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Ana Cristina Gonçalves, Ph.D., is an Assistant Professor at the Faculty of Medicine, University of Coimbra. She received her Microbial Biology and Genetic degree (BSc) in 2004 at the Faculty of Sciences of the University of Lisbon (FCUL). Then, at FMUC, she obtained a Clinical Nutrition Master's degree (MSc) in 2009 and a Ph.D. in Health Sciences in 2016. She is a researcher at Coimbra Institute for Clinical and Biomedical Research (iCBR) - Group of Environment Genetics and Oncobiology (CIMAGO) of FMUC and Centre for Innovative Biomedicine and Biotechnology Consortium (CIBB). She is a member of several societies, namely the European Association for Cancer Research (EACR), Portuguese Association for Cancer Research (ASPIC), and Portuguese Hematology Society (SPH), and a member of various COST Actions. Ana Cristina is a member of the Editorial Board/Advisory Review Board of Translational Oncology, Cancer Treatment and Research Communications, International Journal of Molecular Sciences (Molecular Oncology section), and Experimental and Therapeutic Medicine. Ana Cristina regularly serves as a reviewer in several Q1 journals. She teaches Molecular and Cellular Biology, Nutritional Biology, Scientific Writing and Communication, and Applied Molecular Biology at FMUC. She has supervised 27 Master Thesis (2 ongoing) and 4 Ph.D. (ongoing) and participated in more than 27 Investigation Projects. Currently, Ana Cristina Gonçalves' research is focusing on: molecular and cellular mechanisms involved in cancer; new biomarkers in susceptibility, diagnosis, prognosis, and therapy response; DNA damage in cancer; and circadian rhythms in cancer. She has published more than 95 full articles (PubMed list of articles: https://www.ncbi.nlm.nih.gov/myncbi/18c-ANcfLW55i/bibliography/public/; H-index=23, i10-index=57, citations=1806; Scopus 02/2024), >285 abstracts in international and national journals with peer review, 7 Book Chapters, and received 40 prizes and awards. Ana Cristina frequently engages in outreach activities, namely the European Researchers Night and other activities targeted at the general society.
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Identification

Personal identification

Full name
Ana Cristina Pereira Gonçalves

Citation names

  • Gonçalves AC

Author identifiers

Ciência ID
A81E-49AB-AC47
ORCID iD
0000-0003-1470-4802
Researcher Id
V-2202-2017
Scopus Author Id
36096765300

Knowledge fields

  • Natural sciences - Biological Sciences - Biology
  • Medical and Health Sciences - Basic Medicine
  • Medical and Health Sciences - Basic Medicine - Human Genetics
  • Medical and Health Sciences - Health Sciences - Nutrition, Dietetics

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
English Upper intermediate (B2) Advanced (C1) Advanced (C1) Advanced (C1)
Spanish; Castilian Intermediate (B1) Intermediate (B1) Intermediate (B1) Advanced (C1)
Affiliation

Science

Category
Host institution 		Employer
2019 - Current Researcher (Research) Universidade de Coimbra Center for Innovative Biomedicine and Biotechnology (CIBB), Portugal
2018 - Current Researcher (Research) Universidade de Coimbra, Coimbra Institute for Clinical and Biomedical Research (iCBR), Portugal
2012/01 - 2018/02/28 Researcher (Research) Universidade de Coimbra Faculdade de Medicina, Portugal
2005 - 2018 Researcher (Research) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2005 - 2018 Researcher (Research) Universidade de Coimbra, Centro de Investigação em Meio Ambiente, Genética e Oncobiologia, Portugal

Teaching in Higher Education

Category
Host institution 		Employer
2018/03 - Current Assistant Professor (University Teacher) Universidade de Coimbra Faculdade de Medicina, Portugal
2009/01 - 2009/12 Invited Assistant (University Teacher) Universidade de Coimbra Faculdade de Medicina, Portugal
2005/01 - 2009/01 Lecturer (University Teacher) Universidade de Coimbra Faculdade de Medicina, Portugal

Other Careers

Category
Host institution 		Employer
2009/12 - 2012/12 Técnico Superior (Técnico Superior) Universidade de Coimbra Faculdade de Medicina, Portugal
Projects

Grant

Designation Funders
2023 - Current Relevância clínica das plaquetas como biomarcadores não invasivos no Mieloma Múltiplo - Um estudo piloto
APCL 2023
Researcher
Associação Portuguesa Contra a Leucemia, Portugal

Sociedade Portuguesa de Hematologia, Portugal

Amgen Biofarmaceutica Lda, Portugal
Ongoing
2021/02 - Current Clinical implications of DNA damage repair in acute myeloid leukemia
NRC-LPCC/CIMAGO 2020
Principal investigator
Liga Portuguesa Contra o Cancro Núcleo Regional do Centro, Portugal
Ongoing
2021/02 - Current Clinical relevance of platelets as non-invasive biomarkers in diffuse large B-cell lymphoma – A pilot study
NRC-LPCC/CIMAGO 2020
Researcher
Liga Portuguesa Contra o Cancro Núcleo Regional do Centro, Portugal
Ongoing
2019/01 - 2019/12 EPO-EPOR axis in MDS - Clinical relevance as prognostic and drug response biomarker
LPCC-NRC/CIMAGO 2019
Principal investigator
Liga Portuguesa Contra o Cancro Núcleo Regional do Centro, Portugal
Concluded
2018 - 2019 Identification of new response markers to Bortezomib and Lenalidomide treatment in patients with multiple myeloma – The role of NF-kB and NRF2/KEAP1
04/18
Researcher
Liga Portuguesa Contra o Cancro Núcleo Regional do Centro, Portugal

Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia, Portugal
Concluded
2018 - 2019 Molecular Characterization and Clinical Relevance of the crosstalk between the NRF2/KEAP1 axis and Erythropoietin in Hematopoietic Stem Cell - Clinical Relevance in Myelodysplastic Syndromes.
02/19
Researcher
Liga Portuguesa Contra o Cancro Núcleo Regional do Centro, Portugal

Sociedade Portuguesa de Hematologia, Portugal
Concluded
2018 - 2019 The NRF2-KEAP1 axis as a potential prognostic biomarker and therapeutic target in chronic lymphocytic leukemia
03/18
Researcher
Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia, Portugal

Sociedade Portuguesa de Hematologia, Portugal
Concluded
2016/01 - 2018/12 Crosstalk between perivascular adipose tissue and blood vessels in obesity and vascular dysfunction
grant.Provided by PTCRIS: 143079
 Stichting Weten

Contract

Designation Funders
2021/01/01 - 2025/12/31 Center for Innovative Biomedicine and Biotechnology - Associate Laboratory
LA/P/0058/2020
10.54499/LA/P/0058/2020
Universidade de Coimbra, Portugal

Universidade Nova de Lisboa ¿Laboratório de Instrumentação Engenharia Biomédica e Física da Radiação, Portugal

Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2023/03/06 - 2024/09/05 Early biomarkers to stop vascular dysfunction associated with obesity and type 2 diabetes
2022.04526.PTDC
10.54499/2022.04526.PTDC
Universidade de Coimbra, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2020 - 2023 CôaMedPlants-Preservation of natural and cultural heritage and scientific validation of practices with medicinal plants from Côa Valley
COA/BRB/0019/2019
Researcher
Fundação para a Ciência e a Tecnologia, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2019 - 2021 Red Transfronteriza de Innovación en Diagnóstico Precoz de Leucemia para un envejecimiento saludable IDIAL-NET
POCTEP 2308
Researcher
Ongoing
2019/01/01 - 2019/12/31 CNC. IBILI
UID/NEU/04539/2019
Universidade de Coimbra, Portugal

Universidade Nova de Lisboa ¿Laboratório de Instrumentação Engenharia Biomédica e Física da Radiação, Portugal

Universidade de Coimbra Instituto de Ciências Nucleares Aplicadas à Saúde, Portugal

Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2016/07/01 - 2019/12/31 Crosstalk between perivascular adipose tissue and blood vessels in obesity and vascular dysfunction
PTDC/BIM-MET/4447/2014
Universidade de Coimbra, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2016 - 2019 The Role of Exercise Training in the Treatment of Resistant Hypertension
PTDC/DTP-DES/1725/2014
Researcher
Fundação para a Ciência e a Tecnologia, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2012/04/01 - 2015/09/30 Pathways of adipose tissue dysfunction: a route for obesity- related cancer
PTDC/SAU-MET/121133/2010
Universidade de Coimbra, Portugal

Centro Hospitalar e Universitário de Coimbra EPE, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2011/04/04 - 2014/10/02 Synthesis and Pre-clinical Evaluation of Novel Estradiol-Based Indium Complexes for Targeted Radiotherapy of Tumors
PTDC/QUI-QUI/111891/2009
Universidade de Lisboa Instituto Superior Técnico, Portugal

Universidade de Coimbra, Portugal
Fundação para a Ciência e a Tecnologia
Concluded

Other

Designation Funders
2023 - Current Circular RNAs in hematological neoplasms: Potential biomarker from diagnosis to therapy
NRC-LPCC/CIMAGO 2023
Researcher
Liga Portuguesa Contra o Cancro Núcleo Regional do Centro, Portugal
Ongoing
2023 - Current Clinical Relevance of non-invasive biomarkers in bone and soft tissue tumors
NRC-LPCC/CIMAGO 2023
Principal investigator
Liga Portuguesa Contra o Cancro Núcleo Regional do Centro, Portugal
Ongoing
2022/11 - Current Clinical implications of DNA damage repair in acute myeloid leucemia
SPH02/22
Principal investigator
Sociedade Portuguesa de Hematologia, Portugal
Ongoing
2022/01 - Current Synthetic lethality in acute myeloid leukemia – Role of DNA damage response
CIMAGO 04/22
Principal investigator
Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia, Portugal
Ongoing
2022/01 - Current Evaluation of molecular mechanisms of resistance to proteasome inhibitors and immunomodulatory drugs in multiple myeloma
CIMAGO 05/22
Researcher
Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia, Portugal
Ongoing
2022/01 - Current The role of platelets in diagnosis, prognosis and therapeutic monitoring in diffuse large B-cell lymphoma
CIMAGO 06/22
Researcher
Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia, Portugal
Ongoing
2022/01 - Current HemaCirc: CircRNAs as an innovative tool in hematological neoplasms
CIMAGO 08/22
Researcher
Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia, Portugal
Ongoing
2016 - Current Epigenetic in chronic lymphocytic leukemia B - Impact in prognosis and therapy
FMUC-BST-2016-220
Researcher
Universidade de Coimbra Faculdade de Medicina, Portugal

Banco Santander Totta, Portugal
Concluded
2014 - Current The role of microRNAs for chronic myeloid leukemia therapeutic selection
FMUC-BST-2016-214
10/14
Researcher
Universidade de Coimbra Faculdade de Medicina, Portugal

Banco Santander Totta, Portugal

Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia, Portugal
Concluded
2012 - Current Modulação redox em neoplasias hematológicas – O NRF2 com novo marcador e alvo terapêutico
10/12
Researcher
Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia, Portugal
Concluded
2012 - Current Characterization of Cellular and Molecular mechanisms involved in Sensitivity and Resistance to BCR-ABL targeted therapies in Chronic Myelogenous Leukemia
18/12
Researcher
Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia, Portugal
Concluded
2018 - 2022 New diagnostic and therapeutic tools against multidrug resistant tumors - COST action
CA17104
Researcher
Ongoing
2009 - 2016 Caracterização Clínica e Molecular da Síndrome Mielodisplásica – Implicações no Prognóstico e Terapêutica
24/09
Researcher
Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia, Portugal
Concluded
2009 - 2016 Avaliação da relação entre o stress oxidativo e modulação epigenética em neoplasias hematológicas - Papel da variabilidade genética/epigenética no risco de desenvolver neoplasias hematológicas e/ou resistência ao tratamento
22/09
Researcher
Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia, Portugal
Concluded
2009 - 2015 Alterações Celulares e Moleculares no Mieloma Múltiplo – Implicações Clínicas e Terapêuticas
23/09
Researcher
Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia, Portugal
Concluded
2009 - 2014 Importância Clínica de Novos Marcadores Moleculares e Celulares no Cancro Colorectal
25/09
Researcher
Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia, Portugal
Concluded
2012 - 2013 The cross-talk between oxidative stress and epigenetics – A possible route in myeloid leukemia
GAI/2012
Researcher
Universidade de Coimbra Faculdade de Medicina, Portugal
Concluded
2008 - 2010 Apo2L/TRAIL as new therapeutic approach in cancer
02/08
Researcher
Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia, Portugal
Concluded
2007 - 2009 Nutrição e alterações epigenéticas na síndrome mielodisplásica – implicações prognósticas e terapêuticas
07/07
Researcher
Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia, Portugal
Concluded
2006 - 2008 Development of a cellular system for the study of Cr(VI)-induced lung carcinogenesis
16/06
Researcher
Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia, Portugal
Concluded
2006 - 2008 Estudo do efeito da clampagem per-operatória (manobra de Pringle) na função hepatocelular no modelo animal com fígado normal e com hepatocarcinoma
05/06
Researcher
Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia, Portugal
Concluded
2005 - 2007 Protein Kinase inhibitors – Molecular and cellular mechanisms of drug resistance to Enzastaurin
LILLY 2005
Researcher
Lilly Portugal Produtos Farmacêuticos Lda, Portugal
Concluded
2005 - 2006 Evaluation of Ubiquitin/Proteasome system in patients with Chronic Lymphocytic Leukaemias – Bortezomib as a potential therapeutic approach
JC-2005
Researcher
Janssen-Cilag Farmacêutica Lda, Portugal
Concluded
Outputs

