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Ruben Rafael Gonçalves Soares. Publicou 24 artigos em revistas especializadas. Atua na(s) área(s) de Ciências Médicas e da Saúde com ênfase em Biotecnologia Médica, Ciências Naturais com ênfase em Ciências Biológicas com ênfase em Biologia Molecular, Ciências Médicas e da Saúde com ênfase em Biotecnologia Médica com ênfase em Diagnóstico e Terapias de Base Genética, Ciências da Engenharia e Tecnologias com ênfase em Biotecnologia Industrial com ênfase em Tecnologias de BioProcessamento e Ciências da Engenharia e Tecnologias com ênfase em Biotecnologia Industrial com ênfase em Fermentação. No seu currículo Ciência Vitae os termos mais frequentes na contextualização da produção científica, tecnológica e artístico-cultural são: Biomolecule purification; Industrial bioprocesses; Multi-operation process; Scale-up; SWOT; .
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Identification

Personal identification

Full name
Ruben Rafael Gonçalves Soares

Citation names

  • Soares, Ruben R. G.

Author identifiers

Ciência ID
A817-2A3D-C10B
ORCID iD
0000-0001-5958-5232

Email addresses

  • ruben.soares@scilifelab.se (Professional)

Telephones

Mobile phone
  • (+46) 764506596 (Professional)

Addresses

  • Science For Life Laboratory, Tomtebodavägen 23A, 171 65 Solna, Sweden, 17165, Solna, Stockholm, Sweden (Professional)

Websites

Knowledge fields

  • Medical and Health Sciences - Medical Biotechnology
  • Natural sciences - Biological Sciences - Molecular Biology
  • Medical and Health Sciences - Medical Biotechnology - Gene-based Diagnostics and Therapeutic Interventions
  • Engineering and Technology - Industrial Biotechnology - Bioprocessing Technologies
  • Engineering and Technology - Industrial Biotechnology - Fermentation

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2)
Education
Degree Classification
2014/07 - 2018/10
Concluded
 Biotecnologia e Biociências (Doutoramento)
Major in Biosensores e Diagnóstico
Universidade de Lisboa Instituto Superior Técnico, Portugal
 Aprovado com Distinção e Louvor
2011/09 - 2013/11
Concluded
 Biotecnologia (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
 19 Valores
2008/09 - 2011/07
Concluded
 Bioquímica (Licenciatura)
Universidade de Lisboa Faculdade de Ciências, Portugal
 17 Valores
Affiliation

Science

Category
Host institution 		Employer
2020/05 - Current Postdoc (Research) Stockholms Universitet, Sweden
2018/11 - Current Postdoc (Research) Kungliga Tekniska Högskolan, Sweden
Projects

Grant

Designation Funders
2013/01 - 2015/12 Integrated Nanosystems for High Frequency and Neuroscience Applications
Provided by PTCRIS: 129032
129032
 Fundação para a Ciência e a Tecnologia, I.P.
Outputs

