Inês Pereira Dias Marques (A816-8461-F97D)

Curriculum Vitae

Inês Pereira Dias Marques

Inês Pereira Dias Marques. Concluiu a Licenciatura em Medicina em 2005 pela Faculdade de Medicina da Universidade de Coimbra. Concluiu o Doutoramento em Ciências da Saúde pela Faculdade de Medicina da Universidade de Coimbra a 17 de Setembro de 2021, com o título "PROGRESS- Progression of Diabetic Retinopathy. Identification of signs and Surrogate outcomes". É Directora do Centro de Ensaios Clínicos na Associação para a Investigação Biomédica e Inovação em Luz e Imagem (AIBILI), Investigadora na AIBILI e Coordenadora de projetos e grader médico no Coimbra ophthalmology reading center (CORC), AIBILI. Publicou 18 artigos em revistas especializadas. Possui 3 capítulos de livros. Coorientou 1 dissertação de mestrado. Recebeu 4 prémios. Participa e/ou participou como Investigadora em 35 projetos e é Investigador principal em 1 projeto. Exerce actividade clínica como oftalmologista na AIBILI e outras clínicas.

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Identification

Personal identification

Full name: Inês Pereira Dias Marques

Citation names

Marques, Inês P
Marques, I
Marque, IP

Author identifiers

Ciência ID: A816-8461-F97D
ORCID iD: 0000-0001-9170-6997
Scopus Author Id: 54789056900

Email addresses

ipmarques@aibili.pt (Professional)
inespdmarques@gmail.com (Personal)

Addresses

AIBILI, Azinhaga de Santa Comba, Celas, 3000-548, Coimbra, Coimbra, Portugal (Professional)

Websites

https://www.aibili.pt/units-centres/cec/ (Professional)
https://www.aibili.pt/units-centres/corc/ (Professional)

Knowledge fields

Medical and Health Sciences - Clinical Medicine - Ophthalmology

Languages

Language	Speaking	Reading	Writing	Listening	Peer-review
Portuguese (Mother tongue)
English	Proficiency (C2)	Advanced (C1)	Advanced (C1)	Advanced (C1)	Advanced (C1)
French	Advanced (C1)	Advanced (C1)	Advanced (C1)	Advanced (C1)	Advanced (C1)
Spanish; Castilian	Intermediate (B1)	Upper intermediate (B2)	Elementary (A2)	Intermediate (B1)	Intermediate (B1)

Education

	Degree	Classification
2022/03/10 - 2022/03/10 Concluded	Grau de consultor da carreira médica (Outros) Centro Hospitalar Tondela Viseu EPE, Portugal	Aprovado
2014 - 2020/09/17 Concluded	Doutoramento em Ciências da Saúde (Doutoramento) Universidade de Coimbra Faculdade de Medicina, Portugal "PROGRESS – Progression of Diabetic Retinopathy. Identification of Signs and Surrogate outcomes." (THESIS/DISSERTATION)
2020/02/19 - 2020/02/19 Concluded	ICH-GCP in English (R2 version) Exam (Outros) Major in Clinical Research Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal
2013 - 2015 Concluded	European Retina Panel (ERP) II Program (Outros) Major in Retina Allergan AG, Switzerland
2013/04/26 - 2013/04/27 Concluded	European Board of Ophthalmology Diploma (EBOD) (Postgraduate Certificate) Major in Ophthalmology European Board of Ophthalmology, Ireland	178,5 valores (0- 200)
2012/01/31 - 2012/11/08 Concluded	Principles and Practice of Clinical Research (Outros) Harvard Medical School, United States
2012/10/20 - 2012/10/20 Concluded	Exame final da Especialidade de Oftalmologia (Título de especialista) Centro Hospitalar e Universitário de Coimbra EPE, Portugal	97/100
2008/04/01 - 2012/10/20 Concluded	Internato Complementar de Oftalmologia (Especialização pós-licenciatura) Major in Oftalmologia Centro Hospitalar e Universitário de Coimbra EPE, Portugal	97 (0-100)
2012/06/04 - 2012/06/04 Concluded	Data presentation and Manuscript Writing workshop (Outros) Major in Clinical Research Harvard Medical School, United States
2010/09/01 - 2010/11/30 Concluded	Fellowship (Outros) Major in Medical Retina and Uveitis Moorfields Eye Hospital NHS Foundation Trust, United Kingdom
2010/05/28 - 2010/06/30 Attended	Curso de formação profissional: SPSS Avançado (Outros) Major in Estatística Centro Hospitalar e Universitário de Coimbra EPE, Portugal
2009/12/14 - 2010/01/11 Concluded	Curso Básico de SPSS em ambiente windows-Módulo I (Outros) Major in Estatística Central de estudos de Medicina Geral e Familiar, Portugal
2007 - 2008 Attended	Internato Complementar de Cardiologia Pediátrica (Especialização pós-licenciatura) Major in Cardiologia Pediátrica Centro Hospitalar de Lisboa Central EPE, Portugal
2007/10 - 2007/10 Concluded	Exame de acesso ao Internato Complementar de Especialidade (Outros) Hospitais da Universidade de Coimbra, Portugal	86/100
2006 - 2006 Concluded	Internato Geral de Medicina (Especialização pós-licenciatura) Centro Hospitalar de Lisboa Central EPE, Portugal
1999/09 - 2005/06/29 Concluded	Medicina (Licenciatura) Universidade de Coimbra Faculdade de Medicina, Portugal	16 (0-20)
2003/09/15 - 2004/07/20 Concluded	Programa Socrates/ERASMUS (Outros) Major in Medicina Université Libre de Bruxelles, Belgium

Affiliation

Science

	Category Host institution	Employer
2008 - Current	Researcher (Research)	Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal

Teaching in Higher Education

	Category Host institution	Employer
2015/09 - 2016/06	Assistant (University Teacher)	Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
	Hospital de Sousa Martins, Portugal
2009 - 2011	Assistant (University Teacher)	Universidade de Coimbra Faculdade de Medicina, Portugal
	Hospitais da Universidade de Coimbra, Portugal

Other Careers

	Category Host institution	Employer
2018 - 2019	Assistente (Médica)	Centro Hospitalar do Baixo Vouga EPE, Portugal

2013 - 2017	Assistente (Médica)	Unidade Local de Saúde da Guarda EPE, Portugal

2008 - 2012	Interno (Médica)	Centro Hospitalar e Universitário de Coimbra EPE, Portugal

2006 - 2008	Interno (Médica)	Centro Hospitalar de Lisboa Central EPE, Portugal

Positions / Appointments

	Category Host institution	Employer
2020 - Current	Organic Unit Director	Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal

Others

	Category Host institution	Employer
2015 - Current	Project Coordinator and Medical Grader	Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal

Projects

Grant

	Designation	Funders
2023/09 - 2025/05	QUASAR - Efficacy and Safety of High Dose Aflibercept in Macular Edema Secondary to Retinal Vein Occlusion EU-CT number: 2022-502174-16-00 Principal investigator Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal	Bayer AG Ongoing
2022/03 - 2025	Retinal ischemia characterization in diabetes RICHARD NCT05112445 Principal investigator Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal	Boehringer Ingelheim AB Ongoing

Contract

	Designation	Funders
2020/12 - Current	A Phase 2 randomized, placebo-controlled, double-masked proof-of-concept and dose-finding study to investigate the efficacy and safety of runcaciguat (BAY 1101042) in patients with moderately severe to severe non-proliferative diabetic retinopathy BAY1101042_ 20739 NCT04265261 Technical development Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal	Bayer AG Ongoing
2020/10 - Current	RECOGNISED - Retinal and cognitive dysfunction in type 2 diabetes: unraveling the common pathways and identification of patients at risk of dementia. ECR-RET-2019-14 NCT04281186 Principal investigator Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal	Fundació Hospital Universitari Vall D’Hebron, VHIR Ongoing
2019/12 - Current	RECOGNISED - Retinal and cognitive dysfunction in type 2 diabetes: unraveling the common pathways and identification of patients at risk of dementia ECR-RET-2019-14 NCT04281186 Technical development Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal	Ongoing
2018/07 - Current	CORDIS - Characterization of Retinal vascular disease in eyes with mild to moderate NPDR in Diabetes type 2, using novel non-invasive Imaging methods, in a longitudinal, prospective and interventional clinical Study with 2 years of duration ClinicalTrials.gov Identifier: NCT03696810 Protocol CEC/194/18 Researcher Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal	Associação para a Inovação e Desenvolvimento da FCT Ongoing
2018/02 - Current	MACUSTAR / ECR-AMD-2017-13 - Development of novel clinical endpoints for interventional clinical trials with a regulatory and patient access intention in patients with intermediate age-related macular degeneration (AMD ClinicalTrials.gov: NCT03349801 Researcher Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal	European Union Ongoing
2023/04 - 2025/08	MEERKAT - A phase III, multicenter, randomized, double-masked, sham-controlled study to investigate the efficacy, safety, pharmacokinetics, and pharmacodynamics of RO7200220 administered intravitreally in patients with uveitic macular edema EU Trial Number: 2022-501793-19-00 Principal investigator Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal	F Hoffmann-La Roche AG Research and Development Division Ongoing
2018/07/01 - 2022/06/30	CORDIS PTDC/MEC-OFT/30375/2017 Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2018/10 - 2022	CORDIS - Characterization of Retinal vascular disease in eyes with mild to moderate NPDR in Diabetes type 2, using novel non-invasive Imaging methods, in a longitudinal, prospective and interventional clinical Study with 2 years of duration NCT03696810 CEC/194/18 Technical development Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal	Associação para a Inovação e Desenvolvimento da FCT
2012 - 2016	LUMINOUS - RFB002A2406 NCT01318941 Researcher	Concluded
2012 - 2015	EUROCONDOR / 4C-2011-02 - Neurodegeneration as an early event in the pathogenesis of DR: A trial to assess the efficacy of neuroprotective drugs administered topically to prevent or arrest DR. 4C-2011-02 Researcher Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal	European Union Concluded

