Ana Catarina Leite Pereira (AA1B-AB56-F09A)

Curriculum Vitae

Ana Catarina Leite Pereira

Catarina got her PhD in Biomedical Sciences (ICBAS/UP) in 2017 and is currently an Associate Researcher at the Nanomedicine at the Translational Drug Delivery Group, Instituto de Investigação e Inovação em Saúde (I3S), were she leads a team on advanced modelling of musculoskeletal pediatric tumors. Currently she coordinates two projects on the development of a bioengineered 3D model of osteosarcoma, aiming at providing a tool to unravel tumor development, the metastatic process and to screen in a biologically relevant setting novel therapies and targeted nanomedicines. Catarina has been working in the biomedical engineering field for 15 years, being involved in multiple projects in the area of nanotechnology, immunomodulation, musculoskeletal disorders and disease in vitro modelling. She has participated in 10 international and national projects during her career (DISC REGENERATION, RESTORE, GENEGUT, DUO-DIO, EUROSPINE, among others). She has vast national/international network of collaborators from academia (i3S (other research groups), University of Oulu, Shanghai Jiao Tong University School of Medicine, and industry (FINNADVANCE, React4Life). Through her scientific path, Catarina has published 39 articles, displaying a h-index of 19 (source: scopus). She has participated in multiple dissemination actions (>30 participations) both in national and international conferences, building up her reputation and recognition by her peers, as can be perceived by the high number of citations (>1000) and invitations to act as an expert panel reviewer for international funding agencies, examiner, lecturer, invited speaker and integration of scientific and PhD Advisory committees. Catarina has supervised 4 trainees (BSc), 6 master students (two ongoing) and is currently supervising 3 PhD students. Her responsibility towards the scientific endeavor has not been restricted to research, she actively participates in public awareness actions for science dissemination in primary and secondary schools and exhibitions to general population. Catarina has contributed to secure funding of the Liga Portuguesa Contra o Cancro (15K euros) and FCT (50k euros) as Principal Investigator (PI), from Gilead Genese Program (35K euros) as co-PI and from the European Commission (H2020 RESTORE (5.4M Euros) and HORIZON-HLTH-2021-TOOL-06 GENEGUT (4.9M Euros) as a team member. Catarina has been recently elected SPLC-CRS Board Director (2024-2026) and is the vice-chair of the Nanotechnologies for Regenerative Medicine Working group of ETPN (European Technology Platform of Nanomedicines).

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Identification

Personal identification

Full name: Ana Catarina Leite Pereira

Citation names

Leite Pereira, Catarina

Author identifiers

Ciência ID: AA1B-AB56-F09A
ORCID iD: 0000-0001-8703-1245

Email addresses

catarina.pereira@i3s.up.pt (Professional)

Telephones

Telephone

(351) 226074900 (Professional)

Addresses

I3S/INEB . Rua Alfredo Allen, 208 , 4200-135, Porto, Porto, Portugal (Professional)

Websites

www.ineb.up.pt (Professional)
www.i3s.up.pt (Professional)

Knowledge fields

Medical and Health Sciences - Clinical Medicine - Oncology
Medical and Health Sciences - Medical Biotechnology - Health-Related Biotechnology
Medical and Health Sciences - Medical Biotechnology - Biomaterials
Medical and Health Sciences - Medical Biotechnology - Technologies Involving the Manipulation of Cells, Tissues, Organs or the Whole Organism
Medical and Health Sciences - Medical Biotechnology - Technologies Involving the Manipulation of Cells, Tissues, Organs or the Whole Organism
Natural sciences - Biological Sciences - Microbiology
Medical and Health Sciences - Other Medical Sciences

Languages

Language	Speaking	Reading	Writing	Listening	Peer-review
Portuguese (Mother tongue)
English	Proficiency (C2)	Proficiency (C2)	Proficiency (C2)	Proficiency (C2)	Proficiency (C2)
French	Beginner (A1)	Beginner (A1)	Beginner (A1)	Beginner (A1)	Beginner (A1)

Education

	Degree	Classification
2024/10/17 - 2024/12/06 Concluded	Building and Leading Research Teams (Outros) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2023/01/24 - 2023/01/24 Concluded	Data Management Plan & FAIR data management – from plan to practice (Outros) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2022/11/24 - 2022/11/24 Concluded	Course on Life Science Intellectual Property: Management and Exploitation, 1st edition (Outros) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2020 - 2021 Concluded	Research Ethics & Integrity Course (Outros) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal	N/A
2020 Attended	Workshop: Organoids and Advanced 3D in Vitro Models for Research in Health and Disease (Outros) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2019 Attended	Advanced Course in Flow Cytometry: From basic knowledge to advanced applications (Outros) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal	N/A
2017/07/19 Concluded	Ciências Biomédicas (Doutoramento) Universidade do Porto, Portugal "MESENCHYMAL STEM/STROMAL CELLS RECRUITMENT FOR INTERVERTEBRAL DISC REGENERATION" (THESIS/DISSERTATION)	Aprovada com Distinção
2017 Concluded	6th Advanced Summer School: Interrogations at the Biointerface - Research/Clinical Interface at the Spine (Outros) Instituto Nacional de Engenharia Biomédica, Portugal	N/A
2015 Concluded	5th Advanced Summer School - The Nano/medicine interface (Outros) Instituto Nacional de Engenharia Biomédica, Portugal Institut de Bioenginyeria de Catalunya, Spain
2013 Concluded	3rd Advanced Summer School - Interrogations at the Biointerface: Inflammation/Repair Interface (Outros) Instituto Nacional de Engenharia Biomédica, Portugal Institut de Bioenginyeria de Catalunya, Spain	N/A
2010 Concluded	Engenharia Biomédica (Mestrado) Universidade do Porto Faculdade de Engenharia, Portugal "Biosynthesis of Poly-gamma-Glutamic Acid and its application in Chitosan/gamma-PGA " (THESIS/DISSERTATION)	17
2009 Concluded	1st Advanced Summer School Interrogations at the Biointerface - Cancer/Regeneration Interface (Outros) Instituto Nacional de Engenharia Biomédica, Portugal Institut de Bioenginyeria de Catalunya, Spain	N/A
2008 Concluded	Biologia (Licenciatura) Universidade do Porto Faculdade de Ciências, Portugal "n/a" (THESIS/DISSERTATION)	14 (Classe c)

Affiliation

Science

	Category Host institution	Employer
2022/03/01 - Current	Auxiliary Researcher (Research)	Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
	Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2020/02/16 - 2023/02/28	Research Assistant (Research)	Instituto Nacional de Engenharia Biomédica, Portugal
	Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2018/06/01 - 2019/12/31	Research Assistant (Research)	Instituto Nacional de Engenharia Biomédica, Portugal

2017/10/01 - 2018/06/30	Postdoc (Research)	Instituto Nacional de Engenharia Biomédica, Portugal

2017/03/01 - 2017/08/31	Researcher (Research)	Instituto Nacional de Engenharia Biomédica, Portugal

2012/01/04 - 2012/12/19	Visiting Researcher (Research)	AO Research Institute Davos, Switzerland
	AO Research Institute Davos, Switzerland
2008/12/28 - 2011/12/31	Researcher (Research)	Instituto Nacional de Engenharia Biomédica, Portugal

Others

	Category Host institution	Employer
2017/09/01 - 2019/12/31	Doctoral Programme Managment	Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
	Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal (...)
2013/03/01 - 2017/02/28	PhD Student	Instituto Nacional de Engenharia Biomédica, Portugal
	Instituto Nacional de Engenharia Biomédica, Portugal (...)