Publications

Book chapter
  1. Bergantim, Rui; Jorge, Joana; Peixoto da Silva, Sara; Alves, Raquel; Gonçalves AC; Sarmento-Ribeiro, Ana Bela; Guimarães, José E.; Vasconcelos, M. Helena. "The Role of MicroRNAs in Mature B-Cell Neoplasias Drug Resistance". In Reference Module in Biomedical Sciences. Elsevier, 2024.
    10.1016/b978-0-443-15717-2.00013-5
  2. Sarmento Ribeiro, Ana Bela; Botelho, Maria Filomena; Gonçalves, Ana Cristina; Melo, Joana Barbosa; Laranjo, Mafalda; Alves, Raquel; Jorge, Joana; et al. "Aging-related neoplasia". In Aging, 547-575. Elsevier, 2023.
    10.1016/b978-0-12-823761-8.00026-4
  3. Sarmento-Ribeiro, AB; Gonçalves AC; Afonso, C.; Alves, R.; Góis, I.; Jorge, J.; Casalta, JE; et al. "Kinase Inhibitors in Cancer Therapy". In An Introduction to cancer therapy. Nova Science Publishers, 2020.
    Published
  4. Sarmento-Ribeiro, AB; Marques, B.; Afonso, C.; Gonçalves AC; Silva, N.; Simões, AT; Coucelo, M.; et al. "An updated approach to myelodysplastic syndromes". In Myelodysplastic Syndromes: From Diagnosis to Treatment Publisher. Nova Science Publishers, 2020.
    Published
  5. Mendes, F.; Domingues, C.; Schugk, S; Abrantes, AM; Gonçalves AC; Sales, T.; Teixo, R.; et al. "Irradiação da linha celular de linfoma difuso de grandes células B em dose única efeitos celulares e moleculares". In Ciências Aplicadas: Coletânea de Estudos. Portugal: CINEP/IPC, 2017.
    Published
  6. Sarmento-Ribeiro, AB; Gonçalves, A.C.; Ribeiro, AB; Cortesão, E.; Nascimento-Costa, JM. "From risk factors to prognosis in myelodysplasic syndromes: The role of genetic variance". In Myelodysplastic syndromes (MDS): Risk factors, treatment and prognosis. Nova Science Publishers, 2016.
    Published
  7. Sarmento-Ribeiro, AB; Lopes Ribeiro, A; Goncalves, AC; Carda, JP. "Molecular and Cellular characterization of chronic lymphocytic leukemia - Prognostic implications". In Horizons in cancer research., 141-164. Hauppauge NY (US): Nova Science Publishers, 2013.
    Published
Conference abstract
  1. Magalhães, M; Domínguez-Martín, EM; Jorge, J; Gonçalves AC; Duarte, AI; Oliveira, PJ; Efferth, T; Rijo, P; Cabral, C. "Unraveling the chemotherapeutic potential of Royleanone, a natural drug lead, against glioblastoma". Paper presented in EACR congress 2023, 2023.
    Published
  2. Serambeque, B; Carvalho, MJ; Correia-Barros, G; Pereira, N AM; Gonçalves AC; Pineiro, M; Botelho, MF; Pinho e Melo, TMVD; Laranjo, M. "Exploring ring-fused chlorins based photodynamic therapy as a conservative approach for endometrial cancer". Paper presented in EACR congress 2023, 2023.
    Published
  3. Alves, Raquel; Silva, Inês; Costa, Maria Inês; Lapa, B; Jorge, Joana; Gonçalves AC; Sarmento-Ribeiro, AB. "Buparlisib a promising therapeutic approach in chronic myeloid leukemia resistant to imatinib". Paper presented in EHA 2023 Hybrid Congress, 2023.
    Published
  4. Jorge, J; Constantino, B; Santiago, H; Costa, MI; Lapa, B; Alves, R; Gonçalves AC; Sarmento-Ribeiro AB. "NRF2 inhibition in combination with ibrutinib in the treatment of chronic lymphocytic leukemia– An in vitro study.". Paper presented in EHA 2023 Hybrid Congress, 2023.
    Published
  5. Alves, R; Almeida, AS; Costa, MI; Lapa, B; Jorge, J; Gonçalves AC; Geraldes, C; Sarmento-Ribeiro, AB. "Molecular mechanisms of resistance to immunomodulators in multiple myeloma: An in vitro study". Paper presented in EHA 2023 Hybrid Congress, 2023.
    Published
  6. Lapa, B; Costa, MI; Figueiredo, D; Jorge, J; Alves, R; Monteiro, AR; Silva, MR; et al. "The therapeutic potential of AZD-7648, a DNA-PK inhibitor, on acute myeloblastic leukemia". Paper presented in EACR congress 2023, 2023.
    Published
  7. Lapa, B; Portelinha, AP; Costa, MI; Jorge, J; Alves, R; Sarmento-Ribeiro, AB; Gonçalves AC. "Niraparib in B-cell lymphoid malignancies: Exploring synthetic lethality as target for therapy.". Paper presented in EHA 2023 Hybrid Congress, 2023.
    Published
  8. Lapa, B; Costa, MI; Jorge, J; Alves, R; Sarmento-Ribeiro, AB; Gonçalves AC. "Inhibition of the DNA damage response: A possible new route in acute myeloblastic leukemia treatment.". Paper presented in EHA 2023 Hybrid Congress, 2023.
    Published
  9. Jorge, J; Santiago, H; Constantino, B; Costa, MI; Lapa, B; Alves, R; Gonçalves AC; Sarmento-Ribeiro, AB. "Telaglenastat (CB-839) in monotherapy and in combination with epigenetic modulators or ibrutinib induces cell death in chronic lymphocytic leukemia cells". Paper presented in EHA 2023 Hybrid Congress, 2023.
    Published
  10. Magalhães, M; Domínguez-Martín, E; Jorge, J; Gonçalves AC; Oliveira, P; Efferth, T; Rijo, P; Cabral, C. "Unravelling an abietane diterpenoid with very promising chemotherapeutic potential against glioblastoma cells.". Paper presented in 71st International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research, 2023.
    Published
  11. Pais, A; Laranjo, M; Reis, C; Reis, S; Sousa, A; Silva, F; Jorge, J; et al. "Angiogenesis stimulation of cryopreserved ovarian tissue.". Paper presented in 27th European Congress of Obstetrics and Gynaecology, 2022.
  12. Magalhães, M; Domínguez- Martín, EM; Jorge, J; Gonçalves AC; Díaz-Lanza, AM; Manadas, B; Efferth, T; Rijo, P; Cabral, C. "Parvifloron D-based therapy for glioblastoma: targeting tumor microenvironment with a natural drug lead". Paper presented in 56th ESCI Annual Scientific Meeting, 2022.
    Published
  13. Lapa, Beatriz; Costa, Maria Inês; Jorge, Joana; Alves, Raquel; Gonçalves AC; Sarmento-Ribeiro, AB. "Therapeutic potential of DNA damage response in acute myeloblastic leukemia". Paper presented in EHA2022 Hybrid Congress, 2022.
    Published
  14. Jorge, Joana; Gaspar, T; Costa, MI; Lapa, B; Alves, R; Gonçalves AC; Sarmento-Ribeiro, AB. "Demethylating agents and histone deacetylase inhibitors as new therapeutic strategies in chronic lymphocytic leukemia". Paper presented in EHA2022 Hybrid Congress, 2022.
    Published
  15. Costa, MI; Lapa, B; Jorge, J; Alves, R; Sarmento-Ribeiro, AB; Gonçalves AC. "Zinc in the modulation of the antiproliferative and cytotoxic effects of Olaparib in acute myeloid leukemia". Paper presented in EHA2022 Hybrid Congress, 2022.
    Published
  16. Carda, JP; Gomes, R; Jorge, J; Gonçalves AC; Marques, B; Alves, R; Sarmento-Ribeiro, AB. "NRF2 modulators in chronic lymphocytic leukemia patients: a possible new therapeutic approach". Paper presented in EHA2022 Hybrid Congress, 2022.
    Published
  17. Afonso, C.; Roque, D.; Alves, R.; Magalhães, M.; Costa, MI; Gomes, E.; Figueiredo, D.; et al. "Unravelling resistance mechanisms to proteasome inhibitors in Multiple Myeloma". Paper presented in EHA2021 Virtual Congress, 2021.
    Published
  18. Costa, I.; Magalhães, N.; Roque, D.; Gomes, E.; Alves, R.; Jorge, J.; Lapa, B.; et al. "Zinc in the modulation of the DNA damage response – Preventive, genotoxic and cytotoxic roles in acute myeloid leukemia". Paper presented in EHA2021 Virtual Congress, 2021.
    Published
  19. Gomes, E.; Jorge, J.; Carda, JP; Costa, MI; Magalhães, N.; Roque, D.; Alves, R.; et al. "Relevance of NRF2/KEAP1 axis in chronic lymphocytic leukemia development.". Paper presented in EHA2021 Virtual Congress, 2021.
    Published
  20. Magalhães, N.; Figueiredo, D.; Alves, R.; Roque, D.; Costa, MI; Gomes, E.; Jorge, J.; et al. "NRF2 as a therapeutic target in acute leucemia – In vitro studies with oltipraz". Paper presented in EHA2021 Virtual Congress, 2021.
    Published
  21. Jorge, J.; Estevam, A.; Alves, R.; Lapa, B.; Nascimento-Costa, JM; Gonçalves AC; Sarmento-Ribeiro, AB. "Therapeutic potential of pimozide in acute lymphoblastic leukemia cell lines". Paper presented in 25th Congress of the European Hematology Association, 2020.
    Published
  22. Figueiredo, D.; Jorge, J.; Alves, R.; Lapa, B.; Gonçalves AC; Sarmento-Ribeiro, AB. "Can NRF2 modulation be a novel therapeutic approach in acute myeloblastic leukemia?". Paper presented in 25th Congress of the European Hematology Association, 2020.
    Published
  23. Gonçalves AC; Silva, D.; Marques, B.; Jorge, J.; Alves, R.; Ribeiro, AB; Cortesão, E.; Nascimento-Costa, JM; Sarmento-Ribeiro, AB. "Aldehyde dehydrogenase genetic variants influence the risk myelodysplastic syndromes and acute myeloid leukemia development and progression". Paper presented in 25th Congress of the European Hematology Association, 2020.
    Published
  24. Alves, R.; Gonçalves AC; Carda, JP; Jorge, J.; Duarte, S.; Pereira, A.; Ribeiro, IP; Carreira, IM; Sarmento-Ribeiro, AB. "Role of epigenetics in chronic lymphocytic leukemia pathogenesis and treatment". Paper presented in 25th Congress of the European Hematology Association, 2020.
    Published
  25. Alves, R.; Gonçalves AC; Jorge, J.; Afonso, C.; Roque, A.; Paiva, A.; Ribeiro, L.; Geraldes, C.; Sarmento-Ribeiro, AB. "Relevance of NF-kB and NRF2 transcription factors into multiple myeloma pathophysiology – A preliminary study". Paper presented in CIMAGO Meeting – Challenges in Oncobiology, 2020.
    Published
  26. Jorge, J.; Estevam, A.; Alves, R.; Lapa, B.; Nascimento-Costa, JM; Gonçalves AC; Sarmento-Ribeiro, AB. "STAT5 - A new therapeutic target in acute lymphoblastic leukemia?". Paper presented in CIMAGO Meeting – Challenges in Oncobiology, 2020.
    Published
  27. Silva, D.; Gonçalves AC; Marques, B.; Jorge, J.; Alves, R.; Ribeiro, AB; Cortesão, E.; Nascimento-Costa, JM; Sarmento-Ribeiro, AB. "Aldehyde dehydrogenase polymorphisms: The role in myelodysplastic syndromes and acute myeloid leucemia". Paper presented in CIMAGO Meeting – Challenges in Oncobiology, 2020.
    Published
  28. Gomes, R.; Gonçalves AC; Jorge, J.; Alves, R.; Pereira, A.; Sarmento-RIbeiro, AB; Nascimento-Costa, JM. "IREB2 rs17483548 single nucleotide polymorphism is associated with colorectal cancer". Paper presented in CIMAGO Meeting – Challenges in Oncobiology, 2020.
    Published
  29. Figueiredo, D.; Jorge, J.; Alves, R.; Lapa, B.; Gonçalves AC; Sarmento-Ribeiro, AB. "NRF2 modulation as a new therapeutic approach in AML – In vitro studies". Paper presented in CIMAGO Meeting – Challenges in Oncobiology, 2020.
    Published
  30. Carda, JP; Alves, R.; Jorge, J.; Duarte, S.; Pereira, A.; Ribeiro, IP; Gonçalves AC; Carreira, IM; Sarmento-Ribeiro, AB. "Epigenetics in chronic lymphocytic leukemia - Role in pathogenesis and treatment". Paper presented in CIMAGO Meeting – Challenges in Oncobiology, 2020.
    Published
  31. Magalhães, N.; Roque, D.; Costa, MI; Gomes, E.; Jorge, J.; Alves, R.; Lapa, B.; Gonçalves AC; Sarmento-Ribeiro, AB. "Therapeutic effect of Oltipraz in acute lymphoblastic leukemia – Preliminary in vitro studies.". Paper presented in CIMAGO Meeting – Challenges in Oncobiology, 2020.
    Published
  32. Costa, MI; Magalhães, N.; Roque, D.; Gomes, E.; Alves, R.; Jorge, J.; Lapa, B.; et al. "Zinc as a genoprotective player of DNA damage response – Preliminary results". Paper presented in CIMAGO Meeting – Challenges in Oncobiology, 2020.
    Published
  33. Lapa, B.; Alves, R.; Jorge, J.; Cortesão, E.; Pereira, A.; Ribeiro, L.; Gonçalves AC; Sarmento-Ribeiro, AB. "EPO-EPOR axis as a prognostic and drug response biomarker in myelodysplastic syndrome - Preliminary results". Paper presented in CIMAGO Meeting - Challenges in Oncobiology, 2020.
    Published
  34. Oliveira, AC; Adão, DA; Pires, LM; Ribeiro, IP; Gonçalves AC; Paiva, A; Geraldes, C; et al. "Genomic characterization of chronic lymphocytic leukaemia and multiple myeloma patients: aCGH contribution.". Paper presented in 23rd Annual Meeting of the Portuguese Society of Human Genetics, 2020.
    Published
  35. Alves, R.; Gonçalves AC; Jorge, J.; Marques, G.; Barbosa Ribeiro, A.; Tenreiro, R.; Coucelo, M.; et al. "Genetic variability of influx and efflux transporters: the impact on susceptibility to chronic myeloid leukemia development". Paper presented in 53rd Annual Scientific Meeting of the European Society for Clinical Investigation, Coimbra, 2019.
    Published
  36. Jesus, N.; Jorge, J.; Alves, R.; Gonçalves AC; Sarmento-Ribeiro, AB. "Metformin and sirolimus as new treatment Options in childhood acute lymphoblastic Leukemia". Paper presented in 14th YES Meeting, Porto, 2019.
    Published
  37. Andrade, D.; Jorge, J.; Alves, RS; Marini, S.; Carda, JP; Gonçalves AC; Sarmento-Ribeiro, AB. "Dna methyltransferases gene expression levels in chronic lymphocytic leukemia - impact in development, diagnosis and prognosis". Paper presented in 24th European Hematology Association Congress, Amsterdam, 2019.
    Published
  38. Alves, RS; McArdle, S.; Vadakekolathu, J.; Gonçalves AC; Freitas-Tavares, P.; Pereira, A.; Almeida, AM; Sarmento-Ribeiro, AB; Rutella, S.. "Immune system and chronic myeloid leukemia: the impact of tyrosine kinase inhibitors". Paper presented in 24th European Hematology Association Congress, Amsterdam, 2019.
    Published
  39. Lapa, B.; Jorge, J.; Alves, RS; Pires, AS; Abrantes, AM; Coucelo, M.; Abrunhosa, A.; et al. "Glycolysis versus oxidative phosphorylation – potential therapeutic targets in aml". Paper presented in 24th European Hematology Association Congress, Amsterdam, 2019.
    Published
  40. Alves, RS; Gonçalves AC; Jorge, J.; Marques, G.; Barbosa Ribeiro, A.; Tenreiro, R.; Coucelo, M.; et al. "Influx/efflux transporters in chronic myeloid leukemia: the influence of genetic variants on susceptibility and drug response". Paper presented in 24th European Hematology Association Congress, Amsterdam, 2019.
    Published
  41. Lima, J.; Jorge, J.; Alves, RS; Gonçalves AC; Sarmento-Ribeiro, AB. "Therapeutic potencial of gambogic acid and silibinin in acute myeloblastic leukemia – in vitro studies". Paper presented in 24th European Hematology Association Congress, Amsterdam, 2019.
    Published
  42. Nascimento, T.; Adão, D.; Oliveira, A.; Pires, LM; Alves, RS; Jorge, J.; Ribeiro, IP; et al. "Genomic characterization of chronic lymphocytic leukemia and multiple myeloma: role of array comparative genomic hybridization (aCGH)". Paper presented in 24th European Hematology Association Congress, Amsterdam, 2019.
    Published
  43. Marques, I; Abrantes, AM; Pires, AS; Neves, AR; Tavares, NT; Caramelo, F; Tavares-Silva, E; et al. "The radiobiological effects of Radium-223 in metastatic prostate cancer cells". Paper presented in European Urology Supplements, 2019.
    Published
  44. Gonçalves AC; Macedo, B.; Alves, R.; Jorge, J.; Barbosa Ribeiro, A.; Marques, G.; Jorge, L.; Cortesão, E.; Sarmento-Ribeiro, AB. "Aldehyde dehydrogenases as potential biomarkers in myeloid neoplasias". Paper presented in CIMAGO Annual Scientific Meeting, Coimbra, 2018.
    Published
  45. Martins, R.; Nemésio, R.; Cardoso, K.; Oliveira, R.; Constâncio, V.; Calvão, J.; Gonçalves AC; et al. "Impact of splenic artery ligation after alpps on liver viability, regeneration and function - outcomes of an experimental study in animal model". Paper presented in CIMAGO Annual Scientific Meeting, Coimbra, 2018.
    Published
  46. Santos, AL; Santos, L.; Santo, R.; Teixeira, P.; Pires, S.; Abrantes, AM; Gonçalves AC; et al. "Radiation effects on human cell lines of osteosarcoma and retinoblastoma". Paper presented in CIMAGO Annual Scientific Meeting, Coimbra, 2018.
    Published
  47. Santo, R.; Santos, AL; Teixeira, P.; Pires, S.; Abrantes, AM; Gonçalves AC; Rocha, C.; et al. "Cellular response to ionizing radiation: in vitro studies on human prostate cancer cell lines". Paper presented in CIMAGO Annual Scientific Meeting, Coimbra, 2018.
    Published
  48. Alves, R.; Gonçalves AC; Jorge, J.; Almeida, A.; Sarmento-Ribeiro, AB. "Elacridar as a modulator of imatinib resistance". Paper presented in CIMAGO Annual Scientific Meeting, Coimbra, 2018.
    Published
  49. Alves, R.; Gonçalves AC; Jorge, J.; Luís, D.; Ribeiro, A.; Marques, G.; Jorge, L.; et al. "MicroRNAs profile in CML – A potential biomarker to imatinib response". Paper presented in CIMAGO Annual Scientific Meeting, Coimbra, 2018.
    Published
  50. Santos, D.; Alves, R.; Gonçalves AC; Jorge, J.; Catarino, S.; Girão, H.; Melo, JB; Sarmento-Ribeiro, AB. "The potential therapeutic effect of heat sock protein 90 inhibition in chronic myeloid leukemia". Paper presented in CIMAGO Annual Scientific Meeting, Coimbra, 2018.
    Published
  51. Neves, J.; Jorge, J.; Alves, R.; Gonçalves AC; Sarmento-Ribeiro, AB. "Parthenolide as a new therapeutic approach in acute lymphoblastic leukemia". Paper presented in CIMAGO Annual Scientific Meeting, Coimbra, 2018.
    Published
  52. Ribau, B.; Jorge, J.; Alves, R.; Ribeiro, IP; Carreira, IM; Gonçalves AC; Sarmento-Ribeiro, AB. "Epigenetic modulators in B cell acute lymphoblastic leukemia". Paper presented in CIMAGO Annual Scientific Meeting, Coimbra, 2018.
    Published
  53. Ferreira, C.; Jorge, J.; Alves, R.; Gonçalves AC; Sarmento-Ribeiro, AB. "Conserved embryonic signaling pathways inhibitors as new therapeutic strategies in B-cell neoplasms". Paper presented in CIMAGO Annual Scientific Meeting, Coimbra, 2018.
    Published
  54. Duarte, A.; Graça, S.; Salvada, A.; Teixeira, PC; Pires, S.; Marques, I.; Costa, EFD; et al. "FADU response to cisplatin, docetaxel and 5-fluorouracil - In vitro preliminary results". Paper presented in CIMAGO Annual Scientific Meeting, Coimbra, 2018.
    Published
  55. Jorge, J.; Pires, A.; Alves, R.; Gonçalves AC; Sarmento-Ribeiro, AC. "Can g-secretase inhibitors be a good therapeutic approach in acute lymphoblastic leukaemia". Paper presented in CIMAGO Annual Scientific Meeting, Coimbra, 2018.
    Published
  56. Rodrigues, JM; Ribeiro, IP; Abrantes, AM; Gonçalves AC; Marques, IA; Lourenço, AS; Casalta-Lopes, J.; et al. "HNSCC cell lines with different radiosensitivities have distinct responses to radiation treatment?". Paper presented in CIMAGO Annual scientific Meeting, Coimbra, 2018.
    Published
  57. Domingues, F.; Brás, M.; Silva, N.; Gonçalves AC; Pereira, A.; Santos, L.. "Assessment of malnutrition risk in hospitalized patients". Paper presented in CIMAGO Annual scientific Meeting, Coimbra, 2018.
    Published
  58. Marto, CM; Laranjo, M.; Paula, A.; Abrantes, AM; Gonçalves AC; Sarmento-Ribeiro, AB; Cabrita, A.; Botelho, MF; Carrilho, E.. "Gingival fibroblasts can deddiferentiate into stem-like cells". Paper presented in CIMAGO Annual scientific Meeting, Coimbra, 2018.
    Published
  59. Lopes, S.; Garcia, C.; Ribeiro, IP; Bertoquini, S.; Gonçalves AC; Figueiredo, D.; Viana, JL; et al. "Inflammation, cardiorespiratory fitness and blood pressure in patients with resistant hypertension". Paper presented in CIMAGO Annual scientific Meeting, Coimbra, 2018.
    Published
  60. Santos, D.; Alves, R.; Gonçalves AC; Jorge, J.; Girão, H.; Catarino, S.; Barbosa De Melo, J.; Sarmento-Ribeiro, AB. "Alvespimycin is a promising drug in resistant Chronic Myeloid Leukemia". Paper presented in 13th YES meeting, Porto, 2018.
    Published
  61. Santos, P.; Murtinho, D.; Pires, S.; Araújo, J.; Martins, R.; Abrantes, M.; Gonçalves AC; Botelho, F.; Serra, ME. "Synthesis of novel Ru (II) and Ru (III) salen and salan complexes and their cytotoxic effect in breast and colorectal cancer cell lines". Paper presented in 13th YES meeting, Porto, 2018.
    Published
  62. Araújo, J.; Serra, ME; Pires, AS; Santos, P.; Martins, R.; Abrantes, AM; Gonçalves AC; Botelho, MF; Murtinho, D.. "Cu(II) complexes derived from imidazole show cytotoxic activity in breast and colorectal cancers". Paper presented in 13th YES Meeting, Porto, 2018.
    Published
  63. Lapa, B.; Jorge, J.; Alves, R.; Pires, AS; Abrantes, AM; Coucelo, M.; Botelho, MF; Gonçalves AC; Sarmento-Ribeiro, AB. "Metabolism as a therapeutic target in acute myeloid leukemic – glycolysis or oxidative phosphorylation?". Paper presented in 13th YES meeting, Porto, 2018.
    Published
  64. Teles, F.; Marto, CM; Laranjo, M.; Paula, A.; Gonçalves AC; Botelho, MF; Carrilho, E.. "Microenvironment influence on stem-like cells differentiation". Paper presented in 13th YES meeting, Coimbra, 2018.
    Published
  65. Oliveira, N.; Vitorino, M.; Santo, R.; Teixeira, P.; Pires, S.; Abrantes, AM; Gonçalves AC; et al. "Ionizing radiation effects in a bladder and an esophageal cancer cell lines". Paper presented in 4th IPLeiria’s International Health Congress, Leiria, 2018.
    Published
  66. Alves, RS; Gonçalves AC; Jorge, J.; Almeida, A.; Sarmento-Ribeiro, AB. "PgP and BCRP inhibitor as a modulator of imatinib resistance". Paper presented in 23rd Congress of EHA, Stockholm, 2018.
    Published
  67. Alves, RS; Gonçalves AC; Jorge, J.; Luís, D.; Ribeiro, A.; Marques, G.; Jorge, L.; et al. "Imatinib response and microRNAs profile in CML- A biomarker for drug response". Paper presented in 23rd Congress of EHA, Stockholm, 2018.
    Published
  68. Jorge, J.; Pires, A.; Alves, RS; Gonçalves AC; Sarmento-Ribeiro, AB. "NOTCH pathway as a therapeutic target in acute lymphoblastic leukemia". Paper presented in 23rd Congress of EHA, Stockholm, 2018.
    Published
  69. Ribau, B.; Jorge, J.; Alves, R.; Ribeiro, IP; Marques Carreira, I.; Gonçalves AC; Sarmento-Ribeiro, AB. "Epigenetic modulators show in vitro therapeutic potential to treat B cell acute lymphoblastic leukemia". Paper presented in 23rd Congress of EHA, Stockholm, 2018.
    Published
  70. Santos, D.; Alves, R.; Gonçalves AC; Jorge, J.; Girão, H.; Catarino, S.; Barbosa De Melo, J.; Sarmento-Ribeiro, AB. "Heat sock protein 90 inhibition as a potential therapeutic target in chronic myeloid leukemia". Paper presented in 23rd Congress of EHA, Stockholm, 2018.
    Published
  71. Neves, J.; Jorge, J.; Alves, R.; Gonçalves AC; Sarmento-Ribeiro, AB. "Parthenolide, an NF-kB inhibitor, induce cell death and suppress cell proliferation in lymphoid malignancies". Paper presented in 23rd Congress of EHA, Stockholm, 2018.
    Published
  72. Gonçalves AC; Macedo, B.; Barbosa Ribeiro, A.; Alves, R.; Jorge, J.; Marques, G.; Jorge, L.; Cortesão, E.; Sarmento-Ribeiro, AB. "Diagnostic potential of aldehyde dehydrogenases isoenzymes in MDS and AML". Paper presented in 23rd Congress of EHA, Stockholm, 2018.
    Published
  73. Ferreira, C.; Jorge, J.; Alves, R.; Gonçalves AC; Sarmento-Ribeiro, AB. "WNT/¿-catenin and hedgehog inhibitors as therapeutic approaches in B-cell neoplasms". Paper presented in 23rd Congress of EHA, Stockholm, 2018.
    Published
  74. Silva-Teixeira, R.; Laranjo, M.; Almeida-Ferreira, C.; Brites, G.; Abrantes, AM; Gonçalves AC; Sarmento-Ribeiro, AB; Caramelo, F.; Botelho, MF. "Cold atmospheric plasma: a potentially selective and non-inflammatory anti-cancer therapy". Paper presented in 25th Biennial Congress of the European Association for Cancer Research, Amsterdam, 2018.
    Published
  75. Marto, CM; Laranjo, M.; Paula, A.; Abrantes, AM; Gonçalves AC; Ribeiro, AB; Cabrita, A.; Botelho, MF; Carrilho, E.. "Gingival Fibroblast Dedifferentiation: An Option in Regenerative Dentistry?". Paper presented in 105th FDI World Dental Congress, 2017.
    Published
  76. Macedo, B.; Jorge, J.; Alves, R.; Gonçalves AC; Sarmento-Ribeiro, AB. "ALDHs as potential biomarkers in myeloid neoplasms – Preliminary study". Paper presented in 12th YES meeting, Porto, 2017.
    Published
  77. Gonçalves AC; Ribau, B.; Jorge, J.; Alves, R.; Ribeiro, IP; Carreira, IM; Sarmento-Ribeiro, AB. "Epigenetic modifications as targets to new therapies for Chronic Lymphocytic leukaemia – A preliminary study". Paper presented in 12th YES meeting, Porto, 2017.
    Published
  78. Neves, J.; Jorge, J.; Alves, R.; Gonçalves AC; Sarmento-Ribeiro, AB. "Cytotoxic effects of parthenolide on lymphoid malignancies’ cell lines". Paper presented in 12th YES meeting, Porto, 2017.
    Published
  79. Ferreira, C.; Jorge, J.; Alves, R.; Gonçalves AC; Sarmento-Ribeiro, AB. "WNT/b-catenin and Hedgehog signaling pathways as therapeutic targets in B-cell neoplasms". Paper presented in 12th YES meeting, Porto, 2017.
    Published
  80. Cortesão, E.; Gonçalves AC; Tenreiro, AR; Ribeiro, A.; Geraldes, C.; Costa e Silva, N.; Ribeiro, L.; Nascimento-Costa, JM; Sarmento-Ribeiro, AB. "Progression score for acute leukemia – A new prognostic score in MDS?". Paper presented in 22nd Congress of EHA, Madrid, 2017.
    Published
  81. Marini, S.; Carda, J.; Antunes, J.; Ribeiro, A.; Tenreiro, R.; Ruzickova, L.; Alves, R.; et al. "Role of KEAP1-NRF2 pathway genetic variability in the susceptibility and prognosis of patients with chronic lymphocytic leukemia". Paper presented in 22nd Congress of EHA, Madrid, 2017.
    Published
  82. Melo, MS; Balanco, L.; Barbosa Ribeiro, A.; Gonçalves AC; Alves, R.; Cortesão, E.; Ribeiro, L.; Mota-Vieira, L.; Sarmento-Ribeiro, AB. "Genetic variants of MSH3 and BLM genes may influence myelodysplastic syndrome susceptibility and prognosis". Paper presented in 22nd Congress of EHA, Madrid, 2017.
    Published
  83. Gonçalves AC; Balanco, L.; Melo, MS; Gonçalves, AC; Alves, R.; Geraldes, C.; Cortesão, E.; et al. "Influence of XRCC5, XRCC4, NFkB2, and BIRC5 genes polymorphisms in the risk and prognosis of monoclonal gammopathies". Paper presented in 22nd Congress of EHA, Madrid, 2017.
    Published
  84. Alves, R.; Gonçalves AC; Couceiro, P.; Rodrigues-Santos, P.; Freitas-Tavares, P.; Ribeiro, L.; Almeida, AM; Sarmento-Ribeiro, AB. "The role of microRNAs in chronic myeloid leukemia therapeutic selection". Paper presented in 22nd Congress of EHA, Madrid, 2017.
    Published
  85. Geraldes, C.; Gonçalves AC; Alves, R.; Cortesão, E.; Ribeiro, L.; Nascimento-Costa, JM; Sarmento-Ribeiro, AB. "Prognostic relevance of VEGF and VEGFR expression in CD138+/CD19- and CD138+/CD19+ plasma cells from patients with monoclonal gammopathies". Paper presented in 22nd Congress of EHA, Madrid, 2017.