Other

	Designation	Funders
2021/03 - Current	Characterization of Retinal disease progression in eyes with NPDR in diabetes Type 2 using non-invasive procedures CHART NCT04636307 Principal investigator Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal	Bayer Antwerpen NV Ongoing
2020 - Current	KALAHARI - A study to evaluate THR-149 treatment for diabetic macular oedema THR-149-002 EudraCT: 2019-001506-17 IND: 137669 Technical development Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal	Oxurion Ongoing
2019/09 - Current	PANDA KHB-1801 A Multicenter, Double Masked, Randomized, Dose-Ranging Trial to Evaluate the Efficacy and Safety of Conbercept Intravitreal Injection in Subjects with Neovascular Age-Related Macular Degeneration KHB-1801 Researcher Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal	Ongoing
2019/03 - Current	OPTIMUM LT / AC-058B303 - Multicenter, non-comparative extension to study AC-058B301, to investigate the long-term safety, tolerability, and control of disease of ponesimod 20 mg in subjects with relapsing multiple sclerosis. AC-058B303 ClinicalTrials.gov: NCT03232073 Researcher Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal	Actelion Clinical Research Inc
2016 - Current	A multi-site, open-label extension Trial of Oral RPC1063 in relapsing Multiple Sclerosis ClinicalTrials.gov Identifier: NCT02576717 Protocol RPC01-3001 Researcher Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal	Ongoing
2016 - Current	OPTIMUM - Multicenter, randomised, double-blind, parallel-group, active-controlled, superiority study to compare the efficacy and safety of ponesimod to teriflunomide in subjects with relapsing multiple sclerosis " ClinicalTrials.gov Identifier: NCT02425644" Protocol AC-058301 Researcher Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal	Ongoing
2015 - Current	IRISS - An open label, registry study of the safety of LUVIEN® 190 micrograms intravitreal implant in applicator ClinicalTrials.gov Identifier: NCT01998412 Protocol M-01-12-001 Researcher Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal	Ongoing
2015 - Current	AZURE - An open-label, randomized, active-controlled, parallel-group, Phase-3b study of the efficacy, safety, and tolerability of 2 mg aflibercept administered by intravitreal injections using two different treatment regimens to subjects with neovascular age-related macular degeneration (nAMD) ClinicalTrials.gov Identifier: NCT02540954 Protocol BAY 86-5321 / 16598 Researcher Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal	Ongoing
2015 - Current	EYEMARKER - Characterization of poential biomarkers of Eye Disease and Vision Loss ClinicalTrials.gov Identifier: NCT02500862 Protocol 4C-2015-08 Researcher Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal	Ongoing
2018 - 2022	Xplore / XBR1001 - Xplore: A Phase III Double-Blind, Parallel Group, Multicenter Study to Compare the Efficacy and Safety of Xlucane versus Lucentis® in Patients with Neovascular Age-Related Macular Degeneration. ClinicalTrials.gov: NCT03805100 XBR1001 Technical development Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal	Xbrane Biopharma
2020/06 - 2021	ReFineDR: Observational study of Routine ophthalmological examinations of patients included in the 2 Bayer sponsored phase 3 clinical trials FIDELIO and FIGARO to investigate the effect of Finerenone on delaying the progression of Diabetic Retinopathy NCT04477707 Technical development Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal	Ongoing
2018 - 2021	RHINE - A phase III, multicentre, randomized, double-masked, active comparator-controlled study to evaluate the efficacy and safety of RO6867461 in patients with diabetic macular edema ClinicalTrials.gov Identifier: NCT03622593 Protocol GR40398 Researcher Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal	Ongoing
2017 - 2021	PROGRESS – Progression of Diabetic Retinopathy. Identification of Signs and Surrogate outcomes ClinicalTrials.gov Identifier: NCT03010397 Protocol CEC/007/2016 Principal investigator Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal	Ongoing
2020/06 - 2020/12/05	Alimera_Protocol 01-20-005 - The New Day Study - A Randomized, Masked, Controlled Study of Intravitreal ILUVIEN ® Implant as Baseline Therapy in Patients with Early Diabetic Macular Edema (DME) Protocol 01-20-005 NCT04469595 Technical development Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal	Alimera Sciences Inc Ongoing
2018 - 2020	KESTREL - A two-year, three-arm, randomized, double-masked, multicentre, phase III study assessing the efficacy and safety of brolucizumab versus aflibercept in adult patients with visual impairment due to diabetic macular edema ClinicalTrials.gov Identifier: NCT03481634 Protocol CRTH258B2301 Researcher Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal
2017/12 - 2019/11	THR-317-002 - A study to evaluate the efficacy and safety of intravitreal THR-317 when administered alone or in combination with Lucentis®, in DME patients with a poor or no response to anti-VEGF treatment. ClinicalTrials.gov: NCT03410693 Technical development Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal	Oxurion Concluded
2016 - 2019	VIOLET/BAY 86-5321 / 17613 - An open-label, randomized, active-controlled, parallel-group, Phase-3b study of the efficacy, safety, and tolerability of three different treatment regimens of 2 mg aflibercept administered by intravitreal injections to subjects with diabetic macular edema(DME) ClinicalTrials.gov Identifier: NCT02818998 Protocol BAY 86-5321 / 17613 Technical development Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal	Concluded
2017/12 - 2018/10	THR-317-001 - Additional OCT Analysis ClinicalTrials.gov: NCT03071068 Technical development Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal	ThromboGenics NV Concluded
2016/08 - 2018/10	THR-317-001 - A Phase 2, single-masked, multicentre study to evaluate the safety and efficacy of 2 dose levels of THR317 for the treatment of diabetic macular oedema (DME). ClinicalTrials.gov: NCT03071068 Technical development Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal	ThromboGenics NV Concluded
2018 - 2018	A randomized , open label, multicenter Phase 2/3 study to evaluate the efficacy and safety of rogaratinib (BAY 1163877) compared to chemotherapy in patients with FGFR-positive locally advanced or metastatic urothelial carcinoma who have received prior platinum-containing chemotherapy ClinicalTrials.gov Identifier: NCT03410693 Protocol BAY 1163877/17403 Researcher Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal	Cancelled
2015 - 2018	ATLANTIC - A randomized, double-masked, sham-controlled phase 4 study of the efficacy, safety, and tolerability of intravitreal aflibercept monotherapy compared to aflibercept with adjunctive photodynamic therapy in patients with polypoidal choroidal vasculopathy ClinicalTrials.gov Identifier: NCT02495181 Protocol ECR-AMD-2015-09 Researcher Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal	Concluded
2015 - 2018	HARRIER - A Two-Year, Randomized, Double-Masked, Multicenter, Two-Arm Study Comparing the Efficacy and Safety of RTH258 6 mg Versus Aflibercept in Subjects with Neovascular Age-Related Macular Degeneration ClinicalTrials.gov Identifier: NCT02434328 Protocol RTH258-C002 Researcher Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal	Concluded
2015/04 - 2017/11	AQUA/BAY 86-5321 /17850 - Open-label Phase-4 study to examine the change of vision-related quality of life in subjects with diabetic macular edema (DME) during treatment with intravitreal injections of 2 mg aflibercept according to EU label for the first year of treatment. ClinicalTrials.gov: NCT02581995 BAY 86-5321 /17850 Technical development Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal	Bayer AG Concluded
