerID=MN8TOARS.
10.1021/ja2004686
Ribeiro, A.L.T.; Shimada, A.L.B.; Hebeda, C.B.; de Oliveira, T.F.; de Melo Loureiro, A.P.; Filho, W.D.R.P.; Santos, A.M.D.A.; de Lima, W.T.; Farsky, S.H.P.. "In vivo hydroquinone exposure alters circulating neutrophil activities and impairs LPS-induced lung inflammation in mice". Toxicology 288 1-3 (2011): 1-7. http://www.scopus.com/inward/record.url?eid=2-s2.0-79961032694&partnerID=MN8TOARS.
10.1016/j.tox.2011.05.009
Bianchi, F.J.; De Oliveira, T.F.; Saito, C.B.P.; Peres, R.C.R.; Line, S.R.P.. "Association between polymorphism in the promoter region (G/C-915) of PAX9 gene and third molar agenesis". Journal of Applied Oral Science 15 5 (2007): 382-386. http://www.scopus.com/inward/record.url?eid=2-s2.0-36448940137&partnerID=MN8TOARS.
10.1590/S1678-77572007000500002

Activities

Supervision

	Thesis Title Role	Degree Subject (Type) Institution / Organization
2020 - Current	Characterization of in vitro biotransformation products of synthetic 4'-fluoro-a-pyrrolidinohexanophenone, eutilone and diethyl pentylone cathinones Supervisor of Gabriela Ramos Borges	Health Sciences (Master) Universidade Federal de Ciências da Saúde de Porto Alegre, Brazil
2020 - Current	Evaluation and quantification of psychoactive substances in cases of violent death Supervisor of Amanda Silva	Health Sciences (Master) Universidade Federal de Ciências da Saúde de Porto Alegre, Brazil
2020 - Current	Determination of medicines and drugs of abuse in emergency toxicological samples by paper spray ionization and high resolution mass spectrometry Supervisor of Bruno Pereira Santos	Health Sciences (Master) Universidade Federal de Ciências da Saúde de Porto Alegre, Brazil
2019 - Current	Identification of synthetic cathinones by liquid chromatography coupled with high resolution mass spectrometry Supervisor of Letícia Birk	Health Sciences (Master) Universidade Federal de Ciências da Saúde de Porto Alegre, Brazil
2019 - Current	Determination of NBOMes in blood samples using ionic liquid microextraction techniques Supervisor of Camila Scheid	Health Sciences (Master) Universidade Federal de Ciências da Saúde de Porto Alegre, Brazil
2019 - Current	Chemical and microbiological analysis of anabolic androgenic steroids seized by the Federal Revenue Service in correspondence in Rio Grande do Sul Supervisor of Masurquede de Azevedo Coimbra	Health Sciences (Master) Universidade Federal de Ciências da Saúde de Porto Alegre, Brazil
2019 - Current	DILUTE-and-SHOOT-HRMS for quantification of vancomycin in plasma samples Supervisor of Fernanda Ribeiro Vidal	Health Sciences (Master) Universidade Federal de Ciências da Saúde de Porto Alegre, Brazil
2019 - Current	Role of caffeine and adenosine receptors in alcohol abstinence Supervisor of Paulo Ricardo Fernandes	Health Sciences (PhD) Universidade Federal de Ciências da Saúde de Porto Alegre, Brazil
2018 - Current	Development and validation of an analytical method for the evaluation of exposure to pyrethroid and neonicotinoid pesticides Co-supervisor of Thaís Spohr Christ	Pharmacy (PhD) Universidade Federal do Rio Grande do Sul, Brazil
2018/03 - 2020/02	Development and validation of multiresidue method DBS-LC-MS / MS for analysis of pesticides as biomarkers Supervisor of Lauren Ramos da Silva	Health Sciences (Master) Universidade Federal de Ciências da Saúde de Porto Alegre, Brazil
2019 - 2020	Therapeutic monitoring of vancomycin in DBS by UHPLC-MS / MS Supervisor of Daniela Souza Ossanes	Biomedical science (Scientific initiation) Universidade Federal de Ciências da Saúde de Porto Alegre, Brazil
2019 - 2020	Determination of antidepressants in human milk bank samples by HRMS Supervisor of Everton Madeira Vivian	Biomedical Science (Scientific initiation) Universidade Federal de Ciências da Saúde de Porto Alegre, Brazil
2019 - 2020	Determination of NBOH in blood samples using microextraction techniques Supervisor of Sofia Aquino Monteiro	Biomedical Science (Scientific initiation) Universidade Federal de Ciências da Saúde de Porto Alegre, Brazil
2019 - 2020	HRMS identification of synthetic cathinones Supervisor of Sara Oberlaender Santos	Medicinal Chemistry (Scientific initiation) Universidade Federal de Ciências da Saúde de Porto Alegre, Brazil
2018 - 2019	Development and validation of the multi-residue mini QuEChERS method for pesticide analysis Supervisor of Luiz Carlos Ferreira Neto	Biomedical Science (Scientific initiation) Universidade Federal de Ciências da Saúde de Porto Alegre, Brazil
2013 - 2014	Exposure of human bronchial epithelial cells to low concentrations of benzo[a]pyrene: genotoxicity, epigenetic alteration and malignant transformation Supervisor	Biomedical science (Scientific initiation) Universidade de São Paulo, Brazil