Projects

Grant

	Designation	Funders
2013/03/01 - 2017/02/28	FCT PhD Fellowship: Mesenchymal stem/stromal cells recruitment for invertebral disc regeneration SFRH/BD/85779/2012 PhD Student Fellow Associação para a Inovação e Desenvolvimento da FCT, Portugal Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal	Associação para a Inovação e Desenvolvimento da FCT Concluded

Contract

	Designation	Funders
2022/06 - Current	LITWIN - Crohn’s & Colitis Foundation Research Litwin Researcher Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal	Ongoing
2022/01/01 - Current	HORIZON-HLTH-2021-TOOL-06: GENEGUT - Oral delivery of encapsulated RNA nanotherapeutics for targeted treatment of ileal Crohn's disease GENEGUT 101057491 Researcher Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal	European Comission Ongoing
2021 - Current	GILEAD GENESE: DUO-DIU Dispositivo intrauterino para co-libertação de levonorgestrel e de dapivirina Gilead GÉNESE Researcher Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal	Ongoing
2023/12/23 - 2025/05/23	MICKEY - Modelling osteosarcoma In vitro: a novel on-Chip platform to unravel KEY mechanisms of lung metastasis towards new therapies development and screening 2023.0009 Principal investigator Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2022/11/30 - 2023/11/30	Liga Portuguesa Contra o Cancro (LPCC): B2Tek-4OS - Bio-inspired and Bioengineered Technology for OSteosarcoma, unraveling OS to advance in novel targeted therapies NN 2023-25 CP Principal investigator Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal	Liga Portuguesa Contra o Cancro Ongoing
2020/02/16 - 2022/10	H2020: RESTORE - User-centred smart 3D nanobiomaterial-based scaffold for chondral repair 814558 Researcher Instituto Nacional de Engenharia Biomédica, Portugal	European Comission Ongoing
2019/01/01 - 2019/12/31	Instituto de Investigação e Inovação em Saúde UID/BIM/04293/2019 Instituto Nacional de Engenharia Biomédica, Portugal Universidade do Porto, Portugal Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2017/03 - 2019/12/31	Norte-01-0145-FEDER-000012: Bioengineered Therapies for infectious diseases and tissue regeneration Norte-01-0145-FEDER-000012 Post-doc Instituto Nacional de Engenharia Biomédica, Portugal	N/A Concluded
2017 - 2018/12/01	EUROSPINE Task Force 2017: Disc Regeneration, Immuno- and Neuro- modulation EUROSPINE_5_2017 Research Fellow Instituto Nacional de Engenharia Biomédica, Portugal	EUROSPINE The Spine Society of Europe Concluded
2015/07/27 - 2016/07/14	EUROSPINE Task Force 2015: Stem cells paracrine action for intervertebral disc regeneration EUROSPINE TRF_2015 Researcher Instituto Nacional de Engenharia Biomédica, Portugal	Concluded
2012/01/01 - 2013/12/31	AO SPINE: Mesenchymal stem/stromal cells recruitment for intervertebral disc regeneration AOSRN-104979 PhD Student Fellow AO Research Institute Davos, Switzerland Instituto Nacional de Engenharia Biomédica, Portugal	AOSpine International Concluded
2008/12/28 - 2012/12/31	FP7 DISC DEGENERATION: Novel biofunctional high porous polymer scaffolds and techniques controlling angiogenesis for the regeneration and repair of the degenerated intervertebral disc 213904 Research Fellow	European Commission Seventh Framework Programme for Research and Technological Development Concluded