2017 - 2017	OMASPECT - A multi-center, open label extension study to evaluate the long-term safety and tolerability of Lampalizumab in patients with Geographic atrophy secondary to Age-related Macular Degeneration ClinicalTrials.gov Identifier: NCT02745119 Protocol GX30191 Researcher Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal	Concluded
2016 - 2017	AMDIncidencePT - Five-year incidence of Age-related Macular Degeneration in the central region of Portugal " ClinicalTrials.gov Identifier: NCT02748824" Protocol 4C-2016-09 Researcher Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal	Concluded
2016 - 2017	A randomized, double-masked, placebo-controlled exploratory study to evaluate pharmacodynamics, safety and tolerability of orally administered BI 1026706 for 12 weeks in patients with mild visual impairment due to center-involved diabetic macular edema (DME) ClinicalTrials.gov Identifier: NCT02732951 Protocol BI 1320.22 Researcher Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal	Boehringer Ingelheim Chemicals Inc Concluded
2015 - 2017	SPECTRI - A phase III, multicenter, randomized, double-masked, sham-controlled study to assess the efficacy and safety of lampalizumab administered intravitreally to patients with geographic atrophy secondary to age-related macular degeneration ClinicalTrials.gov Identifier: NCT02247531 Protocol GX29185 Researcher Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal	Concluded
2015 - 2017	SUNBEAM - A phase III, multicenter, randomized, double-blind, double-dummy, active controlled, parallel group study to evaluate the efficacy and safety of RPC1063 administered orally to relapsing multiple sclerosis patients ClinicalTrials.gov Identifier: NCT02294058 Protocol RPC01-301 Researcher Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal	Concluded
2015 - 2017	THEA-UNAV1/14 - An Interventional, multicentre, randomized study of nutritional supplements in unilateral wet AMD Protocol THEA-UNAV1/14 Researcher Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal	Concluded
2015 - 2017	Genotypic and Phenotypic characterization of retinal angiomatous proliferation (RAP) lesions Protocol CEC 006/2015 Researcher Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal	Concluded
2014 - 2017	EPOCH - A Randomized, Placebo Controlled, Parallel-Group, Double Blind Efficacy and Safety Trial of MK-8931 in Subjects with Mild to Moderate Alzheimer’s Disease ClinicalTrials.gov Identifier: NCT01739348 Researcher Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal	Concluded
2014 - 2017	SALT - Study to compare efficacy of 0.5 mg ranibizumab PRN versus 2 mg aflibercept bimonthly intravitreal injections on retinal thickness stability till month 6 of treatment and explore functional outcomes up to month 12 in patients with neovascular (wet) age-related macular degeneration (AMD) ClinicalTrials.gov Identifier: NCT01958918 Protocol CRFB002ADE23 Researcher Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal	Concluded
2014 - 2017	FOVISTA - Trial to establish safety and efficacy of intravitreous FOVISTA TM (Anti PDGF-B Pegylated Aptamer) administered in combination with either Avastin® or Eylea® compared to Avastin® or Eylea® Monotherapy in subjects with subfoveal neovascular Age-Related Macular Degeneration ClinicalTrials.gov Identifier: NCT01940887 Protocol OPH1004 Researcher Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal	Concluded
2015 - 2016	IN0654 - Metabolomics, Genetics and Environment – a novel integrative approach to Age-Related Macular Degeneration IN0654 Researcher Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal	Concluded
2015 - 2016	OCTA - Clinical evaluation of noninvasive OCT Angiography using a Zeiss OCT Prototype to compare to fluorescein angiography ClinicalTrials.gov Identifier: NCT02391558 Protocol 4C-2015-07 Researcher Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal	Concluded
2014 - 2016	PROTEUS - Prospective, randomized, multicentre, open label, phase II / III study to assess efficacy and safety of ranibizumab 0.5 mg intravitreal injections plus panretinal photocoagulation (PRP) versusPRP in monotherapy in the treatment of subjects with high risk proliferative diabetic retinopathy ClinicalTrials.gov Identifier: NCT01941329 Protocol ECR-RET-2013-05 Researcher Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal	Concluded
2014 - 2016	ARTES - A Collaborative Retrospective Trial on the Efficacy and Safety of intravitreal dexamethasone implant (Ozurdex) in patients with Diabetic Macular Edema (DME). The European DME Registy Study ClinicalTrials.gov Identifier: NCT02121197 Protocol ECR-RET-2014-07 Researcher Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal	Concluded
2013 - 2016	CHARTRES - Characterization of Eyes with Diabetic Macular Edema that show different Treatment Response to Intravitreal anti-VEGF ClinicalTrials.gov Identifier: NCT01947881 Protocol 4C-2013-05 Researcher Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal	Concluded
2011 - 2016	A follow-up study evaluating the long-term safety of lacosamide (200 to 600mg/day) in comparison with carbamazepine (400 to 1200mg/day), used as monotherapy in subjects with partial-onset or generalized tonic-clonic seizures =16 years of age coming from the SP0993 study ClinicalTrials.gov Identifier: NCT01465997 Protocol SP0994 Researcher Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal	Concluded
2014 - 2015	JETREA - Assessment of Anatomical and Functional Outcomes in Patients Treated with Ocriplasmin for Vitreomacular Traction/Symptomatic Vitreomacular Adhesion (VMT/sVMA) ClinicalTrials.gov Identifier: NCT02035748 Protocol M-13-056 Researcher Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal	Concluded
2012 - 2015	C-Tracer - Biomarkers of Diabetic Retinopathy Progression ClinicalTrials.gov Identifier: NCT01607190 Protocol 4C-2012-02 Researcher Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal	Concluded
2011 - 2015	BRIGHTER - A phase IIIb study assessing efficacy and safety of PRN dosing regimen with 0,5mg ranibizumab monotheraphy or with adjunctive laser photocoagulation in comparison to laser photocoagulation in patients with visual impairment due to macular edema secondary to branch vein occlusion (BRVO) ClinicalTrials.gov Identifier: NCT01599650 Protocol CRFB002E2402 Researcher Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal	Concluded
2014 - 2014	SPORT - Intraocular pressure and tolerability Study of Preservative Free Bimatoprost 0,03% Unit Dose (BUDPF) or preservative free Latanoprost 0.005% Unit Dose (LUDPF) (Monoprost) in patients with Ocular hypertension or glaucoma ClinicalTrials.gov Identifier: NCT01975714 Protocol ECR-GLC-2013-06 Researcher Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal	Concluded
2012 - 2014	CRYSTAL - A phase IIIb study assessing efficacy and safety of PRN dosing regimen with 0.5-mg ranibizumab monotherapy in patients with visual impairment due to macular edema secondary to central retinal vein occlusion (CRVO) ClinicalTrials.gov Identifier: NCT01535261 Protocol CRFB002E2401 Researcher Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal	Concluded
2013 - 2013	BENEFIT - Long-term, follow-up study (16401) of the BENEFIT (304747),BENEFIT Follow-up (305207) Studies and BENEFIT Extension (311129) Study to further evaluate theprogress of patients with first demyelinating event suggestive of multiple sclerosis ClinicalTrials.gov Identifier: NCT01795872 Researcher Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal	Bayer AG Concluded