    Published
  86. Alves, T.; Pires, A.; Jorge, J.; Alves, R.; Gonçalves AC; Sarmento-Ribeiro, AB. "The Wnt Pathway As A Potential Therapeutic Target In Acute Myeloid Leukemia". Paper presented in 11th YES meeting, Porto, 2016.
    Published
  87. Brites, G.; Serambeque, B.; Laranjo, M.; Chohfi de Miguel, G.; Almeida, N.; Caetano Oliveira, R.; Serra, AC; et al. "Synergistic Effect Of Photodynamic Therapy In Combination With Chemotherapy: An Option In Osteosarcoma". Paper presented in 11th YES meeting, Coimbra, 2016.
    Published
  88. Almeida, N.; Laranjo, M.; Brites, G.; Carvalho, MJ; Serra, AC; Abrantes, M.; Pineiro, M.; et al. "The Combined Effect Of Photodynamic Therapy And Acetylsalicylic Acid Against Colorectal Cancer: An In Vitro And In Vivo Study". Paper presented in 11th YES meeting, Porto, 2016.
    Published
  89. Serambeque, B.; Brites, G.; Laranjo, M.; Chofi de Miguel, G.; Serra, AC; Pineiro, M.; Abrantes, M.; et al. "Evaluation of the cytotoxic response of photodynamic therapy in combination with doxorubicin and methotrexate in osteosarcoma". Paper presented in 5th CIMAGO Congress, Coimbra, 2016.
    Published
  90. Geraldes, C.; Gonçalves AC; Alves, R.; Cortesão, E.; Ribeiro, L.; Nascimento-Costa, JM; Sarmento-Ribeiro, AB. "IS NF-KB EXPRESSION RELEVANT IN MULTIPLE MYELOMA PATIENTS TREATED WITH BORTEZOMIB AS FRONTLINE REGIMEN?". Paper presented in 5th CIMAGO Congress, Coimbra, 2016.
    Published
  91. Almeida, N.; Laranjo, M.; Serra, AC; Abrantes, M.; Pineiro, M.; Gonçalves AC; Casalta-Lopes, J.; Sarmento-Ribeiro, AB; Botelho, MF. "THE SYNERGIC EFFECT OF PHOTODYNAMIC THERAPY AND ACETYLSALICYLIC ACID IN COLORECTAL AND ESOPHAGUS CANCER CELLS". Paper presented in 5th CIMAGO congress, Coimbra, 2016.
    Published
  92. Gonçalves AC; Alves, R.; Couceiro, P.; Rodrigues-Santos, P.; Freitas-Tavares, P.; Brás, M.; Pereira, A.; et al. "POLYMORPHISMS IN OXIDATIVE STRESS RELATED GENES AS PROGNOSTIC AND THERAPEUTIC BIOMARKERS IN CHRONIC MYELOID LEUKEMIA". Paper presented in 5th CIMAGO congress, Coimbra, 2016.
    Published
  93. Petronilho, S.; Alves, R.; Coucelo, M.; Ribeiro, L.; Gonçalves AC; Sarmento-Ribeiro, AB. "THERAPEUTIC POTENTIAL OF THE SPLICING INHIBITOR PLADIENOLIDE B IN ACUTE MYELOID LEUKEMIA – AN IN VITRO STUDY". Paper presented in 5th CIMAGO Congress, Coimbra, 2016.
    Published
  94. Costa, NS; Marques, BA; Alves, R.; Pires, A.; Gonçalves AC; Sarmento-Ribeiro, AB. "Buparlisib, a new therapeutic approach in myeloid malignancies". Paper presented in th CIMAGO Congress, Coimbra, 2016.
    Published
  95. Alves, R.; Gonçalves AC; Couceiro, P.; Rodrigues-Santos, P.; Freitas-Tavares, P.; Ribeiro, L.; Almeida, A.; Sarmento-Ribeiro, AB. "EVEROLIMUS AS A NEW THERAPEUTIC OPTION IN CML RESISTANT TO TKI – A PRELIMINARY STUDY". Paper presented in 5th CIMAGO congress, Coimbra, 2016.
    Published
  96. Domingues, C.; Gonçalves AC; Alves, R.; Dourado, M.; Sarmento-Ribeiro, AB. "SILIBININ AND GAMBOGIC ACID INDUCE REACTIVE OXYGEN SPECIES PRODUCTION AND CELL DEATH IN T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA CELLS". Paper presented in 5th CIMAGO Congress, Coimbra, 2016.
    Published
  97. Coucelo, M.; Pires, A.; Gonçalves AC; Simões, AT; Azevedo, J.; Brito, MJ; Silva, S.; Ribeiro, ML; Sarmento-Ribeiro, AB. "THE ROLE OF WNT AND HEDGEHOG SIGNALING PATHWAYS AS NOVEL PROGNOSTIC MARKERS AND THERAPEUTIC TARGETS IN PEDIATRIC B CELLS ACUTE LYMPHOBLASTIC LEUKEMIA – A PRELIMINARY STUDY". Paper presented in 5th CIMAGO congress, Coimbra, 2016.
    Published
  98. Pires, AS; Marques, CR; Encarnação, JC; Casalta-Lopes, JE; Gonçalves AC; Abrantes, AM; Sarmento-Ribeiro, AB; Botelho, MF. "Ascorbic acid and conventional chemotherapeutic agents synergistically inhibit colorectal cancer cells proliferation and tumor growth". Paper presented in 5th CIMAGO congress, Coimbra, 2016.
    Published
  99. Marques, BA; Costa, NS; Alves, R.; Pires, A.; Gonçalves AC; Sarmento-Ribeiro, AB. "SHIKONIN INDUCE APOPTOSIS THROUGH OXIDATIVE STRESS IN DIFFERENT HEMATOLOGICAL NEOPLASIAS". Paper presented in 5th CIMAGO Congress, Coimbra, 2016.
    Published
  100. Jorge, J.; Gonçalves AC; Cortesão, E.; Geraldes, C.; Pires, A.; Fernandes, S.; Alves, R.; Ribeiro, L.; Ribeiro, AB. "NFE2L2 AND KEAP1 GENE EXPRESSION ANALYSIS IN HEMATOLOGICAL MALIGNANCIES – CLINICAL IMPLICATIONS". Paper presented in 5th CIMAGO congress, Coimbra, 2016.
    Published
  101. Geraldes, C.; Gonçalves AC; Alves, R.; Cortesão, E.; Ribeiro, L.; Nascimento-Costa, JM; Sarmento-Ribeiro, AB. "VEGF EXPRESSION IN CD138+/CD19- AND CD138+/ CD19+ PLASMA CELLS FROM PATIENTS WITH MONOCLONAL GAMMOPATHIES". Paper presented in 5th CIMAGO congress, Coimbra, 2016.
    Published
  102. Laranjo, M.; Almeida, N.; Serra, A.; Abrantes, AM; Pineiro, M.; Gonçalves AC; Casalta-Lopes, J.; Sarmento-Ribeiro, AB. "The role of reactive oxygen species in photodynamic therapy combined with acetylsalicylic acid in colon and esophagus cancer cells". Paper presented in 24th Biennial EACR Congress, Manchester, 2016.
  103. Silva-Teixeira, R.; Laranjo, M.; Brites, G.; Abrantes, AM; Rodrigues, T.; Gonçalves AC; Raquel, S.; et al. "Cold atmoshperic plasma as an approach to retinoblastoma". Paper presented in 24th Biennial EACR Congress, Manchester, 2016.
    Published
  104. Pires, AS; Marques, CR; Encarnação, J.; Casalta-Lopes, J.; Gonçalves AC; Abrantes, AM; Sarmento-Ribeiro, AB; Botelho, MF. "Ascorbic acid and conventional chemotherapeutic agents synergistically inhibit colorectal cancer cells proliferation and tumor growth". Paper presented in 24th Biennial EACR Congress, Manchester, 2016.
    Published
  105. Almeida, N.; Laranjo, M.; Serra, A.; Abrantes, AM; Pineiro, M.; Gonçalves AC; Casalta-Lopes, J.; Sarmento-Ribeiro, AB; Botelho, MF. "Photodynamic therapy combined with acetylsalicylic acid: the mechanisms involved in colon and esophagus cancer cell death". Paper presented in 24th Biennial EACR Congress, Manchester, 2016.
    Published
  106. Serambeque, B.; Brites, G.; Laranjo, M.; Chohfi de Miguel, G.; Serra, A.; Pineiro, M.; Abrantes, AM; et al. "Combination of photodynamic therapy with doxorubicin in osteosarcoma: Cell death and the role of oxidative stress". Paper presented in 24th Biennial EACR Congress, Manchester, 2016.
    Published
  107. Laranjo, M.; Teixo, R.; Abrantes, AM; Gonçalves AC; Sarmento-Ribeiro, AB; Pineiro, M.; Serra, A.; Oliveira, S.; Botelho, MF. "Photodynamic therapy in EGFR targeted nanoparticles for lung cancer". Paper presented in 24th Biennial EACR Congress, Manchester, 2016.
    Published
  108. Mendes, F.; Domingues, C.; Schukg, S.; Abrantes, AM; Gonçalves AC; Sales, T.; Teixo, R.; et al. "The molecular effects induced by single shot irradiation on a diffuse large B cell lymphoma cell line". Paper presented in 3rd IPLeiria’s International Health Congress, Leiria, 2016.
    Published
  109. Gonçalves AC; Alves, R.; Couceiro, P.; Rodrigues-Santos, P.; Freitas-Tavares, P.; Pereira, A.; Ribeiro, L.; et al. "GENETIC VARIABILITY OF OXIDATIVE STRESS AND DNA REPAIR GENES POTENTIAL PROGNOSTIC AND THERAPEUTIC BIOMARKERS IN CHRONIC MYELOID LEUKEMIA". Paper presented in 21st Congress of the European Hematology Association, Copenhagen, 2016.
    Published
  110. Pires, A.; Jorge, J.; Alves, R.; Gonçalves AC; Sarmento-Ribeiro, AB. "THE TERAPEUTIC POTENTIAL OF EMBRIONARY SIGNALING PATHWAYS INHIBITION IN ACUTE LYMPHOBLASTIC LEUKEMIA". Paper presented in 21st Congress of the European Hematology Association, Copenhagen, 2016.
    Published
  111. Coucelo, M.; Pires, A.; Gonçalves AC; Simões, AT; Azevedo, J.; Brito, MJ; Silva, S.; Ribeiro, ML; Sarmento-Ribeiro, AB. "Evaluation of WNT and HEDGEHOG signaling pathways in pediatric B acute lymphoblastic leukemia - A preliminary study". Paper presented in 21st Congress of the European Hematology Association, Copenhagen, 2016.
    Published
  112. Alves, RS; Gonçalves AC; Couceiro, P.; Rodrigues-Santos, P.; Freitas-Tavares, P.; Ribeiro, L.; Almeida, A.; Sarmento-Ribeiro, AB. "MTOR INHIBITION IN CML: A NEW THERAPEUTIC OPTION". Paper presented in 21st Congress of the European Hematology Association, Copenhagen, 2016.
    Published
  113. Jorge, J.; Gonçalves AC; Cortesão, E.; Geraldes, C.; Gomes, B.; Pires, A.; Fernandes, S.; et al. "NFE2L2,KEAP1AND NQO1GENE EXPRESSION IN MYELODYSPLASTIC SYNDROME AND MONOCLONAL GAMMOPATHIES-CLINICAL IMPLICATIONS". Paper presented in 21st Congress of the European Hematology Association, Copenhagen, 2016.
    Published
  114. Ferreira, SM; Abrantes, AM; Laranjo, M.; Casalta-Lopes, J.; Gonçalves AC; Sarmento-Ribeiro, AB; Zeevaart, J.; et al. "Synthesis, preparation and characterization of 99mTc-PEI-MP: a potential radiopharmaceutical for the diagnosis of bladder cancer". Paper presented in Annual Congress of the European Association of Nuclear Medicine, Barcelona, 2016.
    Published
  115. Ferreira, SM; Abrantes, AM; Laranjo, M.; Casalta-Lopes, J.; Gonçalves AC; Sarmento-Ribeiro, AB; Zeevaart, J.; et al. "Diagnosis with resource to image of bladder cancer: an in vivo evaluation of 99mTc-PEI-MP". Paper presented in Annual Congress of the European Association of Nuclear Medicine, Barcelona, 2016.
    Published
  116. Gonçalves, TJ; Pires, AS; Encarnação, JC; Casalta, JE; Gonçalves AC; Abrantes, AM; Sarmento-Ribeiro, AB; et al. "Butirato vs Glicose: poderá a nossa dieta atenuar as alterações associadas ao efeito Warburg nas células tumorais?". Paper presented in XXXVI Congresso Nacional de Cirurgia, Coimbra, 2016.
    Published
  117. Almeida, N.; Laranjo, M.; Serra, AC; Abrantes, M.; Pineiro, M.; Gonçalves AC; Casalta-Lopes, J.; et al. "Terapia Fotodinâmica em combinação com ácido acetilsalicílico para o tratamento de cancro coloretal e esofágico". Paper presented in XXXVI Congresso Nacional de Cirurgia, Coimbra, 2016.
    Published
  118. Geraldes, C.; Gonçalves AC; Alves, R.; Roque, A.; Costa, JM; Sarmento-Ribeiro, AB. "New Targeted Drugs in Multiple Myeloma Therapy - in Vitro Studies". Paper presented in 15th International Myeloma Workshop, Rome, 2015.
    Published
  119. Brito, A.; Fernandes, A.; Abrantes, AM; Laranjo, M.; Gonçalves AC; Sarmento-Ribeiro, AB; Botelho, MF; Tralhão, JG; Castro-Sousa, F.. "Cholangiocarcinoma treatment; could iodine-131 be an option?". Paper presented in 101st American College of Surgeons Clinical Congress, Chicago, 2015.
    Published
  120. Geraldes, C.; Gonçalves AC; Alves, R.; Cortesão, E.; Ribeiro, ML; Nascimento-Costa, JM; Sarmento-Ribeiro, AB. "Vascular Endothelial Growth Factor Expression in CD138+/CD19- and CD138+/CD19+ Plasma Cells in Monoclonal Gammopathies and Impact on Multiple Myeloma Prognosis". Paper presented in 57th American Society of Hematology Annual Meeting, Orlando, 2015.
    Published
  121. Gonçalves AC; Alves, R.; Cortesão, E.; Freitas-Tavares, P.; Carda, JP; Rito, L.; Couceiro, P.; et al. "Genetic variability of DNMTs and folate/ methionine metabolism genes – Role in methylation status and myeloid neoplasias risk". Paper presented in 29ª Reunião-4º Congresso do CIMAGO, Coimbra, 2015.
    Published
  122. Gonçalves AC; Geraldes, C.; Alves, R.; Cortesão, E.; Ribeiro, L.; Nascimento-Costa, JM; Sarmento-Ribeiro, AB. "Is tumor necrosis factor-related apoptosis inducing ligand and death receptors relevant in monoclonal gammopathies?". Paper presented in 29ª Reunião-4º Congresso do CIMAGO, Coimbra, 2015.
    Published
  123. Gonçalves AC; Alves, R.; Pires, A.; Jorge, J.; Baldeiras, I.; Cortesão, E.; Carda, JP; et al. "The interplay between oxidative stress and DNA methylation – Role in development, diagnosis and prognosis of myeloid neoplasias". Paper presented in 29ª Reunião-4º Congresso do CIMAGO, Coimbra, 2015.
    Published
  124. Cortesão, E.; Gonçalves AC; Geraldes, C.; Pereira, A.; Ribeiro, L.; Nascimento-Costa, JM; Sarmento-Ribeiro, AB. "Characterization of leukemic stem cells in patients with MDS". Paper presented in 29ª Reunião-4º Congresso do CIMAGO, Coimbra, 2015.
    Published
  125. Pereira, A.; Gonçalves AC; Pires, A.; Silva, D.; Matafome, P.; Seiça, R.; Silva, N.; Sarmento-Ribeiro, AB; Nascimento-Costa, JM. "Adipocytokines gene expression in colorectal cancer tissues – Correlation with protein serum levels". Paper presented in 29ª Reunião-4º Congresso do CIMAGO, Coimbra, 2015.
    Published
  126. Fernandes, S.; Jorge, J.; Gonçalves AC; Alves, R.; Pires, A.; Veiga, S.; Cortesão, E.; et al. "Influence of the ABC transporters’ genetic profiles in the development of myeloid neoplasias". Paper presented in 29ª Reunião-4º Congresso do CIMAGO, Coimbra, 2015.
    Published
  127. Oliveira, L.; Geraldes, C.; Gonçalves AC; Pais, AS; Cortesão, E.; Matafome, P.; Seiça, R.; et al. "The role of adipocytokines in monoclonal gammopathies – A preliminary study". Paper presented in 29ª Reunião-4º Congresso do CIMAGO, Coimbra, 2015.
    Published
  128. Marques, BA; Costa, NS; Alves, R.; Pires, A.; Gonçalves AC; Sarmento-Ribeiro, AB. "The potential therapeutic effect of shikonin in different hematological neoplasias". Paper presented in 29ª Reunião-4º Congresso do CIMAGO, Coimbra, 2015.
    Published
  129. Gonçalves AC; Alves, R.; Pires, A.; Jorge, J.; Mota-Vieira, L.; Nascimento-Costa, JM; Sarmento-Ribeiro, AB. "Chronic exposure to oxidative stress inducers influence methylation status in normal and neoplastic hematological cells". Paper presented in 29ª Reunião-4º Congresso do CIMAGO, Coimbra, 2015.
    Published
  130. Costa, NS; Marques, BA; Alves, R.; Pires, A.; Gonçalves AC; Sarmento-Ribeiro, AB. "Buparlisib, another step in the quest to cure haematological malignancies". Paper presented in 29ª Reunião-4º Congresso do CIMAGO, Coimbra, 2015.
    Published
  131. Alves, R.; Geraldes, C.; Pires, A.; Gonçalves AC; Nascimento-Costa, JM; Sarmento-Ribeiro, AB. "Targetting intracellular signaling in multiple myeloma: the role of new drugs as therapeutic approaches". Paper presented in 29ª Reunião-4º Congresso do CIMAGO, Coimbra, 2015.
    Published
  132. Laranjo, M.; Teixo, R.; Abrantes, AM; Gonçalves AC; Sarmento-Ribeiro, AB; Pineiro, M.; Rocha-Gonsalves, AM; et al. "Nanodirect-PDT: EGFR targeted nanoparticles and photodynamic therapy for lung cancer". Paper presented in 29ª Reunião-4º Congresso do CIMAGO, Coimbra, 2015.
    Published
  133. Gonçalves, TJ; Pires, AS; Encarnação, JC; Casalta, JE; Gonçalves AC; Abrantes, AM; Sarmento-Ribeiro, AB; Carvalho, RA; Botelho, MF. "May our diet interfere with colon cancer aggressiveness provoked by warburg effect?". Paper presented in 29ª Reunião-4º Congresso do CIMAGO, Coimbra, 2015.
    Published
  134. Fernandes, AI; Abrantes, AM; Brito, AF; Ribeiro, AC; Laranjo, M.; Santos, K.; Gonçalves AC; et al. "Iodine-131: could be an option for cholangiocarcinoma treatment?". Paper presented in 29ª Reunião-4º Congresso do CIMAGO, Coimbra, 2015.
    Published
  135. Pires, AS; Marques, CR; Encarnação, JC; Gonçalves, TJ; Mamede, AC; Gonçalves AC; Abrantes, AM; Sarmento-Ribeiro, AB; Botelho, MF. "Ascorbic acid-induced cytotoxicity in three colon cancer cell lines". Paper presented in 29ª Reunião-4º Congresso do CIMAGO, Coimbra, 2015.
    Published
  136. Eulálio, F.; Martins, S.; Melo, E.; Costa, R.; Gonçalves AC; Ribeiro, IP; Sarmento-Ribeiro, AB; et al. "Resistance exercise at 70% of maximum resistance increases the circulating number of endothelial progenitor cells: Preliminary results". Paper presented in 29ª Reunião - 4º Congresso do CIMAGO, Coimbra, 2015.
    Published
  137. Casalta-Lopes, JE; Ferreira, A.; Laranjo, M.; Santos, K.; Abrantes, AM.; Cavaco, A.; Gonçalves AC; et al. "Different response profiles of radiosensitive and radioresistant colorectal cancer cell lines". Paper presented in 29ª Reunião - 4º Congresso do CIMAGO, Coimbra, 2015.
    Published
  138. Veiga, S.; Pires, A.; Alves, R.; Fernandes, S.; Gonçalves AC; Sarmento-Ribeiro, AB. "Relevance of microRNAs expression in response to targeted therapies in chromic myeloid leukemia". Paper presented in 29ª Reunião - 4º Congresso do CIMAGO, Coimbra, 2015.
    Published
  139. Gonçalves AC; Alves, R.; Pires, A.; Jorge, J.; Mota-Vieira, L.; Nascimento-Costa, JM; Sarmento-Ribeiro, AB. "Exposure to ROS induces DNA damage and influences DNA methylation in normal and malignant hematological cell lines". Paper presented in 20th Congress Of The European Hematology Association, Vienna, 2015.
    Published
  140. Gonçalves AC; Alves, R.; Cortesão, E.; Freitas-Tavares, P.; Carda, JP; Rito, L.; Couceiro, P.; et al. "Polymorphisms of DNMTs and folate/methionine metabolism genes influence DNA methylation, genetic susceptibility and prognosis of myeloid neoplasia patients". Paper presented in 20th Congress Of The European Hematology Association, Vienna, 2015.
    Published
  141. Geraldes, C.; Gonçalves AC; Alves, R.; Cortesão, E.; Ribeiro, L.; Nascimento-Costa, JM; Sarmento-Ribeiro, AB. "Tumor necrosis factor-related apoptosis-inducing ligand and death receptors: Relevance in the pathogenesis of monoclonal gammopathies". Paper presented in 20th Congress Of The European Hematology Association, Vienna, 2015.
    Published
  142. Veiga, S.; Pires, A.; Alves, R.; Fernandes, S.; Matafome, P.; Seiça, R.; Gonçalves AC; Sarmento-Ribeiro, AB. "The role of microRNAs in response to new targeted therapies in chronic myeloid leukemia". Paper presented in 20th Congress Of The European Hematology Association, Vienna, 2015.
    Published
  143. Geraldes, C.; Gonçalves AC; Alves, R.; Cortesão, E.; Ribeiro, L.; Nascimento-Costa, JM; Sarmento-Ribeiro, AB. "Impact of NF-kB expression in the prognosis of multiple myeloma patients treated with bortezomib in frontline regimens". Paper presented in 20th Congress Of The European Hematology Association, Vienna, 2015.
    Published
  144. Cortesão, E.; Gonçalves AC; Geraldes, C.; Pereira, A.; Ribeiro, L.; Nascimento-Costa, JM; Sarmento-Ribeiro, AB. "Clinical relevance of IL-6 and TNF-alfa in the characterization of leukemic stem cells in MDS patients". Paper presented in 20th Congress Of The European Hematology Association, Vienna, 2015.
    Published
  145. Fernandes, S.; Gonçalves AC; Jorge, J.; Geraldes, C.; Alves, R.; Pires, A.; Veiga, S.; et al. "Influence of ABC transporters’ genetic profiles in the development of monoclonal gammopathies". Paper presented in 20th Congress Of The European Hematology Association, Vienna, 2015.
    Published
  146. Tenreiro, R.; Cortesão, E.; Ramos, S.; Pereira, M.; César, P.; Carda, J.; Gomes, M.; et al. "Prognosis in MDS – Can serum erythropoietin be of help?". Paper presented in 20th Congress Of The European Hematology Association, Vienna, 2015.
    Published
  147. Costa, BP; Sarmento-Ribeiro, AB; Gonçalves AC; Botelho, F.; Abrantes, AM.; Castro-Sousa, F.. "Tissular growth factors profile after teduglutide administration on an animal model of intestinal anastomosis". Paper presented in 37th European Society for Clinical Nutrition and Metabolism Congress, Lisboa, 2015.
    Published
  148. Costa, BP; Sarmento-Ribeiro, AB; Gonçalves AC; Botelho, MF; Abrantes, AM; Castro-Sousa, F.. "Response of putative intestinal epithelial stem cells to surgical injury and teduglutide administration on an animal model". Paper presented in 37th European Society for Clinical Nutrition and Metabolism Congress, Lisboa, 2015.
    Published
  149. Sarmento-Ribeiro, AB; Petronilho, S.; Alves, R.; Gonçalves AC; Coucelo, M.; Ribeiro, L.. "Therapeutic potential of the splicing inhibitor pladienolide B in erythroleukemia: in vitro evidence". Paper presented in LVII CONGRESO NACIONAL DE LA SOCIEDAD ESPAÑOLA DE HEMATOLOGÍA Y HEMOTERAPIA, Valencia, 2015.
    Published
  150. Teixo, R.; Laranjo, M.; Serra, A.; Pineiro, M.; Abrantes, M.; Gonçalves AC; Casalta-Lopes, J.; et al. "Photodynamic therapy in retinoblastoma : Cell proliferation and oxidative stress effects". Paper presented in 2nd IPLeiria Internacional Health Congress, Coimbra, 2014.
    Published
  151. Teixo, R.; Laranjo, M.; Serra, A.; Pineiro, M.; Abrantes, M.; Gonçalves AC; Casalta-Lopes, J.; et al. "Photodynamic therapy in retinoblastoma : Effects in cell viability, cell cycle and P53". Paper presented in 2nd IPLeiria Internacional Health Congress, Leiria, 2014.
    Published
  152. Mendes, F.; Sales, T.; Schugk, S.; Gonçalves AC; Sarmento, AB; Botelho, MF; Santos Rosa, M.. "Impact of ionizing radiation on lymphoma cell line – Cell death, BAX-BCL-2, P53 expression". Paper presented in 2nd IPLeiria Internacional Health Congress, Leiria, 2014.
    Published
  153. Mendes, F.; Sales, T.; Schugk, S.; Gonçalves AC; Sarmento, AB; Botelho, MF; Santos Rosa, M.. "Ionizing radiation induce DNA damage and cell cycle arrest in a lung cancer cell line". Paper presented in 2nd IPLeiria Internacional Health Congress, Leiria, 2014.
    Published
  154. Gonçalves AC; Encarnação, J.; Pires, AS; Gonçalves, T.; Abrantes, M.; Casalta, J.; Sarmento, AB; Botelho, MF. "Butyrate and irinotecan: A new approach for colon cancer". Paper presented in 2nd IPLeiria Internacional Health Congress, Leiria, 2014.
    Published
  155. Brito, AF; Abrantes, AM; Laranjo, M.; Gonçalves AC; Sarmento, AB; Tralhão, J.; Botelho, MF; Castro-Sousa, F.. "New therapeutic options for hepatocellular carcinoma: what is the role of Glucose transporter 1?". Paper presented in American College of Surgeons Clinical Congress 2014, 2014.
    Published
  156. Jorge, J.; Cortesão, E.; Gonçalves AC; Pires, A.; Alves, R.; Moucho, C.; Rito, L.; et al. "Gene methylation in myelodysplastic syndrome – A comparative study between bone marrow and peripheral blood". Paper presented in European Society for Medical Oncology Congress 2014, Madrid, 2014.
    Published
  157. Mendes, F.; Schugk, S.; Sales, T.; Abrantes, A.; Gonçalves AC; César, P.; Soares, P.; et al. "Effects of ionizing radiation on H69 cell line". Paper presented in 23rd Biennial Congress of the EUROPEAN ASSOCIATION FOR CANCER RESEARCH, Munich, 2014.
    Published
  158. Fernandes, AI; Ribeiro, AC; Brito, AF; Abrantes, AM; Teixo, R.; Gonçalves AC; Sarmento-Ribeiro, AB; Tralhão, JG; Botelho, MF. "Metabolic radiotherapy with Iodine-131: effects in a human cholangiocarcinoma cell line". Paper presented in Annual Congress of the European Association of Nuclear Medicine, Gothenburg, 2014.
    Published
  159. Gonçalves, TJ; Pires, AS; Encarnação, JC; Casalta, JE; Gonçalves AC; Abrantes, AM; Sarmento-Ribeiro, AB; Botelho, MF. "May butyrate interfere with Warburg effect in colon cancer cells?". Paper presented in Annual Congress of the European Association of Nuclear Medicine, Gothenburg, 2014.
    Published
  160. Gonçalves AC; Alves, R.; Cortesão, E.; Baldeiras, I.; Carda, JP; Barbosa-Ribeiro, A.; Borges, A.; et al. "The interplay between oxidative stress and epigenetic profile in myeloid neoplasias". Paper presented in 19TH Congress of the European Hematology Association, Milan, 2014.
    Published
  161. Cortesão, E.; Jorge, J.; Gonçalves AC; Pires, A.; Alves, R.; Mocho, C.; Rito, L.; et al. "DAPK and TRAIL receptors methylation status in myelodysplastic syndromes patients". Paper presented in 19TH Congress of the European Hematology Association, Milan, 2014.
    Published
  162. Pires, A.; Alves, R.; Jorge, J.; Balça-Silva, J.; Domingues, C.; Gonçalves AC; Sarmento-Ribeiro, AB. "Batimastat, a matrix metalloproteinase inhibitor, as a therapeutic aproach in hematologic neoplasias". Paper presented in 19TH Congress of the European Hematology Association, Milan, 2014.
    Published
  163. Oliveira, L.; Gonçalves AC; Geraldes, C.; Pais, AS; Cortesão, E.; Matafome, P.; Seiça, R.; et al. "The role of adipocytokines in monoclonal gammopathies – A preliminary study". Paper presented in 19TH Congress of the European Hematology Association, Milan, 2014.
    Published
  164. Gonçalves AC; Alves, R.; Cortesão, E.; Freitas-Tavares, P.; Carda, JP; Espadana, AI; Magalhães, E.; et al. "Predisposition to myeloid neoplasias – The role of oxidative stress genes polymorphisms". Paper presented in 19TH Congress of the European Hematology Association, Milan, 2014.
    Published
  165. Santos, K.; Laranjo, M.; Soares, MI; Oliveira, AS; Abrantes, M.; Brito, A.; Gonçalves AC; et al. "Chiral 6,7-bis(hydroxymethyl)-1H,3H-pyrrolo[1,2-c]thiazoles as anticancer agents against breast cancer cell lines". Paper presented in 28ª Reunião - 3º Congresso do CIMAGO, Coimbra, 2014.
    Published
  166. Teixo, R.; Laranjo, M.; Serra, AC; Pineiro, M.; Abrantes, M.; Gonçalves AC; Casalta-Lopes, J.; et al. "Photodynamic therapy in retinoblastoma: cell viability, cell cycle analisys and P53 alterations". Paper presented in 28ª Reunião - 3º Congresso do CIMAGO, Coimbra, 2014.
    Published
  167. Gonçalves AC; Santos, K.; Laranjo, M.; Soares, MI; Oliveira, AS; Abrantes, M.; Brito, A.; et al. "PARP-Inhibitor PJ34 potentiates the anticancer effect of chiral 6,7-bis(hydroxymethyl)-1H,3H-pyrrolo[1,2-c] thiazoles against breast cancer MCF7 and HCC1806 cell lines". Paper presented in 28ª Reunião - 3º Congresso do CIMAGO, Coimbra, 2014.
    Published
  168. Gonçalves AC; Teixo, R.; Laranjo, M.; Serra, AC; Pineiro, M.; Abrantes, M.; Gonçalves, AC; et al. "Effects of photodynamic therapy in cell proliferation and oxidative stress in a retinoblastoma cell line". Paper presented in 28ª Reunião - 3º Congresso do CIMAGO, Coimbra, 2014.
    Published