Outputs

Publications

Book	Sarmento, Bruno; Leite Pereira, Catarina; das Neves, José. Concepts and Models for Drug Permeability Studies, 2 Edition. 2023. Accepted • Editor Sarmento, Bruno; Leite Pereira, Catarina; das Neves, José. Concepts and models for drug permeability studies: Cell and tissue based in vitro culture models. Portugal: Elsevier. 2023. In press
Book chapter	Leite Pereira, Catarina. "Organ-on-chip models for other mucosal permeability studies". In Concepts and Models for Drug Permeability Studies,. Elsevier, 2023. Accepted Pereira, Ana Catarina Leite; Grad, Sibylle; Barbosa, Mário Adolfo; Goncalves, Raquel M.. "Cell recruitment for degenerated intervertebral disc". In Gene and Cell Delivery for Intervertebral Disc Degeneration. CRC Press, 2018. Published
Conference abstract	Castro, Flávia; Marta Laranjeiro Pinto; Andreia Machado Silva; Leite Pereira, Catarina; Santos, Susana G.; Barbosa, Mário Adolfo; Olivier de Wever. Corresponding author: Castro, Flávia. "Harnessing chitosan/Poly(y)-glutamic acid nanoparticles for immunomodulation at the tumour microenvironment". Paper presented in 5th Biennial Congress of the European Association for Cancer Research (EACR25), Amesterdam, 2018. Published Castro, Flávia; Marta Laranjeiro Pinto; Andreia Machado Silva; Leite Pereira, Catarina; Olivier de Wever; Karine Serre; Raquel Madeira Gonçalves; Maria José Oliveira. "Reprogramming antigen-presenting cells: a chitosan/y-PGA nanoparticles for anticancer therapy". Paper presented in 8th International conference on Tumor Microenvironment: Progression, Therapy & Prevention, Lisbon, 2018. Published
Conference paper	Pereira, Ana Catarina Leite; R. Madeira Gonçalves; Peroglio, M.; G. Pattappa; D. Eglin; M. Adolfo Barbosa; M. Alini; Grad, S.. "Stromal Cell-Derived Factor-1 Delivery System: A New Approach for the Recruitment of Mesenchymal Stem Cells in Degenerating Intervertebral Disc". Paper presented in Global Spine Congress, 2014. Published • 10.1055/s-0034-1376645 Inês Odila; Pereira, Ana Catarina Leite; Molinos, Maria; R. M. Gonçalves; M. A. Barbosa. "An In Situ Anti-Inflammatory Drug Delivery System for Intervertebral Disks". Paper presented in Global Spine Congress, Helsínquia, 2012. Published Leite Pereira, Catarina; Gonçalves, Raquel Madeira; Dr. Frederico Ferreira-da-Silva; Antunes, Joana C.; Molinos, Maria; Barbosa, Mário Adolfo. Corresponding author: Barbosa, Mário Adolfo. "Biosynthesis of poly-gamma-glutamic acid and its application in the development of chitosan/poly-gamma-glutamic acid nanoparticles for drug delivery". Paper presented in 24th European Conference on Biomaterials - Annual Conference of the European Society for Biomaterials, Dublin, 2011. Published
Conference poster	Sofia Costa; Sarmento, Bruno; Leite Pereira, Catarina. "Multicellular tumor spheroids: modelling osteosarcoma as an in vitro tool to screen novel therapeutic strategies". Paper presented in Beyond REMODEL: 3R models for biomedical research, 2023. Sofia Costa; Sarmento, Bruno; Leite Pereira, Catarina. "Modeling Osteosarcoma as an in vitro 3D tool to screen novel therapies". Paper presented in 4th Young Scientist Meeting of the Spanish-Portuguese Local Chapter of CRS, 2023. Leite Pereira, Catarina. "PLGA-based nanoparticles for ibuprofen delivery - Targeting macrophages phenotype to modulate inflammation in cartilage degeneration". Paper presented in European Technology Platform Nanomedicine - ETPN 2022, 2022. NETO, ESTRELA; Monteiro, Ana Carolina; Leite Pereira, Catarina; Sarmento, Bruno; Lamghari, Meriem. "Nanodelivery systems to control inflammation in neurovascularized bone-on-a-chip model". Paper presented in European Technology Platform on Nanomedicine - ETPN 2022, 2022. Dias, Sofia; Leite Pereira, Catarina; Sarmento, Bruno. "3D Colorectal cancer spheroid model combined with a colon model for drug and nanoparticle safety and efficacy screening". Paper presented in 5th PhDay - Building Paths: The Science Behind Us, 2022. Castro, Flávia; Leite Pereira, Catarina; Gonçalves, Raquel; Oliveira, Maria José. "Chitosan/gamma-PGA nanoparticles-based immunotherapy as adjuvant to radiotherapy in breast cancer". Paper presented in Web Conference “Cancer Biology: from basic to Translational Research”, Portuguese Cancer Ligue, 2020. Castro, Flávia; Marta Laranjeiro Pinto; Leite Pereira, Catarina; Serre, Karine; Fátima Gartner; Mário Adolfo Barbosa ; Olivier de Wever; Raquel Madeira Gonçalves; Maria José Oliveira. "Reprogramming the breast tumor microenvironment: chitosan and poly(y-glutamic acid) nanoparticles in sight". Paper presented in 26th Porto Cancer Meeting: The Cancer Ecosystem: From Research to Pathology and Treatment, 2019. Castro, Flávia; Marta Laranjeiro Pinto; Leite Pereira, Catarina; Serre, Karine; Fátima Gartner; Mário Adolfo Barbosa ; Olivier de Wever; Raquel Madeira Gonçalves; Maria José Oliveira. "Chitosan/poly(y-glutamic acid) nanoparticles and radiotherapy: a winning combination to fight cancer". Paper presented in ASPIC International Meeting ¿ Current Trends in Immunotherapy Research and Treatment, Salamanca, Spain, 2019. Leite Pereira, Catarina. "Contribution of Chitosan (Ch) and poly(gamma)-glutamic (PGA) to the immunomodulatory role of Ch/PGA-based nanoparticles.". Paper presented in European Society for Biomaterials Conference, 2018. Pereira, Ana Catarina Leite. "SDF-1 mediated-mesenchymal stem cells recruitment: a new perspective for intervertebral disc degeneration treatment". Paper presented in eCM XVIII: Cartilage & Disc: Repair and Regeneration, 2018. Leite Pereira, Catarina. "Rat Intervertebral Disc Degeneration and Herniation Model for Local Biomaterial Delivery". Paper presented in European Society for Biomaterials Conference, 2017. Leite Pereira, Catarina. "Intervertebral Disc degeneration: cells navigation towards regeneration?". Paper presented in China-Europe Society for Biomaterials Conference, 2017. Castro, Flávia; Marta Laranjeiro Pinto; Leite Pereira, Catarina; Mário Adolfo Barbosa ; Raquel Madeira Gonçalves; Maria José Oliveira. "Reeducating antigen-presenting cells: an interferon-gamma delivery system for anticancer therapy". Paper presented in XI National Congress of the Italian Society of Immunology, clinical Immunology and allergology, Bari, Italy, 2017. Leite Pereira, Catarina. "Bioimaging Tools Towards the Quantification of Extracellular Matrix Production in Degenerating Intervertebral Discs". Paper presented in 4th International Symposium in Applied Bioimaging, 2015. Leite Pereira, Catarina. "Intradiscal application of anti-inflammatory nanoparticles control inflammation while remodel extracellular matrix of degenerated intervertebral disc". Paper presented in Advanced Summer School: Interrogations at the Biointerface - the Nano/Medicine Interface, 2015. Leite Pereira, Catarina. "Mesenchymal Stem migration in the intervertebral disc: a new route for regeneration through the activation of endogenous cells and increased matrix production.". Paper presented in 5th Advanced Summer School Interrogations at the Biointerface, 2015. Leite Pereira, Catarina. "Comparison of an anti-inflammatory drug delivery system versus MSC therapy to control inflammation in a pro-inflammatory intervertebral disc organ culture system". Paper presented in International Society for the Study of the Lumbar Spine (ISSLS) Annual Meeting, 2015. Leite Pereira, Catarina. "Stromal Cell Derived Factor-1-delivery system: a new approach for the recruitment of Mesenchymal Stem Cells in degenerating intervertebral disc". Paper presented in World Forum for Spine Research, 2014. Leite Pereira, Catarina. "Mesenchymal Stem Cells Recruitment by SDF-1 delivery in a degenerating Intervertebral Disc". Paper presented in 1st Symposium in Applied Bioimaging, 2013. Leite Pereira, Catarina. "Development of a chemoattractant delivery system for MSCs recruitment in the degenerated IVD". Paper presented in European Orthopaedic Research Society (EORS) Conference, 2012. Leite Pereira, Catarina. "Chitosan/Poly¿Glutamic Acid Nanoparticles as an anti-inflammatory drug delivery system for intervertebral disc". Paper presented in 9th World Biomaterials Conference, 2012. Leite Pereira, Catarina. "Layer-by-layer self-assembly of Chitosan and Poly(¿-glutamic acid) into polyelectrolyte complexes". Paper presented in 9th World Biomaterials Conference, 2012. 10.1021/bm2008235
