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I am currently a research fellow at the Center for Neuroscience and Cell Biology of the University of Coimbra (CNC-UC), within the scope of the project "SynBridge - A New TransSynaptic Bridge: Functional Characterization of the Interaction between the NMDA Receptor and Neurexin" (https://doi. org/10.54499/2022.05386.PTDC) where I am collaborating in the study of the interaction between two important synaptic players, the GluN2B subunit of the N-methyl-D-aspartate receptors (NMDARs) and the presynaptic molecule Neurexin2 (Nrxn2). I recently completed my Master's Degree in Biomedical Research at the Faculty of Medicine – University of Coimbra, having obtained a grade of 18 (grading system from 1 to 20, grade A on the ECTS scale). I did my master's thesis at CNC-UC, on the role of GluN2B-containing NMDARs in synapse function and their potential interaction with the EphA4 receptor. I developed various technical skills in molecular and cell biology (e.g., preparation and transfection of neuronal cultures, DNA extraction and PCR, maintenance and transfection of heterologous cell lines), and biochemistry (e.g., western blot, subcellular fractionation, immunoprecipitation assays). I graduated with honors in 2021 from CESPU (Cooperativa de Ensino Superior Politécnico e Universitário, Porto, Portugal), a higher education institution dedicated to health sciences, with a grade of 16 (grading system from 1 to 20, grade B on the ECTS scale). During my degree (2020 to 2021), I worked as a researcher at the Institute for Research and Advanced Training in Health Sciences and Technologies (Porto, Portugal) , where I acquired technical skills (e.g. isolation of bacteria, DNA extraction and purification, bioinformatics, antibiotic sensitivity tests, compound screening and checkerboard assays) and began developing what would become their microbiology research project "Halogenated salicylates and possible synergies with antibiotics in inhibiting the growth of Staphylococcus aureus strains" , obtaining a grade of 18. I have been selected to take part in the European Commission's Horizon Europe Young Observer program, which aims to monitor the evaluation stages of competitive European research calls. I also have training in animal experimentation, with a final grade of 16.2 (grading system from 1 to 20). I took two postgraduate doctoral courses on synapse biology. I participated in the Draw your Science challenge, where I presented the results obtained during my MSc work, volunteered to collaborate with the Centre for Innovative Biomedicine and Biotechnology. (CIBB) Neuroscience and Disease area retreat, the associate laboratory that integrates CNC-UC. Completed the CNC winter school focused on soft skills and EIT Health i-Days focused on entrepreneurship. I have been selected from abstracts submission to present my work at the Annual International (bio)Medical Students Meeting (AIMS) in Lisbon and at the Multidisciplinary Institute of Ageing (MIA) Spring School. I mentored a laboratory rotation student for a month on the Master's degree in Cellular and Molecular Biology at the Faculty of Science and Technology of the University of Coimbra. I am currently mentoring an Erasmus student from Spain, on her laboratory work, part of her degree dissertation as part of the SynBridge project.
Identification

Personal identification

Full name
João Gonçalves Martins

Citation names

  • Gonçalves-Martins, J.

Author identifiers

Ciência ID
AA1F-E787-93E9
ORCID iD
0000-0003-1487-4211

Email addresses

  • joaomartins@cnc.uc.pt (Professional)

Addresses

  • CNC-Centro de Neurociências e Biologia Celular & Departamento de Ciências da Vida, Universidade de Coimbra. Rua Larga, 3004-504, Coimbra, Coimbra, Portugal (Professional)

Websites

Knowledge fields

  • Medical and Health Sciences - Basic Medicine - Neurosciences

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Advanced (C1) Proficiency (C2) Proficiency (C2) Proficiency (C2)
Education
Degree Classification
2024/10 - 2029
Ongoing
Doctoral Programme in Experimental Biology and Biomedicine (Doutoramento)
Major in Neurosciences
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2024/01/29 - 2024/02/02
Concluded
CNC Advanced Course: Synapse assembly, function and plasticity (Curso de doutoramento (conclusão de unidades curriculares))
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
18
2023/12/11 - 2023/12/15
Concluded
Neuroscience meets society: transversal skills for future neuroscientists (Outros)
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2021/10/12 - 2023/10/23
Concluded
Mestrado em Investigação Biomédica (Mestrado)
Major in Neurobiologia
Universidade de Coimbra Faculdade de Medicina, Portugal
"Role of GluN2B-containing NMDARs on network activity and synapse maturation and its potential interaction with EphA4" (THESIS/DISSERTATION)
18
2023/01/29 - 2023/02/02
Concluded
From synapses to circuits and brain diseases. Module 1: Synapse assembly, function and plasticity (Curso de doutoramento (conclusão de unidades curriculares))
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
18
2023
Attended
From synapses to circuits and brain diseases. Module 2: Neuronal Circuits and Behavior Course (Curso de doutoramento (conclusão de unidades curriculares))
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2023
Attended
From synapses to circuits and brain diseases. Module 3 - Pathogenic Mechanisms in Neuropsychiatric and Neurodegenerative Disorders (Curso de doutoramento (conclusão de unidades curriculares))
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2022/04/11 - 2022/04/29
Concluded
Rotação laboratorial III (Outros)
Major in Neurociências
Universidade de Coimbra Faculdade de Medicina, Portugal

Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
18
2022/03/14 - 2022/04/08
Concluded
Rotação laboratorial II (Outros)
Universidade de Coimbra Faculdade de Medicina, Portugal

Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
19
2022/03/07 - 2022/03/11
Concluded
Do Genótipo ao Fenótipo (Curso de doutoramento (conclusão de unidades curriculares))
Universidade de Coimbra Faculdade de Medicina, Portugal
18
2022/02/28 - 2022/03/04
Concluded
Imunologia (Curso de doutoramento (conclusão de unidades curriculares))
Universidade de Coimbra Faculdade de Medicina, Portugal
17
2022/01/24 - 2022/02/11
Concluded
Rotação laboratorial I (Outros)
Major in Microbiologia
Universidade de Coimbra Faculdade de Medicina, Portugal

Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
19
2022/01/17 - 2022/01/21
Concluded
Investigação em Neurobiologia (Curso de doutoramento (conclusão de unidades curriculares))
Universidade de Coimbra Faculdade de Medicina, Portugal
18
2021/11/15 - 2022/01/16
Concluded
Experimentação Animal (Outros)
Universidade de Coimbra Faculdade de Medicina, Portugal
16,2
2018/09/02 - 2021/07/08
Concluded
Ciências Biomédicas (Licenciatura)
Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
"Halogenated salicylates and possible synergies with antibiotics in inhibiting the growth of Staphylococcus aureus strains" (THESIS/DISSERTATION)
16
Affiliation

Science

Category
Host institution
Employer
2023/12/18 - 2024/12/23 Researcher (Research) Universidade de Coimbra, Portugal
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2020/03/06 - 2021/06/09 Researcher (Research) Instituto de Investigação e Formação Avançada em Ciências e Tecnologias da Saúde, Portugal
Instituto de Investigação e Formação Avançada em Ciências e Tecnologias da Saúde, Portugal
(...)
Projects

Contract

Designation Funders
2023/12/18 - 2024/08/31 New TransSynaptic Bridge: Functional characterization of the interaction between NMDA receptors and Neurexins
2022.05386.PTDC
Research Fellow
Universidade de Coimbra, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
Outputs

Publications

Conference poster
  1. Gonçalves-Martins, J.; Ferreira, Joana S. "Role of GluN2B-containing NMDARs on network activity and synapse maturation and its potential interaction with EphA4". Paper presented in BEB Day 2024 - (Not) Knowing What Comes Next: Tools for the Research of Tomorrow, 2024.
  2. Gonçalves-Martins, J.; Carvalho, Ana Luisa; Ferreira, Joana S. "Role of GluN2B-containing NMDARs on network activity and synapse maturation and its potential interaction with EphA4". Paper presented in AIMS Meeting – Annual International (bio) Medical Students Meeting, 2024.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2024/05/28 Role of GluN2B-containing NMDARs on EphA4 synaptic localization and mediated activity MIA-Portugal Ageing Spring School
MIA - Multidisciplinary Institute for Ageing (Coimbra, Portugal)

Event participation

Activity description
Type of event
Event name
Institution / Organization
2023/12/20 - 2023/12/20 Participated in the Draw Your Science Challenge at the CIBB Meeting 2023. The Annual Meeting serves as a platform for CIBB researchers to come together, not only to discuss scientific advances and celebrate the achievements of the past year, but also to spark new ideas and foster scientific collaborations for the coming year.
Meeting
CIBB Meeting 2023
Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia, Portugal
2023/11/07 - 2023/11/11 Cantanhe i-Days gave training dedicated to innovation, design thinking and entrepreneurship, promoting teamwork among the various participants who tried to solve real challenges posed by different health organizations. EIT Health Innovation Days (i-Days)
EIT Health, Germany
2023/06/02 - 2023/06/02 Volunteered at the the 5th Annual Retreat for Neuroscience and Disease. An informal gathering focused on fostering debate and interaction among participants. There were scientific presentations covering diverse topics. The retreat also provided opportunities for researchers to showcase their work through posters and videos.
Meeting
5th Retreat Neuroscience & Disease
Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia, Portugal

Mentoring / Tutoring

Topic Student name
2024/03 - 2024/06 A New TransSynaptic Bridge: Functional characterization of the NMDA receptor-Neurexin interaction Camila Bové de Souza
2024/01/29 - 2024/02/23 Study of the interaction between synaptic proteins: NMDARs and neurexins Bárbara Esteves Dias
Distinctions

Award

2021 Best finalist
Cooperativa de Ensino Superior Politécnico e Universitário, Portugal

Other distinction

2022 Horizon Europe Young Observer
Horizon Europe, Belgium