  169. Mendes, F.; Sales, T.; Schugk, S.; Abrantes, AM; Gonçalves AC; Soares, P.; César, P.; et al. "Cell Death and Cell Cycle Arrest on Non-Hodgkin Lymphoma cell line, the biological response after x-ray irradiation with high doses". Paper presented in 28ª Reunião - 3º Congresso do CIMAGO, Coimbra, 2014.
    Published
  170. Costa, L.; Domingues, C.; Alves, R.; Gonçalves AC; Sarmento-Ribeiro, AB. "Can epigenetic modulation be a new therapeutical approach to diffuse large Bb Cell lymphoma?". Paper presented in 28ª Reunião - 3º Congresso do CIMAGO, Coimbra, 2014.
    Published
  171. Pires, A.; Jorge, J.; Alves, R.; Domingues, C.; Gonçalves AC; Sarmento-Ribeiro, AB. "The bone marrow microenvironment as a therapeutic target in hematologic neoplasias – The role of matrix metalloproteinases". Paper presented in 28ª Reunião - 3º Congresso do CIMAGO, 2014.
    Published
  172. Mendes, F.; Abrantes, AM; Gonçalves AC; Nobre-Góis, I.; Fernandes, P.; Soares, P.; Casalta-Lopes, J.; et al. "The TNF-Alpha dynamics during radiation therapy and T Cells subsets in Diffuse Large B Cell Lymphoma and Non-Small Cell Lung Cancer patients". Paper presented in 28ª Reunião - 3º Congresso do CIMAGO, Coimbra, 2014.
    Published
  173. Alves, R.; Gonçalves AC; Couceiro, P.; Rodrigues-Santos, P.; Freitas-Tavares, P.; Almeida, A.; Sarmento-Ribeiro, AB. "Contribution of ABC transporters in monitoring response in CML patients – Pilot study". Paper presented in 28ª Reunião - 3º Congresso do CIMAGO, Coimbra, 2014.
    Published
  174. Domingues, C.; Ferreira, M.; Pires, C.; Matias, C.; Lourenço, T.; Pires, A.; Jorge, J.; et al. "The role of vismodegib (GDC-0449) in hematological neoplasias treatment". Paper presented in 28ª Reunião - 3º Congresso do CIMAGO, Coimbra, 2014.
    Published
  175. Pais, AS; Gonçalves AC; Geraldes, C.; Cortesão, E.; Sousa, I.; Teixeira, A.; Santos, M.; et al. "Metalloproteinases expression in MGUS and symptomatic multiple myeloma". Paper presented in 28ª Reunião - 3º Congresso do CIMAGO, Coimbra, 2014.
    Published
  176. Geraldes, C.; Gonçalves AC; Alves, R.; Pais, AS; Cortesão, E.; Pereira, MI; Sousa, I.; et al. "P15 and DAPK methylation status in monoclonal gammopathies: Peripheral blood vs. bone marrow study". Paper presented in 28ª Reunião - 3º Congresso do CIMAGO, Coimbra, 2014.
    Published
  177. Cortesão, E.; Jorge, J.; Gonçalves AC; Pires, A.; Alves, R.; Sousa, I.; Moucho, C.; et al. "Gene methylation – The role in myelodyspastic syndrome". Paper presented in 28ª Reunião - 3º Congresso do CIMAGO, Coimbra, 2014.
    Published
  178. Jorge, J.; Cortesão, E.; Gonçalves AC; Pires, A.; Alves, R.; Sousa, I.; Moucho, C.; et al. "Methylation pattern in myelodysplastic syndrome – Comparative study between bone marrow and peripheral blood". Paper presented in 28ª Reunião - 3º Congresso do CIMAGO, Coimbra, 2014.
    Published
  179. Gonçalves AC; Alves, R.; Cortesão, E.; Freitas-Tavares, P.; Carda, JP; Olim, P.; Sousa, P.; et al. "Polymorphisms in oxidative stress genes could influence the predisposition to myeloid neoplasias". Paper presented in 28ª Reunião - 3º Congresso do CIMAGO, Coimbra, 2014.
    Published
  180. Laranjo, M.; Santos, K.; Teixo, R.; Pineiro, M.; Gonçalves AC; Abrantes, M.; Sarmento-Ribeiro, AB; et al. "Photodynamic therapy in non-small cell lung cancer". Paper presented in 28ª Reunião - 3º Congresso do CIMAGO, 2014.
    Published
  181. Brito, AF; Abrantes, AM; Laranjo, M.; Gonçalves AC; Sarmento-Ribeiro, AB; Castro-Sousa, F.; Tralhão, JG; Botelho, MF. "GLUT1 inhibition as a therapeutic approach in hepatocellular carcinoma". Paper presented in 28ª Reunião - 3º Congresso do CIMAGO, Coimbra, 2014.
    Published
  182. Gradiz, R.; Mamede, AC; Abrantes, AM; Guerra, S.; Gonçalves AC; Sarmento-Ribeiro, AB; Botelho, MF; Mota-Pinto, A.. "Docetaxel as a treatment option for pancreatic cancer: Effects of monotherapy and combined therapy with 177LU-DOTA-TATE". Paper presented in 28ª Reunião - 3º Congresso do CIMAGO, Coimbra, 2014.
    Published
  183. Abrantes, AM; Pires, AS; Laranjo, M.; Mamede, AC; Brito, AF; Casalta-Lopes, JE; Gonçalves AC; Sarmento-Ribeiro, AB; Botelho, MF. "Alterations on cell metabolism induced by hypoxia. In vitro study colorectal carcinoma". Paper presented in 28ª Reunião - 3º Congresso do CIMAGO, Coimbra, 2014.
    Published
  184. Pires, AS; Marques, CR; Encarnação, JC; Gonçalves, TJ; Mamede, AC; Casalta-Lopes, JE; Gonçalves AC; et al. "Ascorbic acid and 5-fluorouracil act synergistically against three different colon carcinoma cell lines". Paper presented in 28ª Reunião - 3º Congresso do CIMAGO, Coimbra, 2014.
    Published
  185. Encarnação, JC; Pires, AS; Gonçalves, TJ; Abrantes, AM; Casalta-Lopes, JE; Gonçalves AC; Botelho, MF. "Butyrate and irinotecan: a new therapeutic approach for colon cancer". Paper presented in 28ª Reunião - 3º Congresso do CIMAGO, Coimbra, 2014.
    Published
  186. Ribeiro, AC; Fernandes, AI; Brito, AF; Abrantes, AM; Santos, K.; Gonçalves AC; Sarmento-Ribeiro, AB; Tralhão, JG; Botelho, MF. "Iodine-131, a therapeutic weapon against cholangiocarcinoma?". Paper presented in 28ª Reunião - 3º Congresso do CIMAGO, Coimbra, 2014.
    Published
  187. Brito, AF; Mendes, M.; Ribeiro, M.; Abrantes, AM; Gonçalves AC; Sarmento-Ribeiro, AB; Castro-Sousa, F.; Tralhão, JG; Botelho, MF. "The role of nuclear medicine in the study of multidrug resistance in hepatocelular carcinoma". Paper presented in 27ª Reunião - 2º Congresso do CIMAGO, Coimbra, 2013.
    Published
  188. Gradiz, R.; Abrantes, AM; Mamede, AC; Gonçalves AC; Sarmento-Ribeiro, AB; Botelho, MF; Mota-Pinto, A.. "Treatment of adenocarcinomas with neuroendocrine differentiation with metabolic radiotherapy and chemotherapy". Paper presented in 27ª Reunião - 2º Congresso do CIMAGO, Coimbra, 2013.
    Published
  189. Gonçalves AC; Cortesão, E.; Espadana, AI; Magalhães, E.; Moucho, C.; Rito, L.; Pereira, A.; et al. "Oxidative stress vs Gene methylation – A new risk factor in MDS patients?". Paper presented in 27ª Reunião - 2º Congresso do CIMAGO, Coimbra, 2013.
  190. Geraldes, C.; Gonçalves AC; Alves, R.; Pais, AS; Cortesão, E.; Sousa, I.; Teixeira, A.; Sarmento-Ribeiro, AB. "Epigenetic changes in monoclonal gammopathies – A possible role in the progression of MGUS to multiple myeloma". Paper presented in 27ª Reunião - 2º Congresso do CIMAGO, Coimbra, 2013.
    Published
  191. Pedro, PF; Gonçalves AC; Girão, H.; Mesquita, L.; Sarmento-Ribeiro, AB; Silva, HC. "Interference of proteasome inhibitor MG262 with Wnt and NF-KB pathways in an ovarian cancer cell-line". Paper presented in 27ª Reunião - 2º Congresso do CIMAGO, Coimbra, 2013.
    Published
  192. Pires, AS; Marques, CR; Mamede, AC; Abrantes, AM; Gonçalves AC; Sarmento-Ribeiro, AB; Botelho, MF. "Ascorbic acid and its cytotoxic effect in melanoma: In vitro and in vivo studies". Paper presented in 27ª Reunião - 2º Congresso do CIMAGO, Coimbra, 2013.
    Published
  193. Cortesão, E.; Gonçalves AC; Sousa, I.; Moucho, C.; Carda, J.; Geraldes, C.; Costa e Silva, N.; et al. "Tyrosine kinase FLT 3 and c-KIT receptor expression in patients with myelodysplastic syndromes". Paper presented in 27ª Reunião - 2º Congresso do CIMAGO, Coimbra, 2013.
    Published
  194. Ferreira, M.; Guarino, P.; Domingues, C.; Leite, J.; Alves, R.; Gonçalves AC; Sarmento-Ribeiro, AC. "WNT/B-CATENIN, NOTCH and HEDGEHOG pathways – Possible new targets to all therapy". Paper presented in 27ª Reunião - 2º Congresso do CIMAGO, Coimbra, 2013.
    Published
  195. Mendes, F.; Silva, R.; Abrantes, AM; Gonçalves AC; Laranjo, M.; Casalta, J.; César, P.; et al. "Evaluation of the effects of X radiation in Lymphoma and Lung cancer cell lines – The interplay between oxidative stress and P53 levels". Paper presented in 27ª Reunião - 2º Congresso do CIMAGO, Coimbra, 2013.
    Published
  196. Pais, AS; Gonçalves AC; Geraldes, C.; Cortesão, E.; Sousa, I.; Alves, V.; Santos, M.; et al. "Do metalloproteinases play a role in the pathogenesis and progression from MGUS to MM?". Paper presented in 27ª Reunião - 2º Congresso do CIMAGO, Coimbra, 2013.
    Published
  197. Domingues, C.; Leite, J.; Ferreira, M.; Guarino, P.; Alves, R.; Coucelo, M.; Ribeiro, L.; et al. "Effects of TRAIL and survivin inhibitors in acute lymphoblastic leukemia treatment – An in vitro suty". Paper presented in 27ª Reunião - 2º Congresso do CIMAGO, Coimbra, 2013.
    Published
  198. Leite, J.; Ferreira, M.; Guarino, P.; Domingues, C.; Alves, R.; Gonçalves AC; Sarmento-Ribeiro, AB. "Hydrogen peroxide and menadione alter DNA methylation status in acute lymphoblastic leukemia cells in vitro". Paper presented in 27ª Reunião - 2º Congresso do CIMAGO, Coimbra, 2013.
    Published
  199. Mamede, AC; Tavares-Silva, E.; Abrantes, AM; Botas, F.; Pires, AS; Gonçalves AC; Sarmento-Ribeiro, AB; et al. "Development of an orthotopic model of prostate cancer: A step closer to the real in vivo model". Paper presented in 27ª Reunião - 2º Congresso do CIMAGO, Coimbra, 2013.
    Published
  200. Brito, AF; Abrantes, AM; Ribeiro, M.; Gonçalves AC; Sarmento-Ribeiro, AB; Castro-Sousa, F.; Tralhão, JG; Botelho, MF. "New perspectives on hepatocellular carcinoma treatment: The role of gossypol". Paper presented in 27ª Reunião - 2º Congresso do CIMAGO, Coimbra, 2013.
    Published
  201. Brito, AF; Ribeiro, M.; Abrantes, AM; Gonçalves AC; Sarmento-Ribeiro, AB; Castro-Sousa, F.; Tralhão, JG; Botelho, MF. "Quercetin: An option in hepatocellular carcinoma therapy?". Paper presented in 27ª Reunião - 2º Congresso do CIMAGO, Coimbra, 2013.
    Published
  202. Pereira, A.; Silva, D.; Matafome, P.; Gonçalves AC; Seiça, R.; Sarmento-Ribeiro, AB; Nascimento-Costa, AB. "The role of adipocitokines in colorectal cancer development and progression – A preliminary study". Paper presented in 27ª Reunião - 2º Congresso do CIMAGO, Coimbra, 2013.
    Published
  203. Guarino, P.; Alves, R.; Domingues, C.; Leite, J.; Ferreira, M.; Gonçalves AC; Pais, C.; et al. "Genetic cancer susceptibility in down syndrome – A preliminary study". Paper presented in 27ª Reunião - 2º Congresso do CIMAGO, Coimbra, 2013.
    Published
  204. Alves, R.; Gonçalves AC; Freitas-Tavares, P.; Couceiro, P.; Rodrigues-Santos, P.; Sarmento-Ribeiro, AB. "ABC Expression As Additionally Marker To Monitoring Response In CML - A Preliminary Study". Paper presented in American Society of Hematology (ASH) 55th Annual Meeting, New Orleans, 2013.
    Published
  205. Gonçalves AC; Alves, R.; Freitas-Tavres, P.; Teixeira, A.; Mota-Vieira, L.; Nascimento-Costa, JM; Sarmento-Ribeiro, AB. "Can Polymorphisms In Oxidative Stress Related Genes Be a Risk Factor For CML?". Paper presented in American Society of Hematology (ASH) 55th Annual Meeting, New Orleans, 2013.
    Published
  206. Brito, AF; Mendes, M.; Ribeiro, M.; Abrantes, AM; Gonçalves AC; Sarmento-Ribeiro, AB; Castro-Sousa, F.; Tralhão, JG; Botelho, MF. "18F-FDG an alternative to 99mTC-MIBI in the study of multidrug resistance in hepatocellular carcinoma?". Paper presented in Annual Congress of the European Association of Nuclear Medicine, Lyon, 2013.
    Published
  207. Ribeiro, M.; Brito, AF; Abrantes, AM; Gonçalves AC; Sarmento-Ribeiro, AB; Castro-Sousa, F.; Tralhão, JG; Botelho, MF. "Quercetin: an option in primary liver tumors therapy?". Paper presented in Annual Congress of the European Association of Nuclear Medicine, Lyon, 2013.
    Published
  208. Ferreira, S.; Abrantes, AM; Brito, AF; Laranjo, M.; Gonçalves AC; Sarmento-Ribeiro, AB; Metello, L.; et al. "Radiolabeled polyethyleneiminomethyl phosphonic acid as a molecule with potential for diagnosis and therapy. Comparative study on models of bladder cancer and osteossarcoma". Paper presented in Annual Congress of the European Association Of Nuclear Medicine, Lyon, 2013.
    Published
  209. Abrantes, A.; Pires, AS; Laranjo, M.; Mamede, AC; Brito, AF; Casalta-Lopes, J.; Gonçalves AC; Sarmento-Ribeiro, AB; Botelho, MF. "Hypoxia induced alterations on cell metabolism - an in vitro study in three different colorectal carcinoma cell lines". Paper presented in European Cancer Congress 2013, Amsterdam, 2013.
    Published
  210. Gradiz, R.; Mamede, AC; Abrantes, AM; Casalta-Lopes, JE; Gonçalves AC; Sarmento-Ribeiro, AB; Botelho, MF; Mota-Pinto, A.. "Chemotherapy for adenocarcinomas with neuroendocrine differentiation: A study in two pancreatic cancer cell lines with different somatostatin receptors expression". Paper presented in European Cancer Congress 2013, Amsterdam, 2013.
    Published
  211. Brito, AF; Abrantes, AM; Ribeiro, M.; Casalta-Lops, JE; Gonçalves AC; Sarmento-Ribeiro, AB; Tralhão, JG; Botelho, MF. "Gossypol: An option in cholangiocarcinoma therapy?". Paper presented in European Cancer Congress 2013, Amsterdam, 2013.
    Published
  212. Brito, AF; Ribeiro, M.; Abrantes, AM; Casalta-Lopes, JE; Gonçalves AC; Sarmento-Ribeiro, AB; Tralhão, JG; Botelho, MF. "New options in primary liver tumors: The role of quercetin". Paper presented in European Cancer Congress 2013, Amsterdam, 2013.
    Published
  213. Mendes, F.; Silva, R.; Abrantes, AM; Gonçalves AC; Laranjo, M.; César, P.; Casalta-Lopes, JE; et al. "X radiation effects on small cell lung cancer and non-small lung cancer - an in vitro study". Paper presented in European Cancer Congress 2013, Amsterdam, 2013.
    Published
  214. Brito, AF; Mendes, M.; Ribeiro, M.; Abrantes, AM; Casalta-Lopes, JE; Gonçalves AC; Sarmento-Ribeiro, AB; Tralhão, JG; Botelho, MF. "Nuclear medicine in the study of multidrug resistance in hepatocellular carcinoma: Studies with 18F-FDG and 99mTC-MIBI". Paper presented in European Cancer Congress 2013, Amsterdam, 2013.
    Published
  215. Marques, CR; Pires, AS; Encarnação, JC; Gonçalves, TJ; Mamede, AC; Casalta-Lopes, JE; Gonçalves AC; et al. "Is there a synergistic effect between ascorbic acid and conventional chemotherapy in the treatment of colorectal carcinoma?". Paper presented in European Cancer Congress 2013, Amsterdam, 2013.
    Published
  216. Priolli, DG; Martinez, NP; Abrantes, AM; Gonçalves AC; Laranjo, M.; Lopes, CO; Pereira, JA; et al. "From monoclonal tumor cell arises an identical colon adenocarcinoma?". Paper presented in European Cancer Congress 2013, Amsterdam, 2013.
    Published
  217. Alves, R.; Ferreira, M.; Guarino, P.; Domingues, C.; Leite, J.; Gonçalves AC; Sarmento-Ribeiro, AB. "Vismodegib – An hedgehog pathway inhibitor induces cell death in an all cell line". Paper presented in 18th Congress of the European Hematology Association, Stockholm, 2013.
    Published
  218. Gonçalves AC; Leite, J.; Ferreira, M.; Guarino, P.; Domingues, C.; Alves, R.; Sarmento-Ribeiro, AB. "Oxidative stress influence hydroxymethylation status in acute lymphoblastic leukemia cells in vitro". Paper presented in 18th Congress of the European Hematology Association, Stockholm, 2013.
    Published
  219. Geraldes, C.; Gonçalves AC; Alves, R.; Pais, A.; Cortesão, E.; Pereira, M.; Sousa, I.; et al. "P15 and DAPK methylation in multiple myeloma and MGUS: Comparison between bone marrow and peripheral blood". Paper presented in 18th Congress of the European Hematology Association, Stockholm, 2013.
    Published
  220. Domingues, C.; Leite, J.; Ferreira, M.; Guarino, P.; Alves, R.; Coucelo, M.; Ribeiro, L.; et al. "RHTRAIL and survivin downregulators as new therapeutic approach in acute lymphoblastic leukemia". Paper presented in 18th Congress of the European Hematology Association, Stockholm, 2013.
    Published
  221. Geraldes, C.; Gonçalves AC; Alves, R.; Pais, AS; Cortesão, E.; Sousa, I.; Teixeira, A.; Nascimento-Costa, JM; Sarmento-Ribeiro, AB. "Is P16 and Dapk Genes Hypermetilation Relevant in the Progression of MGUS to Multiple Myeloma?". Paper presented in 14th International Myeloma Workshop, Kyoto, 2013.
    Published
  222. Mendes, M.; Brito, A.; Abrantes, A.; Veríssimo, F.; Gonçalves AC; Sarmento-Ribeiro, AB; Tralhão, JG; Botelho, M.. "18F-FDG uptake in hepatocellular carcinoma cell lines: correlation with multidrug resistance proteins expression". Paper presented in ESMO 2012 CONGRESS, Vienna, 2012.
    Published
  223. Gomes, A.; Abrantes, A.; Brito, A.; Laranjo, M.; Casalta-Lopes, J.; Gonçalves AC; Sarmento-Ribeiro, AB; Botelho, M.; Tralhão, J.. "The importance of protein P53 on iodide-131 treatment efficacy in hepatocellular carcinoma". Paper presented in ESMO 2012 CONGRESS, Vienna, 2012.
    Published
  224. Silva, V.; Pires, A.; Abrantes, A.; Brito, A.; Gonçalves AC; Sarmento-Ribeiro, AB; Botelho, M.. "Effect of a-tocoferil succinate in two different cell lines of colorectal adenocarcinoma". Paper presented in ESMO 2012 CONGRESS, Vienna, 2012.
    Published
  225. Pires, A.; Mamede, A.; Silva, V.; Abrantes, A.; Brito, A.; Gonçalves AC; Sarmento-Ribeiro, AB; Botelho, MF. "Ascorbic acid and its therapeutic potential against colorectal adenocarcinoma". Paper presented in ESMO 2012 CONGRESS, Vienna, 2012.
    Published
  226. Mendes, M.; Brito, AF; Abrantes, AM; Veríssimo, F.; Gonçalves AC; Sarmento-Ribeiro, AB; Castro-Sousa, F.; Tralhão, JG; Botelho, MF. "18F-FDG versus 99mtc-MIBI in study of multidrug resistance in hepatocellular carcinoma". Paper presented in Annual Congress of the European Association of Nuclear Medicine, Milan, 2012.
    Published
  227. Gomes, AR; Abrantes, AM; Laranjo, M.; Casalta-Lopes, JE; Gonçalves AC; Sarmento-Ribeiro, AB; Castro-Sousa, F.; Tralhão, JG; Botelho, MF. "Iodide-131: efficacy of treatment in hepatocellular carcinoma and the influence of p53 protein". Paper presented in Annual Congress of the European Association of Nuclear Medicine, Milan, 2012.
    Published
  228. Olim, P.; Sousa, P.; Gonçalves AC; Mesquita, L.; Breda Coimbra, H.; Moucho, C.; Cortesão, E.; et al. "Prognostic significance of FLT3 and NPM1 mutations in myeloid malignancies". Paper presented in 17th Congress of the European Hematology Association (EHA), Amsterdam, 2012.
    Published
  229. Mendes, J.; Ribeiro, A.; Gonçalves AC; Alves, R.; Alves, V.; Sarmento-Ribeiro, AB. "Focus on intracellular signaling - New targeted therapeutic approaches in diffuse large b-cells lymphoma". Paper presented in 17th Congress of the European Hematology Association (EHA), Amsterdam, 2012.
    Published
  230. Geraldes, C.; Gonçalves AC; Cortesão, E.; Teixeira, A.; Nascimento-Costa, J.; Sarmento-Ribeiro, AB. "Multidrug resistance 1 (MDR1) gene and ABC family proteins (MDR1 and MRP1) in monclonal gammopathies (multiple myeloma and monoclonal gammopathy of uncertain significance)". Paper presented in 17th Congress of the European Hematology Association (EHA), Amsterdam, 2012.
    Published
  231. Pais, AS; Gonçalves AC; Geraldes, C.; Cortesão, E.; Ferreira, V.; Alves, V.; Sousa, I.; et al. "Evaluation of metalloproteinases expression levels in MGUS and MM patients". Paper presented in 17th Congress of the European Hematology Association (EHA), Amsterdam, 2012.
    Published
  232. Alves, R.; Fonseca, R.; Gonçalves AC; Alves, V.; Sarmento-Ribeiro, AB. "Targeting the RAS/MAPK and PI3K/MTOR signaling pathways: A new approach in sensitive and resistant CML cell lines?". Paper presented in 17th Congress of the European Hematology Association (EHA), Amsterdam, 2012.
    Published
  233. Gonçalves AC; Cortesão, E.; Espadana, A.; Magalhães, E.; Moucho, C.; Rito, L.; Pereira, A.; et al. "Oxidative stress can influence gene methylation status in MDS patients". Paper presented in 17th Congress of the European Hematology Association (EHA), Amsterdam, 2012.
    Published
  234. Cortesão, E.; Gonçalves AC; Sousa, I.; Moucho, C.; Rito, L.; Magalhães, E.; Carda, JP.; et al. "Tyrosine Kinase FLT3 and C-KIT Receptor Expression in Patients with Myelodysplastic Syndromes – A Preliminary Study". Paper presented in 54th American Society of Hematology Annual Meeting, Atlanta, 2012.
    Published
  235. Laranjo, M.; Serra, AC; Abrantes, AM; Pineiro, M.; Gonçalves AC; Oliveiros, B.; Sarmento-Ribeiro, AB; Rocha-Gonsalves, AM; Botelho, MF. "TBr4 and BBr2 as Sensitizers for Photodynamic Therapy Against Human Colorectal Adenocarcinoma - in Vitro Studies". Paper presented in 22nd Biennial Congress of the European Association for Cancer Research, Barcelona, 2012.
    Published
  236. Gomes, AR; Abrantes, AM; Laranjo, M.; Casalta-Lopes, JE; Gonçalves AC; Sarmento-Ribeiro, AB; Tralhão, JG; Botelho, MF. "The Influence of p53 in Iodide-131 Treatment Efficacy in Hepatocellular Carcinoma". Paper presented in 22nd Biennial Congress of the European Association for Cancer Research, Barcelona, 2012.
    Published
  237. Pires, AS; Mamede, AC; Silva, VS; Abrantes, AM; Gonçalves AC; Sarmento-Ribeiro, AB; Botelho, MF. "Ascorbic Acid Effect in Two Different Cell Lines of Colorectal Adenocarcinoma - in Vitro and in Vivo Studies". Paper presented in 22nd Biennial Congress of the European Association for Cancer Research, Barcelona, 2012.
    Published
  238. Mendes, M.; Brito, AF; Abrantes, AM; Veríssimo, F.; Gonçalves AC; Sarmento-Ribeiro, AB; Tralhão, JG; Botelho, MF. "Multidrug Resistance in Hepatocellular Carcinoma - Correlation With 18F-FDG Uptake (Preliminary Results)". Paper presented in 22nd Biennial Congress of the European Association for Cancer Research, Barcelona, 2012.
    Published
  239. Brito, AF; Abrantes, AM; Costa, CP; Matos, CC; Mamede, AC; Gonçalves AC; Rodrigues, MC; et al. "18F-FDG uptake in hepatocellular carcinoma: correlation with GLUT1 and p53 expression". Paper presented in Annual Congress of the European Association of Nuclear Medicine, Birmingham, 2011.
    Published
  240. Valente, S.; Abrantes, AM; Gonçalves AC; Mamede, AC; Sarmento-Ribeiro, AB; Botelho, MF. "99mTc-Hynic-Annexin-V: cellular uptake of apoptotic cells induced by TRAIL and in vivo imaging of apoptosis in colon tumour". Paper presented in Annual Congress of the European Association of Nuclear Medicine, Birmingham, 2011.
    Published
  241. Alves, R.; Fonseca, R.; Gonçalves AC; Alves, V.; Abrantes, AM; Botelho, F.; Sarmento-Ribeiro, AB. "Drug Transporters in Imatinib Resistance: A New Therapeutic Targeted Approach In CML". Paper presented in American Society of Hematology 53rd Annual Meeting, San Diego, 2011.
    Published
  242. Geraldes, C.; Gonçalves AC; Alves, V.; Teixeira, A.; Sousa, I.; Santos Rosa, M.; Nascimento-Costa, JM; Sarmento-Ribeiro, AB. "Evaluation of apoptotic markers in multiple myeloma and monoclonal gammopathy of undetermined significance". Paper presented in 16th Congress of European Hematology Association, London, 2011.
    Published
  243. Brito, AF; Abrantes, AM; Pinto-Costa, C.; Mamede, AC; Matos, C.; Rodrigues, MC; Gonçalves AC; et al. "GLUT1 expression in hepatocellular carcinoma: Correlation with 18F-FDG uptake". Paper presented in 46th annual meeting of the European Association for the Study of the Liver, Berlin, 2011.
    Published
  244. Oliveira, R.; Abrantes, AM; Gonçalves AC; Rio, J.; Sarmento-Ribeiro, AB; Carreira, I.; Botelho, MF. "Ionizing radiation: a comparative study in cell lines.". Paper presented in Annual Congress of the European Association of Nuclear Medicine, Vienna, 2010.
    Published
  245. Tralhão, JG; Abrantes, AM; Gonçalves AC; Tavares, S.; Mamede, AC; Brito, AF; Cardoso, D.; et al. "Impact of splenic artery ligation after major hepatectomy on hepatcellular function or viability". Paper presented in Annual Congress of the European Association of Nuclear Medicine, Vienna, 2010.
    Published
  246. Sampaio, A.; Mendes, L.; Gonçalves AC; Abrantes, AM; Sarmento-Ribeiro, AB; Botelho, F.; Oliveira, P.; et al. "Malignant transformation of human bronchial epithelial cells (BEAS-2B) by Cr(VI) is associated with altered mitochondria and bioenergetic phenotype". Paper presented in 35th FEBS Congress, Gothenburg, 2010.
    Published
  247. Casalta-Lopes, J.; Abrantes, AM; Rio, J.; Laranjo, M.; Oliveiros, B.; Gonçalves AC; Sarmento-Ribeiro, AB; Botelho, MF. "MDR modulation in colorectal adenocarcinoma cell lines: kinetic studies using 99mTc-sestamibi". Paper presented in 16th International Charles Heidelberger Symposium on Cancer Research, Coimbra, 2010.
    Published
  248. Carvalho, JA; Cortesão, E.; Branco, JD; Gonçalves AC; Neves, S.; Carvalho, F.; Ribeiro, A.; et al. "Histone deacetylation - a new epigenetic target in cancer". Paper presented in 16th International Charles Heidelberger Symposium on Cancer Research, Coimbra, 2010.
    Published
  249. Gonçalves AC; Oliveira, A.; Moreira, D.; Neves, S.; Alves, V.; Silva, T.; Mesquita, L.; et al. "New targeted therapies in myelodysplastic syndrome: the role of farnesyltransferase and proteasome inhibitors". Paper presented in 16th International Charles Heidelberger Symposium on Cancer Research, Coimbra, 2010.
    Published
  250. Pais, AS; Gonçalves AC; Geraldes, C.; Nascimento-Costa, JM; Sarmento-Ribeiro, AB. "Metalloproteinase inhibitors as a potential therapeutic approach in multiple myeloma: a preliminary study". Paper presented in 16th International Charles Heidelberger Symposium on Cancer Research, Coimbra, 2010.
    Published
  251. Carvalho, F.; Coelho, AS; Domingues, C.; Carvalho, JA; Ribeiro, A.; Santos, RM; Gonçalves AC; et al. "Recombinant trail: a synergistic effect in myeloid leukemias". Paper presented in 16th International Charles Heidelberger Symposium on Cancer Research, Coimbra, 2010.
    Published
  252. Barbosa Ribeiro, A.; Ferreira, AL; Gonçalves AC; Neves, S.; Araújo, AM; Carvalho, F.; Carvalho, J.; et al. "Delocalized lipophilic cations as a new therapeutic approach in cancer". Paper presented in 16th International Charles Heidelberger Symposium on Cancer Research, Coimbra, 2010.
    Published