Journal article	Barbara Ferreira; Cecilia Ferreira; Claudia Martins; Rute Nunes; José das Neves; Leite Pereira, Catarina; Sarmento, Bruno. "Establishment of a 3D Multi-layered In Vitro Model of Inflammatory Bowel Disease". Journal of Controlled Release (2024): Open access • Accepted Sofia Costa; João Rodrigues; Carolina Vieira; Sofia Dias; Juliana Viegas; Bruno Sarmento; Leite Pereira, Catarina. Corresponding author: Leite Pereira, Catarina. "Advancing osteosarcoma 3D modeling in vitro for novel tumor microenvironment-targeted therapies development". Journal of Controlled Release (2024): https://doi.org/10.1016/j.jconrel.2024.10.068. Accepted • https://doi.org/10.1016/j.jconrel.2024.10.068 Viegas, Juliana; Sofia Costa; Sofia Dias; Leite Pereira, Catarina; Sarmento, Bruno. "Patient-Derived Melanoma Immune-Tumoroids as a Platform for Precise High throughput Drug Screening". Advanced Science (2024): https://onlinelibrary.wiley.com/doi/10.1002/advs.202408707. Open access • Published • 10.1002/advs.202408707 Marina Couto; Daniela Pereira Vasconcelos; Catarina Leite Pereira; Estrela Neto; Bruno Sarmento; Meriem Lamghari. "Neuro-Immunomodulatory Potential of Nanoenabled 4D Bioprinted Microtissue for Cartilage Tissue Engineering". Advanced Healthcare Materials (2024): https://doi.org/10.1002/adhm.202400496. 10.1002/adhm.202400496 Cai, Zhengwei; Chen, Zhijie; Tang, Yuan; Cheng, Liang; Qiu, Minglong; Wang, Ningtao; Jiang, Wei; et al. "Bioinspired Bone Seed 3D-Printed Scaffold via Trapping Black Phosphorus Nanosheet for Bone Regeneration". Small Science (2024): http://dx.doi.org/10.1002/smsc.202300357. 10.1002/smsc.202300357 Daniela Pereira Vasconcelos; Catarina Leite Pereira; Marina Couto; Estrela Neto; Beatriz Ribeiro; Filipe Albuquerque; Alexandra Freitas; et al. "Nanoenabled Immunomodulatory Scaffolds for Cartilage Tissue Engineering". Advanced Functional Materials (2024): https://doi.org/10.1002/adfm.202400627. 10.1002/adfm.202400627 Ferreira, Bárbara; Barros, Andreia S.; Leite Pereira, Catarina; Viegas, Juliana; das Neves, José; Nunes, Rute; Sarmento, Bruno. "Trends in 3D models of inflammatory bowel disease". Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease (2024): 167042. http://dx.doi.org/10.1016/j.bbadis.2024.167042. Published • 10.1016/j.bbadis.2024.167042 Leite Pereira, Catarina; Grad, Sibylle; Gonçalves, Raquel M.. "Biomarkers for intervertebral disc and associated back pain: From diagnosis to disease prognosis and personalized treatment". JOR SPINE 6 4 (2023): http://dx.doi.org/10.1002/jsp2.1280. 10.1002/jsp2.1280 Qimanguli Saiding; Yiyao Chen; Juan Wang; Catarina Leite Pereira; Bruno Sarmento; Wenguo Cui; Xinliang Chen. "Abdominal wall hernia repair: from prosthetic meshes to smart materials". Materials Today Bio (2023): https://doi.org/10.1016/j.mtbio.2023.100691. 10.1016/j.mtbio.2023.100691 Domingues, Mariana; Leite Pereira, Catarina; Sarmento, Bruno; Castro, Flávia. "Mimicking 3D breast tumor-stromal interactions to screen novel cancer therapeutics". European Journal of Pharmaceutical Sciences (2023): 106560. http://dx.doi.org/10.1016/j.ejps.2023.106560. 10.1016/j.ejps.2023.106560 Carvalho, Suzana; Silveira, Maria José; Domingues, Mariana; Ferreira, Bárbara; Leite Pereira, Catarina; PalmiraGremião, Maria; Sarmento, Bruno. "Multicellular Quadruple Colorectal Cancer Spheroids as an In Vitro Tool for Anti-angiogenic Potential Evaluation of Nanoparticles". Advanced Therapeutics (2023): 2200282. http://dx.doi.org/10.1002/adtp.202200282. 10.1002/adtp.202200282 Catarina Leite Pereira; Meriem Lamghari; Bruno Sarmento. "Advances in nanoenabled 3D matrices for cartilage repair". Acta Biomaterialia (2022): https://doi.org/10.1016/j.actbio.2022.07.033. 10.1016/j.actbio.2022.07.033 Baião, Ana; Dias, Sofia; Soares, Ana Francisca; Leite Pereira, Catarina; Oliveira, Carla; Sarmento, Bruno. "Advances in the use of 3D colorectal cancer models for novel drug discovery". Expert Opinion on Drug Discovery 17 6 (2022): 569-580. http://dx.doi.org/10.1080/17460441.2022.2056162. 10.1080/17460441.2022.2056162 Neto, Estrela; Monteiro, Ana Carolina; Pereira, Catarina Leite; Simões, Miguel; Conde, João Pedro; Chu, Virginia; Sarmento, Bruno; Lamghari, Meriem. "Micropathological chip modelling the neurovascular unit response to inflammatory bone condition". Advanced Healthcare Materials (2022): 2102305. http://dx.doi.org/10.1002/adhm.202102305. Published • 10.1002/adhm.202102305 Rodrigues, João; Sarmento, Bruno; Pereira, Catarina Leite. "Osteosarcoma tumor microenvironment: the key for the successful development of biologically relevant 3D in vitro models". In vitro models (2022): http://dx.doi.org/10.1007/s44164-022-00008-x. 10.1007/s44164-022-00008-x Jiang, Wei; Hou, Fushan; Gu, Yong; Saiding, Qimanguli; Bao, Pingping; Tang, Jincheng; Wu, Liang; et al. "Local bone metabolism balance regulation via double-adhesive hydrogel for fixing orthopedic implants". Bioactive Materials 12 (2021): 169-184. http://dx.doi.org/10.1016/j.bioactmat.2021.10.017. 10.1016/j.bioactmat.2021.10.017 Cunha, Carla; Leite Pereira, Catarina; Ferreira, Joana R.; Ribeiro-Machado, Cláudia; Grad, Sibylle; Santos, Susana G.; Gonçalves, Raquel M.. "Therapeutic Strategies for IVD Regeneration through Hyaluronan/SDF-1-Based Hydrogel and Intravenous Administration of MSCs". International Journal of Molecular Sciences 22 17 (2021): 9609. http://dx.doi.org/10.3390/ijms22179609. 10.3390/ijms22179609 Flávia Castro; Catarina Leite Pereira; Maria Helena Macedo; Andreia Almeida; Maria José Silveira; Sofia Dias; Ana Patrícia Cardoso; et al. "Advances on colorectal cancer 3D models: The needed translational technology for nanomedicine screening". Advanced Drug Delivery Reviews 175 (2021): 113824-113824. https://doi.org/10.1016/j.addr.2021.06.001. In press • 10.1016/j.addr.2021.06.001 Castro, Flávia; Leite Pereira, Catarina; Macedo, Maria Helena; Almeida, Andreia; Silveira, Maria José; Cardoso, Ana Patricia; Oliveira, Maria José; Sarmento, Bruno. "Advances in Colorectal cancer 3D models: the needed translational technology for nanomedicine screening". Advanced Drug Delivery Reviews (2021): Accepted Ferreira, Joana Rita; Quelhas Teixeira, Graciosa; Neto, Estrela; Ribeiro-Machado, Cláudia; Silva, Andreia Machado; Caldeira, Joana; Leite Pereira, Catarina; et al. "IL-1ß-pre-conditioned Mesenchymal Stem/stromal Cells’ secretome modulates the inflammatory response and aggrecan deposition in intervertebral disc". eCells & Materials 41 (2021): 431-543. http://dx.doi.org/10.22203/ecm.v041a28. Accepted • 10.22203/ecm.v041a28 Castro, Flávia; Martins, Cláudia; Silveira, Maria José; Moura, Rui Pedro; Leite Pereira, Catarina; Sarmento, Bruno. "Advances on erythrocyte-mimicking nanovehicles to overcome barriers in biological microenvironments". Advanced Drug Delivery Reviews 170 (2021): 312-339. http://dx.doi.org/10.1016/j.addr.2020.09.001. 10.1016/j.addr.2020.09.001 Castro, Flávia; Pinto, Marta L.; Pereira, Catarina L.; Serre, Karine; Barbosa, Mário A.; Vermaelen, Karim; Gärtner, Fátima; et al. "Chitosan/¿-PGA nanoparticles-based immunotherapy as adjuvant to radiotherapy in breast cancer". Biomaterials 257 (2020): 120218. http://dx.doi.org/10.1016/j.biomaterials.2020.120218. 