Outputs

Publications

Book chapter	CTeixeira. "Thrombocytopenias". In Portuguese Ophthalmology Society and Portuguese Retina Study Group Manual 2023 - Fundus Manifestations of Systemic Diseases. Sociedade Portuguesa Oftalmologia and Grupo de Estudos de Retina, 2023. Published • https://doi.org/10.48560/978-989-33-4919-9 C Teixeira. "Diabetes Mellitus". In Fundus Manifestations of Systemic Diseases. 2023. Published • 10.48560/978-989-33-4919-9 Marques, Inês P; Santos, Ana Rita; Lopes, Marta. "Adaptometria". In Meios Complementares de Diagnóstico em Oftalmologia. Portugal: Sociedade Portuguesa de Oftalmologia, 2020. Published Marques, I.P.; Mendes, L.; Cunha-Vaz, J.. "Noninvasive Multimodal Imaging of Diabetic Retinopathy". In Imaging Techniques. ESASO Course Series, edited by Cunha-Vaz, J.; Koh, A., 88-101. Basel: Karger, 2018. Published Marques, I.P.; Ribeiro, L.. "III. Retinopatia Diabética: Fisiopatologia, Epidemiologia e Classificação". In Manual de Retina, edited by Silva, R.; Farah, M.E., 105-110. Lisboa, Portugal: LIDEL, 2016. Published
Conference poster	Marques, Inês P. "Baseline characterization of retinal vascular disease in eyes with mild to moderate non proliferative diabetic retinopathy in diabetes type 2, using novel non-invasive imaging methods, in a longitudinal prospective and interventional 2-year clinical study (CORDIS)". Paper presented in EASDec Annual Meeting 2020, 2020. Sherlaw, CA; Karandikar, S; Rweyemamu, J. "Different retinopathy phenotypes in diabetes type 2 show different five years risks for development of DME and PDR". Paper presented in 5ª Reunião Científica Internacional do GER, 2020. Marques, Inês P; Durbin, M.K.. "Characterization of the initial stages of diabetic retinal disease using OCT and OCTA". Paper presented in Association for Research in Vision and Ophthalmology Annual Meeting 2019, 2019. Marques, Inês P. "Five year progression to vision threatening complications of mild NPDR in patients with diabetes type 2". Paper presented in ARVO 2019, 2019. Marques, Inês P; Durbin, M.K.; Mendes, Luís; Santos, Torcato; Neves, Catarina; Santos, Ana Rita; Alves, Dalila Gil ; Cunha-Vaz, José. "Characterization of the initial stages of diabetic retinal disease using optical coherence tomography (OCT) and OCT Angiography (OCTA)". Paper presented in ARVO Annual Meeting 2018, 2018. Marques, Inês P; Santos, Torcato; Cunha-Vaz, José. "Methods for quantification of retinal microvascular density in CIRRUS AngioPlex OCT Angiography (OCTA) Images". Paper presented in 26th EASDec Annual Meeting, 2016. Marques, Inês P. "Real-World outcomes of anti-VEGF treatment for retinal vein occlusion (RVO) in Portugal". Paper presented in Reunião Científica Internacional do GER 2016, 2016. Marques, Inês P; Cachulo, M.L.; Lains, I.; Figueira, J.; Lobo, C.; Nunes, S.; Costa, M.; et al. "Prevalence of Age-related Macular Degeneration in Portugal: the Coimbra Eye Study – Report 1". Paper presented in ARVO 2014, 2014. Pires, I; Marques, I; Gregório, T; Cachulo, ML; Santos, AR; Melo, P; Fonseca, P; Silva, R. "Intravitreal Ranibizumab with Photodynamic Therapy for the Treatment of Symptomatic Polypoidal Choroidal Vasculopathy". Paper presented in 12th Euretina Congress, 2012. Marques, Inês P; Oliveira, R.; Russo, A.; Figueira, J.; Cachulo, M.L.; Pires, I.; Silva, R.. "Retinopatia de Valsalva". Paper presented in 54º Congresso Português de Oftalmologia, 2011. Marques, Inês P; Gregório, T.; Farinha, C.; Rosa, A.; Quadrado, M.J.. "Endotelite corneana herpética, a propósito de um caso clínico". Paper presented in VII Reunião do Hospital de Santa Maria da Feira, 2011. Marques, I; Oliveira, R; Russo, A; Figueira, J; Cachulo, ML; Pires, I; Silva, R. "Retinopatia de Valsava.". Paper presented in 54º Congresso Português de Oftalmologia. Vilamoura, 1-3 Dezembro 2011, 2011. Marques, I; Gregório, T; Farinha, CL; Rosa, AM; Quadrado, MJ; Murta, JN. "Endotelite corneana herpética". Paper presented in Cornea 2011, 2011. Gregório, T; Farinha, CL; Marques, I; Rosa, AM; Leal, S; Quadrado, MJ; Murta, JN. "Tratamento de queratite por acanthamoeba com crosslinking corneano - relato de 2 casos clínicos". Paper presented in Cornea 2011, 2011. Marques, Inês P; Pereira, H.; Vasconcelos, H.; Rosa, A.; Quadrado, M.J.; Murta, J.. "Quistos epiteliais de inclusão após cirurgias múltiplas- Caso clínico". Paper presented in 53º Congresso Português de Oftalmologia, 2010. Marques, Inês P; Rosa, A.; Cardoso, J.; Pereira, H.; Almeida, M.; Quadrado, M.J.; Murta, J.N.. "Pregueamento da Descemet em DALK". Paper presented in 53º Congresso Português de Oftalmologia, 2010. Marques, I; Pereira, H; Vasconcelos, H; Rosa, AM; Quadrado, MJ; Murta, JN. "Quistos epiteliais de inclusão após cirurgias múltiplas". Paper presented in 53º Congresso Português de Oftalmologia, 2010. Marques, Inês P; Pires, I.; Cachulo, M.L.; Santos, A.R.; Melo, P.; Figueira, J.; Silva, R.. "Múltiple Evanescent White Dot Syndrome- Case report". Paper presented in 52º Congresso Português de Oftalmologia, 2009.
Journal article	Santos, Ana Rita; Almeida, Ana Catarina; Rocha, Ana Cláudia; Reste-Ferreira, Débora; Marques, Inês Pereira; Cunha-Vaz Martinho, António; Mendes, Luís; et al. "Central and Peripheral Involvement of the Retina in the Initial Stages of Diabetic Retinopathy". Retina (2023): http://dx.doi.org/10.1097/iae.0000000000004021. 10.1097/iae.0000000000004021 Reste-Ferreira, Débora; Marques, Inês Pereira; Santos, Torcato; Ribeiro, Maria Luísa; Mendes, Luís; Santos, Ana Rita; Lobo, Conceição; Cunha-Vaz, José. "Retinal neurodegeneration in eyes with NPDR risk phenotypes: A two-year longitudinal study". Acta Ophthalmologica (2023): http://dx.doi.org/10.1111/aos.15787. 10.1111/aos.15787 Santos, Torcato; Santos, Ana Rita; Almeida, Ana Catarina; Rocha, Ana Cláudia; Reste-Ferreira, Débora; Marques, Inês Pereira; Cunha-Vaz Martinho, António; et al. "Retinal Capillary Nonperfusion in Preclinical Diabetic Retinopathy". Ophthalmic Research 66 1 (2023): 1327-1334. http://dx.doi.org/10.1159/000534553. 10.1159/000534553 Marques, Inês P.; Ribeiro, Maria L.; Santos, Torcato P.; Mendes, Luis G.; Reste-Ferreira, Débora; Santos, Ana R.; Lobo, Conceição L.; Cunha-Vaz, José G.. "Different Risk Profiles for Progression of Nonproliferative Diabetic Retinopathy: A 2-Year Study". Ophthalmology and Therapy 12 1 (2022): 485-500. http://dx.doi.org/10.1007/s40123-022-00623-7. Published • 10.1007/s40123-022-00623-7 Marques, Inês P.; Ribeiro, Maria L.; Santos, Torcato P.; Mendes, Luis G.; Reste-Ferreira, Débora; Santos, Ana R.; Lobo, Conceição L.; Cunha-Vaz, José G.. "Different Risk Profiles for Progression of Nonproliferative Diabetic Retinopathy: A 2-Year Study". Ophthalmology and Therapy 12 1 (2022): 485-500. http://dx.doi.org/10.1007/s40123-022-00623-7. 10.1007/s40123-022-00623-7 Ribeiro, Luísa; Marques, Inês P.; Santos, Torcato; Carvalho, Sara; Santos, Ana R.; Mendes, Luís; Lobo, Conceição; Cunha-Vaz, José. "Characterization of two-year progression of different phenotypes of nonproliferative diabetic retinopathy". Ophthalmic Research (2022): http://dx.doi.org/10.1159/000526370. 10.1159/000526370 Lobo, Conceição; Santos, Torcato; Marques, Inês P.; Madeira, Maria H.; Santos, Ana Rita; Figueira, João; Cunha-Vaz, José. "Characterisation of progression of macular oedema in the initial stages of diabetic retinopathy: a 3-year longitudinal study". Eye (2022): http://dx.doi.org/10.1038/s41433-022-01937-3. Published • 10.1038/s41433-022-01937-3 Madeira, Maria H.; Marques, Inês P.; Ferreira, Sónia; Tavares, Diana; Santos, Torcato; Santos, Ana Rita; Figueira, João; Lobo, Conceição; Cunha-Vaz, José. "Retinal Neurodegeneration in Different Risk Phenotypes of Diabetic Retinal Disease". Frontiers in Neuroscience 15 (2021): http://dx.doi.org/10.3389/fnins.2021.800004. 