  253. Abrantes, AM; Martins, M.; Gonçalves AC; Rodrigues, MC; Mamede, AC; Tavares, SD; Lima, JM; et al. "GLUT expression and 18F-FDG uptake in breast cancer cell lines". Paper presented in 16th International Charles Heidelberger Symposium on Cancer Research, Coimbra, 2010.
    Published
  254. Silva, JB; Neves, SS; Gonçalves AC; Marques, M.; Mesquita, L.; Botelho, F.; Sarmento-Ribeiro, AB; Silva, HC. "Evaluation of the role of mir-34b in modulation of radioresistance in non-small cell lung cancer". Paper presented in 16th International Charles Heidelberger Symposium on Cancer Research, Coimbra, 2010.
    Published
  255. Sampaio, A.; Mendes, L.; Rodrigues, CF; Gonçalves AC; Abrantes, M.; Sarmento-Ribeiro, AB; Botelho, MF; et al. "Cr(VI)-induced malignant transformation of a bronchial epithelial cell line association with altered mitochondria and bioenergetic phenotypes". Paper presented in 16th International Charles Heidelberger Symposium on Cancer Research, Coimbra, 2010.
    Published
  256. Batista, J.; Neves, SS; Gonçalves AC; Alves, V.; Sarmento-Ribeiro, AB; Dourado, M.. "The role of CD26 and CD40 expression in therapeutic response - experimental study in oral cancer lines". Paper presented in 16th International Charles Heidelberger Symposium on Cancer Research, Coimbra, 2010.
    Published
  257. Santos, R.; Gonçalves AC; Alves, V.; Figueirinha, A.; Lopes, MC; Batista, MT; Sarmento-Ribeiro, AB. "Therapeutic effect evaluation of monomeric and polymeric flavonoids, and phenolic acids in acute promyelocytic leukemia". Paper presented in 15th Congress of European Hematology Association, Barcelona, 2010.
    Published
  258. Carvalho, JA; Costa, C.; Carvalho, F.; Ribeiro, A.; Gonçalves AC; Alves, V.; Dourado, M.; Sarmento-Ribeiro, AB. "The role of epigenetic modulators as a therapeutic approach in lymphoid leukemias - A comparative study". Paper presented in 15th Congress of European Hematology Association, Barcelona, 2010.
    Published
  259. Carvalho, F.; Coelho, AS; Domingues, C.; Carvalho, JA; Ribeiro, A.; Costa, S.; Gonçalves AC; et al. "Evaluation of the therapeutic potential of a recombinant trail in leukemia - A study in cell lines in culture". Paper presented in 15th Congress of European Hematology Association, Barcelona, 2010.
    Published
  260. Gonçalves AC; Cortesão, E.; Espadana, AI; Rito, L.; Magalhães, E.; Lobão, MJ; Pereira, A.; et al. "MNSOD ALA(16)VAL polymorfism as a risk marker for myelodysplastic syndrome?". Paper presented in 15th Congress of European Hematology Association, Barcelona, 2010.
    Published
  261. Priolli, D.; Abrantes, AM; Dourado, M.; Sarmento, AB; Carvalho, L.; Gonçalves AC; Neves, S.; Botelho, MF. "New animal model in colorectal cancer". Paper presented in 21st Meeting of the European Association for Cancer Research, Oslo, 2010.
    Published
  262. Silva, J.; Neves, SS; Gonçalves AC; Abrantes, M.; Mesquita, L.; Botelho, F.; Sarmento-Ribeiro, AB; Silva, HC. "Evaluation of the role of mir-34b in modulation of radioresistance in non-small-cell lung cancer". Paper presented in 21st Meeting of the European Association for Cancer Research, Oslo, 2010.
    Published
  263. Casalta-Lopes, J.; Abrantes, AM; Rio, J.; Laranjo, M.; Oliveiros, B.; Gonçalves AC; Sarmento-Ribeiro, AB; Botelho, MF. "MDR modulation in adenocarcinoma cell lines: nuclear medicine as an important approach". Paper presented in 21st Meeting of the European Association for Cancer Research, Oslo, 2010.
    Published
  264. Abrantes, AM; Martins, M.; Rodrigues, MC; Tavares, S.; Mamede, C.; Gonçalves AC; Oliveiros, B.; et al. "Does GLUTs expression influence 18F-FDG uptake? Study in breast cancer cell lines". Paper presented in 21st Meeting of the European Association for Cancer Research, Oslo, 2010.
    Published
  265. Cortesão, EN; Gonçalves AC; Sousa, MI; Moucho, C.; Rito, L.; Magalhães, E.; Espadana, AI; et al. "Evaluation of apoptotic molecular markers and gene methylation status in patients with myelodysplastic syndrome". Paper presented in 14th Congress of the European Hematology Association, Berlin, 2009.
    Published
  266. Gonçalves AC; Alves, V.; Silva, T.; Sarmento-Ribeiro, AB. "Vitamin C show antitumor activity against myelodysplastic syndrome cells". Paper presented in 14th Congress of the European Hematology Association, Berlin, 2009.
    Published
  267. Gonçalves AC; Cortesão, E.; Alves, V.; Espadana, AI; Rito, L.; Magalhães, E.; Pereira, S.; et al. "CD34 cells are under oxidative stress - Possible implication in MDS pathogenesis". Paper presented in 14th Congress of the European Hematology Association, Berlin, 2009.
    Published
  268. Oliveira, R.; Abrantes, AM; Rio, J.; Gonçalves AC; Pinto, M.; Sarmento-Ribeiro, AB; Carreira, IM; Botelho, MF. "Cellular effects of 140 keV ionizing radiation". Paper presented in Annual Congress of the European Association of Nuclear Medicine, Barcelona, 2009.
    Published
  269. Metello, L.; Cunha, L.; Lourenço, L.; Abrantes, A.; Laranjo, M.; Gonçalves AC; Sarmento-Ribeiro, AB; Dormehl, IC; Botelho, MF. "Uptake kinetic studies of 99mTcO-4 and 188ReO-4 on CRL-1472 and MNNG-HOS cell lines". Paper presented in Annual Congress of the European Association of Nuclear Medicine, Barcelona, 2009.
    Published
  270. Casalta-Lopes, J.; Abrantes, AM; Rio, J.; Laranjo, M.; Oliveiros, B.; Gonçalves AC; Sarmento-Ribeiro, AB; Botelho, MF. "MDR and MDR reversal kinetics in human adenocarcinoma cell lines". Paper presented in Annual Congress of the European Association of Nuclear Medicine, Barcelona, 2009.
    Published
  271. Tralhão, JG; Abrantes, AM; Gonçalves AC; Oliveiros, B.; Cardoso, D.; Laranjo, M.; Carvalho, C.; et al. "Study of hepatocellular function in a murine model with normal liver after hepatic artery selective clamping". Paper presented in Annual Congress of the European Association of Nuclear Medicine, Barcelona, 2009.
    Published
  272. Tralhão, JG; Abrantes, AM; Gonçalves AC; Oliveiros, B.; Carvalho, C.; Portela, I.; Laranjo, M.; et al. "Impact of portal vein clamping in hepatocellular function in the murine model with normal liver". Paper presented in Annual Congress of the European Association of Nuclear Medicine, Barcelona, 2009.
    Published
  273. Gonçalves AC; Cortesão, E.; Sousa, MI; Moucho, C.; Rito, L.; Magalhães, E.; Espadana, AI; et al. "Evaluation of Apoptotic Molecular Markers in Myelodysplastic Syndrome Patients". Paper presented in American Society of Hematology 50th Annual Meeting, San Francisco, 2008.
    Published
  274. Cortesão, E.; Gonçalves AC; Sousa, MI; Moucho, C.; Pereira, MA; Nascimento-Costa, J.; Sarmento, AB. "Evaluation of gene methylation status in patients with myelodysplastic syndrome: new prognostic markers?". Paper presented in 13th Congress of European Hematology Association, Copenhagen, 2008.
    Published
  275. Sarmento-Ribeiro, AB; Costa, C.; Carmo, JF; Oliveira, PM; Gonçalves AC; Oliveira, A.; Moreira, D.; et al. "Epigenetic modulation - A new therapeutic approach to lymphoid malignancies". Paper presented in 13th Congress of European Hematology Association, Copenhagen, 2008.
    Published
  276. Casalta-Lopes, JE; Abrantes, AM; Laranjo, M.; Gonçalves AC; Sarmento-Ribeiro, AB; Botelho, MF. "MIBI as MDR probe: in vitro studies in two human colorectal adenocarcinoma cell lines". Paper presented in Annual Congress of the European Association of Nuclear Medicine, Munich, 2008.
    Published
  277. Tralhão, JG; Abrantes, AM; Gonçalves AC; Laranjo, M.; Portela, I.; Martins, C.; Castro-Sousa, L.; et al. "Impact of portal triad clamping (Pringle Maneuver) on hepatic function in a murine model of hepatocellular carcinoma". Paper presented in Annual Congress of the European Association of Nuclear Medicine, Munich, 2008.
    Published
  278. Pires, S.; Abrantes, AM; Laranjo, M.; Serra, E.; Gonçalves AC; Crespo, P.; Rocha-Gonsalves, AM; Sarmento-Ribeiro, AB; Botelho, MF. "Ascorbic acid and its potentiality as image agent and anticancer drug". Paper presented in Annual Congress of the European Association of Nuclear Medicine, Munich, 2008.
    Published
  279. Sarmento-Ribeiro, AB; Costa, C.; Casalta, JE; Andrade, C.; Oliveira, A.; Moreira, D.; Gonçalves AC; et al. "Farnesyltransferase inhibitors as a new therapeutic approach in acute lymphoblastic leukemia". Paper presented in 12th Congress of the European Hematology Association, Vienna, 2007.
    Published
  280. Sarmento-Ribeiro, AB; Dourado, M.; Gonçalves AC; Cortesão, E.; Geraldes, C.; Rito, L.; Sousa, I.; et al. "Effects of bortezomib in apoptosis in B-CLL cells independently of prior therapy - Characterization of biochemical mechanisms associated with the response". Paper presented in 11th Congress of the European Hematology Association, Amsterdam, 2006.
    Published
  281. Dourado, M.; Gonçalves AC; Emília, E.; Sousa, I.; Paiva, A.; Pereira, A.; Guedes, F.; Teixeira, A.; Sarmento-Ribeiro, AB. "TRAIL receptors in B-CLL patients independently of ZAP 70 expression". Paper presented in 11th Congress of the European Hematology Association, Amsterdam, 2006.
    Published
  282. Gonçalves AC; Oliveira, A.; Moreira, D.; Costa, C.; Lopes, JE; Andrade, CJ; Silva, T.; et al. "Potential therapeutic approach of recombinant TRAIL in CML in blast crisis". Paper presented in 11th Congress of the European Hematology Association, Amsterdam, 2006.
    Published
  283. Sarmento-Ribeiro, AB; Gonçalves AC; Abrantes, AM; Breda, H.; Botelho, MF. "Effect of the PKC-Beta Inhibitor, Enzastaurin, in Acute Leukemia - A Preliminary Study in Cell Culture.". Paper presented in 48th American Society of Hematology Annual Meeting, 2006.
    Published
  284. Geraldes, C.; Gonçalves AC; Santos, P.; Tavares, P.; Teixeira, A.. "BCR-ABL Fusion Gene and BCR-ABL Transcript - Correlation with Response to Therapy in Chronic Myeloid Leukaemia.". Paper presented in American Society of Hematology 47th Annual Meeting, Atlanta, 2005.
    Published
  285. Sarmento-Ribeiro, AB; Dourado, M.; Gonçalves AC; Geraldes, C.; Cortesão, E.; Rito, L.; Sousa, I.; et al. "Bortezomib - A Potential Therapeutic Approach in B Chronic Lymphocytic Leukaemia.". Paper presented in American Society of Hematology 47th Annual Meeting, Atlanta, 2005.
    Published
Conference poster
  1. Costa, MI; Lapa, B; Jorge, J; Alves, R; Sarmento-RIbeiro, AB; Gonçalves AC. "Zinc in the modulation of the DNA damage response: Preventive, genotoxic, and cytotoxic roles in acute myeloid leukemia". Paper presented in CIMAGO Congress, 2024.
  2. Alves, R; Gomes, R; Furtado, S; Jorge, J; Lapa, B; Costa, MI; Gonçalves AC; Sarmento-Ribeiro AB. "Telaglenastat, a glutaminase inhibithor, as a potential therapeutic target in chronic myeloid leukemia". Paper presented in CIMAGO Congress, 2024.
  3. Gomes, AR; Costa, S; Abrantes, AM; Gonçalves AC; Alves, R; Sarmento-RIbeiro, AB; Botelho, MF; et al. "Steroidal oximes as a potential new therapeutic for different types of cancer". Paper presented in CIMAGO Congress, 2024.
  4. Marques, I; Figueiredo, D; Pires, AS; Alves, R; Gonçalves AC; Simões, P; Botelho, MF; Abrantes, AM. "Cellular response of human skin keratinocytes to external beam radiotherapy". Paper presented in CIMAGO Congress, 2024.
  5. Serambeque, B; Oliveira, G; Maia, G; Silva, M; Gonçalves AC; Alves, R; Sarmento-RIbeiro, AB; et al. "Evaluation of the effect of sublethal photodynamic therapy on endometrial cancer". Paper presented in CIMAGO Congress, 2024.
  6. Marto, CM; Laranjo, M; Gonçalves AC; Paula, A; Jorge, J; Sarmento-Ribeiro, AB; Marques-Ferreira, M; et al. "In vitro characterization of dedifferentiated gingival fibro-blasts". Paper presented in IV Metabolism, Ageing & Disease (MAD) Meeting, 2024.
  7. Serambeque, B; Correia-Barros, G; Mestre, C; Silva, M; Pineiro, M; Pereira, N; Gonçalves AC; et al. "Photodynamic therapy based on ring-fused chlorins: a promising strategy to eliminate endometrial cancer stem cells?". Paper presented in IV Metabolism, Ageing & Disease (MAD) Meeting, 2024.
  8. Gomes, R; Jorge., J; Lapa, B; Costa, MI; Gonçalves AC; Alves, R; Sarmento-Ribeiro, AB. "Inibição da glutaminólise com telaglenastat na leucemia mieloide crónica resistente ao imatinib: Estudo in vitro". Paper presented in 31ª Sabatina de Hematologia, 2023.
  9. Lapa, B; Costa, MI; Figueiredo, D; Jorge, J; Alves, R; Monteiro, AR; Silva, MR; et al. "O potencial terapêutico do AZD-7648, um inibidor da DNA-PK, na leucemia mieloblástica aguda – Um estudo in vitro". Paper presented in 31ª Sabatina de Hematologia, 2023.
  10. Costa, MI; Lapa, B; Jorge, J; Alves, R; Sarmento-Ribeiro AB; Gonçalves AC. "O zinco na modulação da resposta à lesão do DNA: Efeito preventivo, genotóxicos e citotóxico na leucemia mieloblástica aguda". Paper presented in 31ª Sabatina de Hematologia, 2023.
  11. Ventura, F; Alves, R; Jorge, J; Marques, G; Coucelo, M; Diamond, J; Freitas-Tavares, P; et al. "Influência das variantes genéticas do NFE2L2 na resposta à terapêutica na leucemia mielóide crónica". Paper presented in 31ª Sabatina de Hematologia, 2023.
  12. Jorge, J; Oliveira, I; Alves, R; Lapa, B; Costa, MI; Gonçalves AC; Geraldes, C; Sarmento-Ribeiro AB. "Modulação do NF-kB em modelos de mieloma múltiplo resistentes a inibidores de proteassoma". Paper presented in 31ª Sabatina de Hematologia, 2023.
  13. Lopes, MR; Jorge, J; Alves, R; Geraldes, C; Gonçalves AC; Sarmento-Ribeiro, AB. "Inibição do NRF2 como nova abordagem terapêutica em neoplasias linfóides sensíveis e resistentes ao bortezomib – Estudo preliminar". Paper presented in 31ª Sabatina de Hematologia, 2023.
  14. Alves, R; Silva, I; Costa, MI; Lapa, B; Jorge, J; Gonçalves AC; Sarmento-Ribeiro, AB. "Buparlisib a promising therapeutic approach in chronic myeloid leukemia resistant to imatinib". Paper presented in EHA 2023 Hybrid Congress, 2023.
  15. Alves, R; Almeida, AS; Costa, MI; Lapa, B; Jorge, J; Gonçalves AC; Geraldes, C; Sarmento-Ribeiro, AB. "Molecular mechanisms of resistance to immunomodulators in multiple myeloma: An in vitro study". Paper presented in EHA 2023 Hybrid Congress, 2023.
  16. Lapa, B; Costa, MI; Figueiredo, D; Jorge, J; Alves, R; Monteiro, AR; Silva, MR; et al. "The therapeutic potential of AZD-7648, a DNA-PK inhibitor, on acute myeloblastic leukemia". Paper presented in EACR congress 2023, 2023.
  17. Magalhães, M; Domínguez-Martín, E; Jorge, J; Gonçalves AC; Oliveira, P; Efferth, T; Rijo, P; Cabral, C. "Unravelling an abietane diterpenoid with very promising chemotherapeutic potential against glioblastoma cells". Paper presented in 71st International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research, 2023.
  18. Lapa, B; Costa, MI; Figueiredo, D; Jorge, J; Alves, R; Monteiro, AR; Sarmento-Ribeiro, AB; Gonçalves AC. "Modulação da DNA-PK no tratamento da leucemia mieloblástica aguda - um estudo in vitro". Paper presented in Encontro nacional de Jovens Investigadores em Oncologia, 2023.
  19. Costa, MI; Lapa, B; Alves, R; Jorge, J; Sarmento-Ribeiro AB; Gonçalves AC. "O potencial terapêutico do zinco na leucemia mieloblástica aguda: efeito citotóxico, citostático e genotóxico.". Paper presented in Encontro nacional de Jovens Investigadores em Oncologia, 2023.
  20. Lapa, B; Costa, MI; Jorge, J; Alves, R; Sarmento-Ribeiro AB; Gonçalves AC. "Modulation of PARP1/2 and CHK1 as a novel treatment for acute myeloid leukemia - in vitro study". Paper presented in III ASPIC-ASEICA International Meeting – Cancer Immunology, Tumor Microenvironment and Metastasis, 2023.
  21. Costa, MI; Lapa, B; Jorge, J; Alves, R; Sarmento-Ribeiro AB; Gonçalves AC. "Zinc in the modulation of the DNA damage response: preventive, genotoxic, and cytotoxic roles in acute myeloid leukemia". Paper presented in III ASPIC-ASEICA International Meeting – Cancer Immunology, Tumor Microenvironment and Metastasis, 2023.
  22. Jorge, J; Gonçalves AC; Berral-Gonzalez, A; Alves, R; De Las Rivas J; Sarmento Ribeiro AB. "Tumor educated platelets signature allow to identify and predict the survival of multiple myeloma patients". Paper presented in III ASPIC-ASEICA International Meeting ¿ Cancer Immunology, Tumor Microenvironment and Metastasis, 2023.
  23. Alves, R; Ventura, F; Jorge, J; Marques, G; Coucelo, M; Diamond, J; Freitas-Tavares, P; et al. "Influência das variantes genéticas de genes relacionados com o stresse oxidativo no prognóstico e resposta à terapêutica na leucemia mielóide crónica". Paper presented in Reunião Anual da Sociedade Portuguesa de Hematologia (SPH), 2023.
  24. Portelinha, AP; Almeida, AS; Constantino, B; Figueiredo, D; Santiago H; Silva, I; Costa, MI; et al. "The therapeutic potential of niraparib in lymphoid malignancies". Paper presented in 5th Annual Conference STRATAGEM CA17104, 2023.
  25. Santiago, H; Constantino, B; Costa, MI; Lapa, B; Jorge, J; Alves, R; Gonçalves AC; Sarmento-Ribeiro, AB. "O impacto da inibição da glutaminólise em monoterapia e em combinação com modularadores epigenéticos na leucemia linfocítica crónica – Resultados preliminares.". Paper presented in 30ª Sabatina de Hematologia, 2022.
  26. Constantino, B; Santiago, H; Costa, MI; Lapa, B; Jorge, J; Alves, R; Gonçalves, AC; Sarmento-Ribeiro, AB. "Potencial terapêutico da inibição do NRF2 na leucemia linfocítica crónica em associação com ibrutinib – Estudos preliminares in vitro". Paper presented in 30ª Sabatina de Hematologia, 2022.
  27. Serambeque, B; Carvalho, MJ; Pereira, NAM; Gonçalves, AC; Costa, AC; Pineiro, M; Pinho e Melo, TMVD; Botelho, MF; Laranjo, M. "erapia fotodinâmica no cancro do endométrio: uma potencial abordagem terapêutica conservadora?". Paper presented in 2ª Jornadas da Competência de Patologia Experimental – VII Congresso Luso-Brasileiro de Patologia Experimental e XVII Simpósio de Patologia Experimental., 2022.
  28. Silva, I; Jorge, J; Costa, MI; Lapa, B; Alves, R; Gonçalves, AC; Sarmento-Ribeiro, AB. "Potencial terapêutico do buparlisib na leucemia mielóide crónica sensível e resistente ao imatinib – Estudo preliminar.". Paper presented in Reunião Anual da Sociedade Portuguesa de Hematologia (SPH), 2022.
  29. Portelinha, AP; Costa, MI; Lapa, B; Jorge, J; Alves, R; Sarmento-Ribeiro, AB; Gonçalves, AC. "Potencial terapêutico do niraparib em neoplasias linfóides – Estudos in vitro". Paper presented in Reunião Anual da Sociedade Portuguesa de Hematologia (SPH), 2022.
  30. Lapa, B; Costa, MI; Jorge, J; Alves, R; Sarmento-Ribeiro, AB; Gonçalves AC. "Potencial terapêutico de moduladores dos sistemas de reparação do DNA na leucemia mieloblástica Aguda – Estudo preliminar in vitro.". Paper presented in Reunião Anual da Sociedade Portuguesa de Hematologia (SPH), 2022.
  31. Figueiredo, D; Costa, MI; Lapa, B; Jorge, J; Alves, R; Sarmento-Ribeiro, AB; Gonçalves AC. "Caracterização dos sistemas de reparação do DNA na leucemia mieloblástica aguda – Estudo preliminar in vitro.". Paper presented in Reunião Anual da Sociedade Portuguesa de Hematologia (SPH), 2022.
  32. Constantino, B; Alves, R; Santiago, H; Costa, MI; Lapa, B; Jorge, J; Carda,JP; Gonçalves AC; Sarmento-Ribeiro, AB. "Potencial terapêutico de inibidores do NRF2 na leucemia linfocítica crónica em associação com o ibrutinib: Estudos in vitro.". Paper presented in Reunião Anual da Sociedade Portuguesa de Hematologia (SPH), 2022.
  33. Silva, I; Portelinha, AP; Almeida, AS; Constantino, B; Figueiredo, D; Santiago, H; Jorge, J; et al. "Therapeutic potential of Buparlisib in Chronic Myeloid Leukemia - Preliminary results". Paper presented in 5th Annual Conference STRATAGEM CA17104, 2022.
  34. Santiago, H; Constantino, B; Costa, MI; Jorge, J; Alves, R; Gonçalves AC; Sarmento-Ribeiro AB. "Glutaminolysis inhibition in monotherapy and in combination with epigenetic modulators and ibrutinib on a chronic lymphocytic leukemia cell model – Preliminary results". Paper presented in 5th Annual Conference STRATAGEM CA17104, 2022.
  35. Magalhães, M; Domínguez-Martín, EM; Jorge, J; Gonçalves AC; Díaz-Lanza, AM; Manadas, B; Efferth, T; Rijo, P; Cabral, C. "Chemotherapeutic potential of the natural drug lead Royleanone against glioblastoma cells". Paper presented in 5th Annual Conference STRATAGEM CA17104, 2022.
  36. Lapa, B; Costa, MI; Jorge, J; Alves, R; Sarmento Ribeiro AB; Gonçalves AC. "Modulation of DNA damage repair in the treatment of acute myeloblastic leukemia in vitro study". Paper presented in 5th Annual Conference STRATAGEM CA17104, 2022.
  37. Jorge, J; Santos, D; Alves, R; Gonçalves AC; Girão, H; Catarino, S; Melo, JB; Sarmento Ribeiro AB. "Therapeutic inhibition of Heat sock protein 90 in chronic myeloid leukemia - A new therapeutic approach to circumvent imatinib resistance". Paper presented in 5th Annual Conference STRATAGEM CA17104, 2022.
  38. Figueiredo, D; Costa, MI; Lapa, B; Jorge, J; Alves, R; Sarmento Ribeiro AB; Gonçalves AC. "Characterization of DNA Repair Systems in Acute Myeloblastic Leukemia". Paper presented in 5th Annual Conference STRATAGEM CA17104, 2022.
  39. Constantino, B; Santiago, H; Costa, MI; Lapa, B; Jorge, J; Alves, R; Gonçalves AC; Carda, JP; Sarmento-RIbeiro, AB. "Therapeutic potential of the NRF2 inhibition in chronic lymphocytic leukemia with association with ibrutinib – Studies in vitro". Paper presented in 5th Annual Conference STRATAGEM CA17104, 2022.
  40. Alves, R; Gonçalves AC; Jorge, J; Almeida, A; Sarmento-Ribeiro AB. "Overcoming imatinib resistance with a P-gP and BCRP inhibitor". Paper presented in 5th Annual Conference STRATAGEM CA17104, 2022.
  41. Oliveira, I; Gaspar, T; Luís, M; Farinha, D; Alves, R; Jorge, J; Lapa, B; et al. "Partenolide: potencial terapêutico em mieloma múltiplo resistente a inibidores de proteasoma". Paper presented in 2º Encontro nacional de Jovens Investigadores em Oncologia, 2021.
  42. Gaspar, T; Oliveira, I; Luis, M; Costa, MI; Jorge, J; Lapa, B; Alves, R; Gonçalves AC; Sarmento-Ribeiro, AB. "Potencial terapêutico de moduladores epigenéticos na leucemia linfocítica cronica". Paper presented in 2º Encontro nacional de Jovens Investigadores em Oncologia, 2021.
  43. Costa, MI; Lapa, B; Alves, R; Jorge, J; Sarmento-Ribeiro, AB; Gonçalves AC. "O zinco na modulação dos efeitos antiproliferativos e citotóxicos da citarabina e olaparib na leucemia mieloide aguda.". Paper presented in 2º Encontro nacional de Jovens Investigadores em Oncologia, 2021.
  44. Oliveira, I; Jorge, J; Lapa, B; Costa, MI; Gonçalves AC; Sarmento-Ribeiro, AB. "Partenolide: Potencial terapêutico em Mieloma Múltiplo resistente a inibidores de proteasoma". Paper presented in Reunião Anual da Sociedade Portuguesa de Hematologia (SPH), 2021.
  45. Pais, AS; Laranjo, M; Reis, C; Reis, S; Sousa, AP; Silva, F; Jorge, J; et al. "Angiogenesis stimulation of cryopreserved ovarian tissue". Paper presented in 27th European Congress of Obstetrics and Gynaecology, 2021.
  46. Correia-Barros, G; Serambeque, B; Carvalho, MJ; Pereira, NAM; Gonçalves AC; Pineiro, M; Pinho e Melo, TMVD; Botelho, MF; Laranjo, M. "Evaluation of the Effectiveness of Photodynamic Therapy based on Novel Chlorins on Endometrial Cancer". Paper presented in II ASPIC-ASEICA International Meeting – Current Trends in Precision Medicine in Cancer, 2021.
  47. Alves, R.; Gonçalves AC; Jorge, J.; Freitas-Tavares, P.; Pereira, A.; Nascimento-Costa, JM; Sarmento-Ribeiro, AB. "Everolimus - a mTOR inhibitor as a new drug for CML treatment". Paper presented in International Online Symposium on “New Therapeutic Tools Against Preclinical Models of Multidrug Resistant Tumors”, 2020.
  48. Gomes, E.; Costa, MI; Magalhães, N.; Roque, D.; Alves, R.; Jorge, J.; Lapa, B.; et al. "O papel do eixo NRF2/KEAP1 no desenvolvimento da leucemia linfocítica crónica". Paper presented in Reunião Anual da Sociedade Portuguesa de Hematologia, 2020.
  49. Costa, MI; Magalhães, N.; Roque, D.; Gomes, E.; Alves, R.; Jorge, J.; Lapa, B.; et al. "O zinco na modeulação da reparação da lesão do DNA - Papel preventivo, genotóxico e citotóxico na leucemia mieloblástica aguda.". Paper presented in Reunião Anual da Sociedade Portuguesa de Hematologia, 2020.
  50. Magalhães, N.; Figueiredo, D.; Roque, D.; Costa, MI; Gomes, E.; Jorge, J.; Lapa, B.; et al. "O efeito do oltipraz no tratamento de leucemias agudas - Estudos in vitro". Paper presented in Reunião Anual da Sociedade Portuguesa de Hematologia, 2020.
  51. Lapa, B.; Alves, R.; Jorge, J.; Cortesão, E.; Ribeiro, AB; Pereira, A.; Ribeiro, L.; Gonçalves AC; Sarmento-Ribeiro, AB. "O eixo EPO-EPOR como biomarcador de resposta ao tratamento com agentes estimuladores da eritropoiese na sindrome mielodisplásica - Resultados preliminares". Paper presented in Reunião Anual da Sociedade Portuguesa de Hematologia, 2020.
  52. Costa, MI; Magalhães, N.; Roque, D.; Gomes, E.; Alves, R.; Jorge, J.; Lapa, B.; Sarmento-Ribeiro, AB; Gonçalves AC. "O duplo papel do zinco na modulação da resposta à lesão do DNA - O contexto preventivo e tumoral". Paper presented in 2º Encontro nacional de Jovens Investigadores em Oncologia, 2020.
  53. Gomes, E.; Costa, MI; Magalhães, N.; Roque, D.; Alves, R.; Jorge, J.; Carda, JP; et al. "O stress oxidativo na leucemia linfocítica crónica: O papael do eixo NRF2/KEAP1 no desenvolvimento da doença". Paper presented in 2º Encontro nacional de Jovens Investigadores em Oncologia, 2020.
  54. Figueiredo, D.; Jorge, J.; Alves, R.; Lapa, B.; Gonçalves AC; Sarmento-Ribeiro, AB. "Modulação de NRF2 como nova abordagem terapêutica em LMA - estudos In vitro". Paper presented in 2º Encontro nacional de Jovens Investigadores em Oncologia, 2020.