10.1016/j.biomaterials.2020.120218 Xu, Yichang; Gu, Yong; Cai, Feng; Xi, Kun; Xin, Tianwen; Tang, Jincheng; Wu, Liang; et al. "Metabolism Balance Regulation via Antagonist-Functionalized Injectable Microsphere for Nucleus Pulposus Regeneration". Advanced Functional Materials 30 52 (2020): 2006333. http://dx.doi.org/10.1002/adfm.202006333. 10.1002/adfm.202006333 Teixeira, José H.; Pereira, Catarina Leite; Almeida, Maria Inês; Teixeira, Graciosa Q.; Gonçalves, Raquel M.; Barbosa, Mário A.; Santos, Susana G.. "Articular Repair/Regeneration in Healthy and Inflammatory Conditions: From Advanced In Vitro to In Vivo Models". Advanced Functional Materials 30 44 (2020): 1909523. http://dx.doi.org/10.1002/adfm.201909523. 10.1002/adfm.201909523 Cunha, Carla; Q. Teixeira, Graciosa; Ribeiro-Machado, Cláudia; Leite Pereira, Catarina; Ferreira, Joana R.; Molinos, Maria; G. Santos, Susana; Barbosa, Mário A.; M. Goncalves, Raquel. "Modulation of the In Vivo Inflammatory Response by Pro- Versus Anti-Inflammatory Intervertebral Disc Treatments". International Journal of Molecular Sciences 21 5 (2020): 1730. http://dx.doi.org/10.3390/ijms21051730. 10.3390/ijms21051730 Flávia Castro; Marta L. Pinto; Rui Almeida; Flávia Pereira; Andreia M. Silva; Leite Pereira, Catarina; Susana G. Santos; et al. "Chitosan/poly(¿-glutamic acid) nanoparticles incorporating IFN-¿ for immune response modulation in the context of colorectal cancer". Biomaterials Science 7 8 (2019): 3386-3403. http://dx.doi.org/10.1039/c9bm00393b. 10.1039/c9bm00393b Leite Pereira, Catarina; Quelhas Teixeira, Graciosa; Rita Ferreira, Joana; D'Este, Matteo; Eglin, David; Alini, Maulo; Grad, Sibylle; Barbosa, Mário Adolfo; Gonçalves, Raquel Madeira. "Stromal Cell Derived Factor-1-Mediated Migration of Mesenchymal Stem Cells Enhances Collagen Type II Expression in Intervertebral Disc". Tissue Engineering Part A 24 23-24 (2018): 1818-1830. http://dx.doi.org/10.1089/ten.tea.2018.0131. 10.1089/ten.tea.2018.0131 Teixeira, Graciosa Q.; Pereira, Catarina Leite; Ferreira, Joana R.; Maia, André F.; Gomez-Lazaro, Maria; Barbosa, Mário A.; Neidlinger-Wilke, Cornelia; Goncalves, Raquel M.. "Immunomodulation of Human Mesenchymal Stem/Stromal Cells in Intervertebral Disc Degeneration". SPINE 43 12 (2018): E673-E682. http://dx.doi.org/10.1097/brs.0000000000002494. 10.1097/brs.0000000000002494 Antunes, J.C.; Pereira, C.L.; Teixeira, G.Q.; Silva, R.V.; Caldeira, J.; Grad, S.; Gonçalves, R.M.; Barbosa, M.A.. "Poly(¿-glutamic acid) and poly(¿-glutamic acid)-based nanocomplexes enhance type II collagen production in intervertebral disc". Journal of Materials Science: Materials in Medicine 28 1 (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-84996606963&partnerID=MN8TOARS. 10.1007/s10856-016-5787-1 Castro, F.; Pinto, M.L.; Silva, A.M.; Leite Pereira, Catarina; Teixeira, G.Q.; Gomez-Lazaro, M.; Santos, S.G.; et al. "Pro-inflammatory chitosan/poly(¿-glutamic acid) nanoparticles modulate human antigen-presenting cells phenotype and revert their pro-invasive capacity". Acta Biomaterialia 63 (2017): 96-109. http://www.scopus.com/inward/record.url?eid=2-s2.0-85030032238&partnerID=MN8TOARS. 10.1016/j.actbio.2017.09.016 Cunha, C.; Almeida, C.R.; Almeida, M.I.; Silva, A.M.; Molinos, M.; Lamas, S.; Pereira, C.L.; et al. "Systemic delivery of bone marrow mesenchymal stem cells for in situ intervertebral disc regeneration". Stem Cells Translational Medicine 6 3 (2017): 1029-1039. http://www.scopus.com/inward/record.url?eid=2-s2.0-85017568310&partnerID=MN8TOARS. 10.5966/sctm.2016-0033 Teixeira, Graciosa Q.; Leite Pereira, Catarina; Castro, Flávia; Ferreira, Joana R.; Gomez-Lazaro, Maria; Aguiar, Paulo; Barbosa, Mário A.; Neidlinger-Wilke, Cornelia; Goncalves, Raquel M.. "Anti-inflammatory Chitosan/Poly-y-glutamic acid nanoparticles control inflammation while remodeling extracellular matrix in degenerated intervertebral disc". Acta Biomaterialia 42 (2016): 168-179. http://dx.doi.org/10.1016/j.actbio.2016.06.013. 10.1016/j.actbio.2016.06.013 Ferreira, L.B.; Tavares, C.; Pestana, A.; Pereira, C.L.; Eloy, C.; Pinto, M.T.; Castro, P.; et al. "Osteopontin-a splice variant is overexpressed in papillary thyroid carcinoma and modulates invasive behavior". Oncotarget 7 32 (2016): 52003-52016. http://www.scopus.com/inward/record.url?eid=2-s2.0-84982293109&partnerID=MN8TOARS. 10.18632/oncotarget.10468 Pereira, C.L.; Teixeira, G.Q.; Ribeiro-Machado, C.; Caldeira, J.; Costa, M.; Figueiredo, F.; Fernandes, R.; et al. "Mesenchymal Stem/Stromal Cells seeded on cartilaginous endplates promote Intervertebral Disc Regeneration through Extracellular Matrix Remodeling". Scientific Reports 6 (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-84988672665&partnerID=MN8TOARS. 10.1038/srep33836 Teixeira, G.Q.; Boldt, A.; Nagl, I.; Pereira, C.L.; Benz, K.; Wilke, H.-J.; Ignatius, A.; et al. "A Degenerative/Proinflammatory Intervertebral Disc Organ Culture: An Ex Vivo Model for Anti-inflammatory Drug and Cell Therapy". Tissue Engineering - Part C: Methods 22 1 (2016): 8-19. http://www.scopus.com/inward/record.url?eid=2-s2.0-84954326138&partnerID=MN8TOARS. 10.1089/ten.tec.2015.0195 Gonçalves, R.M.; Pereira, A.C.L.; Pereira, I.O.; Oliveira, M.J.; Barbosa, M.A.. "Macrophage response to chitosan/poly-(¿-glutamic acid) nanoparticles carrying an anti-inflammatory drug". Journal of Materials Science: Materials in Medicine 26 4 (2015): http://www.scopus.com/inward/record.url?eid=2-s2.0-84925061574&partnerID=MN8TOARS. 10.1007/s10856-015-5496-1 Antunes, J.C.; Tsaryk, R.; Gonçalves, R.M.; Pereira, C.L.; Landes, C.; Brochhausen, C.; Ghanaati, S.; Barbosa, M.A.; Kirkpatrick, C.J.. "Poly(¿-Glutamic Acid) as an Exogenous Promoter of Chondrogenic Differentiation of Human Mesenchymal Stem/Stromal Cells". Tissue Engineering - Part A 21 11-12 (2015): 1869-1885. http://www.scopus.com/inward/record.url?eid=2-s2.0-84930157502&partnerID=MN8TOARS. 10.1089/ten.tea.2014.0386 Pereira, C.L.; Gonçalves, R.M.; Peroglio, M.; Pattappa, G.; D'Este, M.; Eglin, D.; Barbosa, M.A.; Alini, M.; Grad, S.. "The effect of hyaluronan-based delivery of stromal cell-derived factor-1 on the recruitment of MSCs in degenerating intervertebral discs". Biomaterials 35 28 (2014): 8144-8153. http://www.scopus.com/inward/record.url?eid=2-s2.0-84903746142&partnerID=MN8TOARS. 10.1016/j.biomaterials.2014.06.017 Pereira, C.L.; Antunes, J.C.; Gonçalves, R.M.; Ferreira-Da-Silva, F.; Barbosa, M.A.. "Biosynthesis of highly pure poly-¿-glutamic acid for biomedical applications". Journal of Materials Science: Materials in Medicine 23 7 (2012): 1583-1591. http://www.scopus.com/inward/record.url?eid=2-s2.0-84863314791&partnerID=MN8TOARS. 10.1007/s10856-012-4639-x Antunes, J.C.; Pereira, C.L.; Molinos, M.; Ferreira-Da-Silva, F.; Dessi, M.; Gloria, A.; Ambrosio, L.; Gonca¸lves, R.M.; Barbosa, M.A.. "Layer-by-layer self-assembly of chitosan and poly(¿-glutamic acid) into polyelectrolyte complexes". Biomacromolecules 12 12 (2011): 4183-4195. http://www.scopus.com/inward/record.url?eid=2-s2.0-84856258191&partnerID=MN8TOARS. 10.1021/bm2008235 Pereira, C.L.; Gonçalves, R.M.; Ferreira-Da-silva, F.; Antunes, J.C.; Molinos, M.; Barbosa, M.A.. "Biosynthesis of poly-¿-glutamic acid and its application in the development of chitosan/poly-¿-glutamic acid nanoparticles for drug delivery". 24th European Conference on Biomaterials - Annual Conference of the European Society for Biomaterials (2011): http://www.scopus.com/inward/record.url?eid=2-s2.0-84887002343&partnerID=MN8TOARS.
Thesis / Dissertation	Pereira, Ana Catarina Leite. "MESENCHYMAL STEM/STROMAL CELLS RECRUITMENT FOR INTERVERTEBRAL DISC REGENERATION". PhD, Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, 2017. Pereira, Ana Catarina Leite. "Biosynthesis of Poly-Gamma-Glutamic Acid and Its application in Chitosan/Poly-gamma-glutamic Acid Nanoparticles". Master, Universidade do Porto Faculdade de Engenharia, 2010.