10.3389/fnins.2021.800004 Ribeiro, Luísa; Marques, Inês P.; Coimbra, Rita; Santos, Torcato; Madeira, Maria H.; Santos, Ana Rita; Barreto, Patrícia; Lobo, Conceição; Cunha-Vaz, José. "Characterization of One-Year Progression of Risk Phenotypes of Diabetic Retinopathy". Ophthalmology and Therapy 11 1 (2021): 333-345. http://dx.doi.org/10.1007/s40123-021-00437-z. 10.1007/s40123-021-00437-z Vujosevic, Stela; Cunha-Vaz, José; Figueira, João; Löwenstein, Anat; Midena, Edoardo; Parravano, Mariacristina; Scanlon, Peter Henry; et al. "Standardisation of Optical Coherence Tomography Angiography Imaging Biomarkers in Diabetic Retinal Disease". Ophthalmic Research (2021): http://dx.doi.org/10.1159/000518620. 10.1159/000518620 Marques, Inês P; Santos, Ana Rita. "Microaneurysm Turnover in eyes with mild nonproliferative diabetic retinopathy is associated with progression and development of sight-threatening complications: a 5-year longitudinal study". Investigative Ophthalmology & Visual Science 62 8 (2021): 1098. Published Marques, Inês P; Ribeiro, Maria Luisa; Santos, Torcato; Cunha-Vaz, José; Figueira, João; Ana Rita Santos. "Characterization of one-year progression in risk phenotypes of diabetic retinopathy". Investigative Ophthalmology & Visual Science 62 8 (2021): 1056. Published Marques, Inês P; Lobo, Conceição; Ribeiro, Maria Luisa; Cunha-Vaz, José. "Characterization of risk phenotypes of type 2 diabetes nonproliferative retinopathy". Investigative Ophthalmology & Visual Science 62 8 (2021): 1061. Published Marques, Inês P; Tavares, Diana; Madeira, Maria Helena; Santos, Torcato; Santos, Ana Rita. "Association between visual acuity loss and disease pathways in the initial stages of nonproliferative retinopathy in type 2 diabetes". OPEN ACCESS ARVO Annual Meeting Abstract \| June 2021 Association between visual acuity loss and disease pathways in the initial stages of nonproliferative retinopathy in type 2 diabetes Diana Tavares; Inês Marques; Maria Helena Madeira; Ana Rita Santos; Torcato Santos; Joao Figueira; Conceicão F Lobo; Jose G Cunha-Vaz Author Affiliations & Notes Investigative Ophthalmology & Visual Science 62 8 (2021): 1062. Published Marques, Inês P.; Kubach, Sophie; Santos, Torcato; Mendes, Luís; Madeira, Maria H.; de Sisternes, Luis; Tavares, Diana; et al. "Optical Coherence Tomography Angiography Metrics Monitor Severity Progression of Diabetic Retinopathy—3-Year Longitudinal Study". Journal of Clinical Medicine 10 11 (2021): 2296. http://dx.doi.org/10.3390/jcm10112296. Published • 10.3390/jcm10112296 Santos, Ana Rita; Mendes, Luis; Madeira, Maria Helena; Marques, Ines P.; Tavares, Diana; Figueira, João; Lobo, Conceição; Cunha-Vaz, José. "Microaneurysm Turnover in Mild Non-Proliferative Diabetic Retinopathy is Associated with Progression and Development of Vision-Threatening Complications: A 5-Year Longitudinal Study". Journal of Clinical Medicine 10 10 (2021): 2142. http://dx.doi.org/10.3390/jcm10102142. 10.3390/jcm10102142 Ana Rita Santos; Luis Mendes; Madeira, M.H.; Inês Marques; Diana Tavares; João P Figueira; Conceição Lobo; José Cunha-Vaz. "Microaneurysm Turnover in Mild Non-Proliferative Diabetic Retinopathy is Associated with Progression and Development of Vision-Threatening Complications: A 5-Year Longitudinal Study". Journal of Clinical Medicine (2021): https://www.mdpi.com/2077-0383/10/10/2142. 10.3390/jcm10102142 Marques, Inês P; Kubach, Sophie; Santos, Torcato; Mendes, Luis; Madeira, Maria H; Sisternes, Luis de; Santos, Ana Rita; et al. "OCTA metrics predict severity progression of Diabetic Retinopathy – 3-year longitudinal study". RETINA (2021): Submitted Marques, Inês P. "Microaneurysm Turnover in mild Non-Proliferative Diabetic Retinopathy is Associated with Progression and Development of Vision-threatening Complications: a 5-year longitudinal study". MDPI (2021): Accepted Vujosevic, Stela; Vaz, José Cunha; Figueira, João; Löwenstein, Anat; Midena, Edoardo; Parravano, Mariacristina; Scanlon, Peter Henry; et al. "Standardization of Optical Coherence Tomography Angiography Imaging Biomarkers in Diabetic Retinal Disease". (2021): http://hdl.handle.net/10316/96849. https://doi.org/10.1159/000518620 Santos, Torcato; Warren, Lewis H; Santos, Ana Rita; Marques, Inês Pereira; Kubach, Sophie; Mendes, Luís G; Sisternes, Luis de; et al. "Swept-source OCTA quantification of capillary closure predicts ETDRS severity staging of NPDR". British Journal of Ophthalmology (2020): bjophthalmol-2020. http://dx.doi.org/10.1136/bjophthalmol-2020-317890. Published • 10.1136/bjophthalmol-2020-317890 Martinho, António C.-V.; Marques, Inês P.; Messias, Ana L.; Santos, Torcato; Madeira, Maria H.; Sousa, David C.; Lobo, Conceição; Cunha-Vaz, José. "Ocular and Systemic Risk Markers for Development of Macular Edema and Proliferative Retinopathy in Type 2 Diabetes: A 5-Year Longitudinal Study". Diabetes Care 44 1 (2020): e12-e14. http://dx.doi.org/10.2337/dc20-1125. 10.2337/dc20-1125 Marques, Inês P.; Madeira, Maria H.; Messias, Ana L.; Martinho, António C.-V.; Santos, Torcato; Sousa, David C.; Figueira, João; Cunha-Vaz, José. "Different retinopathy phenotypes in type 2 diabetes predict retinopathy progression". Acta Diabetologica (2020): http://dx.doi.org/10.1007/s00592-020-01602-9. Published • 10.1007/s00592-020-01602-9 Marques, Ines P.; Madeira, Maria H.; Messias, Ana L.; Santos, Torcato; Martinho, António C-V.; Figueira, João; Cunha-Vaz, José. "Retinopathy Phenotypes in Type 2 Diabetes with Different Risks for Macular Edema and Proliferative Retinopathy". Journal of Clinical Medicine 9 5 (2020): 1433. http://dx.doi.org/10.3390/jcm9051433. 10.3390/jcm9051433 Marques, I.P.; Alves, D.; Santos, T.; Mendes, L.; Lobo, C.; Santos, A.R.; Durbin, M.; Cunha-Vaz, J.. "Characterization of Disease Progression in the Initial Stages of Retinopathy in Type 2 Diabetes: A 2-Year Longitudinal Study". Investigative Opthalmology & Visual Science 61 3 (2020): 20. http://dx.doi.org/10.1167/iovs.61.3.20. 10.1167/iovs.61.3.20 Ros Forteza, F.J.; Pereira Marques, I.. "Hipertensión intracraneal inducida por minociclina en mujer portadora de dispositivo intrauterino de levonorgestrel". Neurología 34 8 (2019): 551-553. http://dx.doi.org/10.1016/j.nrl.2016.11.012. 10.1016/j.nrl.2016.11.012 Marques, Inês P; Santos, Torcato; Santos, Ana Rita; Alves, Dalila Gil ; Lobo, Conceição; Cunha-Vaz, José. "Characterization of macular edema in the initial stages of diabetic retinopathy". Investigative Opthalmology & Visual Science 60 11 (2019): Published Marques, Inês P. "Automatic quantification of focal capillary dropout for identification of ischemia in patients with DR". Investigative Ophthalmology & Visual Science 60 11 (2019): Published Marques, Inês P; Mendes, Luis; Santos, Torcato; Alves, Dalila Gil ; Durbin, M.K.; Cunha-Vaz, José. "Changes in vessel density in the initial stages of retinopathy in diabetes type 2. A two-year longitudinal study". Investigative Opthalmology & Visual Science 60 9 (2019): 160-160. Published Santos, A.R.; Santos, T.; Alves, D.; Marques, I.P.; Lobo, C.; Cunha-Vaz, J.. "Characterization of Initial Stages of Diabetic Macular Edema". Ophthalmic Research 62 4 (2019): 203-210. http://www.scopus.com/inward/record.url?eid=2-s2.0-85064904870&partnerID=MN8TOARS. 