  55. Lapa, B.; Alves, R.; Jorge, J.; Cortesão, E.; Ribeiro, AB; Pereira, A.; Ribeiro, L.; Gonçalves AC; Sarmento-Ribeiro, AB. "O eixo EPO-EPOR como biomarcador de prognóstico e resposta ao tratamento na síndrome mielodisplásica". Paper presented in 2º Encontro nacional de Jovens Investigadores em Oncologia, 2020.
  56. Magalhães, N.; Roque, D.; Costa, MI; Figueiredo, D.; Gomes, E.; Jorge, J.; Lapa, B.; et al. "O efeito terapêutico do Oltipraz e do Brusatol na leucemia linfoblástica aguda". Paper presented in 2º Encontro nacional de Jovens Investigadores em Oncologia, 2020.
  57. Gonçalves AC; Silva, D.; Marques, B.; Jorge, J.; Alves, R.; Ribeiro, AB; Cortesão, E.; Nascimento-Costa, JM; Sarmento-Ribeiro, AB. "Aldehyde dehydrogenase genetic variants influence the risk myelodysplastic syndromes and acute myeloid leukemia development and progression". Paper presented in 25th Congress of the European Hematology Association, 2020.
  58. Alves, R.; Gonçalves AC; Carda, JP; Jorge, J.; Duarte, S.; Pereira, A.; Ribeiro, IP; et al. "Role of epigenetics in chronic lymphocytic leukemia pathogenesis and treatment". Paper presented in 25th Congress of the European Hematology Association, 2020.
  59. Alves, R.; Gonçalves AC; Jorge, J.; Afonso, C.; Roque, A.; Paiva, A.; Ribeiro, L.; Geraldes, C.; Sarmento-Ribeiro, AB. "Relevance of NF-kB and NRF2 transcription factors into multiple myeloma pathophysiology – A preliminary study". Paper presented in CIMAGO Meeting – Challenges in Oncobiology, 2020.
  60. Jorge, J.; Estevam, A.; Alves, R.; Lapa, B.; Nascimento-Costa, JM; Gonçalves AC; Sarmento-Ribeiro, AB. "STAT5 – A new therapeutic target in acute lymphoblastic leukemia?". Paper presented in CIMAGO Meeting – Challenges in Oncobiology, 2020.
  61. Silva, D.; Gonçalves AC; Marques, B.; Jorge, J.; Alves, R.; Ribeiro, AB; Cortesão, E.; Nascimento-Costa, JM; Sarmento-Ribeiro, AB. "Aldehyde dehydrogenase polymorphisms: The role in myelodysplastic syndromes and acute myeloid leucemia.". Paper presented in CIMAGO Meeting – Challenges in Oncobiology, 2020.
  62. Gomes, R.; Gonçalves AC; Jorge, J.; Alves, R.; Pereira, A.; Sarmento-Ribeiro, AB; Nascimento-Costa, JM. "IREB2 rs17483548 single nucleotide polymorphism is associated with colorectal cancer". Paper presented in CIMAGO Meeting – Challenges in Oncobiology, 2020.
  63. Figueiredo, D.; Jorge, J.; Alves, R.; Lapa, B.; Gonçalves AC; Sarmento-Ribeiro, AB. "NRF2 modulation as a new therapeutic approach in AML – In vitro studies". Paper presented in CIMAGO Meeting – Challenges in Oncobiology, 2020.
  64. Carda, JP; Alves, R.; Jorge, J.; Duarte, S.; Pereira, A.; Ribeiro, IP; Ribeiro, L.; Gonçalves AC; Carreira, IM. "Epigenetics in chronic lymphocytic leukemia - Role in pathogenesis and treatment". Paper presented in CIMAGO Meeting – Challenges in Oncobiology, 2020.
  65. Magalhães, N.; Roque, D.; Costa, MI; Gomes, E.; Jorge, J.; Alves, R.; Lapa, B.; Gonçalves AC; Sarmento-Ribeiro, AB. "Therapeutic effect of Oltipraz in acute lymphoblastic leukemia – Preliminary in vitro studies". Paper presented in CIMAGO Meeting – Challenges in Oncobiology, 2020.
  66. Costa, MI; Magalhães, N.; Roque, D.; Gomes, E.; Alves, R.; Jorge, J.; Lapa, B.; et al. "Zinc as a genoprotective player of DNA damage response – Preliminary results". Paper presented in CIMAGO Meeting – Challenges in Oncobiology, 2020.
  67. Lapa, B.; Alves, R.; Jorge, J.; Cortesão, E.; Pereira, A.; Ribeiro, L.; Gonçalves AC; Sarmento-Ribeiro, AB. "EPO-EPOR axis as a prognostic and drug response biomarker in myelodysplastic syndrome – Preliminary results". Paper presented in CIMAGO Meeting – Challenges in Oncobiology, 2020.
Journal article
  1. Marto, Carlos Miguel; Laranjo, Mafalda; Gonçalves AC; Paula, Anabela; Jorge, Joana; Caetano-Oliveira, Rui; Sousa, Maria Inês; et al. "In Vitro Characterization of Reversine-Treated Gingival Fibroblasts and Their Safety Evaluation after In Vivo Transplantation". Pharmaceutics 16 2 (2024): 207. http://dx.doi.org/10.3390/pharmaceutics16020207.
    Published • 10.3390/pharmaceutics16020207
  2. Ana Catarina Matos; João Lorigo; Inês Alexandra Marques; Ana Margarida Abrantes; Matilde Jóia-Gomes; Pedro Sa-Couto; Ana Cristina Gonçalves; et al. "Anti-Algics in the Therapeutic Response of Breast and Urological Cancers". International Journal of Molecular Sciences (2023): https://doi.org/10.3390/ijms25010468.
    10.3390/ijms25010468
  3. Beatriz Lapa; Maria Inês Costa; Diana Figueiredo; Joana Jorge; Raquel Alves; Ana Raquel Monteiro; Beatriz Serambeque; et al. "AZD-7648, a DNA-PK Inhibitor, Induces DNA Damage, Apoptosis, and Cell Cycle Arrest in Chronic and Acute Myeloid Leukemia Cells". International Journal of Molecular Sciences (2023): https://www.mdpi.com/1422-0067/24/20/15331.
    10.3390/ijms242015331
  4. Jorge, Joana; Neves, Joana; Alves, Raquel; Geraldes, Catarina; Gonçalves, Ana Cristina; Sarmento-Ribeiro, Ana Bela. "Parthenolide Induces ROS-Mediated Apoptosis in Lymphoid Malignancies". International Journal of Molecular Sciences 24 11 (2023): 9167. http://dx.doi.org/10.3390/ijms24119167.
    10.3390/ijms24119167
  5. Costa, Maria Inês; Sarmento-Ribeiro, Ana Bela; Gonçalves, Ana Cristina. "Zinc: From Biological Functions to Therapeutic Potential". International Journal of Molecular Sciences 24 5 (2023): 4822. http://dx.doi.org/10.3390/ijms24054822.
    10.3390/ijms24054822
  6. Cavalcante, Suiane; Viamonte, Sofia; Cadilha, Rui S.; Ribeiro, Ilda P.; Gonçalves, Ana Cristina; Sousa-Venâncio, João; Gouveia, Marisol; et al. "Maximal Exercise Improves the Levels of Endothelial Progenitor Cells in Heart Failure Patients". Current Issues in Molecular Biology 45 3 (2023): 1950-1960. http://dx.doi.org/10.3390/cimb45030125.
    10.3390/cimb45030125
  7. Ribeiro, Hugo; Alves, Raquel; Jorge, Joana; Gonçalves, Ana Cristina; Sarmento-Ribeiro, Ana Bela; Teixeira-Veríssimo, Manuel; Dourado, Marília; Andrade, José Paulo. "Platelet Membrane Proteins as Pain Biomarkers in Patients with Severe Dementia". Biomedicines 11 2 (2023): 380. http://dx.doi.org/10.3390/biomedicines11020380.
    10.3390/biomedicines11020380
  8. Alves, Raquel; Santos, Diogo; Jorge, Joana; Gonçalves, Ana Cristina; Catarino, Steve; Girão, Henrique; Melo, Joana Barbosa; Sarmento-Ribeiro, Ana Bela. "Alvespimycin Inhibits Heat Shock Protein 90 and Overcomes Imatinib Resistance in Chronic Myeloid Leukemia Cell Lines". Molecules 28 3 (2023): 1210. http://dx.doi.org/10.3390/molecules28031210.
    10.3390/molecules28031210
  9. Marques, Mário Pedro; Neves, Beatriz Guapo; Varela, Carla; Zuzarte, Mónica; Gonçalves, Ana Cristina; Dias, Maria Inês; Amaral, Joana S.; et al. "Essential Oils from Côa Valley Lamiaceae Species: Cytotoxicity and Antiproliferative Effect on Glioblastoma Cells". Pharmaceutics 15 2 (2023): 341. http://dx.doi.org/10.3390/pharmaceutics15020341.
    10.3390/pharmaceutics15020341
  10. Dana Jurkovicova; Christiana M. Neophytou; Ana Cipak Gašparovic; Ana Cristina Gonçalves. "DNA Damage Response in Cancer Therapy and Resistance: Challenges and Opportunities". International Journal of Molecular Sciences (2022): https://doi.org/10.3390/ijms232314672.
    10.3390/ijms232314672
  11. Magalhães, Mariana; Domínguez-Martín, Eva María; Jorge, Joana; Gonçalves, Ana Cristina; Díaz-Lanza, Ana María; Manadas, Bruno; Efferth, Thomas; Rijo, Patrícia; Cabral, Célia. "Parvifloron D-based potential therapy for glioblastoma: Inducing apoptosis via the mitochondria dependent pathway". Frontiers in Pharmacology 13 (2022): http://dx.doi.org/10.3389/fphar.2022.1006832.
    10.3389/fphar.2022.1006832
  12. Gonçalves, Ana Cristina. "Oxidative stress and high-density lipoprotein cholesterol: Cause or consequence?". Revista Portuguesa de Cardiologia 41 10 (2022): 841-842. http://dx.doi.org/10.1016/j.repc.2022.06.006.
    10.1016/j.repc.2022.06.006
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  70. Brito, A.F.; Ribeiro, M.; Abrantes, A.M.; Mamede, A.C.; Laranjo, M.; Casalta-Lopes, J.E.; Gonçalves, A.C.; et al. "New approach for treatment of primary liver tumors: The role of quercetin". Nutrition and Cancer 68 2 (2016): 250-266. http://www.scopus.com/inward/record.url?eid=2-s2.0-84962649551&partnerID=MN8TOARS.
    10.1080/01635581.2016.1145245
  71. Carrapita, J.; Abrantes, A.M.; Campelos, S.; Goncalves, A.C.; Cardoso, D.; Sarmento-Ribeiro, A.B.; Rocha, C.; et al. "Impact of splenic artery ligation after major hepatectomy on liver function, regeneration and viability". Scientific Reports 6 (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-84991065517&partnerID=MN8TOARS.
    10.1038/srep34731
  72. Mendes, J.; Gonçalves, A.C.; Alves, R.; Jorge, J.; Pires, A.; Ribeiro, A.; Sarmento-Ribeiro, A.B.. "L744,832 and Everolimus Induce Cytotoxic and Cytostatic Effects in Non-Hodgkin Lymphoma Cells". Pathology and Oncology Research 22 2 (2016): 301-309. http://www.scopus.com/inward/record.url?eid=2-s2.0-84961205328&partnerID=MN8TOARS.
    10.1007/s12253-015-9998-4
  73. Gonçalves AC; Cortesão E; B Oliveiros; Alves V; Espadana AI; Rito LC; Magalhães E; et al. "Oxidative stress and mitochondrial dysfunction play a role in myelodysplastic syndrome development, diagnosis, and prognosis: a pilot study". Free Radic Res. 49 (2015): 1081-1094.
    Published • 10.3109/10715762.2015.1035268
  74. Gonçalves AC; Cortesão E; B Oliveiros; Alves V; Espadana AI; Rito L; Magalhães E; et al. "Oxidative stress levels are correlated with P15 and P16 gene promoter methylation in myelodysplastic syndrome patients". Clin Exp Med. 17 (2015): 1-10.
    Published • 10.1007/s10238-015-0357-2
  75. Alves R; Fonseca AR; Gonçalves AC; Ferreira-Teixeira M; Lima J; Abrantes AM; Alves V; et al. "Drug transporters play a key role in the complex process of Imatinib resistance in vitro". Leukemia Research 39 3 (2015): 355-360.
    Published • 10.1016/j.leukres.2014.12.008
  76. Brito AF; Abrantes AM; Ribeiro M; Oliveira R; Casalta-Lopes JE; Gonçalves AC; Sarmento-Ribeiro AB; Tralhão JG; Botelho MF. "Fluorine-18 Fluorodeoxyglucose Uptake in Hepatocellular Carcinoma: Correlation with Glucose Transporters and p53 Expression". Journal of Clinical and Experimental Hepatology 1 (2015): 1-10.
    Published • 10.1016/j.jceh.2015.05.003
  77. Mendes, Fernando; Sales, Tiago; Domingues, Catia; Schugk, Susann; Abrantes, Ana Margarida; Goncalves, Ana Cristina; Teixo, Ricardo; et al. "Effects of X-radiation on lung cancer cells: the interplay between oxidative stress and P53 levels". Medical Oncology 32 12 (2015): http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000365128200011&KeyUID=WOS:000365128200011.
    10.1007/s12032-015-0712-x
  78. Mendes, F.; Domingues, C.; Teixo, R.; Abrantes, A.M.; Gonçalves, A.C.; Nobre-Gois, I.; Jacobetty, M.; et al. "The importance of radiotherapy on diffuse large B cell lymphoma treatment: a current review". Cancer and Metastasis Reviews 34 3 (2015): 511-525. http://www.scopus.com/inward/record.url?eid=2-s2.0-84942191574&partnerID=MN8TOARS.
    10.1007/s10555-015-9581-1
  79. Pereira, N.A.M.; Laranjo, M.; Pineiro, M.; Serra, A.C.; Santos, K.; Teixo, R.; Abrantes, A.M.; et al. "Novel 4,5,6,7-tetrahydropyrazolo[1,5-a]pyridine fused chlorins as very active photodynamic agents for melanoma cells". European Journal of Medicinal Chemistry 103 (2015): 374-380. http://www.scopus.com/inward/record.url?eid=2-s2.0-84941638935&partnerID=MN8TOARS.
    10.1016/j.ejmech.2015.08.059
  80. Mendes, F.; Antunes, C.; Abrantes, A.M.; Gonçalves, A.C.; Nobre-Gois, I.; Sarmento, A.B.; Botelho, M.F.; Rosa, M.S.. "Lung cancer: The immune system and radiation". British Journal of Biomedical Science 72 2 (2015): 78-84. http://www.scopus.com/inward/record.url?eid=2-s2.0-84942614118&partnerID=MN8TOARS.
    10.1080/09674845.2015.11666801
  81. Mamede, A.C.; Guerra, S.; Laranjo, M.; Carvalho, M.J.; Oliveira, R.C.; Gonçalves, A.C.; Alves, R.; et al. "Selective cytotoxicity and cell death induced by human amniotic membrane in hepatocellular carcinoma". Medical Oncology 32 12 (2015): http://www.scopus.com/inward/record.url?eid=2-s2.0-84945290678&partnerID=MN8TOARS.
    10.1007/s12032-015-0702-z
  82. Liberal, J.; Costa, G.; Carmo, A.; Vitorino, R.; Marques, C.; Domingues, M.R.; Domingues, P.; et al. "Chemical characterization and cytotoxic potential of an ellagitannin-enriched fraction from Fragaria vesca leaves". Arabian Journal of Chemistry (2015): http://www.scopus.com/inward/record.url?eid=2-s2.0-84951196550&partnerID=MN8TOARS.
    10.1016/j.arabjc.2015.11.014
  83. Gomes, A.R.; Abrantes, A.M.; Brito, A.F.; Laranjo, M.; Casalta-Lopes, J.E.; Gonçalves, A.C.; Sarmento-Ribeiro, A.B.; Botelho, M.F.; Tralhão, J.G.. "Influence of P53 on the radiotherapy response of hepatocellular carcinoma". Clinical and molecular hepatology 21 3 (2015): 257-267. http://www.scopus.com/inward/record.url?eid=2-s2.0-84982246163&partnerID=MN8TOARS.
    10.3350/cmh.2015.21.3.257
  84. Cortesão, E.; Tenreiro, R.; Ramos, S.; Pereira, M.; César, P.; Carda, J.P.; Gomes, M.; et al. "Serum erythropoietin as prognostic marker in myelodysplastic syndromes | Eritropoietina sérica como marcador prognóstico em síndrome mielodisplásica". Acta Medica Portuguesa 28 6 (2015): 720-725. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000368526700009&KeyUID=WOS:000368526700009.
    10.20344/amp.6518
  85. Santos K; Laranjo M; Abrantes AM; Brito AF; Gonçalves AC; Sarmento-Ribeiro AB; Botelho MF; et al. "Targeting triple-negative breast cancer cells with 6,7-bis(hydroxymethyl)-1H,3H-pyrrolo[1,2-c]thiazoles". European Journal of Medicinal Chemistry 22 79 (2014): 273-281.
    Published • 10.1016/j.ejmech.2014.04.008
  86. Priolli DG; Abrantes AM; Neves S; Gonçalves AC; Lopes CO; Martinez NP; Cardinalli IA; Sarmento-Ribeiro AB; Botelho MF. "Microenvironment influence on human colon adenocarcinoma phenotypes and matrix metalloproteinase-2, p53 and b-catenin tumor expressions from identical monoclonal cell tumor in the orthotopic model in athymic nude rats". Scand J Gastroenterol 49 3 (2014): 309-316.
    Published • 10.3109/00365521.2013.869350
  87. Laranjo M; Serra AC; Abrantes AM; Piñeiro M; Gonçalves AC; Casalta-Lopes JE; Carvalho L; et al. "2-Bromo-5-hydroxyphenylporphyrins for photodynamic therapy: Photosensitization efficiency, subcellular localization and in vivo studies". Photodiagnosis and Photodynamic Therapy 10 1 (2013): 51-61.
    Published • 10.1016/j.pdpdt.2012.05.003
  88. Gonçalves AC; Alves V; Silva T; Carvalho C; Oliveira CR; Sarmento-Ribeiro AB. "Oxidative stress mediates apoptotic effects of ascorbate and dehydroascorbate in human Myelodysplasia cells in vitro". Toxicology in Vitro 27 5 (2013): 1542-1549.
    Published • 10.1016/j.tiv.2013.03.009
  89. Mamede AC; Abrantes AM; Pedrosa L; Casalta-Lopes JE; Pires AS; Teixo RJ; Gonçalves AC; et al. "Beyond the Limits of Oxygen: Effects of Hypoxia in a Hormone-Independent Prostate Cancer Cell Line". ISRN Oncology 2013 (2013): 1-8.
    Published • 10.1155/2013/918207
  90. Gonçalves, A.C.; Barbosa-Ribeiro, A.; Alves, V.; Silva, T.; Sarmento-Ribeiro, A.B.. "Selenium compounds induced ros-dependent apoptosis in myelodysplasia cells". Biological Trace Element Research 154 3 (2013): 440-447. http://www.scopus.com/inward/record.url?eid=2-s2.0-84882704182&partnerID=MN8TOARS.
    10.1007/s12011-013-9749-x
  91. Tralhão, JG; Abrantes, AM; Gonçalves, AC; Hoti, E; Laranjo, M; Martins, R; Oliveiros, B; et al. "Study of hepatocellular function in the murine model following hepatic artery selective clamping". Acta Cirurgica Brasileira (2013):
    10.1590/s0102-86502013000900006
  92. Serra AC; Rocha-Gonsalves AM; Laranjo M; Abrantes AM; Gonçalves AC; Sarmento-Ribeiro AB; Botelho MF. "Synthesis of new 2-galactosylthiazolidine-4-carboxylic acid amides. Antitumor evaluation against melanoma and breast cancer cells". European Journal of Medicinal Chemistry 53 (2012): 398-402.
    Published • 10.1016/j.ejmech.2012.04.003
  93. Brito AF; Abrantes AM; Pinto-Costa C; Gomes AR; Mamede AC; Casalta-Lopes JE; Gonçalves AC; et al. "Hepatocellular Carcinoma and Chemotherapy: The Role of p53". Chemotherapy 58 5 (2012): 381-386.
    Published • 10.1159/000343656
  94. Brito A; Ribeiro M; Abrantes AM; Gonçalves AC; Sarmento-Ribeiro AB; Tralhão JG; Botelho MF. "Acção anti-cancerígena da Quercetina no Carcinoma Hepatocelular: o papel do GLUT-1". Revista Portuguesa de Cirurgia 25 (2012): 22-20.
    Published
  95. Mamede AC; Pires AS; Abrantes AM; Tavares SD; Gonçalves AC; Casalta-Lopes JE; Sarmento-Ribeiro AB; Maia JM; Botelho MF. "Cytotoxicity of Ascorbic Acid in a Human Colorectal Adenocarcinoma Cell Line (WiDr): in vitro and in vivo studies". Nutrition and Cancer 64 7 (2012): 1049-1057.
    Published • 10.1080/01635581.2012.713539
  96. Abrantes, A.M.; Serra, E.; Gonçalves, C.; Oliveiros, B.; Laranjo, M.; Sarmento-Ribeiro, A.B.; Rocha-Gonsalves, A.; Botelho, M.F.. "Tumour hypoxia and technetium tracers: In vivo studies". Current Radiopharmaceuticals 5 2 (2012): 99-105. http://www.scopus.com/inward/record.url?eid=2-s2.0-84857137003&partnerID=MN8TOARS.
    10.2174/1874471011205020099
  97. Balça-Silva, J.; Neves, S.S.; Gonçalves, A.C.; Abrantes, A.M.; Casalta-Lopes, J.; Botelho, M.F.; Sarmento-Ribeiro, A.B.; Silva, H.C.. "Effect of miR-34b overexpression on the radiosensitivity of non-small cell lung cancer cell lines". Anticancer Research 32 5 (2012): 1603-1610. http://www.scopus.com/inward/record.url?eid=2-s2.0-84861496878&partnerID=MN8TOARS.
  98. Costa, C.B.; Casalta-Lopes, J.; Andrade, C.; Moreira, D.; Oliveira, A.C.; Gonçalves, A.C.; Alves, V.; et al. "Farnesyltransferase inhibitors: Molecular evidence of therapeutic efficacy in acute lymphoblastic leukemia through cyclin D1 inhibition". Anticancer Research 32 3 (2012): 831-838. http://www.scopus.com/inward/record.url?eid=2-s2.0-84858765853&partnerID=MN8TOARS.
  99. Casalta-Lopes, J; Abrantes, AM; Laranjo, M; Rio, J; Gonçalves, AC; Oliveiros, B; Sarmento-Ribeiro, AB; Botelho, MF. "Efflux Pumps Modulation in Colorectal Adenocarcinoma Cell Lines: The Role of Nuclear Medicine". Journal of Cancer Therapy (2011):
    10.4236/jct.2011.23056
  100. Abrantes AM; Serra ME; Gonçalves AC; Rio J; Oliveiros B; Laranjo M; Rocha-Gonsalves AM; Sarmento-Ribeiro AB; Botelho MF. "Hypoxia-induced redox alterations and their correlation with 99mTc-MIBI and 99mTc-HL-91 uptake in colon cancer cells". Nuclear Medicine and Biology 37 2 (2010): 125-132.
    Published • 10.1016/j.nucmedbio.2009.11.001
  101. Oliveira R; Abrantes AM; Rio J; Gonçalves AC; Sarmento-Ribeiro AB; Carreira IM; Botelho MF. "Efeitos da radiação ionizante de 140 KeV em linhas celulares". Radioproteção 2 16 e 17 (2010): 60-69.
    Published
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2024 Dedifferentiated gingival fibroblasts present stem-like properties and multilineage-differentiation capacity CIMAGO congress
(Coimbra, Portugal)
2024 Therapeutic efficacy of PARP and CHK1 inhibition in combination with cytarabine in acute myeloblastic leukemia: preliminary study in vitro CIMAGO congress
(Coimbra, Portugal)
2024 Can tumor educated platelets identify and predict survival of multiple myeloma patients? CIMAGO Congress
(Coimbra, Portugal)
2024 Zinc synergizes with cytarabine and olaparib increasing apoptosis and DNA damage in acute myeloblastic leukemia IV Metabolism, Ageing & Disease (MAD) Meeting
(Coimbra, Portugal)
2024 DNA-PK inhibition as new therapeutic approach in acute myeloblastic leukemia – an in vitro study IV Metabolism, Ageing & Disease (MAD) Meeting
(Coimbra, Portugal)
2024 Can tumor educated platelets identify and predict survival of multiple myeloma patients? IV Metabolism, Ageing & Disease (MAD) Meeting
(Coimbra, Portugal)
2024 Nature’s weapon against glioblastoma: unraveling the 7a-acetoxy-6ß-hydroxyroyleanone (Roy) antitumor mechanism of action IV Metabolism, Ageing & Disease (MAD) Meeting
(Coimbra, Portugal)
2023 Early detection as a route to sustainable health (invited speaker) Ecoliteracy Course
Department of LifeSciences, University of Coimbra (Coimbra, Portugal)
2023 A DNA-PK como alvo terapêutico na leucemia mieloblástica aguda: Um estudo in vitro Reunião Anual da Sociedade Portuguesa de Hematologia (SPH)
(Viseu, Portugal)
2023 Inibição da glutaminólise na resistência ao imatinib na leucemia mieloide crónica: Estudo in vitro. Reunião Anual da Sociedade Portuguesa de Hematologia (SPH)
(Viseu, Portugal)
2023 Inibição da glutaminólise na resistência ao imatinib na leucemia mieloide crónica: Estudo in vitro Reunião Anual da Sociedade Portuguesa de Hematologia (SPH)
(Viseu, Portugal)
2023 Cell Cultures Troubleshooting: Contaminations (invited speaker) X Cell Culture and Tissue Training Course
CIMAGO (Coimbra, Portugal)
2022 Assessment of drug resistance using flow cytometry (Invited speaker) Training School WG3 & WG4 – Applications of genomic, cytometry and in silico studies to the study of drug sensitivity and resistance mechanisms – Clinical implications
STRATAGEM (Coimbra, Portugal)
2022 Flow cytometry studies (hands-on session) ( Invited Speaker) Training School WG3 & WG4 – Applications of genomic, cytometry and in silico studies to the study of drug sensitivity and resistance mechanisms – Clinical implications.
STRATAGEM (Coimbra, Portugal)
2022 Cell Cultures Troubleshooting: Contaminations (invited speaker) IX Cell Culture and Tissue Training Course
CIMAGO (Coimbra, Portugal)
2022 Workshop | Escrita Científica (invited speaker) IV Fórum Pedagógico
Núcleo de Estudantes de Biologia (NEB) da Associação Académica de Coimbra (Coimbra, Portugal)
2022 Glutaminólise como alvo terapêutico na leucemia linfocítica crónica Reunião Anual da Sociedade Portuguesa de Hematologia (SPH)
(Tróia, Portugal)
2022 Mecanismos moleculares de resistência a imunomoduladores no mieloma múltiplo Reunião Anual da Sociedade Portuguesa de Hematologia (SPH)
(Tróia, Portugal)
2022 DNA methylation is correlated with oxidative stress in myelodysplastic syndrome – Relevance as prognostic markers 5th Annual Conference STRATAGEM CA17104
(Coimbra, Portugal)
2022 Zn in the modulation of the DNA damage response: preventive, genotoxic, and cytotoxic roles in acute myeloid leukemia 5th Annual Conference STRATAGEM CA17104
(Coimbra, Portugal)
2021 Cell cultures troubleshooting VIII Cell culture and Tissue training Course (Beyond the Microscope, Culturing life)
CIMAGO (Coimbra, Portugal)
2021 Escrita científica e estrutura de um trabalho científico. (invited speaker) Curso intensivo de metodologia científica em Medicina Dentária
Faculdade de Medicina da UC (Coimbra, Portugal)
2021 Avaliação do potencial terapêutico de moduladores do NRF2 em doentes com leucemia linfocítica crónica Reunião Anual da Sociedade Portuguesa de Hematologia (SPH)
(Espinho, Portugal)
2021 O zinco na modulação dos efeitos antiproliferativos e citotóxicos do olaparib e citarabina na Leucemia Mielóide Aguda Reunião Anual da Sociedade Portuguesa de Hematologia (SPH)
(Espinho, Portugal)
2021 Oxidative stress parameters can predict the response to erythropoiesis-stimulating agents in myelodysplastic syndrome patients 4th Annual Conference STRATAGEM CA17104
(Prague, Czech Republic)
2021 Unravelling resistance mechanisms to proteasome inhibitors in multiple multiple 4th Annual Conference STRATAGEM CA17104
(Prague, Czech Republic)
2020/11 Resistência adquirida a inibidores de proteasoma em mieloma múltiplo: Estudos in vitro. Reunião Anual da Sociedade Portuguesa de Hematologia
Sociedade Portuguesa de Hematologia
2020/11 Drug response prediction in CML: the value of microRNAs expression profile International Online Symposium on “New Therapeutic Tools Against Preclinical Models of Multidrug Resistant Tumors”,
COST Action 17104 (STRATAGEM) WG3
2020/09 Mecanismos moleculares associados à resistência adquirida a inibidores de proteasoma em mieloma múltiplo: Estudos in vitro 2º encontro nacional de Jovens Investigadores em Oncologia
Liga Portuguesa Contra o Cancro
2020 Acute effects of exercise-based cardiac rehabilitation session on endothelial and hematopoietic stem cells in patients with heart failure Reunião anual do Grupo de Estudo de Fisiopatologia do Esforço e Reabilitação Cardíaca (GEFERC) Avanços em Saúde
(Póvoa de Varzim, Portugal)
2020 An exercise training program increases the endothelial repair/regeneration of adults with cardiovascular risk factors Reunião anual do Grupo de Estudo de Fisiopatologia do Esforço e Reabilitação Cardíaca (GEFERC) Avanços em Saúde
(Póvoa de Varzim, Portugal)
2019 STAT5 - Um alvo terapêutico em leucemia linfoblástica aguda? Reunião Anual da Sociedade Portuguesa de Hematologia
Sociedade Portuguesa de Hematologia (Portugal)
2019 Transportadores de influxo/efluxo na leucemia mielóide crónica: Influência das variantes genéticas na susceptibilidade e na resposta à terapêutica Reunião Anual da Sociedade Portuguesa de Hematologia
Sociedade Portuguesa de Hematologia (Portugal)
2019 Oxidative stress and DNA methylation in myelodysplastic syndrome - Is there a link? (invited speaker) Conferences in Oncobiology
Faculty of Pharmacy, University of Porto, (Coimbra, Portugal)
2019 Therapeutic Potential of Gambogic Acid and Silibinin in Acute Myeloblastic Leukemia – in vitro studies. In4Med
(Coimbra, Portugal)
2019 Aldehyde dehydrogenases polymorphisms: Their role in myelodysplastic syndromes Diagnostic Master Class Novartis
(Coimbra, Portugal)
2019 Effect of Splenic Artery Ligation after ALPPS on viability, regeneration and liver function - Results from an experimental animal model Congresso Português de Hepatologia
(Coimbra, Portugal)
2019 Estimulação in vitro da angiogénese de tecido ovárico criopreservado 7º Congresso Português de Medicina da Reprodução