Activities

Oral presentation

	Presentation title	Event name Host (Event location)
2024/02/15	Osteosarcoma Multicellular Spheroids Meet Microfluidics: A Tool to Screen New Therapeutical Strategies	XVth Spanish-Portuguese Conference on Controlled Drug Delivery Conference SPLC-CRS (Lisbon, Portugal)
2023/05/08	Invited Speaker at the Third Meeting of the PhD in Biomedical Sciences (ICBAS/UP): “From Biology, through Bioengineering, towards Biomedical applications”	Third Meeting of the PhD in Biomedical Sciences Instituto de Ciências Biomédicas Abel Salazar, University of Porto (Porto, Portugal)
2023/04/19	Invited Speaker at VIII Conferences in Oncology Research: "Bio-inspired and Bioengineered Technology for OSteosarcoma – unraveling OS to advance in novel targeted therapies"	VIII Conferences in Oncology Research Portuguese League Against Cancer (Lisbon, Portugal)
2022/03/31	Invited Speaker at the VII Bioengineering Week IST - Nanomedicine in treatment and diagnosis of diseases: "Nanomedicines for regenerative medicine"	VII Bioengineering Week of IST Instituto Superior Técnico, University of Lisbon (Lisbon, Portugal)
2021/07/26	PLGA-based nanoparticles for ibuprofen delivery - Targeting macrophages phenotype to modulate inflammation in cartilage degeneration	Controlled Release Society (CRS) 2021 Virtual Annual Meeting Controlled Release Society
2018/02/23	Invited Speaker at III Bioengineering Conferences from UTAD: "Bioengineering strategies for intervertebral disc degeneration and low back pain treatment"	III Bioengineering Conferences from UTAD University of Trans-os-Montes e Alto Douro (Vila Real, Portugal)
2017/10/06	Mesenchymal stem/stromal cells present an immunomodulatory role through paracrine mechanism in degenerated but not in healthy IVD	Eurospine Congress (Berlin, Germany)
2017/09/07	Hyaluronan-based hydrogel for SDF-1 delivery in the intervertebral disc: insights from an ex vivo model	European Society for Biomaterials Conference IEEE (Atenas, Greece)
2017/09/06	Chitosan/Poly-gamma-glutamic acid nanoperticles as the backbone of immunomodulatory therapies	European Society for Biomaterials Conference (Atenas, Greece)
2017	Mesenchymal Stem/Stromal Cells Recruitment from the Cartilaginous Endplate: a new perspective for IVD regenerative strategies through ECM remodeling	Tissue Engineering and Regenerative Medicine International Society Conference AO Research Institute (Davos, Switzerland)
2016/10/06	Extracellular Matrix Remodeling in intervertebral Disc by Mesenchymal Stem/Stromal Cells Recruitment from the Cartilaginous Endplate: a new perspective for IVD regenerative strategies	Eurospine Congress (Berlin, Germany)
2016/07/30	Local treatment of inflammation in degenerated intervertebral disc using poly(gamma-glutamic acid)-based nanocomplexes promotes extracellular matrix remodeling	Tissue Engineering and Regenerative Medicine International Society Conference (Uppsala, Sweden)
2016/06/30	Intervertebral Disc Regeneration: role of migrating MSCs in the Extracellular Matrix Remodeling	Tissue Engineering and Regenerative Medicine International Society Conference (Uppsala, Sweden)
2016/04/14	A nanotechnology-based therapy to target inflammation in degenerated intervertebral disc: first results from an ex vivo disc organ culture	Global Spine Congress/World Forum for Spine Research (Dubai, United Arab Emirates)
2016/03/04	Células estaminais/estromais mesenquimatosas através da endplate cartilaginea: uma nova rota no tratamento da degeneração do disco intervertebral	6º Congresso Nacional da Sociedade Portuguesa de Patologia da Coluna Vertebral (Vila Nova de Gaia, Portugal)
2015/10/13	Poly(gamma-glutamic acid) and poly(gamma-glutamic acid)-based nanocomplexes enhance type II collagen production in intervertebral disc	BIOMAT 2015 WORLD SCIENTIFIC (Ile de Ré, France)
2015/04/09	Intervertebral disc regeneration: the role of MSCs recruitment by hyaluronan-based delivery of SDF-1 in matrix production improvement.	BioSpine Congress IEEE (Berlin, Germany)
2015/04/09	Local treatment of inflammation and degeneration of intervertebral disc: ex vivo study of anti-inflammatory drug delivery system based on Chitosan/Poly-(gamma-Glutamic acid) nanoparticles	BioSpine Congress (Berlin, Germany)
2014/09/09	Development of a Chemoattractant Delivery System for Mesenchymal Stem Cells Recruitment to Intervertebral Disc	25th European Conference on Biomaterials (Madrid, Spain)
2014/09/01	Treatment of a degenerative/pro-inflammatory intervertebral disc organ culture with Chitosan/Poly-¿-glutamic acid nanoparticles carrying and anti-inflammatory drug	26th European Conference on Biomaterials (Liverpool, United Kingdom)
2011/09/05	Biosynthesis of ¿-Polyglutamic Acid and its application in the development of Chitosan/¿-Polyglutamic Acid Nanoparticles for Drug Delivery	24th European Conference on Biomaterials (Dublin, Ireland)
2011/07/08	Development of Chitosan-based Delivery System to recruit Mesenchymal Stem Cells	Tissue Engineering and Regenerative Medicine International Society Conference IEEE (Granada, Spain)
2011/04/05	Delivery system based on Chitosan/¿-Polyglutamic Polyelectrolyte Complexes recruits Mesenchymal Stem cells.	3rd Chinese-European Symposium on Biomaterials in Regenerative Medicine (Nanjing, China)
2011/03/23	Chemoattraction of Mesenchymal Stem Cells to intervertebral disc: design and characterization of a chemokine delivery system	Global Spine Congress (Barcelona, Spain)
2010/09/12	Development of Chitosan/Poly-¿-glutamic Acid Polyelectrolyte Complexes for Intervertebral Disc Degeneration	23rd European Conference on Biomaterials (Tampere, Finland)