10.1159/000499117 Marques, Inês P; Coelho, Dalila; Santos, Torcato; Mendes, Luis. "Multimodal imaging of the initial stages of diabetic retinopathy. Different disease pathways in different patients". Investigative Ophthalmology & Visual Science 60 3022 (2019): Published Marques, I.P.; Alves, D.; Santos, T.; Mendes, L.; Santos, A.R.; Lobo, C.; Durbin, M.; Cunha-Vaz, J.. "Multimodal imaging of the initial stages of diabetic retinopathy: Different disease pathways in different patients". Diabetes 68 3 (2019): 648-653. http://www.scopus.com/inward/record.url?eid=2-s2.0-85061915847&partnerID=MN8TOARS. 10.2337/db18-1077 Marques, Inês P. "Characterization of the initial stages of diabetic retinal disease using optical coherence tomography (OCT) and OCT Angiography (OCTA)". Investigative Ophthalmology & Visual Science 59 9 (2018): Published Marques, Inês P; Cunha-Vaz, J.; Santos, T.; Alves, D.; Neves, C.; Soares, M.; Lobo, C.. "Agreement between OCT-Leakage and Fluorescein Angiography to identify sites of alteration of the Blood-Retinal Barrier in Diabetes". Investigative Ophthalmology & Visual Science 58 8 (2017): 395-403. http://www.scopus.com/inward/record.url?eid=2-s2.0-85055228650&partnerID=MN8TOARS. Published • 10.1016/j.oret.2017.02.002 Vaz-Pereira, S.; Marques, I.P.; Matias, J.; Mira, F.; Ribeiro, L.; Flores, R.. "Real-world outcomes of anti-VEGF treatment for retinal vein occlusion in portugal". European Journal of Ophthalmology 27 6 (2017): 756-761. http://www.scopus.com/inward/record.url?eid=2-s2.0-85031856022&partnerID=MN8TOARS. 10.5301/ejo.5000943 Farinha, C.; Santos, T.; Marques, I.P.; Marques, J.P.; Ribeiro, L.; Figueira, J.; Silva, R.; Cunha-Vaz, J.. "OCT-Leakage Mapping: A New Automated Method of OCT Data Analysis to Identify and Locate Abnormal Fluid in Retinal Edema". Ophthalmology Retina 1 6 (2017): 486-496. http://www.scopus.com/inward/record.url?eid=2-s2.0-85057434808&partnerID=MN8TOARS. 10.1016/j.oret.2017.03.004 Vaz-Pereira, S.; Marques, I.P.; Flores, R.. "Author’s reply to comments to: Real-world outcomes of anti-VEGF treatment for retinal vein occlusion in portugal". European Journal of Ophthalmology 27 6 (2017): 756-761. http://www.scopus.com/inward/record.url?eid=2-s2.0-85034982834&partnerID=MN8TOARS. Published • 10.5301/ejo.5001015 Soares, M.; Neves, C.; Marques, I.P.; Pires, I.; Schwartz, C.; Costa, M.A.; Santos, T.; Durbin, M.; Cunha-Vaz, J.. "Comparison of diabetic retinopathy classification using fluorescein angiography and optical coherence tomography angiography". British Journal of Ophthalmology 101 1 (2017): 62-68. http://www.scopus.com/inward/record.url?eid=2-s2.0-85006035915&partnerID=MN8TOARS. 10.1136/bjophthalmol-2016-309424 Marques, Inês P; Coelho, Dalila. "Agreement between OCT-Leakage and Fluorescein Angiography to identify sites of alteration of the Blood-Retinal Barrier in Diabetes". Investigative Ophthalmology & Visual Science 58 1654 (2017): Published Cunha-Vaz, J.; Santos, T.; Ribeiro, L.; Alves, D.; Marques, I.; Goldberg, M.. "OCT-leakage: A new method to identify and locate abnormal fluid accumulation in diabetic retinal edema". Investigative Ophthalmology and Visual Science 57 15 (2016): 6776-6783. http://www.scopus.com/inward/record.url?eid=2-s2.0-85006698962&partnerID=MN8TOARS. 10.1167/iovs.16-19999 Rosa, A.M.; Silva, M.F.; Quadrado, M.J.; Costa, E.; Marques, I.; Neto Murta, J.. "Femtosecond laser and microkeratome-assisted Descemet stripping endothelial keratoplasty: First clinical results". British Journal of Ophthalmology 97 9 (2013): 1104-1107. http://www.scopus.com/inward/record.url?eid=2-s2.0-84882238090&partnerID=MN8TOARS. 10.1136/bjophthalmol-2012-302378 Vasconcelos, H.; Marques, I.; Santos, A.R.; Melo, P.; Pires, I.; Figueira, J.; De Abreu, J.F.; Cachulo, M.L.; Silva, R.. "Long-term chorioretinal changes after photodynamic therapy for chronic central serous chorioretinopathy". Graefe's Archive for Clinical and Experimental Ophthalmology 251 7 (2013): 1697-1705. http://www.scopus.com/inward/record.url?eid=2-s2.0-84879211300&partnerID=MN8TOARS. 10.1007/s00417-013-2270-2 Marques, I.P.; Fonseca, P.; Luz Cachulo, M.; Pires, I.; Figueira, J.; Faria De Abreu, J.R.; Silva, R.. "Treatment of exudative age-related macular degeneration with intravitreal ranibizumab in clinical practice: A 3-year follow-up". Ophthalmologica 229 3 (2013): 158-167. http://www.scopus.com/inward/record.url?eid=2-s2.0-84876490799&partnerID=MN8TOARS. 10.1159/000343709 Marques, I.P.; Mira, J.; Cardoso, J.; Pereira, H.; Ribeiro, M.; Rego, M.; Wolf, C.; et al. "Prophylactic intracameral moxifloxacin (0.5% vs 0.25%) and cefuroxime in modern cataract surgery - Comparative study: preliminar results". Oftalmologia 36 2 (2012): 123-132. Franqueira, N.; Cachulo, M.L.; Pires, I.; Fonseca, P.; Marques, I.; Figueira, J.; Silva, R.. "Long-term follow-up of myopic choroidal neovascularization treated with ranibizumab". Ophthalmologica 227 1 (2011): 39-44. http://www.scopus.com/inward/record.url?eid=2-s2.0-84155170752&partnerID=MN8TOARS. 10.1159/000333213 Rosa, A.M.; Cardoso, J.; Vasconcelos, H.; Ribeiro, M.; Marques, Inês P; Henriques, J.; Quadrado, M.J.; Murta, J.. "Tratamento do Queratocone com Implante de Anéis Intra-Estromais por Laser Femtosegundo – Resultados de Acordo com a Nova Classificação SAANA". Oftalmologia 35 3 (2011): 253-258. Rosa, A.; Quadrado, M.J.; Ferrão, J.; Marques, Inês P; Pereira, H.; Costa, E.; Murta, J.. "Ocular Manifestations of Type I Family Amyloid Polyneuropathy in patients undergoing liver transplantation". Experientia Ophthalmologica 33 (2009): 177-183. Costa, E.; Marques, Inês P; Cruz, M.; Travassos, A.S.; Pereira, H.; Quadrado, M.J.; Murta, J.. "Confocal microscopy in the diagnostic of corneal infections". Experientia Oftalmologica 35 (2009): 77-83. Rosa, AM; Quadrado, MJ; Ferrão, J; Marques, I; Pereira, H; Costa, E; Murta, JN. "Manifestações oculares de polineuropatia amiloidótica familiar tipo I em doentes submetidos a transplante hepático". Oftalmologia 33 3 (2009): 177-183. Published
Newsletter article	"Regresso às aulas - regresso ao computador!!!", Suplemento especial Saúde do Jornal dos Bancários, 2021
Newspaper article	Marques, Inês P; Madeira, Maria Helena; Santos, Torcato; Santos, Ana Rita; Tavares, Diana; Figueira, João; Lobo, Conceição; Cunha-Vaz, José. "Retinal neurodegeneration in type 2 diabetic individuals with mild retinopathy is independent of retinopathy severity progression: a 5-year longitudinal study", Investigative Ophthalmology & Visual Science, 2021, 62 Marques, Inês P; Santos, Ana Rita; Santos, Torcato; Kubach, Sophie; de Sisternes, Luis; Lewis, Warren; Durbin, Mary K.; Cunha-Vaz, José. "Degree and Location of Retinal Capillary Closure Indicate ETDRS grading of Non Proliferative Diabetic Retinopathy", Investigative Ophthalmology & Visual Science, 2021, 62 Marques, Inês P; Mendes, Luis; de Sisternes, Luis; Madeira, Maria H; Santos, Torcato; Lewis, Warren; Durbin, Mary K.; Cunha-Vaz, José. "Comparison of different methods for the identification of capillary closure in diabetics retinopathy using OCTA", Investigative Ophthalmology & Visual Science, 2021, 62
Thesis / Dissertation	Marques, Inês P. "PROGRESS – Progression of Diabetic Retinopathy. Identification of Signs and Surrogate outcomes". PhD, Universidade de Coimbra Faculdade de Medicina, 2021. http://hdl.handle.net/10316/96391.