Publications

Conference paper
  1. Santos, D.R.; Soares, R.R.G.; Chu, V.; Aires-Barros, M.R.; Conde, J.P.. "A Multiplexed Integrated a-Si:H Photosensor for Simultaneous Detection of Mycotoxins for Point-of-use Food Safety Applications". 2016.
    10.1016/j.proeng.2016.11.403
  2. Soares, R.R.G.; Pinto, I.F.; Santos, D.R.; Azevedo, A.M.; Chu, V.; Aires-Barros, M.R.; Conde, J.P.. "A novel point-of-use, ultrafast and sensitive fluorescence immunoassay for the simultaneous detection of multiple mycotoxins using nanoporous agarose beads confined in microchannels". 2016.
  3. Pinto, I.F.; Santos, D.R.; Petrucci, G.; Soares, R.R.G.; Aires-Barros, M.R.; Chu, V.; Conde, J.P.; Azevedo, A.M.. "Development of a microfluidic device with integrated valves and photodiodes for rapid optimization of chromatographic separations of monoclonal antibodies". 2016.
  4. Pinto, I.F.; Santos, D.R.; Soares, R.R.G.; Aires-Barros, M.R.; Chu, V.; Azevedo, A.M.; Conde, J.P.. "Integration of Photosensors in a Nano-liter Scale Chromatography Column for the Online Monitoring of Adsorption/Desorption Kinetics of a Fluorophore-labeled Monoclonal Antibody". 2016.
    10.1016/j.proeng.2016.11.405
  5. Soares, R.R.G.; Santos, D.R.; Pinto, I.F.; Azevedo, A.M.; Chu, V.; Aires-Barros, M.R.; Conde, J.P.. "Point-of-use Ultrafast Single-step Detection of Food Contaminants: A Novel Microfluidic Fluorescence-based Immunoassay with Integrated Photodetection". 2016.
    10.1016/j.proeng.2016.11.208
  6. Tzouvadaki, I.; Madaboosi, N.; Soares, R.R.G.; Chu, V.; Conde, J.P.; De Micheli, G.; Carrara, S.. "'Bio-functionalization study of Memristive-Biosensors for early detection of prostate cancer'". 2015.
    10.1109/PRIME.2015.7251083
  7. Madaboosi, N.; Pedrosa, C.R.; Reis, M.F.; Soares, R.R.G.; Chu, V.; Conde, J.P.. "Microfluidic ELISA for sensing of prostate cancer biomarkers using integrated a-Si:H p-i-n photodiodes". 2014.
    10.1109/ICSENS.2014.6985141
  8. Soares, R.; Silva, D.F.C.; Azevedo, A.M.; Fernandes, P.; Chu, V.; Conde, J.P.; Aires-Barros, M.R.. "ATPS from natural products to large biomolecules". 2013.
Journal article
  1. Tharagan Kumar; Ruben R. G. Soares; Leyla Ali Dholey; Harisha Ramachandraiah; Negar Abbasi Aval; Zenib Aljadi; Torbjörn Pettersson; Aman Russom. "Multi-layer assembly of cellulose nanofibrils in a microfluidic device for the selective capture and release of viable tumor cells from whole blood". Nanoscale (2020): https://doi.org/10.1039/D0NR05375A.
    10.1039/D0NR05375A
  2. Inês F. Pinto; Ruben R. G. Soares; Maria R. Aires-Barros; Virginia Chu; João P. Conde; Ana M. Azevedo. "Optimizing the Performance of Chromatographic Separations Using Microfluidics: Multiplexed and Quantitative Screening of Ligands and Target Molecules". Biotechnology Journal (2019): 1800593-1800593. https://doi.org/10.1002/biot.201800593.
    10.1002/biot.201800593
  3. Denis R. Santos; Ruben R. G. Soares; Ines F. Pinto; Catarina R. F. Caneira; Rui M. R. Pinto; Virginia Chu; Joao Pedro Conde. "Label-Free Detection of Biomolecules in Microfluidic Systems Using On-Chip UV and Impedimetric Sensors". IEEE Sensors Journal 19 18 (2019): 7803-7812. https://doi.org/10.1109/JSEN.2019.2917305.
    10.1109/JSEN.2019.2917305
  4. Mariana N. São Pedro; Ana M. Azevedo; Maria R. Aires-Barros; Ruben R. G. Soares. "Minimizing the Influence of Fluorescent Tags on IgG Partition in PEG–Salt Aqueous Two-Phase Systems for Rapid Screening Applications". Biotechnology Journal 14 8 (2019): 1800640-1800640. https://doi.org/10.1002/biot.201800640.
    10.1002/biot.201800640
  5. Inês F Pinto; Denis R Santos; Catarina R F Caneira; Ruben R G Soares; Ana M Azevedo; Virginia Chu; João P Conde. "Optical biosensing in microfluidics using nanoporous microbeads and amorphous silicon thin-film photodiodes: quantitative analysis of molecular recognition and signal transduction". Journal of Micromechanics and Microengineering (2018): https://doi.org/10.1088/1361-6439/aac66c.