Supervision

	Thesis Title Role	Degree Subject (Type) Institution / Organization
2024/09/16 - Current	Ana Cristina Duarte, MSc Candidate - Lung-on-chip platform development to study osteosarcoma metastasis and screening of nanotherapeutics Supervisor	Master (Master) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal Universidade de Coimbra, Portugal
2024/09/16 - Current	Maria Francisca Côrte-Real, MSc - Addressing Crohn's disease using bioengineering tools: Comprehensive characterization and validation of an immunocompetent 3D intestinal model as a screening platform for mRNA/siRNA-based therapies Supervisor	Master (Master) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal Universidade do Porto Faculdade de Engenharia, Portugal
2021/09 - 2025/09	Sofia Dias, PhD Candidate - 3D-CRCol: 3D organotypic ColoRectal Cancer spheroid model with healthy cOLon for drug and nanoparticle safety and efficacy screening Co-supervisor of Sofia Dias	Biomedical Sciences (PhD) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2020/11/01 - 2024/10/31	Diogo Horta, PhD Candidate: A swiss-knife nanotechnology approach to glioblastoma treatment Co-supervisor of Diogo de Freitas Horta	Neurosciences (PhD) Universidade do Porto, Portugal Universidade do Porto Faculdade de Medicina, Portugal
2024/03/05 - 2024/10/21	ERASMUS+ Student - Ilaria Gasperini, MSc - Approaching Crohn's Disease Treatments based on nanomedicines Supervisor	Medical Biotechnology (Master) Università degli Studi di Bologna, Italy
2024/02/01 - 2024/06/30	Carolina Vieira, BSc Internship - Development of nanoformulations for Osteossarcoma tumor microenvironment immunomodulation Supervisor	Bioengineering (Scientific initiation) Universidade do Porto Faculdade de Engenharia, Portugal
2021/06/01 - 2023/01/31	Cristina Santarcangelo, Visiting PhD Candidate: in vitro model system of the intestine to study nutraceuticals properties Co-supervisor	University of Napoli Federico II, Italy
2022/07/01 - 2023	Sofia Costa, MSc Candidate: Osteosarcoma (OS) Multicellular Tumor spheroids: modeling OS to address the potential of a nanotechnology-based immunomodulatory strategy in OS treatment Supervisor	Mestrado em Aplicações em Biotecnologia e Biologia Sintética (Master) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal Universidade do Porto Faculdade de Ciências, Portugal
2020/12/01 - 2021/07/31	João Rodrigues, MSc Candidate: Tumor-on-chip for Osteosarcoma (OS) drug screening: development of OS tumor microenvironment (TME)-compartment Supervisor of João Rodrigues	Bioengineering (Master) Universidade do Porto, Portugal
2021/01/02 - 2021/07/15	Beatriz Ribeiro, Trainee (BSc candidate) - Incorporation of anti-inflammatory nanoparticles in 3D scaffolds for articular cartilage regeneration Co-supervisor of Beatriz Ribeiro	BSc (Scientific initiation) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal Universidade do Porto Faculdade de Engenharia, Portugal
2017/09/18 - 2018/07/11	Rui Almeida (MSc Candidate): Immunomodulatory Nanoparticles for Intervertebral Disc Degeneration Supervisor of Rui Almeida	Mestrado Integrado em Bioengenharia (Master) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal Universidade do Porto Faculdade de Engenharia, Portugal
2018/04/02 - 2018/06/30	Leonor Correia, Trainee (BSc candidate): Imaging data Analysis of Intervertebral disc from human and bovine tissues Supervisor of Maria Leonor Correia	Mestrado Integrado em Bioengenharia (Degree) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal Universidade do Porto Faculdade de Engenharia, Portugal
2018/04/02 - 2018/06/30	Renata Basto, Trainee (BSc candidate): Histological processing and analysis of Intervertebral disc from human and bovine tissues Supervisor of Renata Basto	Mestrado Integrado em Bioenhenharia (Degree) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal Universidade do Porto Faculdade de Engenharia, Portugal
2017/02/16 - 2017/07/31	Rui Almeida, Trainee (BSc candidate): Design of nanocapsules based on chitosan/poly-gamma-glutamic acid electrostatic interaction for drug delivery Co-supervisor of Rui Almeida	Mestrado Integrado em Bioengenharia (Degree) Universidade do Porto Faculdade de Engenharia, Portugal Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Event organisation