Activities

Oral presentation

	Presentation title	Event name Host (Event location)
2024/02/09	Biomarcadores Retinianos no OCT	Colóquios de Oftalmologia 2024 Hospital de Santa Maria (Lisboa, Portugal)
2023/06/02	Multimodal Imaging for detection of DR lesions	EASDEC meeting 2024 EASDEC and AIBILI (Coimbra)
2023/06	Swept-source OCTA discriminates severity staging of NPDR: The CHART Study	EASDEC Meeting 2023 EASDEC and AIBILI (Coimbra, Portugal)
2023/03/24	Biomarkers in Diabetic Macular Edema	7ª Reunião GER Grupo de Estudos de Retina. Portugal
2022/11/10	A relação entre a PHDA e a Retina	Congresso Nacional de PHDA 2022 SPDA (Porto, Portugal)
2021/10/28	Ganglion Cell-Inner Plexiform layer alteration in the initial stages of diabetic retinopathy in type 2 diabetic patients: a 5-year longitudinal study	EASDec Congress 2021 EASDEC (Odense, Denmark)
2021/07/17	Microaneurysm Turnover in eyes with mild nonproliferative diabetic retinopathy is associated with progression and development of sight-threatening complications: a 5-year longitudinal study	Posterior Segment Day of Pan-American Research Day Pan-American Association of Ophthalmology (Virtual)
2020/11/05	Different Retinopathy Phenotypes in DR type 2 show different five -year risks for development of DME and PDR	EASDec Congress 2020 (Barcelona, Spain)
2019/12/07	Estudo CORDIS - Um ensaio longitudinal perspetivo e intervencional numa população de doentes diabéticos tipo 2 com retinopatia ligeira a moderada	62º Congresso Português de Oftalmologia (Vilamoura, Portugal)
2019/09/05	Five-year progression of diabetic retinopathy (PROGRESS Study) - DR Phenotypes as predictors of 5-year progression	19th EURETINA Congress (Paris, France)
2019/05/16	Multimodal imaging of the initial stages of diabetic retinopathy: different disease pathways in different patients	EASDec Congress 2019 (Amsterdam , Netherlands)
2018/10	Palestrante em Sessão Clínica: DMI e EMD - update	Sessão Clínica: DMI e EMD Bayer (Aveiro, Portugal)
2018/09/20	Characterization of the initial stages of diabetic retinal disease using OCT and OCTA	18th EURETINA Congress EURETINA - European Society of Retina Specialists (Viena, Austria)
2018/09	Palestrante na sessão: Eyecare retina - restabelece o equilíbrio na progressão da RD	Sessão: Eyecare retina Davi (Coimbra, Portugal)
2018/07	Palestrante em Sessão Clínica: VEGF - Clinical cases	Sessão Clínica: VEGF Novartis (Aveiro, Portugal)
2018/07	Palestrante no curso de formação interna da AIBILI: Doenças oftálmicas e Técnicas de Diagnóstico	Curso de formação interna da AIBILI: Doenças oftálmicas e Técnicas de Diagnóstico AIBILI (Coimbra, Portugal)
2018/05	Characterization of the initial stages of diabetic retinopathy using OCT and OCTA	EASDEC 2018 EASDEC - European Association for the Study of Diabetes Eye Complications (Belfast, United Kingdom)
2016/12/08	Uso de anti-VEGF no tratamento das oclusões venosas em Portugal - resultados da prática clínica	59º Congresso Português de Oftalmologia (Coimbra, Portugal)
2016/12/08	Comparison of diabetic retinopathy classification using fluorescein angiography and optical coherence tomography angiography	59º Congresso Português de Oftalmologia (Coimbra, Portugal)
2016/12	Uso de ANTI-VEGF no tratamento das oclusões venosas em Portugal - Resultados da prática clínica	59º Congresso Português de Oftalmologia Sociedade Portuguesa de Oftalmologia (Coimbra, Portugal)
2016/09/08	Comparison of diabetic retinopathy classification using fluorescein angiography and optical coherence tomography angiography	16th EURETINA Congress (Copenhaga, Denmark)
2016/06/04	Palestrante em VIOLET STUDY Investigator Meeting - Central Reading Center Procedures	VIOLET STUDY Investigator Meeting (viena, Austria)
2016/06	Methods for Quantification of Retinal Microvascular Density in Cirrus AngioPlex OCT Angiography (OCTA) Images	EASDEC 2016 EASDEC - European Association for the Study of Diabetes Eye Complications (Manchester, United Kingdom)
2015/02/07	Novas Perspectivas em tomografia de coerência óptica do segmento posterior - Apresentação de casos clínicos	Sessões Clínicas do Hospital da Luz (Lisboa, Portugal)
2014/10	Neuroprotecção em Glaucoma	Davi (Coimbra, Portugal)
2013/01	Palestrante no Curso de Formação Básica em Oftalmologia: DMI e Angiogénese- Anatomia e Fisiologia Ocular. Ensaios Clínicos com anti-VEGF	Curso de Formação Básica em Oftalmologia AIBILI (Coimbra, Portugal)
2011/12	Moxifloxacina intracamerular (0,5% vs 0,25%) vs Cefuroxima intracamerular profiláctica na cirurgia de catarata- Estudo comparativo	54º Congresso Português de Oftalmologia Sociedade Portuguesa de Oftalmologia (Vilamoura, Portugal)
2011/12	Terapia combinada com ranibizumab e terapia fotodinâmica no tratamento da Vasculopatia Polipoidal Idiopática- resultados visuais e anatómicos	54º Congresso Português de Oftalmologia Sociedade Portuguesa de Oftalmologia (Vilamoura, Portugal)
2011/09	Prophylactic intracameral moxifloxacin (0.5% vs 0.25%) and cefuroxime in modern cataract surgery	XXIX Congress of the ESCRS ESCRS - European Society of Cataract and Refractive Surgeons (Viena)
2011/06	Intravitreal injection of Ranibizumab for AMD: 3 years experience. What determines the outcome?	Joint Congresso of SOE AAO SOE - Sociedade Espanhola de Oftalmologia (SOE) (Genebra, Switzerland)
2011/04	Autosomal Dominant Optic Atrophy- Clinical and molecular characterization of ten Portuguese families	XVIII Curso Panamericano de la Asociación Panamericana de Oftalmología PAAO - Asociación Panamericana de Oftalmología (Estoril, Portugal)
2010/09	Intravitreal injection of Ranibizumab for AMD: 3 years experience. What determines the outcome?	10th EURETINA 2010 EURETINA - European Society of Retina Specialists (Paris, France)
2009/12	Correcção cirúrgica de malposição palpebral senil- Resultados de uma técnica	52º Congresso Português de Oftalmologia Sociedade Portuguesa de Oftalmologia (Vilamoura, Portugal)
2009/12	O Ranibizumab no tratamento das membranas ocultas, minimamente clássicas e predominantemente clássicas da DMRI	52º Congresso Português de Oftalmologia Sociedade Portuguesa de Oftalmologia (Vilamoura, Portugal)
2009/07	Tumor da órbita e seios perinasais	Reunião Conjunta dos Grupos Portugueses de Inflamação Ocular, Oftalmologia Pediátrica e Estrabismo e Patologia, Oncologia e Genética Ocular (Funchal, Portugal)
2009/07	Pseudo-chalázio palpebral	Reunião Conjunta dos Grupos Portugueses de Inflamação Ocular, Oftalmologia Pediátrica e Estrabismo e Patologia, Oncologia e Genética Ocular (Funchal, Portugal)
2009/07	Retinite em HIV	Reunião Conjunta dos Grupos Portugueses de Inflamação Ocular, Oftalmologia Pediátrica e Estrabismo e Patologia, Oncologia e Genética Ocular (Funchal, Portugal)
2008/12	Microscopia Confocal no diagnóstico das infecções corneanas	51º Congresso Português de Oftalmologia Sociedade Portuguesa de Oftalmologia (Porto, Portugal)

Supervision

	Thesis Title Role	Degree Subject (Type) Institution / Organization
2018 - 2019	Characterization of Retinal Disease Progression in a 5-Year Longitudinal Study of Eyes with nonproliferative Retinopathy in Diabetes Type 2 Co-supervisor	Mestrado integrado em Medicina (Master) Universidade de Coimbra, Portugal

Event organisation

	Event name Type of event (Role)	Institution / Organization
2023/06/01 - 2023/06/03	EASDEC 2023 conference organization, since the logistics to the scientific program. (2023/06/01 - 2023/06/03) Congress (President of the Organising Committee)	Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal

Event participation

	Activity description Type of event	Event name Institution / Organization
2023/08/27 - 2023/08/28	Participação na reunião do Grupo Português de Retina e Vítreo Congress	Reunião do Grupo Português de Retina e Vítreo
2023/04/21 - 2023/04/27	Poster presenter - Characterization of two-year progression of capillary closure in nonproliferative diabetic retinopathy Congress	ARVO Annual Meeting 2023 Arvo Foundation for Eye Research, United States
2021/07/17 - 2021/07/17	Posterior Segment Day of Pan-American Research Day - Apresentação de comunicação oral Congress	Posterior Segment Day of Pan-American Research Day Pan-American Association of Ophthalmology, United States
2021/05/01 - 2021/05/07	ARVO Annual Meeting 2021-Apresentação de poster Congress	ARVO Annual Meeting 2021 Arvo Foundation for Eye Research, United States
2020/12/10 - 2020/12/12	63° Congresso Português de Oftalmologia Congress	63° Congresso Português de Oftalmologia Sociedade Portuguesa de Oftalmologia, Portugal
2020/11/05 - 2020/11/07	EASDec 2020 30th Annual Virtual Meeting Congress	EASDec 2020 30th Annual Virtual Meeting EASDec-European Association for the Study of Diabetes Eye Complications Study Group, United Kingdom
2020/10/02 - 2020/10/04	EURETINA 2020 Virtual Congress	20th EURETINA Congress EURETINA - European Society of Retina Specialists, Ireland
2020/01/18 - 2020/01/19	Reunião do GER Meeting	Reunião do GER GER - Grupo de Estudos de Retina de Portugal, Portugal
2019/12/05 - 2019/12/07	62º Congresso da Sociedade Portuguesa de oftalmologia Congress	62º Congresso da Sociedade Portuguesa de oftalmologia Sociedade Portuguesa de Oftalmologia, Portugal
2019/09/05 - 2019/09/08	19th EURETINA 2019. Paris, France Congress	EURETINA 2019 EURETINA - European Society of Retina Specialists, Ireland
2018/12/05 - 2018/12/08	61º Congresso Português de Oftalmologia. Vilamoura, Portugal Congress	61º Congresso Português de Oftalmologia Sociedade Portuguesa de Oftalmologia, Portugal
2018/11/09 - 2018/11/10	II Reunião Conjunta do Grupo Português de Retina e Vítreo e da Sociedade Espanhola de Retina e Vítreo Congress	II Reunião Conjunta do Grupo Português de Retina e Vítreo e da Sociedade Espanhola de Retina e Vítreo Sociedade Portuguesa de Oftalmologia, Portugal
2018/09/20 - 2018/09/23	18th EURETINA Congress - Vienna, Austria Congress	18th EURETINA 2018 EURETINA - European Society of Retina Specialists, Ireland
2018/05/24 - 2018/05/26	28th EASDec Annual Meeting - Belfast, Northern Ireland Congress	EASDec 2018 EASDec-European Association for the Study of Diabetes Eye Complications Study Group, United Kingdom
2017/06/22 - 2017/06/22	4th Annual Coimbra Champalimaud Symposium Seminar	4th Annual Coimbra Champalimaud Symposium Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal
2017/03/25 - 2017/03/25	Reunião Científica Internacional do Grupo Estudos da Retina de Portugal. Lisboa, Portugal Congress	Reunião Científica Internacional do Grupo Estudos da Retina de Portugal Sociedade Portuguesa de Oftalmologia, Portugal
2016/12/08 - 2016/12/10	59º Congresso Português de Oftalmologia. Coimbra, Portugal Congress	59º Congresso Português de Oftalmologia Sociedade Portuguesa de Oftalmologia, Portugal
2016/09/08 - 2016/09/11	16th EURETINA Congress - Copenhagen, Denmark Congress	16th Congress - European Society of Retina Specialists EURETINA - European Society of Retina Specialists, Ireland
2016/06/22 - 2016/06/23	EUROPEAN CONSORTIUM FOR THE EARLY TREATMENT OF DIABETIC RETINOPATHY - 6th General Assembly. Manchester, United Kingdom Round table	6th General Assembly - EUROCONDOR
2016/06/17 - 2016/06/18	XXVI Jornadas de Oftalmologia. Coimbra, Portugal Congress	XXVI Jornadas de Oftalmologia Centro Hospitalar e Universitário de Coimbra EPE, Portugal
2016/05/23 - 2016/05/25	26th EASDec Annual Meeting - Manchester, United Kingdom Congress	EASDec 2016 EASDec-European Association for the Study of Diabetes Eye Complications Study Group, United Kingdom
2016/03/31 - 2016/04/02	7th World Congress on Controversies in Ophthalmology. Warsaw, Poland Congress	COPHy - World Congress on Controversies in Ophthalmology
2016/03/11 - 2016/03/12	Reunião do Grupo Português de Glaucoma e do Grupo Português de Inflamação Ocular. Viseu, Portugal Congress	Reunião do Grupo Português de Glaucoma e do Grupo Português de Inflamação Ocular Sociedade Portuguesa de Oftalmologia, Portugal
2015/12/03 - 2015/12/05	58º Congresso Português de Oftalmologia. Vilamoura, Portugal Congress	58º Congresso Português de Oftalmologia Sociedade Portuguesa de Oftalmologia, Portugal
2015/11/05 - 2015/11/08	European Retina Panel Programme. London, United Kingdom Congress	European Retina Panel Programme. EURETINA - European Society of Retina Specialists, Ireland
2015/05/03 - 2015/05/05	ARVO Annual Meeting 2015. Denver, EUA Congress	ARVO Annual Meeting 2015 The Association for Research in Vision and Ophthalmology Inc, United States
2014/05/04 - 2014/05/08	ARVO Annual Meeting 2014. Orlando, EUA Congress	ARVO Annual Meeting 2014 The Association for Research in Vision and Ophthalmology Inc, United States
2013/06/28 - 2013/06/29	International Symposium of Ophthalmology. Coimbra, Portugal Symposium	International Symposium of Ophthalmology Centro Hospitalar e Universitário de Coimbra EPE, Portugal
2013/06/27 - 2013/06/27	3rd Annual Coimbra Champalimaud Symposium with the institutions recognized as C-TRACER by the Champalimaud Foundation: LV Prasad Eye Institute in India, AIBILI in Coimbra and the Paulista Institute of Studies and Research in Ophthalmology from S. Paulo, Brazil. Symposium	3rd Annual Coimbra Champalimaud Symposium Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal
2013/05/05 - 2013/05/09	ARVO Annual Meeting 2013. Seattle, EUA Congress	ARVO Annual Meeting 2013 The Association for Research in Vision and Ophthalmology Inc, United States
2010/09/04 - 2010/09/08	Congress of European Society of Cataract and Refractive Surgeons. Paris, France Congress	XXVIII Congress of European Society of Cataract and Refractive Surgeons. European Society of Cataract and Refractive Surgeons, Ireland
2010/09/02 - 2010/09/05	10th Congress of the European Society of Retina Specialists. Paris, France Congress	10th Congress of the European Society of Retina Specialists. EURETINA - European Society of Retina Specialists, Ireland
2008/09/13 - 2008/09/17	Congress of the European Society of Cataract and Refractive Surgeons. Berlin, Germany Congress	XXVI Congress of the European Society of Cataract and Refractive Surgeons European Society of Cataract and Refractive Surgeons, Ireland

Course / Discipline taught

	Academic session	Degree Subject (Type)	Institution / Organization
2023/04/14 - Current	The Clinical Trial Process	(Curso de doutoramento (conclusão de unidades curriculares))	Faculdade Medicina UNiversidade Coimbra, Portugal
2023 - Current	Curso de Formação Avançada em Oftalmologia da SPO - Maculopatias Agudas		Sociedade Portuguesa de Oftalmologia, Portugal
2022/01 - Current	MEDICAL RETINA COURSE - Acute Maculopaties		GER - Grupo de Estudos de Retina de Portugal, Portugal
2023/03/13 - 2023/03/17	Multiple disease pathways in diabetic retinopathy	(Mestrado integrado)	Universidade de Coimbra Instituto de Investigação Clínica e Biomédica de Coimbra, Portugal
2022/02/22 - 2022/02/22	Abordagem prática em Medicina Geral e Familiar de aspetos relacionados com Oftalmologia: Consideração gerais; Abordagem diagnóstica e terapêutica de: olho vermelho, perda súbita de visão, diplopia, traumatismo ocular; Rastreio oftalmológico de grupos vulneráves: crianças, idosos, diabéticos		Formação Medicina Geral e Familiar, Portugal
2018/05 - 2018/06	Novas perspectivas em Angio-OCT	Novas perspectivas em Angio-OCT (3 sessões; 9h/cada)	Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
2009 - 2011	Assistente da cadeira de Oftalmologia	Medicina (Licenciatura)	Universidade de Coimbra Faculdade de Medicina, Portugal

Distinctions

Award

2016	Melhor Poster - Reunião GER 2016 GER - Grupo de Estudos de Retina de Portugal, Portugal
2011	2do. Premio al mejor trabajo - XVIII Curso Panamericano de la Asociación Panamericana de Oftalmología (PAAO) 2011 Pan-American Association of Ophthalmology, United States
2009	Prémio SPO/Novartis - Melhor Apresentação na Área da Retina do Congresso SPO 2009 Sociedade Portuguesa de Oftalmologia, Portugal
2008	Prémio Plácido 2008 – Melhor Trabalho no Congresso SPO 2008 Sociedade Portuguesa de Oftalmologia, Portugal