(Porto, Portugal)
2019 Radionuclide therapy with Radium-223: in vitro evaluation of radiobiological effects in metastatic prostate cancer cells 16th International Congress of Radiation Research (ICRR2019)
2018 Aldehyde dehydrogenases as potential biomarkers in myeloid neoplasias CIMAGO Scientific Meeting
Centro de Investigação em Meio Ambiente, Genética e Oncobiologia (Portugal)
2018 Ionizing radiation effects in a bladder and an esophageal cancer cell lines. 4th IPLeiria’s International Health Congress
IPLeiria (Portugal)
2018 Alvespimycin is a promising drug in resistant chronic myeloid leukemia 13th YES Meeting
Núcleo de Estudantes de Medicina, FMUP (Portugal)
2018 Metabolismo como alvo terapêutica na leucemia mieloide aguda - glicólise ou fosforilação oxidativa? Reunião Anual da Sociedade Portuguesa de Hematologia
Sociedade Portuguesa de Hematologia (Portugal)
2018 Alvespimicina: nova arma terapêutica na leucemia mieloide crónica Reunião Anual da Sociedade Portuguesa de Hematologia
Sociedade Portuguesa de Hematologia (Portugal)
2018 Papel da variabilidade genética das dna metiltransferases na predisposição e prognóstico da leucemia linfocítica crónica Reunião Anual da Sociedade Portuguesa de Hematologia
Sociedade Portuguesa de Hematologia (Portugal)
2017 Impacto da laqueação da artéria esplénica após hepatectomia major na função, regeneração e viabilidade. XXXVII Congresso Nacional de Cirurgia
Sociedade Portuguesa de Cirurgia (Portugal)
2017 Cytotoxic effects of parthenolide on lymphoid malignancies’ cell lines. YES Meeting
Nucleo de Estudantes de Medicina, FMUP (Portugal)
2017 Modulação epigenética em leucemia linfoblástica aguda B – Potencial terapêutico dos agentes hipometilantes e inibidores das desacetilases das histonas Reunião Anual da Sociedade Portuguesa de Hematologia
Sociedade Portuguesa de Hematologia (Portugal)
2017 Perfil de microRNAs na LMC - Potencial biomarcador de resposta ao imatinib. Reunião Anual da Sociedade Portuguesa de Hematologia
Sociedade Portuguesa de Hematologia (Portugal)
2016 Polymorphisms in oxidative stress related genes as prognostic and therapeutic biomarkers in chronic myeloid leukemia. 5th CIMAGO Congress
Centro de Investigação em Meio Ambiente, Genética e Oncobiologia (Portugal)
2016 Is NF-KB expression relevant in multiple myeloma patients treated with bortezomib as frontline regimen? 5th CIMAGO Congress
Centro de Investigação em Meio Ambiente, Genética e Oncobiologia (Portugal)
2016 Evaluation of the cytotoxic response of photodynamic therapy in combination with doxorubicin and methotrexate inosteosarcoma 5th CIMAGO Congress
Centro de Investigação em Meio Ambiente, Genética e Oncobiologia (Portugal)
2016 The synergic effect of photodynamic therapy and acetylsalicylic acid in colorectal and esophagus cancer cells 5th CIMAGO Congress
Centro de Investigação em Meio Ambiente, Genética e Oncobiologia (Portugal)
2016 The WNT pathway as a potential therapeutic target in acute myeloid leukemia. 11th YES Meeting
Núcleo de Estudantes de Medicina, FMUP (Portugal)
2016 Papel da variabilidade genética da via KEAP1-NRF2 na susceptibilidade e prognóstico de doentes com Leucemia Linfocítica Crónica. Reunião Anual da Sociedade Portuguesa de Hematologia
Sociedade Portuguesa de Hematologia (Portugal)
2016 MSH3 e BLM como factores de susceptibilidade e prognóstico em SMD Reunião Anual da Sociedade Portuguesa de Hematologia
Sociedade Portuguesa de Hematologia (Portugal)
2015 Impacto da expressão de NF-kB no prognóstico de doentes com mieloma múltiplo sintomático tratados com bortezomib em 1ª linha Janssen Hematology Meeting
Janssen Pharmaceutical (Portugal)
2015 Impacto de polimorfismos em genes moduladores do stresse oxidativo no prognóstico e resposta ao tratamento da de doentes com Leucemia Mieloide Crónica. Reunião Anual da Sociedade Portuguesa de Hematologia
Sociedade Portuguesa de Hematologia (Portugal)
2015 Avaliação do potencial terapêutico da inibição da via WNT em modelos in vitro de neoplasias hematológicas Reunião Anual da Sociedade Portuguesa de Hematologia
Sociedade Portuguesa de Hematologia (Portugal)
2015 O papel da via de sinalização WNT na identificação de marcadores de prognóstico e alvos terapêuticos na Leucemia Linfoblástica Aguda-B pediátrica - estudo preliminar Reunião Anual da Sociedade Portuguesa de Hematologia
Sociedade Portuguesa de Hematologia (Portugal)
2014 Effects of photodynamic therapy in cell proliferation and oxidative stress in a retinoblastoma cell line 28ª Actualizações em Oncologia 2014 - 3º Congresso do CIMAGO
Centro de Investigação em Meio Ambiente, Genética e Oncobiologia (Portugal)
2014 Butirato e irinotecano: uma nova abordagem para o tratamento do cancro colorretal. Semana Digestiva 2014
Sociedade Portuguesa de Gastrenterologia (Portugal)
2014 Polimorfismo em genes moduladores epigenéticos e do metabolismo do folato/metionina - influência nos níveis de metilação e no risco de desenvolver neoplasias mielóides. Reunião Anual da Sociedade Portuguesa de Hematologia
Sociedade Portuguesa de Hematologia (Portugal)
2014 Alterações induzidas pela hipóxia no metabolismo celular - Estudo in vitro em três linhas de células de cancro do cólon XXXIV Congresso Nacional de Cirurgia
Sociedade Portuguesa de Cirurgia (Portugal)
2014 May our diet interfere with tumor aggressiveness promoted by Warburg effect in colon cancer cells? 9th YES Meeting
Núcleo de Estudantes de Medicina, FMUC (Portugal)
2014 The interaction between p53 and oxidative stress levels in a Lymphoma cell line irradiaded with ionizing radiation. 2nd Congress of Croatia Chamber of Health profissionals
(Croatia)
2014 Influência do perfil genético de transportadores ABC no desenvolvimento de neoplasias mielóides Reunião Anual da Sociedade Portuguesa de Hematologia
Sociedade Portuguesa de Hematologia (Portugal)
2014 Butyrate and irinotecan as a new approach of the therapeutic of the colon cancer. Pharmacy Master Symposium
Escola Superior de Tecnologia da Saúde de Coimbra (Portugal)
2014 Alterations on cell metabolism induced by hypoxia In vitro study Colorectal Carcinoma. 28ª Actualizações em Oncologia 2014 - 3º Congresso do CIMAGO
Centro de Investigação em Meio Ambiente, Genética e Oncobiologia (Portugal)
2013 Avaliação dos niveis de TNF-e células do sistema imune em doentes com cancro do pulmão de não pequenas células submetidos a radioterapia. 1as Jornadas de Cancro do Pulmão do IPO de Coimbra
Instituto Português de Oncologia de Coimbra (Portugal)
2013 Ascorbic acid and its cytotoxic effect in melanoma: in vitro and in vivo studies 27ª Actualizações em Oncologia 2013 - 2º Congresso do CIMAGO
Centro de Investigação em Meio Ambiente, Genética e Oncobiologia (Portugal)
2013 Treatment of adenocarcinomas with neuroendocrine differentiation with metabolic radiotherapy and chemotherapy 27ª Actualizações em Oncologia 2013 - 2º Congresso do CIMAGO
Centro de Investigação em Meio Ambiente, Genética e Oncobiologia (Portugal)
2013 Epigenetic Changes in Monoclonal Gammopathies - A Possible Role in the Progression of MGUS to Multiple Myeloma 27ª Actualizações em Oncologia 2013 - 2º Congresso do CIMAGO
Centro de Investigação em Meio Ambiente, Genética e Oncobiologia (Portugal)
2013 Interference of proteasome inhibitor MG262 with Wnt and NF-KB pathways in an ovarian cancer cell-line 27ª Actualizações em Oncologia 2013 - 2º Congresso do CIMAGO
Centro de Investigação em Meio Ambiente, Genética e Oncobiologia (Portugal)
2013 The behaviour of MMP in the pathogenesis and in the progression from MGUS to MM 1st reSEARCH
Faculdade de Medicina da Universidade de Coimbra (Portugal)
2013 X radiation effects on Small cell Lung Cancer and Non-small Lung Cancer - an in vitro study 17th ECCO - 38th ESMO - 32nd ESTRO European Cancer Congress
ECCO, ESMO, ESTRO (Netherlands)
2013 The role of nuclear medicine in the study of multidrug resistance in hepatocelular carcinoma. 27ª Actualizações em Oncologia 2013 - 2º Congresso do CIMAGO
Centro de Investigação em Meio Ambiente, Genética e Oncobiologia (Portugal)
2013 Variabilidade Genética de Genes Relacionados com o Stresse Oxidativo - Papel no Desenvolvimento de Neoplasias Hematológicas. Reunião Anual da Sociedade Portuguesa de Hematologia
Sociedade Portuguesa de Hematologia (Portugal)
2013 Cellular and Molecular characterization of X Radiation effects, in small cell lung cancer and Non-Small Lung Cancer - an in vitro study I Annual Meeting Coimbra Health School, Jornadas Científicas de Análises Clínicas e Saúde Pública – Oncologia
Coimbra Health School (Portugal)
2013 Can epigenetic modulation be a new therapeutical approach to Diffuse Large B Cell Lymphoma? 4º Simpósio do PF2MUC – Personalized Medicine: myth or reality?
Núcleo de Estudantes de Medicina, FMUC (Portugal)
2013 The role of Vismodegib in Hematological Neoplasias Treatment 8th YES Meeting
Núcleo de Estudantes de Medicina, FMUP (Portugal)
2013 Oxidative stress vs gene methylation - A new risk factor in MDS patients? 27ª Actualizações em Oncologia 2013 - 2º Congresso do CIMAGO
27ª Actualizações em Oncologia 2013 - 2º Congresso do CIMAGO (Portugal)
2013 Cytotoxic Effects of ionizing Radiation in Cancer Cell Lines of Small Cell Lung Cancer and Large Diffuse B cell Lymphoma - A therapeutic tool. Regional European Biomedical Laboratory Science Congress, 4th Greek Medical Laboratory Technologists Conference
(Greece)
2012 18F-FDG and 18F-CHO: potential tools to explore the bioenergetics needs of prostate cancer? 26ª Actualizações em Oncologia 2012 - 1.º Congresso do CIMAGO
Centro de Investigação em Meio Ambiente, Genética e Oncobiologia (Portugal)
2012 TRAIL and Survivin Inhibitors - the therapeutic role in overcome relapse in Acute Lymphoblastic leucemia YES Meeting
Núcleo de Estudantes de Medicina, FMUP (Portugal)
2012 Ascorbic acid and its therapeutic potential against colorectal adenocarcinoma ESMO 14th World Congress on Gastrointestinal Cancer
European Society for Medical Oncology (Spain)
2012 Correlation between in vitro and in vivo 18FFDG uptake in breast cancer. 26ª Actualizações em Oncologia - 1.º Congresso do CIMAGO
Centro de Investigação em Meio Ambiente, Genética e Oncobiologia (Portugal)
2012 Vias de sinalização RAS/MAPK e PI3K/AKT/mTOR na LMC: qual o potencial terapêutico na resistência? Reunião Anual da Sociedade Portuguesa de Hematologia
Sociedade Portuguesa de Hematologia (Portugal)
2012 The behaviour of metalloproteinases -2, -8 and -9 in MGUS and Multiple Myeloma YES Meeting
Núcleo de Estudantes de Medicina, FMUP (Portugal)
2012 MNSOD and GPX1 polymorfisms – a possible role in MDS susceptibility. 26ª Actualizações em Oncologia 2012. 1.º Congresso do CIMAGO
Centro de Investigação em Meio Ambiente, Genética e Oncobiologia (Portugal)
2012 CD40 in oral squamous cell carcinoma potential role as a new therapeutic target 26ª Actualizações em Oncologia 2012. 1.º Congresso do CIMAGO
Centro de Investigação em Meio Ambiente, Genética e Oncobiologia (Portugal)
2011 Avaliação do perfil de metilação e do estado mutacional do gene TET2 em neoplasias mielóides: resultados preliminares Reunião Anual da Sociedade Portuguesa de Hematologia
Sociedade Portuguesa de Hematologia (Portugal)
2011 Avaliação do impacto da laqueação da artéria esplénica após hepatectomia major na função e na viabilidade hepatocelular . XIII Congresso Nacional de Medicina Nuclear
Sociedade Portuguesa de Medicina Nuclear (Portugal)
2011 Perfil de captação de 18F-FDG em carcinoma hepatocelular: correlação com a expressão de GLUT's 14ª Reunião Anual da Associação Portuguesa para o Estudo do Fígado
Associação Portuguesa para o Estudo do Fígado (Portugal)
2011 Prostate cancer: searching for its bioenergetic needs 1º simpósio PF2MUC-Todays scientific challenges
Núcleo de Estudantes de Medicina, FMUC (Portugal)
2011 Papel da variabilidade genética da MNSOD e GLPX na susceptibilidade para síndrome mielodisplásica. Reunião Anual da Sociedade Portuguesa de Hematologia
Sociedade Portuguesa de Hematologia (Portugal)
2011 Novos alvos terapêuticos no Linfoma Difuso de Grandes Células B – o papel da via do NF-Kb Reunião Anual da Sociedade Portuguesa de Hematologia
Sociedade Portuguesa de Hematologia (Portugal)
2011 Relevância prognóstica das mutações dos genes FLT3 E NPM1 em doentes com neoplasias mieloides . Reunião Anual da Sociedade Portuguesa de Hematologia
Sociedade Portuguesa de Hematologia (Portugal)
2011 Potencial Terapêutico de siRNA anti-FLT3 Em Neoplasias Hematológicas. Reunião Anual da Sociedade Portuguesa de Hematologia
Sociedade Portuguesa de Hematologia (Portugal)
2011 The RAS/RAF and AKT/mTOR pathways as therapeutic targets in Diffuse Large B-Cells Lymphoma. VI YES Meeting
Núcleo de Estudantes de Medicina, FMUP (Portugal)
2011 Expressão de MMP-2, MMP-8, MMP-9 na medula óssea de doentes com MGUS e MM. Reunião Anual da Sociedade Portuguesa de Hematologia
Sociedade Portuguesa de Hematologia (Portugal)
2011 Impacto da laqueação da artéria esplénica após hepatectomia major na função e viabilidade hepatocelular. XXXI Congresso Nacional de Cirurgia
(Portugal)
2011 Transportadores Membranares e Resistência ao Imatinib: Nova Abordagem Terapêutica em LMC. Reunião Anual da Sociedade Portuguesa de Hematologia
Sociedade Portuguesa de Hematologia (Portugal)
2010 Tumoral hypoxia: from synthesis to imaging 2nd IBILI Meeting
Instituto Biomédico de Investigação da Luz e da Imagem (Portugal)
2010 Mitochondria as a New Therapeutic Target in Cancer Young European Scientist Meeting
Núcelo de Estudantes de Medicina, FMUP (Portugal)
2009 Epigenética e Metabolismo do Folato/Vitamina B12 em doentes com SMD. Reunião Anual da Sociedade Portuguesa de Hematologia
Sociedade Portuguesa de Hematologia (Portugal)
2009 A mitocôndria como alvo terapêutico na SMD – potencial terapêutico dos catiões lipofílicos. XI Congresso da Sociedade Ibérica de Citometria
Sociedade Ibérica de Citometria (Portugal)
2009 Potential Therapeutic of a New Plant Product in Acute Promyelocytic Leukemia Young European Scientist Meeting
Núcleo de Estudantes de Medicina, FMUP (Portugal)
2009 A utilização de 99mTc-HL-91 na avaliação da hipóxia tumoral em adenocarcinoma colorectal - da síntese química aos estudos in vitro, in vivo e ex vivo XII Congresso Nacional de Medicina Nuclear
Sociedade Portuguesa de Medicina Nuclear (Portugal)
2009 MDR e a sua cinética de reversão em linhas celulares deadenocarcionoma colo-rectal. V Congresso Nacional de Técnicos de Medicina Nuclear.
Sociedade Portuguesa de Medicina Nuclear. (Portugal)
2009 Estudo do efeito da clampagem per-operatória da veia porta na função hepatocelular no modelo animal com fígado normal XXIX Congresso Nacional de Cirurgia
(Portugal)
2009 Influência do Polimorfismo ALA(9)VAL da MnSOD na Síndrome Mielodisplásica Reunião Anual da Sociedade Portuguesa de Hematologia
Sociedade Portuguesa de Hematologia (Portugal)
2009 Study of hepatocellular function in a murine model with normal liver after hepatic artery selective clamping Annual Congress of the European Association of Nuclear Medicine
European Association of Nuclear Medicine (Germany)
2009 Dequalinium: a New Approach on B-Cll Treatment? Young European Scientist Meeting
Núcleo de Estudantes de Medicina, FMUP (Portugal)
2009 Uptake kinetics studies of 99mTcO4- and 188ReO4- on CRL-1472 and MNNG-HOS cell lines European Association of Nuclear Medicine Congress
European Association of Nuclear Medicine
2009 Efeito dos moduladores de MDR em linhas celulares de adenocarcinoma colo-rectal XII Congresso Nacional de Medicina Nuclear
Sociedade Portuguesa de Medicina Nuclear (Portugal)
2009 Estudo do efeito da clampagem per-operatória selectiva da veia porta na função hepatocelular no modelo animal com fígado normal XII Congresso Nacional de Medicina Nuclear
Sociedade Portuguesa de Medicina Nuclear (Portugal)
2008 Participação da Mitocôndria e do Stress Oxidativo na Sindrome Mielodisplásica Reunião Anual da Sociedade Portuguesa de Hematologia
Sociedade Portuguesa de Hematologia (Portugal)
2008 Estudo do efeito da clampagem per-operatória (manobra de pringle) na função hepato-celular no modelo animal com hepatectomia sobre cirrose XXVIII Congresso Nacional da Sociedade Portuguesa de Cirurgia
Sociedade Portuguesa de Cirurgia (Portugal)
2008 Avaliação da metilação e apoptose em doentes com SMD Reunião Anual da Sociedade Portuguesa de Hematologia
Sociedade Portuguesa de Hematologia (Portugal)
2007 Impact of portal triad clamping (pringle maneuver) in hepatocellular function in the murine model with normal liver. European Association of Nuclear Medicine Congress
European Association of Nuclear Medicine (Denmark)
2006 Potential therapeutic approach of recombinant TRAIL in CML in blast crisis. 11th Congress of European Hematology Association
European Hematology Association (Netherlands)
2006 Protein Kinase Inhibitors In Acute Leukemia - A Preliminary Study In Cell Culture Reunião Anual da Sociedade Portuguesa de Hematologia
Sociedade Portuguesa de Hematologia (Portugal)
2006 Citotoxicidade entre 5-fluoracilo e enzaustaurin (inibidor da PKC-ß) em linha celular de adenocarcinoma colorectal – estudos preliminares V Congresso de Investigação em Medicina, Pedagogia e Ciência
Núcleo de Estudantes de Medicina, FMUC (Portugal)
2006 Inibidores da proteína cinase em leucemia aguda: estudo preliminar em linhas celulares. Reunião Anual da Sociedade Portuguesa de Hematologia
Sociedade Portuguesa de Hematologia (Portugal)
2006 Sinalização celular e cancro – Papel dos inibidores da farnesiltransferase em leucemias. V Congresso de Investigação em Medicina, Pedagogia e Ciência
Núcleo de Estudantes de Medicina, FMUC (Portugal)
2006 Effect of the PKC-beta inhibitor, enzastaurin, in acute leukemia. A preliminar study in cell culture Annual Meeting of American Society of Hematology
American Society of Hematology (United States)
2005 Bortezomib induz aumento da expressão de BAX e apoptose selectiva dos linfócitos B monoclonais. Reunião Anual da Sociedade Portuguesa de Hematologia
Sociedade Portuguesa de Hematologia (Portugal)
2005 Análise molecular da resposta à terapêutica na LMC: protocolo clássico vs Mesilato de Imatinib Reunião Anual da Sociedade Portuguesa de Hematologia
Sociedade Portuguesa de Hematologia (Portugal)
2005 Proteasome inhibitors may circumvent resistance to chemotherapy in acute lymphoblastic leukemia cells in culture Reunião Anual da Sociedade Portuguesa de Hematologia
Sociedade Portuguesa de Hematologia (Portugal)
2005 Correlação entre o gene BCR-ABL, o transcrito BCR-ABL e a resposta à terapêutica na LMC. Reunião Anual da Sociedade Portuguesa de Hematologia
Sociedade Portuguesa de Hematologia (Portugal)
2005 Phenotypical and Functional Characterization of CD4+CD25high Regulatory T Cells. IX Congresso da Sociedade Ibérica de Citometria
Sociedade Ibérica de Citometria (Portugal)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2023 - Current Molecular therapeutic targets in IDH1/2 mutant tumours: exploring the links between metabolism and DNA damage response
Supervisor
 Ciências da Saúde (PhD)
Universidade de Coimbra Faculdade de Medicina, Portugal
2023 - Current DNA DAMAGE AND DNA DAMAGE RESPONSE PROFILE IN GLIOMA: POTENTIAL BIOMARKERS FOR THERAPY RESPONSE
Supervisor
 Investigação Biomédica (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal
2023 - Current Influence of circadian clock genes in the Regulation of DNA damage repair in acute myeloid leukemia
Supervisor
 Biologia Celular e Molecular (Master)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2022 - Current Early detection, diagnosis and monitoring of Bone Marrow Failure Syndromes and Germline Predisposition to Myeloid neoplasms – The role of clonal haematopoiesis detection
Co-supervisor
 Ciências da Saúde (PhD)
Universidade de Coimbra Faculdade de Medicina, Portugal
2021 - Current Clinical implications of DNA damage repair in acute myeloid leukemia
Supervisor
 Ciências da Saúde (PhD)
Universidade de Coimbra Faculdade de Medicina, Portugal
2020/01 - Current Clinical relevance of platelets in mature B cell neoplasms: Role as non-invasive biomarkers and therapeutic delivery systems
Co-supervisor
 Health Sciences (PhD)
Universidade de Coimbra Faculdade de Medicina, Portugal
2022 - 2023 Stresse oxidativo no prognóstico e resposta aos inibidores de tirosina cinase na leucemia mieloide crónica: Relevância da variabilidade genética
Supervisor
 Bioquímica (Master)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2021 - 2022 The therapeutic potential of niraparib in lymphoid malignancies
Supervisor
 Bioquímica (Master)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2021 - 2022 Glutaminolysis inhibition, in monotherapy and in combination with epigenetic modulators and ibrutinib, on chronic lymphocytic leukemia
Supervisor
 Investigação Biomédica (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal
2020 - 2021 Caracterização dos Sistemas de Reparação do DNA na Leucemia Mieloblástica Aguda: Implicações na resposta à terapêutica
Supervisor
 Biomedicina Molecular (Master)
Universidade de Aveiro, Portugal
2020 - 2021 Avaliação de propriedades antitumorais de plantas do Vale do Côa
Co-supervisor
 Biodiversidade e Biotecnologia Vegetal (Master)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2019 - 2020 Parthenolide: therapeutic potential in multiple myeloma resistant to proteasome inhibitors.
Supervisor
 Bioquímica (Master)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2019 - 2020 Potencial terapêutico de moduladores do NRF2 na leucemia linfoblástica aguda- Estudos "in vitro"
Supervisor
 Química Medicinal (Master)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2019 - 2020 The role of micronutrients in the DNA damage response - The case of zinc in acute myeloid leukemia
Supervisor
 Investigação Biomédica (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal
2018 - 2019 Effects of DNMT1, DNMT3A and DNMT3B genes expression on Chronic Lymphocytic Leukemia
Co-supervisor
 Medicina (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal
2018 - 2019 Aldehyde dehydrogenase polymorphisms: the role in myelodysplastic syndromes and acute myeloid leukemia
Supervisor
 Medicina (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal
2018 - 2019 Metabolism as a therapeutic target in acute myeloid leukemic - Glycolysis or Oxidative phosphorylation
Supervisor
 Investigação Biomédica (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal
2017 - 2018 Genetic Variability of DNMT genes - Role in Chronic Lymphocytic Leukaemia predisposition and prognosis
Co-supervisor
 Investigação Biomédica (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal
2016 - 2017 GENE EXPRESSION OF NFE2L2 IN MYELODYSPLASTIC SYNDROME PATIENTS – CLINICAL IMPLICATIONS
Co-supervisor
 Medicina (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal
2014 - 2015 Antitumor activity of splicing inhibitor pladienolide B in erythroleukemia: a study in cell lines
Co-supervisor
 Medicina (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal
2013 - 2014 Epigenetic modulation: a new therapeutic approach in Diffuse Large B Cell Lymphoma
Co-supervisor
 Medicina (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal
2012 - 2013 Dequalinium: a new approach on leukaemia treatment?
Co-supervisor
 Mestrado Integrado em Medicina (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal
2012 - 2013 Epigenética: uma nova abordagem terapêutica na leucemia linfócitica crónica
Co-supervisor
 Mestrado Integrado em Medicina (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal
2012 - 2013 Potencial terapêutico de favenóides e ácidos flavenóicos na leucemia promielocítica aguda
Co-supervisor
 Mestrado Integrado em Medicina (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal
2012 - 2013 Moduladores epigenéticos no tratamento dos Linfomas Difusos de Grandes células B – Estudo experimental in vitro
Co-supervisor
 Mestrado Integrado em Medicina (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal
2011 - 2012 As Vias de Sinalização RAS/RAF e ATK/mTOR como alvos terapêuticos no tratamento do Linfoma Difuso de Grandes Células B
Co-supervisor
 Mestrado Integrado em Medicina (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal
2011 - 2012 Potencial terapêutico de inibidores do NF-KB em linfoma difuso de grandes células B
Co-supervisor
 Mestrado Integrado em Medicina (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal
2011 - 2012 Wnt/B-catenine, Hedgehog and Notch pathways as a therapeutic Target in Hematological neoplasias
Co-supervisor
 Investigação Biomédica (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal
2011 - 2011 Avaliação Molecular dos Mecanismos de Sensibilidade e Resistência ao Bortezomib: Implicações na Abordagem Terapêutica no Mieloma Múltiplo
Co-supervisor
 Investigação Biomédica (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2023 - 2024 IV MAD Meeting (2024) (2024)
Meeting (Member of the Organising Committee)
 Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia, Portugal
2023 - 2024 CIMAGO congress "Ambiente, Genética e Oncobiologia no século XXI – Desafios e oportunidades" (2024)
Congress (Member of the Organising Committee)
 Centro de Investigação em Meio Ambiente Genética e Oncobiologia, Portugal
2021 - 2022 STRATAGEM Training School -"Applications of genomic, cytometry and in silico studies to the study of drug sensitivity and resistance mechanisms – Clinical implications" (2022)
Workshop (Member of the Organising Committee)
 Universidade de Coimbra Faculdade de Medicina, Portugal