	Event name Type of event (Role)	Institution / Organization
2013 - Current	Porto de Crianças - “Era uma vez…o osso e o sistema Imune: O exército que olha por nós” - with the aim to support the primary schools in their educational program, namely in the bone area. (2013) Other (Co-organisor)	Instituto Nacional de Engenharia Biomédica, Portugal
2011 - Current	“O INEB vai à Escola” created with the aim of increasing the awareness of high school students to the field of biomedical engineering and science in general (2011) Conference (Co-organisor)	Instituto Nacional de Engenharia Biomédica, Portugal
2022/10/01 - 2023/02/07	Organization of the 4th Spanish-Portuguese Local Chapter of the Controlled Release Society Young Scientist Meeting 2023 (2023/02/06 - 2023/02/07) Conference (President of the Organising Committee)	Spanish-Portuguese Local Chapter of the Controlled Release Society, Spain
2014/06/16 - 2014/06/26	INEB 25 ANOS: "A Engenharia Biomédica num Quarteirão de Histórias" A exposição consistiu numa forma divertida de explicar alguns dos principais projetos desenvolvidos no INEB nestes últimos 25 anos, associando-os a uma sardinha. (2014/06/16) Exhibition (Co-organisor)	Instituto Nacional de Engenharia Biomédica, Portugal

Event participation

	Activity description Type of event	Event name Institution / Organization
2011/03/17 - Current	MOSTRA DA UP: The Exhibition of the University of Porto is an annual event that aims to guide and raise awarness of Basic and Secondary Education students and the population in general, about the training offer and work carried out by the organic units belonging to the University of Porto. Exhibition	Universidade do Porto, Portugal
2020/10/14 - 2020/10/15	15th Annual ETPN – European Technology Platform on Nanomedicine event Congress	15th Annual Event European Technology Platform on Nanomedicine, France

Ad Hoc journal article review

	Journal title (ISSN)	Publisher
2023 - Current	SLAS Technology
2021 - Current	Particle and Particle Systems Characterization (1521-4117)	Wiley
2021 - Current	Drug Delivery and Translational Research (2190-3948)	Springer
2021 - Current	ACS applied materials & interfaces
2020 - Current	Drug Discovery Today (1359-6446)	Elsevier
2020 - Current	Acta Biomaterialia (1742-7061)	Elsevier
2020 - Current	Biomaterials Science (2047-4830)	The Royal Society of Chemistry
2019 - Current	Biomaterials (0142-9612)	Elsevier
2018 - Current	European Cells and Materials (1473-2262)
2023/03/01 - 2023/03/26	Wiley-VCH book proposal	Wiley-VCH book proposal

Association member

	Society Organization name	Role
2023/04/01 - Current	ASPIC - Associção Portuguesa de Investigação em Cancro (ASPIC627)
2023/04/01 - Current	EACR - European Association for Cancer Research
2022/01/01 - Current	SPLC-CRS: Spanish-Portuguese Local Chapter of Controled Release Society	Young Scientist Board Member
2020 - Current	CRS - Controlled Release Society
2011 - Current	ESB - European Society for Biomaterials
2015 - 2016	AO SPINE

Committee member

	Activity description Role	Institution / Organization
2022/07 - Current	PhD Advisory Committee member - PhD Candidate Inês Saraiva (FCT Maria de Sousa Fellows, IMM, Faculty of Medicine of University of Lisbon) Advisor / Consultant	Universidade de Lisboa Faculdade de Medicina, Portugal
2021/07 - Current	PhD Advisory Committee member - PhD Candidate Emine Kahraman (Doctoral Program in Biomedical Engineering, FEUP) Advisor / Consultant	Universidade do Porto Faculdade de Engenharia, Portugal

Conference scientific committee

	Conference name	Conference host
2021/12/01 - 2023/06/07	4th SPLC-CRS Young Scientists Meeting - Bridging Science, Delivering Oportunities	SPLC-CRS Young Scientist Board
2022/10/01 - 2022/10/04	5th PhDay: “Building Paths: The Science Behind Us”	i3S
2022/02/28 - 2022/03	Controlled Release Society (CRS) Annual Meeting and Expo 2022	CRS
2021/04 - 2021/09	31st Conference of the European Society for Biomaterials 2021	ESB/INEB
2021/02 - 2021/03	Controlled Release Society (CRS) Virtual Annual Meeting 2021	CRS
2018/05/01 - 2018/05/30	1st PhDay at i3S - From bench to stage, from desk to forum	i3S

Course / Discipline taught

	Academic session	Degree Subject (Type)	Institution / Organization
2022 - Current	"Nanomedicines for regenerative medicine" - Curricular Unit in Nanotechnology in Health of the Biongineering BSc course of ICBAS/UP	Bioengineering (Bacharelato)	Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2021/09/17 - Current	"Nanomedicine in Regenerative Medicine" in Advanced Course in Nanotechnology, Drug Delivery and Drug Targeting, CESPU	Doctoral Program of Biological Sciences Applied to Health (Doutoramento)	Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2023/03/22 - 2023/03/22	COST ACTION GEMSTONE Trainning Schoool- "In vitro 3D modeling of osteosarcoma at the cellular and ECM level: technical highlights and challenges	In vitro 3D modeling (Doutoramento)	Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Evaluation committee

	Activity description Role	Institution / Organization	Funding entity
2023/02/01 - Current	Invited External Reviewer for the Research Prize of The Lister Institute of Preventive Medicine Evaluator	The Lister Institute of Preventive Medicine, United Kingdom	The Lister Institute of Preventive Medicine
2023 - Current	Graduate Women in Science (GWIS) National Fellowship Program application 2023 Evaluation Evaluator	Graduate Women in Science (GWIS) , United States
2021 - Current	Invited external grant reviewer for the National Science Centre (NCN) Poland Evaluator		Narodowe Centrum Nauki

Interview (newspaper / magazine)

	Activity description	Newspaper / Forum
2022/07/26	€5.4 million project aims to create oral therapy for Crohn's Disease - "researchers will receive 400,000 euros to develop a three-dimensional (3D) model that simulates the "inflamed intestine" of this disease and can be used "to test the effectiveness of nanomedicines" .	Expresso
2021/12/22	Interview about the pize of Liga Portuguesa Contra o Cancro (15K euros award) - General Public Dissemination	Noticias UP
2019/11/18	i3S: o dia a dia do instituto que vira o cancro do avesso (Cancer dedicated day of i3S) - General Public Dissemination	Noticias Magazzine

Interview (tv / radio show)

	Program	Topic
2022/07/27 - Current	National News - GENEGUT Press release: dissemination of project goal and focus of i3S team, to the general public	European Project Genegut
2021/10 - 2021/10	Porto Canal (National TV Channel) - Somos Academia - Role of science in Postgraduate Studies	Research-academia interaction in our research group at Instituto de Investigação e Inovação em Saúde. Scientific training, transversal skills, communication tools and innovation, the key players.

Distinctions

Award

2023	Innovate Competition da iMed Conference® 15.0 AstraZeneca AB, Sweden Faculdade de Ciências Médicas da Universidade Nova de Lisboa, Portugal
2022	Award Nonô Sarcoma Pediatrico Liga Portuguesa Contra o Cancro, Portugal
2018	Julia Polak European Doctoral Award European Society for Biomaterials, France
2016	3rd Place, Best Research Article Award
2015	Best Poster Presentation Award at Advanced Summer School: THE NANO / MEDICINE INTERFACE
2015	AO Spine European Young Researcher Award AOSpine International, Switzerland
2013	Best Poster Presentation Award at the International Symposium in Applied Bioimaging Instituto Nacional de Engenharia Biomédica, Portugal