    10.1088/1361-6439/aac66c
  6. Roberta Epifania; Ruben R.G. Soares; Inês F. Pinto; Virginia Chu; João P. Conde. "Capillary-driven microfluidic device with integrated nanoporous microbeads for ultrarapid biosensing assays". Sensors and Actuators B: Chemical 265 (2018): 452-458. https://doi.org/10.1016/j.snb.2018.03.051.
    10.1016/j.snb.2018.03.051
  7. Ruben R. G. Soares; Denis R. Santos; Inês F. Pinto; Ana M. Azevedo; M. Raquel Aires-Barros; Virginia Chu; João P. Conde. "Multiplexed microfluidic fluorescence immunoassay with photodiode array signal acquisition for sub-minute and point-of-need detection of mycotoxins". Lab on a Chip (2018): https://doi.org/10.1039/C8LC00259B.
    10.1039/C8LC00259B
  8. Machado, J.M.D.; Soares, R.R.G.; Chu, V.; Conde, J.P.. "Multiplexed capillary microfluidic immunoassay with smartphone data acquisition for parallel mycotoxin detection". Biosensors and Bioelectronics 99 (2018): 40-46. http://www.scopus.com/inward/record.url?eid=2-s2.0-85024868873&partnerID=MN8TOARS.
    10.1016/j.bios.2017.07.032
  9. Pinto, I.F.; Santos, D.R.; Soares, R.R.G.; Aires-Barros, M.R.; Chu, V.; Azevedo, A.M.; Conde, J.P.. "A regenerable microfluidic device with integrated valves and thin-film photodiodes for rapid optimization of chromatography conditions". Sensors and Actuators, B: Chemical 255 (2018): 3636-3646. http://www.scopus.com/inward/record.url?eid=2-s2.0-85030467065&partnerID=MN8TOARS.
    10.1016/j.snb.2017.09.167
  10. Ruben R. G. Soares; Alessandra Ricelli; Corrado Fanelli; Domenico Caputo; Giampiero de Cesare; Virginia Chu; M. Raquel Aires-Barros; João P. Conde. "Advances, challenges and opportunities for point-of-need screening of mycotoxins in foods and feeds". The Analyst (2018): https://doi.org/10.1039/C7AN01762F.
    10.1039/C7AN01762F
  11. Soares, R.R.G.; Santos, D.R.; Chu, V.; Azevedo, A.M.; Aires-Barros, M.R.; Conde, J.P.. "A point-of-use microfluidic device with integrated photodetector array for immunoassay multiplexing: Detection of a panel of mycotoxins in multiple samples". Biosensors and Bioelectronics 87 (2017): 823-831. http://www.scopus.com/inward/record.url?eid=2-s2.0-84988037419&partnerID=MN8TOARS.
    10.1016/j.bios.2016.09.041
  12. Soares, R.R.G.; Azevedo, A.M.; Fernandes, P.; Chu, V.; Conde, J.P.; Aires-Barros, M.R.. "A simple method for point-of-need extraction, concentration and rapid multi-mycotoxin immunodetection in feeds using aqueous two-phase systems". Journal of Chromatography A 1511 (2017): 15-24. http://www.scopus.com/inward/record.url?eid=2-s2.0-85021980127&partnerID=MN8TOARS.
    10.1016/j.chroma.2017.07.004
  13. Bras, E.J.S.; Soares, R.R.G.; Azevedo, A.M.; Fernandes, P.; Arévalo-Rodríguez, M.; Chu, V.; Conde, J.P.; Aires-Barros, M.R.. "A multiplexed microfluidic toolbox for the rapid optimization of affinity-driven partition in aqueous two phase systems". Journal of Chromatography A 1515 (2017): 252-259. http://www.scopus.com/inward/record.url?eid=2-s2.0-85028061734&partnerID=MN8TOARS.
    10.1016/j.chroma.2017.07.094
  14. Santos, D.R.; Soares, R.R.G.; Chu, V.; Conde, J.P.. "Performance of Hydrogenated Amorphous Silicon Thin Film Photosensors at Ultra-Low Light Levels: Towards Attomole Sensitivities in Lab-on-Chip Biosensing Applications". IEEE Sensors Journal 17 21 (2017): 6895-6903. http://www.scopus.com/inward/record.url?eid=2-s2.0-85030246995&partnerID=MN8TOARS.
    10.1109/JSEN.2017.2751253
  15. Soares, R.R.G.; Silva, D.F.C.; Fernandes, P.; Azevedo, A.M.; Chu, V.; Conde, J.P.; Aires-Barros, M.R.. "Miniaturization of aqueous two-phase extraction for biological applications: From micro-tubes to microchannels". Biotechnology Journal 11 12 (2016): 1498-1512. http://www.scopus.com/inward/record.url?eid=2-s2.0-84987642617&partnerID=MN8TOARS.
    10.1002/biot.201600356