STRATAGEM COST-ACTION 17104, Italy
2021 - 2022 5th STRATAGEM Annual Conference (2022)
Congress (Member of the Organising Committee)
 Universidade de Coimbra Faculdade de Medicina, Portugal

STRATAGEM COST-ACTION 17104, Italy
2018 - 2018 CIMAGO Scientific Meeting (2018)
Congress (Member of the Organising Committee)
 Centro de Investigação em Meio Ambiente Genética e Oncobiologia, Portugal

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2022 Genetic and Epigenetic causes underlying recurrent pregnancy loss
(Thesis) Main arguer
 Diane Estanheiro Vaz (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal
2022 Glioblastoma: Genomic and Epigenomic Characterization and Biomarker Identification
(Thesis) Main arguer
 Gui Miguel Andrade da Rosa (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal
2022 Relatório de Estágio Mestrado em Análises Clínicas
(Thesis) Arguer
 Fernanda Liliana Carvalho da Silva (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2022 Relatório de Estágio - Mestrado em Análises Clínicas
(Thesis) Arguer
 Sofia Bento Machado Rosário (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2021 Photodynamic therapy as an innovative approach to Endometrial Cancer Stem Cells
(Thesis) Arguer
 Gabriela Correia Barros (Master)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2021 Relatório de Estágio de Mestrado em Análises Clínicas
(Thesis) Arguer
 Juliana Marques Simões (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2021 Desprescrição em cuidados continuados e paliativos: uma scoping review
President of the jury
 Ana Rita Pinto Amaral (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal
2021 Biomaterials for PET diagnosis
(Thesis) Arguer
 Margarida Gonçalves Santos (Master)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2021 Relatório de Estágio. Mestrado em Análises Clínicas
(Thesis) Arguer
 Dora Cristina Borrazeiro Boieiro (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2020/11 Relatório de Estágio
(Thesis) Main arguer
 Filipa de Oliveira Moreira (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2020/10 Relatório de Estágio
(Thesis) Arguer
 Márcia Alexandra de Andrade Costa Gonçalves (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2020/06 Sensitivity and resistance in chronic myeloid leukaemia to tyrosine kinase inhibitors: insights into molecular mechanisms
Thesis Member
 Raquel Fernanda da Silva Alves (PhD)
Universidade de Coimbra Faculdade de Medicina, Portugal
2020 Relatório de Estágio - Mestrado em Análises Clínicas
(Thesis) Arguer
 Márcia Alexandra de Andrade Costa Gonçalves (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2020 Relatório de Estágio - Mestrado em Análises Clínicas
(Thesis) Arguer
 Filipa de Oliveira Moreira (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2018 AS NECESSIDADES DOS CUIDADORES FAMILIARES DAS PESSOAS COM DEMÊNCIA INTEGRADAS EM UNIDADES DE CUIDADOS CONTINUADOS
(Thesis) Arguer
 Adriana Inês Fidalgo Carvalho (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal
2018 Genomic Characterization of Monoclonal Gammopathies Patients
(Thesis) Main arguer
 Alexandra Maria de Jesus Couto Oliveira (Master)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2017 Evidence for BCR-ABL oncoprotein packaging into extracellular vesicles released by BCR-ABL+ leukemia cells: possible implications on cellular response to STI571
(Thesis) Main arguer
 Alexandra Isabel Lopes Teixeira (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Ad Hoc journal article review

Journal title (ISSN) Publisher
2023 - Current BMC Oral Health
2023 - Current Cancer treatment and research communications
2023 - Current Oxidative Medicine and Cellular Longevity
2023 - Current PhytoMedicine
2022 - Current Biology
2022 - Current Biomedicines
2022 - Current Cell Transplantation
2022 - Current Clinical Epigenetics
2022 - Current Diagnostics
2022 - Current Life
2022 - Current Mitochondrion
2022 - Current Pharmaceutics
2022 - Current Revista Portuguesa de Cardiologia
2021 - Current Archives of Medical Research
2021 - Current Current Issues in Molecular Biology
2021 - Current EBioMedicine
2021 - Current Epigenomics
2021 - Current Experimental and Therapeutic Medicine
2021 - Current Int. J. Environmental Research and Public Health
2020 - Current Cancers
2020 - Current European Journal of Pharmacology
2020 - Current Hematology
2020 - Current International Journal of Molecular Sciences
2018 - Current Journal of Pediatric Genetics
2018 - Current Biomedicine & Pharmacotherapy
2017 - Current FEBS Open Bio
2017 - Current Arabian Journal of Chemistry
2017 - Current Acta Haematologica
2015 - Current Tumor Biology
2015 - 2017 Cancer Biotherapy & Radiopharmaceuticals

Association member

Society Organization name Role
2020 - Current Portuguese Association for CancerResearch (ASPIC) Member
2018 - Current Sociedade Portuguesa de Hematologia (SPH) Member
2012 - Current European Association for CancerResearch (EACR) Member

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2021 - Current Genética Molecular e Genómica Genética Clínica Laboratorial (Mestrado integrado) Universidade de Coimbra Faculdade de Medicina, Portugal
2021 - Current Investigação em Medicina Dentária – Do Laboratório à Clínica Ciências da Saúde (Doutoramento) Universidade de Coimbra Faculdade de Medicina, Portugal
2020/09 - Current Escrita e comunicação científica Medicina (Mestrado integrado) Universidade de Coimbra Faculdade de Medicina, Portugal
2020/09 - Current Biologia da Nutrição Medicina (Mestrado integrado) Universidade de Coimbra Faculdade de Medicina, Portugal
2020 - Current Gestão Laboratorial Genética Clínica Laboratorial (Mestrado integrado) Universidade de Coimbra Faculdade de Medicina, Portugal
2020 - Current Oncogenetic Genética Clínica Laboratorial (Mestrado integrado) Universidade de Coimbra Faculdade de Medicina, Portugal
2019 - Current Técnicas Experimentais I Patologia Experimental (Mestrado) Universidade de Coimbra Faculdade de Medicina, Portugal
2018 - Current Biologia Celular e Molecular I e II Medicina (Mestrado integrado) Universidade de Coimbra Faculdade de Medicina, Portugal
2011 - Current Practical lessons in the Oncobiology and Cancer Course from the Doctoral Programme in Health Sciences Ciências da Saúde (Doutoramento) Universidade de Coimbra Faculdade de Medicina, Portugal
2009/12 - Current Hematologia no Mestrado em Análises Clínicas Análises Clínicas (Mestrado integrado) Universidade de Coimbra Faculdade de Farmácia, Portugal
2005/01 - Current Biologia Molecular Aplicada Medicina (Mestrado integrado) Universidade de Coimbra Faculdade de Medicina, Portugal

Mentoring / Tutoring

Topic Student name
2022 - Current 26ª edição programa Ciência Viva no Laboratório As mutações como alvo para tratar o cancro
2012 - Current Exchange Programme from Núcleo de Estudantes de Medicina da Faculdade de Medicina da Universidade de Coimbra Exchange students

Other jury / evaluation

Activity description Institution / Organization
2019 - Current Member of the evaluation committee for Master Research Fellowships Universidade de Coimbra Faculdade de Medicina, Portugal
2023 - 2023 Reviewer of Carreras Postdoc Program Empowering Future Leaders to Fight Blood Cancers for Josep Carreras Leukaemia Research Institute/Agència de Gestió d'Ajuts Universitaris i de Recerca (AGAUR)
2021 - 2021 Reviewer of seed money CIMAGO projects program Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia, Portugal
2019 - 2019 Reviewer/Member of the evaluation committee of Investigators contracted by Decreto-Lei n.º 57/2016 and by Estímulo ao Emprego Científico programm. Universidade de Coimbra Faculdade de Medicina, Portugal

Fundação para a Ciência e a Tecnologia, Portugal
2012 - 2015 Reviewer of Liga Portuguesa Contra o Cancro/Pfizer grants Liga Portuguesa Contra o Cancro, Portugal
2012 - 2012 Reviewer of Liga Portuguesa Contra o Cancro/Celgene grants Liga Portuguesa Contra o Cancro, Portugal
Distinctions

Award

2023 1st Prize Experimental Work Poster
Sociedade Portuguesa de Hematologia, Portugal
2021 1st Prize Oral communication
Sociedade Portuguesa de Hematologia, Portugal
2020 1st Prize Oral communication Experimental Work
Sociedade Portuguesa de Hematologia, Portugal
2020 1st Prize for Best Speed-Talks/Posters
2019 1st Prize Poster competition Fundamental research
Universidade de Coimbra Faculdade de Medicina, Portugal
2019 Best Work
Novartis Farma SA, Portugal
2019 Best Poster
Sociedade Portuguesa de Medicina da Reprodução, Portugal
2019 2nd Best Poster
Sociedade Portuguesa de Hematologia, Portugal
2018 1st Prize in Parallel Sessions (Oncology and Molecular Oncology) (Co-author)
Young European Scientist Meeting, Portugal
2018 1st Prize Experimental Work Poster (1st Author)
Sociedade Portuguesa de Hematologia, Portugal
2018 3rd Best Oral Presentation (Author)
Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia, Portugal
2017 Best Oral Presentation in Translational Research
Universidade de Coimbra Faculdade de Medicina, Portugal
2016 2nd Best Oral Presentation (Co-author)
Sociedade Portuguesa de Hematologia, Portugal
2015 Best Poster
Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia, Portugal
2015 Best Experimental Poster (1st Author)
Sociedade Portuguesa de Hematologia, Portugal
2014 2nd Best Experimental Poster
Sociedade Portuguesa de Hematologia, Portugal
2014 Best Experimental Poster
Sociedade Portuguesa de Hematologia, Portugal
2014 Best Poster in Molecular Biology and Oncology (ex eaquo)
Young European Scientist Meeting, Portugal
2014 1st Prize Dr. António Marcelino - Casuísticas
Núcleo de Medicina Interna dos Hospitais Distritais, Portugal
2014 Best Poster in Molecular Biology and Oncology (ex eaquo)
Young European Scientist Meeting, Portugal
2013 Best Oral Presentation
Regional European Congress of Biomedical Laboratory Science & the 4th Greek Medical Laboratory Techn, Portugal
2013 Best Oral Presentation
1as Jornadas de Cancro do Pulmão do IPO de Coimbra, Portugal
2013 Best Experimental Poster
Sociedade Portuguesa de Hematologia, Portugal
2013 Best Experimental Work - Myeloproliferative syndromes
Sociedade Portuguesa de Hematologia, Portugal

Shire Pharmaceuticals Portugal Lda, Portugal
2013 Best Poster
Yes Meeting, Portugal
2012 Best oral presentation (First Prize)
Young European Scientist Meeting, Portugal
2012 Best poster (First Prize in Oncology and Molecular Biology)
Young European Scientist Meeting, Portugal
2012 Best poster (First Prize in Pathology and Medicine)
Young European Scientist Meeting, Portugal
2012 2nd Best Experimental Poster
Sociedade Portuguesa de Hematologia, Portugal
2012 Honorable mention - Oral Presentation (ex aequo)
Young European Scientist Meeting, Portugal
2012 Honorable mention - Oral Presentation (ex aequo)
Young European Scientist Meeting, Portugal
2011 Best Oral Presentation
Sociedade Portuguesa deCirurgia, Portugal
2011 Best Oral Presentation
Associação Portuguesa para o Estudo do Fígado, Portugal
2011 Best Oral presentation
XXXI Congresso Nacional de Cirurgia, Portugal
2011 2nd Best Experimental Poster
Sociedade Portuguesa de Hematologia, Portugal
2010 1st Prize - Best Oral Presentation
XI Jornadas JOCEM, Portugal
2009 2nd Prize Oral Presentation
Sociedade Portuguesa de Hematologia, Portugal
2009 Best Oral Presentation - Audience Prize
Young European Scientist Meeting, Portugal
2009 3rd Prize Oral Presentation
Young European Scientist Meeting, Portugal
2008 2nd Best Experimental Work
Sociedade Portuguesa de Hematologia, Portugal
2008 Best Clinical Work
X Jornadas JOCEM, Portugal
2007 2nd Best Experimental Poster
Sociedade Portuguesa de Hematologia, Portugal