  16. Soares, R.R.G.; Ramadas, D.; Chu, V.; Aires-Barros, M.R.; Conde, J.P.; Viana, A.S.; Cascalheira, A.C.. "An ultrarapid and regenerable microfluidic immunoassay coupled with integrated photosensors for point-of-use detection of ochratoxin A". Sensors and Actuators, B: Chemical 235 (2016): 554-562. http://www.scopus.com/inward/record.url?eid=2-s2.0-84973354072&partnerID=MN8TOARS.
    10.1016/j.snb.2016.05.124
  17. Conde, J.P.; Madaboosi, N.; Soares, R.R.G.; Fernandes, J.T.S.; Novo, P.; Moulas, G.; Chu, V.. "Lab-on-chip systems for integrated bioanalyses". Essays in Biochemistry 60 1 (2016): 121-131. http://www.scopus.com/inward/record.url?eid=2-s2.0-85013477395&partnerID=MN8TOARS.
    10.1042/EBC20150013
  18. Pinto, I.F.; Caneira, C.R.F.; Soares, R.R.G.; Madaboosi, N.; Aires-Barros, M.R.; Conde, J.P.; Azevedo, A.M.; Chu, V.. "The application of microbeads to microfluidic systems for enhanced detection and purification of biomolecules". Methods (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-85007566334&partnerID=MN8TOARS.
    10.1016/j.ymeth.2016.12.005
  19. Jolly, P.; Damborsky, P.; Madaboosi, N.; Soares, R.R.G.; Chu, V.; Conde, J.P.; Katrlik, J.; Estrela, P.. "DNA aptamer-based sandwich microfluidic assays for dual quantification and multi-glycan profiling of cancer biomarkers". Biosensors and Bioelectronics 79 (2016): 313-319. http://www.scopus.com/inward/record.url?eid=2-s2.0-84951171198&partnerID=MN8TOARS.
    10.1016/j.bios.2015.12.058
  20. Pinto, I.F.; Soares, R.R.G.; Rosa, S.A.S.L.; Aires-Barros, M.R.; Chu, V.; Conde, J.P.; Azevedo, A.M.. "High-Throughput Nanoliter-Scale Analysis and Optimization of Multimodal Chromatography for the Capture of Monoclonal Antibodies". Analytical Chemistry 88 16 (2016): 7959-7967. http://www.scopus.com/inward/record.url?eid=2-s2.0-84983086201&partnerID=MN8TOARS.
    10.1021/acs.analchem.6b00781
  21. Jacinto, M.J.; Soares, R.R.G.; Azevedo, A.M.; Chu, V.; Tover, A.; Conde, J.P.; Aires-Barros, M.R.. "Optimization and miniaturization of aqueous two phase systems for the purification of recombinant human immunodeficiency virus-like particles from a CHO cell supernatant". Separation and Purification Technology 154 (2015): 27-35. http://www.scopus.com/inward/record.url?eid=2-s2.0-84942246622&partnerID=MN8TOARS.
    10.1016/j.seppur.2015.09.006
  22. Soares, Ruben. "Partitioning in aqueous two-phase systems: Analysis of strengths, weaknesses, opportunities and threats". Biotechnology Journal 10 8 (2015): 1158-1169. http://dx.doi.org/10.1002/biot.201400532.
    10.1002/biot.201400532
  23. Madaboosi, N.; Soares, R.R.G.; Chu, V.; Conde, J.P.. "A microfluidic immunoassay platform for the detection of free prostate specific antigen: A systematic and quantitative approach". Analyst 140 13 (2015): 4423-4433. http://www.scopus.com/inward/record.url?eid=2-s2.0-84931050325&partnerID=MN8TOARS.
    10.1039/c5an00364d
  24. Soares, R.R.G.; Novo, P.; Azevedo, A.M.; Fernandes, P.; Aires-Barros, M.R.; Chu, V.; Conde, J.P.. "On-chip sample preparation and analyte quantification using a microfluidic aqueous two-phase extraction coupled with an immunoassay". Lab on a Chip - Miniaturisation for Chemistry and Biology 14 21 (2014): 4284-4294. http://www.scopus.com/inward/record.url?eid=2-s2.0-84907611826&partnerID=MN8TOARS.
    10.1039/c4lc00695j
  25. Soares, R.R.G.; Novo, P.; Azevedo, A.M.; Fernandes, P.; Chu, V.; Conde, J.P.; Aires-Barros, M.R.. "Aqueous two-phase systems for enhancing immunoassay sensitivity: Simultaneous concentration of mycotoxins and neutralization of matrix interference". Journal of Chromatography A 1361 (2014): 67-76. http://www.scopus.com/inward/record.url?eid=2-s2.0-84919691408&partnerID=MN8TOARS.
    10.1016/j.chroma.2014.08.007

Other

Other output
  1. Point-of-care detection of SARS-CoV-2 in nasopharyngeal swab samples using an integrated smartphone-based centrifugal microfluidic platform. 2020. Ruben R. G. Soares; Ahmad S. Akhtar; Inês F. Pinto; Noa Lapins; Donal Barrett; Gustaf Sandh; Xiushan Yin; Vicent Pelechano; Aman Russom. https://doi.org/10.1101/2020.11.04.20225888.
    10.1101/2020.11.04.20225888